{"id":10796,"date":"2025-03-26T04:54:19","date_gmt":"2025-03-26T04:54:19","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=10796"},"modified":"2025-03-26T04:54:20","modified_gmt":"2025-03-26T04:54:20","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e4%bd%93%e5%9e%8b%ef%bc%9a%e9%81%ba%e4%bc%9d%e3%81%8c%e4%b8%8e%e3%81%88%e3%82%8b%e5%bd%b1%e9%9f%bf%e3%82%92%e6%8e%a2%e3%82%8b","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e4%bd%93%e5%9e%8b%ef%bc%9a%e9%81%ba%e4%bc%9d%e3%81%8c%e4%b8%8e%e3%81%88%e3%82%8b%e5%bd%b1%e9%9f%bf%e3%82%92%e6%8e%a2%e3%82%8b\/","title":{"rendered":"\u907a\u4f1d\u5b50\u3068\u4f53\u578b\uff1a\u907a\u4f1d\u304c\u4e0e\u3048\u308b\u5f71\u97ff\u3092\u63a2\u308b"},"content":{"rendered":"\n<p>\u4eba\u9593\u306e\u4f53\u578b\u3084\u4f53\u91cd\u306f\u3001\u74b0\u5883\u8981\u56e0\u3068\u907a\u4f1d\u7684\u8981\u56e0\u306e\u8907\u96d1\u306a\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u6c7a\u5b9a\u3055\u308c\u307e\u3059\u3002\u8fd1\u5e74\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u80a5\u6e80\u3084\u8102\u80aa\u5206\u5e03\u306b\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u4f53\u578b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50\u3068\u305d\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>FTO\u907a\u4f1d\u5b50\u3068\u80a5\u6e80\u306e\u95a2\u9023\u6027<\/strong><\/h2>\n\n\n\n<p><strong>FTO\u907a\u4f1d\u5b50<\/strong>\uff08Fat Mass and Obesity-associated gene\uff09\u306f\u3001\u80a5\u6e80\u3068\u306e\u95a2\u9023\u6027\u304c\u6700\u3082\u5f37\u304f\u793a\u3055\u308c\u3066\u3044\u308b\u907a\u4f1d\u5b50\u306e\u4e00\u3064\u3067\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u4e00\u5869\u57fa\u591a\u578b\uff08SNP\uff09\u3001\u4f8b\u3048\u3070rs9939609\u306f\u3001\u4f53\u91cd\u5897\u52a0\u3084BMI\uff08\u4f53\u683c\u6307\u6570\uff09\u306e\u4e0a\u6607\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u306b\u3088\u308c\u3070\u3001FTO\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u98df\u6b32\u306e\u5897\u52a0\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u6442\u53d6\u91cf\u306e\u5897\u52a0\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>PPARG\u907a\u4f1d\u5b50\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u30d0\u30e9\u30f3\u30b9<\/strong><\/h2>\n\n\n\n<p><strong>PPARG\u907a\u4f1d\u5b50<\/strong>\uff08Peroxisome Proliferator-Activated Receptor Gamma\uff09\u306f\u3001\u8102\u80aa\u7d30\u80de\u306e\u5206\u5316\u3084\u8102\u8cea\u4ee3\u8b1d\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u306e\u8abf\u7bc0\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u591a\u578b\u3001\u7279\u306bPro12Ala\u5909\u7570\u306f\u3001\u80a5\u6e80\u3084\u4f53\u7d44\u6210\u306e\u5909\u5316\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002PPARG\u306f\u30a8\u30cd\u30eb\u30ae\u30fc\u30d0\u30e9\u30f3\u30b9\u306e\u4e3b\u8981\u306a\u8abf\u7bc0\u56e0\u5b50\u3067\u3042\u308a\u3001\u305d\u306e\u5909\u7570\u304c\u30a8\u30cd\u30eb\u30ae\u30fc\u306e\u84c4\u7a4d\u3084\u6d88\u8cbb\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u4f53\u8102\u80aa\u5206\u5e03\u3068\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h2>\n\n\n\n<p>\u4f53\u8102\u80aa\u306e\u5206\u5e03\u3001\u7279\u306b\u5185\u81d3\u8102\u80aa\u3068\u76ae\u4e0b\u8102\u80aa\u306e\u5272\u5408\u306f\u3001\u5065\u5eb7\u30ea\u30b9\u30af\u306b\u5927\u304d\u304f\u5f71\u97ff\u3057\u307e\u3059\u3002\u30a6\u30a8\u30b9\u30c8\u30fb\u30d2\u30c3\u30d7\u6bd4\uff08WHR\uff09\u306f\u4f53\u8102\u80aa\u5206\u5e03\u306e\u6307\u6a19\u3068\u3057\u3066\u7528\u3044\u3089\u308c\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u305d\u306e\u5909\u52d5\u306e\u7d0460%\u3092\u5360\u3081\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u8102\u80aa\u5206\u5e03\u306e\u5909\u5316\u306b\u95a2\u9023\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u304c\u4ee3\u8b1d\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u6027\u5dee\u3068\u8102\u80aa\u5206\u5e03\u306e\u907a\u4f1d\u7684\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<p>\u8102\u80aa\u5206\u5e03\u306b\u95a2\u3059\u308b\u907a\u4f1d\u7684\u5f71\u97ff\u306f\u6027\u5225\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u5973\u6027\u3067\u306f\u4e0b\u534a\u8eab\u3078\u306e\u8102\u80aa\u84c4\u7a4d\u304c\u591a\u304f\u3001\u7537\u6027\u3067\u306f\u8179\u90e8\u3078\u306e\u8102\u80aa\u84c4\u7a4d\u304c\u591a\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u6027\u5dee\u306f\u3001\u907a\u4f1d\u5b50\u3068\u30db\u30eb\u30e2\u30f3\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u308b\u3082\u306e\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>MC4R\u907a\u4f1d\u5b50\u3068\u98df\u6b32\u8abf\u7bc0<\/strong><\/h2>\n\n\n\n<p><strong>MC4R\u907a\u4f1d\u5b50<\/strong>\uff08Melanocortin 4 