{"id":1177,"date":"2025-09-22T07:46:49","date_gmt":"2025-09-22T07:46:49","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/diet\/?p=1177"},"modified":"2025-09-22T07:46:50","modified_gmt":"2025-09-22T07:46:50","slug":"mounjaro-iryo-diet-henko","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/diet\/mounjaro-iryo-diet-henko\/","title":{"rendered":"\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u7528\u3044\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u73fe\u5834\u3067\u8d77\u304d\u3066\u3044\u308b\u5909\u5316"},"content":{"rendered":"\n<p>\u8fd1\u5e74\u3001\u80a5\u6e80\u6cbb\u7642\u306e\u73fe\u5834\u306b\u304a\u3044\u3066\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u308b\u306e\u304c\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u300d\u3092\u6d3b\u7528\u3057\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u3067\u3059\u3002\u5f93\u6765\u306e\u98df\u4e8b\u7642\u6cd5\u3084\u904b\u52d5\u7642\u6cd5\u3060\u3051\u3067\u306f\u9054\u6210\u304c\u96e3\u3057\u304b\u3063\u305f\u4f53\u91cd\u7ba1\u7406\u306b\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u304c\u65b0\u305f\u306a\u9078\u629e\u80a2\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002\u672c\u7a3f\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u6a5f\u5e8f\u304b\u3089\u81e8\u5e8a\u73fe\u5834\u3067\u306e\u6d3b\u7528\u4e8b\u4f8b\u3001\u60a3\u8005\u3078\u306e\u5f71\u97ff\u3084\u533b\u7642\u73fe\u5834\u3067\u306e\u5909\u5316\u307e\u3067\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u3044\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u30de\u30f3\u30b8\u30e3\u30ed\u3068\u306f\u4f55\u304b<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001GLP-1\uff08\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9-1\uff09\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u4e00\u7a2e\u3067\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u307e\u3057\u305f\u3002GLP-1\u306f\u8178\u7ba1\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3001\u98df\u5f8c\u306e\u8840\u7cd6\u4e0a\u6607\u3092\u6291\u3048\u308b\u4f5c\u7528\u304c\u3042\u308b\u307b\u304b\u3001\u6e80\u8179\u611f\u3092\u9ad8\u3081\u308b\u50cd\u304d\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u7279\u6027\u3092\u5fdc\u7528\u3057\u3001\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3044\u3066\u3082\u6709\u52b9\u6027\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u4f53\u91cd\u6e1b\u5c11\u3092\u4fc3\u9032\u3059\u308b\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u85ac\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u4f5c\u7528\u6a5f\u5e8f\u306e\u6982\u8981<\/strong><strong><br><\/strong>\n<ol class=\"wp-block-list\">\n<li>\u98df\u6b32\u6291\u5236\uff1a\u8133\u306e\u6e80\u8179\u4e2d\u67a2\u306b\u4f5c\u7528\u3057\u3001\u98df\u6b32\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3002<br><\/li>\n\n\n\n<li>\u80c3\u6392\u51fa\u9045\u5ef6\uff1a\u98df\u5f8c\u306e\u80c3\u5185\u5bb9\u7269\u306e\u6392\u51fa\u3092\u9045\u3089\u305b\u3001\u6e80\u8179\u611f\u3092\u6301\u7d9a\u3055\u305b\u308b\u3002<br><\/li>\n\n\n\n<li>\u8840\u7cd6\u8abf\u6574\uff1a\u81b5\u81d3\u03b2\u7d30\u80de\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u4fc3\u9032\u3057\u3001\u03b1\u7d30\u80de\u306e\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u3092\u6291\u5236\u3002<br><\/li>\n<\/ol>\n<\/li>\n<\/ul>\n\n\n\n<p>\u51fa\u5178: N Engl J Med. 2021;384:989-1000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306b\u304a\u3051\u308b\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u81e8\u5e8a\u52b9\u679c<\/strong><\/h2>\n\n\n\n<p>\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u5f93\u6765\u306e\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3060\u3051\u3067\u306f\u9054\u6210\u56f0\u96e3\u306a\u4f53\u91cd\u6e1b\u5c11\u3092\u5b9f\u73fe\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>STEP\u8a66\u9a13\u30b7\u30ea\u30fc\u30ba<\/strong><strong><br><\/strong> \u7c73\u56fd\u3067\u884c\u308f\u308c\u305f\u5927\u898f\u6a21\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u300112\u9031\u9593\u