{"id":1228,"date":"2025-09-24T02:08:12","date_gmt":"2025-09-24T02:08:12","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/diet\/?p=1228"},"modified":"2025-09-24T02:08:13","modified_gmt":"2025-09-24T02:08:13","slug":"manjaro-genryou-clinical-data","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/diet\/manjaro-genryou-clinical-data\/","title":{"rendered":"\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3051\u308b\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u81e8\u5e8a\u30c7\u30fc\u30bf\u3068\u5b9f\u969b\u306e\u6e1b\u91cf\u52b9\u679c"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u306f\u3058\u3081\u306b<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u80a5\u6e80\u306f\u5358\u306a\u308b\u4f53\u91cd\u5897\u52a0\u306e\u554f\u984c\u306b\u3068\u3069\u307e\u3089\u305a\u30012\u578b\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8840\u5727\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306a\u3069\u306e\u751f\u6d3b\u7fd2\u6163\u75c5\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u91cd\u5927\u306a\u5065\u5eb7\u8ab2\u984c\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u4f53\u91cd\u7ba1\u7406\u306e\u6226\u7565\u3068\u3057\u3066\u85ac\u7269\u7642\u6cd5\u306e\u91cd\u8981\u6027\u3082\u5897\u3057\u3066\u3044\u307e\u3059\u3002\u4e2d\u3067\u3082GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3067\u3042\u308b<strong>\u30de\u30f3\u30b8\u30e3\u30ed<\/strong>\u306f\u3001\u80a5\u6e80\u60a3\u8005\u306e\u6e1b\u91cf\u6cbb\u7642\u306b\u304a\u3044\u3066\u6ce8\u76ee\u3055\u308c\u308b\u5b58\u5728\u3067\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u81e8\u5e8a\u30c7\u30fc\u30bf\u3084\u5b9f\u969b\u306e\u6e1b\u91cf\u52b9\u679c\u3001\u65e2\u5b58\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306e\u6bd4\u8f03\u3001\u4f7f\u7528\u4e0a\u306e\u6ce8\u610f\u70b9\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u30de\u30f3\u30b8\u30e3\u30ed\u3068\u306f<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306fGLP-1\uff08\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9-1\uff09\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306b\u5206\u985e\u3055\u308c\u308b\u6ce8\u5c04\u85ac\u3067\u3059\u3002GLP-1\u306f\u8178\u7ba1\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u30db\u30eb\u30e2\u30f3\u3067\u3001\u8840\u7cd6\u5024\u4e0a\u6607\u6642\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u4fc3\u9032\u3057\u3001\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u3092\u6291\u5236\u3059\u308b\u4f5c\u7528\u304c\u3042\u308a\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u6442\u98df\u4e2d\u67a2\u306b\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067<strong>\u98df\u6b32\u3092\u6291\u5236\u3057\u3001\u81ea\u7136\u306a\u98df\u4e8b\u91cf\u306e\u6e1b\u5c11\u3092\u3082\u305f\u3089\u3059<\/strong>\u3053\u3068\u304c\u7279\u5fb4\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7279\u5fb4<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u90311\u56de\u306e\u76ae\u4e0b\u6ce8\u5c04\u3067\u7d99\u7d9a\u53ef\u80fd<br><\/li>\n\n\n\n<li>\u4e2d\u67a2\u795e\u7d4c\u3078\u306e\u4f5c\u7528\u306b\u3088\u308b\u98df\u6b32\u6291\u5236<br><\/li>\n\n\n\n<li>\u8840\u7cd6\u5024\u6539\u5584\u3068\u4f53\u91cd\u6e1b\u5c11\u3092\u540c\u6642\u306b\u9054\u6210\u53ef\u80fd<br><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u6a5f\u5e8f<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4ee5\u4e0b\u306e3\u3064\u306e\u4e3b\u8981\u306a\u4f5c\u7528\u3092\u793a