Receptor\uff09\u306f\u3001\u98df\u6b32\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u306e\u8abf\u7bc0\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u904e\u98df\u3084\u80a5\u6e80\u306e\u30ea\u30b9\u30af\u5897\u52a0\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002MC4R\u306e\u6a5f\u80fd\u4e0d\u5168\u306f\u3001\u6e80\u8179\u611f\u306e\u4f4e\u4e0b\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u306e\u6e1b\u5c11\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u74b0\u5883\u306e\u76f8\u4e92\u4f5c\u7528<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u7684\u8981\u56e0\u306f\u4f53\u578b\u3084\u80a5\u6e80\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u304c\u3001\u74b0\u5883\u8981\u56e0\u3001\u7279\u306b\u98df\u751f\u6d3b\u3084\u904b\u52d5\u7fd2\u6163\u3082\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001FTO\u907a\u4f1d\u5b50\u306e\u30ea\u30b9\u30af\u5909\u7570\u3092\u6301\u3064\u4eba\u3067\u3082\u3001\u5b9a\u671f\u7684\u306a\u8eab\u4f53\u6d3b\u52d5\u306b\u3088\u3063\u3066\u80a5\u6e80\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3067\u304d\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u6700\u8fd1\u306e\u7814\u7a76\u52d5\u5411<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u89e3\u6790\uff08GWAS\uff09\u306b\u3088\u308a\u3001\u4f53\u8102\u80aa\u5206\u5e03\u3084\u80a5\u6e80\u306b\u95a2\u9023\u3059\u308b\u65b0\u305f\u306a\u907a\u4f1d\u5b50\u304c\u591a\u6570\u540c\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u77e5\u898b\u306f\u3001\u500b\u5225\u5316\u533b\u7642\u3084\u4e88\u9632\u533b\u5b66\u306e\u767a\u5c55\u306b\u5bc4\u4e0e\u3059\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002&nbsp;<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u7b4b\u8089\u91cf\u30fb\u4f53\u7d44\u6210\u306e\u95a2\u9023\u6027<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/24007932_m-1024x683.jpg\" alt=\"\n\u90e8\u5c4b\u3067\u7b4b\u30c8\u30ec\u3092\u3059\u308b\u4e2d\u9ad8\u5e74\u5973\u6027\" class=\"wp-image-10804\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/24007932_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/24007932_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/24007932_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/24007932_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/24007932_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u4f53\u578b\u306b\u306f\u8102\u80aa\u306e\u91cf\u3084\u5206\u5e03\u3060\u3051\u3067\u306a\u304f\u3001\u7b4b\u8089\u91cf\u3082\u5927\u304d\u304f\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002\u7b4b\u8089\u91cf\u306f\u4ee3\u8b1d\u7387\u3084\u57fa\u790e\u4ee3\u8b1d\u306b\u5f71\u97ff\u3057\u3001\u592a\u308a\u306b\u304f\u3044\u4f53\u8cea\u306b\u3082\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002\u7b4b\u8089\u91cf\u306e\u500b\u4eba\u5dee\u306b\u3082\u907a\u4f1d\u5b50\u304c\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u591a\u578b\u304c\u7b4b\u7e4a\u7dad\u306e\u69cb\u6210\u3084\u7b4b\u8089\u306e\u767a\u9054\u30b9\u30d4\u30fc\u30c9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001**ACTN3\uff08\u30a2\u30eb\u30d5\u30a1\u30fb\u30a2\u30af\u30c1\u30cb\u30f33\uff09**\u3068\u3044\u3046\u907a\u4f1d\u5b50\u306f\u901f\u7b4b\u7dda\u7dad\u306e\u6a5f\u80fd\u306b\u95a2\u4fc2\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u591a\u578b\uff08R577X\uff09\u304c\u3042\u308b\u3068\u3001\u7206\u767a\u7684\u306a\u7b4b\u529b\u3084\u30b9\u30d7\u30ea\u30f3\u30c8\u529b\u304c\u9ad8\u307e\u308b\u3068\u3055\u308c\u307e\u3059\u3002\u4e00\u65b9\u3001\u3053\u306e\u5909\u7570\u306b\u3088\u3063\u3066ACTN3\u30bf\u30f3\u30d1\u30af\u304c\u767a\u73fe\u3057\u306a\u3044\u5834\u5408\u306f\u3001\u6301\u4e45\u529b\u7cfb\u306e\u904b\u52d5\u306b\u9069\u3057\u305f\u7b4b\u69cb\u6210\u3068\u306a\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u7b4b\u8089\u306e\u30bf\u30a4\u30d7\u306e\u9055\u3044\u306f\u3001\u4f53\u578b\u306b\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u3088\u308a\u7b4b\u8089\u8cea\u3067\u5f15\u304d\u7de0\u307e\u3063\u305f\u4f53\u578b\u306b\u306a\u308b\u304b\u3001\u6bd4\u8f03\u7684\u30b9\u30ea\u30e0\u3067\u6301\u4e45\u529b\u306b\u512a\u308c\u305f\u4f53\u578b\u306b\u306a\u308b\u304b\u306b\u53cd\u6620\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001**MSTN\uff08\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\uff09**\u3068\u3044\u3046\u7b4b\u8089\u306e\u6210\u9577\u3092\u6291\u5236\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3082\u3001\u7b4b\u80a5\u5927\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002MSTN\u306e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3059\u308b\u3068\u3001\u7b4b\u8089\u91cf\u304c\u5897\u52a0\u3057\u3084\u3059\u304f\u306a\u308a\u3001\u4ee3\u8b1d\u304c\u9ad8\u3044\u4f53\u578b\u306b\u306a\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u907a\u4f1d\u5b50\u306f\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u4f53\u578b\u5206\u6790\u3084\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5\u306e\u500b\u5225\u6700\u9069\u5316\u306b\u3082\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u9aa8\u683c\u69cb\u9020\u3068\u907a\u4f1d\u306e\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>\u4f53\u578b\u3092\u6c7a\u5b9a\u3065\u3051\u308b\u91cd\u8981\u306a\u8981\u7d20\u306e\u3072\u3068\u3064\u304c\u3001\u9aa8\u683c\u69cb\u9020\u3067\u3059\u3002\u8eab\u9577\u3001\u80a9\u5e45\u3001\u9aa8\u76e4\u306e\u5e83\u3055\u306a\u3069\u306f\u3001\u907a\u4f1d\u7684\u5f71\u97ff\u3092\u5f37\u304f\u53d7\u3051\u308b\u7279\u5fb4\u3067\u3042\u308a\u3001\u3053\u308c\u3089\u306f\u57fa\u790e\u7684\u306a\u4f53\u578b\u306e\u30d9\u30fc\u30b9\u3092\u5f62\u6210\u3057\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001<strong>HMGA2<\/strong>\u3084<strong>GDF5<\/strong>\u306a\u3069\u306e\u907a\u4f1d\u5b50\u306f\u3001\u6210\u9577\u904e\u7a0b\u306b\u304a\u3051\u308b\u9aa8\u683c\u306e\u767a\u9054\u3084\u8eab\u9577\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u6210\u9577\u30db\u30eb\u30e2\u30f3\u3068\u306e\u9023\u643a\u306b\u3088\u3063\u3066\u9aa8\u306e\u4f38\u9577\u3092\u8abf\u7bc0\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3001<strong>RUNX2<\/strong>\u306f\u9aa8\u5f62\u6210