{"id":1277,"date":"2025-01-03T03:11:41","date_gmt":"2025-01-03T03:11:41","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=1277"},"modified":"2025-01-24T02:45:05","modified_gmt":"2025-01-24T02:45:05","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e8%a8%98%e6%86%b6%e5%8a%9b%e3%81%ae%e9%96%a2%e4%bf%82%ef%bc%9a%e7%a7%91%e5%ad%a6%e3%81%8c%e7%a4%ba%e3%81%99%e6%84%8f%e5%a4%96%e3%81%aa%e4%ba%8b%e5%ae%9f","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e8%a8%98%e6%86%b6%e5%8a%9b%e3%81%ae%e9%96%a2%e4%bf%82%ef%bc%9a%e7%a7%91%e5%ad%a6%e3%81%8c%e7%a4%ba%e3%81%99%e6%84%8f%e5%a4%96%e3%81%aa%e4%ba%8b%e5%ae%9f\/","title":{"rendered":"\u907a\u4f1d\u5b50\u3068\u8a18\u61b6\u529b\u306e\u95a2\u4fc2\uff1a\u79d1\u5b66\u304c\u793a\u3059\u610f\u5916\u306a\u4e8b\u5b9f"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u304c\u8a18\u61b6\u529b\u306b\u4e0e\u3048\u308b\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u306f\u3001\u5b66\u7fd2\u80fd\u529b\u3084\u65e5\u5e38\u751f\u6d3b\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u5de6\u53f3\u3059\u308b\u91cd\u8981\u306a\u8a8d\u77e5\u6a5f\u80fd\u3067\u3059\u3002\u3053\u306e\u80fd\u529b\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u500b\u4eba\u5dee\u306e\u4e00\u56e0\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u8a18\u61b6\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u907a\u4f1d\u5b50\u306f\u6570\u591a\u304f\u5b58\u5728\u3057\u3001\u305d\u308c\u3089\u304c\u795e\u7d4c\u4f1d\u9054\u3001\u30b7\u30ca\u30d7\u30b9\u5f62\u6210\u3001\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u7dad\u6301\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8a18\u61b6\u306b\u306f\u3001\u77ed\u671f\u8a18\u61b6\u3001\u9577\u671f\u8a18\u61b6\u3001\u4f5c\u696d\u8a18\u61b6\u306e3\u3064\u306e\u4e3b\u8981\u306a\u30bf\u30a4\u30d7\u304c\u3042\u308a\u307e\u3059\u3002\u907a\u4f1d\u5b50\u306f\u3053\u308c\u3089\u3059\u3079\u3066\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u8a18\u61b6\u529b\u306e\u5411\u4e0a\u307e\u305f\u306f\u4f4e\u4e0b\u306b\u7e4b\u304c\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u529b\u306b\u95a2\u9023\u3059\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u907a\u4f1d\u5b50\u306b\u306f\u3001\u7279\u5b9a\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3084\u8133\u306e\u69cb\u9020\u5f62\u6210\u306b\u95a2\u4e0e\u3059\u308b\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>BDNF\u907a\u4f1d\u5b50\u3068\u8a18\u61b6\u529b<\/strong><\/h3>\n\n\n\n<p>BDNF\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09\u907a\u4f1d\u5b50\u306f\u3001\u795e\u7d4c\u7d30\u80de\u306e\u6210\u9577\u3084\u30b7\u30ca\u30d7\u30b9\u306e\u53ef\u5851\u6027\u3092\u8abf\u7bc0\u3059\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570\uff08\u4f8b\uff1aVal66Met\u591a\u578b\uff09\u306f\u3001\u8a18\u61b6\u529b\u3084\u5b66\u7fd2\u80fd\u529b\u306b\u76f4\u63a5\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<p>2010\u5e74\u306b\u767a\u8868\u3055\u308c\u305f\u7814\u7a76\u3067\u306f\u3001BDNF\u907a\u4f1d\u5b50\u306bVal66Met\u5909\u7570\u3092\u6301\u3064\u500b\u4eba\u306f\u3001\u30a8\u30d4\u30bd\u30fc\u30c9\u8a18\u61b6\uff08\u7279\u5b9a\u306e\u51fa\u6765\u4e8b\u3092\u601d\u3044\u51fa\u3059\u80fd\u529b\uff09\u304c\u4f4e\u4e0b\u3059\u308b\u50be\u5411\u304c\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\uff08<a href=\"https:\/\/www.nature.com\/articles\/nn.2516\">\u53c2\u8003\uff1aNature Neuroscience<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>APOE\u907a\u4f1d\u5b50\u3068\u8a8d\u77e5\u6a5f\u80fd<\/strong><\/h3>\n\n\n\n<p>APOE\uff08\u30a2\u30dd\u30ea\u30dd\u30bf\u30f3\u30d1\u30afE\uff09\u907a\u4f1d\u5b50\u306f\u3001\u4e3b\u306b\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8f38\u9001\u3084\u8102\u8cea\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u8a18\u61b6\u529b\u3084\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3068\u306e\u95a2\u9023\u6027\u3082\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306bAPOE\u306e\u03b54\u30a2\u30ec\u30eb\u306f\u3001\u8a18\u61b6\u529b\u306e\u4f4e\u4e0b\u3084\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306e\u5897\u52a0\u3068\u95a2\u9023\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001APOE\u306e\u03b52\u30a2\u30ec\u30eb\u306f\u8a18\u61b6\u529b\u3092\u4fdd\u8b77\u3059\u308b\u52b9\u679c\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<p>\u3042\u308b\u7814\u7a76\u3067\u306f\u3001APOE-\u03b54\u3092\u6301\u3064\u9ad8\u9f62\u8005\u304c\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3092\u793a\u3059\u78ba\u7387\u304c\u3001\u305d\u306e\u4ed6\u306e\u30a2\u30ec\u30eb\u3092\u6301\u3064\u500b\u4eba\u3088\u308a\u3082\u7d042\u500d\u9ad8\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.jneurosci.org\/\">\u53c2\u8003\uff1aThe Journal of Neuroscience<\/a>\uff09\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-07ca3791-7fff-5b7b-a5de-7eb0a4cac5b8\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30b7\u30ca\u30d7\u30b9\u53ef\u5851\u6027\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u306e\u5411\u4e0a\u3084\u7dad\u6301\u306b\u306f\u3001\u30b7\u30ca\u30d7\u30b9\u53ef\u5851\u6027\uff08\u30b7\u30ca\u30d7\u30b9\u306e\u5f37\u5ea6\u304c\u5909\u5316\u3059\u308b\u80fd\u529b\uff09\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u3001\u5b66\u7fd2\u3084\u8a18\u61b6\u306e\u57fa\u76e4\u3067\u3042\u308a\u3001\u591a\u304f\u306e\u907a\u4f1d\u5b50\u304c\u305d\u306e\u5236\u5fa1\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>GRIN2B\u907a\u4f1d\u5b50\u3068\u9577\u671f\u5897\u5f37<\/strong><\/h3>\n\n\n\n<p>GRIN2B\u907a\u4f1d\u5b50\u306f\u3001NMDA\u53d7\u5bb9\u4f53\u306e\u4e00\u90e8\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u53d7\u5bb9\u4f53\u306f\u3001\u30b7\u30ca\u30d7\u30b9\u306e\u9577\u671f\u5897\u5f37\uff08LTP\uff1a\u5b66\u7fd2\u3084\u8a18\u61b6\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\uff09\u3092\u4fc3\u9032\u3057\u3001\u65b0\u3057\u3044\u60c5\u5831\u306e\u7372\u5f97\u3092\u52a9\u3051\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u5b66\u7fd2\u80fd\u529b\u3084\u8a18\u61b6\u306e\u5f62\u6210\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u4f8b<\/strong><\/h4>\n\n\n\n<p>\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u7814\u7a76\u3067\u306f\u3001GRIN2B\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u91cf\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u5b66\u7fd2\u80fd\u529b\u3068\u8a18\u61b6\u529b\u304c\u8457\u3057\u304f\u5411\u4e0a\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u53c2\u8003\uff1aCell