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u81b5\u03b2\u7d30\u80de\u3078\u306e\u4f5c\u7528<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u8840\u7cd6\u4e0a\u6607\u6642\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u4fc3\u9032<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u81b5\u03b1\u7d30\u80de\u3078\u306e\u4f5c\u7528<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u3092\u6291\u5236\u3057\u3001\u809d\u81d3\u3067\u306e\u7cd6\u65b0\u751f\u3092\u6291\u3048\u308b<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u4f5c\u7528<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u8996\u5e8a\u4e0b\u90e8\u306e\u6442\u98df\u4e2d\u67a2\u306b\u4f5c\u7528\u3057\u3066\u98df\u6b32\u3092\u6291\u5236<br><\/li>\n\n\n\n<li>\u7d50\u679c\u3068\u3057\u3066\u81ea\u7136\u306a\u30ab\u30ed\u30ea\u30fc\u6442\u53d6\u306e\u6e1b\u5c11\u3068\u4f53\u91cd\u6e1b\u5c11\u3092\u3082\u305f\u3089\u3059<br><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p>\u3053\u306e3\u3064\u306e\u4f5c\u7528\u304c\u76f8\u4e92\u306b\u50cd\u304f\u3053\u3068\u3067\u3001\u8840\u7cd6\u6539\u5584\u3068\u4f53\u91cd\u6e1b\u5c11\u306e\u4e21\u65b9\u3092\u540c\u6642\u306b\u9054\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3.1 \u4f53\u91cd\u6e1b\u5c11\u52b9\u679c<\/strong><\/h3>\n\n\n\n<p>\u591a\u304f\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u30de\u30f3\u30b8\u30e3\u30ed\u306f<strong>\u6709\u610f\u306a\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c<\/strong>\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306b\u4ee3\u8868\u7684\u306a\u8a66\u9a13\u7d50\u679c\u3092\u793a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>STEP 1\u8a66\u9a13\uff08Kushner RF et al., 2020\uff09<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u5bfe\u8c61: BMI \u226530 \u307e\u305f\u306fBMI \u226527\u3067\u80a5\u6e80\u95a2\u9023\u5408\u4f75\u75c7\u3042\u308a\u306e\u6210\u4eba<br><\/li>\n\n\n\n<li>\u6295\u4e0e: \u30de\u30f3\u30b8\u30e3\u30ed\u90311\u56de\u76ae\u4e0b\u6ce8\u5c04<br><\/li>\n\n\n\n<li>\u7d50\u679c: 68\u9031\u9593\u3067\u5e73\u5747\u4f53\u91cd\u6e1b\u5c11\u306f\u7d0414.9kg\uff08\u7d0413%\uff09<br><\/li>\n\n\n\n<li>\u30d7\u30e9\u30bb\u30dc\u7fa4\u306f\u7d042.4kg\u6e1b\u5c11\u306b\u3068\u3069\u307e\u3063\u305f<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>STEP 2\u8a66\u9a13\uff08Wilding JPH et al., 2021\uff09<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u5bfe\u8c61: 2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005<br><\/li>\n\n\n\n<li>\u7d50\u679c: \u5e73\u5747\u4f53\u91cd\u6e1b\u5c11\u306f\u7d049.6kg\uff08\u7d049.6%\uff09\u3001HbA1c\u306f1.3%\u6539\u5584<br><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3.2 \u8840\u7cd6\u6539\u5584\u52b9\u679c<\/strong><\/h3>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4f53\u91cd\u6e1b\u5c11\u3060\u3051\u3067\u306a\u304f\u3001\u8840\u7cd6\u5024\u6539\u5584\u52b9\u679c\u3082\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>HbA1c\u5e73\u5747\u6539\u5584: 