{"id":1273,"date":"2025-01-03T03:04:05","date_gmt":"2025-01-03T03:04:05","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=1273"},"modified":"2025-01-24T02:32:25","modified_gmt":"2025-01-24T02:32:25","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e3%81%8c%e3%82%93%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e6%97%a9%e6%9c%9f%e7%99%ba%e8%a6%8b%e3%81%ae%e9%8d%b5%e3%82%92%e6%8e%a2%e3%82%8b","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e3%81%8c%e3%82%93%e3%83%aa%e3%82%b9%e3%82%af%ef%bc%9a%e6%97%a9%e6%9c%9f%e7%99%ba%e8%a6%8b%e3%81%ae%e9%8d%b5%e3%82%92%e6%8e%a2%e3%82%8b\/","title":{"rendered":"\u907a\u4f1d\u5b50\u3068\u304c\u3093\u30ea\u30b9\u30af\uff1a\u65e9\u671f\u767a\u898b\u306e\u9375\u3092\u63a2\u308b"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u304c\u3093\u30ea\u30b9\u30af\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u304c\u3093\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u7684\u8981\u56e0\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u767a\u75c7\u3057\u307e\u3059\u3002\u907a\u4f1d\u5b50\u306f\u3001\u7d30\u80de\u306e\u6b63\u5e38\u306a\u5206\u88c2\u3084\u4fee\u5fa9\u3092\u5236\u5fa1\u3059\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u907a\u4f1d\u5b50\u306e\u7570\u5e38\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u304c\u3093\u306e\u65e9\u671f\u767a\u898b\u3084\u4e88\u9632\u7b56\u306e\u7b56\u5b9a\u306b\u7e4b\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306f\u3001\u304c\u3093\u306e\u767a\u751f\u306b\u76f4\u63a5\u5f71\u97ff\u3092\u53ca\u307c\u3059<strong>\u816b\u760d\u6291\u5236\u907a\u4f1d\u5b50<\/strong>\u3084<strong>\u304c\u3093\u539f\u907a\u4f1d\u5b50<\/strong>\u3001DNA\u4fee\u5fa9\u306b\u95a2\u308f\u308b<strong>\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50<\/strong>\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u7a2e\u985e\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3084\u7570\u5e38\u304c\u3001\u304c\u3093\u7d30\u80de\u306e\u5897\u6b96\u3084\u62e1\u6563\u306e\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u816b\u760d\u6291\u5236\u907a\u4f1d\u5b50\u306e\u5f79\u5272<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>BRCA1\/BRCA2\u907a\u4f1d\u5b50\u3068\u4e73\u304c\u3093\u30fb\u5375\u5de3\u304c\u3093<\/strong><\/h3>\n\n\n\n<p>BRCA1\u304a\u3088\u3073BRCA2\u907a\u4f1d\u5b50\u306f\u3001\u304c\u3093\u30ea\u30b9\u30af\u306b\u95a2\u3059\u308b\u6700\u3082\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u308b\u816b\u760d\u6291\u5236\u907a\u4f1d\u5b50\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306f\u3001DNA\u306e\u640d\u50b7\u3092\u4fee\u5fa9\u3057\u3001\u7d30\u80de\u306e\u6b63\u5e38\u306a\u6210\u9577\u3092\u7dad\u6301\u3059\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u751f\u3058\u308b\u3068\u3001DNA\u4fee\u5fa9\u80fd\u529b\u304c\u4f4e\u4e0b\u3057\u3001\u4e73\u304c\u3093\u3084\u5375\u5de3\u304c\u3093\u306e\u30ea\u30b9\u30af\u304c\u5927\u5e45\u306b\u5897\u52a0\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u306b\u3088\u308b\u3068\u3001BRCA1\u307e\u305f\u306fBRCA2\u306b\u5909\u7570\u3092\u6301\u3064\u5973\u6027\u306f\u3001\u4e73\u304c\u3093\u3092\u767a\u75c7\u3059\u308b\u78ba\u7387\u304c60\uff5e80%\u306b\u9054\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.cancer.gov\/\">\u53c2\u8003\uff1aNational Cancer Institute<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>TP53\u907a\u4f1d\u5b50\u3068\u8907\u6570\u306e\u304c\u3093\u30ea\u30b9\u30af<\/strong><\/h3>\n\n\n\n<p>TP53\u907a\u4f1d\u5b50\u306f\u300c\u30b2\u30ce\u30e0\u306e\u5b88\u8b77\u8005\u300d\u3068\u3082\u547c\u3070\u308c\u308b\u91cd\u8981\u306a\u816b\u760d\u6291\u5236\u907a\u4f1d\u5b50\u3067\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306f\u3001\u7d30\u80de\u304cDNA\u640d\u50b7\u3092\u691c\u77e5\u3057\u305f\u969b\u306b\u305d\u306e\u4fee\u5fa9\u3092\u4fc3\u9032\u3057\u3001\u4fee\u5fa9\u304c\u4e0d\u53ef\u80fd\u306a\u5834\u5408\u306b\u306f\u7d30\u80de\u6b7b\uff08\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff09\u3092\u8a98\u5c0e\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u3001TP53\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u591a\u304f\u306e\u304c\u3093\uff08\u4e73\u304c\u3093\u3001\u5927\u8178\u304c\u3093\u3001\u80ba\u304c\u3093\u306a\u3069\uff09\u306b\u304a\u3044\u3066\u4e00\u822c\u7684\u3067\u3042\u308a\u3001\u3053\u306e\u5909\u7570\u304c\u304c\u3093\u306e\u9032\u884c\u3084\u6cbb\u7642\u62b5\u6297\u6027\u306b\u95a2\u9023\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u304c\u3093\u539f\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u5316\u3068\u304c\u3093\u767a\u75c7<\/strong><\/h2>\n\n\n\n<p>\u304c\u3093\u539f\u907a\u4f1d\u5b50\uff08\u30d7\u30ed\u30c8\u30aa\u30f3\u30b3\u30b8\u30fc\u30f3\uff09\u306f\u3001\u6b63\u5e38\u306a\u7d30\u80de\u6210\u9577\u3092\u8abf\u7bc0\u3059\u308b\u907a\u4f1d\u5b50\u3067\u3059\u304c\u3001\u5909\u7570\u3084\u7570\u5e38\u306a\u6d3b\u6027\u5316\u304c\u8d77\u3053\u308b\u3068\u304c\u3093\u539f\u907a\u4f1d\u5b50\u3068\u306a\u308a\u3001\u7d30\u80de\u5897\u6b96\u3092\u5236\u5fa1\u3067\u304d\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>RAS\u907a\u4f1d\u5b50\u3068\u80ba\u304c\u3093\u30fb\u5927\u8178\u304c\u3093<\/strong><\/h3>\n\n\n\n<p>RAS\u907a\u4f1d\u5b50\u306f\u3001\u7d30\u80de\u5206