{"id":10055,"date":"2025-03-14T08:51:16","date_gmt":"2025-03-14T08:51:16","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=10055"},"modified":"2025-03-14T08:51:18","modified_gmt":"2025-03-14T08:51:18","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e9%81%8b%e5%8b%95%e4%b8%8d%e8%b6%b3%e3%81%ae%e5%bd%b1%e9%9f%bf%ef%bc%9a%e5%81%a5%e5%ba%b7%e7%ae%a1%e7%90%86%e3%81%ae%e8%a6%96%e7%82%b9","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e9%81%8b%e5%8b%95%e4%b8%8d%e8%b6%b3%e3%81%ae%e5%bd%b1%e9%9f%bf%ef%bc%9a%e5%81%a5%e5%ba%b7%e7%ae%a1%e7%90%86%e3%81%ae%e8%a6%96%e7%82%b9\/","title":{"rendered":"\u907a\u4f1d\u5b50\u3068\u904b\u52d5\u4e0d\u8db3\u306e\u5f71\u97ff\uff1a\u5065\u5eb7\u7ba1\u7406\u306e\u8996\u70b9"},"content":{"rendered":"\n<p>\u73fe\u4ee3\u793e\u4f1a\u306b\u304a\u3044\u3066\u3001\u904b\u52d5\u4e0d\u8db3\u306f\u6df1\u523b\u306a\u5065\u5eb7\u554f\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u5f71\u97ff\u306f\u5358\u306b\u80a5\u6e80\u3084\u751f\u6d3b\u7fd2\u6163\u75c5\u306b\u3068\u3069\u307e\u3089\u305a\u3001\u907a\u4f1d\u5b50\u30ec\u30d9\u30eb\u3067\u306e\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3084\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3001\u3055\u3089\u306b\u306f\u500b\u5225\u306e\u907a\u4f1d\u7684\u7279\u6027\u306b\u57fa\u3065\u3044\u305f\u5065\u5eb7\u7ba1\u7406\u306e\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u3001\u79d1\u5b66\u7684\u306a\u8996\u70b9\u304b\u3089\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u3068\u904b\u52d5\u4e0d\u8db3\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u306f\u3001\u7b4b\u8089\u3084\u5fc3\u80ba\u6a5f\u80fd\u306e\u5f37\u5316\u3060\u3051\u3067\u306a\u304f\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u91cd\u8981\u306a\u8981\u7d20\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u904b\u52d5\u306b\u3088\u3063\u3066<strong>PGC-1\u03b1<\/strong>\u3084<strong>AMPK<\/strong>\u306a\u3069\u306e\u907a\u4f1d\u5b50\u304c\u6d3b\u6027\u5316\u3055\u308c\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3084\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u304c\u5411\u4e0a\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u4f4e\u4e0b\u3057\u3001\u4ee3\u8b1d\u306e\u4f4e\u4e0b\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u5897\u52a0\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u5ea7\u308a\u304c\u3061\u306a\u751f\u6d3b\u7fd2\u6163\u306f<strong>SIRT1<\/strong>\uff08\u30b5\u30fc\u30c1\u30e5\u30a4\u30f3\u907a\u4f1d\u5b50\uff09\u306a\u3069\u306e\u9577\u5bff\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u8001\u5316\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u904b\u52d5\u7fd2\u6163<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u306f\uff1f<\/strong><\/h3>\n\n\n\n<p>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u306f\u3001DNA\u914d\u5217\u305d\u306e\u3082\u306e\u3092\u5909\u3048\u305a\u306b\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u4ed5\u7d44\u307f\u3067\u3059\u3002\u98df\u4e8b\u3001\u30b9\u30c8\u30ec\u30b9\u3001\u904b\u52d5\u306a\u3069\u306e\u74b0\u5883\u8981\u56e0\u306b\u3088\u3063\u3066\u3001<strong>DNA\u30e1\u30c1\u30eb\u5316<\/strong>\u3084<strong>\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe<\/strong>\u304c\u5909\u5316\u3057\u3001\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u304c\u9577\u671f\u9593\u306b\u308f\u305f\u3063\u3066\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u904b\u52d5\u306b\u3088\u308b\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u5909\u5316<\/strong><\/h3>\n\n\n\n<p>\u904b\u52d5\u306f\u30dd\u30b8\u30c6\u30a3\u30d6\u306a\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u5b9a\u671f\u7684\u306a\u904b\u52d5\u306f**BDNF\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09**\u306e\u767a\u73fe\u3092\u4fc3\u9032\u3057\u3001\u8133\u306e\u53ef\u5851\u6027\u3084\u8a8d\u77e5\u6a5f\u80fd\u3092\u5411\u4e0a\u3055\u305b\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u904b\u52d5\u4e0d\u8db3\u306f\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u6291\u5236\u3057\u3001\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306e\u5897\u52a0\u3068\u95a2\u9023\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068<strong>PPARGC1A<\/strong>\u907a\u4f1d\u5b50\u306e\u30e1\u30c1\u30eb\u5316\u304c\u9032\u307f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3084\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u907a\u4f1d\u5b50\u591a\u578b\u3068\u904b\u52d5\u80fd\u529b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"574\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-1024x574.jpg\" alt=\"\u79cb\u306e\u5c71\u3068\u65e5\u672c\u4eba\u306e\u7537\u306e\u5b50\" class=\"wp-image-9821\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-1024x574.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-300x168.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-768x430.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-1536x861.