{"id":1232,"date":"2025-09-24T02:16:45","date_gmt":"2025-09-24T02:16:45","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/diet\/?p=1232"},"modified":"2025-09-24T02:16:50","modified_gmt":"2025-09-24T02:16:50","slug":"manjaro-glp1-sakyou-sa","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/diet\/manjaro-glp1-sakyou-sa\/","title":{"rendered":"\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u6a5f\u5e8f\u3068\u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306e\u660e\u78ba\u306a\u9055\u3044"},"content":{"rendered":"\n<p>\u8fd1\u5e74\u3001\u80a5\u6e80\u30842\u578b\u7cd6\u5c3f\u75c5\u306b\u5bfe\u3059\u308b\u85ac\u7269\u7642\u6cd5\u3068\u3057\u3066\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\uff08GLP-1 RAs\uff09\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4e2d\u3067\u3082\u3001<strong>\u30de\u30f3\u30b8\u30e3\u30ed<\/strong>\u306f\u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u6bd4\u3079\u3066\u7279\u5fb4\u7684\u306a\u4f5c\u7528\u6a5f\u5e8f\u3068\u81e8\u5e8a\u52b9\u679c\u3092\u793a\u3059\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u6a5f\u5e8f\u3001\u4f53\u91cd\u6e1b\u5c11\u3084\u8840\u7cd6\u6539\u5584\u3078\u306e\u5f71\u97ff\u3001\u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306e\u9055\u3044\u3001\u305d\u3057\u3066\u81e8\u5e8a\u8a66\u9a13\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u6574\u7406\u3057\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306f<\/strong><\/h2>\n\n\n\n<p>GLP-1\uff08Glucagon-Like Peptide-1\uff09\u306f\u3001\u8178\u7ba1\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3001\u98df\u4e8b\u6442\u53d6\u5f8c\u306b\u8840\u7cd6\u3092\u8abf\u7bc0\u3059\u308b\u5f79\u5272\u3092\u6301\u3061\u307e\u3059\u3002GLP-1\u306f\u4ee5\u4e0b\u306e\u4f5c\u7528\u3092\u901a\u3058\u3066\u8840\u7cd6\u5024\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u81b5\u81d3\u03b2\u7d30\u80de\u304b\u3089\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\uff08\u8840\u7cd6\u4f9d\u5b58\u6027\uff09<br><\/li>\n\n\n\n<li>\u81b5\u81d3\u03b1\u7d30\u80de\u304b\u3089\u306e\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u6291\u5236<br><\/li>\n\n\n\n<li>\u80c3\u6392\u51fa\u306e\u9045\u5ef6\u306b\u3088\u308b\u6e80\u8179\u611f\u306e\u5897\u52a0<br><\/li>\n\n\n\n<li>\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u4f5c\u7528\u306b\u3088\u308b\u98df\u6b32\u6291\u5236<br><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u4f5c\u7528\u306b\u6ce8\u76ee\u3057\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u80a5\u6e80\u6cbb\u7642\u30842\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306b\u5fdc\u7528\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u30de\u30f3\u30b8\u30e3\u30ed\u3068\u306f<\/strong><\/h2>\n\n\n\n<p><strong>\u30de\u30f3\u30b8\u30e3\u30ed<\/strong>\u306f\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u4e00\u7a2e\u3067\u3042\u308a\u3001\u90311\u56de\u306e\u76ae\u4e0b\u6ce8\u5c04\u3067\u6295\u4e0e\u53ef\u80fd\u306a\u85ac\u5264\u3067\u3059\u3002\u65e5\u672c\u56fd\u5185\u3067\u306f\u80a5\u6e80\u6cbb\u7642\u30842\u578b\u7cd6\u5c3f\u75c5\u7ba1\u7406\u306b\u7528\u3044\u3089\u308c\u308b\u3053\u3068\u304c\u5897\u3048\u3066\u304a\u308a\u3001\u7279\u306b\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u306e\u9ad8\u3055\u3067\