{"id":573,"date":"2024-11-26T03:24:12","date_gmt":"2024-11-26T03:24:12","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=573"},"modified":"2025-03-06T06:37:33","modified_gmt":"2025-03-06T06:37:33","slug":"genetic-fitness-training-optimization","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/genetic-fitness-training-optimization\/","title":{"rendered":"\u907a\u4f1d\u5b50\u691c\u67fb\u3067\u308f\u304b\u308b\u904b\u52d5\u9069\u6027\u3068\u6700\u9069\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5"},"content":{"rendered":"\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u904b\u52d5\u9069\u6027\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u30b9\u30dd\u30fc\u30c4\u3084\u30d5\u30a3\u30c3\u30c8\u30cd\u30b9\u306e\u5206\u91ce\u3067\u306f\u3001\u300c\u751f\u307e\u308c\u3064\u304d\u904b\u52d5\u304c\u5f97\u610f\u306a\u4eba\u300d\u3068\u300c\u52aa\u529b\u3057\u3066\u3082\u306a\u304b\u306a\u304b\u6210\u679c\u304c\u51fa\u306b\u304f\u3044\u4eba\u300d\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u304c\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u9055\u3044\u306b\u306f\u3001\u74b0\u5883\u8981\u56e0\u3060\u3051\u3067\u306a\u304f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u3063\u3066\u3001\u7b4b\u8089\u306e\u7279\u6027\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3001\u6301\u4e45\u529b\u3068\u77ac\u767a\u529b\u306e\u30d0\u30e9\u30f3\u30b9\u3001\u56de\u5fa9\u529b\u306e\u9055\u3044\u306a\u3069\u304c\u79d1\u5b66\u7684\u306b\u5206\u6790\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u500b\u3005\u306b\u9069\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3092\u9078\u629e\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u904b\u52d5\u9069\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u4e3b\u306a\u907a\u4f1d\u5b50<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3067\u306f\u3001\u904b\u52d5\u80fd\u529b\u3084\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u52b9\u679c\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3044\u304f\u3064\u304b\u306e\u91cd\u8981\u306a\u907a\u4f1d\u5b50\u3092\u89e3\u6790\u3057\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u7279\u306b\u5f71\u97ff\u304c\u5927\u304d\u3044\u3068\u3055\u308c\u308b\u907a\u4f1d\u5b50\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2.1. ACTN3\u907a\u4f1d\u5b50\uff08\u901f\u7b4b\u3068\u6301\u4e45\u529b\u306e\u7279\u6027\uff09<\/strong><\/h3>\n\n\n\n<p>ACTN3\u907a\u4f1d\u5b50\u306f\u300c\u03b1-\u30a2\u30af\u30c1\u30cb\u30f33\u300d\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3001\u901f\u7b4b\u306e\u50cd\u304d\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306b\u306f\u4ee5\u4e0b\u306e3\u3064\u306e\u30bf\u30a4\u30d7\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>RR\u578b<\/strong>\uff1a\u901f\u7b4b\u304c\u767a\u9054\u3057\u3084\u3059\u304f\u3001\u77ed\u8ddd\u96e2\u8d70\u3084\u30a6\u30a8\u30a4\u30c8\u30ea\u30d5\u30c6\u30a3\u30f3\u30b0\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n\n\n\n<li><strong>RX\u578b<\/strong>\uff1a\u901f\u7b4b\u3068\u9045\u7b4b\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u53d6\u308c\u3066\u304a\u308a\u3001\u7dcf\u5408\u7684\u306a\u904b\u52d5\u80fd\u529b\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>XX\u578b<\/strong>\uff1a\u901f\u7b4b\u304c\u767a\u9054\u3057\u306b\u304f\u304f\u3001\u6301\u4e45\u529b\u304c\u6c42\u3081\u3089\u308c\u308b\u7af6\u6280\uff08\u30de\u30e9\u30bd\u30f3\u3084\u81ea\u8ee2\u8eca\u7af6\u6280\uff09\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2.2. ACE\u907a\u4f1d\u5b50\uff08\u8840\u5727\u8abf\u7bc0\u3068\u6301\u4e45\u529b\uff09<\/strong><\/h3>\n\n\n\n<p>ACE\uff08\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\uff09\u907a\u4f1d\u5b50\u306f\u3001\u8840\u6d41\u3084\u8840\u5727\u306e\u8abf\u6574\u306b\u95a2\u4e0e\u3057\u3001\u6301\u4e45\u529b\u3084\u5fc3\u80ba\u6a5f\u80fd\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>I\/I\u578b<\/strong>\uff1a\u6301\u4e45\u529b\u304c\u9ad8\u304f\u3001\u30de\u30e9\u30bd\u30f3\u3084\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u306a\u3069\u306e\u9577\u6642\u9593\u904b\u52d5\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n\n\n\n<li><strong>I\/D\u578b<\/strong>\uff1a\u6301\u4e45\u529b\u3068\u77ac\u767a\u529b\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u53d6\u308c\u3066\u304a\u308a\u3001\u591a\u304f\u306e\u30b9\u30dd\u30fc\u30c4\u3067\u9ad8\u3044\u9069\u5fdc\u80fd\u529b\u3092\u793a\u3059\u3002<\/li>\n\n\n\n<li><strong>D\/D\u578b<\/strong>\uff1a\u7b4b\u529b\u3084\u77ac\u767a\u529b\u304c\u5f37\u304f\u3001\u77ed\u8ddd\u96e2\u8d70\u3084\u30d1\u30ef\u30fc\u7cfb\u306e\u904b\u52d5\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2.3. PPARA\u907a\u4f1d\u5b50\uff08\u8102\u8cea\u4ee3\u8b1d\u3068\u6301\u4e45\u529b\uff09<\/strong><\/h3>\n\n\n\n<p>PPARA\uff08\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u5897\u6b96\u56e0\u5b50\u6d3b\u6027\u5316\u53d7\u5bb9\u4f53\u30a2\u30eb\u30d5\u30a1\uff09\u907a\u4f1d\u5b50\u306f\u3001\u8102\u8cea\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057\u3001\u6301\u4e45\u529b\u7cfb\u306e\u7af6\u6280\u3067\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>G\u578b<\/strong>\uff1a\u8102\u8cea\u4ee3\u8b1d\u304c\u6d3b\u767a\u3067\u3001\u9577\u6642\u9593\u306e\u6709\u9178\u7d20\u904b\u52d5\u306b\u9069\u5fdc\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>C\u578b<\/strong>\uff1a\u77ac\u767a\u7684\u306a\u30a8\u30cd\u30eb\u30ae\u30fc\u5229\u7528\u304c\u5f97\u610f\u3067\u3001\u30b9\u30d7\u30ea\u30f3\u30c8\u3084\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u5411\u3044\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u6700\u9069\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/27115557_m-1024x683.jpg\" alt=\"\u30d7\u30ed\u30c6\u30a4\u30f3\u3092\u98f2\u307f\u306a\u304c\u3089\u30c0\u30f3\u30d9\u30eb\u904b\u52d5\u3059\u308b\u7537\u6027\" class=\"wp-image-7415\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/27115557_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/27115557_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/27115557_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/27115557_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/27115557_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u3005\u306b\u9069\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u8a2d\u8a08\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3.1. \u901f\u7b4b\u578b\uff08ACTN3 RR\u578b\u30fbACE