{"id":5267,"date":"2025-09-09T13:01:59","date_gmt":"2025-09-09T04:01:59","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/dermatology\/?p=5267"},"modified":"2025-09-09T13:01:59","modified_gmt":"2025-09-09T04:01:59","slug":"malignant-melanoma-stage-treatment","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/dermatology\/derma\/dermatology-basics\/skin-disease-guide\/malignant-melanoma-stage-treatment\/","title":{"rendered":"\u60aa\u6027\u9ed2\u8272\u816b\u306e\u9032\u884c\u5ea6\u3068\u6cbb\u7642\u6cd5"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<p>\u60aa\u6027\u9ed2\u8272\u816b\uff08\u30e1\u30e9\u30ce\u30fc\u30de\uff09\u306f\u816b\u760d\u306e\u539a\u3055\u3084\u8ee2\u79fb\u306e\u6709\u7121\u306b\u3088\u308a\u30b9\u30c6\u30fc\u30b8\u5206\u985e\u3055\u308c\u3001\u305d\u306e\u9032\u884c\u5ea6\u306b\u5fdc\u3058\u305f\u6cbb\u7642\u6cd5\u3092\u65e9\u671f\u306b\u9078\u629e\u3059\u308b\u3053\u3068\u304c\u6cbb\u7642\u6210\u7e3e\u306b\u76f4\u7d50\u3057\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u6700\u65b0\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3084\u5c02\u9580\u7684\u77e5\u898b\u306b\u57fa\u3065\u304d\u3001\u30b9\u30c6\u30fc\u30b8\u3054\u3068\u306e\u5177\u4f53\u7684\u306a\u9032\u884c\u5ea6\u3068\u6cbb\u7642\u6226\u7565\u3001\u6700\u65b0\u306e\u85ac\u7269\u7642\u6cd5\u30fb\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5\u307e\u3067\u3092\u7db2\u7f85\u7684\u306b\u89e3\u8aac\u3057\u307e\u3059\u3002\u65e9\u671f\u6cbb\u7642\u306e\u610f\u7fa9\u3084\u9078\u629e\u80a2\u3001\u5404\u6cbb\u7642\u6cd5\u306e\u7279\u5fb4\u306b\u3064\u3044\u3066\u6df1\u304f\u7406\u89e3\u3057\u305f\u3044\u65b9\u306b\u5411\u3051\u305f\u5c02\u9580\u6027\u306e\u9ad8\u3044\u5185\u5bb9\u3067\u3059\u3002<br><\/p>\n\n\n\n<h2 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class=\"has-fixed-layout\"><tbody><tr><td><strong>\u30b9\u30c6\u30fc\u30b8<\/strong><\/td><td><strong>\u7279\u5fb4<\/strong><\/td><\/tr><tr><td>0\u671f\uff08\u4e0a\u76ae\u5185\u304c\u3093\uff09<\/td><td>\u304c\u3093\u304c\u8868\u76ae\u5185\u306b\u3068\u3069\u307e\u308b\u975e\u5e38\u306b\u521d\u671f\u306e\u72b6\u614b<\/td><\/tr><tr><td>\u2160\u671f<\/td><td>\u816b\u760d\u306e\u539a\u3055\u304c1\u301c2\u202fmm\u4ee5\u4e0b\u3001\u8ee2\u79fb\u306a\u3057\u3002\u2160A\/B\u306b\u7d30\u5206\u3082\u5b58\u5728<\/td><\/tr><tr><td>\u2161\u671f<\/td><td>\u8ee2\u79fb\u306a\u3057\u3060\u304c\u539a\u30552\u301c4\u202fmm\u4ee5\u4e0a\u3001\u6f70\u760d\u306e\u6709\u7121\u3067\u2161A\/B\/C\u306b\u5206\u985e<\/td><\/tr><tr><td>\u2162\u671f<\/td><td>\u30ea\u30f3\u30d1\u7bc0\u307e\u305f\u306f\u76ae\u819a\u8ee2\u79