Reports\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>COMT\u907a\u4f1d\u5b50\u3068\u4f5c\u696d\u8a18\u61b6<\/strong><\/h3>\n\n\n\n<p>COMT\uff08\u30ab\u30c6\u30b3\u30fc\u30eb-O-\u30e1\u30c1\u30eb\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc\uff09\u907a\u4f1d\u5b50\u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u5206\u89e3\u3092\u8abf\u7bc0\u3059\u308b\u9175\u7d20\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u524d\u982d\u524d\u91ce\u3067\u306e\u30c9\u30fc\u30d1\u30df\u30f3\u6fc3\u5ea6\u306f\u3001\u4f5c\u696d\u8a18\u61b6\u306b\u5f37\u304f\u5f71\u97ff\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306eVal158Met\u591a\u578b\u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u4ee3\u8b1d\u901f\u5ea6\u3092\u5909\u5316\u3055\u305b\u3001\u4f5c\u696d\u8a18\u61b6\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-07ca3791-7fff-5b7b-a5de-7eb0a4cac5b8\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u74b0\u5883\u8981\u56e0\u306e\u76f8\u4e92\u4f5c\u7528<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u3060\u3051\u3067\u306a\u304f\u3001\u74b0\u5883\u7684\u8981\u56e0\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u3082\u5927\u304d\u304f\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002\u3053\u308c\u3092\u300c\u907a\u4f1d\u5b50-\u74b0\u5883\u76f8\u4e92\u4f5c\u7528\u300d\u3068\u547c\u3073\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u5b66\u7fd2\u74b0\u5883\u3068BDNF\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u7814\u7a76\u3067\u306f\u3001BDNF\u907a\u4f1d\u5b50\u306eVal66Met\u5909\u7570\u3092\u6301\u3064\u4eba\u3067\u3082\u3001\u5b66\u7fd2\u74b0\u5883\u3084\u904b\u52d5\u7fd2\u6163\u304c\u8a18\u61b6\u529b\u306b\u30d7\u30e9\u30b9\u306e\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u5b9a\u671f\u7684\u306a\u904b\u52d5\u3084\u8a8d\u77e5\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u3001\u30b7\u30ca\u30d7\u30b9\u53ef\u5851\u6027\u3092\u9ad8\u3081\u3001\u8a18\u61b6\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u4f8b\uff1a\u30a8\u30af\u30b5\u30b5\u30a4\u30ba\u306e\u52b9\u679c<\/strong><\/h4>\n\n\n\n<p>\u3042\u308b\u7814\u7a76\u3067\u306f\u3001\u90313\u56de\u306e\u6709\u9178\u7d20\u904b\u52d5\u30926\u30f6\u6708\u9593\u7d99\u7d9a\u3057\u305f\u30b0\u30eb\u30fc\u30d7\u304c\u3001\u8a18\u61b6\u529b\u306e\u30c6\u30b9\u30c8\u3067\u9855\u8457\u306a\u5411\u4e0a\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u52b9\u679c\u306f\u3001BDNF\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u5316\u3092\u901a\u3058\u3066\u5b9f\u73fe\u3055\u308c\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.pnas.org\/\">\u53c2\u8003\uff1aPNAS<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b9\u30c8\u30ec\u30b9\u3068APOE\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u6162\u6027\u7684\u306a\u30b9\u30c8\u30ec\u30b9\u306f\u3001\u8a18\u61b6\u529b\u3084\u8a8d\u77e5\u6a5f\u80fd\u3092\u640d\u306a\u3046\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u3001APOE-\u03b54\u3092\u6301\u3064\u500b\u4eba\u3067\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u308b\u8a18\u61b6\u529b\u4f4e\u4e0b\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u305f\u3081\u3001\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u306f\u907a\u4f1d\u5b50\u306b\u57fa\u3065\u3044\u305f\u8a18\u61b6\u529b\u7dad\u6301\u306e\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u7de8\u96c6\u3068\u8a18\u61b6\u529b\u5411\u4e0a\u306e\u53ef\u80fd\u6027<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/31499900_m-1024x585.jpg\" alt=\"\u672c\" class=\"wp-image-1753\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31499900_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31499900_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31499900_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31499900_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31499900_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>CRISPR-Cas9\u306a\u3069\u306e\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u8a18\u61b6\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u8b70\u8ad6\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001BDNF\u3084GRIN2B\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u8abf\u6574\u3059\u308b\u3053\u3068\u3067\u3001\u8a18\u61b6\u529b\u3092\u5f37\u5316\u3059\u308b\u3053\u3068\u304c\u5c06\u6765\u7684\u306b\u53ef\u80fd\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u502b\u7406\u7684\u8ab2\u984c\u3068\u6280\u8853\u7684\u5236\u7d04<\/strong><\/h3>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u907a\u4f1d\u5b50\u7de8\u96c6\u3092\u7528\u3044\u305f\u8a18\u61b6\u529b\u5f37\u5316\u306b\u306f\u3001\u502b\u7406\u7684\u306a\u554f\u984c\u304c\u4f34\u3044\u307e\u3059\u3002\u300c\u81ea\u7136\u306a\u80fd\u529b\u300d\u3068\u300c\u4eba\u5de5\u7684\u306a\u80fd\u529b\u300d\u306e\u5883\u754c\u7dda\u3092\u3069\u306e\u3088\u3046\u306b\u8a2d\u5b9a\u3059\u308b\u306e\u304b\u3001\u614e\u91cd\u306a\u8b70\u8ad6\u304c\u5fc5\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