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u904b\u52d5\u80fd\u529b\u306b\u306f\u3001\u500b\u4eba\u306e\u907a\u4f1d\u7684\u80cc\u666f\u304c\u5927\u304d\u304f\u5f71\u97ff\u3057\u307e\u3059\u3002\u7279\u306b<strong>ACTN3<\/strong>\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306f\u3001\u7b4b\u7e4a\u7dad\u306e\u30bf\u30a4\u30d7\u306b\u95a2\u4fc2\u3057\u3001\u77ac\u767a\u529b\u3084\u6301\u4e45\u529b\u306b\u9055\u3044\u3092\u751f\u3058\u3055\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u907a\u4f1d\u5b50<\/th><th>\u30bf\u30a4\u30d7<\/th><th>\u7279\u5fb4<\/th><\/tr><\/thead><tbody><tr><td><strong>ACTN3 RR\u578b<\/strong><\/td><td>\u901f\u7b4b\u512a\u4f4d<\/td><td>\u77ed\u8ddd\u96e2\u8d70\u3084\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5411\u304d<\/td><\/tr><tr><td><strong>ACTN3 RX\u578b<\/strong><\/td><td>\u4e2d\u9593\u578b<\/td><td>\u30d0\u30e9\u30f3\u30b9\u306e\u53d6\u308c\u305f\u904b\u52d5\u80fd\u529b<\/td><\/tr><tr><td><strong>ACTN3 XX\u578b<\/strong><\/td><td>\u9045\u7b4b\u512a\u4f4d<\/td><td>\u9577\u8ddd\u96e2\u8d70\u3084\u6301\u4e45\u7cfb\u30b9\u30dd\u30fc\u30c4\u5411\u304d<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u7684\u306a\u80cc\u666f\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u81ea\u5206\u306b\u9069\u3057\u305f\u904b\u52d5\u65b9\u6cd5\u3092\u9078\u3076\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u904b\u52d5\u4e0d\u8db3\u306b\u3088\u308b\u75be\u60a3\u30ea\u30b9\u30af\u3068\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u4e0d\u8db3\u306f\u3001\u3055\u307e\u3056\u307e\u306a\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u307e\u3059\u304c\u3001\u305d\u306e\u5f71\u97ff\u306f\u907a\u4f1d\u7684\u8981\u56e0\u3068\u3082\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u80a5\u6e80\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>FTO\u907a\u4f1d\u5b50<\/strong>\u306f\u80a5\u6e80\u3068\u95a2\u9023\u304c\u6df1\u304f\u3001\u7279\u5b9a\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u904b\u52d5\u4e0d\u8db3\u306e\u5f71\u97ff\u3092\u3088\u308a\u5f37\u304f\u53d7\u3051\u3084\u3059\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u9069\u5ea6\u306a\u904b\u52d5\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u3053\u306e\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7cd6\u5c3f\u75c5\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>TCF7L2\u907a\u4f1d\u5b50<\/strong>\u306f\u7cd6\u5c3f\u75c5\u306e\u767a\u75c7\u30ea\u30b9\u30af\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u9ad8\u307e\u308a\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u904b\u52d5\u3092\u7fd2\u6163\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u6291\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u5fc3\u8840\u7ba1\u75be\u60a3\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>NOS3\u907a\u4f1d\u5b50<\/strong>\u306f\u8840\u7ba1\u306e\u5065\u5eb7\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u904b\u52d5\u306b\u3088\u3063\u3066\u4e00\u9178\u5316\u7a92\u7d20\uff08NO\uff09\u306e\u7523\u751f\u3092\u4fc3\u9032\u3057\u3001\u8840\u6d41\u3092\u6539\u5584\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u3053\u306e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3001\u9ad8\u8840\u5727\u3084\u52d5\u8108\u786c\u5316\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u500b\u5225\u5316\u533b\u7642\u3068\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d3b\u7528<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u6280\u8853\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u500b\u4eba\u306e\u907a\u4f1d\u7684\u7279\u5fb4\u306b\u57fa\u3065\u3044\u305f\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u81ea\u5206\u306b\u9069\u3057\u305f\u904b\u52d5\u306e\u7a2e\u985e\u3084\u751f\u6d3b\u7fd2\u6163\u306e\u8abf\u6574\u65b9\u6cd5\u3092\u77e5\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u5e02\u8ca9\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>23andMe<\/strong>\uff08\u904b\u52d5\u80fd\u529b\u3084\u80a5\u6e80\u30ea\u30b9\u30af\u89e3\u6790\uff09<\/li>\n\n\n\n<li><strong>MyHeritage DNA<\/strong>\uff08\u5065\u5eb7\u30ea\u30b9\u30af\u8a55\u4fa1\uff09<\/li>\n\n\n\n<li><strong>GeneLife<\/strong>\uff08\u65e5\u672c\u4eba\u5411\u3051\u306e\u907a\u4f1d\u5b50\u5206\u6790\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u6700\u65b0\u306e\u7814\u7a76\u3068\u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31033284_m-1024x683.jpg\" alt=\"PC\u3067\u4f5c\u696d\u3059\u308b\u533b\u7642\u5f93\u4e8b\u8005\" class=\"wp-image-9562\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31033284_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31033284_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31033284_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31033284_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31033284_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u6700\u65b0\u306e\u7814\u7a76\u306b\u3088\u308b\u3068\u3001AI\u6280\u8853\u3092\u6d3b\u7528\u3057\u305f\u907a\u4f1d\u5b50\u89e3\u6790\u304c\u9032\u3093\u3067\u304a\u308a\u3001\u904b\u52d5\u7fd2\u6163\u3068\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u95a2\u4fc2\u3092\u3088\u308a\u8a73\u7d30\u306b\u5206\u6790\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001<strong>CRISPR-Cas9<\/strong>\u306a\u3069\u306e\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u3092\u7528\u3044\u305f\u7b4b\u529b\u5f37\u5316\u3084\u4ee3\u8b1d\u6539\u5584\u306e\u8a66\u307f\u3082\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u907a\u4f1d\u7684\u306b\u904b\u52d5\u80fd\u529b\u304c\u4f4e\u3044\u4eba\u3067\u3082\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3092\u8abf\u6574\u3059\u308b\u3053\u3068\u3067\u5065\u5eb7\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4ee5\u4e0b\u306e\u7814\u7a76\u304c\u7279\u306b\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41576-021-00380-5\">Genetic and Epigenetic Influence on Physical Activity and Health<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3943438\/\">The Role of ACTN3 in Human Athletic Performance<\/a><\/li>\n\n\n\n<li><a>Exercise-Induced Epigenetic Modifications in Skeletal Muscle<\/a><\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>7. \u904b\u52d5\u4e0d\u8db3\u304c\u795e\u7d4c\u7cfb\u306b\u4e0e\u3048\u308b\u907a\u4f1d\u7684\u5f71\u97ff<\/strong><\/p>\n\n\n\n<p>\u904b\u52d5\u306f\u7b4b\u8089\u3084\u5fc3\u80ba\u6a5f\u80fd\u3060\u3051\u3067\u306a\u304f\u3001\u8133\u306e\u5065\u5eb7\u306b\u3082\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u795e\u7d4c\u7cfb\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u304c\u5909\u5316\u3057\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3084\u7cbe\u795e\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>BDNF\u907a\u4f1d\u5b50\u3068\u8133\u306e\u53ef\u5851\u6027<\/strong><\/h3>\n\n\n\n<p>**BDNF\uff08Brain-Derived