\u88c2\u3084\u5897\u6b96\u3092\u5236\u5fa1\u3059\u308b\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7570\u5e38\u306a\u6d3b\u6027\u5316\u306f\u3001\u80ba\u304c\u3093\u3084\u5927\u8178\u304c\u3093\u3001\u81b5\u81d3\u304c\u3093\u306a\u3069\u3001\u591a\u304f\u306e\u304c\u3093\u3067\u898b\u3089\u308c\u307e\u3059\u3002RAS\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3088\u308a\u3001\u7d30\u80de\u5897\u6b96\u304c\u5236\u5fa1\u4e0d\u80fd\u3068\u306a\u308a\u3001\u304c\u3093\u7d30\u80de\u304c\u5897\u6b96\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>HER2\u907a\u4f1d\u5b50\u3068\u4e73\u304c\u3093<\/strong><\/h3>\n\n\n\n<p>HER2\u907a\u4f1d\u5b50\u306e\u904e\u5270\u767a\u73fe\u306f\u3001\u7279\u306b\u4e73\u304c\u3093\u306b\u304a\u3044\u3066\u554f\u984c\u3068\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u5316\u306f\u3001\u4e73\u304c\u3093\u7d30\u80de\u306e\u5897\u6b96\u3092\u52a0\u901f\u3055\u305b\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u6297\u304c\u3093\u5264\u306b\u5bfe\u3059\u308b\u62b5\u6297\u6027\u3092\u5f15\u304d\u8d77\u3053\u3059\u8981\u56e0\u3068\u3082\u306a\u308a\u307e\u3059\u3002HER2\u967d\u6027\u306e\u4e73\u304c\u3093\u306f\u3001\u5206\u5b50\u6a19\u7684\u6cbb\u7642\u85ac\uff08\u4f8b\uff1a\u30c8\u30e9\u30b9\u30c4\u30ba\u30de\u30d6\uff09\u306b\u3088\u308b\u6cbb\u7642\u304c\u9032\u5316\u3057\u3066\u304a\u308a\u3001\u6cbb\u7642\u6210\u7e3e\u306e\u6539\u5584\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\u3068\u907a\u4f1d\u6027\u304c\u3093\u75c7\u5019\u7fa4<\/strong><\/h2>\n\n\n\n<p>DNA\u306e\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\uff08MMR\uff09\u306f\u3001DNA\u8907\u88fd\u6642\u306e\u30a8\u30e9\u30fc\u3092\u4fee\u5fa9\u3059\u308b\u91cd\u8981\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3059\u3002\u3053\u306e\u4fee\u5fa9\u6a5f\u80fd\u3092\u62c5\u3046\u907a\u4f1d\u5b50\u306e\u7570\u5e38\u306f\u3001\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u5927\u5e45\u306b\u9ad8\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>MLH1\u3001MSH2\u3001MSH6\u907a\u4f1d\u5b50\u3068\u30ea\u30f3\u30c1\u75c7\u5019\u7fa4<\/strong><\/h3>\n\n\n\n<p>\u30ea\u30f3\u30c1\u75c7\u5019\u7fa4\uff08\u907a\u4f1d\u6027\u975e\u30dd\u30ea\u30dd\u30fc\u30b7\u30b9\u5927\u8178\u304c\u3093\uff1aHNPCC\uff09\u306f\u3001\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u907a\u4f1d\u6027\u75be\u60a3\u3067\u3059\u3002\u3053\u306e\u75c7\u5019\u7fa4\u3092\u6301\u3064\u4eba\u306f\u3001\u5927\u8178\u304c\u3093\u3084\u5b50\u5bae\u4f53\u304c\u3093\u3001\u80c3\u304c\u3093\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002\u7279\u306bMLH1\u3084MSH2\u306e\u5909\u7570\u306f\u3001\u5927\u8178\u304c\u3093\u306e\u767a\u75c7\u30ea\u30b9\u30af\u309270%\u4ee5\u4e0a\u306b\u5f15\u304d\u4e0a\u3052\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001\u30ea\u30f3\u30c1\u75c7\u5019\u7fa4\u306e\u30ea\u30b9\u30af\u3092\u65e9\u671f\u306b\u7279\u5b9a\u3057\u3001\u4e88\u9632\u7684\u306a\u5927\u8178\u5185\u8996\u93e1\u691c\u67fb\u3084\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u3092\u884c\u3046\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-64a3b38a-7fff-a1c4-cf66-277de905bc74\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u3068\u304c\u3093\u306e\u65e9\u671f\u767a\u898b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/24513412_m-1024x683.jpg\" alt=\"\" class=\"wp-image-1935\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/24513412_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/24513412_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/24513412_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/24513412_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/24513412_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8fd1\u5e74\u306e\u6280\u8853\u9769\u65b0\u306b\u3088\u308a\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u5229\u7528\u3057\u305f\u304c\u3093\u30ea\u30b9\u30af\u306e\u7279\u5b9a\u3084\u65e9\u671f\u767a\u898b\u304c\u73fe\u5b9f\u306e\u3082\u306e\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u691c\u67fb\u306f\u3001\u30ea\u30b9\u30af\u306e\u3042\u308b\u4eba\u3005\u306b\u5bfe\u3057\u3066\u4e88\u9632\u7b56\u3084\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3092\u63d0\u4f9b\u3059\u308b\u305f\u3081\u306e\u91cd\u8981\u306a\u30c4\u30fc\u30eb\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\u306b\u3088\u308b\u5168\u30b2\u30ce\u30e0\u89e3\u6790<\/strong><\/h3>\n\n\n\n<p>\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\u306f\u3001\u304c\u3093\u95a2\u9023\u907a\u4f1d\u5b50\u3092\u7db2\u7f85\u7684\u306b\u89e3\u6790\u3067\u304d\u308b\u753b\u671f\u7684\u306a\u6280\u8853\u3067\u3059\u3002\u3053\u306e\u65b9\u6cd5\u306b\u3088\u308a\u3001BRCA1\/BRCA2\u3084TP53\u3001RAS\u306a\u3069\u8907\u6570\u306e\u304c\u3093\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u540c\u6642\u306b\u691c\u51fa\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002NGS\u306f\u3001\u304c\u3093\u306e\u500b\u5225\u5316\u533b\u7642\u3092\u63a8\u9032\u3059\u308b\u91cd\u8981\u306a\u57fa\u76e4\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u691c\u67fb\u306e\u5b9f\u4f8b<\/strong><\/h4>\n\n\n\n<p>\u73fe\u5728\u3067\u306f\u3001BRCA\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u53d7\u3051\u