D\/D\u578b\uff09\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u7a2e\u76ee<\/strong>\uff1a\u30b9\u30d7\u30ea\u30f3\u30c8\u3001\u30a6\u30a8\u30a4\u30c8\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3001\u30b8\u30e3\u30f3\u30d7\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/li>\n\n\n\n<li><strong>\u63a8\u5968\u8ca0\u8377<\/strong>\uff1a\u9ad8\u8ca0\u8377\u30fb\u4f4e\u56de\u6570\uff0885\uff05\u4ee5\u4e0a\u306e1RM\u30673\uff5e6\u56de\uff09<\/li>\n\n\n\n<li><strong>\u4f11\u606f\u6642\u9593<\/strong>\uff1a\u77ed\u3081\uff0830\u79d2\uff5e1\u5206\uff09\u3067\u9ad8\u5f37\u5ea6\u3092\u7dad\u6301<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3.2. \u6301\u4e45\u529b\u578b\uff08ACTN3 XX\u578b\u30fbACE I\/I\u578b\uff09\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u7a2e\u76ee<\/strong>\uff1a\u30de\u30e9\u30bd\u30f3\u3001\u9577\u8ddd\u96e2\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u3001\u30c8\u30ec\u30a4\u30eb\u30e9\u30f3\u30cb\u30f3\u30b0<\/li>\n\n\n\n<li><strong>\u63a8\u5968\u8ca0\u8377<\/strong>\uff1a\u4e2d\uff5e\u4f4e\u5f37\u5ea6\u30fb\u9577\u6642\u9593\uff08\u5fc3\u62cd\u657060\uff5e70\uff05\u306e\u904b\u52d5\u30921\u6642\u9593\u4ee5\u4e0a\uff09<\/li>\n\n\n\n<li><strong>\u4f11\u606f\u6642\u9593<\/strong>\uff1a\u9577\u3081\uff081\uff5e2\u5206\uff09\u3067\u6301\u7d9a\u7684\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3.3. \u30d0\u30e9\u30f3\u30b9\u578b\uff08ACTN3 RX\u578b\u30fbACE I\/D\u578b\uff09\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6cd5<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u7a2e\u76ee<\/strong>\uff1a\u30b5\u30c3\u30ab\u30fc\u3001\u30d0\u30b9\u30b1\u30c3\u30c8\u30dc\u30fc\u30eb\u3001\u7dcf\u5408\u683c\u95d8\u6280<\/li>\n\n\n\n<li><strong>\u63a8\u5968\u8ca0\u8377<\/strong>\uff1a\u4e2d\u5f37\u5ea6\u30fb\u4e2d\u56de\u6570\uff0870\uff5e85\uff05\u306e1RM\u30678\uff5e12\u56de\uff09<\/li>\n\n\n\n<li><strong>\u4f11\u606f\u6642\u9593<\/strong>\uff1a\u4e2d\u7a0b\u5ea6\uff0845\u79d2\uff5e90\u79d2\uff09<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u907a\u4f1d\u5b50\u3068\u904b\u52d5\u56de\u5fa9\u529b\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u306e\u52b9\u679c\u3092\u6700\u5927\u5316\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u9069\u5207\u306a\u56de\u5fa9\u304c\u91cd\u8981\u3067\u3059\u3002\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u56de\u5fa9\u901f\u5ea6\u304c\u7570\u306a\u308b\u305f\u3081\u3001\u305d\u308c\u305e\u308c\u306b\u5408\u3063\u305f\u30ea\u30ab\u30d0\u30ea\u30fc\u65b9\u6cd5\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4.1. IL6\u907a\u4f1d\u5b50\uff08\u708e\u75c7\u3068\u56de\u5fa9\u901f\u5ea6\uff09<\/strong><\/h3>\n\n\n\n<p>IL6\uff08\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f36\uff09\u907a\u4f1d\u5b50\u306f\u3001\u7b4b\u8089\u306e\u708e\u75c7\u3084\u4fee\u5fa9\u306b\u95a2\u4e0e\u3059\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3092\u8abf\u7bc0\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>C\/C\u578b<\/strong>\uff1a\u708e\u75c7\u304c\u8d77\u3053\u308a\u3084\u3059\u304f\u3001\u56de\u5fa9\u306b\u6642\u9593\u304c\u304b\u304b\u308b \u2192 \u30b9\u30c8\u30ec\u30c3\u30c1\u3084\u30de\u30c3\u30b5\u30fc\u30b8\u3092\u7a4d\u6975\u7684\u306b\u53d6\u308a\u5165\u308c\u308b<\/li>\n\n\n\n<li><strong>C\/G\u578b<\/strong>\uff1a\u708e\u75c7\u304c\u9069\u5ea6\u306b\u6291\u3048\u3089\u308c\u3001\u56de\u5fa9\u304c\u6bd4\u8f03\u7684\u65e9\u3044 \u2192 \u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u983b\u5ea6\u3092\u5897\u3084\u305b\u308b<\/li>\n\n\n\n<li><strong>G\/G\u578b<\/strong>\uff1a\u708e\u75c7\u304c\u5c11\u306a\u304f\u3001\u56de\u5fa9\u304c\u65e9\u3044 \u2192 \u77ed\u671f\u9593\u3067\u306e\u9023\u7d9a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u53ef\u80fd<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4.2. CKM\u907a\u4f1d\u5b50\uff08\u7b4b\u8089\u4fee\u5fa9\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4f9b\u7d66\uff09<\/strong><\/h3>\n\n\n\n<p>CKM\uff08\u30af\u30ec\u30a2\u30c1\u30f3\u30ad\u30ca\u30fc\u30bcM\u578b\uff09\u907a\u4f1d\u5b50\u306f\u3001\u7b4b\u8089\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4f9b\u7d66\u3068\u4fee\u5fa9\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>A\u578b<\/strong>\uff1a\u7b4b\u640d\u50b7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u305f\u3081\u3001\u30af\u30ec\u30a2\u30c1\u30f3\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u6442\u53d6\u304c\u6709\u52b9<\/li>\n\n\n\n<li><strong>G\u578b<\/strong>\uff1a\u7b4b\u640d\u50b7\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u304f\u3001\u9ad8\u983b\u5ea6\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u9069\u5fdc\u3057\u3084\u3059\u3044<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u53c2\u8003\u6587\u732e\u30fb\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>ACTN3\u907a\u4f1d\u5b50\u3068\u904b\u52d5\u80fd\u529b<\/strong>\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">National Center for Biotechnology Information (NCBI)<\/a><\/li>\n\n\n\n<li><strong>ACE\u907a\u4f1d\u5b50\u3068\u6301\u4e45\u529b<\/strong>\uff1aJournal of Applied Physiology<\/li>\n\n\n\n<li><strong>IL6\u907a\u4f1d\u5b50\u3068\u7b4b\u8089\u56de\u5fa9<\/strong>\uff1a<a href=\"https:\/\/www.nature.com\/\">Nature Genetics<\/a><\/li>\n\n\n\n<li><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u3068\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9<\/strong>\uff1a<a href=\"https:\/\/link.springer.com\/\">Sports Medicine Journal<\/a><\/li>\n<\/ol>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u907a\u4f1d\u5b50\u3068\u904b\u52d5\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306e\u5411\u4e0a\u6226\u7565<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/3702341_m-1024x683.jpg\" alt=\"\" class=\"wp-image-6581\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3702341_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3702341_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3702341_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3702341_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3702341_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u81ea\u5206\u306e\u4f53\u8cea\u306b\u5408\u3063\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3092\u898b\u3064\u3051\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u98df\u4e8b\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3001\u7761\u7720\u306a\u3069\u306e\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3092\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>6.1. \u6804\u990a\u6442\u53d6\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u6804\u990a\u7d20\u306e\u5438\u53ce\u3084\u4ee3\u8b1d\u306f\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u3001\u904b\u52d5\u80fd\u529b\u306b