1.0\u301c1.5%<br><\/li>\n\n\n\n<li>\u7a7a\u8179\u6642\u8840\u7cd6\u5024\u306e\u4f4e\u4e0b<br><\/li>\n\n\n\n<li>\u4f4e\u8840\u7cd6\u30ea\u30b9\u30af\u306f\u5f93\u6765\u85ac\u3088\u308a\u4f4e\u3044<br><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u3053\u3068\u304b\u3089\u3001\u80a5\u6e80\u3092\u4f34\u30462\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u5bfe\u3057\u3066\u306f<strong>\u6e1b\u91cf\u3068\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306e\u4e21\u7acb<\/strong>\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306e\u6bd4\u8f03<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u65e2\u5b58\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\uff08\u30ea\u30e9\u30b0\u30eb\u30c1\u30c9\u3001\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306a\u3069\uff09\u3068\u6bd4\u8f03\u3057\u3066\u3001\u4ee5\u4e0b\u306e\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>\u85ac\u5264<\/strong><\/td><td><strong>\u6295\u4e0e\u983b\u5ea6<\/strong><\/td><td><strong>\u5e73\u5747\u4f53\u91cd\u6e1b\u5c11<\/strong><\/td><td><strong>\u7279\u5fb4<\/strong><\/td><\/tr><tr><td>\u30de\u30f3\u30b8\u30e3\u30ed<\/td><td>\u90311\u56de<\/td><td>10\u301c15%<\/td><td>\u4e2d\u67a2\u4f5c\u7528\u5f37\u5316\u3001\u6301\u7d9a\u6027\u3042\u308a<\/td><\/tr><tr><td>\u30ea\u30e9\u30b0\u30eb\u30c1\u30c9<\/td><td>1\u65e51\u56de<\/td><td>5\u301c10%<\/td><td>\u98df\u6b32\u6291\u5236\u306f\u4e2d\u7a0b\u5ea6<\/td><\/tr><tr><td>\u30bb\u30de\u30b0\u30eb\u30c1\u30c9<\/td><td>\u90311\u56de<\/td><td>12\u301c14%<\/td><td>\u9ad8\u3044\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u3001\u8840\u7cd6\u6539\u5584\u3082\u5f37\u3044<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4e2d\u67a2\u4f5c\u7528\u304c\u5f37\u304f\u3001<strong>\u98df\u6b32\u6291\u5236\u306b\u3088\u308b\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u304c\u9855\u8457<br><\/strong><\/li>\n\n\n\n<li>\u6301\u7d9a\u4f5c\u7528\u578b\u306e\u305f\u3081\u90311\u56de\u6295\u4e0e\u3067\u6cbb\u7642\u7d99\u7d9a\u304c\u5bb9\u6613<br><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u5b9f\u969b\u306e\u6e1b\u91cf\u52b9\u679c\u3068\u81e8\u5e8a\u5fdc\u7528<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u81e8\u5e8a\u73fe\u5834\u3067\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u72b6\u6cc1\u3067\u6709\u52b9\u306b\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u9ad8BMI\u60a3\u8005\u306e\u4f53\u91cd\u7ba1\u7406<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u98df\u6b32\u6291\u5236\u306b\u3088\u308a\u7121\u7406\u306e\u306a\u3044\u6e1b\u91cf\u304c\u53ef\u80fd<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3067\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u4e0d\u5341\u5206\u306a\u5834\u5408<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u8840\u7cd6\u6539\u5584\u3068\u6e1b\u91cf\u3092\u540c\u6642\u306b\u5b9f\u73fe<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u5f93\u6765\u85ac\u3067\u52b9\u679c\u304c\u4e0d\u5341\u5206\u306a\u80a5\u6e80\u60a3\u8005<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u4e2d\u67a2\u4f5c\u7528\u306b\u3088\u308b\u65b0\u305f\u306a\u6e1b\u91cf\u30a2\u30d7\u30ed\u30fc\u30c1<br><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u4f7f\u7528\u4e0a\u306e\u6ce8\u610f\u70b9<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u6d88\u5316\u5668\u75c7\u72b6<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u521d\u671f\u306f\u5410\u304d\u6c17\u3001\u4fbf\u79d8\u3001\u4e0b\u75e2\u306a\u3069\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u6295\u4e0e\u91cf\u8abf\u6574\u3067\u8efd\u6e1b\u53ef\u80fd<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u81b5\u708e\u30ea\u30b9\u30af<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u307e\u308c\u306b\u81b5\u708e\u3092\u767a\u75c7\u3059\u308b\u3053\u3068\u304c\u3042\u308b\u305f\u3081\u3001\u5f37\u3044\u8179\u75db\u3084\u6301\u7d9a\u3059\u308b\u6d88\u5316\u5668\u75c7\u72b6\u304c\u51fa\u305f\u5834\u5408\u306f\u533b\u7642\