fb\u3042\u308a\uff08\u539a\u3055\u30fb\u6f70\u760d\u95a2\u4fc2\u306a\u3057\uff09<\/td><\/tr><tr><td>\u2163\u671f<\/td><td>\u80ba\u30fb\u809d\u30fb\u8133\u306a\u3069\u4ed6\u81d3\u5668\u3078\u306e\u9060\u9694\u8ee2\u79fb\u3042\u308a<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u9032\u884c\u5ea6\u304c\u9032\u3080\u307b\u3069\u4e88\u5f8c\u306f\u60aa\u5316\u3057\u3001\u4f8b\u3048\u30705\u5e74\u751f\u5b58\u7387\u306f\u2160\u671f\u3067\u7d0480\u301c90%\u3001\u2161\u671f\u306780\uff05\u524d\u5f8c\u3001\u2162\u671f\u306750%\u524d\u5f8c\u3001\u2163\u671f\u3067\u306f10\u301c11%\u3068\u4f4e\u4e0b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30b9\u30c6\u30fc\u30b8\u5225\u306e\u57fa\u672c\u7684\u6cbb\u7642\u6226\u7565<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b9\u30c6\u30fc\u30b80\u301c\u2161\u671f\uff1a\u624b\u8853\u304c\u57fa\u672c\u306e\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<ul 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class=\"wp-block-list\">\n<li>\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\uff08\u5358\u5264\u30fb\u4f75\u7528\uff09\u306e\u767b\u5834\u306b\u3088\u308a\u3001\u5207\u9664\u4e0d\u80fd\u306a\u9032\u884c\u4f8b\u3067\u3082\u9577\u671f\u751f\u5b58\u304c\u671f\u5f85\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<br><\/li>\n\n\n\n<li>\u5206\u5b50\u6a19\u7684\u85ac\u306b\u3088\u308b\u8fc5\u901f\u306a\u816b\u760d\u7e2e\u5c0f\u306e\u671f\u5f85\u3082\u3042\u308a\u3001\u7279\u306bBRAF\u5909\u7570\u967d\u6027\u4f8b\u3067\u306f\u91cd\u8981\u306a\u6226\u7565\u3067\u3059\u3002<br><\/li>\n\n\n\n<li>\u5316\u5b66\u7642\u6cd5\u306f\u88dc\u52a9\u7684\u306a\u5f79\u5272\u306b\u7559\u307e\u308a\u307e\u3059\u304c\u3001\u514d\u75ab\u30fb\u5206\u5b50\u6a19\u7684\u7642\u6cd5\u304c\u4f7f\u3048\u306a\u3044\u5834\u5408\u306e\u9078\u629e\u80a2\u306b\u306a\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u653e\u5c04\u7dda\u306e\u6280\u8853\u9032\u6b69\u306b\u3088\u308a\u3001\u8133\u8ee2\u79fb\u306b\u5bfe\u3059\u308b\u5b9a\u4f4d\u653e\u5c04\u7dda\u6cbb\u7642\uff08\u30ac\u30f3\u30de\u30ca\u30a4\u30d5\u7b49\uff09\u3084\u91cd\u7c92\u5b50\u7dda\u6cbb\u7642\u306a\u3069\u3001\u65b0\u3057\u3044\u6cbb\u7642\u624b\u6bb5\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u6cbb\u7642\u9078\u629e\u306b\u304a\u3051\u308b\u30dd\u30a4\u30f3\u30c8\u3068\u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u500b\u5225\u5316\u533b\u7642\u306e\u91cd\u8981\u6027<\/strong>\uff1aBRAF\u5909\u7570\u306e\u6709\u7121\u3001\u60a3\u8005\u306e\u5168\u8eab\u72b6\u614b\uff08\u5e74\u9f62\u30fb\u5408\u4f75\u75c7\u306a\u3069\uff09\u3092\u8e0f\u307e\u3048