u6280\u8853\u7684\u306a\u5b89\u5168\u6027\u3084\u9577\u671f\u7684\u306a\u5f71\u97ff\u306b\u3064\u3044\u3066\u3082\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u8a18\u61b6\u529b\u306e\u500b\u5225\u5dee\uff1a\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u53ef\u80fd\u6027<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50\u304c\u500b\u4eba\u3054\u3068\u306b\u7570\u306a\u308b\u305f\u3081\u3001\u305d\u308c\u305e\u308c\u306e\u7279\u6027\u306b\u5fdc\u3058\u305f\u5b66\u7fd2\u6cd5\u3084\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u304c\u52b9\u679c\u7684\u3067\u3059\u3002\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306f\u3001\u8a18\u61b6\u529b\u306b\u57fa\u3065\u3044\u305f\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u53ef\u80fd\u6027\u3092\u5207\u308a\u958b\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u8a18\u61b6\u529b\u5f37\u5316\u6cd5<\/strong><\/h3>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001BDNF\u907a\u4f1d\u5b50\u306eVal66Met\u591a\u578b\u3092\u6301\u3064\u500b\u4eba\u306e\u5834\u5408\u3001\u8a18\u61b6\u529b\u3092\u5f37\u5316\u3059\u308b\u305f\u3081\u306b\u7279\u5b9a\u306e\u74b0\u5883\u8981\u56e0\u3084\u523a\u6fc0\u304c\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u6709\u9178\u7d20\u904b\u52d5\u3084\u7279\u5b9a\u306e\u8a8d\u77e5\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u3001\u3053\u306e\u907a\u4f1d\u5b50\u591a\u578b\u3092\u6301\u3064\u4eba\u3005\u306b\u304a\u3044\u3066\u3001\u8a18\u61b6\u529b\u306e\u5411\u4e0a\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001COMT\u907a\u4f1d\u5b50\u306eVal158Met\u591a\u578b\u306b\u57fa\u3065\u304f\u7814\u7a76\u3067\u306f\u3001\u4f5c\u696d\u8a18\u61b6\u306e\u6539\u5584\u306b\u9069\u3057\u305f\u65b9\u6cd5\u3068\u3057\u3066\u3001\u77ed\u671f\u9593\u306e\u96c6\u4e2d\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u60c5\u5831\u3092\u57fa\u306b\u3001\u5b66\u7fd2\u30d7\u30e9\u30f3\u3092\u500b\u5225\u306b\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u4f8b\uff1a\u30c7\u30b8\u30bf\u30eb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u5fdc\u7528<\/strong><\/h4>\n\n\n\n<p>AI\u3092\u6d3b\u7528\u3057\u305f\u8a8d\u77e5\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30a2\u30d7\u30ea\u306f\u3001\u500b\u4eba\u306e\u907a\u4f1d\u5b50\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3084\u8a18\u61b6\u529b\u7279\u6027\u306b\u57fa\u3065\u3044\u3066\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u3055\u308c\u305f\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u77ed\u671f\u8a18\u61b6\u304c\u5f31\u3044\u4eba\u306b\u306f\u3001\u8996\u899a\u7684\u306a\u523a\u6fc0\u3092\u7528\u3044\u305f\u30b2\u30fc\u30e0\u5f62\u5f0f\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u63a8\u5968\u3055\u308c\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u969c\u5bb3\u3068\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u306e\u4f4e\u4e0b\u3084\u969c\u5bb3\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u8a8d\u77e5\u75c7\u3084\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff08MCI\uff09\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u30ea\u30b9\u30af\u56e0\u5b50\u3092\u65e9\u671f\u306b\u7279\u5b9a\u3057\u3001\u9069\u5207\u306a\u5bfe\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u8a18\u61b6\u969c\u5bb3\u306e\u4e88\u9632\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3068APOE\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>APOE\u907a\u4f1d\u5b50\u306e\u03b54\u30a2\u30ec\u30eb\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u30ea\u30b9\u30af\u3092\u5927\u5e45\u306b\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u901a\u5e38\u3088\u308a\u65e9\u671f\u306b\u8a18\u61b6\u529b\u306e\u4f4e\u4e0b\u304c\u59cb\u307e\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u03b52\u30a2\u30ec\u30eb\u306f\u4fdd\u8b77\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3001\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u306e\u9032\u5c55<\/strong><\/h4>\n\n\n\n<p>\u3042\u308b\u7814\u7a76\u3067\u306f\u3001APOE-\u03b54\u3092\u6301\u3064\u4eba\u304c\u7279\u5b9a\u306e\u98df\u4e8b\uff08\u5730\u4e2d\u6d77\u5f0f\u98df\u4e8b\u306a\u3069\uff09\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u8a18\u61b6\u529b\u306e\u4f4e\u4e0b\u3092\u9045\u3089\u305b\u308b\u52b9\u679c\u304c\u793a\u3055\u308c\u307e\u3057\u305f\uff08<a href=\"https:\/\/www.alzheimersanddementia.com\/\">\u53c2\u8003\uff1aAlzheimer&#8217;s &amp; Dementia Journal<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u524d\u982d\u5074\u982d\u578b\u8a8d\u77e5\u75c7\u3068MAPT\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u524d\u982d\u5074\u982d\u578b\u8a8d\u77e5\u75c7\uff08FTD\uff09\u306f\u3001MAPT\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306f\u3001\u795e\u7d4c\u7d30\u80de\u306e\u69cb\u9020\u3092\u5b89\u5b9a\u5316\u3055\u305b\u308b\u30bf\u30a6\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3001\u30bf\u30a6\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u7570\u5e38\u306b\u84c4\u7a4d\u3057\u3001\u795e\u7d4c\u6a5f\u80fd\u304c\u640d\u306a\u308f\u308c\u308b\u3053\u3068\u3067\u8a18\u61b6\u529b\u3084\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u304c\u751f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u5229\u70b9<\/strong><\/h4>\n\n\n\n<p>MAPT\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u5834\u5408\u3001\u65e9\u671f\u8a3a\u65ad\u3084\u9032\u884c\u6291\u5236\u306e\u305f\u3081\u306e\u500b\u5225\u5316\u6cbb\u7642\u8a08\u753b\u3092\u7acb\u3066\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u306b\u306f\u3001\u85ac\u7269\u7642\u6cd5\u3084\u7279\u5b9a\u306e\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u4ecb\u5165\u304c\u542b\u307e\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u8a18\u61b6\u529