Neurotrophic Factor\uff09**\u907a\u4f1d\u5b50\u306f\u3001\u8133\u306e\u53ef\u5851\u6027\u3084\u795e\u7d4c\u7d30\u80de\u306e\u6210\u9577\u3092\u4fc3\u9032\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u904b\u52d5\u306b\u3088\u3063\u3066\u3053\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u5897\u52a0\u3057\u3001\u8a18\u61b6\u529b\u306e\u5411\u4e0a\u3084\u795e\u7d4c\u5909\u6027\u75be\u60a3\u306e\u4e88\u9632\u306b\u5f79\u7acb\u3064\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068BDNF\u306e\u767a\u73fe\u304c\u4f4e\u4e0b\u3057\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5f71\u97ff\u304c\u73fe\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u8a18\u61b6\u529b\u306e\u4f4e\u4e0b<\/li>\n\n\n\n<li>\u3046\u3064\u75c5\u3084\u4e0d\u5b89\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u5897\u52a0<\/li>\n\n\n\n<li>\u8a8d\u77e5\u75c7\u306e\u767a\u75c7\u30ea\u30b9\u30af\u4e0a\u6607<\/li>\n<\/ul>\n\n\n\n<p>BDNF\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306f\u3001\u7279\u306b<strong>\u6709\u9178\u7d20\u904b\u52d5<\/strong>\u306b\u3088\u3063\u3066\u6d3b\u6027\u5316\u3055\u308c\u3084\u3059\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30c9\u30fc\u30d1\u30df\u30f3\u95a2\u9023\u907a\u4f1d\u5b50\u3068\u904b\u52d5\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p><strong>DRD2\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u904b\u52d5\u306b\u3088\u3063\u3066\u3053\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u5909\u5316\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u30c9\u30fc\u30d1\u30df\u30f3\u306f\u904b\u52d5\u306e\u7d99\u7d9a\u306b\u95a2\u308f\u308b\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u3084\u5831\u916c\u7cfb\u3092\u5236\u5fa1\u3059\u308b\u305f\u3081\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u3084\u308b\u6c17\u306e\u4f4e\u4e0b\u3084\u7121\u6c17\u529b\u611f\u304c\u751f\u3058\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u7b4b\u8089\u306e\u907a\u4f1d\u5b50\u3068\u904b\u52d5\u4e0d\u8db3\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-1024x683.jpg\" alt=\"\u75b2\u52b4\u30fb\u606f\u5207\u308c\u30fb\u30af\u30fc\u30eb\u30c0\u30a6\u30f3\u306e\u82e5\u3044\u7537\u6027\" class=\"wp-image-9592\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u7b4b\u8089\u306e\u840e\u7e2e\u3084\u6a5f\u80fd\u4f4e\u4e0b\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u7b4b\u8089\u7279\u7570\u7684\u306a\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u5909\u5316\u3059\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>FOXO3\u907a\u4f1d\u5b50\u3068\u7b4b\u840e\u7e2e<\/strong><\/h3>\n\n\n\n<p><strong>FOXO3\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u8001\u5316\u3084\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u306b\u95a2\u4e0e\u3057\u3001\u7b4b\u8089\u306e\u5206\u89e3\u3092\u5236\u5fa1\u3059\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u5897\u52a0\u3057\u3001\u7b4b\u840e\u7e2e\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u9006\u306b\u3001\u9069\u5ea6\u306a\u904b\u52d5\u3092\u884c\u3046\u3053\u3068\u3067FOXO3\u306e\u767a\u73fe\u304c\u6291\u5236\u3055\u308c\u3001\u7b4b\u8089\u91cf\u306e\u7dad\u6301\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u7279\u306b**\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08\u7b4b\u30c8\u30ec\uff09**\u304c\u6709\u52b9\u3067\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u3068\u904b\u52d5\u4e0d\u8db3<\/strong><\/h3>\n\n\n\n<p>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u7d30\u80de\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u7523\u751f\u3092\u62c5\u3063\u3066\u304a\u308a\u3001\u904b\u52d5\u306b\u3088\u3063\u3066\u305d\u306e\u6a5f\u80fd\u304c\u6d3b\u6027\u5316\u3055\u308c\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001<strong>PPARGC1A\u907a\u4f1d\u5b50<\/strong>\u306e\u767a\u73fe\u304c\u4f4e\u4e0b\u3057\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6a5f\u80fd\u4f4e\u4e0b\u304c\u8d77\u3053\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5f71\u97ff\u304c\u751f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u75b2\u308c\u3084\u3059\u304f\u306a\u308b<\/li>\n\n\n\n<li>\u4ee3\u8b1d\u306e\u4f4e\u4e0b<\/li>\n\n\n\n<li>\u7b4b\u6301\u4e45\u529b\u306e\u4f4e\u4e0b<\/li>\n<\/ul>\n\n\n\n<p>PPARGC1A\u907a\u4f1d\u5b50\u306f\u3001\u6709\u9178\u7d20\u904b\u52d5\u306b\u3088\u3063\u3066\u6d3b\u6027\u5316\u3055\u308c\u3084\u3059\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u904b\u52d5\u4e0d\u8db3\u306e\u89e3\u6d88\u306b\u306f\u30b8\u30e7\u30ae\u30f3\u30b0\u3084\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u304c\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u907a\u4f1d\u7684\u8981\u56e0\u306b\u57fa\u3065\u304f\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u6700\u9069\u5316<\/strong><\/h2>\n\n\n\n<p>\u500b\u4eba\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u8003\u616e\u3057\u305f\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u4f5c\u6210\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u904b\u52d5\u306e\u7a2e\u985e\u3068\u907a\u4f1d\u7684\u9069\u6027<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50<\/strong><\/td><td><strong>\u907a\u4f1d\u7684\u7279\u6027<\/strong><\/td><td><strong>\u9069\u3057\u305f\u904b\u52d5<\/strong><\/td><\/tr><tr><td><strong>ACTN3<\/strong><\/td><td>\u901f\u7b4b\u512a\u4f4d\uff08RR\u578b\uff09<\/td><td>\u77ed\u8ddd\u96e2\u8d70\u3001\u7b4b\u30c8\u30ec<\/td><\/tr><tr><td><strong>ACE<\/strong><\/td><td>\u6301\u4e45\u529b\