\u306b\u95a2\u4e0e\u3059\u308b\u8ee2\u5199\u56e0\u5b50\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u9aa8\u306e\u5bc6\u5ea6\u3084\u69cb\u9020\u306b\u3082\u95a2\u308f\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u9aa8\u683c\u304c\u3057\u3063\u304b\u308a\u3057\u3066\u3044\u308b\u4f53\u578b\u306e\u4eba\u306f\u3001\u540c\u3058\u4f53\u8102\u80aa\u7387\u3067\u3082\u898b\u305f\u76ee\u306e\u5370\u8c61\u304c\u5f15\u304d\u7de0\u307e\u3063\u3066\u898b\u3048\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u9055\u3044\u3082\u3001\u5358\u306a\u308b\u4f53\u91cd\u3084BMI\u3067\u306f\u8aac\u660e\u3067\u304d\u306a\u3044\u3001\u907a\u4f1d\u306b\u57fa\u3065\u304f\u4f53\u578b\u306e\u5dee\u306e\u4e00\u56e0\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u9aa8\u5bc6\u5ea6\u306b\u95a2\u3057\u3066\u306f<strong>LRP5<\/strong>\u907a\u4f1d\u5b50\u304c\u77e5\u3089\u308c\u3066\u304a\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3088\u3063\u3066\u9aa8\u7c97\u9b06\u75c7\u306e\u30ea\u30b9\u30af\u3084\u9aa8\u306e\u5f37\u3055\u306b\u5dee\u304c\u51fa\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u9aa8\u5bc6\u5ea6\u304c\u9ad8\u3051\u308c\u3070\u3001\u4f53\u91cd\u304c\u3042\u3063\u3066\u3082\u5f15\u304d\u7de0\u307e\u3063\u3066\u898b\u3048\u308b\u4f53\u578b\u3092\u4fdd\u3061\u3084\u3059\u304f\u3001\u4ee3\u8b1d\u306b\u3082\u6709\u5229\u306b\u50cd\u304f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u98df\u7fd2\u6163\u3068\u4f53\u578b\u306b\u95a2\u3059\u308b\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"574\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/29326592_m-1024x574.jpg\" alt=\"\n\u30e1\u30bf\u30dc\u3068\u98df\u4e8b\u2464\" class=\"wp-image-10811\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29326592_m-1024x574.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29326592_m-300x168.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29326592_m-768x430.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29326592_m-1536x861.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29326592_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u98df\u4e8b\u306b\u5bfe\u3059\u308b\u55dc\u597d\u3084\u6e80\u8179\u611f\u306e\u611f\u3058\u65b9\u3082\u3001\u4f53\u578b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u8981\u56e0\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u8981\u7d20\u3082\u307e\u305f\u907a\u4f1d\u5b50\u306b\u3088\u308a\u5de6\u53f3\u3055\u308c\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001**LEPR\uff08\u30ec\u30d7\u30c1\u30f3\u53d7\u5bb9\u4f53\uff09**\u907a\u4f1d\u5b50\u306f\u98df\u6b32\u306e\u5236\u5fa1\u306b\u95a2\u4e0e\u3057\u3001\u6e80\u8179\u611f\u306e\u611f\u77e5\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u30ec\u30d7\u30c1\u30f3\u306f\u8102\u80aa\u7d30\u80de\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3001\u8133\u306e\u8996\u5e8a\u4e0b\u90e8\u306b\u4f5c\u7528\u3057\u3066\u98df\u6b32\u3092\u6291\u5236\u3057\u307e\u3059\u304c\u3001LEPR\u306e\u611f\u53d7\u6027\u304c\u4f4e\u3044\u3068\u3001\u904e\u98df\u50be\u5411\u3068\u306a\u308a\u3084\u3059\u3044\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001<strong>TAS2R38<\/strong>\u3068\u3044\u3046\u5473\u899a\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\u306f\u3001\u82e6\u5473\u306e\u611f\u77e5\u80fd\u529b\u306b\u95a2\u4fc2\u3057\u3066\u304a\u308a\u3001\u91ce\u83dc\u3084\u82e6\u5473\u306e\u3042\u308b\u98df\u6750\u3092\u907f\u3051\u308b\u50be\u5411\u3092\u5f62\u6210\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306b\u3088\u308a\u3001\u30d6\u30ed\u30c3\u30b3\u30ea\u30fc\u3084\u30b1\u30fc\u30eb\u306a\u3069\u306e\u6442\u53d6\u91cf\u304c\u6e1b\u308a\u3001\u7d50\u679c\u7684\u306b\u98df\u7269\u7e4a\u7dad\u3084\u6297\u9178\u5316\u7269\u8cea\u306e\u6442\u53d6\u91cf\u304c\u5c11\u306a\u304f\u306a\u308a\u3001\u4f53\u8102\u80aa\u7387\u306e\u5897\u52a0\u3084\u4ee3\u8b1d\u7570\u5e38\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u30b1\u30fc\u30b9\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001<strong>FABP2<\/strong>\u907a\u4f1d\u5b50\u306f\u8102\u8cea\u5438\u53ce\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u591a\u578b\u3092\u6301\u3064\u4eba\u306f\u8102\u80aa\u306e\u5438\u53ce\u7387\u304c\u9ad8\u3044\u305f\u3081\u3001\u540c\u3058\u98df\u4e8b\u3067\u3082\u4f53\u8102\u80aa\u3068\u3057\u3066\u84c4\u7a4d\u3057\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u77e5\u898b\u3092\u3082\u3068\u306b\u3001\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u3055\u308c\u305f\u98df\u4e8b\u8a2d\u8a08\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u7387\u7684\u306b\u4f53\u578b\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7761\u7720\u3068\u4f53\u578b\u306b\u95a2\u3059\u308b\u907a\u4f1d\u7684\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>\u7761\u7720\u306e\u8cea\u3084\u30d1\u30bf\u30fc\u30f3\u3082\u3001\u4f53\u578b\u306e\u5f62\u6210\u306b\u5927\u304d\u304f\u5f71\u97ff\u3059\u308b\u8981\u56e0\u306e\u3072\u3068\u3064\u3067\u3059\u3002\u7761\u7720\u4e0d\u8db3\u3084\u7761\u7720\u306e\u8cea\u306e\u4f4e\u4e0b\u306f\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3092\u4e71\u3057\u3001\u98df\u6b32\u5897\u52a0\u3084\u4ee3\u8b1d\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u7761\u7720\u50be\u5411\u81ea\u4f53\u306b\u3082\u907a\u4f1d\u7684\u306a\u8981\u56e0\u304c\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u7761\u7720\u30d1\u30bf\u30fc\u30f3\u3084\u8cea\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