\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u7279\u5b9a\u306e\u30d3\u30bf\u30df\u30f3\u3084\u30df\u30cd\u30e9\u30eb\u306e\u5fc5\u8981\u91cf\u304c\u5909\u308f\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FTO\u907a\u4f1d\u5b50<\/strong>\uff08\u80a5\u6e80\u95a2\u9023\uff09\uff1a\u70ad\u6c34\u5316\u7269\u306e\u4ee3\u8b1d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u7cd6\u8cea\u6442\u53d6\u91cf\u306e\u8abf\u6574\u304c\u5fc5\u8981\u3002<\/li>\n\n\n\n<li><strong>PPARGC1A\u907a\u4f1d\u5b50<\/strong>\uff08\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\uff09\uff1a\u8102\u8cea\u306e\u5229\u7528\u52b9\u7387\u304c\u7570\u306a\u308a\u3001\u6301\u4e45\u7cfb\u30b9\u30dd\u30fc\u30c4\u306e\u9069\u6027\u306b\u95a2\u4e0e\u3002<\/li>\n\n\n\n<li><strong>GC\u907a\u4f1d\u5b50<\/strong>\uff08\u30d3\u30bf\u30df\u30f3D\u53d7\u5bb9\u4f53\uff09\uff1a\u30d3\u30bf\u30df\u30f3D\u306e\u5438\u53ce\u52b9\u7387\u3092\u6c7a\u5b9a\u3057\u3001\u9aa8\u5bc6\u5ea6\u3084\u7b4b\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>6.2. \u907a\u4f1d\u5b50\u578b\u5225\u306e\u63a8\u5968\u6804\u990a\u7d20<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u77ac\u767a\u529b\u578b\uff08ACTN3 RR\u578b\u30fbACE D\/D\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5fc5\u8981\u306a\u6804\u990a\u7d20<\/strong>\uff1a\u30af\u30ec\u30a2\u30c1\u30f3\u3001BCAA\uff08\u5206\u5c90\u9396\u30a2\u30df\u30ce\u9178\uff09\u3001\u4e9c\u925b<\/li>\n\n\n\n<li><strong>\u98df\u4e8b\u306e\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a\u9ad8\u30bf\u30f3\u30d1\u30af\u98df\u3092\u5fc3\u304c\u3051\u3001\u7b4b\u5408\u6210\u3092\u6700\u5927\u5316\u3059\u308b<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u6301\u4e45\u529b\u578b\uff08ACTN3 XX\u578b\u30fbACE I\/I\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5fc5\u8981\u306a\u6804\u990a\u7d20<\/strong>\uff1a\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3001\u9244\u5206\u3001\u30d3\u30bf\u30df\u30f3B\u7fa4<\/li>\n\n\n\n<li><strong>\u98df\u4e8b\u306e\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a\u30a8\u30cd\u30eb\u30ae\u30fc\u6e90\u3068\u3057\u3066\u826f\u8cea\u306a\u8102\u8cea\u3092\u591a\u304f\u6442\u53d6\u3059\u308b<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30d0\u30e9\u30f3\u30b9\u578b\uff08ACTN3 RX\u578b\u30fbACE I\/D\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5fc5\u8981\u306a\u6804\u990a\u7d20<\/strong>\uff1a\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u3001\u6297\u9178\u5316\u7269\u8cea\uff08\u30d3\u30bf\u30df\u30f3C\u30fbE\uff09<\/li>\n\n\n\n<li><strong>\u98df\u4e8b\u306e\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a\u5168\u4f53\u306e\u6804\u990a\u30d0\u30e9\u30f3\u30b9\u3092\u8003\u3048\u3001\u70ad\u6c34\u5316\u7269\u30fb\u8102\u8cea\u30fb\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u9069\u91cf\u6442\u53d6\u3059\u308b<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u907a\u4f1d\u5b50\u3068\u75b2\u52b4\u56de\u5fa9\u306e\u6700\u9069\u5316<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u5f8c\u306e\u75b2\u52b4\u56de\u5fa9\u901f\u5ea6\u3082\u907a\u4f1d\u7684\u306b\u7570\u306a\u308a\u307e\u3059\u3002\u9069\u5207\u306a\u56de\u5fa9\u3092\u4fc3\u3059\u3053\u3068\u3067\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u52b9\u679c\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7.1. \u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u4ee3\u8b1d\u3068\u30b9\u30c8\u30ec\u30b9\u8010\u6027<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306f\u3001\u904e\u5270\u306b\u5206\u6ccc\u3055\u308c\u308b\u3068\u7b4b\u8089\u306e\u5206\u89e3\u3092\u4fc3\u3057\u3001\u56de\u5fa9\u3092\u9045\u3089\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NR3C1\u907a\u4f1d\u5b50<\/strong>\uff08\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\uff09\uff1a\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u611f\u53d7\u6027\u3092\u6c7a\u5b9a\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<\/li>\n\n\n\n<li><strong>FKBP5\u907a\u4f1d\u5b50<\/strong>\uff08\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u8abf\u7bc0\uff09\uff1a\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u8abf\u6574\u304c\u3046\u307e\u304f\u3044\u304b\u306a\u3044\u3068\u3001\u75b2\u52b4\u304c\u9577\u5f15\u304f\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7.2. \u907a\u4f1d\u5b50\u578b\u5225\u306e\u56de\u5fa9\u6226\u7565<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u611f\u53d7\u6027\u304c\u9ad8\u3044\uff08NR3C1\u5909\u7570\u3042\u308a\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u63a8\u5968\u56de\u5fa9\u6cd5<\/strong>\uff1a\u7791\u60f3\u3001\u30e8\u30ac\u3001\u8efd\u3044\u30b9\u30c8\u30ec\u30c3\u30c1<\/li>\n\n\n\n<li><strong>\u98df\u4e8b\u306e\u5de5\u592b<\/strong>\uff1a\u6297\u708e\u75c7\u4f5c\u7528\u306e\u3042\u308b\u98df\u54c1\uff08\u30bf\u30fc\u30e1\u30ea\u30c3\u30af\u3001\u30b7\u30e7\u30a6\u30ac\uff09\u3092\u6442\u53d6<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7b4b\u640d\u50b7\u30ea\u30b9\u30af\u304c\u9ad8\u3044\uff08IL6 C\/C\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u63a8\u5968\u56de\u5fa9\u6cd5<\/strong>\uff1aEAA\uff08\u5fc5\u9808\u30a2\u30df\u30ce\u9178\uff09\u3084\u30d7\u30ed\u30c6\u30a4\u30f3\u306e\u6442\u53d6<\/li>\n\n\n\n<li><strong>\u98df\u4e8b\u306e\u5de5\u592b<\/strong>\uff1a\u6297\u9178\u5316\u98df\u54c1\uff08\u30d6\u30eb\u30fc\u30d9\u30ea\u30fc\u3001\u30c0\u30fc\u30af\u30c1\u30e7\u30b3\u30ec\u30fc\u30c8\uff09\u3092\u591a\u304f\u6442\u308b<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u56de\u5fa9\u529b\u304c\u9ad8\u3044\uff08G\/G\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u63a8\u5968\u56de\u5fa9\u6cd5<\/strong>\uff1a\u7a4d\u6975\u7684\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u7d99\u7d9a\u304c\u53ef\u80fd<\/li>\n\n\n\n<li><strong>\u98df\u4e8b\u306e\u5de5\u592b<\/strong>\uff1a\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u70ad\u6c34\u5316\u7269\u3092\u30d0\u30e9\u30f3\u30b9\u3088\u304f\u6442\u53d6<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u907a\u4f1d\u5b50\u3068\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/30527646_m-1024x683.jpg\" alt=\"\u30b5\u30f3\u30c9\u30d0\u30c3\u30b0\u306b\u30d1\u30f3\u30c1\u3092\u3059\u308b\u8d64\u8272\u306e\u30a6\u30a7\u30a2\u306e\u7537\u6027\" class=\"wp-image-8190\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30527646_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30527646_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30527646_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30527646_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30527646_