u5411\u4e0a\uff08I\u578b\uff09<\/td><td>\u9577\u8ddd\u96e2\u8d70\u3001\u30b5\u30a4\u30af\u30ea\u30f3\u30b0<\/td><\/tr><tr><td><strong>PPARGC1A<\/strong><\/td><td>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u5411\u4e0a<\/td><td>\u6709\u9178\u7d20\u904b\u52d5\u3001HIIT<\/td><\/tr><tr><td><strong>FOXO3<\/strong><\/td><td>\u7b4b\u840e\u7e2e\u30ea\u30b9\u30af\u9ad8<\/td><td>\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u500b\u5225\u5316\u3055\u308c\u305f\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u8a2d\u8a08\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u904b\u52d5\u4e0d\u8db3\u304c\u514d\u75ab\u7cfb\u306b\u4e0e\u3048\u308b\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-1024x683.jpg\" alt=\"\" class=\"wp-image-9900\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u904b\u52d5\u306f\u514d\u75ab\u7cfb\u306e\u8abf\u7bc0\u306b\u3082\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u514d\u75ab\u7cfb\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u3001\u611f\u67d3\u75c7\u3084\u6162\u6027\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>IL6\u907a\u4f1d\u5b50\u3068\u708e\u75c7\u53cd\u5fdc<\/strong><\/h3>\n\n\n\n<p><strong>IL6\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3067\u3042\u308b\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f36\uff08IL-6\uff09\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u9069\u5ea6\u306a\u904b\u52d5\u306fIL-6\u306e\u9069\u5207\u306a\u5206\u6ccc\u3092\u4fc3\u3057\u3001\u514d\u75ab\u6a5f\u80fd\u3092\u5411\u4e0a\u3055\u305b\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068IL-6\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u3001\u6162\u6027\u708e\u75c7\u304c\u4fc3\u9032\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6162\u6027\u708e\u75c7\u306f\u4ee5\u4e0b\u306e\u75be\u60a3\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u52d5\u8108\u786c\u5316<\/strong><\/li>\n\n\n\n<li><strong>\u7cd6\u5c3f\u75c5<\/strong><\/li>\n\n\n\n<li><strong>\u81ea\u5df1\u514d\u75ab\u75be\u60a3<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u904b\u52d5\u3092\u7fd2\u6163\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u708e\u75c7\u3092\u6291\u3048\u3001\u514d\u75ab\u6a5f\u80fd\u3092\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. \u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3057\u305f\u5065\u5eb7\u7ba1\u7406\u306e\u672a\u6765<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u6280\u8853\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u500b\u4eba\u306e\u907a\u4f1d\u60c5\u5831\u306b\u57fa\u3065\u3044\u305f\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d3b\u7528\u4f8b<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u691c\u67fb\u9805\u76ee<\/strong><\/td><td><strong>\u95a2\u9023\u907a\u4f1d\u5b50<\/strong><\/td><td><strong>\u5065\u5eb7\u7ba1\u7406\u3078\u306e\u5fdc\u7528<\/strong><\/td><\/tr><tr><td><strong>\u904b\u52d5\u9069\u6027<\/strong><\/td><td>ACTN3, ACE<\/td><td>\u500b\u5225\u306e\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u4f5c\u6210<\/td><\/tr><tr><td><strong>\u4ee3\u8b1d\u6a5f\u80fd<\/strong><\/td><td>PPARGC1A, FTO<\/td><td>\u98df\u4e8b\u30fb\u904b\u52d5\u306e\u6700\u9069\u5316<\/td><\/tr><tr><td><strong>\u514d\u75ab\u6a5f\u80fd<\/strong><\/td><td>IL6, TNF-\u03b1<\/td><td>\u708e\u75c7\u30ea\u30b9\u30af\u306e\u7ba1\u7406<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u904b\u52d5\u30fb\u98df\u4e8b\u30fb\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u9078\u629e\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>12. \u6700\u65b0\u306e\u7814\u7a76\u3068\u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u4e0d\u8db3\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u7814\u7a76\u304c\u9032\u3093\u3067\u304a\u308a\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5206\u91ce\u3067\u65b0\u305f\u306a\u767a\u898b\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u904b\u52d5\u306e\u95a2\u4fc2\u306e\u8a73\u7d30\u306a\u89e3\u6790<\/strong><\/li>\n\n\n\n<li><strong>AI\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u958b\u767a<\/strong><\/li>\n\n\n\n<li><strong>\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306b\u3088\u308b\u7b4b\u529b\u4f4e\u4e0b\u306e\u4e88\u9632<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u4ee5\u4e0b\u306e\u7814\u7a76\u304c\u7279\u306b\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41576-021-00380-5\">Epigenetic Modifications and Exercise: A Review<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3943438\/\">Role of IL-6 in Exercise and Inflammation<\/a><\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>13. \u904b\u52d5\u4e0d\u8db3\u304c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u306b\u4e0e\u3048\u308b\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/29217899_m-1024x683.jpg\" alt=\"\" class=\"wp-image-9254\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29217899_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29217899_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29217899_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29217899_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29217899_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u7d30\u80de\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u7523\u751f\u3092\u62c5\u3046\u91cd\u8981\u306a\u7d30\u80de\u5c0f\u5668\u5b98\u3067\u3059\u304c\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\uff08mtDNA\uff09\u306b\u5909\u5316\u304c\u751f\u3058\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306b\u60aa\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d<\/strong><\/h3>\n\n\n\n<p>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u72ec\u81ea\u306eDNA\u3092\u6301\u3061\u3001ATP\uff08\u30a2\u30c7\u30ce\u30b7\u30f3\u4e09\u30ea\u30f3\u9178\uff09\u306e\u7523\u751f\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5909\u5316\u304c\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>mtDNA\u306e\u30b3\u30d4\u30fc\u6570\u6e1b\u5c11<\/strong> \u2192 \u7d30\u80de\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u7523\u751f\u80fd\u529b\u304c\u4f4e\u4e0b<\/li>\n\n\n\n<li><strong>\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u5897\u52a0<\/strong> \u2192 DNA\u640d\u50b7\u3084\u7d30\u80de\u8001\u5316\u306e\u4fc3\u9032<\/li>\n\n\n\n<li><strong>\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u5897\u52a0<\/strong> \u2192 \u6162\u6027\u708e\u75c7\u306e\u30ea\u30b9\u30af\u4e0a\u6607<\/li>\n<\/ul>\n\n\n\n<p>\u904b\u52d5\u7fd2\u6163\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u3067\u3001mtDNA\u306e\u6a5f\u80fd\u304c\u7dad\u6301\u3055\u308c\u3001\u5065\u5eb7\u5bff\u547d\u306e\u5ef6\u9577\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u904b\u52d5\u306b\u3088\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u306e\u6539\u5584<\/strong><\/h3>\n\n\n\n<p>\u6709\u9178\u7d20\u904b\u52d5\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u65b0\u751f\uff08\u30d0\u30a4\u30aa\u30b8\u30a7\u30cd\u30b7\u30b9\uff09\u3092\u4fc3\u9032\u3057\u3001\u7d30\u80de\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u7523\u751f\u3092\u5411\u4e0a\u3055\u305b\u307e\u3059\u3002\u3053\u306e\u904e\u7a0b\u306b\u306f\u3001<strong>PPARGC1A\u907a\u4f1d\u5b50<\/strong>\u304c\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u9069\u5ea6\u306a\u904b\u52d5\u3092\u884c\u3046\u3053\u3068\u3067mtDNA\u306e\u7dad\u6301\u3084\u4fee\u5fa9\u304c\u4fc3\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>14. \u907a\u4f1d\u5b50\u3068\u904b\u52d5\u4e0d\u8db3\u306b\u3088\u308b\u8001\u5316\u306e\u52a0\u901f<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u4e0d\u8db3\u306f\u52a0\u9f62\u306b\u4f34\u3046\u907a\u4f1d\u5b50\u306e\u5909\u5316\u3092\u52a0\u901f\u3055\u305b\u3001\u8001\u5316\u3092\u65e9\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30c6\u30ed\u30e1\u30a2\u306e\u77ed\u7e2e\u3068\u8001\u5316<\/strong><\/h3>\n\n\n\n<p><strong>\u30c6\u30ed\u30e1\u30a2<\/strong>\u306f\u3001\u67d3\u8272\u4f53\u306e\u672b\u7aef\u3092\u4fdd\u8b77\u3059\u308b\u69cb\u9020\u3067\u3042\u308a\u3001\u7d30\u80de\u5206\u88c2\u306e\u305f\u3073\u306b\u77ed\u7e2e\u3057\u307e\u3059\u3002\u30c6\u30ed\u30e1\u30a2\u304c\u4e00\u5b9a\u306e\u9577\u3055\u4ee5\u4e0b\u306b\u306a\u308b\u3068\u3001\u7d30\u80de\u306e\u8001\u5316\u3084\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff08\u7d30\u80de\u6b7b\uff09\u304c\u5f15\u304d\u8d77\u3053\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u904b\u52d5\u4e0d\u8db3\u306e\u4eba\u306f\u30c6\u30ed\u30e1\u30a2\u306e\u77ed\u7e2e\u901f\u5ea6\u304c\u901f\u304f\u3001\u52a0\u9f62\u306b\u4f34\u3046\u75be\u60a3\uff08\u5fc3\u8840\u7ba1\u75be\u60a3\u3001\u7cd6\u5c3f\u75c5\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306a\u3069\uff09\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u904b\u52d5\u3092\u884c\u3046\u4eba<\/strong> \u2192 \u30c6\u30ed\u30e1\u30a2\u306e\u77ed\u7e2e\u901f\u5ea6\u304c\u9045\u304f\u3001\u7d30\u80de\u306e\u8001\u5316\u304c\u6291\u5236\u3055\u308c\u308b<\/li>\n\n\n\n<li><strong>\u904b\u52d5\u4e0d\u8db3\u306e\u4eba<\/strong> \u2192 \u30c6\u30ed\u30e1\u30a2\u306e\u77ed\u7e2e\u304c\u52a0\u901f\u3057\u3001\u65e9\u671f\u8001\u5316\u304c\u9032\u884c<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>SIRT1\u907a\u4f1d\u5b50\u3068\u9577\u5bff<\/strong><\/h3>\n\n\n\n<p>**SIRT1\uff08\u30b5\u30fc\u30c1\u30e5\u30a4\u30f31\uff09**\u907a\u4f1d\u5b50\u306f\u3001\u7d30\u80de\u306e\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u3084DNA\u4fee\u5fa9\u306b\u95a2\u4e0e\u3057\u3001\u9577\u5bff\u907a\u4f1d\u5b50\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u9069\u5ea6\u306a\u904b\u52d5\u3092\u884c\u3046\u3053\u3068\u3067\u3001SIRT1\u306e\u767a\u73fe\u304c\u5897\u52a0\u3057\u3001\u8001\u5316\u306e\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>15. \u904b\u52d5\u4e0d\u8db3\u3068\u8178\u5185\u7d30\u83cc\u53e2\u306e\u5909\u5316<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/2355241_m-1024x683.jpg\" alt=\"\" class=\"wp-image-8852\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/2355241_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/2355241_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/2355241_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/2355241_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/2355241_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8178\u5185\u7d30\u83cc\u53e2\uff08\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\uff09\u306f\u3001\u5065\u5eb7\u7dad\u6301\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u304c\u3001\u904b\u52d5\u4e0d\u8db3\u306b\u3088\u3063\u3066\u305d\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u904b\u52d5\u3068\u8178\u5185\u7d30\u83cc\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u9069\u5ea6\u306a\u904b\u52d5\u306f\u3001\u5584\u7389\u83cc\uff08Bifidobacterium\u3001Lactobacillus\u306a\u3069\uff09\u306e\u5897\u52a0\u3092\u4fc3\u3057\u3001\u8178\u5185\u74b0\u5883\u3092\u6574\u3048\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u60aa\u7389\u83cc\uff08Clostridium\u3001Proteobacteria\u306a\u3069\uff09\u304c\u5897\u52a0\u3057\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5f71\u97ff\u304c\u73fe\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8178\u5185\u306e\u708e\u75c7\u304c\u5897\u52a0<\/strong> \u2192 \u6162\u6027\u708e\u75c7\u306e\u30ea\u30b9\u30af\u4e0a\u6607<\/li>\n\n\n\n<li><strong>\u77ed\u9396\u8102\u80aa\u9178\uff08SCFA\uff09\u306e\u6e1b\u5c11<\/strong> \u2192 \u514d\u75ab\u6a5f\u80fd\u3084\u4ee3\u8b1d\u306e\u4f4e\u4e0b<\/li>\n\n\n\n<li><strong>\u8178\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u4f4e\u4e0b<\/strong> \u2192 \u6709\u5bb3\u7269\u8cea\u304c\u8840\u6db2\u4e2d\u306b\u6f0f\u308c\u51fa\u3057\u3001\u5168\u8eab\u306e\u708e\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u8178\u5185\u7d30\u83cc\u3068\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u6700\u65b0\u306e\u7814\u7a76\u3067\u306f\u3001\u8178\u5185\u7d30\u83cc\u304c\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3092\u4ecb\u3057\u3066\u907a\u4f1d\u5b50\u767a\u73fe\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u904b\u52d5\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u8178\u5185\u74b0\u5883\u304c\u6539\u5584\u3055\u308c\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u5909\u5316\u3092\u901a\u3058\u3066\u5065\u5eb7\u4fc3\u9032\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>16. \u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u3068\u904b\u52d5\u80fd\u529b\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u306e\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u904b\u52d5\u80fd\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u305f\u3081\u306e\u907a\u4f1d\u5b50\u6539\u5909\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>CRISPR-Cas9\u306b\u3088\u308b\u7b4b\u529b\u5f37\u5316\u306e\u53ef\u80fd\u6027<\/strong><\/h3>\n\n\n\n<p>CRISPR-Cas9\u3092\u7528\u3044\u305f\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306b\u3088\u308a\u3001\u7b4b\u8089\u306e\u6210\u9577\u3092\u5236\u5fa1\u3059\u308b\u907a\u4f1d\u5b50\u306e\u6539\u5909\u304c\u53ef\u80fd\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>MSTN\uff08\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\uff09\u907a\u4f1d\u5b50<\/strong>\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3001\u7b4b\u8089\u306e\u6210\u9577\u3092\u4fc3\u9032\u3057\u3001\u904b\u52d5\u80fd\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u8a66\u307f\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50<\/strong><\/td><td><strong>\u5f79\u5272<\/strong><\/td><td><strong>\u907a\u4f1d\u5b50\u7de8\u96c6\u306e\u5f71\u97ff<\/strong><\/td><\/tr><tr><td><strong>MSTN\uff08\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\uff09<\/strong><\/td><td>\u7b4b\u8089\u6210\u9577\u306e\u6291\u5236<\/td><td>\u6291\u5236\u3059\u308b\u3068\u7b4b\u8089\u304c\u5897\u52a0<\/td><\/tr><tr><td><strong>PPARGC1A<\/strong><\/td><td>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd<\/td><td>\u6d3b\u6027\u5316\u3059\u308b\u3068\u6301\u4e45\u529b\u5411\u4e0a<\/td><\/tr><tr><td><strong>FOXO3<\/strong><\/td><td>\u8001\u5316\u30fb\u7b4b\u840e\u7e2e<\/td><td>\u6291\u5236\u3059\u308b\u3068\u7b4b\u529b\u4f4e\u4e0b\u3092\u9632\u3050<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306a\u6280\u8853\u304c\u5b9f\u7528\u5316\u3055\u308c\u308c\u3070\u3001\u904b\u52d5\u4e0d\u8db3\u306b\u3088\u308b\u7b4b\u529b\u4f4e\u4e0b\u306e\u4e88\u9632\u3084\u3001\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u5411\u4e0a\u304c\u53ef\u80fd\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>17. \u907a\u4f1d\u5b50\u30d9\u30fc\u30b9\u306e\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30fb\u30d5\u30a3\u30c3\u30c8\u30cd\u30b9\u306e\u672a\u6765<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30fb\u30d5\u30a3\u30c3\u30c8\u30cd\u30b9\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u958b\u767a\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>AI\u3092\u6d3b\u7528\u3057\u305f\u907a\u4f1d\u5b50\u89e3\u6790\u3068\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<p>AI\u6280\u8853\u3092\u6d3b\u7528\u3057\u3066\u3001\u500b\u4eba\u306e\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u89e3\u6790\u3057\u3001\u6700\u9069\u306a\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u4f5c\u6210\u3059\u308b\u8a66\u307f\u304c\u59cb\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u30b7\u30b9\u30c6\u30e0\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u907a\u4f1d\u5b50\u00d7\u74b0\u5883\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u3057\u305f\u904b\u52d5\u51e6\u65b9\u30b7\u30b9\u30c6\u30e0<\/strong><\/li>\n\n\n\n<li><strong>AI\u304c\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u30d5\u30a3\u30fc\u30c9\u30d0\u30c3\u30af\u3092\u63d0\u4f9b\u3059\u308b\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30fb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/li>\n\n\n\n<li><strong>\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u6804\u990a\u7ba1\u7406\u3068\u904b\u52d5\u306e\u7d44\u307f\u5408\u308f\u305b\u6700\u9069\u5316<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6700\u65b0\u306e\u7814\u7a76\u3068\u5c55\u671b<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7879245\/\">Epigenetics and Physical Activity: Future Directions<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41467-020-19115-4\">Role of Myostatin in Exercise and Muscle Growth<\/a><\/li>\n\n\n\n<li>Gut Microbiota and Exercise: Emerging