308b\u3053\u3068\u3067\u4e73\u304c\u3093\u30fb\u5375\u5de3\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u628a\u63e1\u3057\u3001\u4e88\u9632\u7684\u63aa\u7f6e\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u4e00\u822c\u7684\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u8840\u6db2\u30b5\u30f3\u30d7\u30eb\u3092\u7528\u3044\u305f\u300c\u30ea\u30ad\u30c3\u30c9\u30d0\u30a4\u30aa\u30d7\u30b7\u30fc\u300d\u306f\u3001\u304c\u3093\u95a2\u9023\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u691c\u51fa\u3057\u3001\u65e9\u671f\u767a\u898b\u3084\u6cbb\u7642\u65b9\u91dd\u306e\u6c7a\u5b9a\u306b\u5f79\u7acb\u3066\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u502b\u7406\u7684\u8ab2\u984c<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u5229\u7528\u304c\u5e83\u304c\u308b\u4e00\u65b9\u3067\u3001\u502b\u7406\u7684\u306a\u8ab2\u984c\u3082\u6d6e\u304d\u5f6b\u308a\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u691c\u67fb\u7d50\u679c\u304c\u3082\u305f\u3089\u3059\u5fc3\u7406\u7684\u5f71\u97ff\u3084\u3001\u4fdd\u967a\u3084\u96c7\u7528\u306b\u304a\u3051\u308b\u5dee\u5225\u306e\u30ea\u30b9\u30af\u306b\u3064\u3044\u3066\u306f\u3001\u9069\u5207\u306a\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3068\u500b\u4eba\u60c5\u5831\u4fdd\u8b77\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-64a3b38a-7fff-a1c4-cf66-277de905bc74\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u751f\u6d3b\u7fd2\u6163\u3068\u907a\u4f1d\u5b50\u306e\u76f8\u4e92\u4f5c\u7528<\/strong><\/h2>\n\n\n\n<p>\u304c\u3093\u306f\u907a\u4f1d\u7684\u8981\u56e0\u3060\u3051\u3067\u306a\u304f\u3001\u74b0\u5883\u8981\u56e0\u3084\u751f\u6d3b\u7fd2\u6163\u306e\u5f71\u97ff\u3082\u5927\u304d\u304f\u53d7\u3051\u307e\u3059\u3002\u7279\u5b9a\u306e\u751f\u6d3b\u7fd2\u6163\u304c\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u3084\u304c\u3093\u30ea\u30b9\u30af\u306b\u3069\u306e\u3088\u3046\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u304b\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u304c\u3001\u4e88\u9632\u306e\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u304c\u3093\u30ea\u30b9\u30af<\/strong><\/h3>\n\n\n\n<p>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306f\u3001\u907a\u4f1d\u5b50\u914d\u5217\u305d\u306e\u3082\u306e\u3092\u5909\u3048\u305a\u306b\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u4ed5\u7d44\u307f\u3067\u3059\u3002\u98df\u4e8b\u3084\u55ab\u7159\u3001\u904b\u52d5\u3001\u30b9\u30c8\u30ec\u30b9\u306a\u3069\u306e\u74b0\u5883\u8981\u56e0\u306f\u3001DNA\u30e1\u30c1\u30eb\u5316\u3084\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u3092\u901a\u3058\u3066\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u3092\u5909\u5316\u3055\u305b\u3001\u304c\u3093\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u5897\u52a0\u307e\u305f\u306f\u6e1b\u5c11\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u98df\u4e8b\u3068\u304c\u3093\u30ea\u30b9\u30af\u306e\u8abf\u6574<\/strong><\/h4>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u8449\u9178\u3084\u30d3\u30bf\u30df\u30f3D\u3092\u591a\u304f\u542b\u3080\u98df\u54c1\u306f\u3001DNA\u4fee\u5fa9\u3084\u30e1\u30c1\u30eb\u5316\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u3053\u3068\u3067\u304c\u3093\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u52b9\u679c\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u3084\u52a0\u5de5\u8089\u306e\u904e\u5270\u6442\u53d6\u306f\u3001\u907a\u4f1d\u5b50\u5909\u7570\u3084\u708e\u75c7\u3092\u4fc3\u9032\u3057\u3001\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u8981\u56e0\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-64a3b38a-7fff-a1c4-cf66-277de905bc74\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u304c\u3093\u306e\u500b\u5225\u5316\u533b\u7642<\/strong><\/h2>\n\n\n\n<p>\u304c\u3093\u7814\u7a76\u306b\u304a\u3051\u308b\u907a\u4f1d\u5b50\u89e3\u6790\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u500b\u5225\u5316\u533b\u7642\uff08\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30e1\u30c7\u30a3\u30b7\u30f3\uff09\u304c\u5927\u304d\u304f\u9032\u5316\u3057\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u57fa\u306b\u3001\u304c\u3093\u60a3\u8005\u4e00\u4eba\u3072\u3068\u308a\u306b\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u3092\u63d0\u4f9b\u3059\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u5f93\u6765\u306e\u753b\u4e00\u7684\u306a\u6cbb\u7642\u3092\u8d85\u3048\u3001\u6cbb\u7642\u52b9\u679c\u306e\u5411\u4e0a\u3068\u526f\u4f5c\u7528\u306e\u8efd\u6e1b\u306b\u8ca2\u732e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u5206\u5b50\u6a19\u7684\u6cbb\u7642\u306e\u9032\u5316<\/strong><\/h3>\n\n\n\n<p>\u5206\u5b50\u6a19\u7684\u6cbb\u7642\u85ac\u306f\u3001\u304c\u3093\u7d30\u80de\u306b\u7279\u6709\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3084\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u3059\u308b\u6cbb\u7642\u6cd5\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001HER2\u907a\u4f1d\u5b50\u306e\u904e\u5270\u767a\u73fe\u304c\u898b\u3089\u308c\u308b\u4e73\u304c\u3093\u306b\u306f\u3001HER2\u3092\u6a19\u7684\u3068\u3057\u305f\u85ac\u5264\uff08\u4f8b\uff1a\u30c8\u30e9\u30b9\u30c4\u30ba\u30de\u30d6\uff09\u304c\u9ad8\u3044\u6cbb\u7642\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