{"id":10190,"date":"2025-03-17T08:29:43","date_gmt":"2025-03-17T08:29:43","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=10190"},"modified":"2025-03-17T08:29:44","modified_gmt":"2025-03-17T08:29:44","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e6%97%a5%e5%b8%b8%e7%bf%92%e6%85%a3%ef%bc%9a%e4%bd%93%e3%81%ab%e5%84%aa%e3%81%97%e3%81%84%e3%83%a9%e3%82%a4%e3%83%95%e3%82%b9%e3%82%bf%e3%82%a4%e3%83%ab%e3%81%ae","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e6%97%a5%e5%b8%b8%e7%bf%92%e6%85%a3%ef%bc%9a%e4%bd%93%e3%81%ab%e5%84%aa%e3%81%97%e3%81%84%e3%83%a9%e3%82%a4%e3%83%95%e3%82%b9%e3%82%bf%e3%82%a4%e3%83%ab%e3%81%ae\/","title":{"rendered":"\u907a\u4f1d\u5b50\u3068\u65e5\u5e38\u7fd2\u6163\uff1a\u4f53\u306b\u512a\u3057\u3044\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u63d0\u6848"},"content":{"rendered":"\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. 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class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u907a\u4f1d\u5b50\u3068\u98df\u7fd2\u6163\u306e\u95a2\u9023\u6027<\/strong><\/h2>\n\n\n\n<p>\u98df\u4e8b\u306f\u5065\u5eb7\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u8981\u56e0\u306e\u4e00\u3064\u3067\u3059\u304c\u3001\u305d\u306e\u52b9\u679c\u306f\u500b\u4eba\u306e\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u907a\u4f1d\u5b50\u3068\u6804\u990a\u306e\u4ee3\u8b1d\u80fd\u529b<\/strong><\/h3>\n\n\n\n<p>\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306f\u3001\u6804\u990a\u7d20\u306e\u4ee3\u8b1d\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>FABP2\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u306f\u8102\u80aa\u306e\u5438\u53ce\u52b9\u7387\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u5909\u7570\u578b\u3092\u6301\u3064\u4eba\u306f\u8102\u8cea\u4ee3\u8b1d\u304c\u4f4e\u4e0b\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002(\u53c2\u8003: Nutrients)<\/p>\n\n\n\n<p>\u307e\u305f\u3001<strong>LCT\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u306f\u4e73\u7cd6\u4e0d\u8010\u75c7\u306b\u95a2\u9023\u3057\u3001\u4e73\u88fd\u54c1\u3092\u6d88\u5316\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002\u65e5\u672c\u4eba\u306e\u591a\u304f\u306f\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3063\u3066\u304a\u308a\u3001\u725b\u4e73\u3092\u98f2\u3080\u3068\u6d88\u5316\u4e0d\u826f\u3092\u8d77\u3053\u3057\u3084\u3059\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u591a\u69d8\u306a\u98df\u4e8b\u3068\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9<\/strong><\/h3>\n\n\n\n<p>\u98df\u4e8b\u306f\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\uff08\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u8abf\u7bc0\uff09\u306b\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>\u8449\u9178\u3001\u30d3\u30bf\u30df\u30f3B12\u3001\u30aa\u30e1\u30ac3\u8102\u80aa\u9178<\/strong>\u306a\u3069\u306e\u6804\u990a\u7d20\u306f\u3001DNA\u30e1\u30c1\u30eb\u5316\u3092\u901a\u3058\u3066\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u3001\u5730\u4e2d\u6d77\u5f0f\u98df\u4e8b\uff08\u30aa\u30ea\u30fc\u30d6\u30aa\u30a4\u30eb\u3001\u30ca\u30c3\u30c4\u3001\u9b5a\u4ecb\u985e\u304c\u8c4a\u5bcc\u306a\u98df\u4e8b\uff09\u306f\u708e\u75c7\u3092\u6291\u5236\u3057\u3001\u5065\u5eb7\u9577\u5bff\u3092\u4fc3\u9032\u3059\u308b\u52b9\u679c\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u907a\u4f1d\u5b50\u3068\u904b\u52d5\u7fd2\u6163\u306e\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/3881852_m-1024x683.jpg\" alt=\"\u30de\u30e9\u30bd\u30f3\" class=\"wp-image-2975\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/3881852_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/3881852_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/3881852_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/3881852_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/3881852_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u904b\u52d5\u306f\u5065\u5eb7\u3092\u7dad\u6301\u3059\u308b\u4e0a\u3067\u91cd\u8981\u3067\u3059\u304c\u3001\u904b\u52d5\u306e\u52b9\u679c\u3082\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u7b4b\u529b\u30fb\u6301\u4e45\u529b\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u7b4b\u8089\u306e\u30bf\u30a4\u30d7\u306f\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u6c7a\u307e\u308a\u3001<strong>ACTN3\u907a\u4f1d\u5b50<\/strong>\u306f\u901f\u7b4b\uff08\u77ac\u767a\u529b\u306b\u95a2\u4e0e\uff09\u3068\u9045\u7b4b\uff08\u6301\u4e45\u529b\u306b\u95a2\u4e0e\uff09\u306e\u5272\u5408\u3092\u8abf\u7bc0\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>RR\u578b<\/strong>\uff1a\u901f\u7b4b\u7dda\u7dad\u304c\u591a\u304f\u3001\u30b9\u30d7\u30ea\u30f3\u30c8\u3084\u30a6\u30a7\u30a4\u30c8\u30ea\u30d5\u30c6\u30a3\u30f3\u30b0\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n\n\n\n<li><strong>XX\u578b<\/strong>\uff1a\u9045\u7b4b\u7dda\u7dad\u304c\u591a\u304f\u3001\u30de\u30e9\u30bd\u30f3\u3084\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u306a\u3069\u306e\u6301\u4e45\u7cfb\u30b9\u30dd\u30fc\u30c4\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u307e\u305f\u3001<strong>ACE\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u6301\u4e45\u529b\u306e\u9ad8\u3044\u578b\uff08II\u578b\uff09\u3068\u77ac\u767a\u529b\u306e\u9ad8\u3044\u578b\uff08DD\u578b\uff09\u304c\u5b58\u5728\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u904b\u52d5\u306e\u9069\u5fdc\u6027<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u904b\u52d5\u306e\u9069\u5fdc\u901f\u5ea6\u304c\u7570\u306a\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>PPARGC1A\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u306f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u5897\u52a0\u306b\u95a2\u4e0e\u3057\u3001\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u52b9\u679c\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u907a\u4f1d\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u6700\u9069\u306a\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u4f5c\u6210\u3057\u3001\u52b9\u7387\u7684\u306b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u52b9\u679c\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