{"id":17507,"date":"2026-01-22T06:17:09","date_gmt":"2026-01-22T06:17:09","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?post_type=genetic-screening&#038;p=17507"},"modified":"2026-01-22T06:17:09","modified_gmt":"2026-01-22T06:17:09","slug":"trisomy-9p-syndrome","status":"publish","type":"genetic-screening","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/genetic-screening\/trisomy-9p-syndrome\/","title":{"rendered":"Trisomy 9p syndrome"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u5225\u540d\u30fb\u95a2\u9023\u75be\u60a3\u540d<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>9p\u91cd\u8907\u75c7\u5019\u7fa4\uff089p duplication syndrome\uff09<\/strong><\/li>\n\n\n\n<li><strong>9p\u90e8\u5206\u30c8\u30ea\u30bd\u30df\u30fc\uff08Partial trisomy 9p\uff09<\/strong><\/li>\n\n\n\n<li><strong>9\u756a\u67d3\u8272\u4f53\u77ed\u8155\u30c8\u30ea\u30bd\u30df\u30fc<\/strong><\/li>\n\n\n\n<li><strong>\u30ec\u30c1\u30e5\u30f3\u75c7\u5019\u7fa4\uff08Rethor\u00e9 syndrome\uff09<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u203b1970\u5e74\u306b\u672c\u75c7\u5019\u7fa4\u3092\u521d\u3081\u3066\u8a73\u7d30\u306b\u5831\u544a\u3057\u305f\u30d5\u30e9\u30f3\u30b9\u306e\u907a\u4f1d\u5b66\u8005\u3001Marie-Odile Rethor\u00e9\u535a\u58eb\u306b\u3061\u306a\u3093\u3067\u540d\u4ed8\u3051\u3089\u308c\u307e\u3057\u305f\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u95a2\u9023\uff1a9p\u5fae\u5c0f\u91cd\u8907\u75c7\u5019\u7fa4\uff089p microduplication syndrome\uff09<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u203b9p24.3\u9818\u57df\u30849p13.1\u9818\u57df\u306a\u3069\u3001\u7279\u5b9a\u306e\u72ed\u3044\u7bc4\u56f2\u306b\u9650\u5b9a\u3055\u308c\u305f\u91cd\u8907\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u5bfe\u8c61\u67d3\u8272\u4f53\u9818\u57df<\/strong><\/h2>\n\n\n\n<p><strong>9\u756a\u67d3\u8272\u4f53 \u77ed\u8155\uff08p\uff09\u5168\u4f53\u3001\u307e\u305f\u306f 9p11\u304b\u3089\u672b\u7aef\uff08pter\uff09\u306b\u304b\u3051\u3066\u306e\u9818\u57df<\/strong><\/p>\n\n\n\n<p>\u672c\u75c7\u5019\u7fa4\u306f\u30019\u756a\u67d3\u8272\u4f53\u306e\u77ed\u8155\uff08p\uff09\u90e8\u5206\u304c\u901a\u5e38\u3088\u308a\u30821\u3064\u591a\u304f\u3001\u7d30\u80de\u5185\u306b\u5408\u8a083\u3064\u5b58\u5728\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u767a\u75c7\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3010\u30b2\u30ce\u30e0\u4e0a\u306e\u8a73\u7d30\u3068\u75c5\u614b\u30e1\u30ab\u30cb\u30ba\u30e0\u3011<\/p>\n\n\n\n<p>9\u756a\u67d3\u8272\u4f53\u77ed\u8155\u306b\u306f\u3001\u8133\u306e\u767a\u9054\u3001\u9854\u9762\u304a\u3088\u3073\u9aa8\u683c\u306e\u5f62\u6210\u3001\u6027\u5206\u5316\u306b\u95a2\u308f\u308b\u91cd\u8981\u306a\u907a\u4f1d\u5b50\u304c\u5bc6\u96c6\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8cac\u4efb\u9818\u57df:<\/strong> \u591a\u304f\u306e\u7814\u7a76\u306b\u3088\u308a\u3001<strong>9p22\u9818\u57df\u304b\u30899p24\u9818\u57df<\/strong>\uff08\u672b\u7aef\u306b\u8fd1\u3044\u90e8\u5206\uff09\u306e\u91cd\u8907\u304c\u3001\u672c\u75c7\u5019\u7fa4\u306b\u7279\u6709\u306e\u77e5\u7684\u969c\u5bb3\u3084\u7279\u5fb4\u7684\u306a\u9854\u8c8c\u306b\u6700\u3082\u5f37\u304f\u5bc4\u4e0e\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u4e3b\u8981\u306a\u95a2\u4e0e\u907a\u4f1d\u5b50\uff08\u4f8b\uff09:<\/strong>\n<ul class=\"wp-block-list\">\n<li><strong>DMRT1 \/ DMRT2 (9p24.3):<\/strong> \u6027\u6c7a\u5b9a\u3084\u767a\u9054\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u91cd\u8907\u306f\u6027\u5206\u5316\u306e\u7570\u5e38\u306b\u95a2\u9023\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>SMARCA2 (9p24.2):<\/strong> \u795e\u7d4c\u767a\u9054\u306b\u95a2\u9023\u3059\u308b\u30af\u30ed\u30de\u30c1\u30f3\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u56e0\u5b50\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>GLDC (9p24.1):<\/strong> \u30b0\u30ea\u30b7\u30f3\u4ee3\u8b1d\u306b\u95a2\u308f\u308a\u3001\u795e\u7d4c\u5b66\u7684\u75c7\u72b6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u907a\u4f1d\u5b50\u91cf\u52b9\u679c:<\/strong> \u67d3\u8272\u4f53\u306e<strong>\u5fae\u5c0f<\/strong>\u306a\u91cd\u8907\u3067\u3042\u3063\u3066\u3082\u3001\u542b\u307e\u308c\u308b\u907a\u4f1d\u5b50\u304c\u300c1.5\u500d\u300d\u5b58\u5728\u3059\u308b\u3053\u3068\u3067\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7523\u751f\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u3001\u80ce\u5150\u671f\u306e\u7d44\u7e54\u5206\u5316\u3084\u795e\u7d4c\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u69cb\u7bc9\u306b\u30a8\u30e9\u30fc\u304c\u751f\u3058\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u767a\u751f\u983b\u5ea6<\/strong><\/h2>\n\n\n\n<p><strong>\u51fa\u751f\u5150 30,000\u4eba \u301c 50,000\u4eba\u306b1\u4eba<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u983b\u5ea6:<\/strong> \u6bd4\u8f03\u7684\u7a00\u306a\u67d3\u8272\u4f53\u7570\u5e38\u3067\u3059\u304c\u3001\u5e38\u67d3\u8272\u4f53\u306e\u90e8\u5206\u30c8\u30ea\u30bd\u30df\u30fc\uff08\u67d3\u8272\u4f53\u306e\u4e00\u90e8\u304c\u91cd\u8907\u3059\u308b\u30bf\u30a4\u30d7\uff09\u306e\u4e2d\u3067\u306f\u30014p\u30c8\u30ea\u30bd\u30df\u30fc\u308410p\u30c8\u30ea\u30bd\u30df\u30fc\u3068\u4e26\u3093\u3067\u3001\u6bd4\u8f03\u7684\u5831\u544a\u6570\u304c\u591a\u3044\u75be\u60a3\u306e\u4e00\u3064\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u8a3a\u65ad\u306e\u73fe\u72b6:<\/strong> \u4ee5\u524d\u306f\u67d3\u8272\u4f53\u5206\u67d3\u6cd5\uff08G\u30d0\u30f3\u30c9\u6cd5\uff09\u3067\u5927\u304d\u306a\u91cd\u8907\u306e\u307f\u304c\u7279\u5b9a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u73fe\u5728\u306f\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u67d3\u8272\u4f53\u691c\u67fb\uff08CMA\uff09\u306e\u666e\u53ca\u306b\u3088\u308a\u3001\u5916\u898b\u7684\u306a\u7279\u5fb4\u304c\u8efd\u5fae\u306a<strong>\u5fae\u5c0f<\/strong>\u91cd\u8907\u306e\u75c7\u4f8b\u3082\u6b63\u78ba\u306b\u8a3a\u65ad\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u6027\u5dee:<\/strong> \u6027\u5225\u306b\u3088\u308b\u983b\u5ea6\u306e\u5dee\u306f\u306a\u304f\u3001\u7537\u5973\u3068\u3082\u306b\u767a\u75c7\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u81e8\u5e8a\u7684\u7279\u5fb4\uff08\u75c7\u72b6\uff09<\/strong><\/h2>\n\n\n\n<p>Trisomy 9p syndrome\u306e\u75c7\u72b6\u306f\u591a\u7cfb\u7d71\u306b\u308f\u305f\u308a\u3001\u8eab\u4f53\u7684\u7279\u5fb4\u3001\u77e5\u7684\u767a\u9054\u3001\u9aa8\u683c\u7570\u5e38\u306e3\u3064\u306e\u5074\u9762\u3067\u9855\u8457\u306a\u6240\u898b\u304c\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>1. \u7279\u5fb4\u7684\u306a\u9854\u8c8c\uff08Facial