\u3001\u514d\u75ab\u7642\u6cd5\uff0f\u5206\u5b50\u7642\u6cd5\uff0f\u624b\u8853\u306e\u9806\u5e8f\u3084\u4f75\u7528\u3092\u691c\u8a0e\u3002<br><\/li>\n\n\n\n<li><strong>\u526f\u4f5c\u7528\u7ba1\u7406\u306e\u5fb9\u5e95<\/strong>\uff1a\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\u306f\u6709\u5bb3\u4e8b\u8c61\uff08\u76ae\u75b9\u3001\u809d\u30fb\u5185\u5206\u6ccc\u969c\u5bb3\u306a\u3069\uff09\u304c\u61f8\u5ff5\u3055\u308c\u3001\u7d99\u7d9a\u7684\u306a\u691c\u67fb\u3068\u5bfe\u5fdc\u304c\u5fc5\u8981\u3067\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u9577\u671f\u7d4c\u904e\u89b3\u5bdf\u306e\u91cd\u8981\u6027<\/strong>\uff1a\u65e9\u671f\u3067\u3082\u518d\u767a\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u5b9a\u671f\u7684\u306a\u753b\u50cf\u691c\u67fb\u3084\u8a3a\u5bdf\u306b\u3088\u308b\u30d5\u30a9\u30ed\u30fc\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u60aa\u6027\u9ed2\u8272\u816b\u306e\u65e9\u671f\u767a\u898b\u3068\u8a3a\u65ad\u65b9\u6cd5<\/strong><\/h2>\n\n\n\n<p>\u60aa\u6027\u9ed2\u8272\u816b\u306f\u3001<strong>\u65e9\u671f\u306b\u767a\u898b\u3057\u5207\u9664\u3059\u308b\u3053\u3068\u3067\u5b8c\u6cbb\u304c\u671f\u5f85\u3067\u304d\u308b\u76ae\u819a\u304c\u3093<\/strong>\u306e\u4e00\u3064\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u30bb\u30eb\u30d5\u30c1\u30a7\u30c3\u30af\u3084\u5b9a\u671f\u7684\u306a\u76ae\u819a\u79d1\u53d7\u8a3a\u304c\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>ABCDE\u30eb\u30fc\u30eb\u306b\u3088\u308b\u30bb\u30eb\u30d5\u30c1\u30a7\u30c3\u30af<\/strong><\/h3>\n\n\n\n<p>\u7c73\u56fd\u76ae\u819a\u79d1\u5b66\u4f1a\uff08AAD\uff09\u306a\u3069\u304c\u63a8\u5968\u3059\u308b\u300cABCDE\u30eb\u30fc\u30eb\u300d\u306f\u3001\u76ae\u819a\u306e\u7570\u5e38\u3092\u81ea\u5df1\u5224\u65ad\u3059\u308b\u969b\u306e\u6709\u7528\u306a\u6307\u6a19\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>\u9805\u76ee<\/strong><\/td><td><strong>\u8aac\u660e<\/strong><\/td><\/tr><tr><td>A\uff08Asymmetry\uff09<\/td><td>\u5de6\u53f3\u975e\u5bfe\u79f0\u306e\u5f62\u72b6<\/td><\/tr><tr><td>B\uff08Border\uff09<\/td><td>\u5883\u754c\u304c\u30ae\u30b6\u30ae\u30b6\u3001\u4e0d\u898f\u5247<\/td><\/tr><tr><td>C\uff08Color\uff09<\/td><td>\u8272\u304c\u5747\u4e00\u3067\u306a\u3044\uff08\u9ed2\u30fb\u8336\u30fb\u8d64\u30fb\u9752\u306a\u3069\u6df7\u5728\uff09<\/td><\/tr><tr><td>D\uff08Diameter\uff09<\/td><td>\u76f4\u5f846mm\u4ee5\u4e0a<\/td><\/tr><tr><td>E\uff08Evolving\uff09<\/td><td>\u5927\u304d\u3055\u3084\u5f62\u3001\u8272\u304c\u5909\u5316\u3057\u3066\u3044\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u7279\u5fb4\u306e\u3044\u305