{"id":4521,"date":"2025-03-28T13:59:27","date_gmt":"2025-03-28T04:59:27","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/dermatology\/?p=4521"},"modified":"2025-04-24T17:39:05","modified_gmt":"2025-04-24T08:39:05","slug":"molefaq","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/dermatology\/derma\/molefaq\/","title":{"rendered":"\u305d\u306e\u201c\u307b\u304f\u308d\u201d\u3001\u672c\u5f53\u306b\u5927\u4e08\u592b\uff1f\u76ae\u819a\u304c\u3093\u306e\u8aa4\u89e3\u3092\u3084\u3055\u3057\u304f\u89e3\u8aac"},"content":{"rendered":"\n<div style=\"height:12px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-align-center\"><sup>\u30ad\u30fc\u30ef\u30fc\u30c9\uff1a\u307b\u304f\u308d,\u76ae\u819a\u304c\u3093,\u8272\u7d20\u6027\u6bcd\u6591,\u30e1\u30e9\u30ce\u30fc\u30de,\u60aa\u6027\u9ed2\u8272\u816b,\u8db3\u306e\u88cf\u306e\u307b\u304f\u308d,\u307b\u304f\u308d \u5207\u9664,\u5916\u50b7 \u307b\u304f\u308d,\u6bcd\u6591\u304c\u3093\u5316,\u65e5\u713c\u3051\u6b62\u3081 \u307b\u304f\u308d,\u90e8\u5206\u751f\u691c,\u30bb\u30f3\u30c1\u30cd\u30eb\u30ea\u30f3\u30d1\u7bc0\u751f\u691c,\u30b9\u30d4\u30c3\u30c4\u6bcd\u6591,dysplastic nevus,melanocytic nevus,acral melanoma,nail apparatus melanoma,\u7d2b\u5916\u7dda \u30c0\u30e1\u30fc\u30b8,\u9ad8\u6821\u751f \u76ae\u819a,\u76ae\u819a\u79d1 \u6b63\u3057\u3044\u77e5\u8b58,\u76ae\u819a\u304c\u3093 \u8aa4\u89e3,\u82e5\u5e74\u5c64 \u76ae\u819a\u304c\u3093\u30ea\u30b9\u30af,\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af<\/sup><\/p>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u533b\u5b66\u7684\u306a\u8aa4\u89e3\u3068\u76ae\u819a\u306e\u8272\u7d20\u6027\u75c5\u5909\uff1a\u5e83\u304f\u4fe1\u3058\u3089\u308c\u3066\u3044\u308b\u300c\u307b\u304f\u308d\u795e\u8a71\u300d\u306e\u79d1\u5b66\u7684\u691c\u8a3c<\/h2>\n\n\n\n<p>\u533b\u5b66\u306e\u6b74\u53f2\u306f\u3001\u8aa4\u89e3\u3084\u8ff7\u4fe1\u304c\u4e8b\u5b9f\u306e\u3088\u3046\u306b\u8a9e\u3089\u308c\u3001\u9577\u3044\u9593\u4fe1\u3058\u3089\u308c\u3066\u304d\u305f\u4f8b\u306b\u6e80\u3061\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u76ae\u819a\u79d1\u9818\u57df\u3001\u3068\u308a\u308f\u3051\u8272\u7d20\u6027\u76ae\u819a\u75c5\u5909\uff08pigmented skin lesions\uff09\u3001\u3064\u307e\u308a\u300c\u307b\u304f\u308d\u300d\u3084\u300c\u6bcd\u6591\uff08melanocytic nevi\uff09\u300d\u306b\u95a2\u3059\u308b\u795e\u8a71\u3084\u8aa4\u89e3\u306f\u6839\u5f37\u304f\u3001\u591a\u304f\u306e\u60a3\u8005\u3084\u533b\u7642\u5f93\u4e8b\u8005\u3055\u3048\u3082\u4fe1\u3058\u3066\u3044\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u672c\u7a3f\u3067\u306f\u3001\u76ae\u819a\u306e\u8272\u7d20\u6027\u75c5\u5909\u306b\u95a2\u3059\u308b\u4ee3\u8868\u7684\u306a7\u3064\u306e\u8aa4\u89e3\u3092\u53d6\u308a\u4e0a\u3052\u3001\u305d\u308c\u305e\u308c\u306b\u3064\u3044\u3066\u305d\u306e\u8d77\u6e90\u3068\u3001\u306a\u305c\u305d\u308c\u304c\u8aa4\u308a\u3067\u3042\u308b\u306e\u304b\u3092\u3001\u79d1\u5b66\u7684\u8a3c\u62e0\u3092\u3082\u3068\u306b\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002\u306a\u304a\u3001\u3053\u306e\u30ec\u30d3\u30e5\u30fc\u306e\u4e00\u90e8\u306f\u30012015\u5e742\u670815\u65e5\u304b\u30893\u670815\u65e5\u306b\u304b\u3051\u3066\u30a4\u30bf\u30ea\u30a2\u306e\u5973\u6027\u5411\u3051\u5065\u5eb7\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8\u300cVediamociChiara.it\u300d\