{"id":126,"date":"2025-06-06T03:06:47","date_gmt":"2025-06-06T03:06:47","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/diet\/?p=126"},"modified":"2025-08-12T08:41:17","modified_gmt":"2025-08-12T08:41:17","slug":"why-weight-regain-after-dieting-science","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/diet\/why-weight-regain-after-dieting-science\/","title":{"rendered":"\u306a\u305c\u4f53\u91cd\u306f\u5143\u306b\u623b\u308b\u306e\u304b\uff1f\u2500\u2500\u6e1b\u91cf\u5f8c\u306e\u300c\u30ea\u30d0\u30a6\u30f3\u30c9\u300d\u306b\u6f5c\u3080\u751f\u7269\u5b66\u7684\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u306f"},"content":{"rendered":"\n<p>\u4f53\u91cd\u3092\u6e1b\u3089\u3059\u306e\u306f\u7c21\u5358\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u591a\u304f\u306e\u4eba\u306b\u3068\u3063\u3066\u672c\u5f53\u306e\u96e3\u95a2\u306f\u3001\u305d\u306e\u4f53\u91cd\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u305f\u3068\u3048\u52aa\u529b\u3068\u898f\u5f8b\u306b\u3088\u3063\u3066\u4f53\u91cd\u3092\u843d\u3068\u3057\u305f\u3068\u3057\u3066\u3082\u3001\u307b\u3068\u3093\u3069\u306e\u4eba\u306f\u6570\u5e74\u4ee5\u5185\u306b\u518d\u3073\u4f53\u91cd\u3092\u5897\u3084\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u73fe\u8c61\u306f\u3001\u5358\u306a\u308b\u610f\u5fd7\u306e\u5f31\u3055\u3084\u7fd2\u6163\u306e\u554f\u984c\u3068\u3057\u3066\u7247\u4ed8\u3051\u3089\u308c\u304c\u3061\u3067\u3059\u304c\u3001\u6700\u65b0\u306e\u79d1\u5b66\u7684\u77e5\u898b\u306f\u305d\u3046\u3067\u306f\u306a\u3044\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u79c1\u305f\u3061\u306e\u8eab\u4f53\u306f\u3001\u4f53\u91cd\u6e1b\u5c11\u306b\u5bfe\u3057\u3066\u5f37\u529b\u306b\u62b5\u6297\u3059\u308b\u3088\u3046\u306b\u9032\u5316\u3057\u3066\u304a\u308a\u3001\u305d\u308c\u304c\u4eca\u65e5\u306e\u300c\u30ea\u30d0\u30a6\u30f3\u30c9\u300d\u306e\u6839\u672c\u7684\u306a\u539f\u56e0\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 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class=\"wp-block-heading\">\u6e1b\u91cf\u5f8c\u3001\u4f53\u306e\u4e2d\u3067\u306f\u4f55\u304c\u8d77\u304d\u3066\u3044\u308b\u306e\u304b\uff1f<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. \u30db\u30eb\u30e2\u30f3\u306b\u3088\u308b\u201c\u30a8\u30cd\u30eb\u30ae\u30fc\u5371\u6a5f\u201d\u306e\u30b7\u30b0\u30ca\u30eb<\/h3>\n\n\n\n<p>\u8102\u80aa\u91cf\u304c\u6e1b\u308b\u3068\u3001\u30ec\u30d7\u30c1\u30f3\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u3068\u3044\u3046\u91cd\u8981\u306a\u30db\u30eb\u30e2\u30f3\u306e\u30ec\u30d9\u30eb\u304c\u8457\u3057\u304f\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u4f53\u5185\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u8caf\u8535\u91cf\u3092\u8133\u306b\u4f1d\u3048\u308b\u201c\u71c3\u6599\u8a08\u201d\u306e\u3088\u3046\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul 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class=\"wp-block-list\">\n<li>\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u304c\u9ad8\u307e\u308a\u3001\u7cd6\u306e\u53d6\u308a\u8fbc\u307f\u306f\u826f\u304f\u306a\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u3057\u304b\u3057\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u91cf\u306f\u4f4e\u4e0b\u3057\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\uff08\u7d30\u80de\u5185\u306e\u201c\u767a\u96fb\u6240\u201d\uff09\u306e\u6d3b\u52d5\u3082\u920d\u5316\u3057\u3001\u6d88\u8cbb\u30a8\u30cd\u30eb\u30ae\u30fc\u304c\u6e1b\u308a\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">\u809d\u81d3<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u98df\u4e8b\u91cf\u304c\u5897\u3048\u308b\u3068\u300112\u301c24\u6642\u9593\u4ee5\u5185\u306b\u4e2d\u6027\u8102\u80aa\uff08\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\uff09\u306e\u5408\u6210\u3092\u518d\u958b\u3057\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u3053\u306e\u53cd\u5fdc\u306e\u901f\u3055\u306f\u3001\u6e1b\u91cf\u5f8c\u306e\u4f53\u304c\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u84c4\u3048\u308b\u6e96\u5099\u304c\u3067\u304d\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u306f\u4f53\u304c\u5e38\u306b\u8102\u80aa\u3092\u5408\u6210\u3059\u308b\u80fd\u529b\u3092\u6301\u3063\u3066\u3044\u308b\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u306a\u304f\u3001\u6e1b\u91cf\u5f8c\u306e\u72b6\u614b\u3067\u306f\u7279\u306b\u7d20\u65e9\u304f\u30fb\u512a\u5148\u7684\u306b\u8102\u80aa\u3092\u84c4\u3048\u308b\u3088\u3046\u306b\u306a\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u8102\u80aa\u7d30\u80de<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6e1b\u91cf\u306b\u3088\u308a\u30b5\u30a4\u30ba\u306f\u5c0f\u3055\u304f\u306a\u308a\u307e\u3059\u304c\u3001\u6570\u306f\u6e1b\u308a\u307e\u305b\u3093\u3002<br><\/li>\n\n\n\n<li>\u3088\u308a\u52b9\u7387\u7684\u306b\u6804\u990a\u3092\u53d6\u308a\u8fbc\u3080\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u4e00\u90e8\u3067\u306f\u65b0\u305f\u306a\u8102\u80aa\u7d30\u80de\uff08\u8102\u80aa\u7d30\u80de\u306e\u904e\u5f62\u6210\uff09\u304c\u4f5c\u3089\u308c\u3001\u5c06\u6765\u7684\u306a\u8102\u80aa\u306e\u84c4\u7a4d\u80fd\u529b\u304c\u9ad8\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">\u305d\u306e\u4ed6\u306e\u4f53\u5185\u30b7\u30b9\u30c6\u30e0\u306e\u95a2\u4e0e<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. \u8178\u5185\u30db\u30eb\u30e2\u30f3\u304c\u7a7a\u8179\u611f\u3092\u6301\u7d9a\u3055\u305b\u308b<\/h3>\n\n\n\n<p>\u8178\u306f\u6d88\u5316\u3060\u3051\u3067\u306a\u304f\u3001\u30db\u30eb\u30e2\u30f3\u3092\u5206\u6ccc\u3057\u3066\u8133\u3068\u901a\u4fe1\u3059\u308b\u91cd\u8981\u306a\u5668\u5b98\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u6e1b\u91cf\u5f8c\u306b\u306f\u4ee5\u4e0b\u306e\u6e80\u8179\u30db\u30eb\u30e2\u30f3\u304c\u6e1b\u5c11\u3057\u307e\u3059\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>PYY\uff08\u30da\u30d7\u30c1\u30c9YY\uff09<br><\/li>\n\n\n\n<li>GLP-1\uff08\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9-1\uff09<br><\/li>\n\n\n\n<li>CCK\uff08\u30b3\u30ec\u30b7\u30b9\u30c8\u30ad\u30cb\u30f3\uff09<br><\/li>\n\n