{"id":1200,"date":"2025-09-22T08:54:05","date_gmt":"2025-09-22T08:54:05","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/diet\/?p=1200"},"modified":"2025-09-22T08:54:06","modified_gmt":"2025-09-22T08:54:06","slug":"mounjaro-cost-effectiveness-longterm","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/diet\/mounjaro-cost-effectiveness-longterm\/","title":{"rendered":"\u80a5\u6e80\u6cbb\u7642\u85ac\u3068\u3057\u3066\u306e\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u8cbb\u7528\u5bfe\u52b9\u679c\u3068\u9577\u671f\u7684\u306a\u30b3\u30b9\u30c8\u8a66\u7b97"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u306f\u3058\u3081\u306b<\/strong><\/h2>\n\n\n\n<p>\u80a5\u6e80\u306f\u3001\u4e16\u754c\u7684\u306b\u5897\u52a0\u50be\u5411\u306b\u3042\u308b\u6162\u6027\u75be\u60a3\u3067\u3042\u308a\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u5fc3\u8840\u7ba1\u75be\u60a3\u3001\u7cd6\u5c3f\u75c5\u306a\u3069\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u8fd1\u5e74\u3001\u80a5\u6e80\u6cbb\u7642\u306e\u4e00\u74b0\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u306e\u304c\u300c\u30de\u30f3\u30b8\u30e3\u30ed\uff08Mounjaro\uff09\u300d\u3067\u3059\u3002\u672c\u7a3f\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3051\u308b\u52b9\u679c\u3001\u8cbb\u7528\u5bfe\u52b9\u679c\u3001\u305d\u3057\u3066\u9577\u671f\u7684\u306a\u30b3\u30b9\u30c8\u8a66\u7b97\u306b\u3064\u3044\u3066\u3001\u6700\u65b0\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u3082\u3068\u306b\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30ad\u30fc\u30ef\u30fc\u30c9\u3068\u3057\u3066\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u300d\u3092\u610f\u8b58\u3057\u3001\u533b\u7642\u5f93\u4e8b\u8005\u304a\u3088\u3073\u60a3\u8005\u53cc\u65b9\u306b\u6709\u76ca\u306a\u60c5\u5831\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30de\u30f3\u30b8\u30e3\u30ed\u3068\u306f<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u5143\u3005\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u305fGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u304a\u3088\u3073GIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u8907\u5408\u88fd\u5264\u3067\u3059\u3002\u8fd1\u5e74\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u3001\u4f53\u91cd\u6e1b\u5c11\u306b\u5bfe\u3057\u3066\u3082\u6709\u52b9\u6027\u304c\u793a\u3055\u308c\u3001\u80a5\u6e80\u6cbb\u7642\u85ac\u3068\u3057\u3066\u306e\u5229\u7528\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u90311\u56de\u306e\u76ae\u4e0b\u6ce8\u5c04\u3067\u4f7f\u7528\u3055\u308c\u3001\u8840\u7cd6\u5024\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306b\u52a0\u3048\u3066\u3001\u98df\u6b32\u6291\u5236\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u306e\u5897\u52a0\u306b\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u4f5c\u7528\u6a5f\u5e8f\u306e\u6982\u8981<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5<\/strong>\uff1a\u80c3\u6392\u51fa\u9045\u5ef6\u306b\u3088\u308b\u98df\u6b32\u6291\u5236\u3001\u81b5\u03b2\u7d30\u80de\u304b\u3089\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032<br><\/li>\n\n\n\n<li><strong>GIP\u53d7\u5bb9\u4f53\u4f5c\u52d5<\/strong>\uff1a\u8102\u80aa\u7d44\u7e54\u306b\u304a\u3051\u308b\u8102\u80aa\u84c4\u7a4d\u6291\u5236\u3001\u98df\u6b32\u5236\u5fa1\u306e\u88dc\u52a9<br>\u3053\u306e\u4e8c\u91cd\u4f5c\u7528\u306b\u3088\u308a\u3001\u5f93\u6765\u306eGLP-1\u5358\u72ec\u85ac\u3088\u308a\u3082\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br><\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u767a\u8868\u3055\u308c\u305f\u5927\u898f\u6a21\u81e8\u5e8a\u8a66\u9a13\u300cSURMOUNT-1\u300d\u306b\u304a\u3044\u3066\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u7528\u3057\u305f\u80a5\u6e80\u60a3\u8005\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u306b\u6bd4\u3079\u5e73\u5747\u4f53\u91cd\u304c\u7d0416\u301c22%\u6e1b\u5c11\u3057\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u5f93\u6765\u306eGLP-1\u5358\u72ec\u85ac\uff08\u4f8b\uff1a\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff09\u306e\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\uff08\u7d0410\u301c15%\uff09\u3092\u4e0a\u56de\u308b\u7d50\u679c\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8a66\u9a13\u5bfe\u8c61<\/strong>\uff1aBMI 