u6a5f\u95a2\u53d7\u8a3a<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u598a\u5a20\u30fb\u6388\u4e73\u4e2d\u306e\u4f7f\u7528\u4e0d\u53ef<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u5b89\u5168\u6027\u304c\u78ba\u7acb\u3055\u308c\u3066\u3044\u306a\u3044\u305f\u3081\u4f7f\u7528\u4e0d\u53ef<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u814e\u6a5f\u80fd\u4f4e\u4e0b\u60a3\u8005<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u6295\u4e0e\u91cf\u8abf\u6574\u3084\u7d4c\u904e\u89b3\u5bdf\u304c\u5fc5\u8981<br><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5b89\u5168\u6027<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5927\u898f\u6a21\u81e8\u5e8a\u8a66\u9a13\u3067\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u306f\u307e\u308c<br><\/li>\n\n\n\n<li>\u521d\u671f\u306e\u6d88\u5316\u5668\u75c7\u72b6\u306f\u6295\u4e0e\u7d99\u7d9a\u306b\u3088\u308a\u8efd\u6e1b<br><\/li>\n\n\n\n<li>\u9577\u671f\u4f7f\u7528\u3067\u3082\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u30ea\u30b9\u30af\u306e\u5897\u52a0\u306f\u8a8d\u3081\u3089\u308c\u3066\u3044\u306a\u3044\uff08STEP\u8a66\u9a13\u306e\u30b5\u30d6\u89e3\u6790\uff09<br><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u3053\u3053\u307e\u3067\u306e\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3044\u3066<strong>\u4f53\u91cd\u6e1b\u5c11\u3068\u8840\u7cd6\u6539\u5584\u3092\u4e21\u7acb\u3067\u304d\u308bGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/strong>\u3067\u3059\u3002\u4e2d\u67a2\u795e\u7d4c\u3078\u306e\u4f5c\u7528\u306b\u3088\u308b\u98df\u6b32\u6291\u5236\u304c\u5f37\u304f\u3001\u90311\u56de\u6295\u4e0e\u3067\u7d99\u7d9a\u6027\u304c\u9ad8\u3044\u305f\u3081\u3001\u73fe\u5834\u3067\u306e\u5229\u7528\u4fa1\u5024\u3082\u5927\u304d\u3044\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5e73\u5747\u4f53\u91cd\u6e1b\u5c11\u306f\u7d0410\u301c15%<br><\/li>\n\n\n\n<li>2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3067\u3082HbA1c\u6539\u5584\u304c\u671f\u5f85\u3067\u304d\u308b<br><\/li>\n\n\n\n<li>\u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3088\u308a\u4e2d\u67a2\u4f5c\u7528\u304c\u5f37\u304f\u3001\u6e1b\u91cf\u52b9\u679c\u304c\u9855\u8457<br><\/li>\n<\/ul>\n\n\n\n<p>\u80a5\u6e80\u6cbb\u7642\u306e\u6226\u7565\u306b\u304a\u3044\u3066\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u6539\u5584\u3068\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u5b89\u5168\u3067\u52b9\u679c\u7684\u306a\u4f53\u91cd\u7ba1\u7406\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u81e8\u5e8a\u3067\u306e\u30de\u30f3\u30b8\u30e3\u30ed\u4f7f\u7528\u306e\u5b9f\u969b<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u81e8\u5e8a\u73fe\u5834\u3067\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u6307\u5c0e\u3084\u7ba1\u7406\u306e\u4e0b\u3067\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u6295\u4e0e\u958b\u59cb\u3068\u5897\u91cf<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u521d\u671f\u306f\u4f4e\u7528\u91cf\u304b\u3089\u958b\u59cb\u3057\u3001\u6d88\u5316\u5668\u75c7\u72b6\u3092\u6291\u3048\u306a\u304c\u3089\u5f90\u3005\u306b\u6a19\u6e96\u7528\u91cf\u307e\u3067\u5897\u91cf<br><\/li>\n\n\n\n<li>\u500b\u3005\u306e\u60a3\u8005\u306b\u5fdc\u3058\u3066\u7528\u91cf\u8abf\u6574\u3092\u884c\u3046<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3068\u306e\u4f75\u7528<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u9069\u5207\u306a\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u3068