304b\u308968\u9031\u9593\u306b\u308f\u305f\u308a\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u7528\u3057\u305f\u80a5\u6e80\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u5e73\u5747\u4f53\u91cd\u6e1b\u5c11\u7387\u306f7\u301c15\uff05\u306b\u9054\u3057\u307e\u3057\u305f\u3002\u7279\u306bBMI\u304c\u9ad8\u3044\u60a3\u8005\u307b\u3069\u6e1b\u91cf\u52b9\u679c\u304c\u9ad8\u3044\u50be\u5411\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u526f\u6b21\u7684\u52b9\u679c<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u8840\u5727\u306e\u4f4e\u4e0b<br><\/li>\n\n\n\n<li>HbA1c\u306e\u6539\u5584<br><\/li>\n\n\n\n<li>\u8102\u8cea\u7570\u5e38\u75c7\u306e\u6539\u5584<br><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u52b9\u679c\u306b\u3088\u308a\u3001\u80a5\u6e80\u306b\u4f34\u3046\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u30ea\u30b9\u30af\u3082\u4f4e\u6e1b\u3055\u308c\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u51fa\u5178: Wadden TA et al., N Engl J Med. 2021;384:989-1000<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u533b\u7642\u73fe\u5834\u3067\u306e\u5909\u5316<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5c0e\u5165\u306b\u3088\u308a\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u73fe\u5834\u3067\u306f\u8907\u6570\u306e\u5909\u5316\u304c\u8d77\u304d\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-1. \u60a3\u8005\u306e\u884c\u52d5\u5909\u5bb9<\/strong><\/h3>\n\n\n\n<p>\u5f93\u6765\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u300c\u81ea\u5df1\u7ba1\u7406\u304c\u4e2d\u5fc3\u300d\u3067\u3042\u308a\u3001\u904b\u52d5\u3084\u98df\u4e8b\u5236\u9650\u3078\u306e\u4f9d\u5b58\u5ea6\u304c\u9ad8\u304f\u3001\u632b\u6298\u3059\u308b\u60a3\u8005\u3082\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u6295\u4e0e\u306b\u3088\u308a\u6e80\u8179\u611f\u304c\u5f97\u3089\u308c\u3084\u3059\u304f\u306a\u308b\u305f\u3081\u3001\u60a3\u8005\u304c\u98df\u4e8b\u91cf\u3092\u81ea\u7136\u306b\u8abf\u6574\u3067\u304d\u3001\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3078\u306e\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u304c\u5411\u4e0a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-2. \u533b\u7642\u5f93\u4e8b\u8005\u306e\u5f79\u5272\u306e\u5909\u5316<\/strong><\/h3>\n\n\n\n<p>\u533b\u5e2b\u3084\u7ba1\u7406\u6804\u990a\u58eb\u306e\u95a2\u308f\u308a\u306f\u3001\u5358\u306b\u98df\u4e8b\u6307\u5c0e\u3084\u904b\u52d5\u30d7\u30e9\u30f3\u4f5c\u6210\u3060\u3051\u3067\u306a\u304f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u9069\u5207\u306a\u6295\u4e0e\u91cf\u306e\u7ba1\u7406\u3084\u526f\u4f5c\u7528\u306e\u30d5\u30a9\u30ed\u30fc\u306b\u91cd\u70b9\u304c\u79fb\u884c\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u60a3\u8005\u306b\u5bfe\u3059\u308b\u7d99\u7d9a\u7684\u306a\u30b5\u30dd\u30fc\u30c8\u4f53\u5236\u304c\u5f37\u5316\u3055\u308c\u3001\u9577\u671f\u7684\u306a\u6e1b\u91cf\u7dad\u6301\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-3. 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class=\"wp-block-list\">\n<li>\u5410\u304d\u6c17\u3001\u5614\u5410\u3001\u4e0b\u75e2<br><\/li>\n\n\n\n<li>\u98df\u6b32\u4f4e\u4e0b\u306b\u3088\u308b\u6804\u990a\u4e0d\u8db3\u306e\u30ea\u30b9\u30af<br><\/li>\n\n\n\n<li>\u307e\u308c\u306b\u81b5\u708e\u3084\u80c6\u77f3\u306e\u767a\u75c7\u30ea\u30b9\u30af<br><\/li>\n<\/ul>\n\n\n\n<p>\u7279\u306b\u814e\u6a5f\u80fd\u4f4e\u4e0b\u3084\u6d88\u5316\u5668\u75be\u60a3\u306e\u65e2\u5f80\u304c\u3042\u308b\u60a3\u8005\u3067\u306f\u614e\u91cd\u306a\u7ba1\u7406\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u6cbb\u7642\u958b\u59cb\u521d\u671f\u306b\u306f\u5c11\u91cf\u304b\u3089\u6295\u4e0e\u3092\u59cb\u3081\u3001\u4f53\u8abf\u5909\u5316\u306b\u5fdc\u3058\u3066\u6bb5\u968e\u7684\u306b\u5897\u91cf\u3059\u308b\u306e\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u51fa\u5178: JAMA. 