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306f\u904b\u52d5\u306e\u7d99\u7d9a\u529b\u3084\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u306b\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>8.1. \u30c9\u30fc\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53\u3068\u904b\u52d5\u7fd2\u6163<\/strong><\/h3>\n\n\n\n<p>\u30c9\u30fc\u30d1\u30df\u30f3\u306f\u300c\u3084\u308b\u6c17\u300d\u306b\u95a2\u308f\u308b\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3067\u3042\u308a\u3001\u4ee5\u4e0b\u306e\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>DRD2\u907a\u4f1d\u5b50<\/strong>\uff08\u30c9\u30fc\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53\uff09\uff1a\u904b\u52d5\u306b\u3088\u308b\u5feb\u611f\u306e\u611f\u3058\u3084\u3059\u3055\u3092\u6c7a\u5b9a\u3002<\/li>\n\n\n\n<li><strong>BDNF\u907a\u4f1d\u5b50<\/strong>\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09\uff1a\u904b\u52d5\u306b\u3088\u308b\u30b9\u30c8\u30ec\u30b9\u8efd\u6e1b\u52b9\u679c\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>8.2. \u907a\u4f1d\u5b50\u578b\u5225\u306e\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u7dad\u6301\u6cd5<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u904b\u52d5\u306e\u5feb\u611f\u3092\u611f\u3058\u306b\u304f\u3044\uff08DRD2\u5909\u7570\u3042\u308a\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5bfe\u7b56<\/strong>\uff1a\u5831\u916c\u578b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08\u76ee\u6a19\u9054\u6210\u3054\u3068\u306b\u3054\u8912\u7f8e\u3092\u8a2d\u5b9a\uff09\u3092\u5c0e\u5165<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u904b\u52d5\u30b9\u30c8\u30ec\u30b9\u3092\u611f\u3058\u3084\u3059\u3044\uff08BDNF Val\/Met\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5bfe\u7b56<\/strong>\uff1a\u77ed\u6642\u9593\u306e\u904b\u52d5\u3092\u8907\u6570\u56de\u306b\u5206\u3051\u3066\u884c\u3046\uff08\u4f8b\uff1a15\u5206\u00d72\u56de\uff09<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u304c\u6301\u7d9a\u3057\u306b\u304f\u3044\uff08COMT Met\/Met\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5bfe\u7b56<\/strong>\uff1a\u30c1\u30fc\u30e0\u30b9\u30dd\u30fc\u30c4\u3084\u30b0\u30eb\u30fc\u30d7\u30ef\u30fc\u30af\u30a2\u30a6\u30c8\u3092\u53d6\u308a\u5165\u308c\u308b<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u30b9\u30dd\u30fc\u30c4\u9078\u624b\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u7ba1\u7406<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/4192159_m-1024x683.jpg\" alt=\"\u30b5\u30c3\u30ab\u30fc\u3000\u30d5\u30c3\u30c8\u30dc\u30fc\u30eb\" class=\"wp-image-5521\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4192159_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4192159_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4192159_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4192159_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4192159_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30c8\u30c3\u30d7\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3057\u3001\u81ea\u5206\u306e\u7279\u6027\u306b\u5408\u3063\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u56de\u5fa9\u6226\u7565\u3092\u63a1\u7528\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>9.1. \u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3092\u6d3b\u7528\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30ed\u30b0\u30e9\u30e0<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30dd\u30fc\u30c4\u30c1\u30fc\u30e0\u3084\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65bd\u8a2d\u3067\u306f\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u30c7\u30fc\u30bf\u3092\u3082\u3068\u306b\u500b\u5225\u306e\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u4f5c\u6210\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7b4b\u8089\u7279\u6027\uff08ACTN3\u30fbACE\uff09<\/strong> \u2192 \u9069\u5207\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f37\u5ea6\u306e\u8a2d\u5b9a<\/li>\n\n\n\n<li><strong>\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\uff08PPARA\uff09<\/strong> \u2192 \u98df\u4e8b\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u6700\u9069\u5316<\/li>\n\n\n\n<li><strong>\u56de\u5fa9\u80fd\u529b\uff08IL6\u30fbNR3C1\uff09<\/strong> \u2192 \u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e\u30b1\u30a2\u65b9\u6cd5\u306e\u9078\u5b9a<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>9.2. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d3b\u7528\u4e8b\u4f8b<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9678\u4e0a\u7af6\u6280<\/strong>\uff1a100m\u9078\u624b\u304cACTN3 RR\u578b\u3067\u3042\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u3001\u30b9\u30d7\u30ea\u30f3\u30c8\u7279\u5316\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u5b9f\u65bd\u3002<\/li>\n\n\n\n<li><strong>\u30de\u30e9\u30bd\u30f3<\/strong>\uff1aACE I\/I\u578b\u306e\u9078\u624b\u304c\u6301\u4e45\u7cfb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u5f37\u5316\u3057\u3001\u6301\u4e45\u529b\u3092\u6700\u5927\u9650\u306b\u767a\u63ee\u3002<\/li>\n\n\n\n<li><strong>\u30b5\u30c3\u30ab\u30fc<\/strong>\uff1aACTN3 RX\u578b\u306e\u9078\u624b\u304c\u77ac\u767a\u529b\u3068\u6301\u4e45\u529b\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u53d6\u308b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u63a1\u7528\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>10. \u907a\u4f1d\u5b50\u3068\u30b9\u30dd\u30fc\u30c4\u969c\u5bb3\u30ea\u30b9\u30af\u306e\u95a2\u4fc2<\/strong><\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30b9\u30dd\u30fc\u30c4\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u3092\u4e8b\u524d\u306b\u628a\u63e1\u3057\u3001\u9069\u5207\u306a\u5bfe\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u7b4b\u8089\u3084\u8171\u3001\u9aa8\u306e\u5f37\u5ea6\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u305f\u3081\u3001\u500b\u3005\u306e\u7279\u6027\u306b\u5fdc\u3058\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u4e88\u9632\u7b56\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>10.1. \u9aa8\u5bc6\u5ea6\u3068\u9aa8\u6298\u30ea\u30b9\u30af\u3092\u6c7a\u5b9a\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>COL1A1\u907a\u4f1d\u5b50<\/strong>\uff08\u30b3\u30e9\u30fc\u30b2\u30f3\u751f\u6210\uff09\uff1a\u9aa8\u306e\u5f37\u5ea6\u3084\u5f3e\u529b\u6027\u306b\u95a2\u4e0e\u3057\u3001\u9aa8\u6298\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002\n<ul