u3068\u907a\u4f1d\u5b50\u306e\u76f8\u4e92\u4f5c\u7528<\/strong><\/h2>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u3078\u306e\u53cd\u5fdc\u3082\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>COMT\u907a\u4f1d\u5b50<\/strong>\u306f\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u5206\u89e3\u901f\u5ea6\u3092\u8abf\u6574\u3057\u3001\u305d\u306e\u907a\u4f1d\u7684\u5909\u7570\u304c\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9ad8\u6d3b\u6027\u578b<\/strong>\uff1a\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u306e\u5206\u89e3\u304c\u65e9\u304f\u3001\u30d7\u30ec\u30c3\u30b7\u30e3\u30fc\u306b\u5f37\u3044\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u6d3b\u6027\u578b<\/strong>\uff1a\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u306e\u5206\u89e3\u304c\u9045\u304f\u3001\u7dca\u5f35\u3057\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u30b9\u30c8\u30ec\u30b9\u8efd\u6e1b\u306e\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb<\/strong><\/h3>\n\n\n\n<p>\u7791\u60f3\u3001\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u3001\u9069\u5ea6\u306a\u904b\u52d5\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u3092\u8abf\u6574\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u7279\u306b\u3001\u30e8\u30ac\u3084\u6df1\u547c\u5438\u306f\u3001\u526f\u4ea4\u611f\u795e\u7d4c\u3092\u6d3b\u6027\u5316\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u3092\u8efd\u6e1b\u3059\u308b\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u7761\u7720\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"576\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/22933283_m-1024x576.jpg\" alt=\"\u5bdd\u3066\u3044\u308b\u7537\u6027\u306e\u6a2a\u9854\" class=\"wp-image-3497\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22933283_m-1024x576.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22933283_m-300x169.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22933283_m-768x432.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22933283_m-1536x864.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22933283_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u7761\u7720\u306e\u8cea\u3084\u5fc5\u8981\u306a\u7761\u7720\u6642\u9593\u3082\u3001\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u7761\u7720\u30ea\u30ba\u30e0\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>PER3\u907a\u4f1d\u5b50<\/strong>\u306f\u6982\u65e5\u30ea\u30ba\u30e0\uff08\u4f53\u5185\u6642\u8a08\uff09\u3092\u8abf\u6574\u3057\u3001\u671d\u578b\u30fb\u591c\u578b\u306e\u50be\u5411\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9577\u578b\u5909\u7570<\/strong>\uff1a\u671d\u578b\u306e\u50be\u5411\u304c\u5f37\u304f\u3001\u65e9\u5bdd\u65e9\u8d77\u304d\u304c\u5f97\u610f\u3002<\/li>\n\n\n\n<li><strong>\u77ed\u578b\u5909\u7570<\/strong>\uff1a\u591c\u578b\u306e\u50be\u5411\u304c\u5f37\u304f\u3001\u9045\u5bdd\u9045\u8d77\u304d\u304c\u591a\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u7761\u7720\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u7fd2\u6163<\/strong><\/h3>\n\n\n\n<p>\u7761\u7720\u74b0\u5883\u3092\u6574\u3048\u3001\u9069\u5207\u306a\u5149\u74b0\u5883\u3092\u78ba\u4fdd\u3059\u308b\u3053\u3068\u3067\u3001\u907a\u4f1d\u7684\u306a\u7761\u7720\u50be\u5411\u3092\u88dc\u3046\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u7279\u306b\u3001\u5bdd\u308b\u524d\u306e\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306e\u5236\u9650\u3084\u3001\u4e00\u5b9a\u306e\u7761\u7720\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u74b0\u5883\u8981\u56e0\u3068\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306e\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<p>\u5927\u6c17\u6c5a\u67d3\u3084\u5316\u5b66\u7269\u8cea\u306a\u3069\u306e\u74b0\u5883\u8981\u56e0\u3082\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u55ab\u7159\u306fDNA\u30e1\u30c1\u30eb\u5316\u3092\u5909\u5316\u3055\u305b\u3001\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u9006\u306b\u3001\u6297\u9178\u5316\u7269\u8cea\u3092\u8c4a\u5bcc\u306b\u542b\u3080\u98df\u4e8b\u306f\u3001\u907a\u4f1d\u5b50\u306e\u640d\u50b7\u3092\u9632\u304e\u3001\u5065\u5eb7\u3092\u7dad\u6301\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u907a\u4f1d\u5b50\u691c\u67fb\u3068\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u5229\u7528\u3057\u305f\u500b\u5225\u5316\u533b\u7642\u3084\u5065\u5eb7\u7ba1\u7406\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u81ea\u5206\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u77e5\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u98df\u4e8b\u30fb\u904b\u52d5\u30fb\u751f\u6d3b\u7fd2\u6163\u3092\u9078\u629e\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u9069\u5207\u306a\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3092\u69cb\u7bc9\u3059\u308b\u3053\u3068\u3067\u3001\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u3092\u6700\u9069\u5316\u3057\u3001\u5065\u5eb7\u7684\u306a\u751f\u6d3b\u3092\u9001\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u514d\u75ab\u529b\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-1024x683.jpg\" alt=\"\" class=\"wp-image-9900\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3377385_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u514d\u75ab\u529b\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u75c5\u6c17\u3078\u306e\u62b5\u6297\u529b\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09HLA\u907a\u4f1d\u5b50\u3068\u514d\u75ab\u53cd\u5fdc<\/strong><\/h3>\n\n\n\n<p><strong>HLA\uff08\u30d2\u30c8\u767d\u8840\u7403\u6297\u539f\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u306e\u4e2d\u5fc3\u7684\u306a\u5f79\u5272\u3092\u62c5\u3044\u3001\u611f\u67d3\u75c7\u3084\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002(<a href=\"https:\/\/www.jimmunol.org\/\">\u53c2\u8003: Journal of