001<strong>PER2<\/strong>\u3084<strong>CLOCK<\/strong>\u3068\u3044\u3063\u305f\u300c\u6642\u8a08\u907a\u4f1d\u5b50\u300d\u306f\u6982\u65e5\u30ea\u30ba\u30e0\uff08\u30b5\u30fc\u30ab\u30c7\u30a3\u30a2\u30f3\u30ea\u30ba\u30e0\uff09\u306e\u8abf\u7bc0\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u591c\u578b\u306e\u751f\u6d3b\u7fd2\u6163\u306b\u306a\u308a\u3084\u3059\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u591c\u578b\u306e\u4eba\u306f\u591c\u9593\u306b\u904e\u5270\u306a\u30ab\u30ed\u30ea\u30fc\u6442\u53d6\u3092\u884c\u3044\u3084\u3059\u304f\u3001\u8102\u80aa\u306e\u84c4\u7a4d\u3084\u80a5\u6e80\u306b\u3064\u306a\u304c\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001<strong>ABCC9<\/strong>\u3068\u3044\u3046\u907a\u4f1d\u5b50\u3082\u3001\u7761\u7720\u6642\u9593\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u304a\u308a\u3001\u907a\u4f1d\u7684\u306b\u300c\u77ed\u6642\u9593\u7761\u7720\u300d\u304c\u6700\u9069\u306a\u4eba\u3082\u3044\u308c\u3070\u3001\u3088\u308a\u9577\u6642\u9593\u306e\u7761\u7720\u3092\u5fc5\u8981\u3068\u3059\u308b\u4eba\u3082\u3044\u307e\u3059\u3002\u5fc5\u8981\u306a\u7761\u7720\u6642\u9593\u304c\u78ba\u4fdd\u3055\u308c\u306a\u3044\u5834\u5408\u3001\u30ec\u30d7\u30c1\u30f3\u3068\u30b0\u30ec\u30ea\u30f3\u3068\u3044\u3046\u98df\u6b32\u306b\u95a2\u9023\u3059\u308b\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u304c\u5d29\u308c\u3001\u904e\u98df\u3092\u8a98\u767a\u3057\u3001\u4f53\u91cd\u5897\u52a0\u306b\u3064\u306a\u304c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7761\u7720\u3068\u4f53\u578b\u306e\u95a2\u4fc2\u306b\u7740\u76ee\u3057\u305f\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u306f\u3001\u4f53\u5185\u6642\u8a08\u306e\u4e71\u308c\u304c\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3092\u9ad8\u3081\u3001\u7cd6\u4ee3\u8b1d\u7570\u5e38\u3092\u62db\u304f\u3053\u3068\u3082\u793a\u5506\u3055\u308c\u3066\u304a\u308a\u3001\u4ee3\u8b1d\u6027\u75be\u60a3\u306e\u30ea\u30b9\u30af\u56e0\u5b50\u306e\u3072\u3068\u3064\u3068\u3057\u3066\u7761\u7720\u304c\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u3068\u4f53\u8102\u80aa\u84c4\u7a4d\u306e\u907a\u4f1d\u7684\u80cc\u666f<\/strong><\/h3>\n\n\n\n<p>\u7cbe\u795e\u7684\u30fb\u8eab\u4f53\u7684\u306a\u30b9\u30c8\u30ec\u30b9\u306f\u3001\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u3068\u3044\u3046\u30db\u30eb\u30e2\u30f3\u3092\u4ecb\u3057\u3066\u8102\u80aa\u306e\u84c4\u7a4d\u3084\u7b4b\u8089\u306e\u5206\u89e3\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u3053\u306e\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u306e\u611f\u53d7\u6027\u3082\u307e\u305f\u3001\u907a\u4f1d\u7684\u306b\u6c7a\u5b9a\u3055\u308c\u308b\u90e8\u5206\u304c\u5927\u304d\u304f\u3001\u4f53\u578b\u5f62\u6210\u306b\u9593\u63a5\u7684\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001<strong>FKBP5<\/strong>\u3084<strong>NR3C1<\/strong>\u3068\u3044\u3063\u305f\u907a\u4f1d\u5b50\u306f\u3001\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u53d7\u5bb9\u4f53\u306b\u95a2\u4e0e\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u540c\u3058\u30b9\u30c8\u30ec\u30b9\u3092\u53d7\u3051\u3066\u3082\u4f53\u8102\u80aa\u304c\u84c4\u7a4d\u3057\u3084\u3059\u304f\u306a\u3063\u305f\u308a\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u308a\u904e\u98df\u306b\u8d70\u308a\u3084\u3059\u304f\u306a\u3063\u305f\u308a\u3059\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u6162\u6027\u7684\u306a\u30b9\u30c8\u30ec\u30b9\u72b6\u614b\u3067\u306f\u3001\u7279\u306b\u8179\u90e8\u8102\u80aa\u304c\u5897\u52a0\u3057\u3084\u3059\u3044\u3068\u3055\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u306f\u300c\u5185\u81d3\u8102\u80aa\u578b\u80a5\u6e80\u300d\u3084\u300c\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u300d\u306e\u8981\u56e0\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u72b6\u614b\u306f\u3001\u5358\u306a\u308b\u4f53\u91cd\u5897\u52a0\u3068\u306f\u7570\u306a\u308a\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u3084\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u5371\u967a\u306a\u4f53\u578b\u5909\u5316\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u5bfe\u51e6\u80fd\u529b\u306b\u3082\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u305d\u306e\u57fa\u76e4\u306b\u306f<strong>COMT<\/strong>\uff08\u30ab\u30c6\u30b3\u30fc\u30eb-O-\u30e1\u30c1\u30eb\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc\uff09\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u5206\u89e3\u901f\u5ea6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3084\u60c5\u7dd2\u306e\u5b89\u5b9a\u6027\u306b\u95a2\u4fc2\u3057\u307e\u3059\u3002\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u3063\u3066\u4f53\u578b\u304c\u5909\u5316\u3057\u3084\u3059\u3044\u4eba\u306f\u3001\u3053\u306e\u3088\u3046\u306a\u907a\u4f1d\u7684\u8981\u7d20\u3092\u6301\u3063\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2\u3082\u4f53\u578b\u7ba1\u7406\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u8996\u70b9\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b\u4f53\u578b\u30bf\u30a4\u30d7\u306e\u5206\u985e\u3068\u6d3b\u7528<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31942660_m-1024x768.jpg\" alt=\"\n\u7761\u7720\" class=\"wp-image-10818\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31942660_m-1024x768.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31942660_m-300x225.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31942660_m-768x576.