{"id":1279,"date":"2025-09-26T04:02:24","date_gmt":"2025-09-26T04:02:24","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/diet\/?p=1279"},"modified":"2025-09-26T04:02:25","modified_gmt":"2025-09-26T04:02:25","slug":"diet-without-exercise","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/diet\/diet-without-exercise\/","title":{"rendered":"\u904b\u52d5\u306a\u3057\u3067\u3082\u75e9\u305b\u3089\u308c\u308b\uff1f\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u3067\u53f6\u3048\u308b\u6e1b\u91cf\u6cd5"},"content":{"rendered":"\n<p>\u300c\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u3064\u3089\u3044\u904b\u52d5\u304c\u6b20\u304b\u305b\u306a\u3044\u300d\u2015\u2015\u305d\u3046\u601d\u3044\u8fbc\u3093\u3067\u3044\u307e\u305b\u3093\u304b\uff1f<br>\u5fd9\u3057\u3044\u65e5\u3005\u3092\u9001\u308b\u4e2d\u3067\u3001\u904b\u52d5\u3092\u7d9a\u3051\u308b\u306e\u306f\u73fe\u5b9f\u7684\u306b\u96e3\u3057\u3044\u3068\u3044\u3046\u65b9\u306f\u591a\u3044\u3067\u3057\u3087\u3046\u3002<br>\u3057\u304b\u3057\u3001\u8fd1\u5e74\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u308b\u300c\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u300d\u3067\u306f\u3001<strong>\u904b\u52d5\u306a\u3057\u3067\u3082\u4f53\u91cd\u6e1b\u5c11\u3092\u5b9f\u73fe\u3059\u308b\u65b9\u6cd5<\/strong>\u304c\u78ba\u7acb\u3055\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u672c\u8a18\u4e8b\u3067\u306f\u3001<strong>\u30c0\u30a4\u30a8\u30c3\u30c8\u3000\u904b\u52d5\u306a\u3057<\/strong>\u3067\u6210\u529f\u3092\u76ee\u6307\u3059\u65b9\u306b\u5411\u3051\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u7a2e\u985e\u3084\u30a8\u30d3\u30c7\u30f3\u30b9\u3001\u6ce8\u610f\u70b9\u307e\u3067\u5fb9\u5e95\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u904b\u52d5\u306a\u3057\u3067\u75e9\u305b\u308b\u3053\u3068\u306f\u53ef\u80fd\u304b\uff1f<\/strong><\/h2>\n\n\n\n<p>\u300c\u904b\u52d5\u306a\u3057\u3067\u3082\u75e9\u305b\u3089\u308c\u308b\u306e\u304b\uff1f\u300d\u3068\u3044\u3046\u554f\u3044\u306b\u5bfe\u3059\u308b\u7b54\u3048\u306f\u3001**\u300c\u6761\u4ef6\u3092\u6e80\u305f\u305b\u3070\u53ef\u80fd\u300d**\u3067\u3059\u3002<br>\u5b9f\u969b\u3001\u80a5\u6e80\u6cbb\u7642\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u3082\u3001\u98df\u4e8b\u7642\u6cd5\u3084\u533b\u7642\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u307f\u3067\u306e\u6e1b\u91cf\u306f\u6709\u52b9\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u56fd\u969b\u7684\u306a\u7814\u7a76\u3067\u3082\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u80a5\u6e80\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u98df\u4e8b\u7642\u6cd5\u3060\u3051\u3067\u5e73\u57475\uff5e10%\u306e\u4f53\u91cd\u6e1b\u5c11\u304c\u53ef\u80fd\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<em>\u53c2\u8003\uff1aDiabetes Prevention Program Research Group, 2002<\/em>\uff09\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u8fd1\u5e74\u3067\u306f\u533b\u5e2b\u306e\u7ba1\u7406\u4e0b\u3067\u884c\u3046<strong>GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/strong>\uff08\u4f8b\uff1a\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306a\u3069\uff09\u306e\u6d3b\u7528\u306b\u3088\u308a\u3001\u904b\u52d5\u3092\u4f34\u308f\u305a\u306b\u6e1b\u91cf\u52b9\u679c\u3092\u5f97\u308b\u75c7\u4f8b\u304c\u5897\u3048\u3066\u3044\u307e\u3059\uff08<em>NEJM, 2021<\/em>\uff09\u3002<br>\u2192\u30a8\u30d3\u30c7\u30f3\u30b9\u53c2\u7167<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u904b\u52d5\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u5834\u5408\u3068\u6bd4\u3079\u308b\u3068\u3001\u4ee3\u8b1d\u7dad\u6301\u3084\u7b4b\u8089\u91cf\u4fdd\u6301\u306e\u9762\u3067\u30c7\u30e1\u30ea\u30c3\u30c8\u3082\u3042\u308a\u3001\u5fc5\u305a\u533b\u5e2b\u306e\u6307\u5c0e\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u3068\u306f\uff1f\u7279\u5fb4\u3068\u7a2e\u985e<\/strong><\/h2>\n\n\n\n<p><strong>\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8<\/strong>\u306f\u3001\u533b\u5e2b\u306e\u8a3a\u5bdf\u3068\u533b\u5b66\u7684\u6839\u62