{"id":197,"date":"2024-03-27T06:14:53","date_gmt":"2024-03-27T06:14:53","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?post_type=disease&p=197"},"modified":"2024-03-27T06:19:44","modified_gmt":"2024-03-27T06:19:44","slug":"als","status":"publish","type":"disease","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/disease\/als\/","title":{"rendered":"\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7 (ALS)"},"content":{"rendered":"\n
Gene<\/td>\u95a2\u9023\u3059\u308b\u8868\u73fe\u578b<\/td>Inheritance<\/td><\/tr>
ALS2<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001\u75d9\u6027\u9ebb\u75fa<\/td>AR<\/td><\/tr>
ANG<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7<\/td>AD<\/td><\/tr>
ATL1<\/td>\u75d9\u6027\u5bfe\u9ebb\u75fa\u3001\u795e\u7d4c\u969c\u5bb3\u3001\u907a\u4f1d\u6027\u611f\u899a<\/td>AD<\/td><\/tr>
BSCL2<\/td>\u30ea\u30dd\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u3001\u5148\u5929\u6027\u5168\u8eab\u6027\u3001\u8133\u75c7\u3001\u9032\u884c\u6027\u3001\u795e\u7d4c\u969c\u5bb3\u3001\u9060\u4f4d\u907a\u4f1d\u904b\u52d5\u3001VA\u578b\u3001\u30b7\u30e3\u30eb\u30b3\u30fc\u30fb\u30de\u30ea\u30fc\u30fb\u30c8\u30a5\u30fc\u30b9\u75c52\u578b\u3001\u30b7\u30eb\u30d0\u30fc\u75c7\u5019\u7fa4\u3001\u30b7\u30eb\u30d0\u30fc\u75d9\u6027\u5bfe\u9ebb\u75fa\u75c7\u5019\u7fa4\u3001\u75d9\u6027\u5bfe\u9ebb\u75fa17<\/td>AD\/AR<\/td><\/tr>
CHCHD10<\/td>\u30df\u30aa\u30d1\u30c1\u30fc\u3001\u5b64\u7acb\u3057\u305f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3001\u524d\u982d\u5074\u982d\u578b\u8a8d\u77e5\u75c7\u304a\u3088\u3073\/\u307e\u305f\u306f\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c72\u3001\u810a\u9ac4\u6027\u7b4b\u840e\u7e2e\u75c7\u3001\u30b8\u30e7\u30fc\u30b1\u30e9\u578b<\/td>AD<\/td><\/tr>
CHMP2B<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001CHMP2B\u95a2\u9023\u3001\u524d\u982d\u5074\u982d\u578b\u8a8d\u77e5\u75c7<\/td>AD<\/td><\/tr>
DCTN1<\/td>\u30da\u30ea\u30fc\u75c7\u5019\u7fa4\u3001\u795e\u7d4c\u969c\u5bb3\u3001\u9060\u4f4d\u90e8\u306e\u907a\u4f1d\u6027\u904b\u52d5\u969c\u5bb3<\/td>AD<\/td><\/tr>
FIG4<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001\u591a\u767a\u6027\u5c0f\u8133\u56de\u75c7\u3001\u4e21\u5074\u5f8c\u982d\u84cb\u9aa8\u3001\u30e6\u30cb\u30b9\u30fb\u30f4\u30a1\u30ed\u30f3\u75c7\u5019\u7fa4\u3001\u30b7\u30e3\u30eb\u30b3\u30fc\u30fb\u30de\u30ea\u30fc\u30fb\u30c8\u30a5\u30fc\u30b9\u75c5<\/td>AD\/AR<\/td><\/tr>
FUS<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001\u672c\u614b\u6027\u632f\u6226<\/td>AD\/AR<\/td><\/tr>
GBE1<\/td>\u30b0\u30ea\u30b3\u30fc\u30b2\u30f3\u8caf\u8535\u75be\u60a3<\/td>AR<\/td><\/tr>