002\u307e\u305f\u3001EGFR\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u80ba\u304c\u3093\u3067\u306f\u3001EGFR\u963b\u5bb3\u5264\uff08\u4f8b\uff1a\u30b2\u30d5\u30a3\u30c1\u30cb\u30d6\uff09\u304c\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306a\u5206\u5b50\u6a19\u7684\u6cbb\u7642\u306f\u3001\u304c\u3093\u306e\u7a2e\u985e\u3084\u907a\u4f1d\u5b50\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u57fa\u3065\u3044\u3066\u9069\u5fdc\u304c\u5224\u65ad\u3055\u308c\u308b\u305f\u3081\u3001\u4e8b\u524d\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u52b9\u679c\u7684\u306a\u6cbb\u7642\u6cd5\u306e\u9078\u629e\u304c\u53ef\u80fd\u3068\u306a\u308a\u3001\u6cbb\u7642\u306e\u6210\u529f\u7387\u304c\u5411\u4e0a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u4f8b<\/strong><\/h4>\n\n\n\n<p>2020\u5e74\u306b\u767a\u8868\u3055\u308c\u305f\u7814\u7a76\u3067\u306f\u3001\u80ba\u304c\u3093\u60a3\u8005\u306e\u907a\u4f1d\u5b50\u89e3\u6790\u3092\u57fa\u306b\u6cbb\u7642\u6cd5\u3092\u9078\u629e\u3057\u305f\u7d50\u679c\u3001\u5168\u4f53\u751f\u5b58\u7387\u304c\u7d0420%\u5411\u4e0a\u3057\u305f\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\uff08<a href=\"https:\/\/www.thelancet.com\/\">\u53c2\u8003\uff1aThe Lancet Oncology<\/a>\uff09\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u304c\u3093\u4e88\u9632\u6226\u7565<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"765\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/30764222_m-1024x765.jpg\" alt=\"\u751f\u6d3b\u7fd2\u6163\u75c5\" class=\"wp-image-1687\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30764222_m-1024x765.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30764222_m-300x224.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30764222_m-768x574.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30764222_m-1536x1147.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30764222_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u304c\u3093\u306e\u4e88\u9632\u6226\u7565\u3082\u91cd\u8981\u306a\u5206\u91ce\u3067\u3059\u3002\u304c\u3093\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u907a\u4f1d\u5b50\u5909\u7570\u304c\u7279\u5b9a\u3055\u308c\u308b\u3053\u3068\u3067\u3001\u751f\u6d3b\u7fd2\u6163\u3084\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306e\u6539\u5584\u3092\u901a\u3058\u3066\u3001\u304c\u3093\u306e\u767a\u75c7\u3092\u672a\u7136\u306b\u9632\u3050\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u53ef\u80fd\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u4e88\u9632\u7684\u5916\u79d1\u624b\u8853<\/strong><\/h3>\n\n\n\n<p>BRCA1\/BRCA2\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u7279\u5b9a\u3055\u308c\u305f\u5834\u5408\u3001\u4e73\u623f\u3084\u5375\u5de3\u306e\u4e88\u9632\u7684\u5207\u9664\u304c\u63a8\u5968\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30cf\u30ea\u30a6\u30c3\u30c9\u5973\u512a\u30a2\u30f3\u30b8\u30a7\u30ea\u30fc\u30ca\u30fb\u30b8\u30e7\u30ea\u30fc\u304c\u884c\u3063\u305f\u4e88\u9632\u7684\u4e73\u623f\u5207\u9664\u306f\u3001\u304c\u3093\u4e88\u9632\u306e\u4e00\u4f8b\u3068\u3057\u3066\u5e83\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u624b\u8853\u306f\u3001\u4e73\u304c\u3093\u30ea\u30b9\u30af\u309290%\u4ee5\u4e0a\u4f4e\u6e1b\u3055\u305b\u308b\u52b9\u679c\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306e\u5f37\u5316<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3067\u304c\u3093\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u304c\u5224\u660e\u3057\u305f\u5834\u5408\u3001\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u691c\u67fb\u306e\u983b\u5ea6\u3092\u9ad8\u3081\u308b\u3053\u3068\u3067\u3001\u65e9\u671f\u767a\u898b\u306e\u53ef\u80fd\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30ea\u30f3\u30c1\u75c7\u5019\u7fa4\u3092\u6301\u3064\u4eba\u306f\u5b9a\u671f\u7684\u306a\u5927\u8178\u5185\u8996\u93e1\u691c\u67fb\u3092\u53d7\u3051\u308b\u3053\u3068\u3067\u3001\u5927\u8178\u304c\u3093\u306e\u65e9\u671f\u767a\u898b\u3084\u4e88\u9632\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u304c\u3093\u3068\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306e\u5f79\u5272<\/strong><\/h2>\n\n\n\n<p>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306f\u3001\u907a\u4f1d\u5b50\u305d\u306e\u3082\u306e\u3092\u5909\u3048\u305a\u306b\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3059\u308b\u4ed5\u7d44\u307f\u3092\u6307\u3057\u307e\u3059\u3002\u8fd1\u5e74\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u304c\u3093\u306e\u95a2\u4fc2\u304c\u6ce8\u76ee\u3055\u308c\u3066\u304a\u308a\u3001\u3053\u306e\u5206\u91ce\u306e\u7814\u7a76\u306f\u3001\u304c\u3093\u306e\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u306b\u5bc4\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>DNA\u30e1\u30c1\u30eb\u5316\u3068\u304c\u3093<\/strong><\/h3>\n\n\n\n<p>DNA\u30e1\u30c1\u30eb\u5316\u306f\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306e\u4e3b\u8981\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u3064\u3067\u3042\u308a\u3001\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u6291\u5236\u3057\u307e\u3059\u3002\u816b\u760d\u6291\u5236\u907a\u4f1d\u5b50\u306eDNA\u30e1\u30c1\u30eb\u5316\u304c\u904e\u5270\u306b\u9032\u3080\u3068\u3001\u305d\u306e\u907a\u4f1d\u