{"id":453,"date":"2024-11-14T01:00:22","date_gmt":"2024-11-14T01:00:22","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=453"},"modified":"2025-04-09T02:45:39","modified_gmt":"2025-04-09T02:45:39","slug":"family-genetic-testing-benefits-usage","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/family-genetic-testing-benefits-usage\/","title":{"rendered":"\u907a\u4f1d\u5b50\u9451\u5b9a\u3068\u5bb6\u5ead\u306e\u672a\u6765\uff1a\u60c5\u5831\u3092\u3069\u3046\u6d3b\u7528\u3059\u308b\u304b"},"content":{"rendered":"\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u306f\u3058\u3081\u306b\uff1a\u907a\u4f1d\u5b50\u60c5\u5831\u304c\u3082\u305f\u3089\u3059\u672a\u6765<\/strong><\/h2>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u9451\u5b9a\u306e\u6280\u8853\u304c\u98db\u8e8d\u7684\u306b\u9032\u5316\u3057\u3001\u4e00\u822c\u5bb6\u5ead\u3067\u3082\u624b\u8efd\u306b\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u500b\u4eba\u306e\u5065\u5eb7\u30ea\u30b9\u30af\u306e\u4e88\u6e2c\u3001\u30eb\u30fc\u30c4\u306e\u63a2\u7d22\u3001\u3055\u3089\u306b\u306f\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u3055\u308c\u305f\u533b\u7642\u3078\u306e\u5fdc\u7528\u306a\u3069\u3001\u305d\u306e\u53ef\u80fd\u6027\u306f\u7121\u9650\u5927\u3067\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u907a\u4f1d\u5b50\u9451\u5b9a\u306e\u57fa\u672c\u304b\u3089\u3001\u5bb6\u5ead\u3067\u306e\u6d3b\u7528\u65b9\u6cd5\u3001\u502b\u7406\u7684\u306a\u8ab2\u984c\u307e\u3067\u3092\u5305\u62ec\u7684\u306b\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u9451\u5b9a\u3068\u306f\uff1f<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1-1. \u907a\u4f1d\u5b50\u3068\u306f\u4f55\u304b<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\uff08DNA\uff09\u306f\u751f\u7269\u306e\u8a2d\u8a08\u56f3\u3068\u3082\u547c\u3070\u308c\u308b\u60c5\u5831\u306e\u96c6\u5408\u4f53\u3067\u3042\u308a\u3001\u89aa\u304b\u3089\u5b50\u3078\u3068\u53d7\u3051\u7d99\u304c\u308c\u307e\u3059\u3002DNA\u306f\u7d0430\u5104\u5869\u57fa\u5bfe\u3067\u69cb\u6210\u3055\u308c\u3066\u304a\u308a\u3001\u4eba\u9593\u306e\u4f53\u306e\u3042\u3089\u3086\u308b\u7279\u5fb4\u3084\u6a5f\u80fd\u3092\u6c7a\u5b9a\u3059\u308b\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1-2. \u907a\u4f1d\u5b50\u9451\u5b9a\u306e\u4ed5\u7d44\u307f<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u9451\u5b9a\u3067\u306f\u3001DNA\u30b5\u30f3\u30d7\u30eb\uff08\u553e\u6db2\u3084\u8840\u6db2\u306a\u3069\uff09\u3092\u63a1\u53d6\u3057\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u914d\u5217\u3092\u5206\u6790\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u4eba\u306e\u4f53\u8cea\u3084\u75c5\u6c17\u306e\u30ea\u30b9\u30af\u3001\u7956\u5148\u306e\u30eb\u30fc\u30c4\u306a\u3069\u3092\u8abf\u3079\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1-3. \u907a\u4f1d\u5b50\u9451\u5b9a\u306e\u7a2e\u985e<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5065\u5eb7\u30ea\u30b9\u30af\u9451\u5b9a<\/strong>\uff1a\u7cd6\u5c3f\u75c5\u3084\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306a\u3069\u306e\u30ea\u30b9\u30af\u3092\u4e88\u6e2c<\/li>\n\n\n\n<li><strong>\u7956\u5148\u89e3\u6790<\/strong>\uff1a\u907a\u4f1d\u7684\u30eb\u30fc\u30c4\u3092\u7279\u5b9a\u3057\u3001\u5bb6\u7cfb\u56f3\u306e\u4f5c\u6210\u3092\u652f\u63f4<\/li>\n\n\n\n<li><strong>\u85ac\u7406\u907a\u4f1d\u5b66<\/strong>\uff1a\u85ac\u306e\u52b9\u679c\u3084\u526f\u4f5c\u7528\u306e\u500b\u4eba\u5dee\u3092\u4e88\u6e2c<\/li>\n\n\n\n<li><strong>\u624d\u80fd\u30fb\u4f53\u8cea\u9451\u5b9a<\/strong>\uff1a\u904b\u52d5\u80fd\u529b\u3084\u98df\u4e8b\u306e\u9069\u6027\u3092\u5206\u6790<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u907a\u4f1d\u5b50\u9451\u5b9a\u306e\u5bb6\u5ead\u3067\u306e\u6d3b\u7528\u65b9\u6cd5<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2-1. \u5065\u5eb7\u7ba1\u7406\u3078\u306e\u5fdc\u7528<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u3063\u3066\u5f97\u3089\u308c\u305f\u30c7\u30fc\u30bf\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u5bb6\u65cf\u306e\u5065\u5eb7\u7ba1\u7406\u3092\u3088\u308a\u52b9\u679c\u7684\u306b\u884c\u3046\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u7279\u5b9a\u306e\u75c5\u6c17\u306b\u304b\u304b\u308a\u3084\u3059\u3044\u907a\u4f1d\u7684\u50be\u5411\u304c\u5224\u660e\u3057\u305f\u5834\u5408\u3001\u98df\u4e8b\u3084\u751f\u6d3b\u7fd2\u6163\u3092\u898b\u76f4\u3059\u3053\u3068\u3067\u767a\u75c7\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1a\u4e73\u304c\u3093\u306e\u907a\u4f1d\u5b50\u5909\u7570\uff08BRCA1\/BRCA2\uff09<\/strong><strong><br><\/strong> BRCA1\/BRCA2\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3001\u4e73\u304c\u3093\u3084\u5375\u5de3\u304c\u3093\u306e\u30ea\u30b9\u30af\u304c\u5927\u5e45\u306b\u4e0a\u6607\u3057\u307e\u3059\u3002\u3053\u306e\u60c5\u5831\u3092\u3082\u3068\u306b\u3001\u5b9a\u671f\u691c\u8a3a\u306e\u983b\u5ea6\u3092\u5897\u3084\u3057\u305f\u308a\u3001\u4e88\u9632\u7684\u306a\u63aa\u7f6e\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2-2. \u89aa\u5b50\u95a2\u4fc2\u3068\u5bb6\u7cfb\u306e\u7406\u89e3<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u9451\u5b9a\u306f\u3001\u89aa\u5b50\u95a2\u4fc2\u306e\u78ba\u8a8d\u3084\u7956\u5148\u306e\u30eb\u30fc\u30c4\u3092\u63a2\u308b\u969b\u306b\u3082\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5bb6\u65cf\u306e\u6b74\u53f2\u3092\u77e5\u308b\u3053\u3068\u3067\u3001\u30a2\u30a4\u30c7\u30f3\u30c6\u30a3\u30c6\u30a3\u306e\u78ba\u7acb\u3084\u6587\u5316\u7684\u80cc\u666f\u306e\u7406\u89e3\u304c\u6df1\u307e\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1a\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u5206\u6790<\/strong><strong><br><\/strong> \u6bcd\u7cfb\u306e\u30eb\u30fc\u30c4\u3092\u305f\u3069\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u5206\u6790\u306b\u3088\u3063\u3066\u3001\u6570\u767e\u5e74\u524d\u306e\u7956\u5148\u306e\u79fb\u52d5\u7d4c\u8def\u304c\u5224\u660e\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2-3. \u907a\u4f1d\u5b50\u306b\u57fa\u3065\u304f\u6559\u80b2\u3068\u80b2\u5150<\/strong><\/h3>\n\n\n\n<p>\u5b50\u3069\u3082\u306e\u624d\u80fd\u3084\u9069\u6027\u3092\u907a\u4f1d\u5b50\u60c5\u5831\u304b\u3089\u628a\u63e1