{"id":10172,"date":"2025-03-17T07:42:37","date_gmt":"2025-03-17T07:42:37","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=10172"},"modified":"2025-03-17T07:42:38","modified_gmt":"2025-03-17T07:42:38","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e7%97%85%e6%b0%97%e3%81%ae%e4%ba%88%e9%98%b2%e7%ad%96%ef%bc%9a%e5%80%8b%e4%ba%ba%e3%81%ab%e5%90%88%e3%81%a3%e3%81%9f%e5%81%a5%e5%ba%b7%e7%b6%ad%e6%8c%81%e6%b3%95","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e7%97%85%e6%b0%97%e3%81%ae%e4%ba%88%e9%98%b2%e7%ad%96%ef%bc%9a%e5%80%8b%e4%ba%ba%e3%81%ab%e5%90%88%e3%81%a3%e3%81%9f%e5%81%a5%e5%ba%b7%e7%b6%ad%e6%8c%81%e6%b3%95\/","title":{"rendered":"\u907a\u4f1d\u5b50\u3068\u75c5\u6c17\u306e\u4e88\u9632\u7b56\uff1a\u500b\u4eba\u306b\u5408\u3063\u305f\u5065\u5eb7\u7dad\u6301\u6cd5"},"content":{"rendered":"\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u3068\u75c5\u6c17\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u79c1\u305f\u3061\u306e\u4f53\u3092\u69cb\u6210\u3059\u308b\u7d30\u80de\u306b\u306fDNA\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001DNA\u306b\u306f\u7d042\u4e07\u7a2e\u985e\u306e\u907a\u4f1d\u5b50\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306f\u79c1\u305f\u3061\u306e\u4f53\u8cea\u3084\u75c5\u6c17\u306e\u30ea\u30b9\u30af\u306b\u6df1\u304f\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u306f\u4e21\u89aa\u304b\u3089\u53d7\u3051\u7d99\u304c\u308c\u308b\u305f\u3081\u3001\u7279\u5b9a\u306e\u75be\u60a3\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3082\u907a\u4f1d\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001<strong>BRCA1\u304a\u3088\u3073BRCA2\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u306f\u3001\u4e73\u304c\u3093\u3084\u5375\u5de3\u304c\u3093\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u5927\u5e45\u306b\u9ad8\u3081\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.cancer.gov\/\">National Cancer Institute<\/a>\uff09\u3002\u540c\u69d8\u306b\u3001<strong>APOE\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570<\/strong>\u306f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3068\u95a2\u9023\u304c\u3042\u308a\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.alz.org\/\">Alzheimer\u2019s Association<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u3059\u3079\u3066\u306e\u75c5\u6c17\u304c\u907a\u4f1d\u5b50\u3060\u3051\u3067\u6c7a\u307e\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<strong>\u751f\u6d3b\u7fd2\u6163\u3084\u74b0\u5883\u8981\u56e0<\/strong>\u3082\u75c5\u6c17\u306e\u767a\u75c7\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u4f8b\u3048\u3070\u30012\u578b\u7cd6\u5c3f\u75c5\u306f\u907a\u4f1d\u7684\u8981\u56e0\u3068\u3068\u3082\u306b\u98df\u751f\u6d3b\u3084\u904b\u52d5\u7fd2\u6163\u304c\u91cd\u8981\u306a\u8981\u7d20\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u4e88\u9632\u533b\u7642\u306e\u73fe\u72b6<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u306e\u6280\u8853\u9769\u65b0\u306b\u3088\u308a\u3001\u500b\u4eba\u306e\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u4e88\u9632\u533b\u7642\u304c\u9032\u5c55\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001<strong>\u30b2\u30ce\u30e0\u89e3\u6790\u6280\u8853<\/strong>\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u6bd4\u8f03\u7684\u5b89\u4fa1\u306b\u500b\u4eba\u306e\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u89e3\u6790\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u5c06\u6765\u7684\u306b\u304b\u304b\u308a\u3084\u3059\u3044\u75c5\u6c17\u3092\u4e88\u6e2c\u3057\u3001\u4e88\u9632\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u65e5\u672c\u3067\u306f**\u300c\u304c\u3093\u30b2\u30ce\u30e0\u533b\u7642\u300d**\u304c\u6ce8\u76ee\u3055\u308c\u3066\u304a\u308a\u3001\u304c\u3093\u60a3\u8005\u306e\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u89e3\u6790\u3059\u308b\u3053\u3068\u3067\u3001\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u3092\u9078\u629e\u3059\u308b\u8a66\u307f\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a\u56fd\u7acb\u304c\u3093\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\uff09\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u88fd\u85ac\u696d\u754c\u3067\u306f**\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u57fa\u3065\u3044\u305f\u500b\u5225\u5316\u533b\u7642\uff08Precision Medicine\uff09**\u304c\u958b\u767a\u3055\u308c\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u60a3\u8005\u306b\u6700\u9069\u306a\u85ac\u5264\u3092\u51e6\u65b9\u3059\u308b\u3053\u3068\u3067\u3001\u526f\u4f5c\u7528\u3092\u6291\u3048\u3064\u3064\u52b9\u679c\u7684\u306a\u6cbb\u7642\u3092\u5b9f\u73fe\u3059\u308b\u8a66\u307f\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7a2e\u985e\u3068\u305d\u306e\u610f\u7fa9<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/39689_s.jpg\" alt=\"DNA\" class=\"wp-image-1188\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/39689_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/39689_s-300x200.jpg 300w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u9069\u5207\u306a\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002\u73fe\u5728\u3001\u5229\u7528\u3055\u308c\u3066\u3044\u308b\u4e3b\u306a\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u8a3a\u65ad\u76ee\u7684\u306e\u907a\u4f1d\u5b50\u691c\u67fb<\/strong><\/h3>\n\n\n\n<p>\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u75c5\u6c17\u306e\u8a3a\u65ad\u3092\u884c\u3046\u691c\u67fb\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u304c\u3093\u306e\u6cbb\u7642\u65b9\u91dd\u3092\u6c7a\u5b9a\u3059\u308b\u305f\u3081\u306b\u3001<strong>\u907a\u4f1d\u5b50\u30d1\u30cd\u30eb\u691c\u67fb<\/strong>\u304c\u884c\u308f\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u75be\u60a3\u30ea\u30b9\u30af\u8a55\u4fa1\u306e\u305f\u3081\u306e\u907a\u4f1d\u5b50\u691c\u67fb<\/strong><\/h3>\n\n\n\n<p>\u7279\u5b9a\u306e\u75c5\u6c17\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306b\u884c\u308f\u308c\u308b\u691c\u67fb\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u5fc3\u75be\u60a3\u3084\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306e**\u591a\u907a\u4f1d\u5b50\u30ea\u30b9\u30af\u30b9\u30b3\u30a2\uff08PRS\uff09**\u304c\u3042\u308a\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/ng\/\">Nature