class=\"wp-block-list\">\n<li><strong>TT\u578b<\/strong>\uff1a\u9aa8\u5bc6\u5ea6\u304c\u4f4e\u304f\u3001\u9aa8\u6298\u3057\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>GG\u578b<\/strong>\uff1a\u9aa8\u304c\u5f37\u304f\u3001\u885d\u6483\u306b\u8010\u3048\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>VDR\u907a\u4f1d\u5b50<\/strong>\uff08\u30d3\u30bf\u30df\u30f3D\u53d7\u5bb9\u4f53\uff09\uff1a\u30ab\u30eb\u30b7\u30a6\u30e0\u306e\u5438\u53ce\u7387\u3092\u6c7a\u5b9a\u3057\u3001\u9aa8\u306e\u6210\u9577\u3084\u4fee\u5fa9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>10.2. \u976d\u5e2f\u640d\u50b7\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>COL5A1\u907a\u4f1d\u5b50<\/strong>\uff08\u30b3\u30e9\u30fc\u30b2\u30f3\u5408\u6210\uff09\uff1a\u976d\u5e2f\u306e\u67d4\u8edf\u6027\u306b\u5f71\u97ff\u3057\u3001\u524d\u5341\u5b57\u976d\u5e2f\uff08ACL\uff09\u640d\u50b7\u306e\u30ea\u30b9\u30af\u3092\u6c7a\u5b9a\u3059\u308b\u3002\n<ul class=\"wp-block-list\">\n<li><strong>TT\u578b<\/strong>\uff1a\u976d\u5e2f\u304c\u786c\u304f\u3001\u640d\u50b7\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>CC\u578b<\/strong>\uff1a\u976d\u5e2f\u304c\u67d4\u8edf\u3067\u3001\u602a\u6211\u3092\u3057\u306b\u304f\u3044\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>10.3. \u7b4b\u640d\u50b7\u30ea\u30b9\u30af\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CKM\u907a\u4f1d\u5b50<\/strong>\uff08\u30af\u30ec\u30a2\u30c1\u30f3\u30ad\u30ca\u30fc\u30bc\uff09\uff1a\u7b4b\u8089\u306e\u640d\u50b7\u30ea\u30b9\u30af\u3092\u6c7a\u5b9a\u3057\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e\u56de\u5fa9\u901f\u5ea6\u306b\u5f71\u97ff\u3059\u308b\u3002\n<ul class=\"wp-block-list\">\n<li><strong>A\u578b<\/strong>\uff1a\u7b4b\u640d\u50b7\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u3001\u56de\u5fa9\u306b\u6642\u9593\u304c\u304b\u304b\u308b\u3002<\/li>\n\n\n\n<li><strong>G\u578b<\/strong>\uff1a\u7b4b\u640d\u50b7\u306e\u30ea\u30b9\u30af\u304c\u4f4e\u304f\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e\u56de\u5fa9\u304c\u65e9\u3044\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. \u907a\u4f1d\u5b50\u3068\u795e\u7d4c\u7cfb\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/22280908_m-1024x768.jpg\" alt=\"\" class=\"wp-image-8512\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/22280908_m-1024x768.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/22280908_m-300x225.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/22280908_m-768x576.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/22280908_m-1536x1152.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/22280908_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u904b\u52d5\u80fd\u529b\u306f\u7b4b\u8089\u306e\u7279\u6027\u3060\u3051\u3067\u306a\u304f\u3001\u795e\u7d4c\u7cfb\u306e\u50cd\u304d\u306b\u3082\u5927\u304d\u304f\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u3001\u53cd\u5fdc\u901f\u5ea6\u3084\u52d5\u4f5c\u306e\u6b63\u78ba\u6027\u304c\u7570\u306a\u308a\u3001\u7279\u5b9a\u306e\u30b9\u30dd\u30fc\u30c4\u306b\u5411\u3044\u305f\u795e\u7d4c\u7279\u6027\u3092\u6301\u3064\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>11.1. \u904b\u52d5\u795e\u7d4c\u3068\u53cd\u5c04\u901f\u5ea6\u3092\u6c7a\u5b9a\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>BDNF\u907a\u4f1d\u5b50<\/strong>\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09\uff1a\u795e\u7d4c\u7d30\u80de\u306e\u6210\u9577\u3068\u53ef\u5851\u6027\u3092\u5236\u5fa1\u3057\u3001\u904b\u52d5\u5b66\u7fd2\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002\n<ul class=\"wp-block-list\">\n<li><strong>Val\/Val\u578b<\/strong>\uff1a\u795e\u7d4c\u306e\u4f1d\u9054\u901f\u5ea6\u304c\u901f\u304f\u3001\u65b0\u3057\u3044\u904b\u52d5\u30b9\u30ad\u30eb\u3092\u7fd2\u5f97\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>Val\/Met\u578b<\/strong>\uff1a\u5b66\u7fd2\u901f\u5ea6\u306f\u3084\u3084\u9045\u3044\u304c\u3001\u4e00\u5ea6\u7fd2\u5f97\u3057\u305f\u52d5\u4f5c\u3092\u9577\u671f\u9593\u7dad\u6301\u3067\u304d\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>SLC6A4\u907a\u4f1d\u5b50<\/strong>\uff08\u30bb\u30ed\u30c8\u30cb\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\uff09\uff1a\u96c6\u4e2d\u529b\u3084\u30d7\u30ec\u30c3\u30b7\u30e3\u30fc\u8010\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>11.2. \u53cd\u5fdc\u901f\u5ea6\u3068\u8996\u899a\u51e6\u7406\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CHRNA4\u907a\u4f1d\u5b50<\/strong>\uff08\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u53d7\u5bb9\u4f53\uff09\uff1a\u6ce8\u610f\u529b\u3068\u96c6\u4e2d\u529b\u3092\u6c7a\u5b9a\u3057\u3001\u30b9\u30dd\u30fc\u30c4\u4e2d\u306e\u610f\u601d\u6c7a\u5b9a\u901f\u5ea6\u306b\u5f71\u97ff\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>ADRA2A\u907a\u4f1d\u5b50<\/strong>\uff08\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d7\u5bb9\u4f53\uff09\uff1a\u30b9\u30c8\u30ec\u30b9\u74b0\u5883\u4e0b\u3067\u306e\u5224\u65ad\u529b\u3084\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u7dad\u6301\u306b\u95a2\u4e0e\u3059\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>12. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u5411\u4e0a\u306e\u5b9f\u8df5\u4f8b<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3066\u3001\u30a2\u30b9\u30ea\u30fc\u30c8\u3084\u30d5\u30a3\u30c3\u30c8\u30cd\u30b9\u611b\u597d\u5bb6\u304c\u3069\u306e\u3088\u3046\u306b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u98df\u4e8b\u3001\u56de\u5fa9\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u6700\u9069\u5316\u3067\u304d\u308b\u304b\u3092\u5177\u4f53\u7684\u306b\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>12.1. \u907a\u4f1d\u5b50\u578b\u5225\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30ed\u30b0\u30e9\u30e0<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30b9\u30d7\u30ea\u30f3\u30bf\u30fc\uff08ACTN3 RR\u578b\u30fbACE D\/D\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong>\uff1a\u77ed\u8ddd\u96e2\u30c0\u30c3\u30b7\u30e5\u3001\u30aa\u30ea\u30f3\u30d4\u30c3\u30af\u30ea\u30d5\u30c6\u30a3\u30f3\u30b0\u3001\u30d7\u30e9\u30a4\u30aa\u30e1\u30c8\u30ea\u30af\u30b9<\/li>\n\n\n\n<li><strong>\u6804\u990a\u6226\u7565<\/strong>\uff1a\u9ad8\u30bf\u30f3\u30d1\u30af\u98df\uff0b\u30af\u30ec\u30a2\u30c1\u30f3\u88dc\u7d66<\/li>\n\n\n\n<li><strong>\u56de\u5fa9\u65b9\u6cd5<\/strong>\uff1a\u4f4e\u6e29\u7642\u6cd5\uff08\u30a2\u30a4\u30b9\u30d0\u30b9\uff09\u3084\u30de\u30c3\u30b5\u30fc\u30b8\u3092\u91cd\u8996<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u6301\u4e45\u529b\u30a2\u30b9\u30ea\u30fc\u30c8\uff08ACTN3 XX\u578b\u30fbACE