b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/31402630_m-1024x683.jpg\" alt=\"\u52c9\u5f37\u3059\u308b\u5b66\u751f\" class=\"wp-image-2649\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31402630_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31402630_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31402630_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31402630_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/31402630_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306f\u3001\u74b0\u5883\u8981\u56e0\u304c\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u6307\u3057\u307e\u3059\u3002\u3053\u306e\u5206\u91ce\u306e\u7814\u7a76\u306f\u3001\u8a18\u61b6\u529b\u306e\u500b\u4eba\u5dee\u3092\u7406\u89e3\u3057\u3001\u6539\u5584\u7b56\u3092\u898b\u3064\u3051\u308b\u9375\u3092\u63e1\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>DNA\u30e1\u30c1\u30eb\u5316\u3068\u8a18\u61b6\u5f62\u6210<\/strong><\/h3>\n\n\n\n<p>DNA\u30e1\u30c1\u30eb\u5316\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u306e\u4e3b\u8981\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3059\u3002\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u3001\u8a18\u61b6\u5f62\u6210\u3084\u7dad\u6301\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001BDNF\u907a\u4f1d\u5b50\u306e\u30e1\u30c1\u30eb\u5316\u304c\u9032\u3080\u3068\u3001\u795e\u7d4c\u7d30\u80de\u306e\u53ef\u5851\u6027\u304c\u4f4e\u4e0b\u3057\u3001\u8a18\u61b6\u529b\u304c\u640d\u306a\u308f\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u5f71\u97ff<\/strong><\/h4>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u3084\u7761\u7720\u4e0d\u8db3\u3001\u6804\u990a\u4e0d\u8db3\u306f\u3001DNA\u30e1\u30c1\u30eb\u5316\u306e\u30d1\u30bf\u30fc\u30f3\u3092\u5909\u5316\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u904b\u52d5\u3084\u7791\u60f3\u3001\u5065\u5eb7\u7684\u306a\u98df\u4e8b\u306f\u3001\u30e1\u30c1\u30eb\u5316\u3092\u6b63\u5e38\u5316\u3057\u3001\u8a18\u61b6\u529b\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u50cd\u304d\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u6804\u990a\u306e\u95a2\u4fc2\uff1a\u8a18\u61b6\u529b\u3078\u306e\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<p>\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306f\u3001\u6804\u990a\u7d20\u306e\u4ee3\u8b1d\u3084\u8133\u5185\u3067\u306e\u5229\u7528\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u3053\u308c\u306b\u57fa\u3065\u304d\u3001\u500b\u3005\u306e\u907a\u4f1d\u5b50\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u5fdc\u3058\u305f\u98df\u4e8b\u304c\u3001\u8a18\u61b6\u529b\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u91cd\u8981\u306a\u8981\u7d20\u3068\u306a\u308a\u5f97\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30d3\u30bf\u30df\u30f3B\u7fa4\u3068MTHFR\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>MTHFR\uff08\u30e1\u30c1\u30ec\u30f3\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u8449\u9178\u9084\u5143\u9175\u7d20\uff09\u907a\u4f1d\u5b50\u306f\u3001\u8449\u9178\u3084\u30d3\u30bf\u30df\u30f3B12\u306e\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3001\u30db\u30e2\u30b7\u30b9\u30c6\u30a4\u30f3\u306e\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u3001\u8a18\u61b6\u529b\u4f4e\u4e0b\u3084\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u306e\u5897\u52a0\u306b\u7e4b\u304c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u8449\u9178\u3084\u30d3\u30bf\u30df\u30f3B12\u3092\u88dc\u7d66\u3059\u308b\u3053\u3068\u3067\u3001\u3053\u308c\u3089\u306e\u5f71\u97ff\u3092\u8efd\u6e1b\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3068FABP7\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>FABP7\uff08\u8102\u80aa\u9178\u7d50\u5408\u30bf\u30f3\u30d1\u30af\u8cea7\uff09\u907a\u4f1d\u5b50\u306f\u3001\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u306e\u8133\u5185\u8f38\u9001\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u304c\u5341\u5206\u3067\u306a\u3044\u5834\u5408\u3001\u8133\u306e\u5065\u5eb7\u3084\u8a18\u61b6\u529b\u304c\u640d\u306a\u308f\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u9b5a\u985e\u3084\u30ca\u30c3\u30c4\u985e\u306b\u8c4a\u5bcc\u306b\u542b\u307e\u308c\u308b\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u8a18\u61b6\u529b\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u529b\u7814\u7a76\u306e\u672a\u6765\u3068\u907a\u4f1d\u5b50\u6280\u8853\u306e\u53ef\u80fd\u6027<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u5225\u5316\u3055\u308c\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u6cbb\u7642\u3001\u3055\u3089\u306b\u306f\u65b0\u3057\u3044\u8a18\u61b6\u5f37\u5316\u6280\u8853\u306e\u958b\u767a\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>AI\u3068\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u306e\u6d3b\u7528<\/strong><\/h3>\n\n\n\n<p>AI\u3084\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u89e3\u6790\u306f\u3001\u8a18\u61b6\u529b\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u306e\u81a8\u5927\u306a\u60c5\u5831\u3092\u89e3\u6790\u3057\u3001\u500b\u4eba\u306b\u6700\u9069\u306a\u5b66\u7fd2\u6cd5\u3084\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5\u3092\u63d0\u6848\u3059\u308b\u3053\u3068\u3092\u53ef\u80fd\u306b\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001AI\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u30c7\u30fc\u30bf\u3068\u884c\u52d5\u8a18\u9332\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u3001\u52b9\u7387\u7684\u306a\u8a18\u61b6\u529b\u5411\u4e0a\u30d7\u30e9\u30f3\u3092\u751f\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306e\u672a\u6765<\/strong><\/h3>\n\n\n\n<p>CRISPR-Cas9\u306a\u3069\u306e\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306f\u3001\u8a18\u61b6\u529b\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