\n\n<li>\u30a2\u30df\u30ea\u30f3<br><\/li>\n<\/ul>\n\n\n\n<p>\u305d\u3057\u3066\u3001\u30b0\u30ec\u30ea\u30f3\uff08\u7a7a\u8179\u30db\u30eb\u30e2\u30f3\uff09\u306f\u5897\u52a0\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u5909\u5316\u306f\u6570\u30f6\u6708\u304b\u3089\u6570\u5e74\u306b\u308f\u305f\u3063\u3066\u7d9a\u304f\u3053\u3068\u3082\u3042\u308a\u3001\u6e80\u8179\u611f\u304c\u5f97\u3089\u308c\u306b\u304f\u304f\u3001\u7a7a\u8179\u3092\u611f\u3058\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">2. \u514d\u75ab\u7cfb\u304c\u300c\u80a5\u6e80\u306e\u8a18\u61b6\u300d\u3092\u4fdd\u6301\u3059\u308b<\/h3>\n\n\n\n<p>\u6e1b\u91cf\u3057\u3066\u3082\u3001\u8102\u80aa\u7d44\u7e54\u5185\u306e\u708e\u75c7\u306f\u5b8c\u5168\u306b\u306f\u6d88\u3048\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>T\u7d30\u80de\u306f\u5f15\u304d\u7d9a\u304d\u6d3b\u6027\u5316\u3055\u308c\u3001\u708e\u75c7\u6027\u306e\u74b0\u5883\u3092\u4fdd\u3061\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u7279\u5b9a\u306e\u5358\u7403\uff08CD7+\u30e2\u30ce\u30b5\u30a4\u30c8\u306a\u3069\uff09\u304c\u4f53\u91cd\u7dad\u6301\u3092\u52a9\u3051\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u3053\u308c\u3089\u306e\u5909\u5316\u306f\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\uff08\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u5236\u5fa1\uff09\u306a\u30ec\u30d9\u30eb\u3067\u9577\u304f\u6b8b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">3. \u8178\u5185\u7d30\u83cc\u306e\u5f79\u5272<\/h3>\n\n\n\n<p>\u8178\u5185\u306b\u3044\u308b\u6570\u5146\u500b\u306e\u7d30\u83cc\uff08\u8178\u5185\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30bf\uff09\u306f\u3001\u30ab\u30ed\u30ea\u30fc\u5438\u53ce\u30fb\u98df\u6b32\u5236\u5fa1\u30fb\u708e\u75c7\u8abf\u6574\u306b\u6df1\u304f\u95a2\u308f\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u4f53\u91cd\u3092\u7dad\u6301\u3067\u304d\u3066\u3044\u308b\u4eba\u306f\u3001\u591a\u69d8\u3067\u5b89\u5b9a\u3057\u305f\u8178\u5185\u7d30\u83cc\u3092\u6301\u3064\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u6e1b\u91cf\u671f\u306b\u63a1\u53d6\u3057\u305f\u81ea\u5206\u81ea\u8eab\u306e\u4fbf\u3092\u5f8c\u306b\u623b\u3059\u81ea\u5df1\u7cde\u4fbf\u79fb\u690d\uff08aFMT\uff09\u306b\u3088\u308a\u3001\u4f53\u91cd\u306e\u518d\u5897\u52a0\u304c\u6291\u5236\u3055\u308c\u305f\u3068\u3044\u3046\u7814\u7a76\u3082\u3042\u308a\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">4. \u7b4b\u8089\u91cf\u306e\u6e1b\u5c11\u304c\u518d\u5897\u52a0\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b<\/h3>\n\n\n\n<p>\u7b4b\u8089\uff08\u9664\u8102\u80aa\u4f53\u91cd\uff09\u3092\u591a\u304f\u5931\u3046\u3068\u3001\u57fa\u790e\u4ee3\u8b1d\u304c\u4e0b\u304c\u308a\u3001\u98df\u6b32\u304c\u5897\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u9664\u8102\u80aa\u4f53\u91cd\u306e\u55aa\u5931\u5272\u5408\uff08%FFML\uff09\u304c\u9ad8\u3044\u307b\u3069\u3001\u4f53\u91cd\u306e\u518d\u5897\u52a0\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u30c1\u30eb\u30bc\u30d1\u30c1\u30c9\