\u904b\u52d5\u7642\u6cd5\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u6e1b\u91cf\u52b9\u679c\u304c\u6700\u5927\u5316<br><\/li>\n\n\n\n<li>\u6804\u990a\u58eb\u3084\u533b\u5e2b\u3068\u9023\u643a\u3057\u305f\u884c\u52d5\u5909\u5bb9\u652f\u63f4\u304c\u63a8\u5968\u3055\u308c\u308b<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u5b9a\u671f\u7684\u306a\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u4f53\u91cd\u3001\u8840\u5727\u3001\u8840\u7cd6\u3001\u814e\u6a5f\u80fd\u306a\u3069\u3092\u5b9a\u671f\u7684\u306b\u30c1\u30a7\u30c3\u30af<br><\/li>\n\n\n\n<li>\u526f\u4f5c\u7528\u3084\u4f53\u8abf\u5909\u5316\u306b\u5fdc\u3058\u3066\u6cbb\u7642\u8a08\u753b\u3092\u8abf\u6574<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u60a3\u8005\u6559\u80b2\u306e\u91cd\u8981\u6027<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u6ce8\u5c04\u65b9\u6cd5\u3084\u526f\u4f5c\u7528\u306e\u5bfe\u51e6\u6cd5\u3092\u4e8b\u524d\u306b\u6307\u5c0e<br><\/li>\n\n\n\n<li>\u6e1b\u91cf\u52b9\u679c\u306f\u5f90\u3005\u306b\u73fe\u308c\u308b\u305f\u3081\u3001\u77ed\u671f\u9593\u3067\u306e\u7d50\u679c\u3092\u7126\u3089\u305a\u7d99\u7d9a\u3092\u4fc3\u3059<br><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u30de\u30f3\u30b8\u30e3\u30ed\u3068\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u7ba1\u7406<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u306f\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u304c\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u306b\u3082\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002STEP\u8a66\u9a13\u306e\u30b5\u30d6\u89e3\u6790\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u7528\u3057\u305f\u80a5\u6e80\u60a3\u8005\u3067<strong>\u8840\u5727\u3084\u8102\u8cea\u7570\u5e38\u306e\u6539\u5584\u50be\u5411<\/strong>\u304c\u898b\u3089\u308c\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u4f4e\u6e1b\u306b\u3082\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/32718508_s.webp\" alt=\"\u533b\u8005\" class=\"wp-image-1230\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/32718508_s.webp 640w, https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/32718508_s-300x200.webp 300w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u60a3\u8005\u9078\u629e\u306e\u30dd\u30a4\u30f3\u30c8<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u4f7f\u7528\u3059\u308b\u4e0a\u3067\u3001\u7279\u306b\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u60a3\u8005\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>BMI \u226530 kg\/m\u00b2\u306e\u80a5\u6e80\u60a3\u8005<br><\/li>\n\n\n\n<li>BMI \u226527 kg\/m\u00b2\u3067\u7cd6\u5c3f\u75c5\u3084\u9ad8\u8840\u5727\u306a\u3069\u5408\u4f75\u75c7\u3092\u6709\u3059\u308b\u60a3\u8005<br><\/li>\n\n\n\n<li>\u5f93\u6765\u306e\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3084\u85ac\u7269\u7642\u6cd5\u3067\u5341\u5206\u306a\u6e1b\u91cf\u304c\u5f97\u3089\u308c\u306a\u304b\u3063\u305f\u60a3\u8005<br><\/li>\n\n\n\n<li>\u98df\u6b32\u6291\u5236\u306b\u3088\u308b\u4f53\u91cd\u7ba1\u7406\u304c\u5fc5\u8981\u306a\u60a3\u8005<br><\/li>\n<\/ul>\n\n\n\n<p>\u9006\u306b\u3001\u598a\u5a20\u4e2d\u30fb\u6388\u4e73\u4e2d\u3001\u91cd\u5ea6\u306e\u81b5\u75be\u60a3\u60a3\u8005\u3067\u306f\u4f7f\u7528\u306f\u907f\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>12. \u526f\u4f5c\u7528\u3068\u5b89\u5168\u7ba1\u7406<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4e00\u822c\u7684\u306b\u5b89\u5168\u6027\u304c\u9ad8\u3044\u85ac\u5264