GRN<\/td>TDP43 \u5c01\u5165\u4f53\u3092\u4f34\u3046\u524d\u982d\u5074\u982d\u8449\u5909\u6027\u3001GRN \u95a2\u9023\u3001\u795e\u7d4c\u30bb\u30ed\u30a4\u30c9 \u30ea\u30dd\u30d5\u30b9\u30c1\u30f3\u75c7<\/td>AD\/AR<\/td><\/tr>
HEXA<\/td>\u30c6\u30a4\u30fb\u30b5\u30c3\u30af\u30b9\u75c5\u3001GM2\u30ac\u30f3\u30b0\u30ea\u30aa\u30b7\u30c9\u30fc\u30b7\u30b9\u3001\u30d8\u30ad\u30bd\u30b5\u30df\u30cb\u30c0\u30fc\u30bcA\u6b20\u640d\u75c7<\/td>AR<\/td><\/tr>
HNRNPA1<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001\u65e9\u767a\u6027\u30d1\u30b8\u30a7\u30c3\u30c8\u75c5\u3092\u4f34\u3046\u5c01\u5165\u4f53\u30df\u30aa\u30d1\u30c1\u30fc<\/td>AD<\/td><\/tr>
HSPD1<\/td>\u75d9\u6027\u5bfe\u9ebb\u75fa\u3001\u767d\u8cea\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u3001\u9ac4\u9798\u5f62\u6210\u4e0d\u5168<\/td>AD\/AR<\/td><\/tr>
KIAA0196<\/td>\u75d9\u6027\u5bfe\u9ebb\u75fa\u3001\u30ea\u30c3\u30c1\u30e3\u30fc\u30fb\u30b7\u30f3\u30c4\u30a7\u30eb\u75c7\u5019\u7fa4\uff083C\u75c7\u5019\u7fa4\uff09<\/td>AD\/AR<\/td><\/tr>
KIF5A<\/td>\u75d9\u6027\u5bfe\u9ebb\u75fa<\/td>AD<\/td><\/tr>
MATR3<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7 21<\/td>AD<\/td><\/tr>
OPTN<\/td>\u7dd1\u5185\u969c\u3001\u958b\u653e\u9685\u89d2\u3001\u7dd1\u5185\u969c\u3001\u6b63\u5e38\u7dca\u5f35\u3001\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7 12<\/td>AD<\/td><\/tr>
PFN1<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7 18<\/td>AD<\/td><\/tr>
PRF1<\/td>\u30ea\u30f3\u30d1\u816b\u3001\u975e\u30db\u30b8\u30ad\u30f3\u3001\u518d\u751f\u4e0d\u826f\u6027\u8ca7\u8840\u3001\u6210\u4eba\u767a\u75c7\u3001\u8840\u7403\u8caa\u200b\u200b\u98df\u6027\u30ea\u30f3\u30d1\u7d44\u7e54\u7403\u75c7<\/td>AR<\/td><\/tr>
REEP1<\/td>\u75d9\u6027\u5bfe\u9ebb\u75fa\u3001\u9060\u4f4d\u907a\u4f1d\u6027\u904b\u52d5\u30cb\u30e5\u30fc\u30ed\u30d1\u30b7\u30fc<\/td>AD<\/td><\/tr>
SETX<\/td>\u52d5\u773c\u904b\u52d5\u5931\u884c\u3092\u4f34\u3046\u904b\u52d5\u5931\u8abf\u3001\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001\u82e5\u5e74\u6027\u3001\u810a\u9ac4\u5c0f\u8133\u5931\u8abf\u75c7<\/td>AD\/AR<\/td><\/tr>
SLC52A2<\/td>\u30d6\u30e9\u30a6\u30f3\u30fb\u30f4\u30a3\u30a2\u30ec\u30c3\u30c8\u30fb\u30f4\u30a1\u30f3\u30fb\u30e9\u30fc\u30ec\u75c7\u5019\u7fa4<\/td>AR<\/td><\/tr>
SLC52A3<\/td>\u30d5\u30a1\u30b8\u30aa\u30fb\u30ed\u30f3\u30c7\u75c5\u3001\u30d6\u30e9\u30a6\u30f3\u30fb\u30f4\u30a3\u30a2\u30ec\u30c3\u30c8\u30fb\u30f4\u30a1\u30f3\u30fb\u30e9\u30fc\u30ec\u75c7\u5019\u7fa4<\/td>AR<\/td><\/tr>
SOD1<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001\u5186\u9310\u89d2\u819c<\/td>AD\/AR<\/td><\/tr>
SPAST<\/td>\u75d9\u6027\u5bfe\u9ebb\u75fa<\/td>AD<\/td><\/tr>
SPG11<\/td>\u75d9\u6027\u5bfe\u9ebb\u75fa\u3001\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001\u30b7\u30e3\u30eb\u30b3\u30fc\u30fb\u30de\u30ea\u30fc\u30fb\u30c8\u30a5\u30fc\u30b9\u75c5<\/td>AR<\/td><\/tr>