Features\uff09<\/strong><\/p>\n\n\n\n<p>\u8a3a\u65ad\u306e\u793a\u5506\u3068\u306a\u308b\u975e\u5e38\u306b\u7279\u7570\u7684\u306a\u9854\u7acb\u3061\u304c\u898b\u3089\u308c\u3001\u6210\u9577\u3068\u3068\u3082\u306b\u7279\u5fb4\u304c\u306f\u3063\u304d\u308a\u3057\u3066\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u773c\u7403\u9665\u51f9\uff08Enophthalmos\uff09:<\/strong> \u76ee\u304c\u5965\u307e\u3063\u3066\u3044\u308b\u3088\u3046\u306b\u898b\u3048\u307e\u3059\u3002\u3053\u308c\u306f\u672c\u75c7\u5019\u7fa4\u306b\u975e\u5e38\u306b\u7279\u5fb4\u7684\u306a\u6240\u898b\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u773c\u9593\u958b\u96e2:<\/strong> \u4e21\u76ee\u306e\u9593\u9694\u304c\u5e83\u304f\u96e2\u308c\u3066\u3044\u308b\uff08Hypertelorism\uff09\u3002<\/li>\n\n\n\n<li><strong>\u773c\u77bc\u88c2\u659c\u4e0b:<\/strong> \u76ee\u5c3b\u304c\u4e0b\u304c\u3063\u3066\u3044\u308b\uff08Antimongoloid slant\uff09\u3002<\/li>\n\n\n\n<li><strong>\u9f3b:<\/strong> \u9f3b\u6839\u90e8\u304c\u5e73\u5766\u3067\u3001\u9f3b\u5148\u304c\u5927\u304d\u304f\u4e38\u3044\uff08\u7403\u72b6\u306e\u9f3b\uff09\u3002<\/li>\n\n\n\n<li><strong>\u53e3:<\/strong> \u53e3\u89d2\u304c\u4e0b\u304c\u3063\u3066\u304a\u308a\u3001\u5f13\u72b6\u306e\u8584\u3044\u4e0a\u5507\uff08\u30c6\u30f3\u30c8\u72b6\u4e0a\u5507\uff09\u3092\u5448\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u8033:<\/strong> \u4f4e\u4f4d\u4ed8\u7740\u8033\uff08\u8033\u306e\u4f4d\u7f6e\u304c\u4f4e\u3044\uff09\u3001\u3042\u308b\u3044\u306f\u8033\u4ecb\u304c\u5927\u304d\u304f\u7a81\u51fa\u3057\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>2. \u795e\u7d4c\u767a\u9054\u3068\u77e5\u80fd<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u77e5\u7684\u969c\u5bb3:<\/strong> \u307b\u307c\u3059\u3079\u3066\u306e\u75c7\u4f8b\u3067\u3001\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u77e5\u7684\u767a\u9054\u306e\u9045\u308c\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u8a00\u8a9e\u767a\u9054\u306e\u8457\u3057\u3044\u9045\u308c:<\/strong> \u904b\u52d5\u767a\u9054\u306b\u6bd4\u3079\u3066\u3082\u3001\u7279\u306b\u8a00\u8449\u306e\u7372\u5f97\uff08\u8868\u51fa\u8a00\u8a9e\uff09\u306b\u5f37\u3044\u9045\u308c\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u7b4b\u7dca\u5f35\u306e\u7570\u5e38:<\/strong> \u4e73\u5150\u671f\u306b\u306f\u7b4b\u7dca\u5f35\u4f4e\u4e0b\uff08\u4f4e\u7dca\u5f35\uff09\u304c\u898b\u3089\u308c\u3001\u6210\u9577\u3068\u3068\u3082\u306b\u4e00\u90e8\u3067\u7b4b\u7dca\u5f35\u4ea2\u9032\uff08\u75d9\u6027\uff09\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u884c\u52d5\u7279\u6027:<\/strong> \u591a\u52d5\u6027\u3084\u81ea\u9589\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u75c7\u7684\u306a\u7279\u6027\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>3. \u6307\u304a\u3088\u3073\u9aa8\u683c\u306e\u7570\u5e38<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6307\u306e\u5f62\u6210\u4e0d\u5168:<\/strong> \u89aa\u6307\u304c\u77ed\u304f\u3001\u4f4d\u7f6e\u304c\u305a\u308c\u3066\u3044\u308b\uff08\u4f4e\u4f4d\u4ed8\u7740\u6bcd\u6307\uff09\u3002\u307e\u305f\u3001\u6307\u306e\u5148\u7aef\u306e\u7bc0\uff08\u672b\u7bc0\u9aa8\uff09\u304c\u77ed\u3044\u3053\u3068\u304c\u591a\u304f\u3001\u722a\u304c\u672a\u767a\u9054\uff08\u722a\u4f4e\u5f62\u6210\uff09\u3067\u3042\u308b\u3053\u3068\u3082\u7279\u5fb4\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u733f\u7dda:<\/strong> \u624b\u306e\u3072\u3089\u3092\u6a2a\u5207\u308b\u4e00\u672c\u306e\u592a\u3044\u3057\u308f\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u9aa8\u5e74\u9f62\u306e\u9045\u308c:<\/strong> \u9aa8\u306e\u6210\u9577\u304c\u5b9f\u5e74\u9f62\u3088\u308a\u3082\u9045\u308c\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u810a\u67f1\u5074\u5f2f\u75c7:<\/strong> \u7b4b\u8089