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31942660_m-1536x1152.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31942660_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30d8\u30eb\u30b9\u306e\u5206\u91ce\u3067\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u57fa\u306b\u4f53\u578b\u306e\u50be\u5411\u3084\u5909\u5316\u306e\u3057\u3084\u3059\u3055\u3092\u5206\u985e\u3059\u308b\u53d6\u308a\u7d44\u307f\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u691c\u67fb\u3067\u306f\u3001\u80a5\u6e80\u30ea\u30b9\u30af\u3001\u7b4b\u8089\u91cf\u3001\u8102\u80aa\u5206\u5e03\u3001\u4ee3\u8b1d\u7387\u3001\u98df\u6b32\u50be\u5411\u3001\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u3001\u7761\u7720\u30d1\u30bf\u30fc\u30f3\u306a\u3069\u3001\u591a\u89d2\u7684\u306a\u60c5\u5831\u304c\u5f97\u3089\u308c\u3001\u305d\u308c\u305e\u308c\u306e\u7279\u6027\u306b\u5fdc\u3058\u305f\u5bfe\u7b56\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u540c\u3058\u30c0\u30a4\u30a8\u30c3\u30c8\u30d7\u30e9\u30f3\u3092\u5b9f\u8df5\u3057\u3066\u3082\u3001\u8102\u80aa\u304c\u843d\u3061\u3084\u3059\u3044\u4eba\u3068\u7b4b\u8089\u304c\u843d\u3061\u3084\u3059\u3044\u4eba\u304c\u3044\u307e\u3059\u304c\u3001\u305d\u308c\u306f\u300c\u8102\u8cea\u4ee3\u8b1d\u578b\u300d\u304b\u300c\u7cd6\u4ee3\u8b1d\u578b\u300d\u304b\u3068\u3044\u3063\u305f\u907a\u4f1d\u7684\u7279\u5fb4\u306b\u8d77\u56e0\u3057\u3066\u3044\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u524d\u8005\u306b\u306f\u9ad8\u8102\u80aa\u98df\u306e\u5236\u9650\u3001\u5f8c\u8005\u306b\u306f\u4f4e\u7cd6\u8cea\u98df\u306e\u5c0e\u5165\u304c\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u7b4b\u8089\u304c\u3064\u304d\u306b\u304f\u3044\u907a\u4f1d\u7684\u30bf\u30a4\u30d7\u306e\u4eba\u306b\u306f\u3001\u7279\u5b9a\u306e\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u30d7\u30ed\u30c6\u30a4\u30f3\u6442\u53d6\u306e\u30bf\u30a4\u30df\u30f3\u30b0\u306e\u6700\u9069\u5316\u304c\u63a8\u5968\u3055\u308c\u308b\u306a\u3069\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u57fa\u3065\u304f\u6226\u7565\u304c\u9ad8\u3044\u6210\u679c\u3092\u4e0a\u3052\u308b\u4e8b\u4f8b\u3082\u591a\u304f\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u60c5\u5831\u306f\u3001\u904b\u52d5\u9078\u624b\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u5411\u4e0a\u3060\u3051\u3067\u306a\u304f\u3001\u4e00\u822c\u306e\u4eba\u3005\u306e\u5065\u5eb7\u5897\u9032\u3084\u4f53\u578b\u7dad\u6301\u306b\u3082\u5e83\u304f\u5fdc\u7528\u3055\u308c\u3066\u304a\u308a\u3001\u4eca\u5f8c\u3055\u3089\u306b\u8eab\u8fd1\u306a\u6280\u8853\u3068\u3057\u3066\u666e\u53ca\u3057\u3066\u3044\u304f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u4f53\u578b\u306e\u5909\u5316<\/strong><\/h3>\n\n\n\n<p>\u4f53\u578b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u907a\u4f1d\u7684\u8981\u56e0\u3068\u3057\u3066\u3001DNA\u914d\u5217\u305d\u306e\u3082\u306e\u306b\u52a0\u3048\u3066\u300c<strong>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9<\/strong>\u300d\u306e\u5f79\u5272\u3082\u7121\u8996\u3067\u304d\u307e\u305b\u3093\u3002\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u306f\u3001DNA\u306e\u5869\u57fa\u914d\u5217\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068\u306a\u304f\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u91cf\u3092\u8abf\u7bc0\u3059\u308b\u4ed5\u7d44\u307f\u3092\u6307\u3057\u307e\u3059\u3002\u4ee3\u8868\u7684\u306a\u3082\u306e\u306b\u306f\u3001<strong>DNA\u30e1\u30c1\u30eb\u5316<\/strong>\u3084<strong>\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe<\/strong>\u306a\u3069\u304c\u3042\u308a\u3001\u751f\u6d3b\u7fd2\u6163\u3084\u74b0\u5883\u56e0\u5b50\u306b\u3088\u3063\u3066\u5909\u5316\u3059\u308b\u306e\u304c\u7279\u5fb4\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001\u98df\u4e8b\u306e\u5185\u5bb9\u3001\u904b\u52d5\u7fd2\u6163\u3001\u30b9\u30c8\u30ec\u30b9\u3001\u7761\u7720\u306e\u8cea\u306a\u3069\u304c\u3001\u7279\u5b9a\u306e\u4ee3\u8b1d\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u4fc3\u9032\u307e\u305f\u306f\u6291\u5236\u3059\u308b\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u540c\u3058\u907a\u4f1d\u7684\u80cc\u666f\u3092\u6301\u3063\u3066\u3044\u3066\u3082\u3001\u74b0\u5883\u306b\u3088\u3063\u3066\u4f53\u578b\u3084\u80a5\u6e80\u30ea\u30b9\u30af\u304c\u5909\u52d5\u3059\u308b\u3068\u3044\u3046\u73fe\u8c61\u304c\u8aac\u660e\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5b9f\u969b\u3001<strong>PPAR\u03b3\u907a\u4f1d\u5b50\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u9818\u57df\u306e\u30e1\u30c1\u30eb\u5316\u72b6\u614b<\/strong>\u304c\u8102\u80aa\u7d30\u80de\u306e\u5206\u5316\u3084\u8102\u8cea\u84c4\u7a4d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u4f53\u8102\u80aa\u7387\u306b\u76f4\u63a5\u7684\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001**IGF2\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u6210\u9577\u56e0\u5b502\uff09**\u306e\u30e1\u30c1\u30eb\u5316\u7570\u5e38\u306f\u3001\u51fa\u751f\u4f53\u91cd\u3068\u5c06\u6765\u7684\u306a\u80a5\u6e80\u30ea\u30b9\u30af\u3068\u306e\u95a2\u9023\u6027\u3092\u793a\u5506\u3059\u308b\u3082\u306e\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u5909\u5316\u306f\u53ef\u9006\u7684\u3067\u3042\u308b\u3053\u3068\u304b\u3089\u3001\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u306b\u3088\u3063\u3066\u4f53\u578b\u3084\u4ee3\u8b1d\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