u3092\u76f4\u63a5\u64cd\u4f5c\u3059\u308b\u3053\u3068\u3067\u3001\u8a18\u61b6\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u6280\u8853\u306f\u3001\u8a8d\u77e5\u75c7\u3084\u8a18\u61b6\u969c\u5bb3\u306e\u6cbb\u7642\u3060\u3051\u3067\u306a\u304f\u3001\u5b66\u7fd2\u80fd\u529b\u306e\u5f37\u5316\u306b\u3082\u5fdc\u7528\u3067\u304d\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u305f\u3060\u3057\u3001\u502b\u7406\u7684\u306a\u554f\u984c\u3084\u9577\u671f\u7684\u306a\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u8a18\u61b6\u529b\u306e\u76f8\u95a2\u6027\uff1a\u500b\u4f53\u5dee\u306e\u7406\u89e3\u3092\u6df1\u3081\u308b<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u306e\u500b\u4f53\u5dee\u3092\u6c7a\u5b9a\u3059\u308b\u907a\u4f1d\u7684\u8981\u56e0\u306f\u8907\u96d1\u3067\u3001\u6570\u591a\u304f\u306e\u907a\u4f1d\u5b50\u304c\u76f8\u4e92\u4f5c\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u305d\u308c\u305e\u308c\u306e\u907a\u4f1d\u5b50\u304c\u7570\u306a\u308b\u5074\u9762\u3067\u8a18\u61b6\u529b\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u305f\u3081\u3001\u7dcf\u5408\u7684\u306a\u7406\u89e3\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u591a\u907a\u4f1d\u5b50\u30e2\u30c7\u30eb\u3068\u8a18\u61b6\u529b\u306e\u500b\u4f53\u5dee<\/strong><\/h3>\n\n\n\n<p>\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u306f\u3001\u8a18\u61b6\u529b\u3092\u8aac\u660e\u3059\u308b\u5358\u4e00\u306e\u300c\u8a18\u61b6\u529b\u907a\u4f1d\u5b50\u300d\u3068\u3044\u3046\u3082\u306e\u306f\u5b58\u5728\u305b\u305a\u3001\u591a\u304f\u306e\u907a\u4f1d\u5b50\u304c\u5c11\u3057\u305a\u3064\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3092<strong>\u591a\u907a\u4f1d\u5b50\u30e2\u30c7\u30eb<\/strong>\u3068\u547c\u3073\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001BDNF\u3001GRIN2B\u3001COMT\u3001APOE\u306a\u3069\u306e\u907a\u4f1d\u5b50\u304c\u4e92\u3044\u306b\u5f71\u97ff\u3057\u5408\u3044\u3001\u8a18\u61b6\u306e\u5f37\u5316\u3084\u8870\u9000\u3092\u8abf\u7bc0\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u89e3\u6790\uff08GWAS\uff09\u306e\u8ca2\u732e<\/strong><\/h4>\n\n\n\n<p>GWAS\uff08Genome-Wide Association Studies\uff09\u306f\u3001\u8a18\u61b6\u529b\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u3092\u7279\u5b9a\u3059\u308b\u305f\u3081\u306e\u91cd\u8981\u306a\u624b\u6cd5\u3067\u3059\u3002\u3053\u306e\u89e3\u6790\u306b\u3088\u3063\u3066\u3001\u5fae\u5c0f\u306a\u907a\u4f1d\u5b50\u5909\u7570\uff08SNP\uff1a\u4e00\u5869\u57fa\u591a\u578b\uff09\u304c\u8a18\u61b6\u529b\u306b\u3069\u306e\u3088\u3046\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u304b\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u30012018\u5e74\u306e\u5927\u898f\u6a21\u7814\u7a76\u3067\u306f\u3001\u7d0430\u306e\u65b0\u3057\u3044\u907a\u4f1d\u5b50\u304c\u8a18\u61b6\u529b\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41467-018-04385-3\">\u53c2\u8003\uff1aNature Communications<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u795e\u7d4c\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3078\u306e\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>\u8a18\u61b6\u529b\u306f\u3001\u8133\u5185\u306e\u795e\u7d4c\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u3088\u3063\u3066\u652f\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u6d77\u99ac\u3084\u524d\u982d\u524d\u91ce\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u9818\u57df\u306e\u6a5f\u80fd\u3092\u8abf\u7bc0\u3059\u308b\u907a\u4f1d\u5b50\u304c\u8a18\u61b6\u529b\u306e\u5411\u4e0a\u307e\u305f\u306f\u4f4e\u4e0b\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u6d77\u99ac\u306e\u795e\u7d4c\u65b0\u751f\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308bBDNF\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u9ad8\u3044\u5834\u5408\u3001\u65b0\u3057\u3044\u8a18\u61b6\u3092\u52b9\u7387\u7684\u306b\u5f62\u6210\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-07ca3791-7fff-5b7b-a5de-7eb0a4cac5b8\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u529b\u3068\u907a\u4f1d\u7684\u8981\u56e0\u306e\u5730\u57df\u5dee<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/2742365_m-1024x683.jpg\" alt=\"\u8857\u4e26\u307f\" class=\"wp-image-2656\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/2742365_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/2742365_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/2742365_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/2742365_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/2742365_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306f\u3001\u5730\u57df\u3084\u6c11\u65cf\u306b\u3088\u3063\u3066\u5206\u5e03\u304c\u7570\u306a\u308a\u3001\u305d\u308c\u306b\u4f34\u3063\u3066\u8a18\u61b6\u529b\u306e\u7279\u6027\u3082\u5909\u5316\u3057\u307e\u3059\u3002\u3053\u306e\u5730\u57df\u5dee\u306f\u3001\u9032\u5316\u7684\u306a\u9069\u5fdc\u3084\u74b0\u5883\u8981\u56e0\u306b\u3088\u3063\u3066\u5f62\u6210\u3055\u308c\u3066\u304d\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>APOE\u907a\u4f1d\u5b50\u306e\u5206\u5e03\u3068\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>APOE\u907a\u4f1d\u5b50\u306e\u30a2\u30ec\u30eb\uff08\u03b52\u3001\u03b53\u3001\u03b54\uff09\u306f\u3001\u5730\u57df\u3054\u3068\u306b\u5206\u5e03\u304c\u7570\u306a\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001APOE-\u03b54\u306e\u983b\u5ea6\u306f\u3001\u5317\u6b27\u8af8\u56fd\u3067\u9ad8\u304f\u3001\u30a2\u30d5\u30ea\u30ab\u3067\u306f\u6bd4\u8f03\u7684\u4f4e\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u9055\u3044\u306f\u3001\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u3084\u8a18\u61b6\u529b\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u5730\u57df\u7684\u306a\u5dee\u7570\u3092\u3082\u305