\u306e\u30d0\u30e9\u30f3\u30b9\u3084\u9aa8\u683c\u306e\u5f71\u97ff\u3067\u3001\u6210\u9577\u3068\u3068\u3082\u306b\u80cc\u9aa8\u304c\u66f2\u304c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>4. \u5185\u90e8\u5947\u5f62\u304a\u3088\u3073\u305d\u306e\u4ed6\u306e\u5408\u4f75\u75c7<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5c0f\u982d\u75c7:<\/strong> \u8133\u306e\u5bb9\u7a4d\u304c\u76f8\u5bfe\u7684\u306b\u5c0f\u3055\u304f\u3001\u982d\u56f2\u304c\u6a19\u6e96\u3092\u4e0b\u56de\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u5148\u5929\u6027\u5fc3\u75be\u60a3\uff08\u7d0410\u301c20%\uff09:<\/strong> \u983b\u5ea6\u306f\u9ad8\u304f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u5fc3\u5ba4\u4e2d\u9694\u6b20\u640d\uff08VSD\uff09\u306a\u3069\u306e\u5408\u4f75\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u6ccc\u5c3f\u751f\u6b96\u5668\u7570\u5e38:<\/strong> \u814e\u5947\u5f62\u3084\u3001\u7537\u5150\u306b\u304a\u3051\u308b\u505c\u7559\u7cbe\u5de3\u3001\u5c3f\u9053\u4e0b\u88c2\u3002<\/li>\n\n\n\n<li><strong>\u6210\u9577\u4e0d\u5168:<\/strong> \u51fa\u751f\u6642\u3088\u308a\u4f53\u683c\u304c\u5c0f\u3055\u304f\u3001\u51fa\u751f\u5f8c\u3082\u8eab\u9577\u30fb\u4f53\u91cd\u306e\u5897\u52a0\u304c\u3086\u3063\u304f\u308a\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u539f\u56e0<\/strong><\/h2>\n\n\n\n<p><strong>9p\u9818\u57df\u306e\u91cd\u8907\uff08\u4e0d\u5747\u8861\u8ee2\u5ea7\u307e\u305f\u306f\u65b0\u751f\u7a81\u7136\u5909\u7570\uff09<\/strong><\/p>\n\n\n\n<p>9p\u30c8\u30ea\u30bd\u30df\u30fc\u304c\u751f\u3058\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u306f\u3001\u4e3b\u306b\u4ee5\u4e0b\u306e\u30d1\u30bf\u30fc\u30f3\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>1. \u89aa\u306e\u5747\u8861\u578b\u8ee2\u5ea7\u304b\u3089\u306e\u7d99\u627f\uff08\u7d0460\u301c70%\uff09<\/strong><\/p>\n\n\n\n<p>\u6700\u3082\u4e00\u822c\u7684\u306a\u539f\u56e0\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30e1\u30ab\u30cb\u30ba\u30e0:<\/strong> \u4e21\u89aa\u306e\u3069\u3061\u3089\u304b\u304c\u300c\u5747\u8861\u578b\u8ee2\u5ea7\uff08\u67d3\u8272\u4f53\u306e\u4e00\u90e8\u304c\u5165\u308c\u66ff\u308f\u3063\u3066\u3044\u308b\u304c\u3001\u91cf\u306f\u6b63\u5e38\u306a\u306e\u3067\u672c\u4eba\u306f\u5065\u5eb7\uff09\u300d\u306e\u4fdd\u56e0\u8005\u3067\u3042\u308b\u5834\u5408\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u4e0d\u5747\u8861\u8ee2\u5ea7:<\/strong> \u6e1b\u6570\u5206\u88c2\u306e\u969b\u306b\u30019p\u306e\u65ad\u7247\u304c\u4f59\u5206\u306b\u542b\u307e\u308c\u305f\u67d3\u8272\u4f53\u304c\u53d7\u7cbe\u5375\u306b\u53d7\u3051\u7d99\u304c\u308c\u308b\u3068\u30019p\u30c8\u30ea\u30bd\u30df\u30fc\u304c\u751f\u3058\u307e\u3059\u3002\u3053\u306e\u5834\u5408\u3001\u5225\u306e\u67d3\u8272\u4f53\u306e\u672b\u7aef\u90e8\u5206\u304c\u300c\u6b20\u5931\uff08\u30e2\u30ce\u30bd\u30df\u30fc\uff09\u300d\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u75c7\u72b6\u304c\u3088\u308a\u8907\u96d1\u5316\u3059\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>2. \u65b0\u751f\u7a81\u7136\u5909\u7570\uff08De novo\uff09<\/strong><\/p>\n\n\n\n<p>\u89aa\u306e\u67d3\u8272\u4f53\u69cb\u6210\u306f\u6b63\u5e38\u3067\u3042\u308a\u3001\u53d7\u7cbe\u306e\u904e\u7a0b\u3001\u3042\u308b\u3044\u306f\u53d7\u7cbe\u5375\u304c\u5206\u88c2\u3059\u308b\u521d\u671f\u6bb5\u968e\u3067\u5076\u7136\u306b9p\u306e\u91cd\u8907\u304c\u751f\u3058\u308b\u30b1\u30fc\u30b9\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7b49\u8155\u67d3\u8272\u4f539p [i(9p)]:<\/strong> 9\u756a\u67d3\u8272\u4f53\u304c\u4e2d\u5fc3\u4f53\u3067\u6a2a\u306b\u5272\u308c\u3001\u77ed\u8155\uff08p\uff09\u3060\u3051\u30922\u3064\u6301\u3064\u7b49\u8155\u67d3\u8272\u4f53\u304c\u5f62\u6210\u3055\u308c\u308b\u30bf\u30a4\u30d7\u306a\u3069\u304c\u542b\u307e\u308c\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u5fae\u5c0f\u91cd\u8907:<\/strong> 9p\u9818\u57df\u5185\u306e\u7d44\u63db\u3048\u30a8\u30e9\u30fc\u306b\u3088\u308a\u3001\u5076\u7136\u306b<strong>\u5fae\u5c0f<\/strong>\u306a\u91cd\u8907\u304c\u751f\u3058\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a3a\u65ad\u65b9\u6cd5<\/strong><\/h2>\n\n\n\n<p>\u81e8\u5e8a\u7684\u306a\u9854\u8c8c\u3084\u6307\u306e\u7570\u5e38\u3001\u767a\u9054\u9045\u6ede\u304b\u3089\u672c\u75c7\u5019\u7fa4\u3092\u7591\u3044\u3001\u67d3\u8272\u4f53\u30fb\u30b2\u30ce\u30e0\u691c\u67fb\u3067\u78ba\u5b9a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u67d3\u8272\u4f53\u6838\u578b\u5206\u6790\uff08G\u30d0\u30f3\u30c9\u6cd5\uff09:<br>\u9855\u5fae\u93e1\u4e0b\u3067\u67d3\u8272\u4f53\u306e\u6570\u3068\u5f62\u3092\u8abf\u3079\u30019\u756a\u67d3\u8272\u4f53\u306e\u77ed\u8155\u304c\u9577\u3044\u3001\u3042\u308b\u3044\u306f\u4f59\u5206\u306a\u67d3\u8272\u4f53\u65ad\u7247\u304c\u3042\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li>\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u67d3\u8272\u4f53\u691c\u67fb\uff08CMA\uff09:<br>\u78ba\u5b9a\u8a3a\u65ad\u306e\u30b4\u30fc\u30eb\u30c9\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\u3067\u3059\u30029p\u9818\u57df\u306e\u3069\u306e\u7bc4\u56f2\u304c\u3001\u3069\u306e\u7a0b\u5ea6\u306e\u30b5\u30a4\u30ba\uff08\u5fae\u5c0f\u91cd\u8907\u306e\u7bc4\u56f2\uff09\u3067\u91cd\u8907\u3057\u3066\u3044\u308b\u304b\u3092\u7cbe\u5bc6\u306b\u7279\u5b9a\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li>FISH\u6cd5:<br>9p\u7279\u7570\u7684\u306a\u30d7\u30ed\u30fc\u30d6\uff08\u86cd\u5149\u6a19\u8b58\uff09\u3092\u7528\u3044\u3066\u30019p\u9818\u57df\u306e\u30b3\u30d4\u30fc\u6570\u304c3\u3064\u5b58\u5728\u3059\u308b\u3053\u3068\u3092\u8996\u899a\u7684\u306b\u8a3c\u660e\u3057\u307e\u3059\u3002\u89aa\u306e\u4fdd\u56e0\u72b6\u614b\uff08\u8ee2\u5ea7\u306e\u6709\u7121\uff09\u3092\u78ba\u8a8d\u3059\u308b\u969b\u306b\u3082\u91cd\u8981\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u753b\u50cf\u8a3a\u65ad:<\/strong>\n<ul class=\"wp-block-list\">\n<li><strong>\u982d\u90e8MRI:<\/strong> \u8133\u306e\u69cb\u9020\u7570\u5e38\u3092\u8a55\u4fa1\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u624b\u8db3\u306eX\u7dda:<\/strong> \u6307\u306e\u9aa8\uff08\u672b\u7bc0\u9aa8\uff09\u306e\u5f62\u6210\u72b6\u614b\u3084\u9aa8\u5e74\u9f62\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u5fc3\u30a8\u30b3\u30fc\u30fb\u8179\u90e8\u30a8\u30b3\u30fc:<\/strong> \u5185\u90e8\u5947\u5f62\u306e\u691c\u7d22\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u6cbb\u7642\u65b9\u6cd5<\/strong><\/h2>\n\n\n\n<p>\u73fe\u4ee3\u306e\u533b\u5b66\u306b\u304a\u3044\u3066\u3001\u904e\u5270\u306a\u67d3\u8272\u4f53\u3092\u6b63\u5e38\u5316\u3059\u308b\u6839\u672c\u7684\u306a\u6cbb\u7642\u6cd5\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u6cbb\u7642\u306f\u3001\u75c7\u72b6\u3092\u7ba1\u7406\u3057\u751f\u6d3b\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b**\u300c\u591a\u8077\u7a2e\u9023\u643a\u306b\u3088\u308b\u5bfe\u75c7\u7642\u6cd5\u300d**\u304c\u4e2d\u5fc3\