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4e3b\u306a\u7279\u5fb4\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u9ad8\u9078\u629e\u6027\u306eGLP-1\u53d7\u5bb9\u4f53\u7d50\u5408<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u03b2\u7d30\u80de\u306b\u5f37\u304f\u7d50\u5408\u3057\u3001\u8840\u7cd6\u4f9d\u5b58\u6027\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u4fc3\u9032<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u4f5c\u7528\u5f37\u5316<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u98df\u6b32\u6291\u5236\u3084\u6e80\u8179\u611f\u306e\u5897\u52a0\u304c\u5f93\u6765\u85ac\u3088\u308a\u9855\u8457<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u9577\u6642\u9593\u4f5c\u7528\u578b<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>1\u9031\u9593\u306b1\u56de\u306e\u6295\u4e0e\u3067\u5b89\u5b9a\u3057\u305f\u8840\u4e2d\u6fc3\u5ea6\u3092\u7dad\u6301<br><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u6a5f\u5e8f<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u306f\u3001\u5f93\u6765\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u540c\u69d8\u306b\u8840\u7cd6\u4f9d\u5b58\u6027\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\u3068\u30b0\u30eb\u30ab\u30b4\u30f3\u6291\u5236\u3092\u884c\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001<strong>\u72ec\u81ea\u306e\u5206\u5b50\u69cb\u9020\u306b\u3088\u308a\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u79fb\u884c\u6027\u304c\u9ad8\u304f\u3001\u98df\u6b32\u6291\u5236\u4f5c\u7528\u304c\u5f37\u5316\u3055\u308c\u3066\u3044\u308b<\/strong>\u70b9\u304c\u4ed6\u5264\u3068\u306e\u5927\u304d\u306a\u9055\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-1. \u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\u3068\u8840\u7cd6\u6539\u5584<\/strong><\/h3>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u81b5\u03b2\u7d30\u80de\u306eGLP-1\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u3001cAMP\u7d4c\u8def\u3092\u6d3b\u6027\u5316\u3057\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002\u8840\u7cd6\u4f9d\u5b58\u6027\u3067\u3042\u308b\u305f\u3081\u3001\u4f4e\u8840\u7cd6\u30ea\u30b9\u30af\u304c\u5c11\u306a\u3044\u70b9\u3082\u5229\u70b9\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-2. \u30b0\u30eb\u30ab\u30b4\u30f3\u6291\u5236<\/strong><\/h3>\n\n\n\n<p>\u81b5\u03b1\u7d30\u80de\u306b\u4f5c\u7528\u3057\u3066\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u3092\u6291\u5236\u3057\u3001\u809d\u81d3\u3067\u306e\u7cd6\u65b0\u751f\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u8840\u7cd6\u4e0a\u6607\u3092\u6291\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-3. \u80c3\u6392\u51fa\u9045\u5ef6\u306b\u3088\u308b\u6e80\u8179\u611f\u5897\u52a0<\/strong><\/h3>\n\n\n\n<p>\u80c3\u6392\u51fa\u3092\u9045\u3089\u305b\u308b\u3053\u3068\u3067\u3001\u98df\u5f8c\u306e\u8840\u7cd6\u4e0a\u6607\u3092\u6291\u5236\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u6e80\u8179\u611f\u3092\u9577\u6642\u9593\u7dad\u6301\u3057\u307e\u3059\u3002\u3053\u306e\u4f5c\u7528\u306f\u98df\u6b32\u6291\u5236\u306b\u76f4\u7d50\u3057\u3001\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u3092\u9ad8\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-4. \u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u4f5c\u7528<\/