e0\u306b\u57fa\u3065\u304f\u6e1b\u91cf\u6cbb\u7642\u306e\u7dcf\u79f0\u3067\u3059\u3002<br>\u300c\u904b\u52d5\u306a\u3057\u3067\u3082\u75e9\u305b\u305f\u3044\u300d\u3068\u3044\u3046\u30cb\u30fc\u30ba\u306b\u5fdc\u3048\u308b\u6cbb\u7642\u3068\u3057\u3066\u3001\u4e3b\u306b\u4ee5\u4e0b\u306e\u65b9\u6cd5\u304c\u7528\u3044\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u5185\u670d\u85ac\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<p>\u80a5\u6e80\u75c7\u306b\u9069\u5fdc\u304c\u3042\u308b\u5185\u670d\u85ac\u3092\u7528\u3044\u308b\u65b9\u6cd5\u3067\u3059\u3002<br>\u4ee3\u8868\u7684\u306a\u3082\u306e\u306f\u6b21\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/strong><strong><br><\/strong> \u98df\u6b32\u6291\u5236\u3068\u80c3\u6392\u51fa\u9045\u5ef6\u4f5c\u7528\u306b\u3088\u308a\u3001\u7121\u7406\u306a\u304f\u6442\u53d6\u30ab\u30ed\u30ea\u30fc\u3092\u6e1b\u3089\u3059\u3002<br>\u6d77\u5916\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u5e73\u574715%\u7a0b\u5ea6\u306e\u4f53\u91cd\u6e1b\u5c11\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>SGLT2\u963b\u5bb3\u85ac<\/strong><strong><br><\/strong> \u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u308b\u304c\u3001\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u3082\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u30aa\u30eb\u30ea\u30b9\u30bf\u30c3\u30c8<\/strong><strong><br><\/strong> \u8102\u80aa\u5438\u53ce\u3092\u6291\u5236\u3057\u3001\u4fbf\u4e2d\u306b\u6392\u51fa\u3055\u305b\u308b\u4f5c\u7528\u304c\u7279\u5fb4\u3002<br><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u30e1\u30c7\u30a3\u30ab\u30eb\u30d5\u30a1\u30b9\u30c6\u30a3\u30f3\u30b0<\/strong><\/h3>\n\n\n\n<p>\u533b\u7642\u6a5f\u95a2\u3067\u7ba1\u7406\u3055\u308c\u305f\u4f4e\u30ab\u30ed\u30ea\u30fc\u30c0\u30a4\u30a8\u30c3\u30c8\uff08VLCD: Very Low Calorie Diet\uff09\u3067\u3059\u3002<br>\u53b3\u5bc6\u306a\u6804\u990a\u7ba1\u7406\u306b\u3088\u308a\u3001\u77ed\u671f\u9593\u3067\u4f53\u91cd\u6e1b\u5c11\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u30e1\u30bd\u30bb\u30e9\u30d4\u30fc\uff08\u8102\u80aa\u6eb6\u89e3\u6ce8\u5c04\uff09<\/strong><\/h3>\n\n\n\n<p>\u76ae\u4e0b\u8102\u80aa\u306b\u85ac\u5264\u3092\u6ce8\u5165\u3057\u3001\u5c40\u6240\u7684\u306a\u8102\u80aa\u5206\u89e3\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002<br>\u90e8\u5206\u75e9\u305b\u306b\u6709\u52b9\u3067\u3001\u904b\u52d5\u306a\u3057\u3067\u30b5\u30a4\u30ba\u30c0\u30a6\u30f3\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4. \u75e9\u8eab\u533b\u7642\u6a5f\u5668<\/strong><\/h3>\n\n\n\n<p>HIFU\u3084\u30af\u30e9\u30a4\u30aa\u30ea\u30dd\u30e9\u30a4\u30b7\u30b9\uff08\u8102\u80aa\u51b7\u5374\u6cbb\u7642\uff09\u306a\u3069\u3001\u76ae\u4e0b\u8102\u80aa\u306b\u7269\u7406\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u884c\u3046\u65b9\u6cd5\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u904b\u52d5\u306a\u3057\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h2>\n\n\n\n<p>\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u4e2d\u3067\u3082\u3001\u7279\u306b<strong>GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac<\/strong>\u306f\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u8c4a\u5bcc\u3067\u3059\u3002<\/p>\n\n\n\n<p>2021\u5e74\u306b\u767a\u8868\u3055\u308c\u305fNEJM\u306e\u5927\u898f\u6a21\u7814\u7a76\u3067\u306f\u3001<strong>\u30bb\u30de\u30b0\u30eb\u30c1\u30c92.4mg\u3092\u90311\u56de\u76ae\u4e0b\u6ce8\u5c04<\/strong>\u3059\u308b\u7fa4\u3067\u3001<strong>\u7d0415%\u306e\u4f53\u91cd\u6e1b\u5c11<\/strong>\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u51fa\u5178\uff1a<br>Wilding JPH, et al. <em>Once-Weekly Semaglutide in Adults with Overweight or Obesity<\/em>. N Engl J Med. 2021;384(11):989-1002.<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u8102\u80aa\u51b7\u5374\u7642\u6cd5\u306b\u3064\u3044\u3066\u306f2015\u5e74\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u3001<strong>\u5e73\u574720%\u7a0b\u5ea6\u306e\u8102\u80aa\u5c64\u6e1b\u5c11<\/strong>\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u51fa\u5178\uff1a<br>Kilmer SL, et al. <em>Cryolipolysis for Noninvasive Fat Reduction<\/em>. Lasers Surg Med. 2014;46(9):712-720.