Genetics<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u85ac\u7406\u907a\u4f1d\u5b66\u7684\u691c\u67fb<\/strong><\/h3>\n\n\n\n<p>\u85ac\u306e\u4ee3\u8b1d\u3084\u52b9\u679c\u306e\u9055\u3044\u3092\u8abf\u3079\u308b\u305f\u3081\u306e\u691c\u67fb\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>CYP2C19\u907a\u4f1d\u5b50\u306e\u691c\u67fb<\/strong>\u306f\u3001\u6297\u8840\u5c0f\u677f\u85ac\u306e\u52b9\u679c\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306b\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff084\uff09\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u95a2\u9023\u306e\u907a\u4f1d\u5b50\u691c\u67fb<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u7684\u306a\u4f53\u8cea\uff08\u80a5\u6e80\u3001\u904b\u52d5\u80fd\u529b\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u8010\u6027\u306a\u3069\uff09\u3092\u8abf\u3079\u308b\u691c\u67fb\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u500b\u4eba\u306b\u5408\u3063\u305f\u751f\u6d3b\u7fd2\u6163\u306e\u9078\u629e\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u5065\u5eb7\u7dad\u6301\u6cd5<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u57fa\u306b\u3001\u500b\u4eba\u306b\u5408\u3063\u305f\u5065\u5eb7\u7dad\u6301\u6cd5\u3092\u5b9f\u8df5\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u4ee5\u4e0b\u306f\u5177\u4f53\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u4f8b\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u98df\u4e8b\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u7684\u306b<strong>\u8102\u8cea\u4ee3\u8b1d\u304c\u82e6\u624b\u306a\u4eba<\/strong>\u306f\u3001\u4f4e\u8102\u80aa\u98df\u3092\u610f\u8b58\u3059\u308b\u3068\u5065\u5eb7\u7dad\u6301\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u9006\u306b\u3001<strong>\u7cd6\u4ee3\u8b1d\u304c\u5f31\u3044\u4eba<\/strong>\u306f\u70ad\u6c34\u5316\u7269\u3092\u63a7\u3048\u3081\u306b\u3059\u308b\u3053\u3068\u3067\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u904b\u52d5\u306e\u30ab\u30b9\u30bf\u30de\u30a4\u30ba<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066<strong>\u6301\u4e45\u529b\u578b\u3068\u77ac\u767a\u529b\u578b<\/strong>\u306e\u9055\u3044\u304c\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001ACTN3\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3088\u3063\u3066\u3001\u77ed\u8ddd\u96e2\u8d70\u5411\u304d\u304b\u9577\u8ddd\u96e2\u8d70\u5411\u304d\u304b\u304c\u7570\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u9069\u3057\u305f\u904b\u52d5\u3092\u9078\u3076\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306b\u95a2\u308f\u308b<strong>COMT\u907a\u4f1d\u5b50<\/strong>\u306e\u30bf\u30a4\u30d7\u306b\u3088\u3063\u3066\u3001\u30b9\u30c8\u30ec\u30b9\u3078\u306e\u53cd\u5fdc\u304c\u7570\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u3092\u8003\u616e\u3057\u3001\u9069\u5207\u306a\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u6cd5\uff08\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u3001\u7791\u60f3\u306a\u3069\uff09\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff084\uff09\u7761\u7720\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<p>\u7761\u7720\u306e\u8cea\u306b\u95a2\u4fc2\u3059\u308b<strong>PER3\u907a\u4f1d\u5b50<\/strong>\u306e\u9055\u3044\u306b\u3088\u308a\u3001<strong>\u671d\u578b\u304b\u591c\u578b\u304b<\/strong>\u304c\u6c7a\u307e\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u60c5\u5831\u3092\u57fa\u306b\u6700\u9069\u306a\u751f\u6d3b\u30ea\u30ba\u30e0\u3092\u69cb\u7bc9\u3059\u308b\u3053\u3068\u3067\u3001\u5065\u5eb7\u7dad\u6301\u306b\u3064\u306a\u3052\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u907a\u4f1d\u5b50\u60c5\u5831\u6d3b\u7528\u306e\u8ab2\u984c\u3068\u5c55\u671b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-1024x683.jpg\" alt=\"\u672a\u6765\u306e\u533b\u7642\" class=\"wp-image-1075\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u6d3b\u7528\u306b\u306f\u5927\u304d\u306a\u53ef\u80fd\u6027\u304c\u3042\u308b\u4e00\u65b9\u3067\u3001\u3044\u304f\u3064\u304b\u306e\u8ab2\u984c\u3082\u5b58\u5728\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u502b\u7406\u7684\u554f\u984c\u3068\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u4fdd\u8b77<\/strong><strong><br><\/strong> \u907a\u4f1d\u5b50\u60c5\u5831\u306f\u6975\u3081\u3066\u500b\u4eba\u7684\u306a\u30c7\u30fc\u30bf\u3067\u3042\u308a\u3001<strong>\u60c5\u5831\u306e\u53d6\u308a\u6271\u3044\u3084\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u4fdd\u8b77<\/strong>\u304c\u91cd\u8981\u306a\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u4fdd\u967a\u4f1a\u793e\u3084\u96c7\u7528\u4e3b\u306b\u3088\u308b\u5dee\u5225\u306e\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u306e\u8b70\u8ad6\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.who.int\/\">WHO<\/a>\uff09\u3002<br><\/li>\n\n\n\n<li><strong>\u79d1\u5b66\u7684\u6839\u62e0\u306e\u84c4\u7a4d\u4e0d\u8db3<\/strong><strong><br><\/strong> \u4e00\u90e8\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u307e\u3060\u79d1\u5b66\u7684\u6839\u62e0\u304c\u4e0d\u5341\u5206\u3067\u3042\u308a\u3001\u78ba\u5b9f\u306a\u4e88\u6e2c\u304c\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u306e\u305f\u3081\u3001\u7d50\u679c\u3092\u904e\u4fe1\u305b\u305a\u3001\u5c02\u9580\u5bb6\u306e\u52a9\u8a00\u3092\u53d7\u3051\u306a\u304c\u3089\u6d3b\u7528\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u6280\u8853\u9769\u65b0\u306b\u3088\u308b\u65b0\u305f\u306a\u53ef\u80fd\u6027<\/strong><strong><br><\/strong> AI\u3068\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u306e\u767a\u5c55\u306b\u3088\u308a\u3001<strong>\u3088\u308a\u7cbe\u5ea6\u306e\u9ad8\u3044\u4e88\u6e2c\u3068\u500b\u5225\u5316\u533b\u7642<\/strong>\u304c\u5b9f\u73fe\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4eca\u5f8c\u3001\u3055\u3089\u306b\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u75c5\u6c17\u4e88\u9632\u304c\u4e00\u822c\u5316\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u907a\u4f1d\u5b50\u3068\u74b0\u5883\u306e\u76f8\u4e92\u4f5c\u7528<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u304c\u75c5\u6c17\u306e\u767a\u75c7\u306b\u95a2\u4e0e\u3059\u308b\u4e00\u65b9\u3067\u3001\u74b0\u5883\u8981\u56e0\u3082\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002**\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\uff08\u5f8c\u6210\u907a\u4f1d\u5b66\uff09**\u306e\u7814\u7a76\u306b\u3088\u308c\u3070\u3001\u751f\u6d3b\u7fd2\u6163\u3084\u30b9\u30c8\u30ec\u30b9\u3001\u98df\u4e8b\u306a\u3069\u306e\u74b0\u5883\u8981\u56e0\u304c\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u98df\u4e8b\u304c\u907a\u4f1d\u5b50\u306b\u4e0e\u3048\u308b\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>\u98df\u751f\u6d3b\u306f\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>\u8449\u9178\u3084\u30d3\u30bf\u30df\u30f3B12<\/strong>\u306fDNA\u306e\u30e1\u30c1\u30eb\u5316\uff08\u907a\u4f1d\u5b50\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u30aa\u30f3\u30fb\u30aa\u30d5\u3059\u308b\u4ed5\u7d44\u307f\uff09\u306b\u95a2\u4e0e\u3057\u3001\u304c\u3093\u3084\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/nrg\/\">Nature