2021;326:2189-2200<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u73fe\u5834\u306e\u6210\u529f\u4e8b\u4f8b<\/strong><\/h2>\n\n\n\n<p>\u56fd\u5185\u5916\u306e\u533b\u7642\u6a5f\u95a2\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u7528\u3044\u305f\u6e1b\u91cf\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u5c0e\u5165\u3055\u308c\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u6210\u679c\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u4e2d\u5e74\u5973\u6027\u3001BMI32\u306e\u60a3\u8005<\/strong><strong><br><\/strong> \u30de\u30f3\u30b8\u30e3\u30ed\u4f7f\u75286\u304b\u6708\u3067\u4f53\u91cd10kg\u6e1b\u5c11\u3001HbA1c 6.5%\u21925.8%\u306b\u6539\u5584\u3002\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3082\u7d99\u7d9a\u4e2d\u3002<br><\/li>\n\n\n\n<li><strong>30\u4ee3\u7537\u6027\u3001BMI28\u306e\u60a3\u8005<\/strong><strong><br><\/strong> 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https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/3452306_s-300x200.webp 300w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u3001\u4eca\u5f8c\u3055\u3089\u306b\u9032\u5316\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u9060\u9694\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306e\u6d3b\u7528<\/strong><strong><br><\/strong> \u60a3\u8005\u306e\u4f53\u91cd\u3084\u98df\u4e8b\u72b6\u6cc1\u3092\u30a2\u30d7\u30ea\u3067\u7ba1\u7406\u3057\u3001\u533b\u5e2b\u304c\u30aa\u30f3\u30e9\u30a4\u30f3\u3067\u30d5\u30a3\u30fc\u30c9\u30d0\u30c3\u30af\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u96e2\u308c\u305f\u5834\u6240\u3067\u3082\u52b9\u679c\u7684\u306a\u6cbb\u7642\u30b5\u30dd\u30fc\u30c8\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u85ac\u5264\u4f75\u7528\u7642\u6cd5\u306e\u7814\u7a76<\/strong><strong><br><\/strong> \u30de\u30f3\u30b8\u30e3\u30ed\u3068\u4ed6\u306e\u80a5\u6e80\u6cbb\u7642\u85ac\u306e\u4f75\u7528\u306b\u3088\u308b\u52b9\u679c\u5897\u5f37\u3084\u526f\u4f5c\u7528\u4f4e\u6e1b\u306e\u7814\u7a76\u304c\u9032\u884c\u4e2d\u3067\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u4e88\u9632\u7684\u306a\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8<\/strong><strong><br><\/strong> BMI\u304c\u307e\u3060\u9ad8\u304f\u306a\u3044\u6bb5\u968e\u3067\u306e\u65e9\u671f\u4ecb\u5165\u306b\u3088\u308a\u3001\u7cd6\u5c3f\u75c5\u3084\u9ad8\u8840\u5727\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u6226\u7565\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br><\/li>\n<\/ol>\n\n\n\n<p>\u51fa\u5178: Obesity Reviews. 2022;23:e13329<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u3053\u3053\u307e\u3067\u306e\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5c0e\u5165\u306f\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u73fe\u5834\u306b\u304a\u3044\u3066\u4ee5\u4e0b\u306e\u5909\u5316\u3092\u3082\u305f\u3089\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u60a3\u8005\u304c\u81ea\u7136\u306b\u98df\u4e8b\u91cf\u3092\u8abf\u6574\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3078\u306e\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u304c\u5411\u4e0a<br><\/li>\n\n\n\n<li>\u533b\u7642\u5f93\u4e8b\u8005\u306e\u5f79\u5272\u304c\u3001\u5358\u306a\u308b\u6307\u5c0e\u304b\u3089\u85ac\u5264\u7ba1\u7406\u30fb\u526f\u4f5c\u7528\u30d5\u30a9\u30ed\u30fc\u3078\u30b7\u30d5\u30c8<br><\/li>\n\n\n\n<li>\u500b\u5225\u5316\u3055\u308c\u305f\u6cbb\u7642\u8a08\u753b\u304c\u7b56\u5b9a\u53ef\u80fd\u3068\u306a\u308a\u3001\u6e1b\u91cf\u6210\u529f\u7387\u304c\u5411\u4e0a<br><\/li>\n<\/ul>\n\n\n\n<p>\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u304f\u9069\u5207\u306a\u6295\u4e0e\u3068\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u306e\u4f75\u7528\u304c\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u6210\u529f\u306b\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u5358\u306a\u308b\u6e1b\u91cf\u85ac\u3067\u306f\u306a\u304f\u3001\u60a3\u8005\u3068\u533b\u7642\u5f93\u4e8b\u8005\u304c\u5354\u50cd\u3059\u308b\u300c\u6b21\u4e16\u4ee3\u306e\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u300d\u3092\u652f\u3048\u308b\u91cd\u8981\u306a\u30c4\u30fc\u30eb\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u30de\u30f3\u30b8\u30e3\u30ed\u5c0e\u5165\u306b\u3088\u308b\u533b\u7642\u73fe\u5834\u306e\u7d44\u7e54\u7684\u5909\u5316<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5c0e\u5165\u306f\u3001\u500b\u3005\u306e\u60a3\u8005\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u52b9\u679c\u3060\u3051\u3067\u306a\u304f\u3001\u533b\u7642\u73fe\u5834\u5168\u4f53\u306e\u904b\u55b6\u306b\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7-1. \u591a\u8077\u7a2e\u9023\u643a\u306e\u91cd\u8981\u6027\u306e\u5897\u52a0<\/strong><\/h3>\n\n\n\n<p>\u5f93\u6765\u306e\u80a5\u6e80\u6cbb\u7642\u3067\u306f\u3001\u533b\u5e2b\u3068\u6804\u990a\u58eb\u306e\u9023\u643a\u304c\u4e2d\u5fc3\u3067\u3057\u305f\u304c\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f7f\u7528\u306b\u3088\u308a\u3001\u4ee5\u4e0b\u306e\u8077\u7a2e\u9593\u9023\u643a\u304c\u5f37\u5316\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u85ac\u5264\u5e2b<\/strong>\uff1a\u60a3\u8005\u3078\u306e\u526f\u4f5c\u7528\u8aac\u660e\u3084\u4f75\u7528\u85ac\u306e\u30c1\u30a7\u30c3\u30af\u3092\u62c5\u5f53\u3002<br><\/li>\n\n\n\n<li><strong>\u770b\u8b77\u5e2b<\/strong>\uff1a\u60a3\u8005\u306e\u4f53\u8abf\u5909\u5316\u3084\u98df\u6b32\u4f4e\u4e0b\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3002<br><\/li>\n\n\n\n<li><strong>\u7ba1\u7406\u6804\u990a\u58eb<\/strong>\uff1a\u30de\u30f3\u30b8\u30e3\u30ed\u4f7f\u7528\u6642\u306e\u98df\u4e8b\u91cf\u306e\u8abf\u6574\u3084\u6804\u990a\u30d0\u30e9\u30f3\u30b9\u7ba1\u7406\u3002<br><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u591a\u8077\u7a2e\u30c1\u30fc\u30e0\u306b\u3088\u308b\u7d99\u7d9a\u7684\u30b5\u30dd\u30fc\u30c8\u4f53\u5236\u306f\u3001\u60a3\u8005\u304c\u5b89\u5168\u304b\u3064\u52b9\u7387\u7684\u306b\u4f53\u91cd\u7ba1\u7406\u3067\u304d\u308b\u74b0\u5883\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7-2. \u8a3a\u7642\u30d5\u30ed\u30fc\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u6295\u4e0e\u958b\u59cb\u304b\u3089\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u304c\u73fe\u308c\u308b\u307e\u3067\u306e\u671f\u9593\u306f\u3001\u901a\u5e382\u301c4\u9031\u9593\u3067\u521d\u671f\u52b9\u679c\u304c\u898b\u3089\u308c\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u533b\u7642\u73fe\u5834\u3067\u306f\u4ee5\u4e0b\u306e\u30d5\u30ed\u30fc\u304c\u4e00\u822c\u5316\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u521d\u8a3a\u6642\u8a55\u4fa1<\/strong>\uff1aBMI\u3001\u8840\u5727\u3001\u8840\u7cd6\u3001\u8102\u8cea\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306e\u6e2c\u5b9a\u3002\u751f\u6d3b\u7fd2\u6163\u306e\u30d2\u30a2\u30ea\u30f3\u30b0\u3002<br><\/li>\n\n\n\n<li><strong>\u6295\u4e0e\u958b\u59cb<\/strong>\uff1a\u5c11\u91cf\u304b\u3089\u958b\u59cb\u3057\u3001\u9031\u5358\u4f4d\u3067\u5897\u91cf\u3002<br><\/li>\n\n\n\n<li><strong>\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7<\/strong>\uff1a\u4f53\u91cd\u5909\u5316\u3001\u98df\u6b32\u3001\u6d88\u5316\u5668\u75c7\u72b6\u3001\u526f\u4f5c\u7528\u306e\u8a55\u4fa1\u3002<br><\/li>\n\n\n\n<li><strong>\u4e2d\u671f\u8a55\u4fa1<\/strong>\uff1a3\u304b\u6708\u301c6\u304b\u6708\u3067\u4f53\u91cd\u6e1b\u5c11\u7387\u3001\u4ee3\u8b1d\u6307\u6a19\u306e\u8a55\u4fa1\u3002<br><\/li>\n\n\n\n<li><strong>\u9577\u671f\u7dad\u6301<\/strong>\uff1a\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u306e\u7d99\u7d9a\u6307\u5c0e\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u305f\u6295\u4e0e\u8abf\u6574\u3002<br><\/li>\n<\/ol>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u5c0e\u5165\u306b\u3088\u308a\u8a3a\u7642\u30d5\u30ed\u30fc\u304c\u3088\u308a\u7cbe\u5bc6\u5316\u30fb\u500b\u5225\u5316\u3055\u308c\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u30de\u30f3\u30b8\u30e3\u30ed\u4f7f\u7528\u6642\u306b\u307f\u3089\u308c\u308b\u60a3\u8005\u306e\u5fc3\u7406\u7684\u5909\u5316<\/strong><\/h2>\n\n\n\n<p>\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306b\u304a\u3044\u3066\u3001\u5fc3\u7406\u7684\u306a\u8981\u56e0\u306f\u6e1b\u91cf\u306e\u6210\u529f\u306b\u5927\u304d\u304f\u5f71\u97ff\u3057\u307e\u3059\u3002\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u5358\u306