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u904b\u52d5\u306a\u3057\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u30e1\u30ea\u30c3\u30c8\u3068\u6ce8\u610f\u70b9<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30e1\u30ea\u30c3\u30c8<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7d99\u7d9a\u3057\u3084\u3059\u3044<\/strong><strong><br><\/strong> \u904b\u52d5\u7fd2\u6163\u304c\u306a\u304f\u3066\u3082\u53d6\u308a\u7d44\u3081\u308b\u3002<br><\/li>\n\n\n\n<li><strong>\u77ed\u671f\u9593\u3067\u7d50\u679c\u304c\u898b\u3048\u308b<\/strong><strong><br><\/strong> \u85ac\u5264\u3084\u533b\u7642\u6a5f\u5668\u3067\u5373\u52b9\u6027\u304c\u671f\u5f85\u3067\u304d\u308b\u3002<br><\/li>\n\n\n\n<li><strong>\u90e8\u5206\u75e9\u305b\u3082\u53ef\u80fd<\/strong><strong><br><\/strong> \u6ce8\u5c04\u3084\u6a5f\u5668\u3067\u5c40\u6240\u8102\u80aa\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u3067\u304d\u308b\u3002<br><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6ce8\u610f\u70b9<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7b4b\u8089\u91cf\u306e\u6e1b\u5c11\u30ea\u30b9\u30af<\/strong><strong><br><\/strong> \u904b\u52d5\u4e0d\u8db3\u3067\u7b4b\u529b\u4f4e\u4e0b\u3084\u57fa\u790e\u4ee3\u8b1d\u4f4e\u4e0b\u3092\u62db\u304d\u3084\u3059\u3044\u3002<br><\/li>\n\n\n\n<li><strong>\u526f\u4f5c\u7528\u306e\u53ef\u80fd\u6027<\/strong><strong><br><\/strong> \u5185\u670d\u85ac\u30fb\u6ce8\u5c04\u85ac\u306b\u306f\u6d88\u5316\u5668\u75c7\u72b6\u306a\u3069\u306e\u526f\u4f5c\u7528\u304c\u3042\u308b\u3002<br><\/li>\n\n\n\n<li><strong>\u30ea\u30d0\u30a6\u30f3\u30c9<\/strong><strong><br><\/strong> \u4f53\u91cd\u6e1b\u5c11\u5f8c\u306b\u751f\u6d3b\u7fd2\u6163\u304c\u623b\u308b\u3068\u4f53\u91cd\u56de\u5fa9\u3057\u3084\u3059\u3044\u3002<br><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u3069\u3093\u306a\u4eba\u306b\u5411\u3044\u3066\u3044\u308b\uff1f<\/strong><\/h2>\n\n\n\n<p>\u6b21\u306e\u3088\u3046\u306a\u65b9\u306b\u7279\u306b\u6709\u52b9\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5fd9\u3057\u304f\u904b\u52d5\u6642\u9593\u304c\u78ba\u4fdd\u3067\u304d\u306a\u3044\u4eba<\/li>\n\n\n\n<li>\u904b\u52d5\u304c\u82e6\u624b\u30fb\u4f53\u529b\u306b\u4e0d\u5b89\u304c\u3042\u308b\u4eba<\/li>\n\n\n\n<li>\u9ad8\u5ea6\u80a5\u6e80\u3067\u904b\u52d5\u8ca0\u8377\u304c\u9ad8\u3044\u4eba<\/li>\n\n\n\n<li>\u533b\u5e2b\u306e\u7ba1\u7406\u4e0b\u3067\u5b89\u5168\u306b\u75e9\u305b\u305f\u3044\u4eba<\/li>\n<\/ul>\n\n\n\n<p>\u4e00\u65b9\u3001\u57fa\u790e\u75be\u60a3\u304c\u3042\u308b\u65b9\u306f\u614e\u91cd\u306b\u9069\u5fdc\u5224\u65ad\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u6210\u529f\u306e\u30dd\u30a4\u30f3\u30c8<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u306a\u3057\u3067\u3082\u52b9\u679c\u7684\u306b\u75e9\u305b\u308b\u305f\u3081\u306b\u306f\u3001\u6b21\u306e\u30dd\u30a4\u30f3\u30c8\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p><strong>1. \u533b\u5e2b\u306e\u8a3a\u5bdf\u3092\u53d7\u3051\u308b<\/strong><strong><br><\/strong> \u81ea\u5df1\u5224\u65ad\u3067\u6cbb\u7642\u3092\u59cb\u3081\u308b\u306e\u306f\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002\u5fc5\u305a\u5c02\u9580\u533b\u306b\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p><strong>2. \u98df\u4e8b\u7ba1\u7406\u3092\u6020\u3089\u306a\u3044<\/strong><strong><br><\/strong> \u904b\u52d5\u3092\u88dc\u3046\u305f\u3081\u3001\u98df\u4e8b\u7ba1\u7406\u306f\u53b3\u5bc6\u306b\u884c\u3046\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>3. \u4e2d\u9577\u671f\u8a08\u753b\u3092\u7acb\u3066\u308b<\/strong><strong><br><\/strong> \u4e00\u6c17\u306b\u4f53\u91cd\u3092\u843d\u3068\u3059\u3068\u30ea\u30d0\u30a6\u30f3\u30c9\u3057\u3084\u3059\u304f\u3001\u7de9\u3084\u304b\u306a\u6e1b\u91cf\u3092\u76ee\u6307\u3059\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>4. \u5b9a\u671f\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u3092