Reviews Genetics<\/a>\uff09\u3002\u307e\u305f\u3001<strong>\u30aa\u30e1\u30ac3\u8102\u80aa\u9178<\/strong>\u304c\u708e\u75c7\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u904b\u52d5\u3068\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u904b\u52d5\u306f\u7b4b\u8089\u3092\u935b\u3048\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306b\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u7279\u306b\u3001<strong>PPARGC1A\u907a\u4f1d\u5b50<\/strong>\u306f\u6301\u4e45\u529b\u3092\u9ad8\u3081\u308b\u907a\u4f1d\u5b50\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u6709\u9178\u7d20\u904b\u52d5\u306b\u3088\u3063\u3066\u305d\u306e\u767a\u73fe\u304c\u4fc3\u9032\u3055\u308c\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u904b\u52d5\u306b\u3088\u308b\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306e\u5411\u4e0a\u306f**BDNF\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09**\u306e\u767a\u73fe\u5897\u52a0\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u30b9\u30c8\u30ec\u30b9\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u6162\u6027\u7684\u306a\u30b9\u30c8\u30ec\u30b9\u306f\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u75c5\u6c17\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u95a2\u9023\u3059\u308b<strong>NR3C1\u907a\u4f1d\u5b50<\/strong>\u306e\u30e1\u30c1\u30eb\u5316\u306f\u3001\u3046\u3064\u75c5\u3084\u4e0d\u5b89\u969c\u5bb3\u3068\u95a2\u4fc2\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u5e7c\u5c11\u671f\u306e\u30c8\u30e9\u30a6\u30de\u304c\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/mp\/\">Molecular Psychiatry<\/a>\uff09\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u907a\u4f1d\u5b50\u89e3\u6790\u6280\u8853\u306e\u9032\u6b69\u3068\u305d\u306e\u5fdc\u7528<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"766\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/31783250_m-1024x766.jpg\" alt=\"\" class=\"wp-image-8214\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31783250_m-1024x766.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31783250_m-300x224.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31783250_m-768x575.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31783250_m.jpg 1176w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u89e3\u6790\u6280\u8853\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u500b\u4eba\u306e\u30b2\u30ce\u30e0\u60c5\u5831\u3092\u624b\u8efd\u306b\u89e3\u6790\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u4ee5\u4e0b\u306f\u4e3b\u306a\u907a\u4f1d\u5b50\u89e3\u6790\u6280\u8853\u306e\u6982\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09<\/strong><\/h3>\n\n\n\n<p>NGS\u306f\u3001\u5927\u91cf\u306eDNA\u3092\u77ed\u6642\u9593\u3067\u89e3\u6790\u3067\u304d\u308b\u6280\u8853\u3067\u3001<strong>\u304c\u3093\u30b2\u30ce\u30e0\u533b\u7642\u3084\u5e0c\u5c11\u75be\u60a3\u306e\u8a3a\u65ad<\/strong>\u306b\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u65e5\u672c\u306e<strong>\u304c\u3093\u30b2\u30ce\u30e0\u533b\u7642\u63a8\u9032\u30b3\u30f3\u30bd\u30fc\u30b7\u30a2\u30e0<\/strong>\u3067\u306f\u3001\u60a3\u8005\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u89e3\u6790\u3057\u3001\u9069\u5207\u306a\u6cbb\u7642\u6cd5\u3092\u63d0\u4f9b\u3059\u308b\u53d6\u308a\u7d44\u307f\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a\u56fd\u7acb\u304c\u3093\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09CRISPR-Cas9\u306b\u3088\u308b\u907a\u4f1d\u5b50\u7de8\u96c6<\/strong><\/h3>\n\n\n\n<p>CRISPR\u6280\u8853\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3092\u72d9\u3063\u3066\u6539\u5909\u3067\u304d\u308b\u6280\u8853\u3067\u3042\u308a\u3001\u907a\u4f1d\u6027\u75be\u60a3\u306e\u6cbb\u7642\u3084\u65b0\u85ac\u958b\u767a\u306b\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>\u938c\u72b6\u8d64\u8840\u7403\u75c7<\/strong>\u306e\u6cbb\u7642\u306bCRISPR\u304c\u6d3b\u7528\u3055\u308c\u3066\u304a\u308a\u3001\u3059\u3067\u306b\u81e8\u5e8a\u8a66\u9a13\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u30d1\u30fc\u30bd\u30ca\u30eb\u30b2\u30ce\u30e0\u89e3\u6790<\/strong><\/h3>\n\n\n\n<p>\u4e00\u822c\u6d88\u8cbb\u8005\u5411\u3051\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u30b5\u30fc\u30d3\u30b9\u304c\u5897\u3048\u3001\u500b\u4eba\u306e\u75be\u60a3\u30ea\u30b9\u30af\u3084\u4f53\u8cea\u3092\u77e5\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u4f8b\u3048\u3070\u3001<strong>23andMe<\/strong>\u3084<strong>GeneLife<\/strong>\u306a\u3069\u306e\u4f01\u696d\u304c\u63d0\u4f9b\u3059\u308b\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u3001\u80a5\u6e80\u30ea\u30b9\u30af\u3084\u30a2\u30eb\u30b3\u30fc\u30eb\u5206\u89e3\u80fd\u529b\u306a\u3069\u3092\u5206\u6790\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u4e88\u9632<\/strong><\/h2>\n\n\n\n<p>\u751f\u6d3b\u7fd2\u6163\u75c5\u306f\u907a\u4f1d\u3068\u74b0\u5883\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u767a\u75c7\u3059\u308b\u305f\u3081\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3088\u308a\u52b9\u679c\u7684\u306a\u4e88\u9632\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u7cd6\u5c3f\u75c5<\/strong><\/h3>\n\n\n\n<p>\u7cd6\u5c3f\u75c5\u306e\u767a\u75c7\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u3068\u751f\u6d3b\u7fd2\u6163\u304c\u5f71\u97ff\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>TCF7L2\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u306f2\u578b\u7cd6\u5c3f\u75c5\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u9069\u5207\u306a\u98df\u4e8b\u3068\u904b\u52d5\u3067\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3067\u304d\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/diabetesjournals.org\/\">Diabetes