u3067\u5b9f\u65bd\u3055\u308c\u305f\u30aa\u30f3\u30e9\u30a4\u30f3\u30a2\u30f3\u30b1\u30fc\u30c8\uff08\u5bfe\u8c61\uff1a\u6210\u4eba\u5973\u60271,024\u4eba\uff09\u306e\u7d50\u679c\u3092\u3082\u3068\u306b\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"480\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/23916547_s.jpg\" alt=\"\u30a4\u30bf\u30ea\u30a2\u4eba\u306e\u5973\u6027\" class=\"wp-image-4526\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/23916547_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/23916547_s-300x225.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u307b\u304f\u308d\u3092\u5207\u9664\u3059\u308b\u3068\u5371\u967a\u306a\u306e\u304b\uff1f<\/h2>\n\n\n\n<p>\u300c\u307b\u304f\u308d\u3092\u53d6\u308b\u3068\u304c\u3093\u306b\u306a\u308b\u300d\u3068\u3044\u3063\u305f\u4e0d\u5b89\u306f\u3001\u591a\u304f\u306e\u4eba\u3005\u306e\u9593\u3067\u6839\u5f37\u304f\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u3002\u5b9f\u969b\u3001\u4e0a\u8a18\u306e\u30a2\u30f3\u30b1\u30fc\u30c8\u3067\u306f\u300182\uff05\u306e\u5973\u6027\u304c\u300c\u307b\u304f\u308d\u306e\u5207\u9664\u306f\u5371\u967a\u3067\u3042\u308b\u300d\u3068\u56de\u7b54\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u8aa4\u89e3\u306e\u80cc\u666f\u306b\u306f\u3001\u9032\u884c\u3057\u305f\u30e1\u30e9\u30ce\u30fc\u30de\uff08melanoma\uff1a\u76ae\u819a\u304c\u3093\u306e\u4e00\u7a2e\uff09\u306e\u5207\u9664\u5f8c\u306b\u6025\u6fc0\u306b\u8ee2\u79fb\uff08metastasis\uff09\u304c\u9032\u884c\u3059\u308b\u75c7\u4f8b\u304c\u3042\u308b\u3053\u3068\u304c\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u75c7\u4f8b\u3092\u898b\u308b\u3068\u3001\u60a3\u8005\u3084\u5bb6\u65cf\u306f\u300c\u5207\u9664\u304c\u539f\u56e0\u3067\u60aa\u5316\u3057\u305f\u300d\u3068\u611f\u3058\u3066\u3057\u307e\u3046\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u73fe\u4ee3\u306e\u7814\u7a76\u306b\u3088\u3063\u3066\u3001\u30e1\u30e9\u30ce\u30fc\u30de\u306f\u514d\u75ab\u539f\u6027\u816b\u760d\uff08immunogenic tumor\uff09\u3067\u3042\u308a\u3001\u4f53\u306e\u514d\u75ab\u7cfb\uff08immune system\uff09\u304c\u3042\u308b\u7a0b\u5ea6\u305d\u306e\u5897\u6b96\u3092\u6291\u3048\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u9032\u884c\u3057\u305f\u816b\u760d\u3092\u5207\u9664\u3059\u308b\u3053\u3068\u3067\u3053\u306e\u514d\u75ab\u7684\u306a\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u3001\u7d50\u679c\u7684\u306b\u304c\u3093\u7d30\u80de\u304c\u5168\u8eab\u306b\u5e83\u304c\u308b\u5834\u5408\u304c\u3042\u308b\u3068\u3044\u3046\u4eee\u8aac\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3068\u306f\u3044\u3048\u3001\u91cd\u8981\u306a\u4e8b\u5b9f\u3068\u3057\u3066\u3001\u624b\u8853\u524d\u306e\u6642\u70b9\u3067\u305d\u306e\u816b\u760d\u306f\u3059\u3067\u306b\u60aa\u6027\u3067\u3042\u3063\u305f\u3068\u3044\u3046\u70b9\u306b\u5909\u308f\u308a\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3064\u307e\u308a\u3001\u624b\u8853\u304c\u304c\u3093\u306e\u539f\u56e0\u3068\u306a\u3063\u305f\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u3059\u3067\u306b\u304c\u3093\u3060\u3063\u305f\u3082\u306e\u304c\u3001\u305d\u306e\u5f8c\u306b\u9032\u884c\u3057\u305f\u3060\u3051\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u826f\u6027\u306e\u6bcd\u6591\uff08benign nevus\uff09\u3092\u5207\u9664\u3059\u308b\u3053\u3068\u3067\u304c\u3093\u304c\u767a\u751f\u3057\u305f\u308a\u3001\u60aa\u5316\u3059\u308b\u3053\u3068\u306f\u306a\u3044\u3068\u7d50\u8ad6\u3065\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"480\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/24113206_s.jpg\" alt=\"\u65e5\u5098\" class=\"wp-image-4527\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/24113206_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/24113206_s-300x225.