\u53d7\u3051\u308b<\/strong><strong><br><\/strong> \u526f\u4f5c\u7528\u3084\u52b9\u679c\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u6700\u65b0\u52d5\u5411<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u76ee\u899a\u307e\u3057\u3044\u9032\u5316\u3092\u9042\u3052\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u80a5\u6e80\u306f\u5358\u306a\u308b\u7f8e\u5bb9\u4e0a\u306e\u554f\u984c\u3067\u306f\u306a\u304f**\u300c\u6162\u6027\u75be\u60a3\u300d**\u3068\u3057\u3066\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u533b\u5b66\u7684\u306b\u6cbb\u7642\u3059\u3079\u304d\u5bfe\u8c61\u3068\u8a8d\u8b58\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u62e1\u304c\u308a<\/strong><\/h3>\n\n\n\n<p>2020\u5e74\u4ee3\u306b\u5165\u308a\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\uff08\u4f8b\uff1a\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u3001\u30ea\u30e9\u30b0\u30eb\u30c1\u30c9\u306a\u3069\uff09\u306f\u4e16\u754c\u7684\u306b\u80a5\u6e80\u6cbb\u7642\u306e\u4e2d\u5fc3\u306b\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u306e\u85ac\u5264\u306f\u3001\u672c\u6765\u306f2\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3068\u3057\u3066\u958b\u767a\u3055\u308c\u307e\u3057\u305f\u304c\u3001<strong>\u98df\u6b32\u6291\u5236\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u5897\u5927<\/strong>\u306e\u4f5c\u7528\u306b\u3088\u308a\u3001\u80a5\u6e80\u6cbb\u7642\u306b\u3082\u5f37\u3044\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>2021\u5e74\u306e<strong>STEP 1\u8a66\u9a13<\/strong>\uff08Semaglutide Treatment Effect in People with Obesity\uff09\u3067\u306f\u3001\u88ab\u9a13\u8005\u306e86%\u304c5%\u4ee5\u4e0a\u306e\u4f53\u91cd\u6e1b\u5c11\u3092\u9054\u6210\u3057\u300132%\u304c\u4f53\u91cd\u306e20%\u4ee5\u4e0a\u3092\u6e1b\u3089\u3057\u307e\u3057\u305f\uff08NEJM\u8ad6\u6587\uff09\u3002<br>\u2192 \u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u3053\u3061\u3089<\/p>\n\n\n\n<p>\u3053\u306e\u7d50\u679c\u306f\u3001\u904b\u52d5\u306a\u3057\u3067\u3082\u533b\u7642\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u307f\u3067\u9855\u8457\u306a\u4f53\u91cd\u6e1b\u5c11\u304c\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>SGLT2\u963b\u5bb3\u85ac\u306e\u5f79\u5272<\/strong><\/h3>\n\n\n\n<p>SGLT2\u963b\u5bb3\u85ac\uff08\u4f8b\uff1a\u30c0\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u3001\u30a8\u30f3\u30d1\u30b0\u30ea\u30d5\u30ed\u30b8\u30f3\u306a\u3069\uff09\u306f\u3001\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u307e\u3059\u304c\u3001<strong>\u5c3f\u4e2d\u306b\u7cd6\u3092\u6392\u51fa\u3057\u3066\u30a8\u30cd\u30eb\u30ae\u30fc\u640d\u5931\u3092\u8a98\u5c0e\u3059\u308b<\/strong>\u3053\u3068\u3067\u3001\u4f53\u91cd\u6e1b\u5c11\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6b27\u7c73\u306e\u7814\u7a76\u3067\u306f\u3001\u5e73\u5747\u3057\u3066\u7d042\uff5e3kg\u306e\u4f53\u91cd\u6e1b\u5c11\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306b\u6bd4\u3079\u308b\u3068\u6e1b\u91cf\u52b9\u679c\u306f\u7a4f\u3084\u304b\u3067\u3001\u80a5\u6e80\u5358\u72ec\u306e\u5834\u5408\u306f\u4fdd\u967a\u9069\u5fdc\u5916\u3068\u306a\u308b\u30b1\u30fc\u30b9\u304c\u591a\u3044\u305f\u3081\u3001\u533b\u5e2b\u3068\u306e\u76f8\u8ac7\u304c\u5fc5\u9808\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u533b\u7642\u75e9\u8eab\u6a5f\u5668\u3068\u305d\u306e\u6839\u62e0<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u306a\u3057\u3067\u75e9\u305b\u308b\u305f\u3081\u306b\u3001\u533b\u7642\u75e9\u8eab\u6a5f\u5668\u3092\u4f75\u7528\u3059\u308b\u65b9\u6cd5\u3082\u6709\u52b9\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u30af\u30e9\u30a4\u30aa\u30ea\u30dd\u30e9\u30a4\u30b7\u30b9\uff08\u8102\u80aa\u51b7\u5374\u6cbb\u7642\uff09<\/strong><\/h3>\n\n\n\n<p>\u8102\u80aa\u7d30\u80de\u3092\u9078\u629e\u7684\u306b\u51b7\u5374\u3057\u3001\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff08\u7d30\u80de\u6b7b\uff09\u3092\u8a98\u5c0e\u3059\u308b\u6cbb\u7642\u3067\u3059\u30022014\u5e74\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u30011\u56de\u306e\u65bd\u8853\u3067\u5e73\u5747<strong>20%\u7a0b\u5ea6\u306e\u8102\u80aa\u5c64\u539a\u6e1b\u5c11<\/strong>\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059\uff08Lasers