Journal<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u9ad8\u8840\u5727<\/strong><\/h3>\n\n\n\n<p>\u9ad8\u8840\u5727\u306b\u306f<strong>ACE\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u304c\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u578b\u306b\u3088\u3063\u3066\u5869\u5206\u611f\u53d7\u6027\u304c\u7570\u306a\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u5869\u5206\u6442\u53d6\u3092\u5236\u9650\u3059\u308b\u3053\u3068\u3067\u3001\u9ad8\u8840\u5727\u306e\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u8102\u8cea\u7570\u5e38\u75c7<\/strong><\/h3>\n\n\n\n<p><strong>APOA5\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u306f\u8102\u8cea\u4ee3\u8b1d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u4e2d\u6027\u8102\u80aa\u304c\u9ad8\u304f\u306a\u308a\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u4eba\u306f\u3001\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3092\u542b\u3080\u98df\u54c1\uff08\u9752\u9b5a\u3001\u4e9c\u9ebb\u4ec1\u6cb9\u306a\u3069\uff09\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u8102\u8cea\u7570\u5e38\u75c7\u306e\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u907a\u4f1d\u5b50\u691c\u67fb\u3068\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31715672_m-1024x683.jpg\" alt=\"\u30d1\u30ef\u30cf\u30e9\u3092\u53d7\u3051\u308b\u5973\u6027\u4f1a\u793e\u54e1\" class=\"wp-image-9430\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31715672_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31715672_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31715672_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31715672_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31715672_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u6700\u8fd1\u306e\u7814\u7a76\u3067\u306f\u3001\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u9023\u6027\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u3046\u3064\u75c5\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u3046\u3064\u75c5\u306b\u306f**SLC6A4\u907a\u4f1d\u5b50\uff08\u30bb\u30ed\u30c8\u30cb\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u907a\u4f1d\u5b50\uff09**\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u654f\u611f\u3067\u3046\u3064\u75c5\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08\u53c2\u8003\uff1aJAMA Psychiatry\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306b\u306f<strong>COMT\u907a\u4f1d\u5b50<\/strong>\u304c\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u4eba\u306f\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\uff08\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\uff09\u306e\u5206\u6ccc\u304c\u904e\u5270\u306b\u306a\u308a\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u4e0d\u5b89\u969c\u5bb3\u3084\u30d1\u30cb\u30c3\u30af\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u8a8d\u77e5\u75c7\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u767a\u75c7\u30ea\u30b9\u30af\u306b\u306f<strong>APOE\u907a\u4f1d\u5b50<\/strong>\u304c\u95a2\u4fc2\u3057\u3066\u304a\u308a\u3001<strong>APOE4\u578b<\/strong>\u3092\u6301\u3064\u4eba\u306f\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u904b\u52d5\u3084\u5065\u5eb7\u7684\u306a\u98df\u4e8b\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.alz.org\/\">Alzheimer\u2019s Association<\/a>\uff09\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u907a\u4f1d\u5b50\u533b\u7642\u306e\u672a\u6765<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u4eca\u5f8c\u306f\u3088\u308a\u9ad8\u5ea6\u306a\u4e88\u9632\u7b56\u3084\u6cbb\u7642\u6cd5\u304c\u958b\u767a\u3055\u308c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001<strong>AI\u3092\u6d3b\u7528\u3057\u305f\u30b2\u30ce\u30e0\u30c7\u30fc\u30bf\u89e3\u6790<\/strong>\u304c\u9032\u307f\u3001\u3088\u308a\u7cbe\u5bc6\u306a\u500b\u5225\u5316\u533b\u7642\u304c\u5b9f\u73fe\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001<strong>\u907a\u4f1d\u5b50\u30ef\u30af\u30c1\u30f3\u306e\u958b\u767a<\/strong>\u3082\u9032\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u65b0\u3057\u3044\u611f\u67d3\u75c7\u3078\u306e\u5bfe\u5fdc\u7b56\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002COVID-19\u30ef\u30af\u30c1\u30f3\u306b\u4f7f\u308f\u308c\u305fmRNA\u6280\u8853\u306f\u3001\u5c06\u6765\u7684\u306b\u304c\u3093\u6cbb\u7642\u3084\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u6cbb\u7642\u306b\u3082\u5fdc\u7528\u3055\u308c\u308b\u898b\u8fbc\u307f\u3067\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nejm.org\/\">NEJM<\/a>\uff09\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. \u907a\u4f1d\u5b50\u3068\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"640\" height=\"447\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/2572508_s.jpg\" alt=\"DNA\" class=\"wp-image-1260\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/2572508_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/2572508_s-300x210.jpg 300w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306f\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u306b\u3082\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u79c1\u305f\u3061\u306e\u4f53\u304c\u75c5\u539f\u4f53\u306b\u3069\u306e\u3088\u3046\u306b\u53cd\u5fdc\u3059\u308b\u304b\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09HLA\u907a\u4f1d\u5b50\u3068\u81ea\u5df1\u514d\u75ab\u75be\u60a3<\/strong><\/h3>\n\n\n\n<p>HLA\uff08\u30d2\u30c8\u767d\u8840\u7403\u6297\u539f\uff09\u907a\u4f1d\u5b50\u306f\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u306e\u91cd\u8981\u306a\u8981\u7d20\u3067\u3042\u308a\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u767a\u75c7\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>HLA-B27\u907a\u4f1d\u5b50<\/strong>\u3092\u6301\u3064\u4eba\u306f\u5f37\u76f4\u6027\u810a\u690e\u708e\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u3001<strong>HLA-DR4\u907a\u4f1d\u5b50<\/strong>\u306f\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.jimmunol.org\/\">The