Immunology<\/a>)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA-B27<\/strong>\uff1a\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3084\u5f37\u76f4\u6027\u810a\u690e\u708e\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3002<\/li>\n\n\n\n<li><strong>HLA-DR4<\/strong>\uff1a1\u578b\u7cd6\u5c3f\u75c5\u3084\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306e\u767a\u75c7\u7387\u306b\u95a2\u9023\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u81ea\u7136\u514d\u75ab\u3068\u74b0\u5883\u8981\u56e0<\/strong><\/h3>\n\n\n\n<p>**TLR\u907a\u4f1d\u5b50\uff08\u30c8\u30fc\u30eb\u69d8\u53d7\u5bb9\u4f53\uff09**\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u3084\u7d30\u83cc\u3078\u306e\u53cd\u5fdc\u3092\u6c7a\u5b9a\u3057\u3001\u611f\u67d3\u75c7\u306b\u5bfe\u3059\u308b\u514d\u75ab\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306e\u89b3\u70b9\u304b\u3089\u3001\u9069\u5ea6\u306a\u904b\u52d5\u3084\u767a\u9175\u98df\u54c1\u306e\u6442\u53d6\u304cHLA\u3084TLR\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u6700\u9069\u5316\u3057\u3001\u514d\u75ab\u529b\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u8178\u5185\u74b0\u5883\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u8178\u5185\u74b0\u5883\u306f\u514d\u75ab\u529b\u3084\u4ee3\u8b1d\u3001\u7cbe\u795e\u7684\u5065\u5eb7\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3001\u907a\u4f1d\u7684\u8981\u56e0\u3068\u5bc6\u63a5\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u8178\u5185\u30d5\u30ed\u30fc\u30e9\u306e\u907a\u4f1d\u7684\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>\u8178\u5185\u7d30\u83cc\u306e\u69cb\u6210\u306f\u3001\u90e8\u5206\u7684\u306b\u907a\u4f1d\u306b\u3088\u3063\u3066\u6c7a\u307e\u308a\u307e\u3059\u3002<strong>FUT2\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u306b\u3088\u308a\u3001\u8178\u5185\u7d30\u83cc\u306e\u7a2e\u985e\u3084\u30d0\u30e9\u30f3\u30b9\u304c\u7570\u306a\u308a\u307e\u3059\u3002(<a href=\"https:\/\/www.nature.com\/nmicrobiol\/\">\u53c2\u8003: Nature Microbiology<\/a>)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FUT2\u306e\u6d3b\u6027\u578b<\/strong>\uff1a\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\u304c\u591a\u304f\u3001\u8178\u5185\u74b0\u5883\u304c\u826f\u597d\u3002<\/li>\n\n\n\n<li><strong>FUT2\u306e\u975e\u6d3b\u6027\u578b<\/strong>\uff1a\u8178\u5185\u7d30\u83cc\u306e\u591a\u69d8\u6027\u304c\u4f4e\u304f\u3001\u6d88\u5316\u5668\u7cfb\u306e\u554f\u984c\u304c\u8d77\u3053\u308a\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u8178\u5185\u7d30\u83cc\u3068\u98df\u4e8b<\/strong><\/h3>\n\n\n\n<p>\u767a\u9175\u98df\u54c1\uff08\u30e8\u30fc\u30b0\u30eb\u30c8\u3001\u5473\u564c\u3001\u7d0d\u8c46\uff09\u306f\u8178\u5185\u7d30\u83cc\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u6539\u5584\u3057\u3001\u8178\u5185\u74b0\u5883\u3092\u826f\u597d\u306b\u4fdd\u3064\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u7279\u306b\u3001\u98df\u7269\u7e4a\u7dad\u304c\u8c4a\u5bcc\u306a\u98df\u4e8b\u3092\u6442\u308b\u3053\u3068\u3067\u3001\u77ed\u9396\u8102\u80aa\u9178\u306e\u751f\u6210\u304c\u4fc3\u9032\u3055\u308c\u3001\u8178\u306e\u5065\u5eb7\u304c\u7dad\u6301\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u4ee3\u8b1d\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/29959560_m-1024x585.jpg\" alt=\"\u30cf\u30f3\u30d0\u30fc\u30ac\u30fc\u3092\u98df\u3079\u308b\u7537\u6027\" class=\"wp-image-3139\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/29959560_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/29959560_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/29959560_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/29959560_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/29959560_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u4ee3\u8b1d\u901f\u5ea6\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u8102\u8cea\u4ee3\u8b1d\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>APOE\u907a\u4f1d\u5b50<\/strong>\u306f\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002(\u53c2\u8003: Circulation Research)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>APOE \u03b54\u578b<\/strong>\uff1a\u60aa\u7389\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u9ad8\u304f\u306a\u308a\u3084\u3059\u304f\u3001\u5fc3\u75be\u60a3\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3002<\/li>\n\n\n\n<li><strong>APOE \u03b52\u578b<\/strong>\uff1a\u8102\u8cea\u4ee3\u8b1d\u304c\u826f\u597d\u3067\u3001\u5065\u5eb7\u7684\u306a\u4f53\u8cea\u3092\u7dad\u6301\u3057\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u7cd6\u4ee3\u8b1d\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>TCF7L2\u907a\u4f1d\u5b50<\/strong>\u306f\u7cd6\u4ee3\u8b1d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u7cd6\u8cea\u5236\u9650\u304c\u52b9\u679c\u7684\u304b\u3069\u3046\u304b\u306f\u3001\u3053\u306e\u907a\u4f1d\u5b50\u578b\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9ad8\u30ea\u30b9\u30af\u578b<\/strong>\uff1a\u7cd6\u8cea\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u304f\u3001\u8840\u7cd6\u5024\u304c\u4e0a\u6607\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u30ea\u30b9\u30af\u578b<\/strong>\uff1a\u7cd6\u4ee3\u8b1d\u304c\u5b89\u5b9a\u3057\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u304c\u826f\u597d\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u4eba\u306f\u3001\u4f4eGI\uff08\u30b0\u30ea\u30bb\u30df\u30c3\u30af\u30fb\u30a4\u30f3\u30c7\u30c3\u30af\u30b9\uff09\u306e\u98df\u54c1\u3092\u4e2d\u5fc3\u306b\u6442\u53d6\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. \u30a2\u30eb\u30b3\u30fc\u30eb\u611f\u53d7\u6027\u3068\u907a\u4f1d\u5b50<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30eb\u30b3\u30fc\u30eb\u306e\u5206\u89e3\u80fd\u529b\u306f\u3001\u907a\u4f1d\u7684\u306b\u6c7a\u307e\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09ALDH2\u907a\u4f1d\u5b50\u3068\u30a2\u30eb\u30b3\u30fc\u30eb\u8010\u6027<\/strong><\/h3>\n\n\n\n<p><strong>ALDH2\uff08\u30a2\u30eb\u30c7\u30d2\u30c9\u8131\u6c34\u7d20\u9175\u7d202\uff09\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u306f\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u306e\u4ee3\u8b1d\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002(<a href=\"https:\/\/www.nature.com\/jhg\/\">\u53c2\u8003: Journal of Human