{"id":610,"date":"2024-11-26T03:47:02","date_gmt":"2024-11-26T03:47:02","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=610"},"modified":"2025-02-20T03:29:34","modified_gmt":"2025-02-20T03:29:34","slug":"endurance-genetics","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/endurance-genetics\/","title":{"rendered":"\u907a\u4f1d\u5b50\u60c5\u5831\u3068\u6301\u4e45\u529b\u306e\u95a2\u4fc2\u6027"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u306f\u3058\u3081\u306b<\/strong><\/h2>\n\n\n\n<p>\u30b9\u30dd\u30fc\u30c4\u79d1\u5b66\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u6301\u4e45\u529b\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u9023\u6027\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u591a\u578b\u304c\u6301\u4e45\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u6301\u4e45\u529b\u306b\u95a2\u9023\u3059\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50\u3068\u305d\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066\u3001\u6700\u65b0\u306e\u7814\u7a76\u7d50\u679c\u3092\u4ea4\u3048\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u6301\u4e45\u529b\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u9023\u6027<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\uff08ACE\uff09\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>ACE\u907a\u4f1d\u5b50\u306f\u3001\u8840\u5727\u8abf\u7bc0\u3084\u96fb\u89e3\u8cea\u30d0\u30e9\u30f3\u30b9\u306b\u95a2\u4e0e\u3059\u308b\u9175\u7d20\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306b\u306f\u3001\u633f\u5165\uff08I\uff09\u578b\u3068\u6b20\u5931\uff08D\uff09\u578b\u306e\u591a\u578b\u304c\u5b58\u5728\u3057\u3001\u6301\u4e45\u529b\u3068\u306e\u95a2\u9023\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001I\u578b\u3092\u6301\u3064\u500b\u4f53\u306f\u6301\u4e45\u7684\u80fd\u529b\u306b\u512a\u308c\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u03b1-\u30a2\u30af\u30c1\u30cb\u30f33\uff08ACTN3\uff09\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>ACTN3\u907a\u4f1d\u5b50\u306f\u3001\u9aa8\u683c\u7b4b\u306e\u901f\u7b4b\u7dda\u7dad\u306b\u5b58\u5728\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306b\u306fR\u578b\u3068X\u578b\u304c\u3042\u308a\u3001XX\u578b\u306e\u500b\u4f53\u306f\u03b1-\u30a2\u30af\u30c1\u30cb\u30f33\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6b20\u640d\u3057\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u306b\u3088\u308c\u3070\u3001XX\u578b\u306e\u4eba\u3005\u306f\u6301\u4e45\u7684\u904b\u52d5\u80fd\u529b\u306b\u512a\u308c\u3066\u3044\u308b\u50be\u5411\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\uff08mtDNA\uff09\u591a\u578b<\/strong><\/h3>\n\n\n\n<p>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306f\u30a8\u30cd\u30eb\u30ae\u30fc\u751f\u7523\u306e\u4e2d\u5fc3\u3067\u3042\u308a\u3001\u305d\u306eDNA\u306e\u591a\u578b\u304c\u6301\u4e45\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6bcd\u7cfb\u907a\u4f1d\u3059\u308bmtDNA\u306e\u500b\u4eba\u5dee\u304c\u3001\u6301\u4e45\u7cfb\u3060\u3051\u3067\u306a\u304f\u77ac\u767a\u7cfb\u306e\u80fd\u529b\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d3b\u7528\u3068\u502b\u7406\u7684\u8ab2\u984c<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6280\u8853\u304c\u9032\u6b69\u3057\u3001\u500b\u4eba\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u628a\u63e1\u3059\u308b\u3053\u3068\u304c\u5bb9\u6613\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u7af6\u6280\u9078\u629e\u306b\u304a\u3044\u3066\u907a\u4f1d\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u52d5\u304d\u304c\u898b\u3089\u308c\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u53d6\u308a\u6271\u3044\u306b\u306f\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u3084\u5dee\u5225\u306e\u554f\u984c\u306a\u3069\u3001\u502b\u7406\u7684\u306a\u8ab2\u984c\u3082\u5b58\u5728\u3057\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u3069\u306e\u3088\u3046\u306b\u6d3b\u7528\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u306f\u614e\u91cd\u306a\u691c\u8a0e\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u6301\u4e45\u529b\u306b\u95a2\u4e0e\u3059\u308b\u305d\u306e\u4ed6\u306e\u907a\u4f1d\u5b50<\/strong><\/h2>\n\n\n\n<p>\u6301\u4e45\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u907a\u4f1d\u5b50\u306f\u3001ACE\u3084ACTN3\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u907a\u4f1d\u5b50\u89e3\u6790\u6280\u8853\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u65b0\u305f\u306a\u6301\u4e45\u529b\u95a2\u9023\u907a\u4f1d\u5b50\u304c\u6b21\u3005\u3068\u767a\u898b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09PPARGC1A\u907a\u4f1d\u5b50\uff08\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u751f\u5408\u6210\u306e\u8abf\u7bc0\uff09<\/strong><\/h3>\n\n\n\n<p>PPARGC1A\uff08\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u5897\u6b96\u56e0\u5b50\u6d3b\u6027\u5316\u53d7\u5bb9\u4f53\u30ac\u30f3\u30de\u5171\u5f79\u56e0\u5b501\u03b1\uff09\u306f\u3001<strong>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u65b0\u751f\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3092\u8abf\u7bc0\u3059\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50<\/strong>\u3067\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u9ad8\u3044\u3068\u3001\u7b4b\u8089\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