strong><\/h3>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u8840\u6db2\u8133\u95a2\u9580\u3092\u901a\u904e\u3057\u3084\u3059\u3044\u8a2d\u8a08\u3068\u306a\u3063\u3066\u304a\u308a\u3001\u8996\u5e8a\u4e0b\u90e8\u306e\u98df\u6b32\u4e2d\u67a2\u306b\u76f4\u63a5\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u6442\u98df\u91cf\u3092\u6291\u5236<\/strong>\u3057\u307e\u3059\u3002\u3053\u306e\u4e2d\u67a2\u4f5c\u7528\u304c\u5f93\u6765\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3088\u308a\u5f37\u5316\u3055\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u3088\u308a\u9855\u8457\u306a\u4f53\u91cd\u6e1b\u5c11\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306e\u9055\u3044<\/strong><\/h2>\n\n\n\n<p>GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306b\u306f\u3001\u30ea\u30e9\u30b0\u30eb\u30c1\u30c9\u3001\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u3001\u30c7\u30e5\u30e9\u30b0\u30eb\u30c1\u30c9\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\u30de\u30f3\u30b8\u30e3\u30ed\u3068\u6bd4\u8f03\u3057\u305f\u969b\u306e\u4e3b\u306a\u9055\u3044\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>\u85ac\u5264<\/strong><\/td><td><strong>\u6295\u4e0e\u983b\u5ea6<\/strong><\/td><td><strong>\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c<\/strong><\/td><td><strong>\u4e2d\u67a2\u4f5c\u7528<\/strong><\/td><td><strong>\u8840\u7cd6\u6539\u5584<\/strong><\/td><\/tr><tr><td>\u30de\u30f3\u30b8\u30e3\u30ed<\/td><td>\u90311\u56de<\/td><td>\u9ad8<\/td><td>\u5f37<\/td><td>\u9ad8<\/td><\/tr><tr><td>\u30ea\u30e9\u30b0\u30eb\u30c1\u30c9<\/td><td>\u6bce\u65e5<\/td><td>\u4e2d<\/td><td>\u4e2d<\/td><td>\u9ad8<\/td><\/tr><tr><td>\u30bb\u30de\u30b0\u30eb\u30c1\u30c9<\/td><td>\u90311\u56de<\/td><td>\u9ad8<\/td><td>\u5f37<\/td><td>\u9ad8<\/td><\/tr><tr><td>\u30c7\u30e5\u30e9\u30b0\u30eb\u30c1\u30c9<\/td><td>\u90311\u56de<\/td><td>\u4e2d<\/td><td>\u4e2d<\/td><td>\u9ad8<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u7279\u5fb4<\/strong>\u306f\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u4f5c\u7528\u5f37\u5316\u306b\u3088\u308b<strong>\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u306e\u9ad8\u3055<\/strong>\u306b\u3042\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u4ed6\u5264\u3082\u8840\u7cd6\u6539\u5584\u52b9\u679c\u306f\u9ad8\u3044\u3082\u306e\u306e\u3001\u98df\u6b32\u6291\u5236\u3084\u4f53\u91cd\u6e1b\u5c11\u306e\u7a0b\u5ea6\u306b\u5dee\u304c\u3042\u308a\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u81e8\u5e8a\u8a66\u9a13\u306b\u304a\u3051\u308b\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u52b9\u679c<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u80a5\u6e80\u60a3\u8005\u304a\u3088\u30732\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u591a\u6570\u306e\u81e8\u5e8a\u8a66\u9a13\u304c\u5b9f\u65bd\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5-1. \u4f53\u91cd\u6e1b\u5c11\u52b9\u679c<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u90311\u56de\u6295\u4e0e\u306712\u9031\u9593\u301c68\u9031\u9593\u306e\u8a66\u9a13\u671f\u9593\u4e2d\u3001**\u5e73\u5747\u4f53\u91cd\u6e1b\u5c11\u306f7\u301c15\uff05**\u5831\u544a<br><\/li>\n\n\n\n<li>BMI 