Genetics<\/a>)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6d3b\u6027\u578b\uff08GG\u578b\uff09<\/strong>\uff1a\u30a2\u30eb\u30b3\u30fc\u30eb\u3092\u52b9\u7387\u7684\u306b\u5206\u89e3\u3067\u304d\u308b\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u6d3b\u6027\u578b\uff08GA\u578b\uff09<\/strong>\uff1a\u30a2\u30eb\u30b3\u30fc\u30eb\u5206\u89e3\u304c\u9045\u304f\u3001\u9854\u304c\u8d64\u304f\u306a\u308a\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>\u975e\u6d3b\u6027\u578b\uff08AA\u578b\uff09<\/strong>\uff1a\u30a2\u30eb\u30b3\u30fc\u30eb\u5206\u89e3\u304c\u307b\u3068\u3093\u3069\u3067\u304d\u305a\u3001\u98f2\u9152\u306b\u9069\u3055\u306a\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u98f2\u9152\u7fd2\u6163\u306e\u8abf\u6574<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u7684\u306b\u30a2\u30eb\u30b3\u30fc\u30eb\u5206\u89e3\u80fd\u529b\u304c\u4f4e\u3044\u4eba\u306f\u3001\u98f2\u9152\u91cf\u3092\u5236\u9650\u3057\u3001\u809d\u81d3\u3078\u306e\u8ca0\u62c5\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u98f2\u9152\u306b\u3088\u308b\u8840\u5727\u4e0a\u6607\u306e\u30ea\u30b9\u30af\u3082\u907a\u4f1d\u7684\u8981\u56e0\u3067\u7570\u306a\u308b\u305f\u3081\u3001\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>12. \u30ab\u30d5\u30a7\u30a4\u30f3\u611f\u53d7\u6027\u3068\u907a\u4f1d\u5b50<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"684\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31585177_m-1024x684.jpg\" alt=\"\" class=\"wp-image-10198\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31585177_m-1024x684.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31585177_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31585177_m-768x513.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31585177_m-1536x1026.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31585177_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u4ee3\u8b1d\u80fd\u529b\u3082\u3001\u907a\u4f1d\u7684\u306b\u6c7a\u307e\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09CYP1A2\u907a\u4f1d\u5b50\u3068\u30ab\u30d5\u30a7\u30a4\u30f3\u4ee3\u8b1d<\/strong><\/h3>\n\n\n\n<p><strong>CYP1A2\u907a\u4f1d\u5b50<\/strong>\u306f\u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u5206\u89e3\u901f\u5ea6\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002(\u53c2\u8003: American Journal of Clinical Nutrition)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u901f\u3044\u4ee3\u8b1d\u578b\uff08AA\u578b\uff09<\/strong>\uff1a\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u3059\u3050\u306b\u5206\u89e3\u3057\u3001\u5f71\u97ff\u304c\u5c11\u306a\u3044\u3002<\/li>\n\n\n\n<li><strong>\u9045\u3044\u4ee3\u8b1d\u578b\uff08CC\u578b\uff09<\/strong>\uff1a\u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u5206\u89e3\u304c\u9045\u304f\u3001\u4e0d\u7720\u3084\u5fc3\u62cd\u6570\u306e\u5897\u52a0\u3092\u5f15\u304d\u8d77\u3053\u3057\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u9069\u5207\u306a\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6<\/strong><\/h3>\n\n\n\n<p>\u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u4eba\u306f\u3001\u5915\u65b9\u4ee5\u964d\u306e\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6\u3092\u63a7\u3048\u3001\u7761\u7720\u306e\u8cea\u3092\u78ba\u4fdd\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>13. \u808c\u306e\u5065\u5eb7\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u76ae\u819a\u306e\u8001\u5316\u3084\u7d2b\u5916\u7dda\u3078\u306e\u8010\u6027\u3082\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09COL1A1\u907a\u4f1d\u5b50\u3068\u808c\u306e\u5f3e\u529b<\/strong><\/h3>\n\n\n\n<p><strong>COL1A1\u907a\u4f1d\u5b50<\/strong>\u306f\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u751f\u6210\u306b\u95a2\u4e0e\u3057\u3001\u808c\u306e\u5f3e\u529b\u3084\u30b7\u30ef\u306e\u767a\u751f\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9ad8\u767a\u73fe\u578b<\/strong>\uff1a\u808c\u306e\u5f3e\u529b\u304c\u9ad8\u304f\u3001\u8001\u5316\u304c\u9045\u3044\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u767a\u73fe\u578b<\/strong>\uff1a\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u751f\u6210\u304c\u5c11\u306a\u304f\u3001\u30b7\u30ef\u3084\u305f\u308b\u307f\u304c\u51fa\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u7d2b\u5916\u7dda\u8010\u6027\u3068MC1R\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p><strong>MC1R\u907a\u4f1d\u5b50<\/strong>\u306f\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u3092\u8abf\u6574\u3057\u3001\u7d2b\u5916\u7dda\u3078\u306e\u8010\u6027\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6d3b\u6027\u578b<\/strong>\uff1a\u30e1\u30e9\u30cb\u30f3\u304c\u591a\u304f\u3001\u7d2b\u5916\u7dda\u304b\u3089\u808c\u3092\u4fdd\u8b77\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>\u975e\u6d3b\u6027\u578b<\/strong>\uff1a\u7d2b\u5916\u7dda\u306b\u5f31\u304f\u3001\u30b7\u30df\u3084\u305d\u3070\u304b\u3059\u304c\u3067\u304d\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u7d2b\u5916\u7dda\u306b\u5f31\u3044\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u4eba\u306f\u3001\u65e5\u713c\u3051\u6b62\u3081\u306e\u4f7f\u7528\u3084\u6297\u9178\u5316\u98df\u54c1\u306e\u6442\u53d6\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>14. \u9aa8\u5bc6\u5ea6\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u9aa8\u5bc6\u5ea6\u306f\u5e74\u9f62\u3068\u3068\u3082\u306b\u5909\u5316\u3057\u307e\u3059\u304c\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u305d\u306e\u5909\u5316\u306e\u901f\u5ea6\u3084\u9aa8\u6298\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09VDR\u907a\u4f1d\u5b50\u3068\u30ab\u30eb\u30b7\u30a6\u30e0\u5438\u53ce<\/strong><\/h3>\n\n\n\n<p><strong>VDR\uff08\u30d3\u30bf\u30df\u30f3D\u53d7\u5bb9\u4f53\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u306e\u5438\u53ce\u3068\u9aa8\u5f62\u6210\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/onlinelibrary.wiley.com\/journal\/15234681\">\u53c2\u8003: Journal of Bone and Mineral