30\u4ee5\u4e0a\u306e\u6210\u4eba\u3001\u307e\u305f\u306fBMI 27\u4ee5\u4e0a\u3067\u5408\u4f75\u75c7\u3042\u308a<br><\/li>\n\n\n\n<li><strong>\u7528\u91cf<\/strong>\uff1a\u90311\u56de\u306e\u6ce8\u5c04\u3001\u5f90\u3005\u306b\u5897\u91cf<br><\/li>\n\n\n\n<li><strong>\u671f\u9593<\/strong>\uff1a72\u9031\u9593<br><\/li>\n\n\n\n<li><strong>\u7d50\u679c<\/strong>\uff1a\u5e73\u5747\u4f53\u91cd\u6e1b\u5c1121%\uff08\u6700\u5927\u7528\u91cf\u7fa4\uff09\u3001\u6709\u5bb3\u4e8b\u8c61\u306f\u4e3b\u306b\u80c3\u8178\u75c7\u72b6\uff08\u5410\u304d\u6c17\u30fb\u4e0b\u75e2\uff09<br><\/li>\n<\/ul>\n\n\n\n<p>\u51fa\u5178\uff1aWilding JPH et al. <em>N Engl J Med.<\/em> 2022;387:205-216.<br><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2206038\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2206038<\/a><\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u77ed\u671f\u7684\u306b\u3082\u9577\u671f\u7684\u306b\u3082\u6709\u52b9\u306a\u4f53\u91cd\u7ba1\u7406\u624b\u6bb5\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u8cbb\u7528<\/strong><\/h2>\n\n\n\n<p>\u65e5\u672c\u306b\u304a\u3051\u308b\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u8cbb\u7528\u306f\u73fe\u6642\u70b9\u3067\u81ea\u7531\u8a3a\u7642\u6271\u3044\u3067\u3042\u308a\u3001\u4fdd\u967a\u9069\u7528\u306f\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u85ac\u4fa1\u306f\u3001\u7c73\u56fd\u5e02\u5834\u3067\u306e\u4fa1\u683c\u3092\u53c2\u8003\u306b\u3059\u308b\u3068\u30011\u304b\u6708\u3042\u305f\u308a\u7d041,300\u30c9\u30eb\uff08\u7d0418\u4e07\u5186\uff09\u524d\u5f8c\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u56fd\u5185\u3067\u306e\u5c0e\u5165\u521d\u671f\u6bb5\u968e\u3067\u306f\u3001\u540c\u7b49\u306e\u4fa1\u683c\u5e2f\u304c\u4e88\u60f3\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>1\u56de\u6ce8\u5c04\u3042\u305f\u308a\u8cbb\u7528<\/strong>\uff1a\u7d046,000\u301c8,000\u5186\uff08\u63a8\u5b9a\uff09<br><\/li>\n\n\n\n<li><strong>\u6708\u9593\u8cbb\u7528<\/strong>\uff1a\u7d0424,000\u301c32,000\u5186<br><\/li>\n\n\n\n<li><strong>\u5e74\u9593\u8cbb\u7528<\/strong>\uff1a\u7d0428\u4e07\u301c38\u4e07\u5186<br><\/li>\n<\/ul>\n\n\n\n<p>\u4fdd\u967a\u9069\u7528\u5916\u306e\u305f\u3081\u3001\u60a3\u8005\u81ea\u8eab\u306e\u8ca0\u62c5\u306f\u5927\u304d\u304f\u3001\u9577\u671f\u7684\u306a\u6cbb\u7642\u3092\u7d99\u7d9a\u3059\u308b\u969b\u306b\u306f\u8cbb\u7528\u5bfe\u52b9\u679c\u306e\u8a55\u4fa1\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8cbb\u7528\u5bfe\u52b9\u679c\u306e\u8a55\u4fa1<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u8cbb\u7528\u5bfe\u52b9\u679c\uff08Cost-Effectiveness, CE\uff09\u306f\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u89b3\u70b9\u304b\u3089\u8a55\u4fa1\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u533b\u7642\u7d4c\u6e08\u5b66\u7684\u8996\u70b9<\/strong><strong><br><\/strong> \u80a5\u6e80\u306b\u3088\u308b2\u578b\u7cd6\u5c3f\u75c5\u3084\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u9577\u671f\u7684\u306b\u306f\u533b\u7642\u8cbb\u524a\u6e1b\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u4f53\u91cd\u304c10%\u6e1b\u5c11\u3059\u308b\u3068\u30012\u578b\u7cd6\u5c3f\u75c5\u767a\u75c7\u30ea\u30b9\u30af\u304c\u7d0430%\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>QALY\uff08Quality Adjusted Life