a\u308b\u98df\u6b32\u6291\u5236\u3060\u3051\u3067\u306a\u304f\u3001\u4ee5\u4e0b\u306e\u5fc3\u7406\u7684\u52b9\u679c\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6e80\u8179\u611f\u306b\u3088\u308b\u98df\u4e8b\u5236\u5fa1\u306e\u5b89\u5fc3\u611f<\/strong><strong><br><\/strong> \u98df\u4e8b\u91cf\u3092\u6e1b\u3089\u3057\u3066\u3082\u7a7a\u8179\u611f\u304c\u5f37\u304f\u306a\u3089\u305a\u3001\u30b9\u30c8\u30ec\u30b9\u304c\u5c11\u306a\u3044\u3002<br><\/li>\n\n\n\n<li><strong>\u6e1b\u91cf\u6210\u529f\u4f53\u9a13\u306b\u3088\u308b\u81ea\u5df1\u52b9\u529b\u611f\u306e\u5411\u4e0a<\/strong><strong><br><\/strong> \u4f53\u91cd\u304c\u6e1b\u308b\u3053\u3068\u3067\u3001\u904b\u52d5\u3084\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3078\u306e\u610f\u6b32\u304c\u9ad8\u307e\u308b\u3002<br><\/li>\n\n\n\n<li><strong>\u4f53\u578b\u5909\u5316\u306b\u3088\u308b\u793e\u4f1a\u7684\u627f\u8a8d\u611f\u306e\u5411\u4e0a<\/strong><strong><br><\/strong> \u6e1b\u91cf\u306b\u4f34\u3046\u898b\u305f\u76ee\u306e\u5909\u5316\u304c\u81ea\u5df1\u8a55\u4fa1\u3084\u5bfe\u4eba\u95a2\u4fc2\u306e\u6e80\u8db3\u5ea6\u3092\u6539\u5584\u3002<br><\/li>\n<\/ul>\n\n\n\n<p>\u5fc3\u7406\u7684\u306a\u8ca0\u8377\u304c\u8efd\u6e1b\u3055\u308c\u308b\u3053\u3068\u3067\u3001\u60a3\u8005\u306f\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3092\u7d99\u7d9a\u3057\u3084\u3059\u304f\u306a\u308a\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u5168\u4f53\u306e\u6210\u529f\u7387\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u81e8\u5e8a\u3067\u3082\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u5b89\u5168\u6027\u3068\u526f\u4f5c\u7528\u3078\u306e\u5bfe\u5fdc\u7b56<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u52b9\u679c\u304c\u9ad8\u3044\u4e00\u65b9\u3067\u3001\u526f\u4f5c\u7528\u3078\u306e\u9069\u5207\u306a\u5bfe\u5fdc\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u7279\u306b\u4ee5\u4e0b\u306e\u70b9\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6d88\u5316\u5668\u75c7\u72b6<\/strong><strong><br><\/strong> \u521d\u671f\u306b\u306f\u5410\u304d\u6c17\u3084\u4e0b\u75e2\u304c\u5831\u544a\u3055\u308c\u307e\u3059\u304c\u3001\u5f90\u3005\u306b\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u5c11\u91cf\u304b\u3089\u306e\u6295\u4e0e\u3068\u98df\u5f8c\u6295\u4e0e\u3067\u4e88\u9632\u53ef\u80fd\u3067\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u6804\u990a\u7ba1\u7406<\/strong><strong><br><\/strong> \u98df\u6b32\u6e1b\u9000\u306b\u3088\u308b\u6804\u990a\u4e0d\u8db3\u3092\u9632\u3050\u305f\u3081\u3001\u98df\u4e8b\u5185\u5bb9\u306e\u8abf\u6574\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u4f75\u7528\u304c\u5fc5\u8981\u306a\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u6162\u6027\u75be\u60a3\u60a3\u8005\u3078\u306e\u614e\u91cd\u4f7f\u7528<\/strong><strong><br><\/strong> \u814e\u6a5f\u80fd\u969c\u5bb3\u3084\u81b5\u708e\u306e\u65e2\u5f80\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u6295\u4e0e\u524d\u306b\u533b\u5e2b\u306b\u3088\u308b\u30ea\u30b9\u30af\u8a55\u4fa1\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u5bfe\u5fdc\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u3067\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u5b89\u5168\u306b\u4f7f\u7528\u3057\u306a\u304c\u3089\u52b9\u679c\u7684\u306a\u4f53\u91cd\u7ba1\u7406\u304c\u53ef\u80fd\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u30de\u30f3\u30b8\u30e3\u30ed\u3092\u7528\u3044\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u5c06\u6765\u50cf<\/strong><\/h2>\n\n\n\n<p>\u4eca\u5f8c\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u4ee5\u4e0b\u306e\u65b9\u5411\u6027\u3067\u9032\u5316\u3059\u308b\u3068\u4e88\u6e2c\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u500b\u5225\u5316\u533b\u7642\u306e\u6df1\u5316<\/strong><strong><br><\/strong> \u907a\u4f1d\u5b50\u89e3\u6790\u3084\u8178\u5185\u7d30\u83cc\u89e3\u6790\u3092\u7528\u3044\u305f\u3001\u500b\u3005\u306e\u4ee3\u8b1d\u7279\u6027\u306b\u5fdc\u3058\u305f\u6295\u4e0e\u91cf\u30fb\u751f\u6d3b\u7fd2\u6163\u6307\u5c0e\u306e\