Research<\/a>)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9ad8\u767a\u73fe\u578b<\/strong>\uff1a\u30ab\u30eb\u30b7\u30a6\u30e0\u5438\u53ce\u304c\u826f\u597d\u3067\u3001\u9aa8\u5bc6\u5ea6\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u767a\u73fe\u578b<\/strong>\uff1a\u30ab\u30eb\u30b7\u30a6\u30e0\u5438\u53ce\u304c\u60aa\u304f\u3001\u9aa8\u7c97\u9b06\u75c7\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u9aa8\u5bc6\u5ea6\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306e\u751f\u6d3b\u7fd2\u6163<\/strong><\/h3>\n\n\n\n<p>VDR\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u8003\u616e\u3057\u3001\u4ee5\u4e0b\u306e\u7fd2\u6163\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d3\u30bf\u30df\u30f3D\u306e\u9069\u5207\u306a\u6442\u53d6<\/strong>\uff08\u9b5a\u3001\u5375\u3001\u65e5\u5149\u6d74\uff09<\/li>\n\n\n\n<li><strong>\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u8c4a\u5bcc\u306a\u98df\u54c1\u306e\u6442\u53d6<\/strong>\uff08\u4e73\u88fd\u54c1\u3001\u5c0f\u9b5a\u3001\u8c46\u8150\uff09<\/li>\n\n\n\n<li><strong>\u9069\u5ea6\u306a\u8ca0\u8377\u3092\u304b\u3051\u308b\u904b\u52d5<\/strong>\uff08\u30a6\u30a9\u30fc\u30ad\u30f3\u30b0\u3001\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u7279\u306b\u3001\u904b\u52d5\u306f\u9aa8\u5bc6\u5ea6\u306e\u7dad\u6301\u306b\u52b9\u679c\u7684\u3067\u3042\u308a\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u3092\u88dc\u3046\u91cd\u8981\u306a\u624b\u6bb5\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>15. \u8840\u5727\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/32093911_m-1024x683.jpg\" alt=\"\" class=\"wp-image-10040\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32093911_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32093911_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32093911_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32093911_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32093911_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8840\u5727\u306f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u30ea\u30b9\u30af\u306b\u76f4\u63a5\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u8981\u56e0\u3067\u3042\u308a\u3001\u907a\u4f1d\u7684\u8981\u7d20\u3068\u751f\u6d3b\u7fd2\u6163\u304c\u5927\u304d\u304f\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09ACE\u907a\u4f1d\u5b50\u3068\u8840\u5727\u8abf\u6574<\/strong><\/h3>\n\n\n\n<p><strong>ACE\uff08\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u8840\u7ba1\u306e\u53ce\u7e2e\u3068\u8840\u5727\u8abf\u6574\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002(\u53c2\u8003: Hypertension Journal)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>DD\u578b<\/strong>\uff1a\u8840\u5727\u304c\u4e0a\u6607\u3057\u3084\u3059\u304f\u3001\u9ad8\u8840\u5727\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>II\u578b<\/strong>\uff1a\u8840\u7ba1\u304c\u62e1\u5f35\u3057\u3084\u3059\u304f\u3001\u4f4e\u8840\u5727\u50be\u5411\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u9ad8\u8840\u5727\u3092\u9632\u3050\u305f\u3081\u306e\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb<\/strong><\/h3>\n\n\n\n<p>ACE\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u53d7\u3051\u308b\u4eba\u306f\u3001\u4ee5\u4e0b\u306e\u751f\u6d3b\u7fd2\u6163\u3092\u610f\u8b58\u3059\u308b\u3068\u826f\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5869\u5206\u6442\u53d6\u3092\u6291\u3048\u308b<\/strong>\uff08\u7279\u306bDD\u578b\u306e\u4eba\uff09<\/li>\n\n\n\n<li><strong>\u30ab\u30ea\u30a6\u30e0\u3092\u591a\u304f\u542b\u3080\u98df\u54c1\u3092\u6442\u308b<\/strong>\uff08\u30d0\u30ca\u30ca\u3001\u30a2\u30dc\u30ab\u30c9\u3001\u307b\u3046\u308c\u3093\u8349\uff09<\/li>\n\n\n\n<li><strong>\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u3092\u5fb9\u5e95\u3059\u308b<\/strong>\uff08\u8840\u5727\u4e0a\u6607\u3092\u9632\u3050\u305f\u3081\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u904b\u52d5\u3084\u6e1b\u5869\u98df\u306e\u5c0e\u5165\u306b\u3088\u308a\u3001\u907a\u4f1d\u7684\u306a\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>16. \u8102\u8cea\u7570\u5e38\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u8840\u4e2d\u306e\u8102\u8cea\u30ec\u30d9\u30eb\uff08\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3084\u4e2d\u6027\u8102\u80aa\uff09\u306f\u3001\u907a\u4f1d\u5b50\u3068\u751f\u6d3b\u7fd2\u6163\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u6c7a\u307e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09APOA5\u907a\u4f1d\u5b50\u3068\u8102\u8cea\u4ee3\u8b1d<\/strong><\/h3>\n\n\n\n<p><strong>APOA5\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u4e2d\u6027\u8102\u80aa\u306e\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057\u3001\u305d\u306e\u5909\u7570\u304c\u8102\u8cea\u7570\u5e38\u306e\u30ea\u30b9\u30af\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002(\u53c2\u8003: Lipids in Health and Disease)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5909\u7570\u578b\u3092\u6301\u3064\u4eba<\/strong>\uff1a\u4e2d\u6027\u8102\u80aa\u306e\u84c4\u7a4d\u304c\u8d77\u3053\u308a\u3084\u3059\u304f\u3001\u52d5\u8108\u786c\u5316\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>\u901a\u5e38\u578b\u306e\u4eba<\/strong>\uff1a\u8102\u8cea\u4ee3\u8b1d\u304c\u826f\u597d\u3067\u3001\u5065\u5eb7\u7684\u306a\u8102\u8cea\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u7dad\u6301\u3057\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u8102\u8cea\u7570\u5e38\u3092\u9632\u3050\u305f\u3081\u306e\u98df\u7fd2\u6163<\/strong><\/h3>\n\n\n\n<p>APOA5\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u4eba\u306f\u3001\u4ee5\u4e0b\u306e\u5bfe\u7b56\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3092\u6442\u53d6<\/strong>\uff08\u9752\u9b5a\u3001\u304f\u308b\u307f\u3001\u4e9c\u9ebb\u4ec1\u6cb9\uff09<\/li>\n\n\n\n<li><strong>\u30c8\u30e9\u30f3\u30b9\u8102\u80aa\u9178\u3092\u907f\u3051\u308b<\/strong>\uff08\u52a0\u5de5\u98df\u54c1\u3001\u30de\u30fc\u30ac\u30ea\u30f3\uff09<\/li>\n\n\n\n<li><strong>\u9069\u5ea6\u306a\u904b\u52d5\u3092\u53d6\u308a\u5165\u308c\u308b<\/strong>\uff08\u8102\u8cea\u4ee3\u8b1d\u3092\u6d3b\u6027\u5316\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u8102\u8cea\u7570\u5e38\u3092\u4e88\u9632\u3059\u308b\u3053\u3068\u3067\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u5927\u5e45\u306b\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>17. \u30ab\u30ed\u30ea\u30fc\u5236\u9650\u3068\u5bff\u547d\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u304c\u5bff\u547d\u3092\u5ef6\u3070\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u3001\u591a\u304f\u306e\u7814\u7a76\u3067\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09SIRT1\u907a\u4f1d\u5b50\u3068\u9577\u5bff<\/strong><\/h3>\n\n\n\n<p><strong>SIRT1\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u8001\u5316\u306e\u6291\u5236\u3084\u7d30\u80de\u306e\u4fee\u5fa9\u306b\u95a2\u4e0e\u3057\u3001\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u306b\u3088\u3063\u3066\u305d\u306e\u50cd\u304d\u304c\u6d3b\u6027\u5316\u3057\u307e\u3059\u3002(<a