6700\u9069\u5316\u3059\u308b\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u304a\u308a\u3001\u7279\u306b<strong>\u5b50\u3069\u3082\u3084\u598a\u5a20\u4e2d\u306e\u6bcd\u89aa<\/strong>\u306b\u5bfe\u3057\u3066\u306f\u300c\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u30fb\u30d7\u30ed\u30b0\u30e9\u30df\u30f3\u30b0\u300d\u306e\u89b3\u70b9\u304b\u3089\u6804\u990a\u6307\u5c0e\u304c\u884c\u308f\u308c\u308b\u30b1\u30fc\u30b9\u3082\u5897\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u5730\u57df\u30fb\u6c11\u65cf\u306b\u3088\u308b\u907a\u4f1d\u7684\u4f53\u578b\u50be\u5411\u306e\u9055\u3044<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/4085976_m-1024x683.jpg\" alt=\"\n\u30ab\u30e1\u30e9\u76ee\u7dda\u306e\u5973\u306e\u5b50\u305f\u3061\" class=\"wp-image-10825\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4085976_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4085976_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4085976_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4085976_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4085976_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" 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class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u7684\u4f53\u578b\u60c5\u5831\u306e\u5fdc\u7528\uff1a\u30b9\u30dd\u30fc\u30c4\u79d1\u5b66\u30fb\u7f8e\u5bb9\u533b\u7642\u306e\u5206\u91ce\u3067\u306e\u6d3b\u7528<\/strong><\/h3>\n\n\n\n<p>\u4f53\u578b\u306b\u95a2\u3059\u308b\u907a\u4f1d\u7684\u60c5\u5831\u306f\u3001\u533b\u7642\u3084\u5065\u5eb7\u6307\u5c0e\u306b\u9650\u3089\u305a\u3001\u30b9\u30dd\u30fc\u30c4\u79d1\u5b66\u3084\u7f8e\u5bb9\u533b\u7642\u306e\u5206\u91ce\u3067\u3082\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001<strong>\u30a2\u30b9\u30ea\u30fc\u30c8\u5411\u3051\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30ed\u30b0\u30e9\u30e0<\/strong>\u3067\u306f\u3001ACTN3\u3084ACE\u907a\u4f1d\u5b50\u306a\u3069\u3001\u7b4b\u529b\u30fb\u6301\u4e45\u529b\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u57fa\u3065\u3044\u3066\u3001\u6700\u9069\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3084\u6804\u990a\u6226\u7565\u3092\u500b\u5225\u306b\u8a2d\u8a08\u3059\u308b\u30b1\u30fc\u30b9\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3001\u7f8e\u5bb9\u533b\u7642\u3067\u306f\u3001\u8102\u80aa\u5438\u5f15\u3084\u30dc\u30c7\u30a3\u30b9\u30ab\u30eb\u30d7\u30c6\u30a3\u30f3\u30b0\u306e\u969b\u306b\u3001\u8102\u80aa\u306e\u4ed8\u304d\u3084\u3059\u3055\u3084\u76ae\u819a\u306e\u305f\u308b\u307f\u3084\u3059\u3055\u3092\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u8e0f\u307e\u3048\u3066\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3059\u308b\u30af\u30ea\u30cb\u30c3\u30af\u3082\u767b\u5834\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306b**COL1A1\uff08\u30b3\u30e9\u30fc\u30b2\u30f3\u907a\u4f1d\u5b50\uff09**\u306a\u3069\u3001\u76ae\u819a\u306e\u5f3e\u529b\u3084\u52a0\u9f62\u306b\u3088\u308b\u5909\u5316\u306b\u95a2\u4fc2\u3059\u308b\u907a\u4f1d\u5b50\u306e\u60c5\u5831\u306f\u3001\u30a8\u30a4\u30b8\u30f3\u30b0\u30b1\u30a2\u3084\u30dc\u30c7\u30a3\u30c7\u30b6\u30a4\u30f3\u306e\u6307\u6a19\u3068\u3057\u3066\u91cd\u5b9d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3084\u6a5f\u80fd\u6027\u98df\u54c1\u306e\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u63d0\u6848\u306b\u3082\u3001\u4f53\u578b\u95a2\u9023\u907a\u4f1d\u5b50\u304c\u5229\u7528\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u8102\u80aa\u71c3\u713c\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u30b5\u30d7\u30ea\u3092\u9078\u3076\u969b\u306b\u3001UCP2\u3084PPARGC1A\u306a\u3069\u306e\u907a\u4f1d\u7684\u30c7\u30fc\u30bf\u3092\u3082\u3068\u306b\u52b9\u679c\u3092\u4e88\u6e2c\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u79d1\u5b66\u7684\u6839\u62e0\u306b\u57fa\u3065\u3044\u305f\u9078\u629e\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u4ee3\u8b1d\u30bf\u30a4\u30d7\u5225\u4f53\u578b\u306e\u907a\u4f1d\u7684\u5206\u985e<\/strong><\/h3>\n\n\n\n<p>\u4f53\u578b\u306b\u95a2\u9023\u3059\u308b\u4ee3\u8b1d\u306e\u7279\u6027\u306f\u3001\u5927\u304d\u304f\u300c\u7cd6\u4ee3\u8b1d\u512a\u4f4d\u578b\u300d\u300c\u8102\u8cea\u4ee3\u8b1d\u512a\u4f4d\u578b\u300d\u300c\u305f\u3093\u3071\u304f\u8cea\u4ee3\u8b1d\u578b\u300d\u306a\u3069\u306b\u5206\u985e\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u3053\u3046\u3057\u305f\u4ee3\u8b1d\u30bf\u30a4\u30d7\u306b\u306f\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u304c\u8272\u6fc3\u304f\u53cd\u6620\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001<strong>IRS1\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u53d7\u5bb9\u4f53\u57fa\u8cea1\uff09\u3084TCF7L2<\/strong>\u3068\u3044\u3063\u305f\u7cd6\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3001\u7cd6\u8cea\u306e\u4ee3\u8b1d\u52b9\u7387\u304c\u60aa\u304f\u3001\u8840\u7cd6\u5024\u306e\u4e0a\u6607\u304c\u9577\u304f\u7d9a\u304f\u50be\u5411\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u4eba\u306f\u3001\u9ad8\u7cd6\u8cea\u306a\u98df\u4e8b\u306b\u3088\u3063\u3066\u8102\u80aa\u304c\u84c4\u7a4d\u3057\u3084\u3059\u304f\u3001\u7279\u306b\u8179\u90e8\u80a5\u6e80\u578b\u306e\u4f53\u578b\u306b\u306a\u308a\u3084\u3059\u3044\u3068\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3001<strong>APOA2<\/strong>\u3084<strong>FABP2<\/strong>\u306a\u3069\u306e\u8102\u8cea\u4ee3\u8b1d\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306f\u