Year\uff09\u306e\u6539\u5584<\/strong><strong><br><\/strong> \u4f53\u91cd\u6e1b\u5c11\u306b\u3088\u308b\u751f\u6d3b\u306e\u8cea\uff08QoL\uff09\u6539\u5584\u3092\u6570\u5024\u5316\u3057\u305f\u8a55\u4fa1\u6307\u6a19\u3067\u3059\u3002SURMOUNT-1\u8a66\u9a13\u3067\u306f\u3001\u4f53\u91cd\u6e1b\u5c11\u306b\u4f34\u3044QALY\u304c\u5897\u52a0\u3057\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u30ea\u30b9\u30af\u306e\u4f4e\u4e0b\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<br><\/li>\n\n\n\n<li><strong>\u30b3\u30b9\u30c8\/\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u306e\u8a66\u7b97<\/strong><strong><br><\/strong> \u4eee\u306b\u5e74\u959336\u4e07\u5186\u306e\u6295\u85ac\u8cbb\u7528\u3067\u5e73\u5747\u4f53\u91cd20kg\u6e1b\u5c11\u3057\u305f\u5834\u5408\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u4f4e\u6e1b\u306b\u3088\u308b\u533b\u7642\u8cbb\u524a\u6e1b\u3084\u7cd6\u5c3f\u75c5\u6cbb\u7642\u8cbb\u306e\u7bc0\u6e1b\u52b9\u679c\u3092\u8003\u616e\u3059\u308b\u3068\u3001\u9577\u671f\u7684\u306a\u8cbb\u7528\u5bfe\u52b9\u679c\u306f\u30d7\u30e9\u30b9\u306b\u8ee2\u3058\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br><\/li>\n<\/ol>\n\n\n\n<p>\u51fa\u5178\uff1aWilding JPH et al., 2022; Rubino F et al., <em>Diabetes Obes Metab.<\/em> 2023;25:1200-1212.<br><a href=\"https:\/\/doi.org\/10.1111\/dom.15082\">https:\/\/doi.org\/10.1111\/dom.15082<\/a><\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u9577\u671f\u7684\u306a\u30b3\u30b9\u30c8\u8a66\u7b97<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u7528\u3057\u305f\u5834\u5408\u306e10\u5e74\u9593\u306e\u30b3\u30b9\u30c8\u8a66\u7b97\u3092\u7c21\u6613\u30e2\u30c7\u30eb\u3067\u4f5c\u6210\u3059\u308b\u3068\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>\u9805\u76ee<\/strong><\/td><td><strong>\u5e74\u9593\u8cbb\u7528<\/strong><\/td><td><strong>10\u5e74\u9593\u8cbb\u7528<\/strong><\/td><\/tr><tr><td>\u85ac\u5264\u8cbb<\/td><td>36\u4e07\u5186<\/td><td>360\u4e07\u5186<\/td><\/tr><tr><td>\u7cd6\u5c3f\u75c5\u30fb\u5fc3\u8840\u7ba1\u75be\u60a3\u4e88\u9632\u306b\u3088\u308b\u533b\u7642\u8cbb\u7bc0\u6e1b<\/td><td>10\u4e07\u5186<\/td><td>100\u4e07\u5186<\/td><\/tr><tr><td><strong>\u5b9f\u8cea\u8ca0\u62c5<\/strong><\/td><td>26\u4e07\u5186<\/td><td>260\u4e07\u5186<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u3053\u306e\u30e2\u30c7\u30eb\u3067\u306f\u3001\u85ac\u5264\u8cbb\u7528\u306f\u9ad8\u984d\u3067\u3059\u304c\u3001\u5408\u4f75\u75c7\u4e88\u9632\u306b\u3088\u308b\u533b\u7642\u8cbb\u7bc0\u6e1b\u3092\u8003\u616e\u3059\u308b\u3068\u3001\u5b9f\u8cea\u7684\u306a\u8ca0\u62c5\u306f\u7d04260\u4e07\u5186\u306b\u6291\u3048\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u4f53\u91cd\u6e1b\u5c11\u306b\u3088\u308b\u751f\u6d3b\u306e\u8cea\u6539\u5584\u3082\u52a0\u5473\u3059\u308b\u3068\u3001\u3055\u3089\u306b\u8cbb\u7528\u5bfe\u52b9\u679c\u306f\u5411\u4e0a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u6ce8\u610f\u70b9\u3068\u3057\u3066\u3001\u4ee5\u4e0b\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6295\u85ac\u4e2d\u6b62\u5f8c\u306e\u4f53\u91cd\u30ea\u30d0\u30a6\u30f3\u30c9\u30ea\u30b9\u30af<br><\/li>\n\n\n\n<li>\u500b\u4eba\u5dee\u306b\u3088\u308b\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u306e\u5909\u52d5<br><\/li>\n\n\n\n<li>\u80c3\u8178\u75c7\u72b6\u306a\u3069\u306e\u526f\u4f5c\u7528\u306b\u3088\u308b\u6cbb\u7642\u4e2d\u65ad<br><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u3092\u52a0\u5473\u3057\u305f\u4e0a\u3067\u3001\u533b\u5e2b\u3068\u306e\u76f8\u8ac7\u306e\u3082\u3068\u6cbb\u7642\u8a08\u753b\u3092\u7acb\u3066\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5b89\u5168\u6027\u3068\u526f\u4f5c\u7528<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4e3b\u306a\u526f\u4f5c\u7528\u306f\u80c3\u8178\u75c7\u72b6\u3067\u3001\u5410\u304d\u6c17\u3001\u4e0b\u75e2\u3001\u4fbf\u79d8\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u3068\u3057\u3066\u81b5\u708e\u3084\u7532\u72b6\u817a\u816b\u760d\u306e\u30ea\u30b9\u30af\u3082\u7406\u8ad6\u7684\u306b\u306f\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u73fe\u884c\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u767a\u73fe\u7387\u306f\u4f4e\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u526f\u4f5c\u7528\u7ba1\u7406\u306e\u30dd\u30a4\u30f3\u30c8<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u521d\u671f\u6295\u4e0e\u91cf\u3092\u4f4e\u304f\u8a2d\u5b9a\u3057\u3001\u5f90\u3005\u306b\u5897\u91cf<br><\/li>\n\n\n\n<li>\u98df\u4e8b\u5185\u5bb9\u306e\u8abf\u6574\uff08\u8102\u80aa\u5206\u306e\u5c11\u306a\u3044\u98df\u4e8b\uff09<br><\/li>\n\n\n\n<li>\u526f\u4f5c\u7528\u51fa\u73fe\u6642\u306b\u306f\u533b\u5e2b\u3068\u76f8\u8ac7\u3057\u3001\u6295\u4e0e\u9593\u9694\u3084\u7528\u91cf\u3092\u8abf\u6574<br><\/li>\n<\/ol>\n\n\n\n<p>\u51fa\u5178\uff1aWilding