{"id":1335,"date":"2024-09-05T21:34:10","date_gmt":"2024-09-05T12:34:10","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/ed\/%e3%82%b7%e3%83%ab%e3%83%87%e3%83%8a%e3%83%95%e3%82%a3%e3%83%ab%e3%81%ae%e5%86%85%e6%9c%8d%e4%b8%ad%e3%81%ae%e6%b3%a8%e6%84%8f%e7%82%b9\/"},"modified":"2024-10-11T12:23:42","modified_gmt":"2024-10-11T03:23:42","slug":"%e3%82%b7%e3%83%ab%e3%83%87%e3%83%8a%e3%83%95%e3%82%a3%e3%83%ab%e3%81%ae%e5%86%85%e6%9c%8d%e4%b8%ad%e3%81%ae%e6%b3%a8%e6%84%8f%e7%82%b9","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/ed\/%e3%82%b7%e3%83%ab%e3%83%87%e3%83%8a%e3%83%95%e3%82%a3%e3%83%ab%e3%81%ae%e5%86%85%e6%9c%8d%e4%b8%ad%e3%81%ae%e6%b3%a8%e6%84%8f%e7%82%b9\/","title":{"rendered":"Precautions while taking sildenafil (Viagra)"},"content":{"rendered":"\n<p>Sildenafil (brand name Viagra, etc.) is a medication used to treat erectile dysfunction, but there are several contraindications and combinations that require caution. Some of these are listed below:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Nitrates<\/strong>: concomitant use with nitrates and nitric oxide donors used to treat chest pain can cause a sudden drop in blood pressure. These include nitroglycerin and isosorbide.<\/li>\n\n\n\n<li><strong>Guanylate cyclase stimulants<\/strong>: concomitant use with riociguat can also dangerously lower blood pressure and should be avoided.<\/li>\n\n\n\n<li><strong>Some antibiotics and antifungals<\/strong>: clarithromycin, erythromycin, ketoconazole, itraconazole, etc., these drugs may slow the breakdown of sildenafil in the body and may increase the risk of side effects.<\/li>\n\n\n\n<li><strong>HIV protease inhibitors<\/strong>: Concomitant use with HIV medications such as ritonavir and saquinavir can increase blood levels of sildenafil and increase the risk of side effects.<\/li>\n\n\n\n<li><strong>Alpha-blockers<\/strong>: Combined use with telmisartan or doxazosin, drugs used to treat hypertension and benign prostatic hypertrophy, can intensify the blood pressure lowering effect and cause dizziness or fainting spells.<\/li>\n<\/ol>\n\n\n\n<h3 class=\"wp-block-heading\">What not to do<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Heavy alcohol consumption<\/strong>: Alcohol is a vasodilator and when combined with sildenafil, increases the risk of blood pressure drops.<\/li>\n\n\n\n<li><strong>Driving and hazardous work<\/strong>: Sildenafil can sometimes affect vision or cause dizziness, so you should avoid driving or operating machinery if you experience such side effects.<\/li>\n\n\n\n<li><strong>Heavy Machinery Operation<\/strong>: For the above reasons, care should also be taken when operating heavy machinery.<\/li>\n<\/ul>\n\n\n\n<p>Always follow your doctor&#8217;s instructions when using sildenafil and report any other medications you are taking to your doctor.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sildenafil (brand name Viagra, etc.) is a medication used to treat erectile dysfunction, but there are several contraindications and combinations that require caution. Some of these are listed below: What not to do Always follow your doctor&#8217;s instructions when using sildenafil and report any other medications you are taking to your doctor.<\/p>\n","protected":false},"author":2,"featured_media":2981,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[100],"tags":[60,61,62,63,64,65,79,66],"class_list":{"0":"post-1335","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-treatment_method-en","8":"tag-beginner-en","9":"tag-ed-en","10":"tag-effectiveness-en","11":"tag-erectile_dysfunction-en","12":"tag-improvement-en","13":"tag-treatment-en","14":"tag--en","15":"tag-medication-en","16":"article"},"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/posts\/1335","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/comments?post=1335"}],"version-history":[{"count":2,"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/posts\/1335\/revisions"}],"predecessor-version":[{"id":4538,"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/posts\/1335\/revisions\/4538"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/media\/2981"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/media?parent=1335"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/categories?post=1335"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/ed\/wp-json\/wp\/v2\/tags?post=1335"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}