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>1. \u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\uff08\u65e9\u671f\u4ecb\u5165\uff09<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7406\u5b66\u7642\u6cd5\uff08PT\uff09:<\/strong> \u4e73\u5150\u671f\u306e\u4f4e\u7dca\u5f35\u306b\u5bfe\u3059\u308b\u7b4b\u8089\u3078\u306e\u523a\u6fc0\u3084\u3001\u6b63\u3057\u3044\u59ff\u52e2\u306e\u4fdd\u6301\u3001\u904b\u52d5\u767a\u9054\u306e\u4fc3\u9032\u3002<\/li>\n\n\n\n<li><strong>\u4f5c\u696d\u7642\u6cd5\uff08OT\uff09:<\/strong> \u624b\u5148\u306e\u6a5f\u80fd\u8a13\u7df4\u3084\u3001\u65e5\u5e38\u751f\u6d3b\u52d5\u4f5c\uff08\u98df\u4e8b\u3001\u66f4\u8863\u306a\u3069\uff09\u306e\u8a13\u7df4\u3002\u6307\u306e\u7570\u5e38\u304c\u3042\u308b\u5834\u5408\u306e\u5de5\u592b\u3092\u652f\u63f4\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u8a00\u8a9e\u7642\u6cd5\uff08ST\uff09:<\/strong> \u6442\u98df\u56a5\u4e0b\u8a13\u7df4\u304a\u3088\u3073\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u652f\u63f4\u3002\u8868\u51fa\u8a00\u8a9e\u306e\u9045\u308c\u304c\u5f37\u3044\u305f\u3081\u3001\u30b5\u30a4\u30f3\u8a00\u8a9e\u3084\u7d75\u30ab\u30fc\u30c9\u3001\u30bf\u30d6\u30ec\u30c3\u30c8\u7aef\u672b\u3092\u6d3b\u7528\u3057\u305f\u4ee3\u66ff\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u306e\u5c0e\u5165\u3092\u65e9\u671f\u304b\u3089\u691c\u8a0e\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>2. \u5185\u79d1\u7684\u30fb\u5916\u79d1\u7684\u6cbb\u7642<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6574\u5f62\u5916\u79d1\u7684\u30d5\u30a9\u30ed\u30fc:<\/strong> \u810a\u67f1\u5074\u5f2f\u75c7\u3084\u8db3\u306e\u5909\u5f62\u306b\u5bfe\u3059\u308b\u5b9a\u671f\u7684\u306a\u30c1\u30a7\u30c3\u30af\u3068\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u305f\u88c5\u5177\u7642\u6cd5\u3084\u624b\u8853\u3002<\/li>\n\n\n\n<li><strong>\u5185\u5206\u6ccc\u79d1\u7684\u30d5\u30a9\u30ed\u30fc:<\/strong> \u8457\u3057\u3044\u4f4e\u8eab\u9577\u304c\u3042\u308b\u5834\u5408\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u6210\u9577\u306e\u7ba1\u7406\u3092\u884c\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u773c\u79d1\u7684\u30d5\u30a9\u30ed\u30fc:<\/strong> \u659c\u8996\u3084\u8996\u529b\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u77ef\u6b63\u3002<\/li>\n\n\n\n<li><strong>\u6ccc\u5c3f\u5668\u79d1\u624b\u8853:<\/strong> \u7537\u5150\u306e\u505c\u7559\u7cbe\u5de3\u306b\u5bfe\u3059\u308b\u56fa\u5b9a\u8853\u306a\u3069\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>3. \u6559\u80b2\u30fb\u793e\u4f1a\u7684\u652f\u63f4<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u77e5\u7684\u767a\u9054\u6bb5\u968e\u306b\u5408\u308f\u305b\u305f\u7279\u5225\u652f\u63f4\u6559\u80b2\u3002<\/li>\n\n\n\n<li>\u5bb6\u65cf\u306b\u5bfe\u3059\u308b\u5fc3\u7406\u7684\u30b1\u30a2\u3001\u304a\u3088\u3073\u5730\u57df\u306e\u798f\u7949\u30b5\u30fc\u30d3\u30b9\uff08\u7642\u80b2\u624b\u5e33\u306e\u53d6\u5f97\u3001\u30ec\u30b9\u30d1\u30a4\u30c8\u30b1\u30a2\u306a\u3069\uff09\u306e\u6d3b\u7528\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u4e88\u5f8c<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u751f\u5b58\u671f\u9593:<\/strong> \u5fc3\u75be\u60a3\u306a\u3069\u306e\u91cd\u8981\u81d3\u5668\u306e\u5408\u4f75\u75c7\u304c\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u305f\u3081\u3001\u591a\u304f\u306e\u65b9\u304c\u6210\u4eba\u671f\u3092\u8fce\u3048\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u751f\u6d3b\u306e