Insights<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>18. \u907a\u4f1d\u5b50\u3068\u904b\u52d5\u4e0d\u8db3\u306b\u3088\u308b\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u5909\u5316<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31748166_m-1024x585.jpg\" alt=\"\" class=\"wp-image-9460\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31748166_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31748166_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31748166_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31748166_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31748166_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u904b\u52d5\u306f\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u304c\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u7279\u5b9a\u306e\u30db\u30eb\u30e2\u30f3\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u3001\u4ee3\u8b1d\u7570\u5e38\u3084\u7cbe\u795e\u7684\u306a\u554f\u984c\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\uff08\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\uff09\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>NR3C1\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u904b\u52d5\u4e0d\u8db3\u306e\u4eba\u3067\u306f\u3001\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u5206\u6ccc\u304c\u6162\u6027\u7684\u306b\u5897\u52a0\u3057\u3001\u6b21\u306e\u3088\u3046\u306a\u5f71\u97ff\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8102\u80aa\u306e\u84c4\u7a4d<\/strong>\uff08\u7279\u306b\u5185\u81d3\u8102\u80aa\u306e\u5897\u52a0\uff09<\/li>\n\n\n\n<li><strong>\u8840\u7cd6\u5024\u306e\u4e0a\u6607<\/strong>\uff08\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u306e\u5897\u52a0\uff09<\/li>\n\n\n\n<li><strong>\u6162\u6027\u708e\u75c7\u306e\u4fc3\u9032<\/strong>\uff08\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u30ea\u30b9\u30af\u4e0a\u6607\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u9069\u5ea6\u306a\u904b\u52d5\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u30ec\u30d9\u30eb\u304c\u9069\u5207\u306b\u8abf\u6574\u3055\u308c\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u304c\u5411\u4e0a\u3059\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3068\u7b4b\u529b\u7dad\u6301<\/strong><\/h3>\n\n\n\n<p><strong>AR\uff08\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306e\u4f5c\u7528\u3092\u8abf\u7bc0\u3059\u308b\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306e\u5206\u6ccc\u304c\u6e1b\u5c11\u3057\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5f71\u97ff\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7b4b\u529b\u3068\u7b4b\u91cf\u306e\u4f4e\u4e0b<\/strong><\/li>\n\n\n\n<li><strong>\u4ee3\u8b1d\u306e\u4f4e\u4e0b\u3068\u80a5\u6e80\u30ea\u30b9\u30af\u306e\u5897\u52a0<\/strong><\/li>\n\n\n\n<li><strong>\u6027\u6b32\u306e\u6e1b\u5c11\u3068\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u4e71\u308c<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u7279\u306b\u7537\u6027\u3067\u306f\u3001\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff09\u304c\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306e\u5206\u6ccc\u3092\u4fc3\u9032\u3057\u3001\u5065\u5eb7\u7dad\u6301\u306b\u5f79\u7acb\u3064\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>19. \u904b\u52d5\u4e0d\u8db3\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u306e\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u3092\u5411\u4e0a\u3055\u305b\u3001\u7cd6\u5c3f\u75c5\u306e\u4e88\u9632\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u304c\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u304c\u9ad8\u307e\u308a\u3001\u8840\u7cd6\u5024\u306e\u8abf\u7bc0\u304c\u56f0\u96e3\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>TCF7L2\u907a\u4f1d\u5b50\u3068\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af<\/strong><\/h3>\n\n\n\n<p><strong>TCF7L2\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u8840\u7cd6\u8abf\u7bc0\u306b\u95a2\u4e0e\u3059\u308b\u8ee2\u5199\u56e0\u5b50\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u5909\u5316\u3057\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u554f\u984c\u304c\u767a\u751f\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8840\u7cd6\u5024\u306e\u4e0a\u6607<\/strong>\uff08\u98df\u5f8c\u9ad8\u8840\u7cd6\u306e\u30ea\u30b9\u30af\u5897\u52a0\uff09<\/li>\n\n\n\n<li><strong>\u81b5\u81d3\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4f4e\u4e0b<\/strong><\/li>\n\n\n\n<li><strong>\u5185\u81d3\u8102\u80aa\u306e\u84c4\u7a4d<\/strong>\uff08\u8102\u80aa\u809d\u306e\u30ea\u30b9\u30af\u4e0a\u6607\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u6709\u9178\u7d20\u904b\u52d5\u3084\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001TCF7L2\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u8efd\u6e1b\u3057\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>20. \u907a\u4f1d\u5b50\u3068\u904b\u52d5\u4e0d\u8db3\u306b\u3088\u308b\u514d\u75ab\u529b\u306e\u4f4e\u4e0b<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u306f\u514d\u75ab\u6a5f\u80fd\u3092\u8abf\u7bc0\u3057\u3001\u611f\u67d3\u75c7\u3084\u6162\u6027\u75be\u60a3\u306e\u4e88\u9632\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001\u514d\u75ab\u7cfb\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>HLA\u907a\u4f1d\u5b50\u3068\u514d\u75ab\u5fdc\u7b54<\/strong><\/h3>\n\n\n\n<p><strong>HLA\uff08\u30d2\u30c8\u767d\u8840\u7403\u6297\u539f\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u514d\u75ab\u7cfb\u306e\u50cd\u304d\u3092\u6c7a\u5b9a\u3059\u308b\u91cd\u8981\u306a\u907a\u4f1d\u5b50\u7fa4\u3067\u3059\u3002\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001HLA\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u4f4e\u4e0b\u3057\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5f71\u97ff\u304c\u751f\u3058\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u611f\u67d3\u75c7\u306b\u304b\u304b\u308a\u3084\u3059\u304f\u306a\u308b<\/strong>\uff08\u7279\u306b\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\uff09<\/li>\n\n\n\n<li><strong>\u708e\u75c7\u6027\u75be\u60a3\u306e\u30ea\u30b9\u30af\u5897\u52a0<\/strong>\uff08\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u60aa\u5316\uff09<\/li>\n\n\n\n<li><strong>\u8178\u5185\u7d30\u83cc\u30d0\u30e9\u30f3\u30b9\u306e\u4e71\u308c\u306b\u3088\u308b\u514d\u75ab\u6a5f\u80fd\u4f4e\u4e0b<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u9069\u5ea6\u306a\u904b\u52d5\u3092\u884c\u3046\u3053\u3068\u3067\u3001HLA\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u7dad\u6301\u3055\u308c\u