5b50\u304c\u6291\u5236\u3055\u308c\u3001\u304c\u3093\u7d30\u80de\u304c\u5897\u6b96\u3057\u3084\u3059\u304f\u306a\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u6cbb\u7642\u306e\u53ef\u80fd\u6027<\/strong><\/h4>\n\n\n\n<p>DNA\u30e1\u30c1\u30eb\u5316\u3092\u6a19\u7684\u3068\u3059\u308b\u85ac\u5264\uff08\u30c7\u30b7\u30bf\u30d3\u30f3\u3084\u30a2\u30b6\u30b7\u30c1\u30b8\u30f3\u306a\u3069\uff09\u306f\u3001\u7279\u306b\u8840\u6db2\u304c\u3093\u306e\u6cbb\u7642\u306b\u52b9\u679c\u3092\u767a\u63ee\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u85ac\u5264\u306f\u3001DNA\u30e1\u30c1\u30eb\u5316\u306e\u7570\u5e38\u3092\u30ea\u30bb\u30c3\u30c8\u3059\u308b\u3053\u3068\u3067\u3001\u816b\u760d\u6291\u5236\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u3092\u56de\u5fa9\u3055\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u3068\u304c\u3093\u306e\u9032\u884c<\/strong><\/h3>\n\n\n\n<p>\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u3082\u3001\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306e\u4e00\u74b0\u3068\u3057\u3066\u3001\u304c\u3093\u306e\u767a\u75c7\u3084\u9032\u884c\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u30d2\u30b9\u30c8\u30f3\u30a2\u30bb\u30c1\u30eb\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc\uff08HAT\uff09\u3084\u30d2\u30b9\u30c8\u30f3\u30c7\u30a2\u30bb\u30c1\u30e9\u30fc\u30bc\uff08HDAC\uff09\u306e\u7570\u5e38\u306a\u6d3b\u6027\u5316\u306f\u3001\u304c\u3093\u7d30\u80de\u306e\u5897\u6b96\u3092\u52a9\u9577\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>HDAC\u963b\u5bb3\u5264\uff08\u4f8b\uff1a\u30dc\u30ea\u30ce\u30b9\u30bf\u30c3\u30c8\uff09\u306f\u3001\u304c\u3093\u6cbb\u7642\u306e\u65b0\u305f\u306a\u9078\u629e\u80a2\u3068\u3057\u3066\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u7279\u306b\u30ea\u30f3\u30d1\u816b\u3084\u591a\u767a\u6027\u9aa8\u9ac4\u816b\u306e\u6cbb\u7642\u3067\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u7814\u7a76\u3068\u30ea\u30ad\u30c3\u30c9\u30d0\u30a4\u30aa\u30d7\u30b7\u30fc\u306e\u53ef\u80fd\u6027<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/23532594_m-1024x683.jpg\" alt=\"\u63a1\u8840\" class=\"wp-image-2627\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23532594_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23532594_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23532594_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23532594_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23532594_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30ea\u30ad\u30c3\u30c9\u30d0\u30a4\u30aa\u30d7\u30b7\u30fc\u306f\u3001\u8840\u6db2\u3084\u4f53\u6db2\u3092\u7528\u3044\u3066\u304c\u3093\u3092\u691c\u51fa\u3059\u308b\u6280\u8853\u3067\u3042\u308a\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u6210\u679c\u304c\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u65b9\u6cd5\u306f\u3001\u304c\u3093\u306e\u65e9\u671f\u767a\u898b\u3084\u6cbb\u7642\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306b\u304a\u3044\u3066\u753b\u671f\u7684\u306a\u9032\u5c55\u3092\u3082\u305f\u3089\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b5\u30fc\u30ad\u30e5\u30ec\u30fc\u30c6\u30a3\u30f3\u30b0DNA\uff08ctDNA\uff09\u306e\u691c\u51fa<\/strong><\/h3>\n\n\n\n<p>\u304c\u3093\u7d30\u80de\u304c\u6b7b\u6ec5\u3059\u308b\u3068\u3001\u305d\u306e\u65ad\u7247\u3067\u3042\u308b\u30b5\u30fc\u30ad\u30e5\u30ec\u30fc\u30c6\u30a3\u30f3\u30b0DNA\uff08ctDNA\uff09\u304c\u8840\u6db2\u4e2d\u306b\u653e\u51fa\u3055\u308c\u307e\u3059\u3002\u30ea\u30ad\u30c3\u30c9\u30d0\u30a4\u30aa\u30d7\u30b7\u30fc\u3067\u306f\u3001\u3053\u306ectDNA\u3092\u89e3\u6790\u3057\u3001\u304c\u3093\u306b\u7279\u6709\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u7279\u5b9a\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u5fdc\u7528\u4f8b<\/strong><\/h4>\n\n\n\n<p>\u30ea\u30ad\u30c3\u30c9\u30d0\u30a4\u30aa\u30d7\u30b7\u30fc\u306f\u3001\u80ba\u304c\u3093\u3084\u5927\u8178\u304c\u3093\u306e\u907a\u4f1d\u5b50\u5909\u7570\uff08\u4f8b\uff1aEGFR\u3084KRAS\u5909\u7570\uff09\u3092\u691c\u51fa\u3059\u308b\u305f\u3081\u306b\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u304c\u3093\u6cbb\u7642\u306e\u7d4c\u904e\u3092\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u8ffd\u8de1\u3057\u3001\u6cbb\u7642\u52b9\u679c\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306e\u30c4\u30fc\u30eb\u3068\u3057\u3066\u3082\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u5229\u70b9\u3068\u8ab2\u984c<\/strong><\/h3>\n\n\n\n<p>\u30ea\u30ad\u30c3\u30c9\u30d0\u30a4\u30aa\u30d7\u30b7\u30fc\u306e\u5229\u70b9\u306f\u3001\u975e\u4fb5\u8972\u7684\u3067\u3042\u308b\u3053\u3068\u3001\u8fc5\u901f\u306b\u7d50\u679c\u304c\u5f97\u3089\u308c\u308b\u3053\u3068\u3001\u6cbb\u7642\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306b\u5f79\u7acb\u3064\u3053\u3068\u3067\u3059\u3002\u4e00\u65b9\u3067\u3001\u611f\u5ea6\u3084\u7279\u7570\u6027\u306e\u5411\u4e0a\u304c\u8ab2\u984c\u3068\u3057\u3066\u6319\u3052\u3089\u308c\u3066\u304a\u308a\u3001\u6280\u8853\u306e\u3055\u3089\u306a\u308b\u767a\u5c55\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-64a3b38a-7fff-a1c4-cf66-277de905bc74\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u7814\u7a76\u304c\u5207\u308a\u958b\u304f\u304c\u3093\u6cbb\u7642\u306e