SPG20<\/td>\u75d9\u6027\u5bfe\u9ebb\u75fa\uff08\u30c8\u30ed\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\uff09<\/td>AR<\/td><\/tr>
SQSTM1<\/td>\u9aa8\u30d1\u30b8\u30a7\u30c3\u30c8\u75c5\u3001\u524d\u982d\u5074\u982d\u578b\u8a8d\u77e5\u75c7\u304a\u3088\u3073\/\u307e\u305f\u306f\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7 3\u3001\u30df\u30aa\u30d1\u30c1\u30fc\u3001\u9060\u4f4d\u3001\u7e01\u306e\u3042\u308b\u7a7a\u80de\u3092\u4f34\u3046\u3001\u904b\u52d5\u5931\u8abf\u3001\u30b8\u30b9\u30c8\u30cb\u30a2\u3001\u304a\u3088\u3073\u8996\u7dda\u9ebb\u75fa\u3092\u4f34\u3046\u795e\u7d4c\u5909\u6027\u3001\u5c0f\u5150\u671f\u767a\u75c7<\/td>AD\/AR<\/td><\/tr>
TARDBP<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7<\/td>AD<\/td><\/tr>
TIA1<\/td>\u30a6\u30a7\u30e9\u30f3\u30c0\u30fc\u9060\u4f4d\u30df\u30aa\u30d1\u30c1\u30fc<\/td>AD<\/td><\/tr>
TUBA4A<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7 22<\/td>AD<\/td><\/tr>
UBQLN2<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7<\/td>XL<\/td><\/tr>
VAPB<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001\u810a\u9ac4\u6027\u7b4b\u840e\u7e2e\u75c7\u3001\u9045\u767a\u6027\u767a\u75c7\u3001\u30d5\u30a3\u30f3\u30b1\u30eb<\/td>AD<\/td><\/tr>
VCP<\/td>\u7b4b\u840e\u7e2e\u6027\u5074\u7d22\u786c\u5316\u75c7\u3001\u65e9\u767a\u6027\u30d1\u30b8\u30a7\u30c3\u30c8\u75c5\u3092\u4f34\u3046\u5c01\u5165\u4f53\u30df\u30aa\u30d1\u30c1\u30fc\u3001\u30b7\u30e3\u30eb\u30b3\u30fc\u30fb\u30de\u30ea\u30fc\u30fb\u30c8\u30a5\u30fc\u30b9\u75c5<\/td>AD<\/td><\/tr><\/tbody><\/table><\/figure>\n

\u8a73\u3057\u304f\u306f \u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af\u5168\u56fd\u306e\u30af\u30ea\u30cb\u30c3\u30af\u4e00\u89a7<\/a> \u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>","protected":false},"featured_media":0,"template":"template-disease.php","disease-category":[3],"class_list":["post-197","disease","type-disease","status-publish","hentry","disease-category-mental"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/disease\/197","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/disease"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/types\/disease"}],"version-history":[{"count":1,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/disease\/197\/revisions"}],"predecessor-version":[{"id":198,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/disease\/197\/revisions\/198"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media?parent=197"}],"wp:term":[{"taxonomy":"disease-category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/disease-category?post=197"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}