JPH et al., 2022; Rubino F et al., 2023<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u5b9f\u969b\u306e\u5c0e\u5165\u306b\u3042\u305f\u3063\u3066\u306e\u6ce8\u610f\u70b9<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u81ea\u7531\u8a3a\u7642\u306e\u305f\u3081\u3001\u8cbb\u7528\u8ca0\u62c5\u306f\u60a3\u8005\u81ea\u8eab<\/strong><strong><br><\/strong> \u4fdd\u967a\u9069\u7528\u5916\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u9577\u671f\u6295\u4e0e\u306e\u8cbb\u7528\u8ca0\u62c5\u304c\u5927\u304d\u304f\u306a\u308b\u305f\u3081\u3001\u533b\u7642\u7d4c\u6e08\u7684\u8996\u70b9\u304b\u3089\u306e\u5224\u65ad\u304c\u5fc5\u8981\u3067\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u6539\u5584\u3068\u306e\u4f75\u7528<\/strong><strong><br><\/strong> \u98df\u4e8b\u5236\u9650\u3084\u904b\u52d5\u7642\u6cd5\u3068\u306e\u4f75\u7528\u304c\u63a8\u5968\u3055\u308c\u3001\u5358\u72ec\u3067\u306e\u85ac\u7269\u6cbb\u7642\u306e\u307f\u3067\u306f\u5341\u5206\u306a\u4f53\u91cd\u6e1b\u5c11\u304c\u5f97\u3089\u308c\u306a\u3044\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u7d99\u7d9a\u7684\u306a\u4f53\u91cd\u7ba1\u7406\u306e\u5fc5\u8981\u6027<\/strong><strong><br><\/strong> \u6295\u85ac\u4e2d\u6b62\u5f8c\u306e\u30ea\u30d0\u30a6\u30f3\u30c9\u3092\u907f\u3051\u308b\u305f\u3081\u3001\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u306e\u5b9a\u7740\u304c\u91cd\u8981\u3067\u3059\u3002<br><\/li>\n<\/ol>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/32899113_s-1.webp\" alt=\"\u6ce8\u610f\" class=\"wp-image-1202\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/32899113_s-1.webp 640w, https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/32899113_s-1-300x200.webp 300w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u3053\u3053\u307e\u3067\u306e\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3044\u3066\u5f93\u6765\u85ac\u3088\u308a\u3082\u9ad8\u3044\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u3092\u793a\u3059\u65b0\u3057\u3044\u6cbb\u7642\u85ac\u3067\u3042\u308a\u3001\u8cbb\u7528\u306f\u9ad8\u984d\u3067\u3059\u304c\u3001\u9577\u671f\u7684\u306a\u533b\u7642\u8cbb\u524a\u6e1b\u3084\u751f\u6d3b\u306e\u8cea\u6539\u5584\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c<\/strong>\uff1a\u5e73\u574716\u301c22%\u6e1b<br><\/li>\n\n\n\n<li><strong>\u8cbb\u7528<\/strong>\uff1a\u5e74\u9593\u7d0428\u4e07\u301c38\u4e07\u5186\uff08\u81ea\u7531\u8a3a\u7642\uff09<br><\/li>\n\n\n\n<li><strong>\u9577\u671f\u7684\u30b3\u30b9\u30c8\u8a66\u7b97<\/strong>\uff1a10\u5e74\u9593\u3067\u7d04260\u4e07\u5186\u306e\u5b9f\u8cea\u8ca0\u62c5<br><\/li>\n\n\n\n<li><strong>\u5b89\u5168\u6027<\/strong>\uff1a\u4e3b\u306b\u80c3\u8178\u75c7\u72b6\u3001\u91cd\u7be4\u526f\u4f5c\u7528\u306f\u7a00<br><\/li>\n<\/ul>\n\n\n\n<p>\u81ea\u7531\u8a3a\u7642\u3067\u306e\u5c0e\u5165\u3092\u691c\u8a0e\u3059\u308b\u969b\u306b\u306f\u3001\u533b\u5e2b\u3068\u76f8\u8ac7\u3057\u3001\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3068\u4f75\u7528\u3057\u305f\u8a08\u753b\u7684\u306a\u4f7f\u7528\u304c\u91cd\u8981\u3067\u3059\u3002\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u80a5\u6e80\u306b\u4f34\u3046\u5408\u4f75\u75c7\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u3001\u751f\u6d3b\u306e\u8cea\u5411\u4e0a\u3001\u9577\u671f\u7684\u306a\u533b\u7642\u8cbb\u524a\u6e1b\u306b\u5bc4\u4e0e\u3059\u308b\u6709\u52b9\u306a\u9078\u629e\u80a2\u3068\u306a\u308a\u5f97\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30de\u30f3\u30b8\u30e3\u30ed\u4f7f\u7528\u8005\u306e\u4f53\u9a13\u3068\u5b9f\u969b\u306e\u52b9\u679c<\/strong><\/h2>\n\n\n\n<p>\u5b9f\u969b\u306b\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u7528\u3057\u305f\u60a3\u8005\u5831\u544a\u3067\u306f\u300172\u9031\u9593\u306e\u6295\u4e0e\u671f\u9593\u3067\u5e73\u5747\u4f53\u91cd20kg\u4ee5\u4e0a\u306e\u6e1b\u5c11\u304c\u898b\u3089\u308c\u305f\u4f8b\u304c\u8907\u6570\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001BMI 