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u307b\u304f\u308d\u3092\u50b7\u3064\u3051\u308b\u3068\u304c\u3093\u306b\u306a\u308b\u306e\u304b\uff1f<\/h2>\n\n\n\n<p>\u300c\u307b\u304f\u308d\u3092\u3072\u3063\u304b\u3044\u305f\u308a\u3001\u30ab\u30df\u30bd\u30ea\u3067\u50b7\u3064\u3051\u305f\u308a\u3059\u308b\u3068\u304c\u3093\u306b\u306a\u308b\u306e\u3067\u306f\uff1f\u300d\u3068\u3044\u3046\u4e0d\u5b89\u3082\u975e\u5e38\u306b\u591a\u304f\u805e\u304b\u308c\u307e\u3059\u3002\u30a2\u30f3\u30b1\u30fc\u30c8\u3067\u306f\u300132\uff05\u306e\u5973\u6027\u304c\u300c\u307b\u304f\u308d\u306e\u5916\u50b7\u306f\u5fc3\u914d\u3060\u300d\u3068\u56de\u7b54\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u305f\u3057\u304b\u306b\u3001\u5916\u50b7\u306b\u3088\u3063\u3066\u307b\u304f\u308d\u304c\u8d64\u304f\u306a\u3063\u305f\u308a\u3001\u51fa\u8840\u3057\u305f\u308a\u3001\u5f62\u304c\u5909\u308f\u308b\u3068\u3001\u60a3\u8005\u306f\u4e0d\u5b89\u306b\u306a\u308a\u307e\u3059\u3057\u3001\u533b\u5e2b\u306b\u3068\u3063\u3066\u3082\u8a3a\u65ad\u304c\u96e3\u3057\u304f\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3068\u304f\u306b\u300c\u518d\u767a\u6bcd\u6591\uff08recurrent nevus\uff09\u300d\u306f\u3001\u5916\u50b7\u3084\u4e0d\u5b8c\u5168\u306a\u5207\u9664\u5f8c\u306b\u518d\u3073\u51fa\u73fe\u3059\u308b\u6bcd\u6591\u3067\u3042\u308a\u3001\u5916\u898b\u3084\u7d44\u7e54\u5b66\u7684\u306b\u30e1\u30e9\u30ce\u30fc\u30de\u3068\u533a\u5225\u304c\u3064\u304d\u306b\u304f\u3044\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6b74\u53f2\u7684\u306b\u306f\u30011913\u5e74\u306bGaskill\u533b\u5e2b\u304c\u300c\u4e0d\u5feb\u306a\u9774\u306b\u3088\u308b\u8db3\u88cf\u306e\u5727\u8feb\u304c\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u539f\u56e0\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u300d\u3068\u5831\u544a\u3057\u307e\u3057\u305f\u304c\u3001\u305d\u306e\u5f8c\u306e\u79d1\u5b66\u7684\u7814\u7a76\u306f\u3053\u306e\u4eee\u8aac\u3092\u5426\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002\u30cf\u30e0\u30b9\u30bf\u30fc\u3084\u9b5a\u985e\u306e\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u5b9f\u9a13\u3001\u307e\u305f\u4eba\u9593\u306e\u5927\u898f\u6a21\u8abf\u67fb\u306b\u304a\u3044\u3066\u3082\u3001\u300c\u5916\u50b7\u306b\u3088\u3063\u3066\u307b\u304f\u308d\u304c\u304c\u3093\u5316\u3057\u305f\u300d\u3068\u3059\u308b\u8a3c\u62e0\u306f\u898b\u3064\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u4f8b\u5916\u7684\u306b\u3001\u722a\u306e\u4e0b\u306b\u3067\u304d\u308b\u7279\u6b8a\u306a\u30e1\u30e9\u30ce\u30fc\u30de\uff08nail apparatus