Journal of Immunology<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u611f\u67d3\u75c7\u3078\u306e\u611f\u53d7\u6027<\/strong><\/h3>\n\n\n\n<p>\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u578b\u304c\u611f\u67d3\u75c7\u3078\u306e\u611f\u53d7\u6027\u3092\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>CCR5\u907a\u4f1d\u5b50\u5909\u7570<\/strong>\u3092\u6301\u3064\u4eba\u306fHIV\u611f\u67d3\u3092\u9632\u3050\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u4e00\u65b9\u3001<strong>TLR7\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u306fCOVID-19\u306e\u91cd\u75c7\u5316\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/nm\/\">Nature Medicine<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u30ef\u30af\u30c1\u30f3\u52b9\u679c\u306e\u500b\u4eba\u5dee<\/strong><\/h3>\n\n\n\n<p>\u30ef\u30af\u30c1\u30f3\u306e\u52b9\u679c\u306f\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>IL28B\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u306fB\u578b\u809d\u708e\u30ef\u30af\u30c1\u30f3\u306e\u514d\u75ab\u5fdc\u7b54\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u77e5\u898b\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u4eba\u3054\u3068\u306b\u6700\u9069\u306a\u30ef\u30af\u30c1\u30f3\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u69cb\u7bc9\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>12. \u907a\u4f1d\u5b50\u3068\u304c\u3093\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u304c\u3093\u306f\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u8981\u56e0\u304c\u8907\u96d1\u306b\u95a2\u4e0e\u3059\u308b\u75be\u60a3\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u304c\u3093\u6291\u5236\u907a\u4f1d\u5b50\u3068\u767a\u304c\u3093\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u304c\u3093\u306f\u3001**\u304c\u3093\u6291\u5236\u907a\u4f1d\u5b50\uff08\u4f8b\uff1aTP53, BRCA1\uff09**\u306e\u6a5f\u80fd\u55aa\u5931\u3084\u3001**\u767a\u304c\u3093\u907a\u4f1d\u5b50\uff08\u4f8b\uff1aKRAS, MYC\uff09**\u306e\u6d3b\u6027\u5316\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>TP53\u907a\u4f1d\u5b50\u5909\u7570<\/strong>\u306f\u591a\u304f\u306e\u304c\u3093\u3067\u767a\u898b\u3055\u308c\u3066\u304a\u308a\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u8a55\u4fa1\u306e\u91cd\u8981\u306a\u8981\u7d20\u3068\u306a\u3063\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1aCancer Research\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u5bb6\u65cf\u6027\u304c\u3093\u3068\u907a\u4f1d\u5b50\u691c\u67fb<\/strong><\/h3>\n\n\n\n<p>\u4e00\u90e8\u306e\u304c\u3093\u306f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u5f37\u304f\u5f71\u97ff\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>BRCA1\/BRCA2\u907a\u4f1d\u5b50\u5909\u7570<\/strong>\u306f\u4e73\u304c\u3093\u3068\u5375\u5de3\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u307e\u3059\u3002\u307e\u305f\u3001<strong>MLH1, MSH2, MSH6\u907a\u4f1d\u5b50\u5909\u7570<\/strong>\u306f\u30ea\u30f3\u30c1\u75c7\u5019\u7fa4\u3068\u95a2\u9023\u3057\u3001\u5927\u8178\u304c\u3093\u3084\u5b50\u5bae\u5185\u819c\u304c\u3093\u306e\u767a\u75c7\u30ea\u30b9\u30af\u304c\u4e0a\u6607\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u304c\u3093\u4e88\u9632\u306e\u305f\u3081\u306e\u907a\u4f1d\u5b50\u4ecb\u5165<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u304c\u3093\u306e\u4e88\u9632\u7b56\u3092\u5f37\u5316\u3067\u304d\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>\u9ad8\u30ea\u30b9\u30af\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong>\u306b\u5bfe\u3057\u3066\u306f\u3001\u5b9a\u671f\u7684\u306a\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u691c\u67fb\u3084\u4e88\u9632\u7684\u624b\u8853\u304c\u63a8\u5968\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>13. \u907a\u4f1d\u5b50\u3068\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"574\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/29974086_m-1024x574.jpg\" alt=\"\u30b9\u30ad\u30f3\u30b1\u30a2\u30fb\u5316\u7ca7\u6c34\u30fb\u4fdd\u6e7f\u306e\u30a4\u30e1\u30fc\u30b8\" class=\"wp-image-9636\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29974086_m-1024x574.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29974086_m-300x168.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29974086_m-768x430.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29974086_m-1536x861.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29974086_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8001\u5316\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u5bff\u547d\u3084\u5065\u5eb7\u5bff\u547d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u9577\u5bff\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u9577\u5bff\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u3068\u3057\u3066\u3001<strong>FOXO3\u907a\u4f1d\u5b50<\/strong>\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u52a0\u9f62\u95a2\u9023\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/onlinelibrary.wiley.com\/journal\/14749726\">Aging Cell<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u30c6\u30ed\u30e1\u30a2\u3068\u8001\u5316<\/strong><\/h3>\n\n\n\n<p>\u67d3\u8272\u4f53\u306e\u672b\u7aef\u306b\u3042\u308b<strong>\u30c6\u30ed\u30e1\u30a2<\/strong>\u306f\u7d30\u80de\u306e\u8001\u5316\u3068\u5bc6\u63a5\u306b\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002<strong>TERT\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u306f\u30c6\u30ed\u30e1\u30a2\u306e\u9577\u3055\u3092\u7dad\u6301\u3059\u308b\u5f79\u5272\u304c\u3042\u308a\u3001\u8001\u5316\u3092\u9045\u3089\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u8001\u5316\u306e\u907a\u4f1d\u5b50\u5236\u5fa1<\/strong><\/h3>\n\n\n\n<p>\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u3084\u7279\u5b9a\u306e\u6804\u990a\u7d20\uff08\u30ec\u30b9\u30d9\u30e9\u30c8\u30ed\u30fc\u30eb\u3001NMN\uff09\u304c<strong>SIRT1\u907a\u4f1d\u5b50<\/strong>\u3092\u6d3b\u6027\u5316\u3057\u3001\u8001\u5316\u3092\u9045\u3089\u305b\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u7814\u7a76\u306f\u3001\u907a\u4f1d\u5b50\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u305f\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