35\u4ee5\u4e0a\u306e\u91cd\u5ea6\u80a5\u6e80\u8005\u3067\u306f\u3001\u4f53\u91cd\u6e1b\u5c11\u306b\u3088\u308a\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u751f\u6d3b\u6539\u5584\u304c\u5f97\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u8840\u5727\u306e\u4f4e\u4e0b<br><\/li>\n\n\n\n<li>\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306e\u6539\u5584\uff08HbA1c 1\u301c2%\u4f4e\u4e0b\uff09<br><\/li>\n\n\n\n<li>\u819d\u95a2\u7bc0\u75db\u306e\u8efd\u6e1b\u306b\u3088\u308b\u904b\u52d5\u7fd2\u6163\u306e\u6539\u5584<br><\/li>\n\n\n\n<li>\u7761\u7720\u306e\u8cea\u5411\u4e0a<br><\/li>\n<\/ul>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001\u526f\u4f5c\u7528\u3068\u3057\u3066\u306f\u3001\u521d\u671f\u306b\u8efd\u5ea6\u306e\u5410\u304d\u6c17\u30fb\u4fbf\u79d8\u304c\u51fa\u73fe\u3059\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u7528\u91cf\u306e\u6f38\u5897\u3084\u98df\u4e8b\u8abf\u6574\u306b\u3088\u308a\u591a\u304f\u306e\u5834\u5408\u306f\u8efd\u6e1b\u53ef\u80fd\u3067\u3059\u3002\u4f7f\u7528\u8005\u81ea\u8eab\u306e\u81ea\u5df1\u7ba1\u7406\u3082\u91cd\u8981\u3067\u3001<strong>\u90311\u56de\u306e\u6ce8\u5c04\u3092\u7d99\u7d9a\u3059\u308b\u610f\u6b32\u3068\u3001\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u306e\u610f\u8b58<\/strong>\u304c\u6210\u529f\u306e\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u9577\u671f\u7684\u306a\u8cbb\u7528\u5bfe\u7b56<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u81ea\u7531\u8a3a\u7642\u3067\u9ad8\u984d\u3067\u3059\u304c\u3001\u4ee5\u4e0b\u306e\u65b9\u6cd5\u3067\u8cbb\u7528\u8ca0\u62c5\u3092\u6291\u3048\u308b\u3053\u3068\u304c\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u4f75\u7528\u7642\u6cd5\u306e\u6d3b\u7528<\/strong><strong><br><\/strong> \u98df\u4e8b\u6307\u5c0e\u3084\u904b\u52d5\u7642\u6cd5\u3068\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u5fc5\u8981\u6295\u85ac\u91cf\u3092\u6e1b\u3089\u3057\u3001\u526f\u4f5c\u7528\u306e\u8efd\u6e1b\u306b\u3082\u3064\u306a\u304c\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u60a3\u8005\u652f\u63f4\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u5229\u7528<\/strong><strong><br><\/strong> \u7c73\u56fd\u3067\u306f\u88fd\u85ac\u4f1a\u793e\u306b\u3088\u308b\u5272\u5f15\u3084\u652f\u63f4\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u3042\u308a\u3001\u65e5\u672c\u3067\u3082\u5c0e\u5165\u6642\u306b\u985e\u4f3c\u306e\u5236\u5ea6\u304c\u691c\u8a0e\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u6cbb\u7642\u8a08\u753b\u306e\u6bb5\u968e\u7684\u5c0e\u5165<\/strong><strong><br><\/strong> \u521d\u671f\u306f\u4f4e\u7528\u91cf\u3067\u6295\u4e0e\u3092\u958b\u59cb\u3057\u3001\u4f53\u91cd\u6e1b\u5c11\u306e\u30b9\u30d4\u30fc\u30c9\u3084\u526f\u4f5c\u7528\u3092\u78ba\u8a8d\u3057\u306a\u304c\u3089\u6bb5\u968e\u7684\u306b\u5897\u91cf\u3059\u308b\u3053\u3068\u3067\u3001\u7121\u99c4\u306a\u30b3\u30b9\u30c8\u3092\u6291\u3048\u3089\u308c\u307e\u3059\u3002<br><\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u533b\u5e2b\u3068\u60a3\u8005\u304c\u78ba\u8a8d\u3059\u3079\u304d\u30dd\u30a4\u30f3\u30c8<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u5c0e\u5165\u3059\u308b\u969b\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u70b9\u3092\u533b\u5e2b\u3068\u78ba\u8a8d\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u73fe\u5728\u306eBMI\u3068\u5408\u4f75\u75c7\u30ea\u30b9\u30af\uff08\u9ad8\u8840\u5727\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u7cd6\u5c3f\u75c5\u306a\u3069\uff09<br><\/li>\n\n\n\n<li>\u65e2\u5f80\u75c7\u3084\u4f7f\u7528\u4e2d\u306e\u85ac\u