\u672a\u6765<\/strong><\/h2>\n\n\n\n<p>\u304c\u3093\u306b\u95a2\u3059\u308b\u907a\u4f1d\u5b50\u7814\u7a76\u306f\u3001\u6cbb\u7642\u6cd5\u3084\u4e88\u9632\u7b56\u306e\u958b\u767a\u3092\u52a0\u901f\u3055\u305b\u3001\u304c\u3093\u60a3\u8005\u306e\u751f\u6d3b\u306e\u8cea\uff08QOL\uff09\u5411\u4e0a\u306b\u5bc4\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u500b\u5225\u5316\u533b\u7642\u306e\u5b8c\u5168\u5b9f\u73fe<\/strong><\/h3>\n\n\n\n<p>AI\u3084\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u60a3\u8005\u306e\u907a\u4f1d\u5b50\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u57fa\u3065\u3044\u305f\u6cbb\u7642\u6cd5\u306e\u63d0\u6848\u304c\u307e\u3059\u307e\u3059\u9ad8\u5ea6\u5316\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u304c\u3093\u306e\u6cbb\u7642\u52b9\u679c\u3092\u6700\u5927\u5316\u3057\u3001\u526f\u4f5c\u7528\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u3068\u304c\u3093\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<p>CRISPR-Cas9\u306a\u3069\u306e\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306f\u3001\u304c\u3093\u7d30\u80de\u306e\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3092\u6a19\u7684\u306b\u3057\u3066\u6cbb\u7642\u3092\u884c\u3046\u65b0\u3057\u3044\u65b9\u6cd5\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u304c\u3093\u7d30\u80de\u306e\u5897\u6b96\u3092\u52a9\u3051\u308b\u907a\u4f1d\u5b50\u3092\u7de8\u96c6\u3057\u3066\u6a5f\u80fd\u3092\u505c\u6b62\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u304c\u3093\u306e\u9032\u884c\u3092\u6291\u5236\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-64a3b38a-7fff-a1c4-cf66-277de905bc74\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u514d\u75ab\u7642\u6cd5\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u304c\u3093\u6cbb\u7642\u306e\u4e2d\u3067\u3082\u3001\u514d\u75ab\u7642\u6cd5\u306f\u8fd1\u5e74\u6ce8\u76ee\u3092\u96c6\u3081\u308b\u5206\u91ce\u3067\u3042\u308a\u3001\u305d\u306e\u52b9\u679c\u306b\u306f\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u304c\u6df1\u304f\u95a2\u308f\u3063\u3066\u3044\u307e\u3059\u3002\u514d\u75ab\u7642\u6cd5\u306f\u3001\u4f53\u5185\u306e\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u3092\u6d3b\u6027\u5316\u3055\u305b\u3001\u304c\u3093\u7d30\u80de\u3092\u653b\u6483\u3059\u308b\u65b9\u6cd5\u3067\u3042\u308a\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u304c\u305d\u306e\u6210\u529f\u306e\u9375\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>PD-1\/PD-L1\u3068\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264<\/strong><\/h3>\n\n\n\n<p>\u304c\u3093\u7d30\u80de\u306f\u3001PD-1\uff08\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b1\uff09\u3084PD-L1\uff08\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\u30ea\u30ac\u30f3\u30c91\uff09\u3068\u3044\u3063\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u5229\u7528\u3057\u3066\u514d\u75ab\u7d30\u80de\u306e\u50cd\u304d\u3092\u6291\u5236\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u304c\u3093\u7d30\u80de\u306f\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u306e\u653b\u6483\u3092\u56de\u907f\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<br>\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\uff08\u4f8b\uff1a\u30da\u30f3\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u3001\u30cb\u30dc\u30eb\u30de\u30d6\uff09\u306f\u3001PD-1\/PD-L1\u7d4c\u8def\u3092\u906e\u65ad\u3057\u3001\u514d\u75ab\u7d30\u80de\u304c\u518d\u3073\u304c\u3093\u7d30\u80de\u3092\u653b\u6483\u3067\u304d\u308b\u3088\u3046\u306b\u3059\u308b\u6cbb\u7642\u6cd5\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u91cd\u8981\u6027<\/strong><\/h4>\n\n\n\n<p>PD-L1\u306e\u767a\u73fe\u30ec\u30d9\u30eb\u3084\u3001\u907a\u4f1d\u5b50\u5909\u7570\u306e\u8ca0\u8377\uff08TMB: Tumor Mutational Burden\uff09\u306f\u3001\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\u304c\u6709\u52b9\u304b\u3069\u3046\u304b\u3092\u5224\u65ad\u3059\u308b\u91cd\u8981\u306a\u6307\u6a19\u3068\u306a\u308a\u307e\u3059\u3002\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u901a\u3058\u3066\u3001\u60a3\u8005\u3054\u3068\u306e\u6cbb\u7642\u52b9\u679c\u3092\u4e88\u6e2c\u3059\u308b\u3053\u3068\u3067\u3001\u6cbb\u7642\u306e\u6210\u529f\u7387\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>CAR-T\u7d30\u80de\u7642\u6cd5\u3068\u907a\u4f1d\u5b50\u6539\u5909<\/strong><\/h3>\n\n\n\n<p>CAR-T\u7d30\u80de\u7642\u6cd5\u306f\u3001\u60a3\u8005\u81ea\u8eab\u306eT\u7d30\u80de\u3092\u907a\u4f1d\u5b50\u6539\u5909\u3057\u3066\u304c\u3093\u7d30\u80de\u3092\u653b\u6483\u3059\u308b\u3088\u3046\u30d7\u30ed\u30b0\u30e9\u30e0\u3059\u308b\u6cbb\u7642\u6cd5\u3067\u3059\u3002\u3053\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u7279\u306b\u8840\u6db2\u304c\u3093\uff08\u6025\u6027\u30ea\u30f3\u30d1\u6027\u767d\u8840\u75c5\u3084\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\uff09\u306b\u304a\u3044\u3066\u9ad8\u3044\u6cbb\u7642\u52b9\u679c\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u5177\u4f53\u7684\u306a\u4ed5\u7d44\u307f<\/strong><\/h4>\n\n\n\n<p>T\u7d30\u80de\u306bCAR\uff08\u30ad\u30e1\u30e9\u6297\u539f\u53d7\u5bb9\u4f53\uff09\u3068\u547c\u3070\u308c\u308b\u4eba\u5de5\u7684\u306a\u53d7\u5bb9\u4f53\u3092\u5c0e\u5165\u3057\u3001\u304c\u3093\u7d30\u80de\u7279\u6709\u306e\u6297\u539f\u3092\u8a8d\u8b58\u3057\u3066\u653b\u6483\u3059\u308b\u3088\u3046\u306b\u6539\u5909\u3057\u307e\u3059\u3002\u3053\u306e\u6cbb\u7642\u6cd5\u306f\u3001\u500b\u5225\u5316\u3055\u308c\u305f\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u5fc5\u8981\u3067\u3042\u308a\u3001\u60a3\u8005\u306e\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u57fa\u306b\u6cbb\u7642\u304c\u8a2d\u8a08\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u304c\u3093\u306e\u8ee2\u79fb\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"771\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/30630181_m-1024x771.jpg\" alt=\"\" class=\"wp-image-1356\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30630181_m-1024x771.