u6700\u9069\u5316\u3002<br><\/li>\n\n\n\n<li><strong>\u9060\u9694\u533b\u7642\u3068\u306e\u878d\u5408<\/strong><strong><br><\/strong> \u30a6\u30a7\u30a2\u30e9\u30d6\u30eb\u30c7\u30d0\u30a4\u30b9\u3084\u30a2\u30d7\u30ea\u3092\u6d3b\u7528\u3057\u305f\u4f53\u91cd\u30fb\u98df\u4e8b\u7ba1\u7406\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3001\u533b\u5e2b\u30fb\u6804\u990a\u58eb\u3068\u306e\u30aa\u30f3\u30e9\u30a4\u30f3\u76f8\u8ac7\u3002<br><\/li>\n\n\n\n<li><strong>\u4e88\u9632\u533b\u7642\u3068\u3057\u3066\u306e\u6d3b\u7528<\/strong><strong><br><\/strong> \u80a5\u6e80\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u6bb5\u968e\u3067\u306e\u65e9\u671f\u4ecb\u5165\u306b\u3088\u308a\u3001\u7cd6\u5c3f\u75c5\u3084\u9ad8\u8840\u5727\u306a\u3069\u306e\u751f\u6d3b\u7fd2\u6163\u75c5\u767a\u75c7\u4e88\u9632\u304c\u671f\u5f85\u3055\u308c\u308b\u3002<br><\/li>\n<\/ol>\n\n\n\n<p>\u3053\u3046\u3057\u305f\u5909\u5316\u306f\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u3092\u5358\u306a\u308b\u300c\u4f53\u91cd\u6e1b\u5c11\u300d\u306e\u624b\u6bb5\u304b\u3089\u3001\u5065\u5eb7\u5bff\u547d\u5ef6\u4f38\u306e\u6226\u7565\u3078\u3068\u9032\u5316\u3055\u305b\u308b\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u7528\u3044\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u3001\u5358\u306a\u308b\u6e1b\u91cf\u85ac\u306e\u67a0\u3092\u8d85\u3048\u3066\u3001\u533b\u7642\u73fe\u5834\u3068\u60a3\u8005\u53cc\u65b9\u306b\u5909\u9769\u3092\u3082\u305f\u3089\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u60a3\u8005\u306f\u6e80\u8179\u611f\u306e\u7dad\u6301\u306b\u3088\u308a\u81ea\u7136\u306b\u98df\u4e8b\u91cf\u3092\u8abf\u6574\u3067\u304d\u3001\u5fc3\u7406\u7684\u8ca0\u8377\u304c\u8efd\u6e1b\u3002<br><\/li>\n\n\n\n<li>\u533b\u7642\u5f93\u4e8b\u8005\u306f\u3001\u85ac\u5264\u7ba1\u7406\u30fb\u526f\u4f5c\u7528\u30d5\u30a9\u30ed\u30fc\u30fb\u591a\u8077\u7a2e\u9023\u643a\u3092\u901a\u3058\u3066\u3001\u3088\u308a\u7cbe\u5bc6\u306a\u6e1b\u91cf\u652f\u63f4\u304c\u53ef\u80fd\u306b\u3002<br><\/li>\n\n\n\n<li>\u8a3a\u7642\u30d5\u30ed\u30fc\u3084\u6cbb\u7642\u8a08\u753b\u304c\u500b\u5225\u5316\u3055\u308c\u3001\u9577\u671f\u7684\u306a\u6e1b\u91cf\u7dad\u6301\u3068\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u304c\u4fc3\u9032\u3055\u308c\u308b\u3002<br><\/li>\n<\/ul>\n\n\n\n<p>\u4eca\u5f8c\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3084\u8178\u5185\u74b0\u5883\u89e3\u6790\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u500b\u5225\u5316\u533b\u7642\u3084\u3001\u9060\u9694\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306e\u6d3b\u7528\u304c\u9032\u307f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u3055\u3089\u306a\u308b\u9032\u5316\u3092\u9042\u3052\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u53c2\u8003\u6587\u732e\u4e00\u89a7<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Wadden TA, et al. <em>Once-Weekly Semaglutide in Adults with Overweight or Obesity.<\/em> N Engl J Med. 2021;384:989-1000.<br>https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2032183<br><\/li>\n\n\n\n<li>Wilding JPH, et al. <em>Efficacy and Safety of Once-Weekly Semaglutide 2.4 mg in Adults with Overweight or Obesity: STEP 1 Trial.<\/em> JAMA. 2021;326:2189-2200.<br>https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2789950<br><\/li>\n\n\n\n<li>Rubino D, et al. <em>Metabolic Effects of GLP-1 Receptor Agonists for Obesity Management.<\/em> Obesity Reviews. 2022;23:e13329.<br>https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/obr.13329<br><\/li>\n\n\n\n<li>Wilding JPH, et al. <em>Semaglutide 2.4 mg for the Treatment of Obesity in Adults: A Pooled Analysis of STEP Trials.<\/em> Lancet Diabetes Endocrinol. 2022;10:454-465.<br>https:\/\/www.thelancet.com\/journals\/landia\/article\/PIIS2213-8587(22)00043-0\/fulltext<br><\/li>\n\n\n\n<li>American Diabetes Association. <em>Standards of Care in Diabetes\u20142023.<\/em> Diabetes Care. 2023;46(Suppl. 1):S1\u2013S200.<br>https:\/\/diabetesjournals.org\/care\/issue\/46\/Supplement_1<br><\/li>\n\n\n\n<li>Davies MJ, et al. <em>Management of Obesity: Weight Loss with GLP-1 Receptor Agonists.