melanoma\uff1aNAM\uff09\u3067\u306f\u3001\u5916\u50b7\u304c\u4e88\u5f8c\uff08prognosis\uff09\u306b\u60aa\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002Bormann\u3089\u306e\u7814\u7a76\u3067\u306f\u3001\u816b\u760d\u90e8\u4f4d\u3078\u306e\u5916\u50b7\u304c\u6b7b\u4ea1\u30ea\u30b9\u30af\u3092\u7d045\u500d\u306b\u9ad8\u3081\u308b\u3068\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002\u3068\u306f\u3044\u3048\u3001\u3053\u308c\u3082\u5916\u50b7\u304c\u300c\u304c\u3093\u3092\u5f15\u304d\u8d77\u3053\u3059\u300d\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u300c\u3059\u3067\u306b\u5b58\u5728\u3057\u3066\u3044\u305f\u304c\u3093\u3092\u60aa\u5316\u3055\u305b\u305f\u300d\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7d50\u8ad6\u3068\u3057\u3066\u306f\u3001\u300c\u307b\u304f\u308d\u3092\u50b7\u3064\u3051\u305f\u304b\u3089\u3068\u3044\u3063\u3066\u3001\u305d\u308c\u304c\u76f4\u63a5\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u539f\u56e0\u306b\u306a\u308b\u3053\u3068\u306f\u306a\u3044\u300d\u3068\u8a00\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"427\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/22368429_s.jpg\" alt=\"\u307b\u304f\u308d\" class=\"wp-image-4529\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/22368429_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/22368429_s-300x200.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u8db3\u306e\u88cf\u306e\u307b\u304f\u308d\u306f\u7279\u306b\u5371\u967a\u306a\u306e\u304b\uff1f<\/h2>\n\n\n\n<p>\u591a\u304f\u306e\u4eba\u304c\u300c\u8db3\u306e\u88cf\u3084\u624b\u306e\u3072\u3089\u306e\u307b\u304f\u308d\u306f\u7279\u306b\u60aa\u6027\u5316\u3057\u3084\u3059\u3044\u300d\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u30a2\u30f3\u30b1\u30fc\u30c8\u3067\u308220\uff05\u306e\u5973\u6027\u304c\u3001\u6700\u3082\u4e0d\u5b89\u306a\u90e8\u4f4d\u3068\u3057\u3066\u300c\u624b\u3084\u8db3\u300d\u3092\u6319\u3052\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u8003\u3048\u65b9\u306f\u3001\u304b\u3064\u3066\u5e83\u304f\u4fe1\u3058\u3089\u308c\u3066\u3044\u305f\u300c\u624b\u306e\u3072\u3089\u3084\u8db3\u306e\u88cf\u306e\u307b\u304f\u308d\u306f\u4e88\u9632\u7684\u306b\u5207\u9664\u3059\u3079\u304d\u3060\u300d\u3068\u3044\u3046\u533b\u7642\u65b9\u91dd\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u65b9\u91dd\u306e\u6839\u62e0\u3067\u3042\u3063\u305f2\u3064\u306e\u524d\u63d0\u2015\u2015(1) \u30e1\u30e9\u30ce\u30fc\u30de\u306f\u65e2\u5b58\u306e\u307b\u304f\u308d\u304b\u3089\u767a\u751f\u3059\u308b\u3001(2) \u6469\u64e6\u306a\u3069\u306e\u5916\u50b7\u304c\u539f\u56e0\u306b\u306a\u308b\u2015\u2015\u306f\u3001\u3069\u3061\u3089\u3082\u8fd1\u5e74\u5426\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<p>1960\u5e74\u3001Wilson\u3089\u306f\u3001\u8db3\u5e95\u90e8\u306e\u307b\u304f\u308d\u306e\u983b\u5ea6\u3068\u3001\u305d\u3053\u306b\u767a\u751f\u3059\u308b\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u983b\u5ea6\u306b\u9006\u76f8\u95a2\u304c\u3042\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001Nagore\u3089\u306e\u5927\u898f\u6a21\u7814\u7a76\u3067\u306f\u3001\u307b\u304b\u306e\u30e1\u30e9\u30ce\u30fc\u30de\u3068\u6bd4\u3079\u3066\u3001\u8db3\u88cf\u306b\u3067\u304d\u308b\u30a2\u30af\u30ed\u30fc\u578b\u30e1\u30e9\u30ce\u30fc\u30de\uff08acral melanoma\uff09\u306f\u3001\u307b\u304f\u308d\u304b\u3089\u767a\u751f\u3059\u308b\u5272\u5408\u304c\u975e\u5e38\u306b\u4f4e\u3044\uff088.3\uff05\uff09\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u52a0\u3048\u3066\u3001\u907a\u4f1d\u5b50\u7684\u306b\u3082\u30a2\u30af\u30ed\u30fc\u578b\u306fBRAF\u907a\u4f1d\u5b50\u5909\u7570\uff08BRAF