href=\"https:\/\/onlinelibrary.wiley.com\/journal\/14749726\">\u53c2\u8003: Aging Cell<\/a>)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>SIRT1\u306e\u9ad8\u767a\u73fe\u578b<\/strong>\uff1a\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u304f\u3001\u8001\u5316\u3092\u9045\u3089\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>SIRT1\u306e\u4f4e\u767a\u73fe\u578b<\/strong>\uff1a\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u306e\u52b9\u679c\u304c\u9650\u5b9a\u7684\u306a\u5834\u5408\u304c\u3042\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u9069\u5207\u306a\u30ab\u30ed\u30ea\u30fc\u6442\u53d6\u3068\u5065\u5eb7\u7dad\u6301<\/strong><\/h3>\n\n\n\n<p>\u5bff\u547d\u3092\u5ef6\u3070\u3059\u305f\u3081\u306b\u306f\u3001\u6975\u7aef\u306a\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u3067\u306f\u306a\u304f\u3001\u4ee5\u4e0b\u306e\u65b9\u6cd5\u304c\u6709\u52b9\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u98df\u4e8b\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b<\/strong>\uff08\u52a0\u5de5\u98df\u54c1\u3092\u907f\u3051\u308b\uff09<\/li>\n\n\n\n<li><strong>\u6642\u9593\u5236\u9650\u98df\uff0816:8\u98df\u4e8b\u6cd5\uff09\u3092\u5b9f\u8df5\u3059\u308b<\/strong><\/li>\n\n\n\n<li><strong>\u6297\u9178\u5316\u7269\u8cea\u3092\u591a\u304f\u6442\u308b<\/strong>\uff08\u91ce\u83dc\u3001\u679c\u7269\u3001\u7dd1\u8336\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u9069\u5207\u306a\u98df\u7fd2\u6163\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u3067\u3001\u907a\u4f1d\u7684\u8981\u56e0\u306b\u95a2\u4fc2\u306a\u304f\u5065\u5eb7\u5bff\u547d\u3092\u5ef6\u3070\u3059\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>18. \u74b0\u5883\u6bd2\u7d20\u3068\u907a\u4f1d\u5b50\u306e\u76f8\u4e92\u4f5c\u7528<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/31350013_m-1024x585.jpg\" alt=\"\" class=\"wp-image-1773\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31350013_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31350013_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31350013_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31350013_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31350013_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u74b0\u5883\u8981\u56e0\u3082\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u5065\u5eb7\u30ea\u30b9\u30af\u3092\u5897\u52a0\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09GST\u907a\u4f1d\u5b50\u3068\u89e3\u6bd2\u80fd\u529b<\/strong><\/h3>\n\n\n\n<p><strong>GST\uff08\u30b0\u30eb\u30bf\u30c1\u30aa\u30f3S\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u4f53\u5185\u306e\u6bd2\u7d20\u3092\u89e3\u6bd2\u3059\u308b\u9175\u7d20\u3092\u8abf\u7bc0\u3057\u307e\u3059\u3002(<a href=\"https:\/\/ehp.niehs.nih.gov\/\">\u53c2\u8003: Environmental Health Perspectives<\/a>)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>GST\u306e\u6d3b\u6027\u578b<\/strong>\uff1a\u6709\u5bb3\u7269\u8cea\u306e\u6392\u51fa\u80fd\u529b\u304c\u9ad8\u304f\u3001\u74b0\u5883\u6bd2\u7d20\u306e\u5f71\u97ff\u3092\u53d7\u3051\u306b\u304f\u3044\u3002<\/li>\n\n\n\n<li><strong>GST\u306e\u4f4e\u6d3b\u6027\u578b<\/strong>\uff1a\u6709\u5bb3\u7269\u8cea\u306e\u84c4\u7a4d\u304c\u8d77\u3053\u308a\u3084\u3059\u304f\u3001\u767a\u304c\u3093\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u74b0\u5883\u6bd2\u7d20\u3092\u907f\u3051\u308b\u751f\u6d3b\u7fd2\u6163<\/strong><\/h3>\n\n\n\n<p>GST\u907a\u4f1d\u5b50\u306e\u4f4e\u6d3b\u6027\u578b\u306e\u4eba\u306f\u3001\u4ee5\u4e0b\u306e\u5bfe\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u3067\u5065\u5eb7\u3092\u5b88\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30aa\u30fc\u30ac\u30cb\u30c3\u30af\u98df\u54c1\u3092\u9078\u3076<\/strong>\uff08\u8fb2\u85ac\u306e\u5f71\u97ff\u3092\u907f\u3051\u308b\uff09<\/li>\n\n\n\n<li><strong>\u5316\u5b66\u7269\u8cea\u3092\u542b\u3080\u88fd\u54c1\u3092\u6e1b\u3089\u3059<\/strong>\uff08\u30d7\u30e9\u30b9\u30c1\u30c3\u30af\u88fd\u54c1\u3001\u5316\u7ca7\u54c1\uff09<\/li>\n\n\n\n<li><strong>\u30c7\u30c8\u30c3\u30af\u30b9\u52b9\u679c\u306e\u3042\u308b\u98df\u54c1\u3092\u6442\u308b<\/strong>\uff08\u30d6\u30ed\u30c3\u30b3\u30ea\u30fc\u3001\u306b\u3093\u306b\u304f\u3001\u7dd1\u8336\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u5bfe\u7b56\u306b\u3088\u308a\u3001\u74b0\u5883\u6bd2\u7d20\u306e\u5f71\u97ff\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>19. \u904b\u52d5\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u306e\u52b9\u679c\u3084\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306e\u5411\u4e0a\u306b\u306f\u3001\u907a\u4f1d\u5b50\u304c\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09ACTN3\u907a\u4f1d\u5b50\u3068\u7b4b\u7dda\u7dad\u306e\u30bf\u30a4\u30d7<\/strong><\/h3>\n\n\n\n<p><strong>ACTN3\u907a\u4f1d\u5b50<\/strong>\u306f\u901f\u7b4b\u7dda\u7dad\uff08\u30bf\u30a4\u30d7II\uff09\u306e\u767a\u9054\u306b\u95a2\u4e0e\u3057\u3001\u904b\u52d5\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002(\u53c2\u8003: Journal of Applied