30\u4ee5\u4e0a\u306e\u80a5\u6e80\u60a3\u8005\u3067\u3082\u6709\u610f\u306a\u6e1b\u91cf\u52b9\u679c\u3092\u793a\u3059<br><\/li>\n\n\n\n<li>\u98df\u4e8b\u5236\u9650\u3084\u904b\u52d5\u7642\u6cd5\u3068\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u3055\u3089\u306b\u52b9\u679c\u304c\u5897\u5f37<br><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5-2. \u8840\u7cd6\u6539\u5584\u52b9\u679c<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>HbA1c\u4f4e\u4e0b\u306f1.0\u301c1.5\uff05\u7a0b\u5ea6\u5831\u544a<br><\/li>\n\n\n\n<li>\u8840\u7cd6\u4f9d\u5b58\u6027\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\u306e\u305f\u3081\u3001\u4f4e\u8840\u7cd6\u30ea\u30b9\u30af\u306f\u4f4e\u3044<br><\/li>\n\n\n\n<li>\u7279\u306b\u9ad8\u8840\u7cd6\u60a3\u8005\u3067\u6539\u5584\u52b9\u679c\u304c\u9855\u8457<br><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5-3. \u5b89\u5168\u6027<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u4e3b\u306a\u526f\u4f5c\u7528\u306f<strong>\u5410\u304d\u6c17\u30fb\u4fbf\u79d8\u30fb\u4e0b\u75e2<\/strong>\u306a\u3069\u306e\u6d88\u5316\u5668\u75c7\u72b6<br><\/li>\n\n\n\n<li>\u91cd\u7be4\u306a\u4f4e\u8840\u7cd6\u3084\u81b5\u708e\u306f\u307e\u308c<br><\/li>\n\n\n\n<li>\u9577\u671f\u6295\u4e0e\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\u3078\u306e\u5f71\u97ff\u306f\u4eca\u5f8c\u3082\u7814\u7a76\u304c\u7d99\u7d9a\u4e2d<br><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u30de\u30f3\u30b8\u30e3\u30ed\u3092\u6d3b\u7528\u3057\u305f\u30c0\u30a4\u30a8\u30c3\u30c8\u6226\u7565<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u5358\u72ec\u3067\u306e\u4f7f\u7528\u3067\u3082\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u4ee5\u4e0b\u306e\u30dd\u30a4\u30f3\u30c8\u3092\u62bc\u3055\u3048\u308b\u3053\u3068\u3067\u3088\u308a\u5b89\u5168\u304b\u3064\u52b9\u679c\u7684\u306b\u6d3b\u7528\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3068\u4f75\u7528<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u6804\u990a\u30d0\u30e9\u30f3\u30b9\u306e\u53d6\u308c\u305f\u98df\u4e8b\u3068\u904b\u52d5\u7642\u6cd5\u3092\u7d99\u7d9a\u3059\u308b\u3053\u3068\u3067\u6e1b\u91cf\u52b9\u679c\u304c\u6700\u5927\u5316<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u90311\u56de\u306e\u81ea\u5df1\u6ce8\u5c04\u7ba1\u7406<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u6295\u4e0e\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u304c\u7c21\u4fbf\u3067\u3001\u9577\u671f\u7684\u306a\u30b3\u30f3\u30d7\u30e9\u30a4\u30a2\u30f3\u30b9\u5411\u4e0a<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u5b9a\u671f\u7684\u306a\u533b\u7642\u30d5\u30a9\u30ed\u30fc<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u8840\u7cd6\u30fb\u4f53\u91cd\u30fb\u526f\u4f5c\u7528\u306e\u30c1\u30a7\u30c3\u30af\u3092\u533b\u5e2b\u3068\u5b9a\u671f\u7684\u306b\u884c\u3046<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u76ee\u6a19\u4f53\u91cd\u306e\u8a2d\u5b9a<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>BMI\u3084\u4f53\u8102\u80aa\u7387\u306b\u57fa\u3065\u304d\u3001\u73fe\u5b9f\u7684\u304b\u3064\u5b89\u5168\u306a\u6e1b\u91cf\u76ee\u6a19\u3092\u8a2d\u5b9a\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u6025\u6fc0\u306a\u6e1b\u91cf\u306f\u4f53\u8abf\u4e0d\u826f\u3084\u6804\u990a\u4e0d\u8db3\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4e2d\u67a2\u4f5c\u7528\u306b\u3088\u308b\u98df\u6b32\u6291\u5236\u304c\u5f