mutation\uff09\u306e\u983b\u5ea6\u304c\u4f4e\u304f\u3001\u4ed6\u306e\u30bf\u30a4\u30d7\u306e\u30e1\u30e9\u30ce\u30fc\u30de\u3068\u306f\u767a\u751f\u6a5f\u5e8f\u304c\u7570\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u8db3\u306e\u88cf\u306e\u307b\u304f\u308d\u304c\u7279\u5225\u306b\u5371\u967a\u3067\u3042\u308b\u3068\u3044\u3046\u79d1\u5b66\u7684\u6839\u62e0\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u9069\u5207\u306a\u89b3\u5bdf\u304c\u63a8\u5968\u3055\u308c\u308b\u3060\u3051\u3067\u3001\u4e88\u9632\u7684\u306b\u5207\u9664\u3059\u308b\u5fc5\u8981\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"299\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/27098795_s.jpg\" alt=\"\u8db3\" class=\"wp-image-4530\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/27098795_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/27098795_s-300x140.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u307b\u304f\u308d\u306b\u3060\u3051\u65e5\u713c\u3051\u6b62\u3081\u3092\u5857\u308c\u3070\u826f\u3044\u306e\u304b\uff1f<\/h2>\n\n\n\n<p>\u7d2b\u5916\u7dda\uff08ultraviolet radiation\uff1aUVR\uff09\u304c\u76ae\u819a\u304c\u3093\u306e\u30ea\u30b9\u30af\u8981\u56e0\u3067\u3042\u308b\u3053\u3068\u306f\u5e83\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u77e5\u8b58\u304c\u8aa4\u3063\u305f\u884c\u52d5\u306b\u7e4b\u304c\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u4e00\u4f8b\u304c\u3001\u300c\u307b\u304f\u308d\u306e\u90e8\u5206\u3060\u3051\u306b\u65e5\u713c\u3051\u6b62\u3081\u3092\u5857\u308b\u300d\u3068\u3044\u3046\u7fd2\u6163\u3067\u3059\u3002\u30a2\u30f3\u30b1\u30fc\u30c8\u3067\u306f11\uff05\u306e\u5973\u6027\u304c\u3001\u3053\u306e\u3088\u3046\u306a\u300c\u9078\u629e\u7684\u306a\u5857\u5e03\uff08selective sunscreen application\uff09\u300d\u3092\u3057\u3066\u3044\u308b\u3068\u56de\u7b54\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u300c\u7d2b\u5916\u7dda\u306b\u3088\u3063\u3066\u307b\u304f\u308d\u304c\u304c\u3093\u5316\u3059\u308b\u300d\u3068\u8aa4\u89e3\u3057\u3066\u3044\u308b\u305f\u3081\u3067\u3059\u304c\u3001\u5b9f\u969b\u306b\u306f\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u5927\u534a\uff08\u7d0470\uff5e90\uff05\uff09\u306f\u3001\u65e2\u5b58\u306e\u307b\u304f\u308d\u304b\u3089\u3067\u306f\u306a\u304f\u3001\u6b63\u5e38\u306a\u76ae\u819a\u304b\u3089\u65b0\u305f\u306b\uff08de novo\uff09\u767a\u751f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001Zhao\u3089\u306e\u7814\u7a76\u3067\u306f\u3001\u7d2b\u5916\u7dda\u306b\u3088\u3063\u3066DNA\u640d\u50b7\uff08UV-induced photoproducts\uff09\u304c\u8d77\u3053\u308b\u90e8\u4f4d\u306f\u3001\u307b\u304f\u308d\u3088\u308a\u3082\u5468\u56f2\u306e\u6b63\u5e38\u76ae\u819a\u306e\u307b\u3046\u304c3\uff5e5\u500d\u591a\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3064\u307e\u308a\u3001\u307b\u304f\u308d\u3060\u3051\u306b\u65e5\u713c\u3051\u6b62\u3081\u3092\u5857\u3063\u3066\u3082\u3001\u76ae\u819a\u304c\u3093\u4e88\u9632\u306b\u306f\u306a\u308a\u307e\u305b\u3093\u3002\u9854\u3084\u8155\u306a\u3069\u9732\u51fa\u3059\u308b\u90e8\u4f4d\u3059\u3079\u3066\u306b\u3001\u9069\u5207\u306a\u91cf\u3068\u983b\u5ea6\u3067\u65e5\u713c\u3051\u6b62\u3081\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"427\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/24217612_s.jpg\" alt=\"\u5857\u308a\u307e\u3059\" class=\"wp-image-4531\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/24217612_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/24217612_s-300x200.