I\/I\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong>\uff1a\u9577\u8ddd\u96e2\u8d70\u3001\u5fc3\u80ba\u6a5f\u80fd\u5411\u4e0a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3001\u30a4\u30f3\u30bf\u30fc\u30d0\u30eb\u8d70<\/li>\n\n\n\n<li><strong>\u6804\u990a\u6226\u7565<\/strong>\uff1a\u9ad8\u70ad\u6c34\u5316\u7269\uff0b\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3092\u8c4a\u5bcc\u306b\u6442\u53d6<\/li>\n\n\n\n<li><strong>\u56de\u5fa9\u65b9\u6cd5<\/strong>\uff1a\u30a2\u30af\u30c6\u30a3\u30d6\u30ea\u30ab\u30d0\u30ea\u30fc\uff08\u8efd\u3044\u30b8\u30e7\u30ae\u30f3\u30b0\u3084\u30e8\u30ac\uff09<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u683c\u95d8\u6280\u9078\u624b\uff08ACTN3 RX\u578b\u30fbACE I\/D\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong>\uff1a\u7b4b\u529b\uff0b\u6301\u4e45\u529b\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u53d6\u308b\u7dcf\u5408\u7684\u30d7\u30ed\u30b0\u30e9\u30e0<\/li>\n\n\n\n<li><strong>\u6804\u990a\u6226\u7565<\/strong>\uff1a\u30bf\u30f3\u30d1\u30af\u8cea\u30fb\u8102\u8cea\u30fb\u70ad\u6c34\u5316\u7269\u3092\u30d0\u30e9\u30f3\u30b9\u3088\u304f\u6442\u53d6<\/li>\n\n\n\n<li><strong>\u56de\u5fa9\u65b9\u6cd5<\/strong>\uff1a\u52d5\u7684\u30b9\u30c8\u30ec\u30c3\u30c1\u3084PNF\u30b9\u30c8\u30ec\u30c3\u30c1\u3092\u6d3b\u7528<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>13. \u907a\u4f1d\u5b50\u3068\u7761\u7720\u306e\u95a2\u4fc2\uff08\u904b\u52d5\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3078\u306e\u5f71\u97ff\uff09<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/31566268_m-1024x683.jpg\" alt=\"\u671d\u306b\u30d9\u30c3\u30c9\u3067\u8d77\u5e8a\u3059\u308b\u82e5\u3044\u30a2\u30b8\u30a2\u4eba\u306e\u5973\u6027\" class=\"wp-image-8174\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31566268_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31566268_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31566268_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31566268_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31566268_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u7761\u7720\u306f\u904b\u52d5\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306e\u5411\u4e0a\u3068\u56de\u5fa9\u306b\u6b20\u304b\u305b\u307e\u305b\u3093\u3002\u907a\u4f1d\u7684\u306a\u9055\u3044\u306b\u3088\u3063\u3066\u3001\u7761\u7720\u306e\u8cea\u3084\u5fc5\u8981\u306a\u7761\u7720\u6642\u9593\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>13.1. \u7761\u7720\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CLOCK\u907a\u4f1d\u5b50<\/strong>\uff08\u6982\u65e5\u30ea\u30ba\u30e0\u306e\u8abf\u7bc0\uff09\uff1a\u7761\u7720\u306e\u8cea\u3084\u591c\u578b\u30fb\u671d\u578b\u306e\u50be\u5411\u3092\u6c7a\u5b9a\u3002<\/li>\n\n\n\n<li><strong>PER3\u907a\u4f1d\u5b50<\/strong>\uff08\u7761\u7720\u6642\u9593\u306e\u9577\u77ed\uff09\uff1a\u30b7\u30e7\u30fc\u30c8\u30b9\u30ea\u30fc\u30d1\u30fc\u304b\u30ed\u30f3\u30b0\u30b9\u30ea\u30fc\u30d1\u30fc\u304b\u3092\u6c7a\u5b9a\u3002<\/li>\n\n\n\n<li><strong>ADRB1\u907a\u4f1d\u5b50<\/strong>\uff08\u899a\u9192\u3068\u7761\u7720\u306e\u5207\u308a\u66ff\u3048\uff09\uff1a\u6df1\u3044\u7761\u7720\u306e\u8cea\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>13.2. \u907a\u4f1d\u5b50\u578b\u5225\u306e\u7761\u7720\u6539\u5584\u6226\u7565<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u77ed\u6642\u9593\u7761\u7720\u3067\u3082\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u7dad\u6301\u3057\u3084\u3059\u3044\uff08PER3\u77ed\u7e2e\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u663c\u5bdd\uff08\u30d1\u30ef\u30fc\u30ca\u30c3\u30d7\uff09\u3092\u6d3b\u7528\u3057\u3001\u7761\u7720\u4e0d\u8db3\u3092\u88dc\u3046<\/li>\n\n\n\n<li>\u5c31\u5bdd\u524d\u306e\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3092\u907f\u3051\u3001\u6df1\u3044\u7761\u7720\u3092\u78ba\u4fdd<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u9577\u6642\u9593\u7761\u7720\u304c\u5fc5\u8981\uff08PER3\u9577\u578b\uff09<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>8\u6642\u9593\u4ee5\u4e0a\u306e\u7761\u7720\u3092\u78ba\u4fdd\u3057\u3001\u5c31\u5bdd\u6642\u9593\u3092\u56fa\u5b9a\u3059\u308b<\/li>\n\n\n\n<li>\u5915\u65b9\u4ee5\u964d\u306e\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6\u3092\u63a7\u3048\u308b<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>14. \u53c2\u8003\u6587\u732e\u30fb\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>ACTN3\u907a\u4f1d\u5b50\u3068\u904b\u52d5\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9<\/strong>\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">National Center for Biotechnology Information (NCBI)<\/a><\/li>\n\n\n\n<li><strong>ACE\u907a\u4f1d\u5b50\u3068\u6301\u4e45\u529b<\/strong>\uff1aJournal of Applied Physiology<\/li>\n\n\n\n<li><strong>COL1A1\u907a\u4f1d\u5b50\u3068\u9aa8\u6298\u30ea\u30b9\u30af<\/strong>\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">Bone Journal<\/a><\/li>\n\n\n\n<li><strong>BDNF\u907a\u4f1d\u5b50\u3068\u904b\u52d5\u5b66\u7fd2<\/strong>\uff1a<a href=\"https:\/\/www.nature.com\/\">Nature Neuroscience<\/a><\/li>\n\n\n\n<li><strong>CLOCK\u907a\u4f1d\u5b50\u3068\u7761\u7720\u306e\u95a2\u4fc2<\/strong>\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">Sleep Medicine Reviews<\/a><\/li>\n<\/ol>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>15. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u672a\u6765<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/29770529_m-1024x585.jpg\" alt=\"\u8996\u899a\u7684\u8868\u73fe\u3067\u4e8b\u696d\u306e\u6210\u9577\u3092\u5206\u6790\u3059\u308b\" class=\"wp-image-8413\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29770529_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29770529_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29770529_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29770529_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29770529_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u500b\u3005\u306e\u4f53\u8cea\u306b\u5408\u308f\u305b\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u30b9\u30dd\u30fc\u30c4\u6226\u7565\u304c\u6025\u901f\u306b\u767a\u5c55\u3057\u3066\u3044\u307e\u3059\u3002\u30b9\u30dd\u30fc\u30c4\u79d1\u5b66\u3068\u907a\u4f1d\u5b66\u306e\u878d\u5408\u306b\u3088\u3063\u3066\u3001\u4eca\u5f8c\u3069\u306e\u3088\u3046\u306a\u5909\u5316\u304c\u8d77\u3053\u308b\u306e\u304b\u3092\u63a2\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>15.1. AI\u3068\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306b\u3088\u308b\u500b\u5225\u5316\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/h3>\n\n\n\n<p>\u8fd1\u5e74\u3001\u4eba\u5de5\u77e5\u80fd\uff08AI\uff09\u3092\u6d3b\u7528\u3057\u305f\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u89e3\u6790\