a\u308c\u304b\u306b\u8a72\u5f53\u3059\u308b<strong>\u307b\u304f\u308d\u3084\u76ae\u819a\u75c5\u5909\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u65e9\u6025\u306a\u76ae\u819a\u79d1\u53d7\u8a3a<\/strong>\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u8a3a\u65ad\u624b\u9806<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c0\u30fc\u30e2\u30b9\u30b3\u30d4\u30fc\uff08\u76ae\u819a\u62e1\u5927\u93e1\uff09<\/strong><strong><br><\/strong> \u3000\u76ae\u819a\u79d1\u533b\u306b\u3088\u308b\u30c0\u30fc\u30e2\u30b9\u30b3\u30d4\u30fc\u691c\u67fb\u3067\u3001\u75c5\u5909\u306e\u8272\u8abf\u3084\u69cb\u9020\u306e\u8a73\u7d30\u306a\u89b3\u5bdf\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u60aa\u6027\u304b\u826f\u6027\u304b\u306e\u9451\u5225\u306b\u9ad8\u3044\u8a3a\u65ad\u7cbe\u5ea6\u3092\u8a87\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u751f\u691c\uff08\u30d0\u30a4\u30aa\u30d7\u30b7\u30fc\uff09<\/strong><strong><br><\/strong> \u3000\u78ba\u5b9a\u8a3a\u65ad\u306b\u306f\u3001\u75c5\u5909\u306e\u4e00\u90e8\u307e\u305f\u306f\u5168\u90e8\u3092\u5207\u9664\u3057\u3066\u9855\u5fae\u93e1\u3067\u8abf\u3079\u308b\u751f\u691c\u304c\u5fc5\u8981\u3067\u3059\u3002\u8fd1\u5e74\u3067\u306f\u3001<strong>\u5b8c\u5168\u5207\u9664\u751f\u691c<\/strong>\u304c\u6a19\u6e96\u3068\u3055\u308c\u3001\u5c40\u6240\u9ebb\u9154\u3067\u65e5\u5e30\u308a\u3067\u3082\u5b9f\u65bd\u53ef\u80fd\u3067\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u753b\u50cf\u8a3a\u65ad\uff08CT\uff0fPET-CT\uff0fMRI\uff09<\/strong><strong><br><\/strong> \u3000\u30ea\u30f3\u30d1\u7bc0\u3084\u9060\u9694\u81d3\u5668\u8ee2\u79fb\u304c\u7591\u308f\u308c\u308b\u5834\u5408\u306b\u306f\u3001\u5168\u8eab\u306e\u753b\u50cf\u691c\u67fb\u304c\u884c\u308f\u308c\u3001\u30b9\u30c6\u30fc\u30b8\u5206\u985e\u306e\u78ba\u5b9a\u306b\u6d3b\u7528\u3055\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"640\" height=\"427\" src=\"\/dermatology\/wp-content\/uploads\/2025\/03\/32044166_s.jpg\" alt=\"\u533b\u8005\" class=\"wp-image-4443\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/32044166_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/dermatology\/wp-content\/uploads\/2025\/03\/32044166_s-300x200.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\"><strong>\u6cbb\u7642\u9078\u629e\u3068\u30bb\u30ab\u30f3\u30c9\u30aa\u30d4\u30cb\u30aa\u30f3\u306e\u91cd\u8981\u6027<\/strong><\/h2>\n\n\n\n<p>\u60aa\u6027\u9ed2\u8272\u816b\u306f\u30b9\u30c6\u30fc\u30b8\u306b\u3088\u3063\u3066\u6cbb\u7642\u304c\u5927\u304d\u304f\u5909\u308f\u308b\u305f\u3081\u3001<strong>\u6cbb\u7642\u65b9\u91dd\u306e\u9078\u629e\u306b\u