u6226\u7565\u306e\u958b\u767a\u306b\u3064\u306a\u304c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>14. \u907a\u4f1d\u5b50\u7de8\u96c6\u3068\u672a\u6765\u306e\u533b\u7642<\/strong><\/h2>\n\n\n\n<p>CRISPR-Cas9\u306a\u3069\u306e\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306f\u3001\u907a\u4f1d\u6027\u75be\u60a3\u306e\u6cbb\u7642\u306b\u9769\u547d\u3092\u3082\u305f\u3089\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u9032\u5c55<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u3092\u7528\u3044\u305f\u6cbb\u7642\u6cd5\u306f\u3001\u3059\u3067\u306b\u81e8\u5e8a\u8a66\u9a13\u6bb5\u968e\u306b\u5165\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>\u938c\u72b6\u8d64\u8840\u7403\u75c7<\/strong>\u306e\u6cbb\u7642\u306bCRISPR\u3092\u5229\u7528\u3057\u305f\u907a\u4f1d\u5b50\u7de8\u96c6\u304c\u6210\u529f\u3057\u3001\u4e00\u90e8\u306e\u60a3\u8005\u304c\u6cbb\u7652\u3057\u305f\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u907a\u4f1d\u5b50\u30c9\u30e9\u30a4\u30d6\u3068\u611f\u67d3\u75c7\u5bfe\u7b56<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u30c9\u30e9\u30a4\u30d6\u6280\u8853\u3092\u5229\u7528\u3057\u3066\u3001\u868a\u306e\u7e41\u6b96\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u3001\u30de\u30e9\u30ea\u30a2\u306a\u3069\u306e\u611f\u67d3\u75c7\u3092\u6839\u7d76\u3059\u308b\u8a66\u307f\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6280\u8853\u304c\u6210\u529f\u3059\u308c\u3070\u3001\u516c\u8846\u885b\u751f\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.cell.com\/\">Cell<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u907a\u4f1d\u5b50\u502b\u7406\u3068\u793e\u4f1a\u7684\u8ab2\u984c<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306b\u306f\u502b\u7406\u7684\u306a\u8ab2\u984c\u3082\u4f34\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u300c\u30c7\u30b6\u30a4\u30ca\u30fc\u30d9\u30d3\u30fc\u300d\u306e\u554f\u984c\u3084\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u60aa\u7528\u306b\u5bfe\u3059\u308b\u61f8\u5ff5\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4eca\u5f8c\u3001\u6280\u8853\u306e\u767a\u5c55\u3068\u3068\u3082\u306b\u502b\u7406\u7684\u306a\u8b70\u8ad6\u3082\u9032\u3081\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>15. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u30d1\u30fc\u30bd\u30ca\u30eb\u30d8\u30eb\u30b9\u30b1\u30a2\u306e\u672a\u6765<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/30661311_m-1024x585.jpg\" alt=\"\u8a55\u5224\u306e\u533b\u8005\" class=\"wp-image-8392\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/30661311_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/30661311_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/30661311_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/30661311_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/30661311_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30d1\u30fc\u30bd\u30ca\u30eb\u30d8\u30eb\u30b9\u30b1\u30a2\u306f\u3001\u3088\u308a\u500b\u5225\u5316\u3055\u308c\u305f\u533b\u7642\u306e\u5b9f\u73fe\u306b\u5411\u3051\u3066\u767a\u5c55\u3092\u7d9a\u3051\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u500b\u5225\u5316\u533b\u7642\u306e\u9032\u5316<\/strong><\/h3>\n\n\n\n<p>\u30b2\u30ce\u30e0\u30c7\u30fc\u30bf\u3068AI\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u500b\u3005\u306e\u60a3\u8005\u306b\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u3092\u63d0\u6848\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u304c\u3093\u60a3\u8005\u306e\u907a\u4f1d\u5b50\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u89e3\u6790\u3057\u3001\u6700\u3082\u52b9\u679c\u7684\u306a\u85ac\u3092\u9078\u629e\u3059\u308b\u300c\u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30fb\u30e1\u30c7\u30a3\u30b7\u30f3\uff08\u7cbe\u5bc6\u533b\u7642\uff09\u300d\u304c\u666e\u53ca\u3057\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u30c7\u30b8\u30bf\u30eb\u30d8\u30eb\u30b9\u3068\u907a\u4f1d\u5b50\u60c5\u5831<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30de\u30fc\u30c8\u30a6\u30a9\u30c3\u30c1\u3084\u30a6\u30a7\u30a2\u30e9\u30d6\u30eb\u30c7\u30d0\u30a4\u30b9\u3068\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u7d71\u5408\u3059\u308b\u3053\u3068\u3067\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u306e\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001Apple\u306e\u30d8\u30eb\u30b9\u30b1\u30a2\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3068\u9023\u643a\u3059\u308b\u3053\u3068\u3067\u3001\u907a\u4f1d\u5b50\u30ea\u30b9\u30af\u306b\u5fdc\u3058\u305f\u5065\u5eb7\u30a2\u30c9\u30d0\u30a4\u30b9\u304c\u63d0\u4f9b\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u793e\u4f1a\u7684\u6d3b\u7528<\/strong><\/h3>\n\n\n\n<p>\u5c06\u6765\u7684\u306b\u306f\u3001\u5065\u5eb7\u4fdd\u967a\u3084\u516c\u8846\u885b\u751f\u30d7\u30ed\u30b0\u30e9\u30e0\u306b\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3082\u691c\u8a0e\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u7279\u5b9a\u306e\u75be\u60a3\u30ea\u30b9\u30af\u3092\u6301\u3064\u4eba\u306b\u5bfe\u3057\u3066\u4e88\u9632\u533b\u7642\u3092\u5f37\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u533b\u7642\u8cbb\u306e\u524a\u6e1b\u3084\u5065\u5eb7\u5bff\u547d\u306e\u5ef6\u4f38\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>16. \u907a\u4f1d\u5b50\u3068\u8178\u5185\u74b0\u5883\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u8178\u5185\u7d30\u83cc\u3068\u907a\u4f1d\u5b50\u306e\u76f8\u4e92\u4f5c\u7528\u304c\u5065\u5eb7\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u8178\u5185\u30d5\u30ed\u30fc\u30e9\uff08\u8178\u5185\u7d30\u83cc\u53e2\uff09\u306f\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u514d\u75ab\u6a5f\u80fd\u3084\u4ee3\u8b1d\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u8178\u5185\u7d30\u83cc\u306e\u69cb\u6210\u3068\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h3>\n\n\n\n<p>\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u8178\u5185\u7d30\u83cc\u306e\u7a2e\u985e\u3084\u30d0\u30e9\u30f3\u30b9\u306f\u907a\u4f1d\u7684\u8981\u56e0\u306b\u5f71\u97ff\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>LCT\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u3092\u6301\u3064\u4eba\u306f\u4e73\u7cd6\u3092\u5206\u89e3\u3067\u304d\u308b\u80fd\u529b\u304c\u9ad8\u304f\u3001\u4e73\u88fd\u54c1\u3092\u6d88\u5316\u3057\u3084\u3059\u3044\u8178\u5185\u74b0\u5883\u3092\u6301\u3064\u50be\u5411\u304c\u3042\u308a\u307e\u3059\uff08\u53c2\u8003\uff1aCell