Physiology)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>RR\u578b<\/strong>\uff1a\u901f\u7b4b\u7dda\u7dad\u304c\u591a\u304f\u3001\u30b9\u30d7\u30ea\u30f3\u30c8\u3084\u91cd\u91cf\u6319\u3052\u306b\u5411\u3044\u3066\u3044\u308b\u3002<\/li>\n\n\n\n<li><strong>RX\u578b<\/strong>\uff1a\u901f\u7b4b\u3068\u9045\u7b4b\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u826f\u304f\u3001\u591a\u304f\u306e\u30b9\u30dd\u30fc\u30c4\u306b\u9069\u5fdc\u53ef\u80fd\u3002<\/li>\n\n\n\n<li><strong>XX\u578b<\/strong>\uff1a\u9045\u7b4b\u7dda\u7dad\u304c\u591a\u304f\u3001\u6301\u4e45\u529b\u7cfb\u30b9\u30dd\u30fc\u30c4\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3001\u500b\u4eba\u306b\u9069\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u904b\u52d5\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3068\u6301\u4e45\u529b\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u529b\u306e\u5411\u4e0a\u306b\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u52b9\u7387\u304c\u91cd\u8981\u3067\u3059\u3002<strong>PPARGC1A\u907a\u4f1d\u5b50<\/strong>\u306f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u751f\u6210\u3092\u8abf\u7bc0\u3057\u3001\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u52b9\u679c\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9ad8\u767a\u73fe\u578b<\/strong>\uff1a\u6709\u9178\u7d20\u904b\u52d5\u306e\u9069\u5fdc\u304c\u826f\u304f\u3001\u6301\u4e45\u529b\u5411\u4e0a\u304c\u671f\u5f85\u3067\u304d\u308b\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u767a\u73fe\u578b<\/strong>\uff1a\u6301\u4e45\u529b\u304c\u3064\u304d\u306b\u304f\u304f\u3001\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u5fc5\u8981\u3002<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>20. \u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u5fc3\u306e\u5065\u5eb7\u3082\u907a\u4f1d\u7684\u8981\u56e0\u3068\u5bc6\u63a5\u306b\u95a2\u4fc2\u3057\u3066\u304a\u308a\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3084\u6c17\u5206\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u30bb\u30ed\u30c8\u30cb\u30f3\u8f38\u9001\u4f53\u907a\u4f1d\u5b50\uff08SLC6A4\uff09<\/strong><\/h3>\n\n\n\n<p><strong>SLC6A4\u907a\u4f1d\u5b50<\/strong>\u306f\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u53d6\u308a\u8fbc\u307f\u3092\u8abf\u6574\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u3084\u3046\u3064\u75c5\u306e\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002(\u53c2\u8003: JAMA Psychiatry)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>L\u578b\uff08\u9577\u578b\uff09<\/strong>\uff1a\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u53d6\u308a\u8fbc\u307f\u304c\u826f\u304f\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>S\u578b\uff08\u77ed\u578b\uff09<\/strong>\uff1a\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u53d6\u308a\u8fbc\u307f\u304c\u4f4e\u304f\u3001\u30b9\u30c8\u30ec\u30b9\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09BDNF\u907a\u4f1d\u5b50\u3068\u8133\u306e\u5065\u5eb7<\/strong><\/h3>\n\n\n\n<p><strong>BDNF\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u795e\u7d4c\u7d30\u80de\u306e\u6210\u9577\u3068\u4fee\u5fa9\u306b\u95a2\u4e0e\u3057\u3001\u8a8d\u77e5\u6a5f\u80fd\u3084\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002(<a href=\"https:\/\/www.nature.com\/neuro\/\">\u53c2\u8003: Nature Neuroscience<\/a>)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9ad8\u767a\u73fe\u578b<\/strong>\uff1a\u30b9\u30c8\u30ec\u30b9\u306b\u5f37\u304f\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u9632\u3050\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u767a\u73fe\u578b<\/strong>\uff1a\u30b9\u30c8\u30ec\u30b9\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u304f\u3001\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306e\u554f\u984c\u304c\u751f\u3058\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u904b\u52d5\u3084\u7791\u60f3\u3001\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u306e\u6442\u53d6\u306f\u3001BDNF\u306e\u767a\u73fe\u3092\u5897\u52a0\u3055\u305b\u308b\u305f\u3081\u3001\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u5411\u4e0a\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>21. \u76ae\u819a\u8001\u5316\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/30465243_m-1024x683.jpg\" alt=\"\u7f8e\u9854\u30ed\u30fc\u30e9\u30fc\u3092\u982c\u306b\u4f7f\u3046\u30b7\u30cb\u30a2\u5973\u6027\" class=\"wp-image-3335\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30465243_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30465243_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30465243_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30465243_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30465243_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u76ae\u819a\u306e\u5065\u5eb7\u3084\u8001\u5316\u306e\u9032\u884c\u901f\u5ea6\u3082\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u30b3\u30e9\u30fc\u30b2\u30f3\u3068\u808c\u306e\u5f3e\u529b<\/strong><\/h3>\n\n\n\n<p><strong>COL1A1\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u751f\u6210\u306b\u95a2\u4e0e\u3057\u3001\u808c\u306e\u5f3e\u529b\u3084\u30b7\u30ef\u306e\u767a\u751f\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002(<a href=\"https:\/\/www.jdsjournal.com\/\">\u53c2\u8003: Journal of Dermatological Science<\/a>)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9ad8\u767a\u73fe\u578b<\/strong>\uff1a\u30b3\u30e9\u30fc\u30b2\u30f3\u751f\u6210\u304c\u6d3b\u767a\u3067\u3001\u808c\u306e\u5f3e\u529b\u304c\u7dad\u6301\u3055\u308c\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u767a\u73fe\u578b<\/strong>\uff1a\u30b3\u30e9\u30fc\u30b2\u30f3\u304c\u6e1b\u5c11\u3057\u3084\u3059\u304f\u3001\u30b7\u30ef\u304c\u3067\u304d\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u7d2b\u5916\u7dda\u3078\u306e\u8010\u6027<\/strong><\/h3>\n\n\n\n<p><strong>MC1R\u907a\u4f1d\u5b50<\/strong>\u306f\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u3092\u8abf\u7bc0\u3057\u3001\u7d2b\u5916\u7dda\u3078\u306e\u8010\u6027\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9ad8\u767a\u73fe\u578b<\/strong>\uff1a\u7d2b\u5916\u7dda\u306b\u5f37\u304f\u3001\u808c\u30c0\u30e1\u30fc\u30b8\u304c\u5c11\u306a\u3044\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u767a\u73fe\u578b<\/strong>\uff1a\u7d2b\u5916\u7dda\u306b\u5f31\u304f\u3001\u30b7\u30df\u3084\u305d\u3070\u304b\u3059\u304c\u3067\u304d\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u30d3\u30bf\u30df\u30f3C\u3084E\u306e\u6442\u53d6\u3001\u9069\u5207\u306a\u7d2b\u5916\u7dda\u5bfe\u7b56\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u808c\u306e\u5065\u5eb7\u3092\u5b88\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>22. \u7761\u7720\u306e\u8cea\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u7761\u7720\u306e\u8cea\u3084\u7761\u7720\u30ea\u30ba\u30e0\u3082\u3001\u907a\u4f1d\u7684\u8981\u56e0\u306b\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09PER3\u907a\u4f1d\u5b50\u3068\u6982\u65e5\u30ea\u30ba\u30e0<\/strong><\/h3>\n\n\n\n<p><strong>PER3\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u4f53\u5185\u6642\u8a08\u3092\u8abf\u6574\u3057\u3001\u671d\u578b\u30fb\u591c\u578b\u306e\u50be\u5411\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002(\u53c2\u8003: Sleep Journal)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9577\u578b\u5909\u7570<\/strong>\uff1a\u671d\u578b\u3067\u3001\u65e9\u5bdd\u65e9\u8d77\u304d\u304c\u5f97\u610f\u3002<\/li>\n\n\n\n<li><strong>\u77ed\u578b\u5909\u7570<\/strong>\uff1a\u591c\u578b\u3067\u3001\u591c\u66f4\u304b\u3057\u3057\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u7761\u7720\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u65b9\u6cd5<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9069\u5207\u306a\u5149\u74b0\u5883\u3092\u6574\u3048\u308b<\/strong>\uff08\u671d\u65e5\u3092\u6d74\u3073\u3001\u591c\u306f\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3092\u907f\u3051\u308b\uff09<\/li>\n\n\n\n<li><strong>\u30e1\u30e9\u30c8\u30cb\u30f3\u5206\u6ccc\u3092\u4fc3\u3059\u98df\u54c1\u3092\u6442\u53d6<\/strong>\uff08\u30d0\u30ca\u30ca\u3001\u30ca\u30c3\u30c4\u3001\u4e73\u88fd\u54c1\uff09<\/li>\n\n\n\n<li><strong>\u5bdd\u308b\u524d\u306e\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6\u3092\u63a7\u3048\u308b<\/strong>\uff08CYP1A2\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u53d7\u3051\u308b\uff09<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>23. \u5065\u5eb7\u5bff\u547d\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306f\u5bff\u547d\u3060\u3051\u3067\u306a\u304f\u3001\u5065\u5eb7\u7684\u306b\u751f\u304d\u308b\u305f\u3081\u306e\u8981\u56e0\u306b\u3082\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09FOXO3\u907a\u4f1d\u5b50\u3068\u9577\u5bff<\/strong><\/h3>\n\n\n\n<p><strong>FOXO3\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u7d30\u80de\u306e\u8001\u5316\u3092\u9632\u304e\u3001\u9577\u5bff\u306b\u95a2\u4e0e\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002(<a href=\"https:\/\/onlinelibrary.wiley.com\/journal\/14749726\">\u53c2\u8003: Aging Cell<\/a>)<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9ad8\u767a\u73fe\u578b<\/strong>\uff1a\u6297\u9178\u5316\u80fd\u529b\u304c\u9ad8\u304f\u3001\u8001\u5316\u304c\u9045\u3044\u3002<\/li>\n\n\n\n<li><strong>\u4f4e\u767a\u73fe\u578b<\/strong>\uff1a\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u304f\u3001\u8001\u5316\u304c\u65e9\u307e\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u5065\u5eb7\u5bff\u547d\u3092\u5ef6\u3070\u3059\u7fd2\u6163<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30ab\u30ed\u30ea\u30fc\u5236\u9650<\/strong>\uff08SIRT1\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u5316\uff09<\/li>\n\n\n\n<li><strong>\u6297\u9178\u5316\u98df\u54c1\u306e\u6442\u53d6<\/strong>\uff08\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3001\u30d3\u30bf\u30df\u30f3E\uff09<\/li>\n\n\n\n<li><strong>\u9069\u5ea6\u306a\u904b\u52d5<\/strong>\uff08\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6d3b\u6027\u5316\uff09<\/li>\n<\/ul>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3001\u5065\u5eb7\u5bff\u547d\u3092\u6700\u5927\u9650\u306b\u4f38\u3070\u3059\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3092\u69cb\u7bc9\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>24. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u672a\u6765\u3068\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u533b\u7642<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-1024x683.jpg\" alt=\"\u672a\u6765\u306e\u533b\u7642\" class=\"wp-image-1075\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30891463_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u533b\u7642\u304c\u9032\u5316\u3057\u3066\u304a\u308a\u3001\u5065\u5eb7\u7ba1\u7406\u306e\u7cbe\u5ea6\u304c\u5411\u4e0a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>AI\u306b\u3088\u308b\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u89e3\u6790\u306e\u9032\u5316<\/strong><\/li>\n\n\n\n<li><strong>\u500b\u5225\u5316\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u958b\u767a<\/strong><\/li>\n\n\n\n<li><strong>\u30d1\u30fc\u30bd\u30ca\u30eb\u30d5\u30a3\u30c3\u30c8\u30cd\u30b9\u306e\u6700\u9069\u5316<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u6280\u8853\u9769\u65b0\u306b\u3088\u308a\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u9078\u629e\u304c\u53ef\u80fd\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator 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class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>1. \u907a\u4f1d\u5b50\u3068\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u95a2\u4fc2 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[&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":10191,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6],"tags":[52,40,41,59,36,49,34,45,55],"class_list":["post-10190","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-basicknowledge","tag-dna-test","tag-privacy","tag-personalized-medicine","tag-59","tag-gene-testing","tag-gene-analysis","tag-genetic-identification","tag-genetics","tag-genetic-diseases"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/10190","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/comments?post=10190"}],"version-history":[{"count":1,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/10190\/revisions"}],"predecessor-version":[{"id":10205,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/10190\/revisions\/10205"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media\/10191"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media?parent=10190"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/categories?post=10190"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/tags?post=10190"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}