306f\u5c02\u9580\u533b\u306b\u3088\u308b\u8a55\u4fa1\u3068\u3001\u5341\u5206\u306a\u8aac\u660e\u304c\u4e0d\u53ef\u6b20<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6cbb\u7642\u65b9\u91dd\u306b\u8ff7\u3063\u305f\u3068\u304d\u306e\u9078\u629e\u80a2<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30bb\u30ab\u30f3\u30c9\u30aa\u30d4\u30cb\u30aa\u30f3\u306e\u6d3b\u7528<\/strong><strong><br><\/strong> \u3000\u7279\u306b\u9032\u884c\u671f\u3084\u518d\u767a\u4f8b\u3067\u306f\u3001\u514d\u75ab\u7642\u6cd5\u3084\u5206\u5b50\u6a19\u7684\u7642\u6cd5\u306e\u9069\u5fdc\u5224\u65ad\u304c\u5206\u304b\u308c\u308b\u30b1\u30fc\u30b9\u3082\u3042\u308b\u305f\u3081\u3001\u5927\u5b66\u75c5\u9662\u3084\u304c\u3093\u5c02\u9580\u65bd\u8a2d\u3067\u306e\u30bb\u30ab\u30f3\u30c9\u30aa\u30d4\u30cb\u30aa\u30f3\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u304c\u3093\u8a3a\u7642\u9023\u643a\u62e0\u70b9\u75c5\u9662<\/strong><strong><br><\/strong> \u3000\u5168\u56fd\u306b\u6574\u5099\u3055\u308c\u3066\u3044\u308b\u62e0\u70b9\u75c5\u9662\u3067\u306f\u3001\u76ae\u819a\u79d1\u30fb\u816b\u760d\u5185\u79d1\u30fb\u653e\u5c04\u7dda\u79d1\u306a\u3069\u306e\u5c02\u9580\u30c1\u30fc\u30e0\u306b\u3088\u308b**\u591a\u8077\u7a2e\u9023\u643a\uff08MDT\uff09**\u304c\u53ef\u80fd\u3067\u3042\u308a\u3001\u6700\u9069\u306a\u6cbb\u7642\u9078\u629e\u304c\u884c\u308f\u308c\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u81e8\u5e8a\u8a66\u9a13\uff08\u6cbb\u9a13\uff09\u306e\u9078\u629e<\/strong><strong><br><\/strong> \u3000\u6a19\u6e96\u6cbb\u7642\u304c\u594f\u529f\u3057\u306a\u3044\u5834\u5408\u3001\u65b0\u85ac\u306e\u81e8\u5e8a\u8a66\u9a13\uff08\u6cbb\u9a13\uff09\u306b\u53c2\u52a0\u3059\u308b\u9078\u629e\u80a2\u3082\u5b58\u5728\u3057\u307e\u3059\u3002\u56fd\u5185\u3067\u3082\u3001\u514d\u75ab\u7d30\u80de\u7642\u6cd5\u3084\u30ef\u30af\u30c1\u30f3\u7642\u6cd5\u306a\u3069\u306e\u5148\u9032\u6cbb\u7642\u304c\u7814\u7a76\u6bb5\u968e\u3067\u9032\u884c\u4e2d\u3067\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u60a3\u8005\u3068\u5bb6\u65cf\u304c\u3067\u304d\u308b\u30b5\u30dd\u30fc\u30c8\u3068\u60c5\u5831\u53ce\u96c6<\/strong><\/h2>\n\n\n\n<p>\u60aa\u6027\u9ed2\u8272\u816b\u306e\u6cbb\u7642\u306f\u3001\u9577\u671f\u9593\u306b\u53ca\u3076\u3053\u3068\u3082\u591a\u304f\u3001<strong>\u60a3\u8005\u672c\u4eba\u3060\u3051\u3067\u306a\u304f\u5bb6\u65cf\u306e\u7406\u89e3\u3068\u652f\u63f4\u304c\u91cd\u8981<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u60c5\u5831\u53ce\u96c6\u306e\u4fe1\u983c\u6027\u3068\u6ce8\u610f\u70b9<\/strong><\/h3>\n\n\n\n<ul 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