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30630181_m-300x226.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30630181_m-768x578.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30630181_m-1536x1157.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/30630181_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u304c\u3093\u306e\u8ee2\u79fb\u306f\u3001\u304c\u3093\u6cbb\u7642\u306b\u304a\u3051\u308b\u6700\u5927\u306e\u8ab2\u984c\u306e\u4e00\u3064\u3067\u3059\u3002\u8ee2\u79fb\u306e\u904e\u7a0b\u306b\u306f\u8907\u6570\u306e\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>EMT\u3068\u8ee2\u79fb\u4fc3\u9032\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>EMT\uff08\u4e0a\u76ae\u9593\u8449\u8ee2\u63db\uff09\u306f\u3001\u304c\u3093\u7d30\u80de\u304c\u8ee2\u79fb\u80fd\u529b\u3092\u7372\u5f97\u3059\u308b\u30d7\u30ed\u30bb\u30b9\u3067\u3042\u308a\u3001\u3053\u306e\u904e\u7a0b\u3092\u5236\u5fa1\u3059\u308b\u907a\u4f1d\u5b50\u304c\u7279\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001SNAIL\u3084TWIST\u3068\u3044\u3063\u305f\u8ee2\u5199\u56e0\u5b50\u304cEMT\u3092\u4fc3\u9032\u3057\u3001\u304c\u3093\u7d30\u80de\u304c\u5468\u56f2\u306e\u7d44\u7e54\u306b\u6d78\u6f64\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u4f8b<\/strong><\/h4>\n\n\n\n<p>SNAIL\u3084TWIST\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3001\u304c\u3093\u7d30\u80de\u306e\u8ee2\u79fb\u80fd\u529b\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u6cbb\u7642\u6cd5\u304c\u52d5\u7269\u30e2\u30c7\u30eb\u3067\u691c\u8a3c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u7814\u7a76\u306f\u3001\u8ee2\u79fb\u3092\u9632\u3050\u65b0\u3057\u3044\u85ac\u5264\u306e\u958b\u767a\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u5909\u7570\u3068\u9060\u9694\u8ee2\u79fb\u306e\u30ea\u30b9\u30af<\/strong><\/h3>\n\n\n\n<p>\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u306f\u3001\u304c\u3093\u7d30\u80de\u304c\u8840\u6d41\u3084\u30ea\u30f3\u30d1\u6db2\u3092\u901a\u3058\u3066\u4ed6\u306e\u81d3\u5668\u306b\u8ee2\u79fb\u3059\u308b\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001KRAS\u3084PIK3CA\u3068\u3044\u3063\u305f\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u80ba\u3084\u809d\u81d3\u3078\u306e\u8ee2\u79fb\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002<br>\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u305f\u5206\u5b50\u6a19\u7684\u6cbb\u7642\u85ac\u306e\u958b\u767a\u304c\u9032\u3093\u3067\u304a\u308a\u3001\u8ee2\u79fb\u6027\u304c\u3093\u306e\u6cbb\u7642\u6210\u7e3e\u5411\u4e0a\u306b\u5bc4\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u304c\u3093\u3068\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u306e\u907a\u4f1d\u7684\u95a2\u9023<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u8178\u5185\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\uff08\u8178\u5185\u7d30\u83cc\u53e2\uff09\u304c\u304c\u3093\u306e\u767a\u751f\u3084\u6cbb\u7642\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u3068\u907a\u4f1d\u5b50\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u65b0\u3057\u3044\u4e88\u9632\u6cd5\u3084\u6cbb\u7642\u6cd5\u306e\u53ef\u80fd\u6027\u304c\u5e83\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u8178\u5185\u7d30\u83cc\u3068\u304c\u3093\u306e\u30ea\u30b9\u30af<\/strong><\/h3>\n\n\n\n<p>\u7279\u5b9a\u306e\u8178\u5185\u7d30\u83cc\u304c\u3001\u304c\u3093\u306e\u767a\u751f\u30ea\u30b9\u30af\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>Fusobacterium nucleatum<\/strong>\u306f\u3001\u5927\u8178\u304c\u3093\u306e\u9032\u884c\u3092\u52a9\u9577\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u7d30\u83cc\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3068\u3057\u3066\u77e5\u3089\u308c\u308b\u4e73\u9178\u83cc\u3084\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\u306f\u3001\u8178\u5185\u74b0\u5883\u3092\u6539\u5584\u3057\u3001\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u306e\u95a2\u9023<\/strong><\/h4>\n\n\n\n<p>\u907a\u4f1d\u5b50\u5909\u7570\u304c\u8178\u5185\u74b0\u5883\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001APC\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u5927\u8178\u304c\u3093\u306e\u767a\u751f\u3060\u3051\u3067\u306a\u304f\u3001\u8178\u5185\u7d30\u83cc\u306e\u30d0\u30e9\u30f3\u30b9\u306e\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u76f8\u4e92\u4f5c\u7528\u3092\u8abf\u6574\u3059\u308b\u3053\u3068\u3067\u3001\u304c\u3093\u4e88\u9632\u306e\u65b0\u305f\u306a\u624b\u6bb5\u304c\u63d0\u4f9b\u3055\u308