Surg Med\u8a8c\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u6280\u8853\u306e\u30e1\u30ea\u30c3\u30c8\u306f\u3001\u76ae\u819a\u3092\u50b7\u3064\u3051\u305a\u306b\u90e8\u5206\u75e9\u305b\u3092\u5b9f\u73fe\u3067\u304d\u308b\u70b9\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u51fa\u5178\uff1a<br>Kilmer SL, et al. <em>Cryolipolysis for Noninvasive Fat Reduction<\/em>. Lasers Surg Med. 2014;46(9):712-720.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. HIFU\uff08\u9ad8\u5bc6\u5ea6\u7126\u70b9\u5f0f\u8d85\u97f3\u6ce2\uff09<\/strong><\/h3>\n\n\n\n<p>\u8d85\u97f3\u6ce2\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u76ae\u4e0b\u8102\u80aa\u5c64\u306b\u96c6\u4e2d\u3055\u305b\u3001\u8102\u80aa\u7d30\u80de\u3092\u7834\u58ca\u3059\u308b\u6cbb\u7642\u3067\u3059\u3002\u6cbb\u7642\u5f8c\u7d043\u30f6\u6708\u3067\u90e8\u5206\u75e9\u305b\u304c\u9855\u5728\u5316\u3057\u3001\u6570cm\u5358\u4f4d\u306e\u30b5\u30a4\u30ba\u30c0\u30a6\u30f3\u3092\u76ee\u6307\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<p>HIFU\u306f\u75db\u307f\u3084\u30c0\u30a6\u30f3\u30bf\u30a4\u30e0\u304c\u6bd4\u8f03\u7684\u5c11\u306a\u304f\u3001\u4ed5\u4e8b\u3084\u80b2\u5150\u3092\u3057\u306a\u304c\u3089\u3067\u3082\u53d7\u3051\u3084\u3059\u3044\u306e\u304c\u7279\u5fb4\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u98df\u4e8b\u7642\u6cd5\u3068\u904b\u52d5\u306a\u3057\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u7d44\u307f\u5408\u308f\u305b<\/strong><\/h2>\n\n\n\n<p>\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306b\u304a\u3044\u3066\u3082\u3001<strong>\u98df\u4e8b\u7642\u6cd5\u306f\u6cbb\u7642\u306e\u6838<\/strong>\u3067\u3059\u3002<br>\u7279\u306b\u904b\u52d5\u306a\u3057\u306e\u5834\u5408\u3001\u7b4b\u8089\u91cf\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306b<strong>\u305f\u3093\u3071\u304f\u8cea\u6442\u53d6\u3092\u5341\u5206\u78ba\u4fdd\u3059\u308b<\/strong>\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>VLCD\uff08Very Low Calorie Diet\uff09<\/strong><\/h3>\n\n\n\n<p>\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u3092\u5fb9\u5e95\u3059\u308b\u65b9\u6cd5\u3068\u3057\u3066\u3001VLCD\uff081\u65e5800kcal\u4ee5\u4e0b\u306e\u98df\u4e8b\u30d7\u30ed\u30b0\u30e9\u30e0\uff09\u304c\u533b\u7642\u6a5f\u95a2\u3067\u5b9f\u65bd\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>VLCD\u306f\u53b3\u683c\u306a\u6804\u990a\u7ba1\u7406\u4e0b\u3067\u306e\u307f\u5b9f\u65bd\u53ef\u80fd\u3067\u3042\u308a\u30016\u30f6\u6708\u3067\u5e73\u574710\uff5e15%\u306e\u4f53\u91cd\u6e1b\u5c11\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\uff08CMAJ, 2006\uff09\u3002<br>\u2192 \u8ad6\u6587\u30ea\u30f3\u30af<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30ea\u30d0\u30a6\u30f3\u30c9\u3092\u9632\u3050\u5de5\u592b<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u306a\u3057\u30c0\u30a4\u30a8\u30c3\u30c8\u6700\u5927\u306e\u8ab2\u984c\u306f<strong>\u30ea\u30d0\u30a6\u30f3\u30c9\u30ea\u30b9\u30af<\/strong>\u3067\u3059\u3002\u4ee5\u4e0b\u3092\u610f\u8b58\u3059\u308b\u3053\u3068\u3067\u518d\u5897\u52a0\u3092\u9632\u304e\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u98df\u4e8b\u65e5\u8a18\u306e\u7fd2\u6163\u5316<br><\/strong> \u4f55\u3092\u3069\u308c\u3060\u3051\u98df\u3079\u305f\u304b\u3092\u5e38\u306b\u8a18\u9332\u3002<\/p>\n\n\n\n<p><strong>\u533b\u5e2b\u30fb\u6804\u990a\u58eb\u306e\u5b9a\u671f\u30d5\u30a9\u30ed\u30fc<br><\/strong> \u884c\u52d5\u5909\u5bb9\u3092\u7dad\u6301\u3059\u308b\u30b5\u30dd\u30fc\u30c8\u3092\u53d7\u3051\u308b\u3002<\/p>\n\n\n\n<p><strong>\u85ac\u5264\u6f38\u6e1b\u30d7\u30e9\u30f3<br><\/strong> \u6cbb\u7642\u7d42\u4e86\u5f8c\u3001\u3044\u304d\u306a\u308a\u85ac\u5264\u3092\u4e2d\u6b62\u305b\u305a\u3001\u8a08\u753b\u7684\u306b\u6e1b\u91cf\u3002<\/p>\n\n\n\n<p><strong>\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406<br><\/strong> \u904e\u98df\u306e\u30c8\u30ea\u30ac\u30fc\u306b\u306a\u308a\u3084\u3059\u3044\u5fc3\u7406\u7684\u8981\u56e0\u3082\u30b1\u30a2\u3059\u308b\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/25384793_s.webp\" alt=\"\u4f53\u91cd\u8a08\" class=\"wp-image-1157\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/25384793_s.webp 