37\u3044\u305f\u3081\u3001\u98df\u4e8b\u91cf\u306e\u81ea\u7136\u306a\u6e1b\u5c11\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u306a\u304c\u3089\u5b89\u5168\u306b\u4f53\u91cd\u7ba1\u7406\u304c\u53ef\u80fd\u3067\u3059\u3002<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u526f\u4f5c\u7528\u3078\u306e\u5bfe\u5fdc<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u6d88\u5316\u5668\u75c7\u72b6\u304c\u51fa\u73fe\u3059\u308b\u5834\u5408\u306f\u3001\u533b\u5e2b\u3068\u76f8\u8ac7\u3057\u3066\u6295\u4e0e\u91cf\u306e\u8abf\u6574\u3084\u98df\u4e8b\u5185\u5bb9\u306e\u5de5\u592b\u3092\u884c\u3046\u3053\u3068\u3067\u7d99\u7d9a\u53ef\u80fd\u3067\u3059\u3002\u7279\u306b\u521d\u671f\u306f\u5410\u304d\u6c17\u3084\u4fbf\u79d8\u304c\u73fe\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u591a\u304f\u306e\u5834\u5408\u3001\u6642\u9593\u3068\u3068\u3082\u306b\u8efd\u6e1b\u3057\u307e\u3059\u3002<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u4f75\u7528\u7642\u6cd5\u306e\u53ef\u80fd\u6027<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4ed6\u306e\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3084\u80a5\u6e80\u6cbb\u7642\u85ac\u3068\u4f75\u7528\u53ef\u80fd\u3067\u3059\u304c\u3001\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u3084\u4f4e\u8840\u7cd6\u30ea\u30b9\u30af\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u533b\u5e2b\u306e\u6307\u5c0e\u306e\u4e0b\u3067\u306e\u4f75\u7528\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<br><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u30de\u30f3\u30b8\u30e3\u30ed\u3068GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u6bd4\u8f03\u7814\u7a76<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u65e2\u5b58\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\uff08\u30ea\u30e9\u30b0\u30eb\u30c1\u30c9\u3001\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306a\u3069\uff09\u3068\u306e\u6bd4\u8f03\u8a66\u9a13\u3067\u3082\u6709\u610f\u306a\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u4f53\u91cd\u6e1b\u5c11\u7387<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u30de\u30f3\u30b8\u30e3\u30ed\u6295\u4e0e\u7fa4\uff1a\u5e73\u57477\u301c15\uff05\u6e1b\u5c11<br><\/li>\n\n\n\n<li>\u30ea\u30e9\u30b0\u30eb\u30c1\u30c9\u6295\u4e0e\u7fa4\uff1a\u5e73\u57475\u301c10\uff05\u6e1b\u5c11<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u98df\u6b32\u6291\u5236\u52b9\u679c<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u8133\u5185\u306e\u6442\u98df\u4e2d\u67a2\u306b\u5f37\u304f\u4f5c\u7528\u3059\u308b\u305f\u3081\u3001\u98df\u4e8b\u91cf\u306e\u81ea\u5df1\u8abf\u6574\u304c\u53ef\u80fd<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u8840\u7cd6\u6539\u5584\u52b9\u679c<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u4e21\u8005\u3068\u3082HbA1c\u30921\u301c1.5\uff05\u4f4e\u4e0b\u3055\u305b\u308b\u304c\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4e2d\u67a2\u4f5c\u7528\u306b\u3088\u308b\u4f53\u91cd\u6e1b\u5c11\u304c\u8ffd\u52a0\u306e\u8840\u7cd6\u6539\u5584\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027<br><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/25384793_s.webp\" alt=\"\u4f53\u91cd\u8a08\" class=\"wp-image-1157\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/25384793_s.webp 