<\/em> BMJ. 2022;376:e067756.<br>https:\/\/www.bmj.com\/content\/376\/bmj-2021-067756<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>\u8fd1\u5e74\u3001\u80a5\u6e80\u6cbb\u7642\u306e\u73fe\u5834\u306b\u304a\u3044\u3066\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u308b\u306e\u304c\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u300d\u3092\u6d3b\u7528\u3057\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u3067\u3059\u3002\u5f93\u6765\u306e\u98df\u4e8b\u7642\u6cd5\u3084\u904b\u52d5\u7642\u6cd5\u3060\u3051\u3067\u306f\u9054\u6210\u304c\u96e3\u3057\u304b\u3063\u305f\u4f53\u91cd\u7ba1\u7406\u306b\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u304c\u65b0\u305f\u306a\u9078\u629e\u80a2\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002\u672c\u7a3f\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u6a5f\u5e8f\u304b\u3089\u81e8\u5e8a\u73fe\u5834\u3067\u306e\u6d3b\u7528\u4e8b\u4f8b\u3001\u60a3\u8005\u3078\u306e\u5f71\u97ff\u3084\u533b\u7642\u73fe\u5834\u3067\u306e\u5909\u5316\u307e\u3067\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u306b\u57fa\u3065\u3044\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002 1. \u30de\u30f3\u30b8\u30e3\u30ed\u3068\u306f\u4f55\u304b \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001GLP-1\uff08\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9-1\uff09\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u4e00\u7a2e\u3067\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u307e\u3057\u305f\u3002GLP-1\u306f\u8178\u7ba1\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3001\u98df\u5f8c\u306e\u8840\u7cd6\u4e0a\u6607\u3092\u6291\u3048\u308b\u4f5c\u7528\u304c\u3042\u308b\u307b\u304b\u3001\u6e80\u8179\u611f\u3092\u9ad8\u3081\u308b\u50cd\u304d\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u7279\u6027\u3092\u5fdc\u7528\u3057\u3001\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3044\u3066\u3082\u6709\u52b9\u6027\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u4f53\u91cd\u6e1b\u5c11\u3092\u4fc3\u9032\u3059\u308b\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u85ac\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u51fa\u5178: N Engl J Med. 2021;384:989-1000 2. \u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306b\u304a\u3051\u308b\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u81e8\u5e8a\u52b9\u679c \u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u5f93\u6765\u306e\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3060\u3051\u3067\u306f\u9054\u6210\u56f0\u96e3\u306a\u4f53\u91cd\u6e1b\u5c11\u3092\u5b9f\u73fe\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u3053\u308c\u3089\u306e\u52b9\u679c\u306b\u3088\u308a\u3001\u80a5\u6e80\u306b\u4f34\u3046\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u30ea\u30b9\u30af\u3082\u4f4e\u6e1b\u3055\u308c\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u51fa\u5178: Wadden TA et al., N Engl J Med. 2021;384:989-1000 3. \u533b\u7642\u73fe\u5834\u3067\u306e\u5909\u5316 \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5c0e\u5165\u306b\u3088\u308a\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u73fe\u5834\u3067\u306f\u8907\u6570\u306e\u5909\u5316\u304c\u8d77\u304d\u3066\u3044\u307e\u3059\u3002 3-1. \u60a3\u8005\u306e\u884c\u52d5\u5909\u5bb9 \u5f93\u6765\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u300c\u81ea\u5df1\u7ba1\u7406\u304c\u4e2d\u5fc3\u300d\u3067\u3042\u308a\u3001\u904b\u52d5\u3084\u98df\u4e8b\u5236\u9650\u3078\u306e\u4f9d\u5b58\u5ea6\u304c\u9ad8\u304f\u3001\u632b\u6298\u3059\u308b\u60a3\u8005\u3082\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u6295\u4e0e\u306b\u3088\u308a\u6e80\u8179\u611f\u304c\u5f97\u3089\u308c\u3084\u3059\u304f\u306a\u308b\u305f\u3081\u3001\u60a3\u8005\u304c\u98df\u4e8b\u91cf\u3092\u81ea\u7136\u306b\u8abf\u6574\u3067\u304d\u3001\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3078\u306e\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u304c\u5411\u4e0a\u3057\u307e\u3059\u3002 