\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u3005\u306b\u9069\u3057\u305f\u6559\u80b2\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1aACTN3\u907a\u4f1d\u5b50\u3068\u904b\u52d5\u80fd\u529b<\/strong><strong><br><\/strong> ACTN3\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u77ac\u767a\u529b\u304c\u9ad8\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u60c5\u5831\u3092\u3082\u3068\u306b\u3001\u30b9\u30dd\u30fc\u30c4\u306e\u9069\u6027\u3092\u5224\u65ad\u3059\u308b\u3053\u3068\u3082\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u907a\u4f1d\u5b50\u60c5\u5831\u306e\u8ab2\u984c\u3068\u502b\u7406\u7684\u5074\u9762<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/1490661_m-1024x683.jpg\" alt=\"\u533b\u8005\u3068\u89aa\u5b502\" class=\"wp-image-8696\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/1490661_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/1490661_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/1490661_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/1490661_m-1536x1025.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/1490661_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-1. \u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u3068\u30c7\u30fc\u30bf\u4fdd\u8b77<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306f\u6975\u3081\u3066\u500b\u4eba\u7684\u306a\u30c7\u30fc\u30bf\u3067\u3042\u308a\u3001\u5916\u90e8\u3078\u306e\u6f0f\u6d29\u3084\u60aa\u7528\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002\u907a\u4f1d\u5b50\u9451\u5b9a\u30b5\u30fc\u30d3\u30b9\u3092\u5229\u7528\u3059\u308b\u969b\u306f\u3001\u4fe1\u983c\u3067\u304d\u308b\u4f01\u696d\u3092\u9078\u3073\u3001\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u30dd\u30ea\u30b7\u30fc\u3092\u3088\u304f\u78ba\u8a8d\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-2. \u907a\u4f1d\u5b50\u5dee\u5225\u306e\u53ef\u80fd\u6027<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u3088\u3063\u3066\u3001\u751f\u547d\u4fdd\u967a\u306e\u52a0\u5165\u5236\u9650\u3084\u96c7\u7528\u306e\u5dee\u5225\u304c\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u5b9f\u969b\u306b\u30a2\u30e1\u30ea\u30ab\u3067\u306f\u300c\u907a\u4f1d\u60c5\u5831\u5dee\u5225\u7981\u6b62\u6cd5\uff08GINA\uff09\u300d\u304c\u5236\u5b9a\u3055\u308c\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u3088\u308b\u5dee\u5225\u3092\u7981\u6b62\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3-3. \u4e88\u6e2c\u60c5\u5831\u306e\u30d7\u30ec\u30c3\u30b7\u30e3\u30fc<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u304c\u5fc5\u305a\u3057\u3082\u672a\u6765\u3092\u6c7a\u5b9a\u3059\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u300c\u5c06\u6765\u75c5\u6c17\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u300d\u3068\u8a00\u308f\u308c\u305f\u5834\u5408\u3001\u305d\u308c\u304c\u5fc3\u7406\u7684\u30b9\u30c8\u30ec\u30b9\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u60c5\u5831\u306e\u53d7\u3051\u6b62\u3081\u65b9\u306b\u306f\u614e\u91cd\u306b\u306a\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u907a\u4f1d\u5b50\u9451\u5b9a\u30b5\u30fc\u30d3\u30b9\u306e\u9078\u3073\u65b9<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4-1. \u4fe1\u983c\u6027\u306e\u9ad8\u3044\u4f01\u696d\u3092\u9078\u3076<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u63d0\u4f9b\u3059\u308b\u4f01\u696d\u306f\u591a\u6570\u3042\u308a\u307e\u3059\u304c\u3001\u4ee5\u4e0b\u306e\u70b9\u3092\u78ba\u8a8d\u3057\u3066\u9078\u3076\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8a8d\u8a3c\u30fb\u898f\u5236\u306e\u6709\u7121<\/strong>\uff08\u4f8b\uff1aCLIA\u8a8d\u8a3c\u3001ISO\u8a8d\u8a3c\uff09<\/li>\n\n\n\n<li><strong>\u30c7\u30fc\u30bf\u306e\u53d6\u308a\u6271\u3044\u30dd\u30ea\u30b7\u30fc<\/strong><\/li>\n\n\n\n<li><strong>\u5229\u7528\u8005\u306e\u30ec\u30d3\u30e5\u30fc\u3084\u8a55\u5224<\/strong><\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4-2. \u30b3\u30b9\u30c8\u3068\u30b5\u30fc\u30d3\u30b9\u5185\u5bb9\u306e\u6bd4\u8f03<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u9451\u5b9a\u306e\u4fa1\u683c\u306f\u6570\u5343\u5186\u304b\u3089\u6570\u4e07\u5186\u3068\u5e45\u5e83\u304f\u3001\u63d0\u4f9b\u3055\u308c\u308b\u5206\u6790\u5185\u5bb9\u3082\u7570\u306a\u308a\u307e\u3059\u3002\u5065\u5eb7\u30ea\u30b9\u30af\u3001\u7956\u5148\u89e3\u6790\u3001\u85ac\u7406\u907a\u4f1d\u5b66\u306a\u3069\u3001\u5fc5\u8981\u306a\u60c5\u5831\u304c\u5f97\u3089\u308c\u308b\u30b5\u30fc\u30d3\u30b9\u3092\u9078\u3073\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1a\u4e3b\u8981\u306a\u907a\u4f1d\u5b50\u691c\u67fb\u30b5\u30fc\u30d3\u30b9<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u4f01\u696d\u540d<\/strong><\/td><td><strong>\u4e3b\u8981\u30b5\u30fc\u30d3\u30b9<\/strong><\/td><td><strong>\u4fa1\u683c\u5e2f<\/strong><\/td><\/tr><tr><td>23andMe<\/td><td>\u5065\u5eb7\u30ea\u30b9\u30af\u30fb\u7956\u5148\u89e3\u6790<\/td><td>\u7d0420,000\u5186\uff5e<\/td><\/tr><tr><td>MyHeritage DNA<\/td><td>\u7956\u5148\u89e3\u6790<\/td><td>\u7d0410,000\u5186\uff5e<\/td><\/tr><tr><td>GeneLife<\/td><td>\u5065\u5eb7\u30ea\u30b9\u30af\u30fb\u4f53\u8cea\u5206\u6790<\/td><td>\u7d0415,000\u5186\uff5e<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u672a\u6765\u306e\u5bb6\u5ead\u751f\u6d3b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/3760309_m-1024x683.jpg\" alt=\"\u3042\u3050\u3089\u3092\u304b\u3044\u3066\u8a71\u3059\u308b\u7236\u5a18\" class=\"wp-image-8000\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3760309_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3760309_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3760309_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3760309_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3760309_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5-1. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u304b\u3057\u305f\u30d8\u30eb\u30b9\u30b1\u30a2<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3092\u5065\u5eb7\u7ba1\u7406\u306b\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u5bb6\u65cf\u5168\u54e1\u304c\u3088\u308a\u9069\u5207\u306a\u533b\u7642\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u4e88\u9632\u533b\u7642\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u75c5\u6c17\u306e\u65e9\u671f\u767a\u898b\u3084\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u533b\u7642\u304c\u9032\u3080\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5-2. \u7cbe\u5bc6\u533b\u7642\u306e\u9032\u5316<\/strong><\/h3>\n\n\n\n<p>\u8fd1\u5e74\u3001\u300c\u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30fb\u30e1\u30c7\u30a3\u30b7\u30f3\uff08\u7cbe\u5bc6\u533b\u7642\uff09\u300d\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u500b\u3005\u306e\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u3082\u3068\u306b\u6700\u9069\u306a\u6cbb\u7642\u3092\u9078\u629e\u3059\u308b\u533b\u7642\u306e\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5-3. \u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306e\u672a\u6765<\/strong><\/h3>\n\n\n\n<p>CRISPR\u6280\u8853\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u5c06\u6765\u7684\u306b\u306f\u907a\u4f1d\u5b50\u3092\u7de8\u96c6\u3057\u3066\u75c5\u6c17\u3092\u4e88\u9632\u3059\u308b\u6642\u4ee3\u304c\u6765\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u6280\u8853\u306b\u306f\u502b\u7406\u7684\u306a\u8b70\u8ad6\u3082\u591a\u304f\u3001\u614e\u91cd\u306a\u8b70\u8ad6\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>[\u53c2\u8003\u6587\u732e]<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.nih.gov\/\">NIH\uff08\u7c73\u56fd\u56fd\u7acb\u885b\u751f\u7814\u7a76\u6240\uff09\u306b\u3088\u308b\u907a\u4f1d\u5b50\u7814\u7a76<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.genome.gov\/\">GINA\uff08\u907a\u4f1d\u60c5\u5831\u5dee\u5225\u7981\u6b62\u6cd5\uff09\u306b\u3064\u3044\u3066<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41591-021-01350-2\">\u7cbe\u5bc6\u533b\u7642\u306e\u6700\u65b0\u7814\u7a76<\/a><\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u907a\u4f1d\u5b50\u9451\u5b9a\u306e\u793e\u4f1a\u7684\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/30953618_m-1024x683.jpg\" alt=\"\u4f1a\u8b70\u30b7\u30fc\u30f3\" class=\"wp-image-8160\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30953618_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30953618_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30953618_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30953618_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30953618_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>6-1. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u4fdd\u967a\u696d\u754c<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u5229\u7528\u304c\u9032\u3080\u306b\u3064\u308c\u3066\u3001\u4fdd\u967a\u696d\u754c\u306b\u3082\u5f71\u97ff\u304c\u53ca\u3093\u3067\u3044\u307e\u3059\u3002\u751f\u547d\u4fdd\u967a\u3084\u533b\u7642\u4fdd\u967a\u3067\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u306b\u3088\u3063\u3066\u4fdd\u967a\u6599\u304c\u5909\u52d5\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u90e8\u306e\u56fd\u3067\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u4fdd\u967a\u4f1a\u793e\u304c\u5229\u7528\u3059\u308b\u3053\u3068\u3092\u7981\u6b62\u3059\u308b\u6cd5\u5f8b\u304c\u5236\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4f9d\u7136\u3068\u3057\u3066\u8ab2\u984c\u306f\u591a\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u30a2\u30e1\u30ea\u30ab\u3067\u306f\u300c\u907a\u4f1d\u60c5\u5831\u5dee\u5225\u7981\u6b62\u6cd5\uff08GINA\uff09\u300d\u306b\u3088\u308a\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u7406\u7531\u3068\u3057\u305f\u533b\u7642\u4fdd\u967a\u306e\u62d2\u5426\u304c\u7981\u6b62\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u751f\u547d\u4fdd\u967a\u3084\u9577\u671f\u4ecb\u8b77\u4fdd\u967a\u306b\u306f\u9069\u7528\u3055\u308c\u307e\u305b\u3093\u3002\u3053\u306e\u305f\u3081\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u53d7\u3051\u308b\u3053\u3068\u3067\u751f\u547d\u4fdd\u967a\u306e\u5951\u7d04\u304c\u4e0d\u5229\u306b\u306a\u308b\u53ef\u80fd\u6027\u3082\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>6-2. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u96c7\u7528<\/strong><\/h3>\n\n\n\n<p>\u4f01\u696d\u304c\u5f93\u696d\u54e1\u306e\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u53d6\u5f97\u3057\u3001\u305d\u308c\u3092\u96c7\u7528\u306e\u5224\u65ad\u57fa\u6e96\u3068\u3059\u308b\u3053\u3068\u306f\u502b\u7406\u7684\u306b\u554f\u984c\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u4e00\u90e8\u306e\u696d\u754c\u3067\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u5229\u7528\u3057\u3066\u8077\u5834\u306e\u5065\u5eb7\u7ba1\u7406\u3092\u5f37\u5316\u3059\u308b\u52d5\u304d\u3082\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u4eba\u304c\u7279\u5b9a\u306e\u5316\u5b66\u7269\u8cea\u306b\u5bfe\u3057\u3066\u904e\u654f\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u308b\u5834\u5408\u3001\u4f01\u696d\u304c\u305d\u306e\u60c5\u5831\u3092\u3082\u3068\u306b\u9069\u5207\u306a\u8077\u5834\u74b0\u5883\u3092\u6574\u3048\u308b\u3053\u3068\u306f\u7406\u306b\u304b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u308c\u304c\u63a1\u7528\u57fa\u6e96\u3068\u3057\u3066\u5229\u7528\u3055\u308c\u308b\u3068\u3001\u907a\u4f1d\u5b50\u5dee\u5225\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>6-3. \u907a\u4f1d\u5b50\u60c5\u5831\u306e\u5546\u696d\u5316<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u5e02\u5834\u306f\u6025\u901f\u306b\u62e1\u5927\u3057\u3066\u304a\u308a\u3001\u591a\u304f\u306e\u4f01\u696d\u304c\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u53ce\u96c6\u30fb\u6d3b\u7528\u3059\u308b\u30d3\u30b8\u30cd\u30b9\u3092\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u6d88\u8cbb\u8005\u306e\u907a\u4f1d\u5b50\u60c5\u5831\u304c\u3069\u306e\u3088\u3046\u306b\u5229\u7528\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u3001\u900f\u660e\u6027\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u533f\u540d\u5316\u3057\u3066\u533b\u85ac\u54c1\u958b\u767a\u306b\u6d3b\u7528\u3059\u308b\u30b1\u30fc\u30b9\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u306e\u30c7\u30fc\u30bf\u304c\u3069\u306e\u7a0b\u5ea6\u5b89\u5168\u306b\u7ba1\u7406\u3055\u308c\u3066\u3044\u308b\u304b\u306f\u3001\u5229\u7528\u8005\u306b\u3068\u3063\u3066\u5927\u304d\u306a\u95a2\u5fc3\u4e8b\u3