f\u3089\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u9032\u5316\u7684\u9069\u5fdc\u3068\u8a18\u61b6\u529b\u306e\u9055\u3044<\/strong><\/h3>\n\n\n\n<p>\u9032\u5316\u306e\u904e\u7a0b\u3067\u3001\u4eba\u3005\u304c\u9069\u5fdc\u3057\u305f\u74b0\u5883\u304c\u8a18\u61b6\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u305f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u5bd2\u51b7\u5730\u3067\u306f\u3001\u72e9\u731f\u3084\u8907\u96d1\u306a\u793e\u4f1a\u7684\u76f8\u4e92\u4f5c\u7528\u3092\u5fc5\u8981\u3068\u3059\u308b\u751f\u6d3b\u304c\u8a18\u61b6\u529b\u3092\u9ad8\u3081\u308b\u907a\u4f1d\u5b50\u306e\u9078\u629e\u3092\u4fc3\u3057\u305f\u3068\u3059\u308b\u4eee\u8aac\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3001\u71b1\u5e2f\u5730\u57df\u3067\u306f\u3001\u98df\u7269\u306e\u53ce\u96c6\u3084\u5373\u6642\u7684\u306a\u8a18\u61b6\u304c\u512a\u4f4d\u6027\u3092\u6301\u3064\u74b0\u5883\u8981\u56e0\u304c\u5f71\u97ff\u3057\u305f\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-07ca3791-7fff-5b7b-a5de-7eb0a4cac5b8\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u529b\u3068\u7761\u7720\u306e\u907a\u4f1d\u7684\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u7761\u7720\u306f\u8a18\u61b6\u306e\u56fa\u5b9a\u5316\uff08\u8a18\u61b6\u306e\u7d71\u5408\u3068\u4fdd\u5b58\uff09\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u304a\u308a\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>ADRB1\u907a\u4f1d\u5b50\u3068\u7761\u7720\u30d1\u30bf\u30fc\u30f3<\/strong><\/h3>\n\n\n\n<p>ADRB1\u907a\u4f1d\u5b50\u306f\u3001\u899a\u9192\u3068\u7761\u7720\u306e\u30ea\u30ba\u30e0\u3092\u8abf\u7bc0\u3059\u308b\u5f79\u5272\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3001\u7761\u7720\u6642\u9593\u306e\u77ed\u7e2e\u3084\u7761\u7720\u306e\u8cea\u306e\u4f4e\u4e0b\u304c\u8a18\u61b6\u529b\u306b\u60aa\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u9069\u5207\u306a\u7761\u7720\u306f\u3001\u7279\u306b\u6d77\u99ac\u3067\u306e\u8a18\u61b6\u56fa\u5b9a\u5316\u3092\u52a9\u3051\u308b\u305f\u3081\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u306f\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7761\u7720\u3068\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u5909\u5316<\/strong><\/h3>\n\n\n\n<p>\u7814\u7a76\u3067\u306f\u3001\u7761\u7720\u4e0d\u8db3\u304cBDNF\u3084COMT\u306a\u3069\u8a18\u61b6\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306b\u60aa\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u30b7\u30ca\u30d7\u30b9\u306e\u53ef\u5851\u6027\u304c\u4f4e\u4e0b\u3057\u3001\u65b0\u3057\u3044\u60c5\u5831\u306e\u5b66\u7fd2\u304c\u56f0\u96e3\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u5341\u5206\u306a\u7761\u7720\u3092\u53d6\u308b\u3053\u3068\u3067\u3001\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u56de\u5fa9\u3057\u3001\u8a18\u61b6\u5f62\u6210\u80fd\u529b\u304c\u5411\u4e0a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u529b\u3068\u30db\u30eb\u30e2\u30f3\u306e\u907a\u4f1d\u7684\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<p>\u30db\u30eb\u30e2\u30f3\u306f\u3001\u8a18\u61b6\u529b\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u8981\u56e0\u306e\u4e00\u3064\u3067\u3059\u3002\u305d\u306e\u8abf\u7bc0\u3092\u62c5\u3046\u907a\u4f1d\u5b50\u306f\u3001\u8a18\u61b6\u529b\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u76f4\u63a5\u7684\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u3068\u30b9\u30c8\u30ec\u30b9\u53cd\u5fdc<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306f\u3001\u904e\u5270\u306a\u5206\u6ccc\u304c\u8a18\u61b6\u529b\u306b\u60aa\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u3067\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001NR3C1\uff08\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\uff09\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3001\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u3078\u306e\u611f\u53d7\u6027\u304c\u5909\u5316\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u74b0\u5883\u4e0b\u3067\u306e\u8a18\u61b6\u529b\u4f4e\u4e0b\u304c\u9855\u8457\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u4f8b<\/strong><\/h4>\n\n\n\n<p>NR3C1\u907a\u4f1d\u5b50\u306b\u95a2\u9023\u3059\u308b\u7814\u7a76\u3067\u306f\u3001\u5909\u7570\u304c\u3042\u308b\u500b\u4f53\u306f\u3001\u6162\u6027\u7684\u306a\u30b9\u30c8\u30ec\u30b9\u4e0b\u3067\u306e\u8a18\u61b6\u529b\u30c6\u30b9\u30c8\u306e\u6210\u7e3e\u304c\u5e73\u5747\u3088\u308a\u4f4e\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u305f\u3081\u3001\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u304c\u8a18\u61b6\u529b\u7dad\u6301\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6027\u30db\u30eb\u30e2\u30f3\u3068\u8a18\u61b6\u529b<\/strong><\/h3>\n\n\n\n<p>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u3084\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306a\u3069\u306e\u6027\u30db\u30eb\u30e2\u30f3\u306f\u3001\u8a18\u61b6\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306f\u3001BDNF\u306e\u767a\u73fe\u3092\u4fc3\u9032\u3057\u3001\u795e\u7d4c\u53ef\u5851\u6027\u3092\u9ad8\u3081\u308b\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u6027\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u91cf\u304c\u4f4e\u4e0b\u3059\u308b\u3068\u3001\u8a18\u61b6\u529b\u304c\u8870\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u529b\u7814\u7a76\u306e\u672a\u6765\u5c55\u671b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/22927494_m-1024x683.jpg\" alt=\"\u30bf\u30d6\u30ec\u30c3\u30c8\u5b66\u7fd2\" class=\"wp-image-2663\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22927494_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22927494_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22927494_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22927494