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u8a3a\u65ad\u3067\u90e8\u5206\u7684\u306a\u751f\u691c\u306f\u5371\u967a\u306a\u306e\u304b\uff1f<\/h2>\n\n\n\n<p>\u76ae\u819a\u75c5\u5909\u306e\u4e00\u90e8\u3060\u3051\u3092\u5207\u308a\u53d6\u3063\u3066\u884c\u3046\u90e8\u5206\u751f\u691c\uff08partial biopsy\uff09\u306f\u3001\u300c\u304c\u3093\u7d30\u80de\u3092\u523a\u6fc0\u3057\u3066\u8ee2\u79fb\u3092\u4fc3\u3059\u300d\u3068\u4fe1\u3058\u308b\u4eba\u3082\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3053\u306e\u8003\u3048\u65b9\u306f\u3001\u8907\u6570\u306e\u5927\u898f\u6a21\u7814\u7a76\u306b\u3088\u3063\u3066\u5426\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30e1\u30e9\u30ce\u30fc\u30de\u304c\u7591\u308f\u308c\u308b\u5834\u5408\u3001\u7406\u60f3\u7684\u306b\u306f\u75c5\u5909\u5168\u4f53\u3092\u5207\u9664\u3057\u3066\u8abf\u3079\u308b\u300c\u5168\u5207\u9664\u751f\u691c\uff08excisional biopsy\uff09\u300d\u304c\u671b\u307e\u3057\u3044\u3067\u3059\u304c\u3001\u9854\u3084\u722a\u306e\u4e0b\u306a\u3069\u306e\u90e8\u4f4d\u3067\u306f\u90e8\u5206\u751f\u691c\u304c\u73fe\u5b9f\u7684\u306a\u9078\u629e\u80a2\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<p>\u904e\u53bb\u306b\u306f\u3001\u90e8\u5206\u751f\u691c\u304c\u4e88\u5f8c\u306b\u60aa\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3068\u3059\u308b\u5831\u544a\u3082\u3042\u308a\u307e\u3057\u305f\u304c\u3001\u305d\u308c\u3089\u306f\u816b\u760d\u306e\u539a\u307f\uff08Breslow thickness\uff09\u3068\u3044\u3046\u6700\u91cd\u8981\u56e0\u5b50\u304c\u672a\u8a55\u4fa1\u3067\u3042\u3063\u305f\u70b9\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u30022005\u5e74\u306e2,164\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7121\u4f5c\u70ba\u5316\u524d\u5411\u304d\u7814\u7a76\u3067\u306f\u3001\u90e8\u5206\u751f\u691c\u3001\u30b7\u30a7\u30fc\u30d3\u30f3\u30b0\u751f\u691c\u3001\u5168\u5207\u9664\u751f\u691c\u306e\u9593\u3067\u3001\u518d\u767a\u7387\u3084\u751f\u5b58\u7387\u306b\u6709\u610f\u306a\u5dee\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u90e8\u5206\u751f\u691c\u304c\u8a3a\u65ad\u306b\u591a\u5c11\u306e\u5236\u7d04\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u304c\u76f4\u63a5\u60a3\u8005\u306e\u751f\u5b58\u306b\u60aa\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3068\u3044\u3046\u8a3c\u62e0\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"427\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/31917897_s.jpg\" alt=\"\u76ae\u819a\" class=\"wp-image-4446\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/31917897_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/31917897_s-300x200.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u307b\u304f\u308d\u306f\u30e1\u30e9\u30ce\u30fc\u30de\u306b\u5909\u308f\u308b\u306e\u304b\uff1f<\/h2>\n\n\n\n<p>\u300c\u307b\u304f\u308d\u306f\u304c\u3093\u5316\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u300d\u3068\u3088\u304f\u8a00\u308f\u308c\u307e\u3059\u304c\u3001\u5b9f\u969b\u306b\u306f\u3001\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u591a\u304f\u306f\u6b63\u5e38\u306a\u76ae\u819a\u304b\u3089\u76f4\u63a5\u767a\u751f\u3057\u3001\u65e2\u5b58\u306e\u307b\u304f\u308d\u304b\u3089\u767a\u751f\u3059\u308b\u306e\u306f10\uff5e30\uff05\u7a0b\u5ea6\u306b\u3059\u304e\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u300c\u7570\u578b\u6bcd\u6591\uff08dysplastic