067\u3059\u3002\u500b\u4eba\u306e\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u304c\u7b2c\u4e09\u8005\u306b\u8ca9\u58f2\u3055\u308c\u308b\u30ea\u30b9\u30af\u3092\u7406\u89e3\u3057\u3001\u614e\u91cd\u306b\u30b5\u30fc\u30d3\u30b9\u3092\u9078\u3076\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u907a\u4f1d\u5b50\u3068\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u6804\u990a\u5b66<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7-1. \u907a\u4f1d\u5b50\u3068\u98df\u4e8b\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u6804\u990a\u5b66\uff08\u6804\u990a\u907a\u4f1d\u5b66\uff09\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u3001\u7279\u5b9a\u306e\u6804\u990a\u7d20\u306e\u4ee3\u8b1d\u80fd\u529b\u3084\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u30ea\u30b9\u30af\u304c\u7570\u306a\u308b\u305f\u3081\u3001\u500b\u3005\u306b\u9069\u3057\u305f\u98df\u4e8b\u3092\u8a2d\u8a08\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001LCT\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3088\u308a\u4e73\u7cd6\u4e0d\u8010\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u4eba\u306f\u3001\u4e73\u88fd\u54c1\u3092\u63a7\u3048\u308b\u3053\u3068\u3067\u6d88\u5316\u4e0d\u826f\u3092\u9632\u3050\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u307e\u305f\u3001FTO\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u3042\u308b\u4eba\u306f\u3001\u80a5\u6e80\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u50be\u5411\u304c\u3042\u308a\u3001\u9069\u5207\u306a\u98df\u4e8b\u7ba1\u7406\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7-2. \u907a\u4f1d\u5b50\u30d9\u30fc\u30b9\u306e\u30c0\u30a4\u30a8\u30c3\u30c8<\/strong><\/h3>\n\n\n\n<p>\u4e00\u822c\u7684\u306a\u30c0\u30a4\u30a8\u30c3\u30c8\u65b9\u6cd5\u306f\u4e07\u4eba\u5411\u3051\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u3082\u3068\u306b\u500b\u5225\u306b\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u6e1b\u91cf\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001PPARG\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u4f4e\u8102\u80aa\u98df\u3088\u308a\u3082\u4f4e\u70ad\u6c34\u5316\u7269\u98df\u306e\u307b\u3046\u304c\u6e1b\u91cf\u52b9\u679c\u304c\u9ad8\u3044\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u306b\u57fa\u3065\u3044\u305f\u98df\u4e8b\u30d7\u30e9\u30f3\u3092\u63a1\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u7387\u7684\u306b\u5065\u5eb7\u7ba1\u7406\u3092\u884c\u3046\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u907a\u4f1d\u5b50\u3068\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/3882305_m-1024x683.jpg\" alt=\"\u30e9\u30f3\u30cb\u30f3\u30b0\u30fb\u30b8\u30e7\u30ae\u30f3\u30b0\u30fb\u30a6\u30a9\u30fc\u30ad\u30f3\u30b0\u3059\u308b\u7537\u5973\" class=\"wp-image-7869\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3882305_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3882305_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3882305_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3882305_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3882305_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>8-1. \u907a\u4f1d\u5b50\u3068\u7b4b\u8089\u306e\u7a2e\u985e<\/strong><\/h3>\n\n\n\n<p>\u7b4b\u8089\u306b\u306f\u901f\u7b4b\u3068\u9045\u7b4b\u304c\u3042\u308a\u3001\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u3069\u3061\u3089\u304c\u512a\u52e2\u304b\u304c\u6c7a\u307e\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001ACTN3\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3088\u3063\u3066\u3001\u901f\u7b4b\u306e\u767a\u9054\u304c\u4fc3\u9032\u3055\u308c\u308b\u4eba\u3068\u305d\u3046\u3067\u306a\u3044\u4eba\u304c\u5b58\u5728\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u901f\u7b4b\u578b\uff08ACTN3 RR\u578b\uff09<\/strong>\uff1a\u77ed\u8ddd\u96e2\u8d70\u3084\u91cd\u91cf\u6319\u3052\u306a\u3069\u306e\u30d1\u30ef\u30fc\u30b9\u30dd\u30fc\u30c4\u306b\u5411\u3044\u3066\u3044\u308b<\/li>\n\n\n\n<li><strong>\u9045\u7b4b\u578b\uff08ACTN3 XX\u578b\uff09<\/strong>\uff1a\u30de\u30e9\u30bd\u30f3\u3084\u30c8\u30e9\u30a4\u30a2\u30b9\u30ed\u30f3\u306a\u3069\u306e\u6301\u4e45\u7cfb\u30b9\u30dd\u30fc\u30c4\u306b\u5411\u3044\u3066\u3044\u308b<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306a\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30b9\u30dd\u30fc\u30c4\u9078\u624b\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u8a08\u753b\u3092\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>8-2. \u907a\u4f1d\u5b50\u3068\u6301\u4e45\u529b<\/strong><\/h3>\n\n\n\n<p>EPO\u907a\u4f1d\u5b50\u306f\u8d64\u8840\u7403\u306e\u751f\u6210\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306b\u3088\u3063\u3066\u9178\u7d20\u904b\u642c\u80fd\u529b\u304c\u5909\u308f\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u3088\u308a\u9ad8\u3044\u6301\u4e45\u529b\u3092\u767a\u63ee\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30b9\u30dd\u30fc\u30c4\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u6700\u5927\u5316\u3059\u308b\u305f\u3081\u306b\u3001\u81ea\u5206\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u7406\u89e3\u3057\u3001\u305d\u308c\u306b\u5408\u308f\u305b\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u884c\u3046\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306e\u9032\u6b69\u3068\u8ab2\u984c<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>9-1. CRISPR\u6280\u8853\u306e\u53ef\u80fd\u6027<\/strong><\/h3>\n\n\n\n<p>CRISPR-Cas9\u6280\u8853\u306e\u767b\u5834\u306b\u3088\u308a\u3001\u907a\u4f1d\u5b50\u7de8\u96c6\u304c\u6025\u901f\u306b\u9032\u5316\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u6280\u8853\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u75c5\u3092\u4e88\u9632\u3057\u305f\u308a\u3001\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u3092\u958b\u767a\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u938c\u72b6\u8d64\u8840\u7403\u75c7\u3084\u56a2\u80de\u6027\u7dda\u7dad\u75c7\u306a\u3069\u306e\u907a\u4f1d\u75c5\u306f\u3001CRISPR\u6280\u8853\u3092\u7528\u3044\u305f\u6cbb\u7642\u304c\u7814\u7a76\u6bb5\u968e\u306b\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u30d2\u30c8\u306e\u907a\u4f1d\u5b50\u3092\u7de8\u96c6\u3059\u308b\u3053\u3068\u306e\u502b\u7