_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22927494_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u3068\u8a18\u61b6\u529b\u306b\u95a2\u3059\u308b\u7814\u7a76\u306f\u3001\u500b\u5225\u5316\u533b\u7642\u3084\u6559\u80b2\u5206\u91ce\u306b\u304a\u3044\u3066\u5927\u304d\u306a\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u500b\u5225\u5316\u6559\u80b2\u306e\u5b9f\u73fe<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u57fa\u306b\u3001\u5b66\u7fd2\u30b9\u30bf\u30a4\u30eb\u3084\u8a18\u61b6\u306e\u5f37\u5316\u65b9\u6cd5\u3092\u500b\u5225\u306b\u6700\u9069\u5316\u3059\u308b\u53d6\u308a\u7d44\u307f\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u77ed\u671f\u8a18\u61b6\u304c\u5f37\u3044\u30bf\u30a4\u30d7\u306e\u5b66\u7fd2\u8005\u306b\u306f\u3001\u30d5\u30e9\u30c3\u30b7\u30e5\u30ab\u30fc\u30c9\u306e\u3088\u3046\u306a\u53cd\u5fa9\u578b\u5b66\u7fd2\u304c\u52b9\u679c\u7684\u3067\u3042\u308b\u4e00\u65b9\u3001\u9577\u671f\u8a18\u61b6\u306b\u512a\u308c\u308b\u5b66\u7fd2\u8005\u306b\u306f\u3001\u6df1\u3044\u7406\u89e3\u3092\u91cd\u8996\u3057\u305f\u30ab\u30ea\u30ad\u30e5\u30e9\u30e0\u304c\u9069\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u8a8d\u77e5\u75c7\u4e88\u9632\u3068\u65e9\u671f\u4ecb\u5165<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b\u30ea\u30b9\u30af\u8a55\u4fa1\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3084\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306e\u4e88\u9632\u7b56\u3092\u65e9\u671f\u306b\u8b1b\u3058\u308b\u9053\u3092\u958b\u304d\u307e\u3059\u3002\u3053\u308c\u306b\u306f\u3001\u751f\u6d3b\u7fd2\u6163\u306e\u898b\u76f4\u3057\u3084\u7279\u5b9a\u306e\u6804\u990a\u7d20\u306e\u6442\u53d6\u3001\u3055\u3089\u306b\u306f\u8a8d\u77e5\u6a5f\u80fd\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u5c0e\u5165\u304c\u542b\u307e\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-07ca3791-7fff-5b7b-a5de-7eb0a4cac5b8\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u529b\u3068\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\uff1a\u907a\u4f1d\u5b50\u306e\u5f79\u5272<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u306b\u306f\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u50cd\u304d\u304c\u4e0d\u53ef\u6b20\u3067\u3042\u308a\u3001\u305d\u308c\u3092\u5236\u5fa1\u3059\u308b\u907a\u4f1d\u5b50\u304c\u8a18\u61b6\u529b\u306e\u5411\u4e0a\u3084\u4f4e\u4e0b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u3001\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306a\u3069\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306f\u3001\u5b66\u7fd2\u3084\u8a18\u61b6\u5f62\u6210\u306b\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30c9\u30fc\u30d1\u30df\u30f3\u3068DRD2\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u30c9\u30fc\u30d1\u30df\u30f3\u306f\u3001\u5831\u916c\u7cfb\u3084\u52d5\u6a5f\u4ed8\u3051\u3001\u4f5c\u696d\u8a18\u61b6\u306b\u95a2\u9023\u3059\u308b\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3067\u3059\u3002DRD2\uff08\u30c9\u30fc\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53D2\uff09\u907a\u4f1d\u5b50\u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u4fe1\u53f7\u4f1d\u9054\u306e\u8abf\u7bc0\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u77ed\u671f\u8a18\u61b6\u3084\u96c6\u4e2d\u529b\u306e\u4f4e\u4e0b\u3001\u5b66\u7fd2\u52b9\u7387\u306e\u4f4e\u4e0b\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u5b9f\u4f8b<\/strong><\/h4>\n\n\n\n<p>2015\u5e74\u306b\u884c\u308f\u308c\u305f\u7814\u7a76\u3067\u306f\u3001DRD2\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u591a\u578b\u3092\u6301\u3064\u4eba\u3005\u304c\u3001\u8a18\u61b6\u529b\u3084\u6ce8\u610f\u529b\u306e\u8ab2\u984c\u306b\u304a\u3044\u3066\u4ed6\u306e\u30b0\u30eb\u30fc\u30d7\u3088\u308a\u3082\u4f4e\u3044\u6210\u7e3e\u3092\u793a\u3059\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u305f\u3060\u3057\u3001\u74b0\u5883\u8981\u56e0\uff08\u4f8b\uff1a\u8a8d\u77e5\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u9069\u5207\u306a\u98df\u4e8b\uff09\u304c\u5f71\u97ff\u3092\u7de9\u548c\u3059\u308b\u53ef\u80fd\u6027\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u3068GRM3\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u306f\u3001\u8133\u306e\u4e3b\u8981\u306a\u8208\u596e\u6027\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3067\u3042\u308a\u3001\u8a18\u61b6\u5f62\u6210\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002GRM3\uff08\u30e1\u30bf\u30dc\u30c8\u30ed\u30d4\u30c3\u30af\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u53d7\u5bb9\u4f533\uff09\u907a\u4f1d\u5b50\u306f\u3001\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u8abf\u7bc0\u3057\u3001\u77ed\u671f\u8a18\u61b6\u3068\u4f5c\u696d\u8a18\u61b6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u4f8b<\/strong><\/h4>\n\n\n\n<p>GRM3\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570\u306f\u3001\u77ed\u671f\u8a18\u61b6\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u4f4e\u4e0b\u3084\u7cbe\u795e\u75be\u60a3\uff08\u4f8b\uff1a\u7d71\u5408\u5931\u8abf\u75c7\uff09\u3068\u306e\u95a2\u9023\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u3092\u6a19\u7684\u3068\u3057\u305f\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u9032\u884c\u4e2d\u3067\u3042\u308a\u3001\u8a18\u61b6\u529b\u6539\u5584\u3078\u306e\u5fdc\u7528\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u529b\u306b\u95a2\u3059\u308b\u6027\u5dee\u3068\u30db\u30eb\u30e2\u30f3\u306e\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<p>\u8a18\u61b6\u529b\u306b\u306f\u6027\u5dee\u304c\u5b58\u5728\u3057\u3001\u305d\u308c\u306f\u4e3b\u306b\u30db\u30eb\u30e2\u30f3\u306e\u5f71\u97ff\u306b\u3088\u308b\u3082\u306e\u3067\u3059\u3002\u7537\u6027\u3068\u5973\u6027\u3067\u306f\u3001\u8a18\u61b6\u529b\u306e\u7a2e\u985e\u3084\u8133