3001\u8102\u80aa\u306e\u5438\u53ce\u7387\u3084\u84c4\u7a4d\u50be\u5411\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u8102\u8cea\u6442\u53d6\u91cf\u306e\u591a\u5be1\u306b\u3088\u308a\u4f53\u8102\u80aa\u91cf\u304c\u9855\u8457\u306b\u5909\u52d5\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u8102\u8cea\u4ee3\u8b1d\u304c\u5f97\u610f\u306a\u4eba\u306f\u3001\u6bd4\u8f03\u7684\u9ad8\u8102\u8cea\u306a\u98df\u4e8b\u3067\u3082\u4f53\u8102\u80aa\u304c\u3064\u304d\u306b\u304f\u3044\u4e00\u65b9\u3001\u82e6\u624b\u306a\u4eba\u306f\u540c\u3058\u91cf\u3067\u3082\u4f53\u91cd\u304c\u5897\u52a0\u3057\u3084\u3059\u3044\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306a\u4ee3\u8b1d\u306e\u907a\u4f1d\u7684\u50be\u5411\u306f\u3001\u30c0\u30a4\u30a8\u30c3\u30c8\u3084\u30dc\u30c7\u30a3\u30e1\u30a4\u30af\u306e\u8a2d\u8a08\u306b\u304a\u3044\u3066\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002\u7279\u5b9a\u306e\u6804\u990a\u7d20\u5236\u9650\u304c\u5408\u3046\u304b\u3069\u3046\u304b\u3001\u3042\u308b\u3044\u306f\u6709\u9178\u7d20\u904b\u52d5\u3068\u7b4b\u30c8\u30ec\u306e\u3069\u3061\u3089\u304c\u52b9\u679c\u7684\u304b\u3092\u898b\u6975\u3081\u308b\u969b\u306e\u6307\u6a19\u3068\u306a\u308a\u5f97\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u601d\u6625\u671f\u306e\u6210\u9577\u30d1\u30bf\u30fc\u30f3\u3068\u4f53\u578b\u306e\u907a\u4f1d\u7684\u95a2\u9023<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" data-id=\"10832\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31668498_m-1024x683.jpg\" alt=\"\n\u7167\u308c\u304f\u3055\u305d\u3046\u306b\u3059\u308b\u7537\u5973\u306e\u5b66\u751f\" class=\"wp-image-10832\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31668498_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31668498_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31668498_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31668498_m-1536x1025.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31668498_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/figure>\n\n\n\n<p>\u601d\u6625\u671f\u306f\u9aa8\u683c\u3084\u7b4b\u8089\u3001\u8102\u80aa\u7d44\u7e54\u306e\u6025\u901f\u306a\u767a\u9054\u304c\u8d77\u3053\u308b\u6642\u671f\u3067\u3042\u308a\u3001\u3053\u306e\u6642\u671f\u306e\u6210\u9577\u30d1\u30bf\u30fc\u30f3\u304c\u5c06\u6765\u306e\u4f53\u578b\u3092\u5927\u304d\u304f\u5de6\u53f3\u3057\u307e\u3059\u3002\u601d\u6625\u671f\u306e\u6210\u9577\u901f\u5ea6\u3084\u7d42\u4e86\u6642\u671f\u306b\u306f\u3001\u8907\u6570\u306e\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>LIN28B<\/strong>\u3068\u3044\u3046\u907a\u4f1d\u5b50\u306f\u3001\u601d\u6625\u671f\u306e\u958b\u59cb\u6642\u671f\u306b\u95a2\u4e0e\u3059\u308b\u4ee3\u8868\u7684\u306a\u907a\u4f1d\u5b50\u3067\u3042\u308a\u3001\u305d\u306e\u591a\u578b\u306f\u521d\u6f6e\u5e74\u9f62\u3084\u9aa8\u6210\u719f\u306e\u30b9\u30d4\u30fc\u30c9\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u601d\u6625\u671f\u304c\u65e9\u304f\u8a2a\u308c\u308b\u4eba\u306f\u8102\u80aa\u7d44\u7e54\u306e\u5897\u52a0\u304c\u65e9\u304f\u59cb\u307e\u308b\u50be\u5411\u304c\u3042\u308a\u3001\u3053\u308c\u304c\u5c06\u6765\u7684\u306a\u4f53\u8102\u80aa\u7387\u3084\u80a5\u6e80\u50be\u5411\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001**ESR1\uff08\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff09**\u306e\u767a\u73fe\u30d1\u30bf\u30fc\u30f3\u306f\u3001\u5973\u6027\u306e\u4f53\u578b\u5f62\u6210\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u304a\u308a\u3001\u7279\u306b\u9aa8\u76e4\u306e\u5e45\u3084\u4f53\u8102\u80aa\u306e\u5206\u5e03\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u306b\u3088\u3063\u3066\u3001\u4e0b\u534a\u8eab\u592a\u308a\u3084\u6d0b\u30ca\u30b7\u578b\u306e\u4f53\u578b\u304c\u5f62\u6210\u3055\u308c\u3084\u3059\u304f\u306a\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u767a\u9054\u6bb5\u968e\u306b\u304a\u3051\u308b\u907a\u4f1d\u7684\u5f71\u97ff\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u65e9\u671f\u304b\u3089\u9069\u5207\u306a\u6804\u990a\u7ba1\u7406\u3084\u904b\u52d5\u7fd2\u6163\u3092\u5c0e\u5165\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3068\u306a\u308a\u3001\u9577\u671f\u7684\u306a\u4f53\u578b\u3084\u5065\u5eb7\u7dad\u6301\u306b\u5f79\u7acb\u3064\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30db\u30eb\u30e2\u30f3\u611f\u53d7\u6027\u3068\u4f53\u578b\u3078\u306e\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>\u30db\u30eb\u30e2\u30f3\u306f\u4f53\u578b\u306b\u5bfe\u3057\u3066\u975e\u5e38\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u6301\u3063\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u30db\u30eb\u30e2\u30f3\u306e\u611f\u53d7\u6027\u306b\u3082\u907a\u4f1d\u7684\u5dee\u7570\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u7279\u306b\u3001<strong>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3<\/strong>\u3084<strong>\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3<\/strong>\u306a\u3069\u306e\u6027\u30db\u30eb\u30e2\u30f3\u3001<strong>\u30a4\u30f3\u30b9\u30ea\u30f3<\/strong>\u3001<strong>\u6210\u9577\u30db\u30eb\u30e2\u30f3<\/strong>\u3068\u3044\u3063\u305f\u4ee3\u8b1d\u95a2\u9023\u30db\u30eb\u30e2\u30f3\u306f\u3001\u8102\u80aa\u5206\u5e03\u3001\u7b4b\u8089\u91cf\u3001\u4f53\u6c34\u5206\u91cf\u306a\u3069\u306e\u4f53\u7d44\u6210\u3092\u8abf\u6574\u3059\u308b\u4e2d\u5fc3\u7684\u306a\u5b58\u5728\u3067\u3059\u3002<\/p>\n\n\n\n<p>**AR\uff08\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff09**\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306f\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u7b4b\u8089\u91cf\u306e\u3064\u304d\u3084\u3059\u3055\u3084\u4f53\u8102\u80aa\u7387\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002\u7537\u6027\u3067\u3053\u306e\u53d7\u5bb9\u4f53\u306e\u611f\u53d7\u6027\u304c\u9ad8\u3044\u3068\u3001\u7b4b\u8089\u8cea\u306a\u4f53\u578b\u3092\u7dad\u6301\u3057\u3084\u3059\u304f\u3001\u9006\u306b\u611f\u53d7\u6027\u304c\u4f4e\u3044\u3068\u8102\u80aa\u304c\u3064\u304d\u3084\u3059\u304f\u306a\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001<strong>INSR\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u53d7\u5bb9\u4f53\uff09\u3084IGF1<\/strong>\u306a\u3069\u306e\u907a\u4f1d\u5b50\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u306b\u95a2\u4e0e\u3057\u3001\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3084\u8102\u80aa\u5408\u6210\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u304c\u4f4e\u3044\u4eba\u306f\u3001\u540c\u3058\u30ab\u30ed\u30ea\u30fc\u3092\u6442\u53d6\u3057\u3066\u3082\u8102\u80aa\u3068\u3057\u3066\u84c4\u7a4d\u3057\u3084\u3059\u304f\u306a\u308b\u305f\u3081\u3001\u4f53\u578b\u7ba1\u7406\u304c\u96e3\u3057\u304f\u306a\u308a\u304c\u3061\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u5973\u6027\u306b\u304a\u3044\u3066\u306f\u3001<strong>PGR\uff08\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u53d7\u5bb9\u4f53\uff09\u3084ESR1<\/strong>\u3068\u3044\u3063\u305f\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\u306e\u591a\u578b\u304c\u3001\u598a\u5a20\u4e2d\u3084\u66f4\u5e74\u671f\u306e\u4f53\u578b\u5909\u5316\u3001\u7279\u306b\u8102\u80aa\u84c4\u7a4d\u306e\u50be\u5411\u306b\u5f71\u97ff\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u30db\u30eb\u30e2\u30f3\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u907a\u4f1d\u7684\u80cc\u666f\u3092\u6301\u3064\u4eba\u306f\u3001\u30e9\u30a4\u30d5\u30b9\u30c6\u30fc\u30b8\u306b\u5fdc\u3058\u305f\u4f53\u578b\u5909\u5316\u3092\u4e88\u6e2c\u3057\u3001\u3042\u3089\u304b\u3058\u3081\u5bfe\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u5e74\u9f62\u306b\u3088\u308b\u4f53\u578b\u5909\u5316\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31867949_m-1024x683.jpg\" alt=\"\n\u9053\u8def\u3092\u6a2a\u65ad\u3059\u308b\u9ad8\u9f62\u7537\u6027\" class=\"wp-image-10839\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31867949_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31867949_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31867949_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31867949_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31867949_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u5e74\u9f62\u3068\u3068\u3082\u306b\u5909\u5316\u3059\u308b\u4f53\u578b\u306e\u80cc\u666f\u306b\u306f\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3084\u751f\u6d3b\u7fd2\u6163\u306e\u5909\u5316\u3060\u3051\u3067\u306a\u304f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u3082\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u52a0\u9f62\u306b\u4f34\u3044\u57fa\u790e\u4ee3\u8b1d\u304c\u4f4e\u4e0b\u3057\u3001\u7b4b\u8089\u91cf\u304c\u81ea\u7136\u3068\u6e1b\u5c11\u3057\u3084\u3059\u304f\u306a\u308b\u306e\u306f\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306e\u9032\u884c\u901f\u5ea6\u3084\u7a0b\u5ea6\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u305d\u306e\u4e00\u90e8\u304c\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u6c7a\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001<strong>MYOD1<\/strong>\u3084<strong>FOXO3<\/strong>\u3068\u3044\u3063\u305f\u907a\u4f1d\u5b50\u306f\u7b4b\u8089\u306e\u7dad\u6301\u3084\u8001\u5316\u306b\u95a2\u308f\u308b\u91cd\u8981\u306a\u8abf\u7bc0\u56e0\u5b50\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u591a\u578b\u304c\u5b58\u5728\u3059\u308b\u5834\u5408\u3001\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\uff08\u52a0\u9f62\u6027\u7b4b\u8089\u6e1b\u5c11\u75c7\uff09\u306e\u767a\u75c7\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001<strong>SIRT1<\/strong>\u907a\u4f1d\u5b50\u306f\u9577\u5bff\u907a\u4f1d\u5b50\u3068\u3057\u3066\u3082\u6ce8\u76ee\u3055\u308c\u3066\u304a\u308a\u3001\u4ee3\u8b1d\u5236\u5fa1\u3084\u8102\u80aa\u306e\u84c4\u7a4d\u306b\u3082\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u52a0\u9f62\u3068\u3068\u3082\u306b\u4f53\u8102\u80aa\u304c\u5897\u52a0\u3057\u3084\u3059\u304f\u306a\u308b\u304b\u3069\u3046\u304b\u304c\u5de6\u53f3\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u52a0\u9f62\u306b\u4f34\u3063\u3066\u5206\u6ccc\u304c\u4f4e\u4e0b\u3059\u308b<strong>\u6210\u9577\u30db\u30eb\u30e2\u30f3\uff08GH\uff09\u3084DHEA<\/strong>\u306a\u3069\u306e\u30db\u30eb\u30e2\u30f3\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u3082\u3001\u907a\u4f1d\u7684\u306b\u6c7a\u307e\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u3053\u308c\u304c\u7b4b\u8089\u91cf\u3084\u8102\u80aa\u84c4\u7a4d\u306b\u5f71\u97ff\u3057\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u52a0\u9f62\u3068\u907a\u4f1d\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u306f\u3001\u5e74\u9f62\u306b\u5fdc\u3058\u305f\u6700\u9069\u306a\u4f53\u578b\u7ba1\u7406\u3001\u6804\u990a\u6226\u7565\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5\u306e\u8a2d\u8a08\u306b\u5f79\u7acb\u3064\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div 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