406\u7684\u554f\u984c\u3082\u5927\u304d\u306a\u8b70\u8ad6\u306e\u7684\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>9-2. \u502b\u7406\u7684\u306a\u554f\u984c<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u304c\u9032\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u5c06\u6765\u7684\u306b\u306f\u300c\u30c7\u30b6\u30a4\u30ca\u30fc\u30d9\u30d3\u30fc\u300d\u306e\u8a95\u751f\u304c\u53ef\u80fd\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3053\u308c\u306f\u3001\u89aa\u304c\u5b50\u3069\u3082\u306e\u907a\u4f1d\u5b50\u3092\u610f\u56f3\u7684\u306b\u6539\u5909\u3057\u3001\u671b\u307e\u3057\u3044\u7279\u6027\u3092\u6301\u305f\u305b\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306a\u6280\u8853\u304c\u4e00\u822c\u5316\u3059\u308b\u3068\u3001\u907a\u4f1d\u5b50\u306e\u300c\u512a\u52a3\u300d\u306b\u3088\u308b\u793e\u4f1a\u7684\u683c\u5dee\u304c\u751f\u307e\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u502b\u7406\u7684\u306a\u89b3\u70b9\u304b\u3089\u614e\u91cd\u306a\u8b70\u8ad6\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>9-3. \u907a\u4f1d\u5b50\u7de8\u96c6\u3068\u6cd5\u898f\u5236<\/strong><\/h3>\n\n\n\n<p>\u73fe\u5728\u3001\u591a\u304f\u306e\u56fd\u3067\u306f\u30d2\u30c8\u306e\u751f\u6b96\u7d30\u80de\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u7de8\u96c6\u3092\u7981\u6b62\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u4e2d\u56fd\u3067\u306f\u3059\u3067\u306b\u907a\u4f1d\u5b50\u7de8\u96c6\u3092\u65bd\u3057\u305f\u53cc\u5b50\u306e\u8d64\u3061\u3083\u3093\u304c\u8a95\u751f\u3057\u3001\u4e16\u754c\u7684\u306a\u8ad6\u4e89\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u79d1\u5b66\u306e\u9032\u6b69\u3068\u502b\u7406\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u3069\u3046\u53d6\u308b\u304b\u306f\u3001\u4eca\u5f8c\u306e\u907a\u4f1d\u5b50\u7814\u7a76\u306b\u304a\u3051\u308b\u5927\u304d\u306a\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>[\u8ffd\u52a0\u306e\u53c2\u8003\u6587\u732e]<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.nature.com\/ng\/\">Nature Genetics\u306e\u907a\u4f1d\u5b50\u7814\u7a76<\/a><\/li>\n\n\n\n<li>\u907a\u4f1d\u5b50\u3068\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u95a2\u3059\u308b\u7814\u7a76<\/li>\n\n\n\n<li>CRISPR\u6280\u8853\u3068\u502b\u7406\u7684\u8ab2\u984c<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u907a\u4f1d\u5b50\u3068\u7cbe\u795e\u7684\u5065\u5eb7\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/31243181_m-1024x683.jpg\" alt=\"\u982d\u3092\u62b1\u3048\u308b\u5973\u6027\" class=\"wp-image-8703\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31243181_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31243181_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31243181_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31243181_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31243181_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>10-1. \u907a\u4f1d\u5b50\u3068\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9<\/strong><\/h3>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u3068\u7cbe\u795e\u75be\u60a3\u306e\u95a2\u9023\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3046\u3064\u75c5\u3084\u4e0d\u5b89\u969c\u5bb3\u3001\u7d71\u5408\u5931\u8abf\u75c7\u306a\u3069\u306e\u7cbe\u795e\u75be\u60a3\u306f\u3001\u74b0\u5883\u8981\u56e0\u3068\u907a\u4f1d\u7684\u8981\u56e0\u306e\u4e21\u65b9\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1a5-HTTLPR\u907a\u4f1d\u5b50\u3068\u3046\u3064\u75c5<\/strong><strong><br><\/strong> 5-HTTLPR\u907a\u4f1d\u5b50\u306f\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u518d\u53d6\u308a\u8fbc\u307f\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3057\u3066\u654f\u611f\u306b\u306a\u308a\u3001\u3046\u3064\u75c5\u3092\u767a\u75c7\u3057\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>10-2. \u907a\u4f1d\u5b50\u3068\u8a8d\u77e5\u6a5f\u80fd<\/strong><\/h3>\n\n\n\n<p>\u77e5\u80fd\u3084\u8a18\u61b6\u529b\u306b\u3082\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001BDNF\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09\u907a\u4f1d\u5b50\u306f\u3001\u8a18\u61b6\u306e\u5f62\u6210\u3084\u795e\u7d4c\u7d30\u80de\u306e\u6210\u9577\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u5b66\u7fd2\u80fd\u529b\u304c\u9ad8\u3044\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>10-3. \u907a\u4f1d\u5b50\u3068\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u7cbe\u795e\u533b\u7642<\/strong><\/h3>\n\n\n\n<p>\u5c06\u6765\u7684\u306b\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u3082\u3068\u306b\u500b\u4eba\u306b\u6700\u9069\u306a\u7cbe\u795e\u533b\u7642\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u85ac\u7406\u907a\u4f1d\u5b66\u3092\u5229\u7528\u3059\u308c\u3070\u3001\u6297\u3046\u3064\u85ac\u3084\u6297\u7cbe\u795e\u75c5\u85ac\u306e\u52b9\u679c\u3092\u4e8b\u524d\u306b\u4e88\u6e2c\u3057\u3001\u526f\u4f5c\u7528\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. \u907a\u4f1d\u5b50\u3068\u5bff\u547d\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>11-1. \u907a\u4f1d\u5b50\u3068\u9577\u5bff<\/strong><\/h3>\n\n\n\n<p>\u9577\u5bff\u306b\u95a2\u4fc2\u3059\u308b\u907a\u4f1d\u5b50\u304c\u3044\u304f\u3064\u304b\u7279\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001FOXO3\u907a\u4f1d\u5b50\u306f\u3001\u5bff\u547d\u3092\u5ef6\u3070\u3059\u50cd\u304d\u3092\u6301\u3064\u3068\u3055\u308c\u3001\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f100\u6b73\u4ee5\u4e0a\u751f\u304d\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001SIRT1\u907a\u4f1d\u5b50\u306f\u7d30\u80de\u306e\u8001\u5316\u3092\u9045\u3089\u305b\u308b\u5f79\u5272\u3092\u6301\u3061\u3001\u9577\u5bff\u3068\u6df1\u304f\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306f\u30ab\u30ed\u30ea\u30fc\u5236\u9650\u306b\u3088\u3063\u3066\u6d3b\u6027\u5316\u3055\u308c\u308b\u305f\u3081\u3001\u9069\u5ea6\u306a\u98df\u4e8b\u5236\u9650\u304c\u5bff\u547d\u3092\u5ef6\u3070\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>11-2. \u907a\u4f1d\u5b50\u3068\u8001\u5316\u30d7\u30ed\u30bb\u30b9<\/strong><\/h3>\n\n\n\n<p>\u8001\u5316\u306f\u3001\u7d30\u80de\u306eDNA\u640d\u50b7\u3084\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