640w, https:\/\/www.hiro-clinic.or.jp\/diet\/wp-content\/uploads\/2025\/09\/25384793_s-300x200.webp 300w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30c0\u30a4\u30a8\u30c3\u30c8\u3000\u904b\u52d5\u306a\u3057\u3067\u75e9\u305b\u305f\u3044\u65b9\u3078\u306eQ&amp;A<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Q. \u904b\u52d5\u3092\u5168\u304f\u3057\u306a\u3044\u3068\u7b4b\u8089\u304c\u6e1b\u308a\u307e\u305b\u3093\u304b\uff1f<\/strong><\/h3>\n\n\n\n<p>A. \u306f\u3044\u3002\u904b\u52d5\u306a\u3057\u306e\u6e1b\u91cf\u3067\u306f\u7b4b\u8089\u91cf\u6e1b\u5c11\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u3067\u306f\u305f\u3093\u3071\u304f\u8cea\u6442\u53d6\u3084\u90e8\u5206\u7684\u306aEMS\uff08\u7b4b\u96fb\u6c17\u523a\u6fc0\uff09\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Q. \u4fdd\u967a\u306f\u9069\u7528\u3055\u308c\u307e\u3059\u304b\uff1f<\/strong><\/h3>\n\n\n\n<p>A. \u80a5\u6e80\u75c7\u306b\u5408\u4f75\u75c7\uff08\u9ad8\u8840\u5727\u3001\u7cd6\u5c3f\u75c5\u306a\u3069\uff09\u304c\u3042\u308c\u3070\u3001\u4e00\u90e8\u85ac\u5264\u306f\u4fdd\u967a\u9069\u7528\u3068\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u7f8e\u5bb9\u76ee\u7684\u3067\u306f\u81ea\u7531\u8a3a\u7642\u304c\u57fa\u672c\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>Q. \u3069\u308c\u304f\u3089\u3044\u3067\u7d50\u679c\u304c\u51fa\u307e\u3059\u304b\uff1f<\/strong><\/h3>\n\n\n\n<p>A. \u5185\u670d\u85ac\u6cbb\u7642\u3067\u306f\u7d042\uff5e3\u30f6\u6708\u3067\u4f53\u91cd\u6e1b\u5c11\u304c\u5b9f\u611f\u3067\u304d\u307e\u3059\u3002\u8102\u80aa\u51b7\u5374\u3084HIFU\u306f3\u30f6\u6708\u524d\u5f8c\u3067\u90e8\u5206\u7684\u306b\u30b5\u30a4\u30ba\u30c0\u30a6\u30f3\u304c\u9855\u8457\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u5c02\u9580\u533b\u306b\u76f8\u8ac7\u3059\u308b\u91cd\u8981\u6027<\/strong><\/h2>\n\n\n\n<p>\u300c\u904b\u52d5\u306a\u3057\u3067\u75e9\u305b\u305f\u3044\u300d\u3068\u3044\u3046\u5e0c\u671b\u306f\u3001\u6c7a\u3057\u3066\u7279\u5225\u306a\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u591a\u5fd9\u306a\u73fe\u4ee3\u4eba\u3084\u8eab\u4f53\u7684\u306a\u4e8b\u60c5\u3092\u62b1\u3048\u305f\u65b9\u306b\u3068\u3063\u3066\u3001\u3080\u3057\u308d\u73fe\u5b9f\u7684\u306a\u9078\u629e\u80a2\u3068\u8a00\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u9069\u5207\u306a\u6cbb\u7642\u6cd5\u306e\u9078\u5b9a\u3001\u526f\u4f5c\u7528\u7ba1\u7406\u3001\u30ea\u30d0\u30a6\u30f3\u30c9\u9632\u6b62\u307e\u3067\u4e00\u8cab\u3057\u305f\u8a08\u753b\u304c\u306a\u3051\u308c\u3070\u3001\u671f\u5f85\u3057\u305f\u52b9\u679c\u306f\u5f97\u3089\u308c\u307e\u305b\u3093\u3002\u80a5\u6e80\u306f\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u4e00\u3064\u3067\u3042\u308a\u3001<strong>\u533b\u5b66\u7684\u7ba1\u7406\u306e\u5bfe\u8c61<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u5fc5\u305a\u4fe1\u983c\u3067\u304d\u308b\u533b\u7642\u6a5f\u95a2\u306b\u76f8\u8ac7\u3057\u3001\u3042\u306a\u305f\u306b\u5408\u3063\u305f\u30aa\u30fc\u30c0\u30fc\u30e1\u30a4\u30c9\u30d7\u30e9\u30f3\u3092\u7acb\u3066\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u300c\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u904b\u52d5\u304c\u5fc5\u9808\u300d\u3068\u3044\u3046\u5e38\u8b58\u306f\u3001\u73fe\u4ee3\u533b\u7642\u306e\u9032\u6b69\u306b\u3088\u308a\u5909\u308f\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002<br><strong>\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u3092\u6d3b\u7528\u3059\u308c\u3070\u3001\u904b\u52d5\u306a\u3057\u3067\u3082\u78ba\u304b\u306a\u6e1b\u91cf\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b<\/strong>\u3053\u3068\u304c\u591a\u304f\u306e\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u5b89\u6