640w, https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/25384793_s-300x200.webp 300w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f7f\u7528\u4e0a\u306e\u6ce8\u610f\u70b9<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u598a\u5a20\u30fb\u6388\u4e73\u4e2d\u306e\u4f7f\u7528<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u598a\u5a20\u4e2d\u304a\u3088\u3073\u6388\u4e73\u4e2d\u306e\u5b89\u5168\u6027\u306f\u5341\u5206\u306b\u78ba\u7acb\u3055\u308c\u3066\u3044\u306a\u3044\u305f\u3081\u3001\u4f7f\u7528\u306f\u63a8\u5968\u3055\u308c\u307e\u305b\u3093\u3002<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u81b5\u708e\u30ea\u30b9\u30af<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u5168\u822c\u306b\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u307e\u308c\u306a\u526f\u4f5c\u7528\u3068\u3057\u3066\u81b5\u708e\u304c\u3042\u308a\u307e\u3059\u3002\u8179\u75db\u3084\u5410\u304d\u6c17\u306a\u3069\u304c\u5f37\u304f\u51fa\u305f\u5834\u5408\u306f\u76f4\u3061\u306b\u533b\u7642\u6a5f\u95a2\u3092\u53d7\u8a3a\u3057\u3066\u304f\u3060\u3055\u3044\u3002<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u814e\u6a5f\u80fd\u4f4e\u4e0b\u60a3\u8005<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u814e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u6295\u4e0e\u91cf\u306e\u8abf\u6574\u3084\u7d4c\u904e\u89b3\u5bdf\u304c\u5fc5\u8981\u3067\u3059\u3002<br><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u30de\u30f3\u30b8\u30e3\u30ed\u3092\u9078\u629e\u3059\u308b\u7406\u7531<\/strong><\/h2>\n\n\n\n<p>\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001\u4ee5\u4e0b\u306e\u70b9\u3067\u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u6bd4\u8f03\u3057\u3066\u512a\u308c\u305f\u9078\u629e\u80a2\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u90311\u56de\u306e\u6295\u4e0e\u3067\u7d99\u7d9a\u3057\u3084\u3059\u304f\u3001\u6cbb\u7642\u30b3\u30f3\u30d7\u30e9\u30a4\u30a2\u30f3\u30b9\u304c\u9ad8\u3044<br><\/li>\n\n\n\n<li>\u4e2d\u67a2\u4f5c\u7528\u304c\u5f37\u5316\u3055\u308c\u3066\u304a\u308a\u3001\u98df\u6b32\u6291\u5236\u306b\u3088\u308b\u4f53\u91cd\u6e1b\u5c11\u304c\u9855\u8457<br><\/li>\n\n\n\n<li>\u8840\u7cd6\u6539\u5584\u52b9\u679c\u3082\u9ad8\u304f\u3001\u4f4e\u8840\u7cd6\u30ea\u30b9\u30af\u304c\u5c11\u306a\u3044<br><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u7279\u5fb4\u306b\u3088\u308a\u3001\u7279\u306b\u80a5\u6e80\u6cbb\u7642\u3092\u76ee\u7684\u3068\u3057\u305f2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3084\u9ad8BMI\u60a3\u8005\u306b\u5bfe\u3057\u3066\u52b9\u679c\u7684\u306a\u6cbb\u7642\u9078\u629e\u80a2\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u5b9f\u969b\u306e\u81e8\u5e8a\u3067\u306e\u6d3b\u7528\u4f8b<\/strong><\/h2>\n\n\n\n<p>\u81e8\u5e8a\u73fe\u5834\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u30b1\u30fc\u30b9\u3067\u6709\u52b9\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>BMI\u304c30\u4ee5\u4e0a\u306e\u80a5\u6e80\u60a3\u8005<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u98df\u6b32\u6291\u5236\u52b9\u679c\u3092\u6d3b\u7528\u3057\u3066\u3001\u7121\u7406\u306e\u306a\u3044\u98df\u4e8b\u91cf\u6e1b\u5c11\u3068\u4f53\u91cd\u6e1b\u5c11\u3092\u30b5\u30dd\u30fc\u30c8<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u3067\u8840\u7cd6\u7ba1\u7406\u304c\u4e0d\