u84c4\u7a4d\u306b\u3088\u3063\u3066\u9032\u884c\u3057\u307e\u3059\u3002\u907a\u4f1d\u7684\u8981\u56e0\u304c\u8001\u5316\u306e\u30b9\u30d4\u30fc\u30c9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304a\u308a\u3001\u30c6\u30ed\u30e1\u30a2\u306e\u9577\u3055\u3082\u91cd\u8981\u306a\u6307\u6a19\u306e\u4e00\u3064\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30c6\u30ed\u30e1\u30a2\u3068\u306f\u3001\u67d3\u8272\u4f53\u306e\u672b\u7aef\u90e8\u5206\u306e\u3053\u3068\u3067\u3001\u7d30\u80de\u5206\u88c2\u306e\u305f\u3073\u306b\u77ed\u304f\u306a\u308a\u307e\u3059\u3002TERT\u907a\u4f1d\u5b50\u304c\u6d3b\u6027\u5316\u3059\u308b\u3068\u3001\u30c6\u30ed\u30e1\u30a2\u306e\u77ed\u7e2e\u3092\u6291\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u7d50\u679c\u3068\u3057\u3066\u8001\u5316\u306e\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>11-3. \u907a\u4f1d\u5b50\u3068\u751f\u6d3b\u7fd2\u6163\u306e\u76f8\u4e92\u4f5c\u7528<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u7684\u306b\u9577\u5bff\u306e\u7d20\u8cea\u3092\u6301\u3064\u4eba\u3067\u3082\u3001\u4e0d\u5065\u5eb7\u306a\u751f\u6d3b\u7fd2\u6163\u3092\u7d9a\u3051\u308c\u3070\u5bff\u547d\u306f\u7e2e\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u9006\u306b\u3001\u907a\u4f1d\u7684\u306b\u75c5\u6c17\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u4eba\u3067\u3082\u3001\u9069\u5207\u306a\u751f\u6d3b\u7fd2\u6163\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u3067\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u3068\u74b0\u5883\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u7406\u89e3\u3057\u3001\u9069\u5207\u306a\u751f\u6d3b\u7fd2\u6163\u3092\u9078\u629e\u3059\u308b\u3053\u3068\u304c\u5065\u5eb7\u5bff\u547d\u3092\u5ef6\u3070\u3059\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>12. \u907a\u4f1d\u5b50\u3068\u7761\u7720\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/32032150_m-1024x683.jpg\" alt=\"\u90e8\u5c4b\u3067\u5bdd\u308b\u82e5\u3044\u5973\u6027\" class=\"wp-image-8997\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32032150_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32032150_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32032150_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32032150_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/32032150_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>12-1. \u907a\u4f1d\u5b50\u3068\u7761\u7720\u30d1\u30bf\u30fc\u30f3<\/strong><\/h3>\n\n\n\n<p>\u7761\u7720\u306e\u8cea\u3084\u5fc5\u8981\u306a\u7761\u7720\u6642\u9593\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u305d\u308c\u306b\u306f\u907a\u4f1d\u5b50\u304c\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001DEC2\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u901a\u5e38\u3088\u308a\u3082\u77ed\u3044\u7761\u7720\u6642\u9593\u3067\u5341\u5206\u306a\u4f11\u606f\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u300c\u30b7\u30e7\u30fc\u30c8\u30b9\u30ea\u30fc\u30d1\u30fc\u300d\u306e\u7279\u5fb4\u3092\u6301\u3064\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>12-2. \u907a\u4f1d\u5b50\u3068\u6982\u65e5\u30ea\u30ba\u30e0<\/strong><\/h3>\n\n\n\n<p>\u4f53\u5185\u6642\u8a08\uff08\u30b5\u30fc\u30ab\u30c7\u30a3\u30a2\u30f3\u30ea\u30ba\u30e0\uff09\u306f\u3001\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u8abf\u7bc0\u3055\u308c\u3066\u3044\u307e\u3059\u3002PER3\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306b\u3088\u3063\u3066\u3001\u671d\u578b\u30fb\u591c\u578b\u306e\u50be\u5411\u304c\u6c7a\u307e\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PER3\u9577\u3044\u30d0\u30ea\u30a2\u30f3\u30c8<\/strong> \u2192 \u671d\u578b\u306b\u306a\u308a\u3084\u3059\u3044<\/li>\n\n\n\n<li><strong>PER3\u77ed\u3044\u30d0\u30ea\u30a2\u30f3\u30c8<\/strong> \u2192 \u591c\u578b\u306b\u306a\u308a\u3084\u3059\u3044<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u60c5\u5831\u3092\u3082\u3068\u306b\u3001\u81ea\u5206\u306b\u6700\u9069\u306a\u7761\u7720\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u3092\u8a2d\u8a08\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>12-3. \u907a\u4f1d\u5b50\u3068\u7761\u7720\u969c\u5bb3<\/strong><\/h3>\n\n\n\n<p>\u4e0d\u7720\u75c7\u3084\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u306a\u3069\u306e\u7761\u7720\u969c\u5bb3\u306b\u3082\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001HLA-DQB1\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3001\u30ca\u30eb\u30b3\u30ec\u30d7\u30b7\u30fc\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u7761\u7720\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u3092\u4e8b\u524d\u306b\u628a\u63e1\u3057\u3001\u65e9\u671f\u306e\u5bfe\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>13. \u907a\u4f1d\u5b50\u3068\u514d\u75ab\u30b7\u30b9\u30c6\u30e0<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>13-1. \u907a\u4f1d\u5b50\u3068\u611f\u67d3\u75c7\u30ea\u30b9\u30af<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306f\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u306e\u50cd\u304d\u306b\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001HLA\u907a\u4f1d\u5b50\u7fa4\u306f\u3001\u514d\u75ab\u5fdc\u7b54\u306e\u8abf\u6574\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u3042\u308b\u3068\u30a6\u30a4\u30eb\u30b9\u3084\u7d30\u83cc\u306b\u5bfe\u3059\u308b\u62b5\u6297\u529b\u304c\u5909\u308f\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1aCCR5\u907a\u4f1d\u5b50\u3068HIV\u8010\u6027<\/strong><strong><br><\/strong> CCR5\u907a\u4f1d\u5b50\u306e\u5909\u7570\uff08CCR5-\u039432\u5909\u7570\uff09\u3092\u6301\u3064\u4eba\u306f\u3001HIV\uff08\u30d2\u30c8\u514d\u75ab\u4e0d\u5168\u30a6\u30a4\u30eb\u30b9\uff09\u306b\u611f\u67d3\u3057\u306b\u304f\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u30a6\u30a4\u30eb\u30b9\u304c\u7d30\u80de\u306b\u4fb5\u5165\u3059\u308b\u305f\u3081\u306e\u53d7\u5bb9\u4f53\u304c\u4f5c\u3089\u308c\u306a\u304f\u306a\u308b\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>13-2. \u907a\u4f1d\u5b50\u3068\u30a2\u30ec\u30eb\u30ae\u30fc<\/strong><\/h3>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u306b\u3082\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001IL4\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