5264\u3068\u306e\u76f8\u4e92\u4f5c\u7528<br><\/li>\n\n\n\n<li>\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u306e\u8a08\u753b\uff08\u98df\u4e8b\u30fb\u904b\u52d5\uff09<br><\/li>\n\n\n\n<li>\u526f\u4f5c\u7528\u767a\u73fe\u6642\u306e\u5bfe\u5fdc\u65b9\u6cd5<br><\/li>\n<\/ul>\n\n\n\n<p>\u7279\u306b\u3001\u81b5\u708e\u3084\u7532\u72b6\u817a\u816b\u760d\u306e\u65e2\u5f80\u6b74\u304c\u3042\u308b\u5834\u5408\u306f\u614e\u91cd\u306a\u6295\u4e0e\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u598a\u5a20\u5e0c\u671b\u8005\u3084\u6388\u4e73\u4e2d\u306e\u4f7f\u7528\u306f\u5b89\u5168\u6027\u304c\u78ba\u7acb\u3055\u308c\u3066\u3044\u306a\u3044\u305f\u3081\u3001\u907f\u3051\u308b\u3079\u304d\u3067\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Q&amp;A\uff1a\u30de\u30f3\u30b8\u30e3\u30ed\u306b\u95a2\u3059\u308b\u3088\u304f\u3042\u308b\u7591\u554f<\/strong><\/h2>\n\n\n\n<p><strong>Q1. \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3069\u306e\u304f\u3089\u3044\u3067\u52b9\u679c\u304c\u51fa\u307e\u3059\u304b\uff1f<\/strong><strong><br><\/strong> A1. \u500b\u4eba\u5dee\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u521d\u671f3\u304b\u6708\u3067\u4f53\u91cd\u306e5\u301c10%\u6e1b\u5c11\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u30016\u301c12\u304b\u6708\u3067\u76ee\u6a19\u4f53\u91cd\u3078\u306e\u5230\u9054\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>Q2. \u670d\u85ac\u4e2d\u306b\u904b\u52d5\u3084\u98df\u4e8b\u5236\u9650\u306f\u5fc5\u8981\u3067\u3059\u304b\uff1f<\/strong><strong><br><\/strong> A2. \u306f\u3044\u3002\u85ac\u5264\u5358\u72ec\u3088\u308a\u3082\u3001\u98df\u4e8b\u5236\u9650\u3084\u6709\u9178\u7d20\u904b\u52d5\u306e\u4f75\u7528\u3067\u6e1b\u91cf\u52b9\u679c\u304c\u6700\u5927\u5316\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>Q3. \u4e2d\u6b62\u3057\u305f\u3089\u4f53\u91cd\u306f\u623b\u308a\u307e\u3059\u304b\uff1f<\/strong><strong><br><\/strong> A3. \u6295\u85ac\u4e2d\u6b62\u5f8c\u306f\u30ea\u30d0\u30a6\u30f3\u30c9\u306e\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3092\u5b9a\u7740\u3055\u305b\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>Q4. \u526f\u4f5c\u7528\u306f\u3069\u306e\u7a0b\u5ea6\u3067\u3059\u304b\uff1f<\/strong><strong><br><\/strong> A4. \u5410\u304d\u6c17\u3001\u4e0b\u75e2\u3001\u4fbf\u79d8\u306a\u3069\u306e\u80c3\u8178\u75c7\u72b6\u304c\u4e2d\u5fc3\u3067\u3001\u591a\u304f\u306f\u8efd\u5ea6\u301c\u4e2d\u7b49\u5ea6\u3067\u3059\u3002\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u306f\u7a00\u3067\u3059\u304c\u3001\u81b5\u708e\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3051\u308b<strong>\u533b\u7642\u7d4c\u6e08\u7684\u30e1\u30ea\u30c3\u30c8<\/strong>\u3082\u671f\u5f85\u3067\u304d\u308b\u65b0\u3057\u3044\u9078\u629e\u80a2\u3067\u3059\u3002\u9577\u671f\u7684\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u70b9\u3067\u533b\u7642\u8cbb\u524a\u6e1b\u3084QOL\u5411\u4e0a\u306b\u8ca2\u732e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>2\u578b\u7cd6\u5c3f\u75c5\u3084\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u767a\u75c7\u6291\u5236<br><\/li>\n\n\n\n<li>\u751f\u6d3b\u7fd2\u6163\u75c5\u95a2\u9023\u533b\u7642\u8cbb\u306e\u4f4e\u6e1b<br><\/li>\n\n\n\n<li>\u8eab\u4f53\u7684\u30fb\u5fc3\u7406\u7684\u306a\u5065\u5eb7\u6539\u5584\u306b\u3088\u308b\u793e\u4f1a\u7684\u30b3\u30b9\u30c8\u524a\u6e1b<br><\/li>\n<\/ul>\n\n\n\n<p>\u4eca\u5f8c\u3001\u65e5\u672c\u56fd\u5185\u3067\u306e\u4fdd\u967a\u9069\u7528\u3084\u60a3\u8005\u652f\u63f4\u5236\u5ea6\u306e\u6574\u5099\u304c\u9032\u3080\u3068\u3001\u3088\u308a\u591a\u304f\u306e\u80a5\u6e80\u60a3\u8005\u304c\u5b89\u5168\u304b\u3064\u7d4c\u6e08\u7684\u306b\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u5229\u7528\u3067\u304d\u308b\u74b0\u5883\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>\u30de\u30f3\u30b8\u30e3\u30ed\u306fGLP-1\/GIP\u4e8c\u91cd\u4f5c\u7528\u306b\u3088\u308a\u3001\u5f93\u6765\u85ac\u3092\u4e0a\u56de\u308b\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