{"id":4367,"date":"2024-06-25T21:15:29","date_gmt":"2024-06-25T12:15:29","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/aga\/best-drugs-to-combine-with-finasteride\/"},"modified":"2026-07-28T06:20:02","modified_gmt":"2026-07-27T21:20:02","slug":"best-drugs-to-combine-with-finasteride-en","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/aga\/best-drugs-to-combine-with-finasteride-en\/","title":{"rendered":"What Medications Should I Take With Finasteride?"},"content":{"rendered":"\n<p>There are several options for drugs and treatments that can be used in combination with finasteride to maximize the effectiveness of treating <a href=\"https:\/\/www.hiro-clinic.or.jp\/aga\/\">AGA<\/a> (androgenetic alopecia). Below are medications and treatments that are commonly recommended for use with finasteride.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. Minoxidil<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Effect<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mechanism of action<\/strong>: Minoxidil is a vasodilator that increases blood circulation, increases the supply of nutrients to the hair follicles, and promotes hair growth.<\/li>\n\n\n\n<li><strong>Effect<\/strong>: When used in combination with finasteride, it can be expected to increase hair density and increase hair growth.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>How to use<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Topical medicine<\/strong>: Apply minoxidil solution or foam directly to the scalp twice a day.<\/li>\n\n\n\n<li><strong>Oral medicine<\/strong>: In some cases it may be used as an oral medication, but this is usually done under the supervision of a doctor.<\/li>\n<\/ul>\n\n\n\n<p>Spironolactone is often used as a diuretic, but it also has anti-androgenic properties and is sometimes used to treat hair loss in women.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. Spironolactone<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Mechanism of action<\/strong><\/h4>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Anti-androgenic effect<\/strong>:\n<ul class=\"wp-block-list\">\n<li>Spironolactone binds to androgen receptors and prevents androgens (testosterone and DHT) from binding to the receptors.<\/li>\n\n\n\n<li>This has the effect of suppressing the effect of androgens on the hair follicles and slowing down the progression of hair loss.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Aldosterone antagonism<\/strong>:\n<ul class=\"wp-block-list\">\n<li>Spironolactone also acts as an aldosterone receptor antagonist and has diuretic effects that promote sodium and water excretion.<\/li>\n\n\n\n<li>Although the diuretic effect itself is not directly related to <a href=\"https:\/\/www.hiro-clinic.or.jp\/aga\/\">AGA<\/a> treatment, the anti-androgenic effect helps suppress hair loss.<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>How to use<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Oral medicine<\/strong>: Spironolactone is prescribed as a tablet and is usually recommended to be taken once or twice a day. Your doctor will determine the dosage depending on your individual symptoms.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Effect<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Female pattern hair loss<\/strong>: Spironolactone is particularly effective <a href=\"\">aga<\/a>inst female pattern hair loss, and can be expected to suppress the progression of hair loss by regulating hormone balance.<\/li>\n\n\n\n<li><strong>Men&#8217;s use<\/strong>: It should be used with caution in men as it has a strong anti-androgenic effect. It may be considered as an adjunctive option, especially in men, when finasteride or dutasteride treatment is ineffective, but it must be used under the supervision of a doctor due to the high risk of side effects.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Side effect<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>woman<\/strong>: Side effects such as irregular menstruation, breast tenderness, and increased blood potassium concentration have been reported.<\/li>\n\n\n\n<li><strong>male<\/strong>: Side effects such as decreased libido, erectile dysfunction, and breast enlargement have been reported, and it has a strong suppressive effect on male hormones, so it must be used with caution.<\/li>\n\n\n\n<li><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. Corticosteroids<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Effect<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mechanism of action<\/strong>: It has anti-inflammatory properties and is effective in suppressing damage to hair follicles caused by autoimmune reactions.<\/li>\n\n\n\n<li><strong>Effect<\/strong>: Used especially when a combination of alopecia areata is suspected.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>How to use<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Topical medicine<\/strong>: Steroid lotions and creams that are applied directly to the scalp.<\/li>\n\n\n\n<li><strong>Oral medicine<\/strong>: In severe cases, oral steroids may be prescribed.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4. Low-Level Laser Therapy (LLLT)<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Effect<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Mechanism of action<\/strong>: It is believed that the low-power laser stimulates the cells in the hair follicle, increasing blood circulation and promoting hair growth.<\/li>\n\n\n\n<li><strong>Effect<\/strong>: When used in combination with finasteride, it can be expected to improve hair growth and density.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>How to use<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Device<\/strong>: Treatment is performed regularly using a helmet-type or comb-type device.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5. Lifestyle improvements and supplements<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Effect<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Nutritional support<\/strong>: Adequate nutrient intake is important for healthy hair growth.<\/li>\n\n\n\n<li><strong>Effect<\/strong>: Supports hair health by supplying nutrients such as vitamins, minerals, zinc, and iron as supplements.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>How to use<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Balanced diet<\/strong>: Eat healthy and get the nutrients you need.<\/li>\n\n\n\n<li><strong>Supplement<\/strong>: Use nutritional supplements as needed.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Summary<\/strong><\/h3>\n\n\n\n<p>Medications and treatments that can be used in conjunction with finasteride to enhance the effectiveness of <a href=\"https:\/\/www.hiro-clinic.or.jp\/aga\/\">AGA<\/a> treatment include minoxidil, dutasteride, corticosteroids, low-power laser therapy, and lifestyle changes and supplements. By combining these treatments, we can expect more effective <a href=\"https:\/\/www.hiro-clinic.or.jp\/aga\/\">AGA<\/a> treatment. It is important to determine the most appropriate treatment plan under the guidance of a specialist, depending on your individual symptoms and circumstances.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>There are several options for drugs and treatments that can be used in combination wi&#8230;<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"meta_title":"","meta_description":"","footnotes":""},"categories":[51],"tags":[],"class_list":{"0":"post-4367","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-aga-en","7":"article"},"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/posts\/4367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/comments?post=4367"}],"version-history":[{"count":1,"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/posts\/4367\/revisions"}],"predecessor-version":[{"id":4370,"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/posts\/4367\/revisions\/4370"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/media?parent=4367"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/categories?post=4367"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/aga\/wp-json\/wp\/v2\/tags?post=4367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}