u82b1\u7c89\u75c7\u3084\u5598\u606f\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>13-3. \u907a\u4f1d\u5b50\u3068\u81ea\u5df1\u514d\u75ab\u75be\u60a3<\/strong><\/h3>\n\n\n\n<p>\u81ea\u5df1\u514d\u75ab\u75be\u60a3\uff08\u4f8b\uff1a\u30ea\u30a6\u30de\u30c1\u30011\u578b\u7cd6\u5c3f\u75c5\u3001\u30af\u30ed\u30fc\u30f3\u75c5\uff09\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u8981\u56e0\u304c\u8907\u96d1\u306b\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u5b9a\u306eHLA\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u3042\u308b\u3068\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u4e8b\u524d\u306b\u628a\u63e1\u3057\u3001\u65e9\u671f\u306e\u4e88\u9632\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>[\u8ffd\u52a0\u306e\u53c2\u8003\u6587\u732e]<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41586-019-1641-4\">\u907a\u4f1d\u5b50\u3068\u7761\u7720\u306b\u95a2\u3059\u308b\u7814\u7a76<\/a><\/li>\n\n\n\n<li>FOXO3\u907a\u4f1d\u5b50\u3068\u9577\u5bff\u306e\u95a2\u4fc2<\/li>\n\n\n\n<li>\u514d\u75ab\u907a\u4f1d\u5b66\u306e\u6700\u65b0\u7814\u7a76<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>14. \u907a\u4f1d\u5b50\u3068\u500b\u4eba\u306e\u884c\u52d5\u7279\u6027<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/4440226_m-1024x683.jpg\" alt=\"\u30de\u30c3\u30c8\u4e0a\u3067\u904a\u3076\u5e7c\u5150\u305f\u3061\" class=\"wp-image-9077\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4440226_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4440226_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4440226_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4440226_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4440226_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>14-1. \u907a\u4f1d\u5b50\u3068\u6027\u683c<\/strong><\/h3>\n\n\n\n<p>\u6027\u683c\u306f\u74b0\u5883\u8981\u56e0\u306b\u3088\u3063\u3066\u5f62\u6210\u3055\u308c\u308b\u90e8\u5206\u304c\u5927\u304d\u3044\u3067\u3059\u304c\u3001\u907a\u4f1d\u7684\u8981\u56e0\u3082\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1aDRD4\u907a\u4f1d\u5b50\u3068\u5192\u967a\u5fc3<\/strong><strong><br><\/strong> DRD4\u907a\u4f1d\u5b50\u306f\u30c9\u30fc\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u305d\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306e\u4e00\u3064\u3067\u3042\u308b7R\u30a2\u30ec\u30eb\u304c\u3042\u308b\u4eba\u306f\u3001\u5192\u967a\u5fc3\u304c\u5f37\u304f\u3001\u65b0\u3057\u3044\u7d4c\u9a13\u3092\u6c42\u3081\u308b\u50be\u5411\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001OXT\u907a\u4f1d\u5b50\uff08\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\uff09\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306b\u3088\u3063\u3066\u3001\u5171\u611f\u529b\u3084\u793e\u4ea4\u6027\u304c\u5909\u308f\u308b\u53ef\u80fd\u6027\u3082\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>14-2. \u907a\u4f1d\u5b50\u3068\u4f9d\u5b58\u75c7<\/strong><\/h3>\n\n\n\n<p>\u30a2\u30eb\u30b3\u30fc\u30eb\u4f9d\u5b58\u75c7\u3084\u85ac\u7269\u4f9d\u5b58\u75c7\u306b\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1aALDH2\u907a\u4f1d\u5b50\u3068\u30a2\u30eb\u30b3\u30fc\u30eb\u8010\u6027<\/strong><strong><br><\/strong> ALDH2\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u3092\u5206\u89e3\u3059\u308b\u80fd\u529b\u304c\u4f4e\u304f\u3001\u98f2\u9152\u5f8c\u306b\u9854\u304c\u8d64\u304f\u306a\u308a\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u9055\u3044\u306b\u3088\u3063\u3066\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u4f9d\u5b58\u75c7\u306e\u30ea\u30b9\u30af\u304c\u5909\u308f\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001CHRNA5\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3001\u30cb\u30b3\u30c1\u30f3\u4f9d\u5b58\u75c7\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>14-3. \u907a\u4f1d\u5b50\u3068\u30b9\u30c8\u30ec\u30b9\u8010\u6027<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u8010\u6027\u3082\u907a\u4f1d\u7684\u306a\u5f71\u97ff\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1aCOMT\u907a\u4f1d\u5b50\u3068\u30b9\u30c8\u30ec\u30b9\u53cd\u5fdc<\/strong><strong><br><\/strong> COMT\u907a\u4f1d\u5b50\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u306e\u4e00\u3064\u3067\u3042\u308b\u30ab\u30c6\u30b3\u30fc\u30eb\u30a2\u30df\u30f3\u3092\u5206\u89e3\u3059\u308b\u9175\u7d20\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306b\u3088\u3063\u3066\u30b9\u30c8\u30ec\u30b9\u3078\u306e\u53cd\u5fdc\u304c\u7570\u306a\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Met\/Met\u578b<\/strong> \u2192 \u30b9\u30c8\u30ec\u30b9\u306b\u654f\u611f<\/li>\n\n\n\n<li><strong>Val\/Val\u578b<\/strong> \u2192 \u30b9\u30c8\u30ec\u30b9\u8010\u6027\u304c\u9ad8\u3044<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30b9\u30c8\u30ec\u30b9\u30de\u30cd\u30b8\u30e1\u30f3\u30c8\u306e\u65b9\u6cd5\u3092\u500b\u5225\u306b\u8abf\u6574\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>15. \u907a\u4f1d\u5b50\u3068\u604b\u611b\u30fb\u7d50\u5a5a<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>15-1. \u907a\u4f1d\u5b50\u3068\u30d1\u30fc\u30c8\u30ca\u30fc\u9078\u3073<\/strong><\/h3>\n\n\n\n<p>\u604b\u611b\u3084\u7d50\u5a5a\u306b\u304a\u3044\u3066\u3082\u3001\u907a\u4f1d\u5b50\u304c\u4e00\u5b9a\u306e\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u4f8b\uff1aMHC\u907a\u4f1d\u5b50\u3068\u76f8\u6027<\/strong><strong><br><\/strong> MHC\uff08\u4e3b\u8981\u7d44\u7e54\u9069\u5408\u907a\u4f1d\u5b50\u8907\u5408\u4f53\uff09\u306f\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u7fa4\u3067\u3059\u304c\u3001\u7570\u306a\u308bMHC\u907a\u4f1d\u5b50\u3092\u6301\u3064\u7570\u6027\u306b\u5bfe\u3057\u3066\u3088\u308a\u5f37\u3044\u9b45\u529b\u3092\u611f\u3058\u308b\u50be\u5411\u304c\u3042\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u907a\u4f1d\u7684\u306b\u591a\u69d8\u306a\u5b50\u5b6b\u3092\u6b8b\u3059\u305f\u3081\u306e\u9032\u5316\u7684\u306a\u9069\u5fdc\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>15-2. \u907a\u4f1d\u5b50\u3068\u604b\u611b\u30db\u30eb\u30e2\u30f3<\/strong><\/h3>\n\n\n\n<p>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\uff08\u611b\u60c5\u30db\u30eb\u30e2\u30f3\uff09\u3084\u30d0\u30bd\u30d7\u30ec