nevus\uff09\u300d\u3068\u3044\u3046\u8a3a\u65ad\u540d\u306f\u3001\u304b\u3064\u3066\u306f\u524d\u304c\u3093\u75c5\u5909\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u73fe\u5728\u3067\u306f\u3053\u308c\u306f\u826f\u6027\u306e\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u3067\u3042\u308a\u3001\u304c\u3093\u5316\u30ea\u30b9\u30af\u306f\u4ed6\u306e\u6bcd\u6591\u3068\u540c\u69d8\u306b\u975e\u5e38\u306b\u4f4e\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u500b\u3005\u306e\u307b\u304f\u308d\u304c\u30e1\u30e9\u30ce\u30fc\u30de\u306b\u5909\u308f\u308b\u78ba\u7387\u306f\u300120\u6b73\u7537\u6027\u3067\u751f\u6daf1\/3,164\u3001\u5973\u6027\u30671\/10,800\u3068\u6975\u3081\u3066\u4f4e\u304f\u3001\u307b\u304f\u308d\u304c\u591a\u3044\u4eba\u306f\u300c\u307b\u304f\u308d\u304c\u304c\u3093\u306b\u306a\u308b\u304b\u3089\u300d\u3067\u306f\u306a\u304f\u3001\u300c\u30e1\u30e9\u30ce\u30fc\u30de\u306e\u30ea\u30b9\u30af\u5168\u4f53\u304c\u9ad8\u3044\u300d\u304b\u3089\u6ce8\u610f\u304c\u5fc5\u8981\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u3059\u3079\u3066\u306e\u307b\u304f\u308d\u3092\u300c\u4e88\u9632\u7684\u306b\u300d\u5207\u9664\u3059\u308b\u3068\u3044\u3046\u8003\u3048\u306f\u8aa4\u308a\u3067\u3042\u308a\u3001\u904e\u5270\u306a\u51e6\u7f6e\u3084\u533b\u7642\u8cc7\u6e90\u306e\u7121\u99c4\u9063\u3044\u306b\u7e4b\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"427\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/24446901_s.jpg\" alt=\"\u3072\u304c\u3055\" class=\"wp-image-4532\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/24446901_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/24446901_s-300x200.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u8584\u3044\u30e1\u30e9\u30ce\u30fc\u30de\u3084\u30b9\u30d4\u30c3\u30c4\u6bcd\u6591\u306b\u30bb\u30f3\u30c1\u30cd\u30eb\u30ea\u30f3\u30d1\u7bc0\u751f\u691c\u306f\u5fc5\u8981\u304b\uff1f<\/h2>\n\n\n\n<p>\u30bb\u30f3\u30c1\u30cd\u30eb\u30ea\u30f3\u30d1\u7bc0\u751f\u691c\uff08sentinel lymph node biopsy\uff1aSLNB\uff09\u306f\u3001\u304c\u3093\u304c\u6700\u521d\u306b\u8ee2\u79fb\u3059\u308b\u30ea\u30f3\u30d1\u7bc0\u3092\u7279\u5b9a\u3057\u3001\u75c5\u671f\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306e\u4f4e\u4fb5\u8972\u7684\u306a\u624b\u8853\u3067\u3059\u3002\u30e1\u30e9\u30ce\u30fc\u30de\u3067\u3082\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u8584\u3044\u816b\u760d\uff08Breslow\u539a1 mm\u4ee5\u4e0b\uff09\u3084\u3001\u7279\u6b8a\u306a\u30b9\u30d4\u30c3\u30c4\u6bcd\u6591\uff08atypical Spitz tumor\uff1aAST\uff09\u306b\u5bfe\u3057\u3066\u306f\u8b70\u8ad6\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>NCCN\uff08National Comprehensive Cancer Network\uff09\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3001\u30e1\u30e9\u30ce\u30fc\u30de\u304c0.75 mm\u4ee5\u4e0b\u3067\u6f70\u760d\u304c\u306a\u304f\u3001\u7d30\u80de\u5206\u88c2\uff08mitotic rate\uff09\u304c\u30bc\u30ed\u306e\u5834\u5408\u3001SLNB\u306f\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u30ea\u30b9\u30af\u56e0\u5b50\u304c\u3042\u308b\u5834\u5408\u3084\u8a3a\u65ad\u304c\u4e0d\u78ba\u304b\u306a\u5834\u5408\u306b\u306f\u3001\u60a3\u8005\u3068\u533b\u5e2b\u304c\u76f8\u8ac7\u3057\u3066\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"427\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/3637104_s.jpg\" alt=\"\u65e5\u713c\u3051\u907f\u3051\" class=\"wp-image-4534\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/3637104_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/3637104_s-300x200.