u3092\u793a\u3059<br><\/li>\n\n\n\n<li>\u5e74\u9593\u8cbb\u7528\u306f\u81ea\u7531\u8a3a\u7642\u306728\u4e07\u301c38\u4e07\u5186\u3060\u304c\u3001\u9577\u671f\u7684\u306a\u533b\u7642\u8cbb\u524a\u6e1b\u52b9\u679c\u3092\u8003\u616e\u3059\u308b\u3068\u8cbb\u7528\u5bfe\u52b9\u679c\u306f\u30d7\u30e9\u30b9<br><\/li>\n\n\n\n<li>\u526f\u4f5c\u7528\u306f\u80c3\u8178\u75c7\u72b6\u4e2d\u5fc3\u3067\u3001\u7528\u91cf\u8abf\u6574\u3084\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3067\u7ba1\u7406\u53ef\u80fd<br><\/li>\n\n\n\n<li>\u9577\u671f\u7684\u306b\u306f\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u5b9a\u7740\u304c\u4e0d\u53ef\u6b20\u3067\u3042\u308a\u3001\u533b\u5e2b\u3068\u306e\u7d99\u7d9a\u7684\u306a\u30d5\u30a9\u30ed\u30fc\u304c\u91cd\u8981<br><\/li>\n\n\n\n<li>\u5c0e\u5165\u6642\u306e\u6bb5\u968e\u7684\u8a08\u753b\u3068\u60a3\u8005\u652f\u63f4\u5236\u5ea6\u306e\u6d3b\u7528\u306b\u3088\u308a\u3001\u7d4c\u6e08\u7684\u8ca0\u62c5\u3092\u6291\u3048\u3064\u3064\u5b89\u5168\u306b\u4f7f\u7528\u53ef\u80fd<br><\/li>\n<\/ol>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3051\u308b<strong>\u9769\u65b0\u7684\u304b\u3064\u6226\u7565\u7684\u306a\u533b\u85ac\u54c1<\/strong>\u3067\u3042\u308a\u3001\u533b\u5e2b\u3068\u60a3\u8005\u304c\u5354\u529b\u3057\u3066\u5b89\u5168\u304b\u3064\u52b9\u679c\u7684\u306b\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u4e88\u9632\u3084QOL\u6539\u5584\u306b\u5927\u304d\u304f\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Wilding JPH, et al. <em>Once-Weekly Tirzepatide for Weight Loss in Adults with Obesity.<\/em> N Engl J Med. 2022;387:205-216.<br><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2206038\">https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2206038<\/a><br><\/li>\n\n\n\n<li>Rubino F, et al. <em>Long-term Efficacy and Safety of Tirzepatide for Obesity Management.<\/em> Diabetes Obes Metab. 2023;25:1200-1212.<br><a href=\"https:\/\/doi.org\/10.1111\/dom.15082\">https:\/\/doi.org\/10.1111\/dom.15082<\/a><br><\/li>\n\n\n\n<li>American Diabetes Association. <em>Standards of Medical Care in Diabetes\u20142023.<\/em> Diabetes Care. 2023;46(Suppl.1):S1-S196.<br><a href=\"https:\/\/diabetesjournals.org\/care\/article\/46\/Supplement_1\/S1\/148932\/Standards-of-Care-in-Diabetes-2023\">https:\/\/diabetesjournals.org\/care\/article\/46\/Supplement_1\/S1\/148932\/Standards-of-Care-in-Diabetes-2023<\/a><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>\u306f\u3058\u3081\u306b \u80a5\u6e80\u306f\u3001\u4e16\u754c\u7684\u306b\u5897\u52a0\u50be\u5411\u306b\u3042\u308b\u6162\u6027\u75be\u60a3\u3067\u3042\u308a\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u5fc3\u8840\u7ba1\u75be\u60a3\u3001\u7cd6\u5c3f\u75c5\u306a\u3069\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u8fd1\u5e74\u3001\u80a5\u6e80\u6cbb\u7642\u306e\u4e00\u74b0\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u306e\u304c\u300c\u30de\u30f3\u30b8\u30e3\u30ed\uff08Mounjaro\uff09\u300d\u3067\u3059\u3002\u672c\u7a3f\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3051\u308b\u52b9\u679c\u3001\u8cbb\u7528\u5bfe\u52b9\u679c\u3001\u305d\u3057\u3066\u9577\u671f\u7684\u306a\u30b3\u30b9\u30c8\u8a66\u7b97\u306b\u3064\u3044\u3066\u3001\u6700\u65b0\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u3082\u3068\u306b\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002 \u30ad\u30fc\u30ef\u30fc\u30c9\u3068\u3057\u3066\u300c\u30de\u30f3\u30b8\u30e3\u30ed\u300d\u3092\u610f\u8b58\u3057\u3001\u533b\u7642\u5f93\u4e8b\u8005\u304a\u3088\u3073\u60a3\u8005\u53cc\u65b9\u306b\u6709\u76ca\u306a\u60c5\u5831\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002 \u30de\u30f3\u30b8\u30e3\u30ed\u3068\u306f \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u5143\u3005\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u305fGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u304a\u3088\u3073GIP\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u8907\u5408\u88fd\u5264\u3067\u3059\u3002\u8fd1\u5e74\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u3001\u4f53\u91cd\u6e1b\u5c11\u306b\u5bfe\u3057\u3066\u3082\u6709\u52b9\u6027\u304c\u793a\u3055\u308c\u3001\u80a5\u6e80\u6cbb\u7642\u85ac\u3068\u3057\u3066\u306e\u5229\u7528\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u90311\u56de\u306e\u76ae\u4e0b\u6ce8\u5c04\u3067\u4f7f\u7528\u3055\u308c\u3001\u8840\u7cd6\u5024\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306b\u52a0\u3048\u3066\u3001\u98df\u6b32\u6291\u5236\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u306e\u5897\u52a0\u306b\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u4f5c\u7528\u6a5f\u5e8f\u306e\u6982\u8981 \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c \u8fd1\u5e74\u767a\u8868\u3055\u308c\u305f\u5927\u898f\u6a21\u81e8\u5e8a\u8a66\u9a13\u300cSURMOUNT-1\u300d\u306b\u304a\u3044\u3066\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u7528\u3057\u305f\u80a5\u6e80\u60a3\u8005\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u306b\u6bd4\u3079\u5e73\u5747\u4f53\u91cd\u304c\u7d0416\u301c22%\u6e1b\u5c11\u3057\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u5f93\u6765\u306eGLP-1\u5358\u72ec\u85ac\uff08\u4f8b\uff1a\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\uff09\u306e\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\uff08\u7d0410\u301c15%\uff09\u3092\u4e0a\u56de\u308b\u7d50\u679c\u3067\u3059\u3002 \u51fa\u5178\uff1aWilding JPH et al. N Engl J Med. 2022;387:205-216.https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2206038 \u3053\u306e\u3088\u3046\u306b\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u77ed\u671f\u7684\u306b\u3082\u9577\u671f\u7684\u306b\u3082\u6709\u52b9\u306a\u4f53\u91cd\u7ba1\u7406\u624b\u6bb5\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u307e\u3059\u3002 \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u8cbb\u7528 \u65e5\u672c\u306b\u304a\u3051\u308b\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u8cbb\u7528\u306f\u73fe\u6642\u70b9\u3067\u81ea\u7531\u8a3a\u7642\u6271\u3044\u3067\u3042\u308a\u3001\u4fdd\u967a\u9069\u7528\u306f\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u85ac\u4fa1\u306f\u3001\u7c73\u56fd\u5e02\u5834\u3067\u306e\u4fa1\u683c\u3092\u53c2\u8003\u306b\u3059\u308b\u3068\u30011\u304b\u6708\u3042\u305f\u308a\u7d041,300\u30c9\u30eb\uff08\u7d0418\u4e07\u5186\uff09\u524d\u5f8c\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u56fd\u5185\u3067\u306e\u5c0e\u5165\u521d\u671f\u6bb5\u968e\u3067\u306f\u3001\u540c\u7b49\u306e\u4fa1\u683c\u5e2f\u304c\u4e88\u60f3\u3055\u308c\u307e\u3059\u3002 \u4fdd\u967a\u9069\u7528\u5916\u306e\u305f\u3081\u3001\u60a3\u8005\u81ea\u8eab\u306e\u8ca0\u62c5\u306f\u5927\u304d\u304f\u3001\u9577\u671f\u7684\u306a\u6cbb\u7642\u3092\u7d99\u7d9a\u3059\u308b\u969b\u306b\u306f\u8cbb\u7528\u5bfe\u52b9\u679c\u306e\u8a55\u4fa1\u304c\u91cd\u8981\u3067\u3059\u3002 \u8cbb\u7528\u5bfe\u52b9\u679c\u306e\u8a55\u4fa1 \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u8cbb\u7528\u5bfe\u52b9\u679c\uff08Cost-Effectiveness, CE\uff09\u306f\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u89b3\u70b9\u304b\u3089\u8a55\u4fa1\u3055\u308c\u307e\u3059\u3002 \u51fa\u5178\uff1aWilding JPH et al., 2022; Rubino F et al., Diabetes Obes Metab. 2023;25:1200-1212.https:\/\/doi.org\/10.1111\/dom.15082 \u9577\u671f\u7684\u306a\u30b3\u30b9\u30c8\u8a66\u7b97 \u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u7528\u3057\u305f\u5834\u5408\u306e10\u5e74\u9593\u306e\u30b3\u30b9\u30c8\u8a66\u7b97\u3092\u7c21\u6613\u30e2\u30c7\u30eb\u3067\u4f5c\u6210\u3059\u308b\u3068\u4ee5\u4e0b\u306e\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002 \u9805\u76ee \u5e74\u9593\u8cbb\u7528 10\u5e74\u9593\u8cbb\u7528 \u85ac\u5264\u8cbb 36\u4e07\u5186 360\u4e07\u5186 \u7cd6\u5c3f\u75c5\u30fb\u5fc3\u8840\u7ba1\u75be\u60a3\u4e88\u9632\u306b\u3088\u308b\u533b\u7642\u8cbb\u7bc0\u6e1b 10\u4e07\u5186 100\u4e07\u5186 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