\u8cea:<\/strong> \u91cd\u5ea6\u306e\u77e5\u7684\u969c\u5bb3\u3092\u4f34\u3046\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u304c\u3001\u793e\u4ea4\u7684\u306a\u6027\u683c\u3092\u6301\u3064\u3053\u3068\u3082\u3042\u308a\u3001\u9069\u5207\u306a\u793e\u4f1a\u7684\u30b5\u30dd\u30fc\u30c8\u3092\u53d7\u3051\u306a\u304c\u3089\u7a4f\u3084\u304b\u306a\u751f\u6d3b\u3092\u9001\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u751f\u6daf\u306b\u308f\u305f\u308a\u4e00\u5b9a\u306e\u4ecb\u52a9\u304c\u5fc5\u8981\u3068\u306a\u308b\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>Trisomy 9p syndrome\uff089p\u30c8\u30ea\u30bd\u30df\u30fc\u75c7\u5019\u7fa4\uff09\u306f\u30019\u756a\u67d3\u8272\u4f53\u306e\u4e00\u90e8\u304c\u901a\u5e38\u3088\u308a1\u3064\u5206\u591a\u304f\u5b58\u5728\u3059\u308b\u3053\u3068\u3067\u8d77\u3053\u308b\u3001\u67d3\u8272\u4f53\u7570\u5e38\u75c7\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4e3b\u306a\u7279\u5fb4\u3068\u3057\u3066\u3001\u76ee\u304c\u5965\u307e\u3063\u3066\u3044\u308b\u3088\u3046\u306b\u898b\u3048\u308b\u72ec\u7279\u306e\u9854\u7acb\u3061\u3001\u8a00\u8449\u306e\u767a\u9054\u306e\u3086\u3063\u304f\u308a\u3055\u3001\u305d\u3057\u3066\u6307\u306e\u9aa8\u306e\u6210\u9577\u304c\u672a\u767a\u9054\u3067\u3042\u308b\u3053\u3068\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u75c5\u6c17\u306f\u3001\u6210\u9577\u3084\u795e\u7d4c\u306e\u767a\u9054\u306b\u5927\u5207\u306a\u8a2d\u8a08\u56f3\uff08\u907a\u4f1d\u5b50\uff09\u304c\u904e\u5270\u306b\u50cd\u3044\u3066\u3057\u307e\u3046\u3053\u3068\u3067\u3001\u5168\u8eab\u306b\u3055\u307e\u3056\u307e\u306a\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u591a\u304f\u306e\u5834\u5408\u3001\u89aa\u5fa1\u3055\u3093\u306e\u67d3\u8272\u4f53\u306e\u69cb\u9020\u5909\u5316\uff08\u8ee2\u5ea7\uff09\u304c\u304d\u3063\u304b\u3051\u3068\u306a\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u306f\u6c7a\u3057\u3066\u8ab0\u306e\u305b\u3044\u3067\u3082\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u6839\u672c\u7684\u306a\u6cbb\u7642\u6cd5\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u65e9\u304f\u304b\u3089\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u3092\u59cb\u3081\u3001\u533b\u7642\u30c1\u30fc\u30e0\u3068\u5bc6\u306b\u9023\u643a\u3059\u308b\u3053\u3068\u3067\u3001\u304a\u5b50\u69d8\u306e\u6301\u3064\u53ef\u80fd\u6027\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3057\u3001\u5065\u3084\u304b\u306a\u751f\u6d3b\u3092\u652f\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u5c02\u9580\u533b\u3084\u7642\u80b2\u30c1\u30fc\u30e0\u3068\u5171\u306b\u3001\u304a\u5b50\u69d8\u306e\u6b69\u5e45\u306b\u5408\u308f\u305b\u305f\u6210\u9577\u3092\u9577\u304f\u6e29\u304b\u304f\u652f\u3048\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u53c2\u8003\u6587\u732e\u5143<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Rethor\u00e9, M. O., et al.<\/strong> (1970). <em>Sur quatre cas de trisomie pour le bras court du chromosome 9. Individualisation d&#8217;une nouvelle entit\u00e9 morbide.<\/em> Ann Genet.\n<ul class=\"wp-block-list\">\n<li>\uff08\u535a\u58eb\u3089\u306b\u3088\u308b\u6700\u521d\u306e\u75c7\u4f8b\u5831\u544a\u30029p\u30c8\u30ea\u30bd\u30df\u30fc\u3092\u72ec\u7acb\u3057\u305f\u75be\u60a3\u3068\u3057\u3066\u78ba\u7acb\u3057\u305f\u8ad6\u6587\u3002\uff09<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Schinzel, A.<\/strong> (2001). <em>Catalogue of Unbalanced Chromosome Aberrations in Man.