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>AST\u306b\u304a\u3044\u3066\u306f\u3001Lallas\u3089\u306b\u3088\u308b\u30ec\u30d3\u30e5\u30fc\u3067\u3001SLNB\u306e\u4e88\u5f8c\u7684\u30fb\u8a3a\u65ad\u7684\u4fa1\u5024\u306f\u4e4f\u3057\u3044\u3068\u7d50\u8ad6\u3065\u3051\u3089\u308c\u307e\u3057\u305f\u3002\u305f\u3068\u3048SLNB\u967d\u6027\u3067\u3042\u3063\u3066\u3082\u3001AST\u60a3\u8005\u306e5\u5e74\u751f\u5b58\u7387\u306f99\uff05\u3068\u975e\u5e38\u306b\u9ad8\u304f\u3001\u624b\u8853\u306e\u610f\u7fa9\u304c\u4e4f\u3057\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u3001SLNB\u306f\u300c\u6cbb\u7642\u300d\u3067\u306f\u306a\u304f\u3001\u3042\u304f\u307e\u3067\u300c\u75c5\u671f\u306e\u8a55\u4fa1\u300d\u3068\u3057\u3066\u4f4d\u7f6e\u3065\u3051\u308b\u3079\u304d\u3067\u3042\u308a\u3001\u5b89\u6613\u306b\u5b9f\u65bd\u3059\u3079\u304d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"427\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/22066461_s.jpg\" alt=\"\u5207\u308a\u306b\u884c\u304d\u307e\u3059\" class=\"wp-image-4478\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/22066461_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/22066461_s-300x200.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><figure><a href=\"\/dermatology\/access\/\"><br \/>\n<img decoding=\"async\" src=\"\/dermatology\/wp-content\/uploads\/2025\/04\/cta-pattern1.webp\" alt=\"\u8eab\u8fd1\u306a\u76ae\u819a\u306e\u60a9\u307f\u3001\u5c02\u9580\u533b\u306b\u6c17\u8efd\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002\u30af\u30ea\u30cb\u30c3\u30af\u306f\u3053\u3061\u3089\" \/><br \/>\n<\/a><\/figure>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u7d50\u8ad6<\/h2>\n\n\n\n<p>\u76ae\u819a\u306e\u8272\u7d20\u6027\u75c5\u5909\u306b\u95a2\u3059\u308b\u8aa4\u89e3\u306f\u3001\u4e16\u754c\u4e2d\u306e\u76ae\u819a\u79d1\u8a3a\u7642\u306b\u5e83\u304f\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u795e\u8a71\u306f\u3001\u30e1\u30c7\u30a3\u30a2\u3001\u6559\u80b2\u3001\u6642\u306b\u306f\u533b\u7642\u8005\u81ea\u8eab\u306b\u3088\u3063\u3066\u3082\u518d\u751f\u7523\u3055\u308c\u3066\u304a\u308a\u3001\u60a3\u8005\u306e\u4e0d\u5b89\u3084\u4e0d\u9069\u5207\u306a\u51e6\u7f6e\u3092\u62db\u304f\u539f\u56e0\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u3044\u305f\u6279\u5224\u7684\u601d\u8003\u3092\u80b2\u3066\u308b\u3053\u3068\u3067\u3001\u3053\u3046\u3057\u305f\u8aa4\u89e3\u3092\u6e1b\u3089\u3057\u3001\u3088\u308a\u5b89\u5168\u3067\u5408\u7406\u7684\u306a\u533b\u7642\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u533b\u7642\u95a2\u4fc2\u8005\u304c\u3001\u51fa\u6240\u306b\u304b\u304b\u308f\u3089\u305a\u3001\u6839\u62e0\u306e\u306a\u3044\u4eee\u8aac\u3092\u691c\u8a3c\u3057\u7d9a\u3051\u308b\u59ff\u52e2\u3092\u6301\u3064\u3053\u3068\u304c\u3001\u60a3\u8005\u306e\u5229\u76ca\u306b\u7e4b\u304c\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<div 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