Host &amp; Microbe\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u8178\u5185\u7d30\u83cc\u3068\u514d\u75ab\u6a5f\u80fd<\/strong><\/h3>\n\n\n\n<p>\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u8178\u5185\u7d30\u83cc\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>NOD2\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u306f\u30af\u30ed\u30fc\u30f3\u75c5\uff08\u708e\u75c7\u6027\u8178\u75be\u60a3\uff09\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u8178\u5185\u30d5\u30ed\u30fc\u30e9\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u6804\u990a<\/strong><\/h3>\n\n\n\n<p>\u5c06\u6765\u7684\u306b\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3068\u8178\u5185\u7d30\u83cc\u306e\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u3057\u3001\u500b\u4eba\u306b\u6700\u9069\u306a\u98df\u4e8b\u30d7\u30e9\u30f3\u3092\u63d0\u6848\u3059\u308b\u30b5\u30fc\u30d3\u30b9\u304c\u666e\u53ca\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>\u77ed\u9396\u8102\u80aa\u9178\u3092\u5897\u3084\u3059\u767a\u9175\u98df\u54c1<\/strong>\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u4eba\u306e\u708e\u75c7\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>17. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/3881951_m-1024x683.jpg\" alt=\"\" class=\"wp-image-8421\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3881951_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3881951_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3881951_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3881951_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3881951_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306f\u904b\u52d5\u80fd\u529b\u3084\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u52b9\u679c\u306b\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u6301\u4e45\u529b\u3068\u77ac\u767a\u529b\u3092\u6c7a\u5b9a\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>ACTN3\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u306f\u3001\u7b4b\u8089\u306e\u53ce\u7e2e\u901f\u5ea6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u901f\u7b4b\u7dda\u7dad\u304c\u591a\u304f\u3001\u30b9\u30d7\u30ea\u30f3\u30c8\u3084\u91cd\u91cf\u6319\u3052\u306a\u3069\u306e\u30d1\u30ef\u30fc\u7cfb\u30b9\u30dd\u30fc\u30c4\u306b\u9069\u3057\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u6301\u4e45\u529b\u30b9\u30dd\u30fc\u30c4\u306b\u306f\u907a\u4f1d\u7684\u306b\u9069\u3057\u305f\u30bf\u30a4\u30d7\u304c\u5b58\u5728\u3057\u3001<strong>PPARGC1A\u907a\u4f1d\u5b50<\/strong>\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1aJournal of Applied Physiology\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u9178\u7d20\u4f9b\u7d66\u80fd\u529b\u3068\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9<\/strong><\/h3>\n\n\n\n<p>**EPO\u907a\u4f1d\u5b50\uff08\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\uff09**\u306f\u8d64\u8840\u7403\u306e\u751f\u6210\u3092\u8abf\u7bc0\u3057\u3001\u9178\u7d20\u306e\u904b\u642c\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u306b\u3088\u3063\u3066\u3001\u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u52b9\u679c\u3084\u6301\u4e45\u529b\u306e\u5411\u4e0a\u306b\u9055\u3044\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u602a\u6211\u306e\u30ea\u30b9\u30af\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30dd\u30fc\u30c4\u4e2d\u306e\u602a\u6211\u306e\u30ea\u30b9\u30af\u3082\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>COL5A1\u907a\u4f1d\u5b50\u306e\u5909\u7570<\/strong>\u306f\u3001\u976d\u5e2f\u306e\u67d4\u8edf\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u637b\u632b\u3084\u30a2\u30ad\u30ec\u30b9\u8171\u65ad\u88c2\u306e\u30ea\u30b9\u30af\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u57fa\u3065\u304d\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u602a\u6211\u4e88\u9632\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u958b\u767a\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>18. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u5275\u85ac\u306e\u9032\u5316<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u4eba\u3054\u3068\u306b\u6700\u9069\u306a\u85ac\u3092\u63d0\u4f9b\u3059\u308b\u300c\u7cbe\u5bc6\u533b\u7642\u300d\u304c\u9032\u5316\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u85ac\u5264\u306e\u4ee3\u8b1d\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u85ac\u306e\u52b9\u679c\u3084\u526f\u4f5c\u7528\u306e\u611f\u3058\u65b9\u306f\u907a\u4f1d\u7684\u8981\u56e0\u306b\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>CYP2D6\u907a\u4f1d\u5b50\u306e\u591a\u578b<\/strong>\u306f\u3001\u6297\u3046\u3064\u85ac\u3084\u93ae\u75db\u85ac\u306e\u4ee3\u8b1d\u901f\u5ea6\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u4eba\u306f\u3001\u85ac\u306e\u52b9\u679c\u304c\u5f37\u3059\u304e\u305f\u308a\u3001\u9006\u306b\u52b9\u304d\u306b\u304f\u304b\u3063\u305f\u308a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/tpj\/\">Pharmacogenomics Journal<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u304c\u3093\u6cbb\u7642\u306e\u500b\u5225\u5316<\/strong><\/h3>\n\n\n\n<p>\u304c\u3093\u6cbb\u7642\u3067\u306f\u3001<strong>EGFR\u907a\u4f1d\u5b50\u5909\u7570<\/strong>\u3092\u6301\u3064\u60a3\u8005\u306b\u5bfe\u3057\u3066\u3001\u7279\u5b9a\u306e\u5206\u5b50\u6a19\u7684\u85ac\u304c\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u6cbb\u7642\u6226\u7565\u3092\u7acb\u3066\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u5e0c\u5c11\u75be\u60a3\u3068\u907a\u4f1d\u5b50\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u6027\u75be\u60a3\u306e\u4e2d\u306b\u306f\u3001\u6709\u52b9\u306a\u6cbb\u7642\u6cd5\u304c\u9650\u3089\u308c\u3066\u3044\u308b\u3082\u306e\u304c\u591a\u3044\u3067\u3059\u304c\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001**\u810a\u9ac4\u6027\u7b4b\u840e\u7e2e\u75c7\uff08SMA\uff09**\u306e\u6cbb\u7642\u306b\u306f\u3001\u907a\u4f1d\u5b50\u88dc\u5145\u7642\u6cd5\u304c\u6210\u529f\u3057\u3066\u304a\u308a\u3001\u60a3\u8005\u306e\u