uff08tirzepatide\uff09\u306a\u3069\u306e\u65b0\u85ac\u306f\u3001\u7b4b\u8089\u3092\u3088\u308a\u826f\u304f\u4fdd\u3064\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u7b4b\u30c8\u30ec\u3068\u5341\u5206\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u6442\u53d6\u306f\u3001\u6e1b\u91cf\u4e2d\u306e\u7b4b\u8089\u7dad\u6301\u306b\u91cd\u8981\u3067\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">\u6cbb\u7642\u3078\u306e\u793a\u5506\uff1a\u751f\u7269\u5b66\u3092\u7406\u89e3\u3057\u3001\u5171\u306b\u50cd\u304f\u5fc5\u8981\u6027<\/h2>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u751f\u7269\u5b66\u7684\u306a\u53cd\u5fdc\u306f\u3001\u300c\u5f31\u3055\u300d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u98e2\u9913\u3092\u9632\u3050\u305f\u3081\u306e\u9032\u5316\u7684\u306a\u9632\u5fa1\u6a5f\u69cb\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u73fe\u4ee3\u3067\u306f\u3053\u308c\u304c\u4f53\u91cd\u306e\u7dad\u6301\u3092\u6975\u3081\u3066\u56f0\u96e3\u306b\u3059\u308b\u8981\u56e0\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u52b9\u679c\u7684\u306a\u4f53\u91cd\u7dad\u6301\u306b\u306f\u3001\u6b21\u306e\u3088\u3046\u306a\u591a\u9762\u7684\u6226\u7565\u304c\u5fc5\u8981\u3067\u3059<\/h3>\n\n\n\n<ul 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class=\"wp-block-heading\">\u5f15\u7528\u6587\u732e<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/doi.org\/10.1152\/ajpregu.00755.2010\">MacLean, Paul S., et al. \u2018Biology\u2019s Response to Dieting: The Impetus for Weight Regain\u2019. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, vol. 301, no. 3, Sept. 2011, pp. R581\u2013600. DOI.org (Crossref), https:\/\/doi.org\/10.1152\/ajpregu.00755.2010.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.ejim.2021.01.002\">Busetto, Luca, et al. \u2018Mechanisms of Weight Regain.\u2019 European Journal of Internal Medicine, vol. 93, Nov. 2021, pp. 3\u20137. DOI.org (Crossref), https:\/\/doi.org\/10.1016\/j.ejim.2021.01.002.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1007\/s13679-025-00619-x\">Van Baak, M.A., Mariman, E.C. Physiology of Weight Regain after Weight Loss: Latest Insights. Curr Obes Rep 14, 28 (2025). https:\/\/doi.org\/10.1007\/s13679-025-00619-x<\/a><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4f53\u91cd\u3092\u6e1b\u3089\u3059\u306e\u306f\u7c21\u5358\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u591a\u304f\u306e\u4eba\u306b\u3068\u3063\u3066\u672c\u5f53\u306e\u96e3\u95a2\u306f\u3001\u305d\u306e\u4f53\u91cd\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u305f\u3068\u3048\u52aa\u529b\u3068\u898f\u5f8b\u306b\u3088\u3063\u3066\u4f53\u91cd\u3092\u843d\u3068\u3057\u305f\u3068\u3057\u3066\u3082\u3001\u307b\u3068\u3093\u3069\u306e\u4eba\u306f\u6570\u5e74\u4ee5\u5185\u306b\u518d\u3073\u4f53\u91cd\u3092\u5897\u3084\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002 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\u30de\u30f3\u30b8\u30e3\u30ed\u3068\u306f\uff1f 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