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002AI\u306f\u81a8\u5927\u306a\u907a\u4f1d\u60c5\u5831\u3068\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30c7\u30fc\u30bf\u3092\u89e3\u6790\u3057\u3001\u500b\u4eba\u3054\u3068\u306b\u6700\u9069\u306a\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u81ea\u52d5\u3067\u4f5c\u6210\u3059\u308b\u6280\u8853\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u907a\u4f1d\u5b50\u00d7AI\u306e\u6d3b\u7528\u4f8b<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u907a\u4f1d\u5b50\u578b\u306b\u57fa\u3065\u304f\u6700\u9069\u306a\u904b\u52d5\u5f37\u5ea6\u3084\u983b\u5ea6\u306e\u63d0\u6848<\/li>\n\n\n\n<li>\u602a\u6211\u306e\u30ea\u30b9\u30af\u3092\u4e88\u6e2c\u3057\u3001\u56de\u907f\u3059\u308b\u305f\u3081\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u8a08\u753b\u306e\u4f5c\u6210<\/li>\n\n\n\n<li>\u7761\u7720\u30fb\u6804\u990a\u30fb\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306e\u7d71\u5408\u7ba1\u7406\u306b\u3088\u308b\u7dcf\u5408\u7684\u306a\u30a2\u30b9\u30ea\u30fc\u30c8\u30b1\u30a2<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u6280\u8853\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u500b\u4eba\u306e\u4f53\u8cea\u306b\u5fdc\u3058\u305f\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u53ef\u80fd\u306b\u306a\u308a\u3001\u52b9\u679c\u7684\u304b\u3064\u5b89\u5168\u306a\u904b\u52d5\u304c\u5b9f\u73fe\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>15.2. \u907a\u4f1d\u5b50\u7de8\u96c6\u3068\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306e\u5411\u4e0a<\/strong><\/h3>\n\n\n\n<p>CRISPR-Cas9\u6280\u8853\u306a\u3069\u306e\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u5c06\u6765\u7684\u306b\u306f\u907a\u4f1d\u5b50\u30ec\u30d9\u30eb\u3067\u904b\u52d5\u80fd\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u907a\u4f1d\u5b50\u7de8\u96c6\u306b\u3088\u308b\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u5411\u4e0a\u306e\u53ef\u80fd\u6027<\/strong>\n<ul class=\"wp-block-list\">\n<li>ACTN3\u907a\u4f1d\u5b50\u306e\u6539\u5909\u306b\u3088\u308b\u77ac\u767a\u529b\u306e\u5411\u4e0a<\/li>\n\n\n\n<li>ACE\u907a\u4f1d\u5b50\u306e\u7de8\u96c6\u306b\u3088\u308b\u6301\u4e45\u529b\u306e\u5411\u4e0a<\/li>\n\n\n\n<li>BDNF\u907a\u4f1d\u5b50\u306e\u8abf\u6574\u306b\u3088\u308b\u795e\u7d4c\u53ef\u5851\u6027\u306e\u5f37\u5316<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u30b9\u30dd\u30fc\u30c4\u7af6\u6280\u306b\u304a\u3044\u3066\u907a\u4f1d\u5b50\u7de8\u96c6\u304c\u8a31\u5bb9\u3055\u308c\u308b\u304b\u3069\u3046\u304b\u306f\u502b\u7406\u7684\u306a\u554f\u984c\u3092\u542b\u3093\u3067\u304a\u308a\u3001\u56fd\u969b\u30aa\u30ea\u30f3\u30d4\u30c3\u30af\u59d4\u54e1\u4f1a\uff08IOC\uff09\u3084\u4e16\u754c\u30a2\u30f3\u30c1\u30fb\u30c9\u30fc\u30d4\u30f3\u30b0\u6a5f\u95a2\uff08WADA\uff09\u306b\u3088\u308b\u898f\u5236\u304c\u5fc5\u8981\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>16. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u5fc3\u7406\u7684\u8981\u56e0\u306e\u95a2\u9023\u6027<\/strong><\/h2>\n\n\n\n<p>\u904b\u52d5\u80fd\u529b\u3060\u3051\u3067\u306a\u304f\u3001\u30b9\u30dd\u30fc\u30c4\u306b\u304a\u3051\u308b\u30e1\u30f3\u30bf\u30eb\u9762\u3082\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u3001\u7af6\u6280\u4e2d\u306e\u96c6\u4e2d\u529b\u3084\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3001\u52dd\u8ca0\u5f37\u3055\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>16.1. \u904b\u52d5\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u30e1\u30f3\u30bf\u30eb\u95a2\u9023\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>COMT\u907a\u4f1d\u5b50\uff08\u30ab\u30c6\u30b3\u30fc\u30eb-O-\u30e1\u30c1\u30eb\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc\uff09<\/strong>\n<ul class=\"wp-block-list\">\n<li><strong>Val\/Val\u578b<\/strong>\uff1a\u30d7\u30ec\u30c3\u30b7\u30e3\u30fc\u306b\u5f37\u304f\u3001\u51b7\u9759\u306a\u5224\u65ad\u304c\u5f97\u610f<\/li>\n\n\n\n<li><strong>Met\/Met\u578b<\/strong>\uff1a\u30b9\u30c8\u30ec\u30b9\u306b\u654f\u611f\u3060\u304c\u3001\u96c6\u4e2d\u529b\u304c\u9ad8\u3044<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>DRD4\u907a\u4f1d\u5b50\uff08\u30c9\u30fc\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53\uff09<\/strong>\n<ul class=\"wp-block-list\">\n<li><strong>7R\u30a2\u30ec\u30eb\u578b<\/strong>\uff1a\u30ea\u30b9\u30af\u3092\u597d\u3080\u6027\u683c\u3067\u3001\u30a2\u30b0\u30ec\u30c3\u30b7\u30d6\u306a\u30d7\u30ec\u30fc\u30b9\u30bf\u30a4\u30eb\u306b\u5411\u3044\u3066\u3044\u308b<\/li>\n\n\n\n<li><strong>\u975e7R\u578b<\/strong>\uff1a\u5b89\u5b9a\u5fd7\u5411\u3067\u3001\u614e\u91cd\u306a\u6226\u7565\u3092\u597d\u3080<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>OXTR\u907a\u4f1d\u5b50\uff08\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u53d7\u5bb9\u4f53\uff09<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u30c1\u30fc\u30e0\u30b9\u30dd\u30fc\u30c4\u3078\u306e\u9069\u6027\u3092\u6c7a\u5b9a\u3057\u3001\u5354\u8abf\u6027\u3084\u4fe1\u983c\u611f\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>16.2. \u907a\u4f1d\u5b50\u306b\u57fa\u3065\u3044\u305f\u30e1\u30f3\u30bf\u30eb\u5f37\u5316\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u578b\u306b\u3088\u3063\u3066\u3001\u30e1\u30f3\u30bf\u30eb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u52b9\u679c\u304c\u7570\u306a\u308b\u305f\u3081\u3001\u500b\u5225\u306b\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d7\u30ec\u30c3\u30b7\u30e3\u30fc\u306b\u5f31\u3044\u30bf\u30a4\u30d7\uff08COMT Met\/Met\u578b\uff09<\/strong> \u2192 \u8a8d\u77e5\u884c\u52d5\u7642\u6cd5\uff08CBT\uff09\u3092\u53d6\u308a\u5165\u308c\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3092\u5f37\u5316<\/li>\n\n\n\n<li><strong>\u96c6\u4e2d\u529b\u304c\u4f4e\u4e0b\u3057\u3084\u3059\u3044\u30bf\u30a4\u30d7\uff08DRD4 7R\u578b\uff09<\/strong> \u2192 \u7791\u60f3\u3084\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u3092\u6d3b\u7528\u3057\u3001\u6301\u7d9a\u7684\u306a\u96c6\u4e2d\u529b\u3092\u935b\u3048\u308b<\/li>\n\n\n\n<li><strong>\u30c1\u30fc\u30e0\u30b9\u30dd\u30fc\u30c4\u5411\u304d\u306e\u30bf\u30a4\u30d7\uff08OXTR\u5909\u7570\u3042\u308a\uff09<\/strong> \u2192 \u30bd\u30fc\u30b7\u30e3\u30eb\u30b5\u30dd\u30fc\u30c8\u3092\u6d3b\u7528\u3057\u3001\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u3092\u9ad8\u3081\u308b<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>17. \u907a\u4f1d\u5b50\u60c5\u5831\u3068\u7af6\u6280\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306e\u6700\u9069\u5316<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"946\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/1017471_m-1024x946.jpg\" alt=\"\" class=\"wp-image-5551\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/1017471_m-1024x946.