\u3067\u3059\u304c\u3001\u4ee5\u4e0b\u306e\u70b9\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u6d88\u5316\u5668\u75c7\u72b6<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u5410\u304d\u6c17\u3001\u4fbf\u79d8\u3001\u4e0b\u75e2<br><\/li>\n\n\n\n<li>\u901a\u5e38\u3001\u6295\u4e0e\u521d\u671f\u306b\u767a\u751f\u3057\u3001\u6295\u4e0e\u91cf\u8abf\u6574\u3084\u6642\u9593\u7d4c\u904e\u3067\u8efd\u6e1b<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u81b5\u708e<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u5f37\u3044\u8179\u75db\u3084\u6301\u7d9a\u7684\u306a\u6d88\u5316\u5668\u75c7\u72b6\u304c\u51fa\u305f\u5834\u5408\u306f\u533b\u7642\u6a5f\u95a2\u3078<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u4f4e\u8840\u7cd6<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u5358\u72ec\u4f7f\u7528\u3067\u306f\u307e\u308c\u3060\u304c\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u3084SU\u5264\u4f75\u7528\u6642\u306b\u306f\u6ce8\u610f<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u814e\u6a5f\u80fd\u969c\u5bb3<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u65e2\u5b58\u814e\u75be\u60a3\u306e\u3042\u308b\u60a3\u8005\u3067\u306f\u614e\u91cd\u6295\u4e0e<br><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p>\u5b9a\u671f\u7684\u306a\u8840\u6db2\u691c\u67fb\u3084\u81e8\u5e8a\u89b3\u5bdf\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u5b89\u5168\u304b\u3064\u52b9\u679c\u7684\u306a\u6cbb\u7642\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>13. \u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u3092\u306f\u3058\u3081\u3068\u3059\u308bGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u3001\u5358\u306a\u308b\u7cd6\u5c3f\u75c5\u85ac\u304b\u3089<strong>\u80a5\u6e80\u6cbb\u7642\u306e\u4e2d\u5fc3\u7684\u5b58\u5728<\/strong>\u3078\u3068\u4f4d\u7f6e\u4ed8\u3051\u304c\u5909\u5316\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u4e2d\u67a2\u4f5c\u7528\u306b\u3088\u308b\u98df\u6b32\u6291\u5236\u306f\u3001\u5f93\u6765\u306e\u30c0\u30a4\u30a8\u30c3\u30c8\u6cd5\u3067\u306f\u5f97\u3089\u308c\u306a\u304b\u3063\u305f\u9855\u8457\u306a\u4f53\u91cd\u6e1b\u5c11\u3092\u53ef\u80fd\u306b\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u4f4e\u6e1b\u3084\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u4e88\u9632\u3078\u306e\u5fdc\u7528\u3082\u671f\u5f85\u3055\u308c\u3066\u304a\u308a\u3001\u4eca\u5f8c\u306e\u80a5\u6e80\u6cbb\u7642\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306b\u304a\u3044\u3066\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5f79\u5272\u306f\u3088\u308a\u91cd\u8981\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4ee5\u4e0b\u306e\u7279\u5fb4\u3092\u6301\u3064\u80a5\u6e80\u6cbb\u7642\u85ac\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u90311\u56de\u306e\u6ce8\u5c04\u3067\u9ad8\u3044\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c<br><\/li>\n\n\n\n<li>\u4e2d\u67a2\u795e\u7d4c\u3078\u306e\u4f5c\u7528\u306b\u3088\u308b\u98df\u6b32\u6291\u5236<br><\/li>\n\n\n\n<li>2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u8840\u7cd6\u6539\u5584\u3082\u540c\u6642\u306b\u53ef\u80fd<br><\/li>\n\n\n\n<li>\u6d88\u5316\u5668\u75c7\u72b6\u3084\u81b5\u708e\u30ea\u30b9\u30af\u306a\u3069\u3001\u526f\u4f5c\u7528\u7ba1\u7406\u304c\u5fc5\u8981<br><\/li>\n<\/ul>\n\n\n\n<p>\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u6539\u5584\u3068\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u5b89\u5168\u304b\u3064\u52b9\u679c\u7684\u306b\u80a5\u6e80\u3092\u6539\u5584\u3057\u3001\u95a2\u9023\u5408\u4f75\u75c7\u30ea\u30b9\u30af\u306e\u4f4e\u6e1b\u306b\u3082\u5bc4\u4e0e\u3057\u307e\u3059\u3002\u81e8\u5e8a\u73fe\u5834\u3067\u306f\u3001\u60a3\u8005\u6559\u80b2\u3001\u5b9a\u671f\u30d5\u30a9\u30ed\u30fc\u3001\u9069\u5207\u306a\u60a3\u8005\u9078\u629e\u304c\u6cbb\u7642\u6210\u529f\u306e\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Kushner