3001\u514d\u75ab\u529b\u304c\u5411\u4e0a\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>21. \u904b\u52d5\u4e0d\u8db3\u304c\u3082\u305f\u3089\u3059\u7761\u7720\u969c\u5bb3\u3068\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/22782532_m-1024x683.jpg\" alt=\"\" class=\"wp-image-8878\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22782532_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22782532_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22782532_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22782532_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22782532_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u7761\u7720\u306f\u5065\u5eb7\u7dad\u6301\u306b\u4e0d\u53ef\u6b20\u3067\u3059\u304c\u3001\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u7761\u7720\u306e\u8cea\u304c\u4f4e\u4e0b\u3057\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3084\u4ee3\u8b1d\u6a5f\u80fd\u306b\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>CLOCK\u907a\u4f1d\u5b50\u3068\u4f53\u5185\u6642\u8a08<\/strong><\/h3>\n\n\n\n<p><strong>CLOCK\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u4f53\u5185\u6642\u8a08\u3092\u8abf\u7bc0\u3059\u308b\u907a\u4f1d\u5b50\u3067\u3042\u308a\u3001\u7761\u7720\u306e\u30ea\u30ba\u30e0\u3084\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u904b\u52d5\u4e0d\u8db3\u304c\u7d9a\u304f\u3068\u3001CLOCK\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u5909\u5316\u3057\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u554f\u984c\u304c\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5bdd\u3064\u304d\u304c\u60aa\u304f\u306a\u308b\uff08\u4e0d\u7720\u75c7\uff09<\/strong><\/li>\n\n\n\n<li><strong>\u6df1\u3044\u7761\u7720\u304c\u6e1b\u5c11\u3057\u3001\u75b2\u52b4\u56de\u5fa9\u304c\u9045\u308c\u308b<\/strong><\/li>\n\n\n\n<li><strong>\u30e1\u30e9\u30c8\u30cb\u30f3\u5206\u6ccc\u306e\u6e1b\u5c11\u306b\u3088\u308b\u7761\u7720\u306e\u8cea\u306e\u4f4e\u4e0b<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u9069\u5ea6\u306a\u904b\u52d5\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u4f53\u5185\u6642\u8a08\u304c\u30ea\u30bb\u30c3\u30c8\u3055\u308c\u3001\u7761\u7720\u306e\u8cea\u304c\u5411\u4e0a\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>22. \u6700\u65b0\u306e\u907a\u4f1d\u5b50\u7814\u7a76\u3068\u904b\u52d5\u4e0d\u8db3\u5bfe\u7b56<\/strong><\/h2>\n\n\n\n<p>\u6700\u65b0\u306e\u7814\u7a76\u3067\u306f\u3001\u904b\u52d5\u4e0d\u8db3\u3068\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u95a2\u4fc2\u306b\u3064\u3044\u3066\u3001\u3088\u308a\u8a73\u7d30\u306a\u30c7\u30fc\u30bf\u304c\u84c4\u7a4d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306e\u7814\u7a76\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41576-022-00587-4\"><strong>Exercise and Epigenetics: How Physical Activity Shapes Our Genes<\/strong><\/a><\/li>\n\n\n\n<li><strong>Physical Activity and Genetic Predisposition: Insights from Large-Scale GWAS Studies<\/strong><\/li>\n\n\n\n<li><strong>Impact of Sedentary Lifestyle on Metabolic Gene Expression<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u907a\u4f1d\u5b50\u3068\u904b\u52d5\u306e\u95a2\u4fc2\u304c\u307e\u3059\u307e\u3059\u660e\u78ba\u306b\u306a\u308a\u3001\u500b\u5225\u5316\u533b\u7642\u3084\u907a\u4f1d\u5b50\u30d9\u30fc\u30b9\u306e\u5065\u5eb7\u7ba1\u7406\u304c\u9032\u5c55\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>\u307e\u3068\u3081<\/strong><\/p>\n\n\n\n<p>\u904b\u52d5\u4e0d\u8db3\u306f\u5358\u306a\u308b\u4f53\u529b\u4f4e\u4e0b\u306b\u3068\u3069\u307e\u3089\u305a\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u3084\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306b\u6df1\u523b\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3084\u30c6\u30ed\u30e1\u30a2\u77ed\u7e2e\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u4e71\u308c\u3001\u514d\u75ab\u529b\u306e\u4f4e\u4e0b\u306a\u3069\u3001\u591a\u5c90\u306b\u308f\u305f\u308b\u5065\u5eb7\u30ea\u30b9\u30af\u304c\u904b\u52d5\u4e0d\u8db3\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u9069\u5ea6\u306a\u904b\u52d5\u3092\u7d99\u7d9a\u3059\u308b\u3053\u3068\u3067\u3001\u3053\u308c\u3089\u306e\u907a\u4f1d\u7684\u5f71\u97ff\u3092\u8efd\u6e1b\u3057\u3001\u5065\u5eb7\u5bff\u547d\u3092\u5ef6\u3070\u3059\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u4eca\u5f8c\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3084AI\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u533b\u7642\u304c\u9032\u3080\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u63d0\u4f9b\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u904b\u52d5\u4e0d\u8db3\u304c\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3084\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306b\u53ca\u307c\u3059\u5f71\u97ff\u306f\u591a\u5c90\u306b\u308f\u305f\u308a\u3001\u4ee3\u8b1d\u7570\u5e38\u3001\u7b4b\u840e\u7e2e\u3001\u514d\u75ab\u529b\u4f4e\u4e0b\u3001\u7761\u7720\u969c\u5bb3\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u5065\u5eb7\u30ea\u30b9\u30af\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u9069\u5207\u306a\u904b\u52d5\u7fd2\u6163\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u306e\u6539\u5584\u3084\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u8abf\u6574\u3001\u514d\u75ab\u6a5f\u80fd\u306e\u5f37\u5316\u304c\u53ef\u80fd\u3068\u306a\u308a\u307e\u3059\u3002\u4eca\u5f8c\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3084AI\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u767a\u5c55\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u79d1\u5b66\u7684\u6839\u62e0\u306b\u57fa\u3065\u3044\u305f\u5065\u5eb7\u7ba1\u7406\u304c\u5b9f\u73fe\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> 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