<\/em> Walter de Gruyter.\n<ul class=\"wp-block-list\">\n<li>\uff08\u67d3\u8272\u4f53\u7570\u5e38\u306e\u4e16\u754c\u7684\u6a29\u5a01\u306b\u3088\u308b\u30019p\u30c8\u30ea\u30bd\u30df\u30fc\u306e\u81e8\u5e8a\u7684\u7279\u5fb4\u3092\u7db2\u7f85\u3057\u305f\u6587\u732e\u3002\uff09<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>GeneReviews\u00ae [Internet]<\/strong>: <em>Trisomy 9p (Partial)<\/em>. (NCBI).\n<ul class=\"wp-block-list\">\n<li>\uff08\u6700\u65b0\u306e\u533b\u5b66\u7684\u77e5\u898b\u3001\u8a3a\u65ad\u3001\u7ba1\u7406\u6307\u91dd\u304c\u7db2\u7f85\u3055\u308c\u3066\u3044\u308b\u4e16\u754c\u7684\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3002\uff09<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Orphanet<\/strong>: <em>Trisomy 9p (ORPHA:96146)<\/em>.\n<ul class=\"wp-block-list\">\n<li>\uff08\u5e0c\u5c11\u75be\u60a3\u306e\u56fd\u969b\u7684\u306a\u30dd\u30fc\u30bf\u30eb\u30b5\u30a4\u30c8\u306b\u3088\u308b\u75c5\u614b\u6982\u8981\u3068\u30ea\u30bd\u30fc\u30b9\u60c5\u5831\u3002\uff09<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Unique (The Rare Chromosome Disorder Support Group)<\/strong>: <em>9p duplications: A guide for families<\/em>.\n<ul class=\"wp-block-list\">\n<li>\uff08\u5e0c\u5c11\u67d3\u8272\u4f53\u7570\u5e38\u652f\u63f4\u56e3\u4f53\u306b\u3088\u308b\u3001\u3054\u5bb6\u65cf\u5411\u3051\u306e\u308f\u304b\u308a\u3084\u3059\u3044\u30ac\u30a4\u30c9\u8cc7\u6599\u3002\uff09<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Guilherme, R. S., et al.<\/strong> (2012). <em>Clinical and molecular characterization of nine patients with 9p duplications: Evidence for a critical region in 9p22.1-p22.3.<\/em>\n<ul class=\"wp-block-list\">\n<li>\uff08\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u89e3\u6790\u3092\u7528\u3044\u3066\u3001\u75c7\u72b6\u306e\u4e3b\u56e0\u3068\u306a\u308b\u8cac\u4efb\u9818\u57df\u3092\u5206\u6790\u3057\u305f\u7814\u7a76\u3002\uff09<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Zou, Y. S., et al.<\/strong> (2015). <em>Microduplication of 9p24.3p24.2: Report of a case and review of the literature.<\/em>\n<ul class=\"wp-block-list\">\n<li>\uff089p\u672b\u7aef\u306e<strong>\u5fae\u5c0f<\/strong>\u91cd\u8907\u3068\u81e8\u5e8a\u75c7\u72b6\u306e\u76f8\u95a2\u306b\u95a2\u3059\u308b\u6700\u65b0\u306e\u77e5\u898b\u3002\uff09<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<style>\n.entry-content li {\n  text-indent: -1rem !important;\n}\n<\/style>\n<p>\u8a73\u3057\u304f\u306f <a href=\"https:\/\/www.hiro-clinic.or.jp\/gene\/clinic\/\">\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af\u5168\u56fd\u306e\u30af\u30ea\u30cb\u30c3\u30af\u4e00\u89a7<\/a> \u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>","protected":false},"featured_media":0,"template":"","class_list":["post-17507","genetic-screening","type-genetic-screening","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/genetic-screening\/17507","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/genetic-screening"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/types\/genetic-screening"}],"version-history":[{"count":2,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/genetic-screening\/17507\/revisions"}],"predecessor-version":[{"id":17509,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/genetic-screening\/17507\/revisions\/17509"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media?parent=17507"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}