\u30c3\u30b7\u30f3\uff08\u7d46\u30db\u30eb\u30e2\u30f3\uff09\u306e\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\u3082\u3001\u604b\u611b\u95a2\u4fc2\u306e\u7dad\u6301\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001OXTR\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306b\u3088\u3063\u3066\u3001\u89aa\u5bc6\u306a\u95a2\u4fc2\u3092\u7bc9\u304d\u3084\u3059\u3044\u304b\u3069\u3046\u304b\u304c\u7570\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001AVPR1A\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3001\u7537\u6027\u306e\u6d6e\u6c17\u50be\u5411\u3068\u95a2\u9023\u304c\u3042\u308b\u3068\u3044\u3046\u7814\u7a76\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>15-3. \u907a\u4f1d\u5b50\u3068\u7d50\u5a5a\u6e80\u8db3\u5ea6<\/strong><\/h3>\n\n\n\n<p>\u4e00\u90e8\u306e\u7814\u7a76\u3067\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u7d50\u5a5a\u306e\u6e80\u8db3\u5ea6\u3084\u96e2\u5a5a\u7387\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u907a\u4f1d\u5b50\uff085-HTTLPR\uff09\u306e\u77ed\u3044\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u604b\u611b\u95a2\u4fc2\u306e\u4e0d\u5b89\u5b9a\u3055\u3092\u611f\u3058\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>16. \u907a\u4f1d\u5b50\u3068\u72af\u7f6a\u884c\u52d5<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/27608468_m-1024x683.jpg\" alt=\"\u30b5\u30a4\u30d0\u30fc\u72af\u7f6a\u3000\u30a4\u30e1\u30fc\u30b8\" class=\"wp-image-3520\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/27608468_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/27608468_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/27608468_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/27608468_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/27608468_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>16-1. MAOA\u907a\u4f1d\u5b50\u3068\u653b\u6483\u6027<\/strong><\/h3>\n\n\n\n<p>MAOA\u907a\u4f1d\u5b50\u306f\u300c\u6226\u58eb\u907a\u4f1d\u5b50\u300d\u3068\u3082\u547c\u3070\u308c\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u3084\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u5206\u89e3\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002MAOA\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\uff08\u4f4e\u6d3b\u6027\u578b\uff09\u3092\u6301\u3064\u4eba\u306f\u3001\u5e7c\u5c11\u671f\u306b\u8650\u5f85\u3092\u53d7\u3051\u305f\u5834\u5408\u3001\u6210\u4eba\u5f8c\u306b\u653b\u6483\u7684\u306a\u884c\u52d5\u3092\u53d6\u308a\u3084\u3059\u304f\u306a\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u907a\u4f1d\u5b50\u3060\u3051\u3067\u72af\u7f6a\u884c\u52d5\u304c\u6c7a\u307e\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u74b0\u5883\u8981\u56e0\u304c\u5927\u304d\u304f\u5f71\u97ff\u3059\u308b\u3053\u3068\u3082\u91cd\u8981\u306a\u30dd\u30a4\u30f3\u30c8\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>16-2. \u907a\u4f1d\u5b50\u3068\u9053\u5fb3\u7684\u5224\u65ad<\/strong><\/h3>\n\n\n\n<p>\u9053\u5fb3\u7684\u306a\u5224\u65ad\u306b\u3082\u3001\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001AVPR1A\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u3042\u308b\u3068\u3001\u4ed6\u8005\u3078\u306e\u5171\u611f\u3084\u793e\u4f1a\u7684\u306a\u5354\u8abf\u6027\u304c\u5909\u308f\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u3084\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u306e\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\u3082\u3001\u4eba\u9593\u306e\u5584\u60aa\u306e\u5224\u65ad\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>16-3. \u907a\u4f1d\u5b50\u3068\u885d\u52d5\u6027<\/strong><\/h3>\n\n\n\n<p>\u885d\u52d5\u7684\u306a\u884c\u52d5\u3092\u3068\u308a\u3084\u3059\u3044\u304b\u3069\u3046\u304b\u3082\u3001\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u4e00\u5b9a\u306e\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001DRD2\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u5831\u916c\u3092\u6c42\u3081\u308b\u884c\u52d5\u304c\u5f37\u304f\u3001\u30ae\u30e3\u30f3\u30d6\u30eb\u4f9d\u5b58\u3084\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u884c\u52d5\u3092\u53d6\u308a\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u9451\u5b9a\u306f\u3001\u500b\u4eba\u306e\u5065\u5eb7\u7ba1\u7406\u3001\u5bb6\u7cfb\u306e\u7406\u89e3\u3001\u9069\u5207\u306a\u98df\u4e8b\u3084\u904b\u52d5\u3001\u7cbe\u795e\u7684\u5065\u5eb7\u306e\u30b5\u30dd\u30fc\u30c8\u3001\u3055\u3089\u306b\u306f\u604b\u611b\u3084\u884c\u52d5\u7279\u6027\u306e\u5206\u6790\u306a\u3069\u3001\u591a\u5c90\u306b\u308f\u305f\u308b\u5206\u91ce\u3067\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u79d1\u5b66\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u533b\u7642\u3084\u6804\u990a\u5b66\u304c\u767a\u5c55\u3057\u3001\u500b\u3005\u306b\u6700\u9069\u306a\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3092\u9078\u629e\u3067\u304d\u308b\u6642\u4ee3\u304c\u5230\u6765\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u53d6\u308a\u6271\u3044\u306b\u306f\u614e\u91cd\u306a\u59ff\u52e2\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u306e\u4fdd\u8b77\u3001\u907a\u4f1d\u5b50\u5dee\u5225\u306e\u30ea\u30b9\u30af\u3001\u502b\u7406\u7684\u306a\u554f\u984c\u306a\u3069\u3001\u6280\u8853\u306e\u9032\u6b69\u3068\u3068\u3082\u306b\u65b0\u305f\u306a\u8ab2\u984c\u3082\u6d6e\u304b\u3073\u4e0a\u304c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u79c1\u305f\u3061\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u5358\u306a\u308b\u30c7\u30fc\u30bf\u3068\u3057\u3066\u6349\u3048\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u305d\u308c\u3092\u3069\u306e\u3088\u3046\u306b\u6d3b\u7528\u3057\u3001\u3069\u306e\u3088\u3046\u306b\u5b88\u308b\u304b\u3092\u8003\u3048\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u672a\u6765\u306e\u5bb6\u5ead\u3084\u793e\u4f1a\u306b\u304a\u3044\u3066\u3001\u907a\u4f1d\u5b50\u9451\u5b9a\u306e\u6069\u6075\u3092\u6700\u5927\u9650\u306b\u751f\u304b\u3059\u305f\u3081\u306b\u306f\u3001\u79d1\u5b66\u7684\u306a\u77e5\u8b58\u3092\u6301\u3061\u3001\u9069\u5207\u306a\u9078\u629e\u3092\u3059\u308b\u3053\u3068\u304c\u6c42\u3081\u3089\u308c\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n<div 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