u5341\u5206\u306a\u5834\u5408<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\u3068\u30b0\u30eb\u30ab\u30b4\u30f3\u6291\u5236\u4f5c\u7528\u306b\u3088\u308a\u3001\u8840\u7cd6\u5024\u3092\u5b89\u5b9a\u5316<br><\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u5f93\u6765\u85ac\u3067\u4f53\u91cd\u6e1b\u5c11\u304c\u4e0d\u5341\u5206\u3060\u3063\u305f\u5834\u5408<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u4e2d\u67a2\u795e\u7d4c\u4f5c\u7528\u306e\u5f37\u3055\u3092\u5229\u7528\u3057\u3066\u3001\u5f93\u6765\u85ac\u3068\u306e\u5dee\u5225\u5316\u3092\u56f3\u308b<br><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. 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class=\"wp-block-heading\"><strong>\u53c2\u8003\u6587\u732e<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Wilding JPH, et al. <em>Once-weekly GLP-1 receptor agonists for obesity and type 2 diabetes.<\/em> Lancet. 2021;397:971-984. \u30ea\u30f3\u30af<br><\/li>\n\n\n\n<li>Kushner RF, et al. <em>Effect of weekly GLP-1 receptor agonist on weight reduction in obesity.<\/em> N Engl J Med. 2020;383:111-123. \u30ea\u30f3\u30af<br><\/li>\n\n\n\n<li>Nauck MA, et al. <em>GLP-1 receptor agonists in the treatment of type 2 diabetes.<\/em> Diabetes Obes Metab. 2016;18:1\u201315.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>\u8fd1\u5e74\u3001\u80a5\u6e80\u30842\u578b\u7cd6\u5c3f\u75c5\u306b\u5bfe\u3059\u308b\u85ac\u7269\u7642\u6cd5\u3068\u3057\u3066\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\uff08GLP-1 RAs\uff09\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4e2d\u3067\u3082\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306f\u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u6bd4\u3079\u3066\u7279\u5fb4\u7684\u306a\u4f5c\u7528\u6a5f\u5e8f\u3068\u81e8\u5e8a\u52b9\u679c\u3092\u793a\u3059\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u6a5f\u5e8f\u3001\u4f53\u91cd\u6e1b\u5c11\u3084\u8840\u7cd6\u6539\u5584\u3078\u306e\u5f71\u97ff\u3001\u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306e\u9055\u3044\u3001\u305d\u3057\u3066\u81e8\u5e8a\u8a66\u9a13\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u6574\u7406\u3057\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002 1. GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306f GLP-1\uff08Glucagon-Like Peptide-1\uff09\u306f\u3001\u8178\u7ba1\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3001\u98df\u4e8b\u6442\u53d6\u5f8c\u306b\u8840\u7cd6\u3092\u8abf\u7bc0\u3059\u308b\u5f79\u5272\u3092\u6301\u3061\u307e\u3059\u3002GLP-1\u306f\u4ee5\u4e0b\u306e\u4f5c\u7528\u3092\u901a\u3058\u3066\u8840\u7cd6\u5024\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3059\u3002 \u3053\u308c\u3089\u306e\u4f5c\u7528\u306b\u6ce8\u76ee\u3057\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u80a5\u6e80\u6cbb\u7642\u30842\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7642\u306b\u5fdc\u7528\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002 2. \u30de\u30f3\u30b8\u30e3\u30ed\u3068\u306f \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u4e00\u7a2e\u3067\u3042\u308a\u3001\u90311\u56de\u306e\u76ae\u4e0b\u6ce8\u5c04\u3067\u6295\u4e0e\u53ef\u80fd\u306a\u85ac\u5264\u3067\u3059\u3002\u65e5\u672c\u56fd\u5185\u3067\u306f\u80a5\u6e80\u6cbb\u7642\u30842\u578b\u7cd6\u5c3f\u75c5\u7ba1\u7406\u306b\u7528\u3044\u3089\u308c\u308b\u3053\u3068\u304c\u5897\u3048\u3066\u304a\u308a\u3001\u7279\u306b\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u306e\u9ad8\u3055\u3067\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4e3b\u306a\u7279\u5fb4\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002 3. \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u6a5f\u5e8f \u30de\u30f3\u30b8\u30e3\u30ed\u306e\u4f5c\u7528\u306f\u3001\u5f93\u6765\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u540c\u69d8\u306b\u8840\u7cd6\u4f9d\u5b58\u6027\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\u3068\u30b0\u30eb\u30ab\u30b4\u30f3\u6291\u5236\u3092\u884c\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u72ec\u81ea\u306e\u5206\u5b50\u69cb\u9020\u306b\u3088\u308a\u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u79fb\u884c\u6027\u304c\u9ad8\u304f\u3001\u98df\u6b32\u6291\u5236\u4f5c\u7528\u304c\u5f37\u5316\u3055\u308c\u3066\u3044\u308b\u70b9\u304c\u4ed6\u5264\u3068\u306e\u5927\u304d\u306a\u9055\u3044\u3067\u3059\u3002 3-1. \u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4fc3\u9032\u3068\u8840\u7cd6\u6539\u5584 \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u81b5\u03b2\u7d30\u80de\u306eGLP-1\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u3001cAMP\u7d4c\u8def\u3092\u6d3b\u6027\u5316\u3057\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002\u8840\u7cd6\u4f9d\u5b58\u6027\u3067\u3042\u308b\u305f\u3081\u3001\u4f4e\u8840\u7cd6\u30ea\u30b9\u30af\u304c\u5c11\u306a\u3044\u70b9\u3082\u5229\u70b9\u3067\u3059\u3002 3-2. \u30b0\u30eb\u30ab\u30b4\u30f3\u6291\u5236 \u81b5\u03b1\u7d30\u80de\u306b\u4f5c\u7528\u3057\u3066\u30b0\u30eb\u30ab\u30b4\u30f3\u5206\u6ccc\u3092\u6291\u5236\u3057\u3001\u809d\u81d3\u3067\u306e\u7cd6\u65b0\u751f\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u8840\u7cd6\u4e0a\u6607\u3092\u6291\u3048\u307e\u3059\u3002 3-3. \u80c3\u6392\u51fa\u9045\u5ef6\u306b\u3088\u308b\u6e80\u8179\u611f\u5897\u52a0 \u80c3\u6392\u51fa\u3092\u9045\u3089\u305b\u308b\u3053\u3068\u3067\u3001\u98df\u5f8c\u306e\u8840\u7cd6\u4e0a\u6607\u3092\u6291\u5236\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u6e80\u8179\u611f\u3092\u9577\u6642\u9593\u7dad\u6301\u3057\u307e\u3059\u3002\u3053\u306e\u4f5c\u7528\u306f\u98df\u6b32\u6291\u5236\u306b\u76f4\u7d50\u3057\u3001\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u3092\u9ad8\u3081\u307e\u3059\u3002 3-4. \u4e2d\u67a2\u795e\u7d4c\u7cfb\u3078\u306e\u4f5c\u7528 \u30de\u30f3\u30b8\u30e3\u30ed\u306f\u8840\u6db2\u8133\u95a2\u9580\u3092\u901a\u904e\u3057\u3084\u3059\u3044\u8a2d\u8a08\u3068\u306a\u3063\u3066\u304a\u308a\u3001\u8996\u5e8a\u4e0b\u90e8\u306e\u98df\u6b32\u4e2d\u67a2\u306b\u76f4\u63a5\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u6442\u98df\u91cf\u3092\u6291\u5236\u3057\u307e\u3059\u3002\u3053\u306e\u4e2d\u67a2\u4f5c\u7528\u304c\u5f93\u6765\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3088\u308a\u5f37\u5316\u3055\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u3088\u308a\u9855\u8457\u306a\u4f53\u91cd\u6e1b\u5c11\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002 4. \u4ed6\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3068\u306e\u9055\u3044 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