613\u306a\u81ea\u5df1\u6d41\u306f\u30ea\u30b9\u30af\u3092\u4f34\u3044\u307e\u3059\u3002<br>\u5c02\u9580\u533b\u3068\u76f8\u8ac7\u3057\u3001\u81ea\u5206\u306b\u5408\u3063\u305f\u65b9\u6cd5\u3092\u9078\u3076\u3053\u3068\u304c\u3001\u6700\u3082\u5b89\u5168\u304b\u3064\u52b9\u679c\u7684\u306a\u9053\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u300c\u30c0\u30a4\u30a8\u30c3\u30c8\u3000\u904b\u52d5\u306a\u3057\u300d\u3067\u7406\u60f3\u306e\u4f53\u3092\u76ee\u6307\u3059\u306a\u3089\u3001\u533b\u7642\u306e\u529b\u3092\u6b63\u3057\u304f\u53d6\u308a\u5165\u308c\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u53c2\u8003\u6587\u732e\u30fb\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Wilding JPH, et al. <em>Once-Weekly Semaglutide in Adults with Overweight or Obesity<\/em>. N Engl J Med. 2021;384(11):989-1002.<br><\/li>\n\n\n\n<li>Kilmer SL, et al. <em>Cryolipolysis for Noninvasive Fat Reduction<\/em>. Lasers Surg Med. 2014;46(9):712-720.<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25354126\/\"><br><\/a><\/li>\n\n\n\n<li>Douketis JD, et al. <em>Comparison of Low-Calorie and Very-Low-Calorie Diets for Long-Term Weight Loss<\/em>. CMAJ. 2006;174(2):182-187.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>NEJM \u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u7814\u7a76<br><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25354126\/\">PubMed \u8102\u80aa\u51b7\u5374\u7642\u6cd5\u30ec\u30d3\u30e5\u30fc<br><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.diabetesprevention.nih.gov\/\">Diabetes Prevention Program Research Group<br><\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u300c\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u3064\u3089\u3044\u904b\u52d5\u304c\u6b20\u304b\u305b\u306a\u3044\u300d\u2015\u2015\u305d\u3046\u601d\u3044\u8fbc\u3093\u3067\u3044\u307e\u305b\u3093\u304b\uff1f\u5fd9\u3057\u3044\u65e5\u3005\u3092\u9001\u308b\u4e2d\u3067\u3001\u904b\u52d5\u3092\u7d9a\u3051\u308b\u306e\u306f\u73fe\u5b9f\u7684\u306b\u96e3\u3057\u3044\u3068\u3044\u3046\u65b9\u306f\u591a\u3044\u3067\u3057\u3087\u3046\u3002\u3057\u304b\u3057\u3001\u8fd1\u5e74\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u308b\u300c\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u300d\u3067\u306f\u3001\u904b\u52d5\u306a\u3057\u3067\u3082\u4f53\u91cd\u6e1b\u5c11\u3092\u5b9f\u73fe\u3059\u308b\u65b9\u6cd5\u304c\u78ba\u7acb\u3055\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002 \u672c\u8a18\u4e8b\u3067\u306f\u3001\u30c0\u30a4\u30a8\u30c3\u30c8\u3000\u904b\u52d5\u306a\u3057\u3067\u6210\u529f\u3092\u76ee\u6307\u3059\u65b9\u306b\u5411\u3051\u3001\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u7a2e\u985e\u3084\u30a8\u30d3\u30c7\u30f3\u30b9\u3001\u6ce8\u610f\u70b9\u307e\u3067\u5fb9\u5e95\u89e3\u8aac\u3057\u307e\u3059\u3002 \u904b\u52d5\u306a\u3057\u3067\u75e9\u305b\u308b\u3053\u3068\u306f\u53ef\u80fd\u304b\uff1f \u300c\u904b\u52d5\u306a\u3057\u3067\u3082\u75e9\u305b\u3089\u308c\u308b\u306e\u304b\uff1f\u300d\u3068\u3044\u3046\u554f\u3044\u306b\u5bfe\u3059\u308b\u7b54\u3048\u306f\u3001**\u300c\u6761\u4ef6\u3092\u6e80\u305f\u305b\u3070\u53ef\u80fd\u300d**\u3067\u3059\u3002\u5b9f\u969b\u3001\u80a5\u6e80\u6cbb\u7642\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u3082\u3001\u98df\u4e8b\u7642\u6cd5\u3084\u533b\u7642\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u307f\u3067\u306e\u6e1b\u91cf\u306f\u6709\u52b9\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u56fd\u969b\u7684\u306a\u7814\u7a76\u3067\u3082\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u80a5\u6e80\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u98df\u4e8b\u7642\u6cd5\u3060\u3051\u3067\u5e73\u57475\uff5e10%\u306e\u4f53\u91cd\u6e1b\u5c11\u304c\u53ef\u80fd\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1aDiabetes Prevention Program Research Group, 2002\uff09\u3002 \u3055\u3089\u306b\u3001\u8fd1\u5e74\u3067\u306f\u533b\u5e2b\u306e\u7ba1\u7406\u4e0b\u3067\u884c\u3046GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\uff08\u4f8b\uff1a\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306a\u3069\uff09\u306e\u6d3b\u7528\u306b\u3088\u308a\u3001\u904b\u52d5\u3092\u4f34\u308f\u305a\u306b\u6e1b\u91cf\u52b9\u679c\u3092\u5f97\u308b\u75c7\u4f8b\u304c\u5897\u3048\u3066\u3044\u307e\u3059\uff08NEJM, 2021\uff09\u3002\u2192\u30a8\u30d3\u30c7\u30f3\u30b9\u53c2\u7167 \u305f\u3060\u3057\u3001\u904b\u52d5\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u5834\u5408\u3068\u6bd4\u3079\u308b\u3068\u3001\u4ee3\u8b1d\u7dad\u6301\u3084\u7b4b\u8089\u91cf\u4fdd\u6301\u306e\u9762\u3067\u30c7\u30e1\u30ea\u30c3\u30c8\u3082\u3042\u308a\u3001\u5fc5\u305a\u533b\u5e2b\u306e\u6307\u5c0e\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002 \u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u3068\u306f\uff1f\u7279\u5fb4\u3068\u7a2e\u985e \u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u3001\u533b\u5e2b\u306e\u8a3a\u5bdf\u3068\u533b\u5b66\u7684\u6839\u62e0\u306b\u57fa\u3065\u304f\u6e1b\u91cf\u6cbb\u7642\u306e\u7dcf\u79f0\u3067\u3059\u3002\u300c\u904b\u52d5\u306a\u3057\u3067\u3082\u75e9\u305b\u305f\u3044\u300d\u3068\u3044\u3046\u30cb\u30fc\u30ba\u306b\u5fdc\u3048\u308b\u6cbb\u7642\u3068\u3057\u3066\u3001\u4e3b\u306b\u4ee5\u4e0b\u306e\u65b9\u6cd5\u304c\u7528\u3044\u3089\u308c\u307e\u3059\u3002 1. \u5185\u670d\u85ac\u6cbb\u7642 \u80a5\u6e80\u75c7\u306b\u9069\u5fdc\u304c\u3042\u308b\u5185\u670d\u85ac\u3092\u7528\u3044\u308b\u65b9\u6cd5\u3067\u3059\u3002\u4ee3\u8868\u7684\u306a\u3082\u306e\u306f\u6b21\u306e\u901a\u308a\u3067\u3059\u3002 2. \u30e1\u30c7\u30a3\u30ab\u30eb\u30d5\u30a1\u30b9\u30c6\u30a3\u30f3\u30b0 \u533b\u7642\u6a5f\u95a2\u3067\u7ba1\u7406\u3055\u308c\u305f\u4f4e\u30ab\u30ed\u30ea\u30fc\u30c0\u30a4\u30a8\u30c3\u30c8\uff08VLCD: Very Low Calorie Diet\uff09\u3067\u3059\u3002\u53b3\u5bc6\u306a\u6804\u990a\u7ba1\u7406\u306b\u3088\u308a\u3001\u77ed\u671f\u9593\u3067\u4f53\u91cd\u6e1b\u5c11\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002 3. \u30e1\u30bd\u30bb\u30e9\u30d4\u30fc\uff08\u8102\u80aa\u6eb6\u89e3\u6ce8\u5c04\uff09 \u76ae\u4e0b\u8102\u80aa\u306b\u85ac\u5264\u3092\u6ce8\u5165\u3057\u3001\u5c40\u6240\u7684\u306a\u8102\u80aa\u5206\u89e3\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002\u90e8\u5206\u75e9\u305b\u306b\u6709\u52b9\u3067\u3001\u904b\u52d5\u306a\u3057\u3067\u30b5\u30a4\u30ba\u30c0\u30a6\u30f3\u304c\u53ef\u80fd\u3067\u3059\u3002 4. \u75e9\u8eab\u533b\u7642\u6a5f\u5668 HIFU\u3084\u30af\u30e9\u30a4\u30aa\u30ea\u30dd\u30e9\u30a4\u30b7\u30b9\uff08\u8102\u80aa\u51b7\u5374\u6cbb\u7642\uff09\u306a\u3069\u3001\u76ae\u4e0b\u8102\u80aa\u306b\u7269\u7406\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u884c\u3046\u65b9\u6cd5\u3067\u3059\u3002 \u904b\u52d5\u306a\u3057\u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u30a8\u30d3\u30c7\u30f3\u30b9 \u533b\u7642\u30c0\u30a4\u30a8\u30c3\u30c8\u306e\u4e2d\u3067\u3082\u3001\u7279\u306bGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u8c4a\u5bcc\u3067\u3059\u3002 2021\u5e74\u306b\u767a\u8868\u3055\u308c\u305fNEJM\u306e\u5927\u898f\u6a21\u7814\u7a76\u3067\u306f\u3001\u30bb\u30de\u30b0\u30eb\u30c1\u30c92.4mg\u3092\u90311\u56de\u76ae\u4e0b\u6ce8\u5c04\u3059\u308b\u7fa4\u3067\u3001\u7d0415%\u306e\u4f53\u91cd\u6e1b\u5c11\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002 \u51fa\u5178\uff1aWilding JPH, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021;384(11):989-1002. \u307e\u305f\u3001\u8102\u80aa\u51b7\u5374\u7642\u6cd5\u306b\u3064\u3044\u3066\u306f2015\u5e74\u306e\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u3067\u3001\u5e73\u574720%\u7a0b\u5ea6\u306e\u8102\u80aa\u5c64\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u51fa\u5178\uff1aKilmer SL, et [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":1280,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[156],"tags":[37,159,157,175],"class_list":["post-1279","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-156","tag-37","tag-159","tag-157","tag-175"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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