4e88\u5f8c\u304c\u6539\u5584\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>19. \u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306e\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u3068\u502b\u7406\u7684\u8ab2\u984c<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u6d3b\u7528\u304c\u9032\u3080\u4e2d\u3067\u3001\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u306e\u4fdd\u8b77\u3084\u502b\u7406\u7684\u554f\u984c\u304c\u5927\u304d\u306a\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306e\u4fdd\u8b77<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306f\u500b\u4eba\u306e\u6700\u3082\u6a5f\u5bc6\u6027\u306e\u9ad8\u3044\u60c5\u5831\u306e\u4e00\u3064\u3067\u3042\u308a\u3001\u4e0d\u9069\u5207\u306a\u5229\u7528\u304c\u61f8\u5ff5\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u4fdd\u967a\u4f1a\u793e\u3084\u96c7\u7528\u4e3b\u304c\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u5229\u7528\u3057\u3066\u5dee\u5225\u3092\u884c\u3046\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u591a\u304f\u306e\u56fd\u3067\u306f\u907a\u4f1d\u5b50\u5dee\u5225\u3092\u9632\u3050\u6cd5\u5f8b\u304c\u5236\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.dnapolicy.org\/\">Genetics and Public Policy Center<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306e\u5546\u696d\u5229\u7528<\/strong><\/h3>\n\n\n\n<p>\u4e00\u90e8\u306e\u4f01\u696d\u306f\u3001\u6d88\u8cbb\u8005\u306e\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3092\u53ce\u96c6\u3057\u3001\u533b\u85ac\u54c1\u958b\u767a\u3084\u30de\u30fc\u30b1\u30c6\u30a3\u30f3\u30b0\u306b\u6d3b\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u6d88\u8cbb\u8005\u304c\u81ea\u8eab\u306e\u30c7\u30fc\u30bf\u306e\u5229\u7528\u306b\u3064\u3044\u3066\u5341\u5206\u306b\u7406\u89e3\u3057\u3066\u3044\u306a\u3044\u30b1\u30fc\u30b9\u3082\u3042\u308a\u3001\u900f\u660e\u6027\u306e\u5411\u4e0a\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u30b2\u30ce\u30e0\u7de8\u96c6\u3068\u502b\u7406<\/strong><\/h3>\n\n\n\n<p>CRISPR\u6280\u8853\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u30d2\u30c8\u306e\u907a\u4f1d\u5b50\u3092\u7de8\u96c6\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3057\u305f\u304c\u3001\u3053\u308c\u304c\u3069\u3053\u307e\u3067\u8a31\u5bb9\u3055\u308c\u308b\u3079\u304d\u304b\u3068\u3044\u3046\u8b70\u8ad6\u304c\u7d9a\u3044\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u300c\u30c7\u30b6\u30a4\u30ca\u30fc\u30d9\u30d3\u30fc\u300d\u306e\u554f\u984c\u3084\u3001\u751f\u6b96\u7d30\u80de\u306e\u7de8\u96c6\u306b\u95a2\u3059\u308b\u502b\u7406\u7684\u306a\u5236\u7d04\u304c\u91cd\u8981\u306a\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>20. \u907a\u4f1d\u5b50\u60c5\u5831\u306e\u672a\u6765\u3068\u793e\u4f1a\u3078\u306e\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/31570890_m-1024x683.jpg\" alt=\"\" class=\"wp-image-2387\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31570890_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31570890_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31570890_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31570890_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31570890_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u6d3b\u7528\u304c\u5e83\u304c\u308b\u3053\u3068\u3067\u3001\u793e\u4f1a\u5168\u4f53\u306e\u5065\u5eb7\u7ba1\u7406\u306e\u3042\u308a\u65b9\u3082\u5909\u5316\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u4e88\u9632\u533b\u7642\u306e\u767a\u5c55<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u4e88\u9632\u533b\u7642\u304c\u666e\u53ca\u3059\u308c\u3070\u3001\u75c5\u6c17\u306e\u65e9\u671f\u767a\u898b\u3084\u30ea\u30b9\u30af\u4f4e\u6e1b\u304c\u53ef\u80fd\u306b\u306a\u308a\u3001\u533b\u7642\u8cbb\u306e\u524a\u6e1b\u306b\u3082\u8ca2\u732e\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u500b\u5225\u5316\u30d8\u30eb\u30b9\u30b1\u30a2\u306e\u666e\u53ca<\/strong><\/h3>\n\n\n\n<p>\u30a6\u30a7\u30a2\u30e9\u30d6\u30eb\u30c7\u30d0\u30a4\u30b9\u3084AI\u8a3a\u65ad\u6280\u8853\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u306e\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u308a\u3001\u500b\u3005\u306b\u6700\u9069\u5316\u3055\u308c\u305f\u5065\u5eb7\u7dad\u6301\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u63d0\u4f9b\u3055\u308c\u308b\u6642\u4ee3\u304c\u5230\u6765\u3057\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u793e\u4f1a\u7684\u53d7\u5bb9\u3068\u6559\u80b2\u306e\u91cd\u8981\u6027<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u6b63\u3057\u3044\u7406\u89e3\u3068\u9069\u5207\u306a\u5229\u7528\u306e\u305f\u3081\u306b\u306f\u3001\u6559\u80b2\u3068\u5553\u767a\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u5b66\u6821\u6559\u80b2\u3084\u533b\u7642\u6a5f\u95a2\u3067\u306e\u907a\u4f1d\u5b50\u30ea\u30c6\u30e9\u30b7\u30fc\u306e\u5411\u4e0a\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator 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class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>1. \u907a\u4f1d\u5b50\u3068\u75c5\u6c17\u306e\u95a2\u4fc2 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[&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":10173,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6],"tags":[52,40,41,59,36,49,34,45,55],"class_list":["post-10172","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-basicknowledge","tag-dna-test","tag-privacy","tag-personalized-medicine","tag-59","tag-gene-testing","tag-gene-analysis","tag-genetic-identification","tag-genetics","tag-genetic-diseases"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/10172","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/comments?post=10172"}],"version-history":[{"count":1,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/10172\/revisions"}],"predecessor-version":[{"id":10180,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/10172\/revisions\/10180"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media\/10173"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media?parent=10172"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/categories?post=10172"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/tags?post=10172"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}