c\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-64a3b38a-7fff-a1c4-cf66-277de905bc74\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u304c\u3093\u7814\u7a76\u306e\u672a\u6765\u3068\u6280\u8853\u9769\u65b0<\/strong><\/h2>\n\n\n\n<p>\u304c\u3093\u6cbb\u7642\u3068\u4e88\u9632\u306e\u305f\u3081\u306e\u6280\u8853\u306f\u3001\u6025\u901f\u306b\u9032\u5316\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306bAI\u3084\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u3001\u30ca\u30ce\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306e\u9032\u5c55\u304c\u3001\u304c\u3093\u7814\u7a76\u306e\u6b21\u306e\u6bb5\u968e\u3092\u5207\u308a\u958b\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>AI\u306b\u3088\u308b\u304c\u3093\u8a3a\u65ad\u3068\u4e88\u6e2c<\/strong><\/h3>\n\n\n\n<p>\u4eba\u5de5\u77e5\u80fd\uff08AI\uff09\u306f\u3001\u304c\u3093\u8a3a\u65ad\u3084\u6cbb\u7642\u4e88\u6e2c\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002AI\u306f\u3001\u81a8\u5927\u306a\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3084\u60a3\u8005\u306e\u533b\u7642\u8a18\u9332\u3092\u89e3\u6790\u3057\u3001\u304c\u3093\u30ea\u30b9\u30af\u306e\u8a55\u4fa1\u3084\u6cbb\u7642\u306e\u9078\u629e\u80a2\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u5fdc\u7528\u4f8b<\/strong><\/h4>\n\n\n\n<p>AI\u3092\u6d3b\u7528\u3057\u305f\u753b\u50cf\u89e3\u6790\u6280\u8853\u306b\u3088\u308a\u3001\u304c\u3093\u7d30\u80de\u306e\u65e9\u671f\u691c\u51fa\u304c\u53ef\u80fd\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u4e73\u623fX\u7dda\u5199\u771f\u3084\u5185\u8996\u93e1\u753b\u50cf\u3092AI\u304c\u89e3\u6790\u3057\u3001\u304c\u3093\u306e\u5146\u5019\u3092\u4eba\u9593\u306e\u533b\u5e2b\u3088\u308a\u3082\u9ad8\u7cbe\u5ea6\u306b\u767a\u898b\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30ca\u30ce\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u3068\u304c\u3093\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<p>\u30ca\u30ce\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306f\u3001\u304c\u3093\u6cbb\u7642\u306e\u65b0\u305f\u306a\u53ef\u80fd\u6027\u3092\u958b\u304f\u6280\u8853\u3067\u3059\u3002\u7279\u306b\u3001\u30ca\u30ce\u7c92\u5b50\u3092\u5229\u7528\u3057\u3066\u85ac\u5264\u3092\u76f4\u63a5\u304c\u3093\u7d30\u80de\u306b\u9001\u9054\u3059\u308b\u65b9\u6cd5\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6280\u8853\u306f\u3001\u6b63\u5e38\u306a\u7d30\u80de\u3078\u306e\u30c0\u30e1\u30fc\u30b8\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u306a\u304c\u3089\u3001\u304c\u3093\u7d30\u80de\u3092\u52b9\u7387\u7684\u306b\u7834\u58ca\u3059\u308b\u3053\u3068\u3092\u53ef\u80fd\u306b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u793e\u4f1a\u7684\u53d6\u308a\u7d44\u307f<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/31283116_m-1024x683.jpg\" alt=\"\u6559\u80b2\" class=\"wp-image-2634\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31283116_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31283116_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31283116_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31283116_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31283116_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u4f34\u3044\u3001\u304c\u3093\u4e88\u9632\u3084\u6cbb\u7642\u306e\u666e\u53ca\u3092\u76ee\u7684\u3068\u3057\u305f\u793e\u4f1a\u7684\u306a\u53d6\u308a\u7d44\u307f\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u306f\u3001\u6559\u80b2\u3084\u653f\u7b56\u3001\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u30d9\u30fc\u30b9\u306e\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u542b\u307e\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u516c\u8846\u885b\u751f\u3078\u306e\u8ca2\u732e<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u666e\u53ca\u306b\u3088\u308a\u3001\u4e00\u822c\u5e02\u6c11\u304c\u81ea\u8eab\u306e\u304c\u3093\u30ea\u30b9\u30af\u3092\u628a\u63e1\u3057\u3001\u65e9\u671f\u306e\u4e88\u9632\u7b56\u3092\u8b1b\u3058\u308b\u6a5f\u4f1a\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002\u516c\u8846\u885b\u751f\u30ad\u30e3\u30f3\u30da\u30fc\u30f3\u3067\u306f\u3001BRCA\u907a\u4f1d\u5b50\u691c\u67fb\u3084\u304c\u3093\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306e\u91cd\u8981\u6027\u304c\u5f37\u8abf\u3055\u308c\u3001\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u4eba\u3005\u304c\u9069\u5207\u306a\u60c5\u5831\u3092\u5f97\u3089\u308c\u308b\u3088\u3046\u652f\u63f4\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u502b\u7406\u7684\u8ab2\u984c\u3068\u6559\u80b2\u306e\u91cd\u8981\u6027<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u6d3b\u7528\u306b\u306f\u3001\u502b\u7406\u7684\u306a\u554f\u984c\u304c\u4f34\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306e\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u4fdd\u8b77\u3084\u5dee\u5225\u9632\u6b62\u306e\u305f\u3081\u306e\u653f\u7b56\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u540c\u6642\u306b\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u6210\u679c\u3092\u6b63\u3057\u304f\u7406\u89e3\u3057\u3001\u9069\u5207\u306b\u5229\u7528\u3059\u308b\u305f\u3081\u306e\u6559\u80b2\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 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