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/1017471_m-300x277.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/1017471_m-768x710.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/1017471_m-1536x1419.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/1017471_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u7af6\u6280\u4e2d\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u3084\u75b2\u52b4\u7ba1\u7406\u3001\u8a66\u5408\u524d\u306e\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30cb\u30f3\u30b0\u306a\u3069\u3092\u3088\u308a\u7cbe\u5bc6\u306b\u7ba1\u7406\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>17.1. \u8a66\u5408\u524d\u306e\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30cb\u30f3\u30b0\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PPARGC1A\u907a\u4f1d\u5b50\uff08\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\uff09<\/strong> \u2192 \u6301\u4e45\u7cfb\u30b9\u30dd\u30fc\u30c4\u306e\u9078\u624b\u306f\u8a66\u5408\u524d\u306e\u30b0\u30ea\u30b3\u30fc\u30b2\u30f3\u30ed\u30fc\u30c7\u30a3\u30f3\u30b0\u304c\u6709\u52b9<\/li>\n\n\n\n<li><strong>CYP1A2\u907a\u4f1d\u5b50\uff08\u30ab\u30d5\u30a7\u30a4\u30f3\u4ee3\u8b1d\uff09<\/strong> \u2192 \u30ab\u30d5\u30a7\u30a4\u30f3\u306e\u52b9\u679c\u304c\u9ad8\u3044\u9078\u624b\u306f\u8a66\u5408\u524d\u306e\u30b3\u30fc\u30d2\u30fc\u6442\u53d6\u3067\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u5411\u4e0a<\/li>\n\n\n\n<li><strong>BDNF\u907a\u4f1d\u5b50\uff08\u795e\u7d4c\u53ef\u5851\u6027\uff09<\/strong> \u2192 \u77ed\u671f\u8a18\u61b6\u3084\u5224\u65ad\u529b\u5411\u4e0a\u306e\u305f\u3081\u306b\u3001\u30a6\u30a9\u30fc\u30e0\u30a2\u30c3\u30d7\u306e\u65b9\u6cd5\u3092\u8abf\u6574<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>17.2. \u7af6\u6280\u5f8c\u306e\u30ea\u30ab\u30d0\u30ea\u30fc\u6226\u7565<\/strong><\/h3>\n\n\n\n<p>\u8a66\u5408\u5f8c\u306e\u75b2\u52b4\u56de\u5fa9\u3082\u907a\u4f1d\u5b50\u578b\u306b\u3088\u3063\u3066\u9069\u5207\u306a\u65b9\u6cd5\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7b4b\u640d\u50b7\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u30bf\u30a4\u30d7\uff08CKM A\u578b\uff09<\/strong> \u2192 \u30a2\u30a4\u30b7\u30f3\u30b0\uff0b\u30a2\u30df\u30ce\u9178\u88dc\u7d66\u304c\u52b9\u679c\u7684<\/li>\n\n\n\n<li><strong>\u708e\u75c7\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u30bf\u30a4\u30d7\uff08IL6 C\/C\u578b\uff09<\/strong> \u2192 \u6297\u708e\u75c7\u98df\u54c1\uff08\u30aa\u30e1\u30ac3\u3001\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\uff09\u3092\u6442\u53d6<\/li>\n\n\n\n<li><strong>\u56de\u5fa9\u304c\u65e9\u3044\u30bf\u30a4\u30d7\uff08NR3C1 G\/G\u578b\uff09<\/strong> \u2192 \u9ad8\u8ca0\u8377\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u77ed\u671f\u9593\u3067\u518d\u958b\u53ef\u80fd<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>18. \u907a\u4f1d\u5b50\u60c5\u5831\u306e\u793e\u4f1a\u7684\u6d3b\u7528\u3068\u8ab2\u984c<\/strong><\/h2>\n\n\n\n<p>\u30b9\u30dd\u30fc\u30c4\u3084\u30d5\u30a3\u30c3\u30c8\u30cd\u30b9\u696d\u754c\u3060\u3051\u3067\u306a\u304f\u3001\u5065\u5eb7\u7ba1\u7406\u5168\u822c\u306b\u304a\u3044\u3066\u3082\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d3b\u7528\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u4e00\u65b9\u3067\u3001\u3044\u304f\u3064\u304b\u306e\u793e\u4f1a\u7684\u8ab2\u984c\u3082\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>18.1. \u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306e\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u4fdd\u8b77<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306f\u975e\u5e38\u306b\u500b\u4eba\u6027\u306e\u9ad8\u3044\u30c7\u30fc\u30bf\u3067\u3042\u308a\u3001\u614e\u91cd\u306b\u7ba1\u7406\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c7\u30fc\u30bf\u6f0f\u6d29\u306e\u30ea\u30b9\u30af<\/strong> \u2192 \u4e0d\u6b63\u30a2\u30af\u30bb\u30b9\u306b\u3088\u308b\u60c5\u5831\u6d41\u51fa\u3092\u9632\u3050\u305f\u3081\u306e\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3\u5bfe\u7b56\u304c\u5fc5\u8981<\/li>\n\n\n\n<li><strong>\u4fdd\u967a\u3084\u96c7\u7528\u3078\u306e\u5f71\u97ff<\/strong> \u2192 \u907a\u4f1d\u60c5\u5831\u3092\u7406\u7531\u306b\u5dee\u5225\u304c\u767a\u751f\u3057\u306a\u3044\u3088\u3046\u3001\u6cd5\u5f8b\u306b\u3088\u308b\u898f\u5236\u304c\u6c42\u3081\u3089\u308c\u308b<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>18.2. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u8aa4\u89e3\u3068\u502b\u7406\u7684\u8ab2\u984c<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u306f\u300c\u53ef\u80fd\u6027\u300d\u3092\u793a\u3059\u3082\u306e\u3067\u3042\u308a\u3001\u6c7a\u5b9a\u8ad6\u7684\u306b\u89e3\u91c8\u3059\u308b\u306e\u306f\u8aa4\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u300c\u3053\u306e\u907a\u4f1d\u5b50\u304c\u3042\u308b\u304b\u3089\u30d7\u30ed\u9078\u624b\u306b\u306a\u308c\u308b\u300d\u3068\u3044\u3046\u8aa4\u89e3\u3092\u9632\u3050<\/strong><\/li>\n\n\n\n<li><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u57fa\u306b\u3057\u305f\u6975\u7aef\u306a\u6307\u5c0e\u65b9\u6cd5\u3092\u907f\u3051\u308b<\/strong><\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator 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class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>1. \u904b\u52d5\u9069\u6027\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2 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[&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":2514,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6,1],"tags":[52,59,36,49,34],"class_list":["post-573","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-basicknowledge","category-latest-technology","tag-dna-test","tag-59","tag-gene-testing","tag-gene-analysis","tag-genetic-identification"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/573","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/comments?post=573"}],"version-history":[{"count":4,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/573\/revisions"}],"predecessor-version":[{"id":8545,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/573\/revisions\/8545"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media\/2514"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media?parent=573"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/categories?post=573"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/tags?post=573"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}