\u306e\u4f7f\u3044\u65b9\u306b\u9055\u3044\u304c\u898b\u3089\u308c\u307e\u3059\u304c\u3001\u3053\u308c\u3089\u306e\u9055\u3044\u3092\u5236\u5fa1\u3059\u308b\u907a\u4f1d\u5b50\u3082\u7279\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6027\u30db\u30eb\u30e2\u30f3\u3068\u8a18\u61b6\u529b\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u3068\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306f\u3001\u8a18\u61b6\u529b\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306f\u3001\u6d77\u99ac\u3067\u306e\u30b7\u30ca\u30d7\u30b9\u5f62\u6210\u3092\u4fc3\u9032\u3057\u3001\u30a8\u30d4\u30bd\u30fc\u30c9\u8a18\u61b6\uff08\u51fa\u6765\u4e8b\u306e\u8a18\u61b6\uff09\u3084\u8a00\u8a9e\u8a18\u61b6\u3092\u5411\u4e0a\u3055\u305b\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306f\u3001\u7a7a\u9593\u8a8d\u77e5\u80fd\u529b\u3084\u8996\u899a\u8a18\u61b6\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>ESR1\u907a\u4f1d\u5b50\u3068\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53<\/strong><\/h4>\n\n\n\n<p>ESR1\u907a\u4f1d\u5b50\u306f\u3001\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u306e\u767a\u73fe\u3092\u5236\u5fa1\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570\u306f\u3001\u5973\u6027\u306b\u304a\u3051\u308b\u8a18\u61b6\u529b\u306e\u500b\u4f53\u5dee\u3084\u3001\u9589\u7d4c\u5f8c\u306e\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3068\u95a2\u9023\u304c\u3042\u308a\u307e\u3059\u3002\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u7642\u6cd5\u3092\u7528\u3044\u305f\u7814\u7a76\u3067\u306f\u3001ESR1\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306b\u3088\u3063\u3066\u6cbb\u7642\u52b9\u679c\u304c\u7570\u306a\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6027\u5dee\u3068\u5b66\u7fd2\u6226\u7565\u306e\u9055\u3044<\/strong><\/h3>\n\n\n\n<p>\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u5973\u6027\u306f\u901a\u5e38\u3001\u8a00\u8a9e\u8a18\u61b6\u3084\u30a8\u30d4\u30bd\u30fc\u30c9\u8a18\u61b6\u306b\u304a\u3044\u3066\u512a\u308c\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u793a\u3057\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u7537\u6027\u306f\u7a7a\u9593\u8a18\u61b6\u3084\u5730\u56f3\u306e\u8aad\u307f\u53d6\u308a\u306a\u3069\u306e\u30bf\u30b9\u30af\u3067\u512a\u4f4d\u6027\u3092\u6301\u3064\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u6027\u5dee\u306f\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3068\u305d\u308c\u3092\u5236\u5fa1\u3059\u308b\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u8a18\u61b6\u529b\u306e\u4f4e\u4e0b\u3092\u9632\u3050\u305f\u3081\u306e\u5b9f\u7528\u7684\u30a2\u30d7\u30ed\u30fc\u30c1<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"681\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/22257730_m-1024x681.jpg\" alt=\"\u9b5a\u5b9a\u98df\" class=\"wp-image-2670\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22257730_m-1024x681.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22257730_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22257730_m-768x511.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22257730_m-1536x1022.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/22257730_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u3068\u8a18\u61b6\u529b\u306e\u95a2\u4fc2\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u8a18\u61b6\u529b\u3092\u7dad\u6301\u30fb\u5411\u4e0a\u3055\u305b\u308b\u305f\u3081\u306e\u5177\u4f53\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u306b\u306f\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u6539\u5584\u3084\u79d1\u5b66\u7684\u306b\u88cf\u4ed8\u3051\u3089\u308c\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5\u306e\u6d3b\u7528\u304c\u542b\u307e\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6804\u990a\u88dc\u7d66\u3068\u8133\u306e\u5065\u5eb7<\/strong><\/h3>\n\n\n\n<p>\u7279\u5b9a\u306e\u6804\u990a\u7d20\u304c\u907a\u4f1d\u5b50\u767a\u73fe\u306b\u30d7\u30e9\u30b9\u306e\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u8a18\u61b6\u529b\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30aa\u30e1\u30ac3\u8102\u80aa\u9178<\/strong>\uff1a\u9b5a\u306b\u542b\u307e\u308c\u308bDHA\u306f\u3001\u6d77\u99ac\u3067\u306e\u30b7\u30ca\u30d7\u30b9\u5f62\u6210\u3092\u4fc3\u9032\u3057\u3001BDNF\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u9ad8\u3081\u308b\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb<\/strong>\uff1a\u30d6\u30eb\u30fc\u30d9\u30ea\u30fc\u3084\u7dd1\u8336\u306b\u542b\u307e\u308c\u308b\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306f\u3001\u6297\u9178\u5316\u4f5c\u7528\u3092\u6301\u3061\u3001\u8133\u7d30\u80de\u306e\u640d\u50b7\u3092\u9632\u3050\u3053\u3068\u3067\u8a18\u61b6\u529b\u306e\u7dad\u6301\u3092\u52a9\u3051\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u30d3\u30bf\u30df\u30f3B\u7fa4<\/strong>\uff1a\u8449\u9178\u3084\u30d3\u30bf\u30df\u30f3B12\u306f\u3001MTHFR\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u3001\u8a18\u61b6\u529b\u4f4e\u4e0b\u3092\u4e88\u9632\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u77e5\u7684\u6d3b\u52d5\u306e\u52b9\u679c<\/strong><\/h3>\n\n\n\n<p>\u30af\u30ed\u30b9\u30ef\u30fc\u30c9\u3084\u30c1\u30a7\u30b9\u3001\u697d\u5668\u306e\u6f14\u594f\u3068\u3044\u3063\u305f\u77e5\u7684\u6d3b\u52d5\u306f\u3001\u8133\u5185\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u5f37\u5316\u3057\u3001\u8a18\u61b6\u529b\u3092\u5411\u4e0a\u3055\u305b\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u6d3b\u52d5\u306f\u3001\u65b0\u3057\u3044\u795e\u7d4c\u7d4c\u8def\u3092\u5f62\u6210\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u8133\u306e\u67d4\u8edf\u6027\u3092\u4fdd\u3064\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 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