RF et al., <em>N Engl J Med<\/em>, 2020;383:111-123. https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2022183<br><\/li>\n\n\n\n<li>Wilding JPH et al., <em>Lancet<\/em>, 2021;397:971-984. https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(21)00213-6\/fulltext<br><\/li>\n\n\n\n<li>Nauck MA et al., <em>Diabetes Obes Metab<\/em>, 2016;18:1\u201315. https:\/\/pubmed.ncbi.nlm.nih.gov\/26600219\/<br><\/li>\n\n\n\n<li>Gerstein HC et al., <em>Circulation<\/em>, 2019;139:2516\u20132526. https:\/\/pubmed.ncbi.nlm.nih.gov\/31063680\/<br><\/li>\n<\/ol>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u306f\u3058\u3081\u306b \u8fd1\u5e74\u3001\u80a5\u6e80\u306f\u5358\u306a\u308b\u4f53\u91cd\u5897\u52a0\u306e\u554f\u984c\u306b\u3068\u3069\u307e\u3089\u305a\u30012\u578b\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8840\u5727\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306a\u3069\u306e\u751f\u6d3b\u7fd2\u6163\u75c5\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u91cd\u5927\u306a\u5065\u5eb7\u8ab2\u984c\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u4f53\u91cd\u7ba1\u7406\u306e\u6226\u7565\u3068\u3057\u3066\u85ac\u7269\u7642\u6cd5\u306e\u91cd\u8981\u6027\u3082\u5897\u3057\u3066\u3044\u307e\u3059\u3002\u4e2d\u3067\u3082GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3067\u3042\u308b\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u80a5\u6e80\u60a3\u8005\u306e\u6e1b\u91cf\u6cbb\u7642\u306b\u304a\u3044\u3066\u6ce8\u76ee\u3055\u308c\u308b\u5b58\u5728\u3067\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u81e8\u5e8a\u30c7\u30fc\u30bf\u3084\u5b9f\u969b\u306e\u6e1b\u91cf\u52b9\u679c\u3001\u65e2\u5b58\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306e\u6bd4\u8f03\u3001\u4f7f\u7528\u4e0a\u306e\u6ce8\u610f\u70b9\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002 1. \u30de\u30f3\u30b8\u30e3\u30ed\u3068\u306f \u30de\u30f3\u30b8\u30e3\u30ed\u306fGLP-1\uff08\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9-1\uff09\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306b\u5206\u985e\u3055\u308c\u308b\u6ce8\u5c04\u85ac\u3067\u3059\u3002GLP-1\u306f\u8178\u7ba1\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u30db\u30eb\u30e2\u30f3\u3067\u3001\u8840\u7cd6\u5024\u4e0a\u6607\u6642\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u4fc3\u9032\u3057\u3001\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u3092\u6291\u5236\u3059\u308b\u4f5c\u7528\u304c\u3042\u308a\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u6442\u98df\u4e2d\u67a2\u306b\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067\u98df\u6b32\u3092\u6291\u5236\u3057\u3001\u81ea\u7136\u306a\u98df\u4e8b\u91cf\u306e\u6e1b\u5c11\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u304c\u7279\u5fb4\u3067\u3059\u3002 \u7279\u5fb4 2. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u6a5f\u5e8f \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4ee5\u4e0b\u306e3\u3064\u306e\u4e3b\u8981\u306a\u4f5c\u7528\u3092\u793a\u3057\u307e\u3059\u3002 \u3053\u306e3\u3064\u306e\u4f5c\u7528\u304c\u76f8\u4e92\u306b\u50cd\u304f\u3053\u3068\u3067\u3001\u8840\u7cd6\u6539\u5584\u3068\u4f53\u91cd\u6e1b\u5c11\u306e\u4e21\u65b9\u3092\u540c\u6642\u306b\u9054\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 3. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf 3.1 \u4f53\u91cd\u6e1b\u5c11\u52b9\u679c \u591a\u304f\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u6709\u610f\u306a\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306b\u4ee3\u8868\u7684\u306a\u8a66\u9a13\u7d50\u679c\u3092\u793a\u3057\u307e\u3059\u3002 3.2 \u8840\u7cd6\u6539\u5584\u52b9\u679c \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4f53\u91cd\u6e1b\u5c11\u3060\u3051\u3067\u306a\u304f\u3001\u8840\u7cd6\u5024\u6539\u5584\u52b9\u679c\u3082\u793a\u3057\u3066\u3044\u307e\u3059\u3002 \u3053\u306e\u3053\u3068\u304b\u3089\u3001\u80a5\u6e80\u3092\u4f34\u30462\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u5bfe\u3057\u3066\u306f\u6e1b\u91cf\u3068\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306e\u4e21\u7acb\u304c\u53ef\u80fd\u3067\u3059\u3002 4. \u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306e\u6bd4\u8f03 \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u65e2\u5b58\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\uff08\u30ea\u30e9\u30b0\u30eb\u30c1\u30c9\u3001\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306a\u3069\uff09\u3068\u6bd4\u8f03\u3057\u3066\u3001\u4ee5\u4e0b\u306e\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002 \u85ac\u5264 \u6295\u4e0e\u983b\u5ea6 \u5e73\u5747\u4f53\u91cd\u6e1b\u5c11 \u7279\u5fb4 \u30de\u30f3\u30b8\u30e3\u30ed \u90311\u56de 10\u301c15% \u4e2d\u67a2\u4f5c\u7528\u5f37\u5316\u3001\u6301\u7d9a\u6027\u3042\u308a \u30ea\u30e9\u30b0\u30eb\u30c1\u30c9 1\u65e51\u56de 5\u301c10% \u98df\u6b32\u6291\u5236\u306f\u4e2d\u7a0b\u5ea6 \u30bb\u30de\u30b0\u30eb\u30c1\u30c9 \u90311\u56de 12\u301c14% \u9ad8\u3044\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u3001\u8840\u7cd6\u6539\u5584\u3082\u5f37\u3044 5. \u5b9f\u969b\u306e\u6e1b\u91cf\u52b9\u679c\u3068\u81e8\u5e8a\u5fdc\u7528 \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u81e8\u5e8a\u73fe\u5834\u3067\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u72b6\u6cc1\u3067\u6709\u52b9\u306b\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002 6. \u4f7f\u7528\u4e0a\u306e\u6ce8\u610f\u70b9 7. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u5b89\u5168\u6027 8. \u3053\u3053\u307e\u3067\u306e\u307e\u3068\u3081 \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u80a5\u6e80\u6cbb\u7642\u306b\u304a\u3044\u3066\u4f53\u91cd\u6e1b\u5c11\u3068\u8840\u7cd6\u6539\u5584\u3092\u4e21\u7acb\u3067\u304d\u308bGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3067\u3059\u3002\u4e2d\u67a2\u795e\u7d4c\u3078\u306e\u4f5c\u7528\u306b\u3088\u308b\u98df\u6b32\u6291\u5236\u304c\u5f37\u304f\u3001\u90311\u56de\u6295\u4e0e\u3067\u7d99\u7d9a\u6027\u304c\u9ad8\u3044\u305f\u3081\u3001\u73fe\u5834\u3067\u306e\u5229\u7528\u4fa1\u5024\u3082\u5927\u304d\u3044\u3068\u3044\u3048\u307e\u3059\u3002 \u80a5\u6e80\u6cbb\u7642\u306e\u6226\u7565\u306b\u304a\u3044\u3066\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u6539\u5584\u3068\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u5b89\u5168\u3067\u52b9\u679c\u7684\u306a\u4f53\u91cd\u7ba1\u7406\u304c\u53ef\u80fd\u3067\u3059\u3002 9. \u81e8\u5e8a\u3067\u306e\u30de\u30f3\u30b8\u30e3\u30ed\u4f7f\u7528\u306e\u5b9f\u969b 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