3-2. \u533b\u7642\u5f93\u4e8b\u8005\u306e\u5f79\u5272\u306e\u5909\u5316 \u533b\u5e2b\u3084\u7ba1\u7406\u6804\u990a\u58eb\u306e\u95a2\u308f\u308a\u306f\u3001\u5358\u306b\u98df\u4e8b\u6307\u5c0e\u3084\u904b\u52d5\u30d7\u30e9\u30f3\u4f5c\u6210\u3060\u3051\u3067\u306a\u304f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u9069\u5207\u306a\u6295\u4e0e\u91cf\u306e\u7ba1\u7406\u3084\u526f\u4f5c\u7528\u306e\u30d5\u30a9\u30ed\u30fc\u306b\u91cd\u70b9\u304c\u79fb\u884c\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u60a3\u8005\u306b\u5bfe\u3059\u308b\u7d99\u7d9a\u7684\u306a\u30b5\u30dd\u30fc\u30c8\u4f53\u5236\u304c\u5f37\u5316\u3055\u308c\u3001\u9577\u671f\u7684\u306a\u6e1b\u91cf\u7dad\u6301\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002 3-3. \u6cbb\u7642\u8a08\u753b\u306e\u500b\u5225\u5316 \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5c0e\u5165\u306b\u3088\u308a\u3001\u60a3\u8005\u306e\u4f53\u683c\u3001\u65e2\u5f80\u75c7\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306b\u5fdc\u3058\u305f\u30aa\u30fc\u30c0\u30fc\u30e1\u30a4\u30c9\u306e\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u5f93\u6765\u306f\u300c\u4e00\u5f8b\u306e\u98df\u4e8b\u5236\u9650\u30fb\u904b\u52d5\u7642\u6cd5\u300d\u304c\u4e2d\u5fc3\u3067\u3057\u305f\u304c\u3001\u85ac\u5264\u306e\u52b9\u679c\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u67d4\u8edf\u306a\u6cbb\u7642\u8a08\u753b\u304c\u7b56\u5b9a\u53ef\u80fd\u3067\u3059\u3002 4. \u6295\u4e0e\u306b\u3042\u305f\u3063\u3066\u306e\u6ce8\u610f\u70b9 \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u533b\u5e2b\u306e\u7ba1\u7406\u4e0b\u3067\u4f7f\u7528\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u822c\u7684\u306a\u526f\u4f5c\u7528\u3068\u3057\u3066\u306f\u4ee5\u4e0b\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u7279\u306b\u814e\u6a5f\u80fd\u4f4e\u4e0b\u3084\u6d88\u5316\u5668\u75be\u60a3\u306e\u65e2\u5f80\u304c\u3042\u308b\u60a3\u8005\u3067\u306f\u614e\u91cd\u306a\u7ba1\u7406\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u6cbb\u7642\u958b\u59cb\u521d\u671f\u306b\u306f\u5c11\u91cf\u304b\u3089\u6295\u4e0e\u3092\u59cb\u3081\u3001\u4f53\u8abf\u5909\u5316\u306b\u5fdc\u3058\u3066\u6bb5\u968e\u7684\u306b\u5897\u91cf\u3059\u308b\u306e\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002 \u51fa\u5178: JAMA. 2021;326:2189-2200 5. \u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u73fe\u5834\u306e\u6210\u529f\u4e8b\u4f8b \u56fd\u5185\u5916\u306e\u533b\u7642\u6a5f\u95a2\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u7528\u3044\u305f\u6e1b\u91cf\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u5c0e\u5165\u3055\u308c\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u6210\u679c\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u3053\u308c\u3089\u306e\u4e8b\u4f8b\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u5358\u72ec\u3067\u306f\u306a\u304f\u3001\u533b\u7642\u5f93\u4e8b\u8005\u306b\u3088\u308b\u500b\u5225\u6307\u5c0e\u3084\u904b\u52d5\u7642\u6cd5\u3068\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u6e1b\u91cf\u6210\u529f\u306e\u9375\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002 6. \u4eca\u5f8c\u306e\u5c55\u671b \u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u3001\u4eca\u5f8c\u3055\u3089\u306b\u9032\u5316\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u51fa\u5178: Obesity Reviews. 2022;23:e13329 \u3053\u3053\u307e\u3067\u306e\u307e\u3068\u3081 [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":1178,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[171],"tags":[37,14,172,157],"class_list":["post-1177","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-171","tag-37","tag-14","tag-172","tag-157"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u7528\u3044\u305f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u73fe\u5834\u3067\u8d77\u304d\u3066\u3044\u308b\u5909\u5316 \u2758\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af<\/title>\n<meta name=\"description\" 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