u5bc6\u5ea6\u304c\u5897\u52a0\u3057\u3001\u9178\u7d20\u6d88\u8cbb\u91cf\u304c\u5411\u4e0a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u4e0e\u3059\u308b\u6301\u4e45\u529b\u7279\u6027<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PPARGC1A\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong>\u306f\u3001\u9577\u6642\u9593\u306e\u6709\u9178\u7d20\u904b\u52d5\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n\n\n\n<li><strong>PPARGC1A\u306e\u4f4e\u767a\u73fe\u578b\u306e\u4eba<\/strong>\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u304c\u4f4e\u304f\u3001\u6301\u4e45\u529b\u3088\u308a\u3082\u77ac\u767a\u529b\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PPARGC1A\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u3001\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u306b\u591a\u304f\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09VEGFA\u907a\u4f1d\u5b50\uff08\u8840\u7ba1\u65b0\u751f\u306e\u4fc3\u9032\uff09<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/31747266_m-1024x683.jpg\" alt=\"\u30d1\u30fc\u30bd\u30ca\u30eb\u30ab\u30e9\u30fc\u30fb\u30aa\u30ec\u30f3\u30b8\" class=\"wp-image-6358\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31747266_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31747266_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31747266_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31747266_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31747266_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>VEGFA\uff08\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u5897\u6b96\u56e0\u5b50A\uff09\u306f\u3001\u8840\u7ba1\u306e\u65b0\u751f\u3092\u4fc3\u3057\u3001\u7b4b\u8089\u3078\u306e\u9178\u7d20\u4f9b\u7d66\u3092\u6700\u9069\u5316\u3059\u308b\u907a\u4f1d\u5b50\u3067\u3059\u3002\u6301\u4e45\u7684\u306a\u904b\u52d5\u3092\u3059\u308b\u305f\u3081\u306b\u306f\u3001<strong>\u5341\u5206\u306a\u8840\u6d41\u304c\u7b4b\u8089\u306b\u4f9b\u7d66\u3055\u308c\u308b\u3053\u3068\u304c\u4e0d\u53ef\u6b20<\/strong>\u3067\u3042\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u91cf\u304c\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u4e0e\u3059\u308b\u6301\u4e45\u529b\u7279\u6027<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>VEGFA\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong>\u306f\u3001\u6bdb\u7d30\u8840\u7ba1\u5bc6\u5ea6\u304c\u9ad8\u304f\u3001\u7b4b\u8089\u3078\u306e\u9178\u7d20\u4f9b\u7d66\u304c\u52b9\u7387\u7684\u3002<\/li>\n\n\n\n<li><strong>VEGFA\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong>\u306f\u3001\u6301\u4e45\u904b\u52d5\u6642\u306e\u9178\u7d20\u4f9b\u7d66\u304c\u5236\u9650\u3055\u308c\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>VEGFA\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3001\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u3068\u975e\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u9593\u3067\u6709\u610f\u306b\u7570\u306a\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09NRF2\u907a\u4f1d\u5b50\uff08\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306e\u5411\u4e0a\uff09<\/strong><\/h3>\n\n\n\n<p>NRF2\uff08\u6838\u56e0\u5b50\u30a8\u30ea\u30b9\u30ed\u30a4\u30c92\u95a2\u9023\u56e0\u5b502\uff09\u306f\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u304b\u3089\u7d30\u80de\u3092\u4fdd\u8b77\u3059\u308b\u50cd\u304d\u3092\u6301\u3064\u907a\u4f1d\u5b50\u3067\u3059\u3002\u6301\u4e45\u904b\u52d5\u3067\u306f\u5927\u91cf\u306e\u6d3b\u6027\u9178\u7d20\u304c\u767a\u751f\u3059\u308b\u305f\u3081\u3001<strong>\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3078\u306e\u8010\u6027\u304c\u6301\u4e45\u529b\u5411\u4e0a\u306e\u9375<\/strong>\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u4e0e\u3059\u308b\u6301\u4e45\u529b\u7279\u6027<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NRF2\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u4eba<\/strong>\u306f\u3001\u6301\u4e45\u904b\u52d5\u6642\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u5f37\u304f\u3001\u75b2\u52b4\u306e\u56de\u5fa9\u304c\u65e9\u3044\u3002<\/li>\n\n\n\n<li><strong>NRF2\u306e\u6d3b\u6027\u304c\u4f4e\u3044\u4eba<\/strong>\u306f\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u304f\u3001\u6301\u4e45\u904b\u52d5\u5f8c\u306e\u56de\u5fa9\u306b\u6642\u9593\u304c\u304b\u304b\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NRF2\u907a\u4f1d\u5b50\u306e\u9ad8\u6d3b\u6027\u578b\u306e\u4eba\u306f\u3001\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u9069\u5fdc\u304c\u826f\u597d\u3067\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u6301\u4e45\u529b\u3068\u907a\u4f1d\u5b50\u306e\u5b9f\u7528\u5316\uff1a\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u3005\u306b\u9069\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3092\u6700\u9069\u5316\u3057\u3001\u6301\u4e45\u529b\u3092\u52b9\u7387\u7684\u306b\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>ACE\u907a\u4f1d\u5b50\u578b\u3068\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u95a2\u4fc2<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>I\u578b\uff08\u6301\u4e45\u529b\u512a\u4f4d\u578b\uff09<\/strong> \u2192 \u9577\u6642\u9593\u306e\u6709\u9178\u7d20\u904b\u52d5\u306b\u9069\u5fdc\u3057\u3084\u3059\u3044\u3002\u30de\u30e9\u30bd\u30f3\u3084\u30c8\u30e9\u30a4\u30a2\u30b9\u30ed\u30f3\u5411\u304d\u3002<\/li>\n\n\n\n<li><strong>D\u578b\uff08\u77ac\u767a\u529b\u512a\u4f4d\u578b\uff09<\/strong> \u2192 \u7121\u9178\u7d20\u904b\u52d5\u306b\u9069\u5fdc\u3057\u3084\u3059\u304f\u3001\u77ed\u8ddd\u96e2\u8d70\u3084\u30a6\u30a7\u30a4\u30c8\u30ea\u30d5\u30c6\u30a3\u30f3\u30b0\u5411\u304d\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>ACTN3\u907a\u4f1d\u5b50\u578b\u3068\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u95a2\u4fc2<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>RR\u578b\uff08\u901f\u7b4b\u512a\u4f4d\uff09<\/strong> \u2192 \u30a4\u30f3\u30bf\u30fc\u30d0\u30eb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u30b9\u30d7\u30ea\u30f3\u30c8\u7cfb\u306e\u7af6\u6280\u306b\u6700\u9069\u3002<\/li>\n\n\n\n<li><strong>XX\u578b\uff08\u9045\u7b4b\u512a\u4f4d\uff09<\/strong> \u2192 LSD\uff08\u30ed\u30f3\u30b0\u30b9\u30ed\u30fc\u30c7\u30a3\u30b9\u30bf\u30f3\u30b9\uff09\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u52b9\u679c\u7684\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u5f37\u5316\u306e\u305f\u3081\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6226\u7565<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1920\" height=\"1280\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/3497051_m.jpg\" alt=\"\u30d7\u30e9\u30f3\u30af\u3059\u308b\u5973\u6027\" class=\"wp-image-6373\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3497051_m.jpg 1920w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3497051_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3497051_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3497051_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/3497051_m-1536x1024.jpg 1536w\" sizes=\"(max-width: 1920px) 100vw, 1920px\" \/><\/figure>\n\n\n\n<p>\u6301\u4e45\u529b\u5411\u4e0a\u306e\u9375\u3068\u306a\u308b\u306e\u304c\u3001<strong>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u52b9\u7387\u7684\u306a\u30a8\u30cd\u30eb\u30ae\u30fc\u751f\u7523\u80fd\u529b<\/strong>\u3067\u3059\u3002\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3001\u6700\u9069\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u9078\u629e\u3059\u308b\u3053\u3068\u3067\u3001\u52b9\u679c\u7684\u306b\u6301\u4e45\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u63a8\u5968\u3055\u308c\u308b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PPARGC1A\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 \u9ad8\u5f37\u5ea6\u30a4\u30f3\u30bf\u30fc\u30d0\u30eb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08HIIT\uff09\u304c\u52b9\u679c\u7684\u3002<\/li>\n\n\n\n<li><strong>VEGFA\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 \u9577\u6642\u9593\u306e\u4f4e\u5f37\u5ea6\u6709\u9178\u7d20\u904b\u52d5\u3067\u6bdb\u7d30\u8840\u7ba1\u306e\u5897\u52a0\u3092\u4fc3\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HIIT\u304cPPARGC1A\u306e\u767a\u73fe\u3092\u5897\u52a0\u3055\u305b\u3001\u6301\u4e45\u529b\u5411\u4e0a\u306b\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u6804\u990a\u6226\u7565<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u529b\u5411\u4e0a\u306b\u306f\u3001<strong>\u9069\u5207\u306a\u6804\u990a\u6442\u53d6\u304c\u4e0d\u53ef\u6b20<\/strong>\u3067\u3059\u3002\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u4eba\u306b\u6700\u9069\u306a\u6804\u990a\u6226\u7565\u3092\u69cb\u7bc9\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u306b\u57fa\u3065\u304f\u6804\u990a\u7ba1\u7406<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>VDR\u907a\u4f1d\u5b50\uff08\u30d3\u30bf\u30df\u30f3D\u53d7\u5bb9\u4f53\uff09\u306e\u5909\u7570\u304c\u3042\u308b\u4eba<\/strong> \u2192 \u30d3\u30bf\u30df\u30f3D\u306e\u5438\u53ce\u7387\u304c\u4f4e\u3044\u305f\u3081\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u6d3b\u7528\u3002<\/li>\n\n\n\n<li><strong>MCT1\u907a\u4f1d\u5b50\uff08\u4e73\u9178\u4ee3\u8b1d\uff09\u306e\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong> \u2192 \u4e73\u9178\u306e\u9664\u53bb\u80fd\u529b\u304c\u4f4e\u3044\u305f\u3081\u3001\u6297\u9178\u5316\u7269\u8cea\uff08\u30d3\u30bf\u30df\u30f3C\u30fbE\uff09\u306e\u6442\u53d6\u3092\u5f37\u5316\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d3\u30bf\u30df\u30f3D\u306e\u88dc\u7d66\u304c\u3001\u6301\u4e45\u529b\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u5411\u4e0a\u306b\u8ca2\u732e\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff084\uff09\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30ea\u30ab\u30d0\u30ea\u30fc\u30d7\u30ed\u30b0\u30e9\u30e0<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u529b\u5411\u4e0a\u306b\u306f\u3001<strong>\u9069\u5207\u306a\u30ea\u30ab\u30d0\u30ea\u30fc\uff08\u56de\u5fa9\uff09\u304c\u4e0d\u53ef\u6b20<\/strong>\u3067\u3059\u3002\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3001\u500b\u4eba\u306e\u56de\u5fa9\u529b\u306b\u5fdc\u3058\u305f\u30ea\u30ab\u30d0\u30ea\u30fc\u6226\u7565\u3092\u69cb\u7bc9\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30ea\u30ab\u30d0\u30ea\u30fc\u306e\u6700\u9069\u5316<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NRF2\u907a\u4f1d\u5b50\u306e\u9ad8\u6d3b\u6027\u578b\u306e\u4eba<\/strong> \u2192 \u4f4e\u9178\u7d20\u74b0\u5883\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3067\u56de\u5fa9\u529b\u3092\u5411\u4e0a\u3002<\/li>\n\n\n\n<li><strong>HSP70\u907a\u4f1d\u5b50\uff08\u30d2\u30fc\u30c8\u30b7\u30e7\u30c3\u30af\u30d7\u30ed\u30c6\u30a4\u30f3\uff09\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 \u30a2\u30a4\u30b7\u30f3\u30b0\u3084\u30b9\u30c8\u30ec\u30c3\u30c1\u3092\u91cd\u8996\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9178\u7d20\u30ab\u30d7\u30bb\u30eb\u304cNRF2\u306e\u6d3b\u6027\u3092\u9ad8\u3081\u3001\u6301\u4e45\u529b\u5411\u4e0a\u306b\u5bc4\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u6301\u4e45\u529b\u5411\u4e0a\u306e\u5b9f\u8df5\u7684\u30a2\u30d7\u30ed\u30fc\u30c1<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/31195305_m-1024x585.jpg\" alt=\"\u91ce\u83dc\u3092\u524d\u306b\u8aac\u660e\u3059\u308b\u6804\u990a\u58eb\" class=\"wp-image-4580\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31195305_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31195305_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31195305_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31195305_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31195305_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u6301\u4e45\u529b\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u305f\u3081\u306e\u500b\u5225\u5316\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<strong>\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3001\u6804\u990a\u7ba1\u7406\u3001\u30ea\u30ab\u30d0\u30ea\u30fc\u3001\u74b0\u5883\u9069\u5fdc<\/strong>\u3068\u3044\u3063\u305f\u8981\u7d20\u3092\u907a\u4f1d\u5b50\u30ec\u30d9\u30eb\u3067\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u5411\u4e0a\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3068ACE\u907a\u4f1d\u5b50\u578b<\/strong><\/h4>\n\n\n\n<p>ACE\u907a\u4f1d\u5b50\u306b\u306f**I\u578b\uff08\u6301\u4e45\u529b\u512a\u4f4d\uff09<strong>\u3068<\/strong>D\u578b\uff08\u77ac\u767a\u529b\u512a\u4f4d\uff09**\u304c\u3042\u308a\u307e\u3059\u3002\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3092\u63a1\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u52b9\u7387\u7684\u306b\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>I\/I\u578b\uff08\u6301\u4e45\u529b\u5411\u4e0a\u306b\u9069\u5fdc\uff09<\/strong> \u2192 <strong>\u9577\u6642\u9593\u306e\u4f4e\u5f37\u5ea6\u6709\u9178\u7d20\u904b\u52d5\uff08LSD\uff09\u304c\u6700\u9069<\/strong>\u3002<\/li>\n\n\n\n<li><strong>I\/D\u578b\uff08\u6301\u4e45\u529b\u3068\u77ac\u767a\u529b\u306e\u30d0\u30e9\u30f3\u30b9\u578b\uff09<\/strong> \u2192 <strong>\u30a4\u30f3\u30bf\u30fc\u30d0\u30eb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u30c6\u30f3\u30dd\u8d70\u304c\u52b9\u679c\u7684<\/strong>\u3002<\/li>\n\n\n\n<li><strong>D\/D\u578b\uff08\u77ac\u767a\u529b\u5bc4\u308a\uff09<\/strong> \u2192 <strong>\u6301\u4e45\u529b\u5411\u4e0a\u306b\u306fHIIT\uff08\u9ad8\u5f37\u5ea6\u30a4\u30f3\u30bf\u30fc\u30d0\u30eb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff09\u304c\u5fc5\u8981<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>ACTN3\u907a\u4f1d\u5b50\u3068\u7b4b\u7dda\u7dad\u306e\u9069\u5fdc<\/strong><\/h4>\n\n\n\n<p>ACTN3\u907a\u4f1d\u5b50\u306e\u578b\u306f\u3001\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u9069\u5fdc\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>XX\u578b\uff08\u9045\u7b4b\u512a\u4f4d\uff09<\/strong> \u2192 <strong>\u9577\u8ddd\u96e2\u8d70\u3084\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u304c\u9069\u3057\u3066\u3044\u308b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>RR\u578b\uff08\u901f\u7b4b\u512a\u4f4d\uff09<\/strong> \u2192 <strong>\u6301\u4e45\u529b\u5411\u4e0a\u306b\u306f\u7b4b\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\uff0b\u6709\u9178\u7d20\u904b\u52d5\uff09\u304c\u52b9\u679c\u7684<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>ACTN3\u306eXX\u578b\u3092\u6301\u3064\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u6301\u4e45\u529b\u7af6\u6280\u3067\u512a\u308c\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u767a\u63ee\u3059\u308b\u50be\u5411\u304c\u3042\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u74b0\u5883\u9069\u5fdc\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u529b\u5411\u4e0a\u306b\u306f\u3001<strong>\u74b0\u5883\u9069\u5fdc\u80fd\u529b\u304c\u91cd\u8981<\/strong>\u3067\u3059\u3002\u6a19\u9ad8\u306e\u9ad8\u3044\u5834\u6240\u3067\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08\u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff09\u3084\u6691\u71b1\u9806\u5316\u306a\u3069\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3066\u9069\u5fdc\u80fd\u529b\u3092\u9ad8\u3081\u308b\u65b9\u6cd5\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>HIF1A\u907a\u4f1d\u5b50\u3068\u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/h4>\n\n\n\n<p>HIF1A\uff08\u4f4e\u9178\u7d20\u8a98\u5c0e\u56e0\u5b501\u03b1\uff09\u907a\u4f1d\u5b50\u306f\u3001\u4f4e\u9178\u7d20\u74b0\u5883\u3067\u306e\u9069\u5fdc\u80fd\u529b\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HIF1A\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 \u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u9069\u5fdc\u304c\u901f\u304f\u3001\u9178\u7d20\u904b\u642c\u80fd\u529b\u304c\u5411\u4e0a\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>HIF1A\u306e\u6d3b\u6027\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 \u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u9069\u5fdc\u306b\u6642\u9593\u304c\u304b\u304b\u308b\u305f\u3081\u3001\u4e8b\u524d\u306b\u4f4e\u9178\u7d20\u74b0\u5883\u3067\u306e\u6163\u3089\u3057\u304c\u5fc5\u8981\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>UCP2\u907a\u4f1d\u5b50\u3068\u6691\u71b1\u9806\u5316<\/strong><\/h4>\n\n\n\n<p>UCP2\uff08\u8131\u5171\u5f79\u30bf\u30f3\u30d1\u30af\u8cea2\uff09\u907a\u4f1d\u5b50\u306f\u3001<strong>\u4f53\u6e29\u8abf\u7bc0\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306b\u95a2\u4e0e<\/strong>\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>UCP2\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 \u6691\u71b1\u74b0\u5883\u306b\u5f37\u304f\u3001\u9577\u6642\u9593\u306e\u6301\u4e45\u904b\u52d5\u304c\u53ef\u80fd\u3002<\/li>\n\n\n\n<li><strong>UCP2\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 \u6691\u71b1\u74b0\u5883\u3067\u306e\u6301\u4e45\u904b\u52d5\u304c\u56f0\u96e3\u306a\u305f\u3081\u3001\u4e8b\u524d\u306b\u6691\u71b1\u9806\u5316\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u5fc5\u8981\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HIF1A\u306e\u9ad8\u767a\u73fe\u578b\u3092\u6301\u3064\u30de\u30e9\u30bd\u30f3\u9078\u624b\u306f\u3001\u6a19\u9ad8\u306e\u9ad8\u3044\u74b0\u5883\u3067\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u304c\u5411\u4e0a\u3057\u3084\u3059\u3044<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u907a\u4f1d\u5b50\u578b\u306b\u57fa\u3065\u3044\u305f\u6804\u990a\u6226\u7565\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"512\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/30775587_m-1024x512.jpg\" alt=\"\u30d3\u30b8\u30cd\u30b9\u3000\u30b0\u30e9\u30d5\u3000\u30c1\u30e3\u30fc\u30c8\u3000\u30d0\u30ca\u30fc\u3000\u4fef\u77b0\" class=\"wp-image-6019\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30775587_m-1024x512.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30775587_m-300x150.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30775587_m-768x384.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30775587_m-1536x768.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/30775587_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u6301\u4e45\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u305f\u3081\u306b\u306f\u3001\u9069\u5207\u306a\u6804\u990a\u6442\u53d6\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u4eba\u306b\u9069\u3057\u305f\u6804\u990a\u8a08\u753b\u3092\u7acb\u3066\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3068PPARGC1A\u907a\u4f1d\u5b50<\/strong><\/h4>\n\n\n\n<p>PPARGC1A\u907a\u4f1d\u5b50\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u7523\u751f\u3092\u8abf\u7bc0\u3059\u308b\u305f\u3081\u3001\u6301\u4e45\u529b\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PPARGC1A\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 <strong>\u9ad8\u70ad\u6c34\u5316\u7269\u98df\uff08\u30a8\u30f3\u30c7\u30e5\u30e9\u30f3\u30b9\u5411\u3051\uff09\u304c\u9069\u3057\u3066\u3044\u308b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>PPARGC1A\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 <strong>\u9ad8\u8102\u8cea\u98df\uff08\u30b1\u30c8\u30f3\u98df\uff09\u304c\u30a8\u30cd\u30eb\u30ae\u30fc\u52b9\u7387\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>MCT1\u907a\u4f1d\u5b50\u3068\u4e73\u9178\u4ee3\u8b1d<\/strong><\/h4>\n\n\n\n<p>MCT1\uff08\u30e2\u30ce\u30ab\u30eb\u30dc\u30f3\u9178\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc1\uff09\u907a\u4f1d\u5b50\u306f\u3001\u4e73\u9178\u306e\u9664\u53bb\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MCT1\u306e\u6a5f\u80fd\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 \u4e73\u9178\u306e\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u304c\u901f\u304f\u3001\u9ad8\u5f37\u5ea6\u6301\u4e45\u904b\u52d5\u306b\u9069\u5fdc\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>MCT1\u306e\u6a5f\u80fd\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 \u4e73\u9178\u304c\u84c4\u7a4d\u3057\u3084\u3059\u3044\u305f\u3081\u3001\u6297\u9178\u5316\u7269\u8cea\uff08\u30d3\u30bf\u30df\u30f3C\u30fbE\uff09\u306e\u6442\u53d6\u304c\u63a8\u5968\u3055\u308c\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MCT1\u306e\u9ad8\u767a\u73fe\u578b\u3092\u6301\u3064\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u9ad8\u5f37\u5ea6\u6301\u4e45\u904b\u52d5\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u304c\u5411\u4e0a\u3059\u308b\u50be\u5411\u304c\u3042\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff084\uff09\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30ea\u30ab\u30d0\u30ea\u30fc\u30d7\u30ed\u30b0\u30e9\u30e0<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u529b\u5411\u4e0a\u306b\u306f\u3001\u9069\u5207\u306a\u30ea\u30ab\u30d0\u30ea\u30fc\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3001\u500b\u4eba\u306e\u56de\u5fa9\u529b\u306b\u5fdc\u3058\u305f\u30ea\u30ab\u30d0\u30ea\u30fc\u6226\u7565\u3092\u6700\u9069\u5316\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>NRF2\u907a\u4f1d\u5b50\u3068\u6297\u9178\u5316\u80fd\u529b<\/strong><\/h4>\n\n\n\n<p>NRF2\u306f\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u304b\u3089\u7d30\u80de\u3092\u4fdd\u8b77\u3059\u308b\u50cd\u304d\u3092\u6301\u3064\u907a\u4f1d\u5b50\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NRF2\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 <strong>\u6301\u4e45\u904b\u52d5\u5f8c\u306e\u56de\u5fa9\u304c\u65e9\u304f\u3001\u30b9\u30c8\u30ec\u30c3\u30c1\u3084\u4f4e\u5f37\u5ea6\u904b\u52d5\u3067\u306e\u56de\u5fa9\u304c\u52b9\u679c\u7684<\/strong>\u3002<\/li>\n\n\n\n<li><strong>NRF2\u306e\u6d3b\u6027\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 <strong>\u6297\u9178\u5316\u7269\u8cea\uff08\u7dd1\u8336\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3001\u30d3\u30bf\u30df\u30f3E\uff09\u306e\u6442\u53d6\u304c\u63a8\u5968\u3055\u308c\u308b<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>HSP70\u907a\u4f1d\u5b50\u3068\u71b1\u30b7\u30e7\u30c3\u30af\u30d7\u30ed\u30c6\u30a4\u30f3<\/strong><\/h4>\n\n\n\n<p>HSP70\uff08\u30d2\u30fc\u30c8\u30b7\u30e7\u30c3\u30af\u30d7\u30ed\u30c6\u30a4\u30f3\uff09\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3068\u56de\u5fa9\u529b\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HSP70\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 **\u6691\u71b1\u74b0\u5883\u3084\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u5411\u4e0a\u306e\u5b9f\u8df5<\/strong><\/h2>\n\n\n\n<p>\u6301\u4e45\u529b\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u305f\u3081\u306b\u306f\u3001<strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u30a2\u30d7\u30ed\u30fc\u30c1<\/strong>\u304c\u91cd\u8981\u3067\u3059\u3002\u3053\u3053\u3067\u306f\u3001<strong>\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3001\u6804\u990a\u7ba1\u7406\u3001\u56de\u5fa9\u30d7\u30e9\u30f3\u3001\u74b0\u5883\u9069\u5fdc<\/strong>\u3068\u3044\u3063\u305f\u5b9f\u8df5\u7684\u306a\u6226\u7565\u3092\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u6301\u4e45\u529b\u5411\u4e0a\u306e\u305f\u3081\u306e\u907a\u4f1d\u5b50\u578b\u5225\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/28462699_m-1024x683.jpg\" alt=\"\u30de\u30e9\u30bd\u30f3\u5927\u4f1a\u3067\u30b4\u30fc\u30eb\u3059\u308b\u77ac\u9593\" class=\"wp-image-5507\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/28462699_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/28462699_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/28462699_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/28462699_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/28462699_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u578b\u3054\u3068\u306b\u9069\u5207\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3092\u9078\u629e\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u3088\u308a\u52b9\u679c\u7684\u306b\u6301\u4e45\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b<\/strong>\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>ACE\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30e9\u30f3<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>I\/I\u578b\uff08\u6301\u4e45\u529b\u578b\uff09<\/strong> \u2192 <strong>\u9577\u6642\u9593\u306e\u4f4e\u5f37\u5ea6\u6709\u9178\u7d20\u904b\u52d5\uff08LSD\uff09\u3092\u4e2d\u5fc3\u306b<\/strong>\u3002\u30de\u30e9\u30bd\u30f3\u3084\u30a6\u30eb\u30c8\u30e9\u30de\u30e9\u30bd\u30f3\u306b\u6700\u9069\u3002<\/li>\n\n\n\n<li><strong>I\/D\u578b\uff08\u30d0\u30e9\u30f3\u30b9\u578b\uff09<\/strong> \u2192 <strong>\u6301\u4e45\u529b\u3068\u7b4b\u529b\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong>\uff08\u4f8b\uff1a\u30c6\u30f3\u30dd\u8d70\uff0b\u7b4b\u30c8\u30ec\uff09\u3002\u30c8\u30e9\u30a4\u30a2\u30b9\u30ed\u30f3\u5411\u304d\u3002<\/li>\n\n\n\n<li><strong>D\/D\u578b\uff08\u77ac\u767a\u529b\u578b\uff09<\/strong> \u2192 <strong>HIIT\u3084\u30a4\u30f3\u30bf\u30fc\u30d0\u30eb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u91cd\u8996<\/strong>\u3057\u3001\u6301\u4e45\u529b\u3092\u88dc\u5f37\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>ACTN3\u907a\u4f1d\u5b50\u3068\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>XX\u578b\uff08\u9045\u7b4b\u512a\u4f4d\uff09<\/strong> \u2192 <strong>\u9577\u8ddd\u96e2\u30e9\u30f3\u3084\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u304c\u52b9\u679c\u7684<\/strong>\u3002<\/li>\n\n\n\n<li><strong>RR\u578b\uff08\u901f\u7b4b\u512a\u4f4d\uff09<\/strong> \u2192 <strong>\u77ed\u8ddd\u96e2\u30e9\u30f3\uff0b\u7b4b\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08\u30b9\u30af\u30ef\u30c3\u30c8\u3001\u30e9\u30f3\u30b8\uff09\u3092\u7d44\u307f\u5408\u308f\u305b\u308b<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>ACTN3\u306eXX\u578b\u3092\u6301\u3064\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u6301\u4e45\u529b\u7af6\u6280\u3067\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u304c\u9ad8\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u6804\u990a\u7ba1\u7406\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4f9b\u7d66\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u529b\u3092\u9ad8\u3081\u308b\u305f\u3081\u306b\u306f\u3001\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u6804\u990a\u6226\u7565\u3092\u63a1\u7528\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u6804\u990a\u6442\u53d6\u8a08\u753b<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PPARGC1A\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 <strong>\u9ad8\u70ad\u6c34\u5316\u7269\u98df\uff08\u7cd6\u8cea\u4e2d\u5fc3\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u88dc\u7d66\uff09\u304c\u9069\u3057\u3066\u3044\u308b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>PPARGC1A\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 <strong>\u9ad8\u8102\u8cea\u98df\uff08\u30b1\u30c8\u30f3\u4f53\u30a8\u30cd\u30eb\u30ae\u30fc\u6226\u7565\uff09\u304c\u6709\u52b9<\/strong>\u3002<\/li>\n\n\n\n<li><strong>MCT1\u306e\u4f4e\u767a\u73fe\u578b\u306e\u4eba<\/strong> \u2192 <strong>\u6297\u9178\u5316\u98df\u54c1\uff08\u30d3\u30bf\u30df\u30f3C\u30fbE\uff09\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3057\u3001\u4e73\u9178\u4ee3\u8b1d\u3092\u4fc3\u9032<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u6301\u4e45\u529b\u3092\u652f\u3048\u308b\u91cd\u8981\u306a\u6804\u990a\u7d20<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9244\u5206\uff08HFE\u907a\u4f1d\u5b50\u306b\u95a2\u9023\uff09<\/strong> \u2192 <strong>\u9178\u7d20\u904b\u642c\u80fd\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u305f\u3081\u3001\u8d64\u8eab\u8089\u3084\u30ec\u30d0\u30fc\u3092\u6442\u53d6<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u30d3\u30bf\u30df\u30f3D\uff08VDR\u907a\u4f1d\u5b50\u306b\u95a2\u9023\uff09<\/strong> \u2192 <strong>\u7b4b\u529b\u7dad\u6301\u3068\u514d\u75ab\u5f37\u5316\u306e\u305f\u3081\u306b\u65e5\u5149\u6d74\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u6d3b\u7528<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\uff08PPAR\u03b1\u907a\u4f1d\u5b50\u306b\u95a2\u9023\uff09<\/strong> \u2192 <strong>\u708e\u75c7\u6291\u5236\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306e\u6700\u9069\u5316\u306b\u6709\u52b9<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PPARGC1A\u306e\u9ad8\u767a\u73fe\u578b\u306e\u4eba\u306f\u3001\u9ad8\u70ad\u6c34\u5316\u7269\u98df\u304c\u6301\u4e45\u529b\u5411\u4e0a\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u30ea\u30ab\u30d0\u30ea\u30fc\u6226\u7565\u3068\u75b2\u52b4\u56de\u5fa9\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/31437210_m-1024x683.jpg\" alt=\"\u30b9\u30c8\u30ec\u30c3\u30c1\u3092\u3059\u308b\u5973\u6027\" class=\"wp-image-5841\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31437210_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31437210_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31437210_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31437210_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31437210_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3001\u500b\u4eba\u306b\u5408\u3063\u305f\u30ea\u30ab\u30d0\u30ea\u30fc\u6226\u7565\u3092\u5c0e\u5165\u3059\u308b\u3053\u3068\u3067\u3001\u6301\u4e45\u529b\u306e\u6301\u7d9a\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>NRF2\u907a\u4f1d\u5b50\u3068\u6297\u9178\u5316\u80fd\u529b<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NRF2\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 <strong>\u6301\u4e45\u904b\u52d5\u5f8c\u306e\u56de\u5fa9\u304c\u65e9\u3044\u305f\u3081\u3001\u30b9\u30c8\u30ec\u30c3\u30c1\u3084\u30de\u30c3\u30b5\u30fc\u30b8\u3067\u306e\u56de\u5fa9\u304c\u6709\u52b9<\/strong>\u3002<\/li>\n\n\n\n<li><strong>NRF2\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 <strong>\u6297\u9178\u5316\u7269\u8cea\uff08\u7dd1\u8336\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3001\u30d3\u30bf\u30df\u30f3E\uff09\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3057\u3001\u75b2\u52b4\u56de\u5fa9\u3092\u30b5\u30dd\u30fc\u30c8<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>HSP70\u907a\u4f1d\u5b50\u3068\u71b1\u30b7\u30e7\u30c3\u30af\u30d7\u30ed\u30c6\u30a4\u30f3<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HSP70\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 <strong>\u6691\u71b1\u74b0\u5883\u3084\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e\u56de\u5fa9\u304c\u901f\u3044<\/strong>\u3002<\/li>\n\n\n\n<li><strong>HSP70\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 <strong>\u30a2\u30a4\u30b7\u30f3\u30b0\u3084\u4f4e\u6e29\u30b5\u30a6\u30ca\u3092\u5229\u7528\u3057\u3066\u56de\u5fa9\u3092\u4fc3\u9032<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NRF2\u907a\u4f1d\u5b50\u306e\u9ad8\u767a\u73fe\u578b\u3092\u6301\u3064\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u6301\u4e45\u904b\u52d5\u5f8c\u306e\u56de\u5fa9\u304c\u65e9\u3044\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff084\uff09\u74b0\u5883\u9069\u5fdc\u3068\u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u6d3b\u7528<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u529b\u5411\u4e0a\u306b\u306f\u3001\u74b0\u5883\u9069\u5fdc\u80fd\u529b\u3082\u91cd\u8981\u3067\u3059\u3002\u7279\u306b\u3001<strong>\u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306f\u6301\u4e45\u529b\u5f37\u5316\u306b\u5927\u304d\u304f\u8ca2\u732e\u3059\u308b<\/strong>\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>HIF1A\u907a\u4f1d\u5b50\u3068\u9178\u7d20\u9069\u5fdc<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HIF1A\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 <strong>\u9ad8\u5730\u74b0\u5883\u306b\u9069\u5fdc\u3057\u3084\u3059\u304f\u3001\u9178\u7d20\u904b\u642c\u80fd\u529b\u304c\u5411\u4e0a\u3057\u3084\u3059\u3044<\/strong>\u3002<\/li>\n\n\n\n<li><strong>HIF1A\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 <strong>\u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u9069\u5fdc\u306b\u6642\u9593\u304c\u304b\u304b\u308b\u305f\u3081\u3001\u4e8b\u524d\u306b\u4f4e\u9178\u7d20\u74b0\u5883\u3067\u306e\u6163\u3089\u3057\u304c\u5fc5\u8981<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>UCP2\u907a\u4f1d\u5b50\u3068\u6691\u71b1\u9806\u5316<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>UCP2\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 <strong>\u6691\u71b1\u74b0\u5883\u306b\u5f37\u304f\u3001\u9577\u6642\u9593\u306e\u6301\u4e45\u904b\u52d5\u304c\u53ef\u80fd<\/strong>\u3002<\/li>\n\n\n\n<li><strong>UCP2\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 <strong>\u6691\u71b1\u9806\u5316\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u53d6\u308a\u5165\u308c\u3001\u4f53\u6e29\u8abf\u7bc0\u6a5f\u80fd\u3092\u5f37\u5316<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HIF1A\u306e\u9ad8\u767a\u73fe\u578b\u3092\u6301\u3064\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e\u6301\u4e45\u529b\u5411\u4e0a\u304c\u9855\u8457\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u6301\u4e45\u529b\u5411\u4e0a\u306b\u304a\u3051\u308b\u907a\u4f1d\u5b50\u89e3\u6790\u306e\u672a\u6765<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/31838185_m-1024x683.jpg\" alt=\"\u30b8\u30e0\u3067\u30b9\u30de\u30fc\u30c8\u30a6\u30a9\u30c3\u30c1\u3092\u64cd\u4f5c\u3059\u308b\u7537\u6027\" class=\"wp-image-6124\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31838185_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31838185_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31838185_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31838185_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31838185_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u89e3\u6790\u6280\u8853\u304c\u9032\u5316\u3057\u3001\u3088\u308a\u6b63\u78ba\u306b\u6301\u4e45\u529b\u306e\u30dd\u30c6\u30f3\u30b7\u30e3\u30eb\u3092\u4e88\u6e2c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>AI\u3092\u6d3b\u7528\u3057\u305f\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>AI\u304c\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3092\u89e3\u6790\u3057\u3001\u500b\u5225\u306b\u6700\u9069\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30e1\u30cb\u30e5\u30fc\u3092\u63d0\u6848<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u751f\u4f53\u30c7\u30fc\u30bf\u3092\u53d6\u5f97\u3057\u3001\u75b2\u52b4\u3084\u56de\u5fa9\u72b6\u6cc1\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u306e\u53ef\u80fd\u6027<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CRISPR\u6280\u8853\u3092\u7528\u3044\u305f\u6301\u4e45\u529b\u5411\u4e0a\u306e\u305f\u3081\u306e\u907a\u4f1d\u5b50\u8abf\u6574\u306e\u7814\u7a76<\/strong>\u304c\u9032\u884c\u4e2d\u3002<\/li>\n\n\n\n<li><strong>\u5c06\u6765\u7684\u306b\u306f\u3001\u6301\u4e45\u529b\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u305f\u533b\u7642\u6280\u8853\u304c\u958b\u767a\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>AI\u3068\u907a\u4f1d\u5b50\u89e3\u6790\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u4e88\u6e2c\u304c\u3001\u5f93\u6765\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6307\u6a19\u3088\u308a\u3082\u7cbe\u5ea6\u304c\u9ad8\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u5b9f\u8df5\u6226\u7565<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u7528\u3044\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6226\u7565\u306f\u3001\u30b9\u30dd\u30fc\u30c4\u79d1\u5b66\u306e\u767a\u5c55\u3068\u3068\u3082\u306b\u6025\u901f\u306b\u9032\u5316\u3057\u3066\u3044\u307e\u3059\u3002\u500b\u3005\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u7406\u89e3\u3057\u3001\u305d\u308c\u306b\u9069\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3092\u63a1\u7528\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u6301\u4e45\u529b\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u3053\u3068\u304c\u53ef\u80fd<\/strong>\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f37\u5ea6\u3068\u56de\u5fa9\u6642\u9593\u306e\u8abf\u6574<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u3068\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f37\u5ea6<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>ACE I\/I\u578b\uff08\u6301\u4e45\u529b\u7279\u5316\u578b\uff09<\/strong> \u2192 **\u4f4e\u5f37\u5ea6\u9577\u6642\u9593\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff0860\u301c70% VO2max\uff09**\u304c\u6700\u9069\u3002<\/li>\n\n\n\n<li><strong>ACE D\/D\u578b\uff08\u77ac\u767a\u529b\u578b\uff09<\/strong> \u2192 <strong>\u9ad8\u5f37\u5ea6\u30a4\u30f3\u30bf\u30fc\u30d0\u30eb\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\uff08HIIT\uff09\u3092\u53d6\u308a\u5165\u308c\u3001\u6301\u4e45\u529b\u3092\u88dc\u5f37<\/strong>\u3002<\/li>\n\n\n\n<li><strong>ACTN3 XX\u578b\uff08\u9045\u7b4b\u512a\u4f4d\u578b\uff09<\/strong> \u2192 <strong>\u9577\u6642\u9593\u306e\u4e00\u5b9a\u30da\u30fc\u30b9\u30e9\u30f3\u30cb\u30f3\u30b0\u3084\u30ed\u30f3\u30b0\u30e9\u30a4\u30c9\u306b\u9069\u5fdc<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u3068\u56de\u5fa9\u6642\u9593<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NRF2\u9ad8\u767a\u73fe\u578b\uff08\u6297\u9178\u5316\u80fd\u529b\u304c\u9ad8\u3044\uff09<\/strong> \u2192 <strong>\u56de\u5fa9\u304c\u65e9\u3044\u305f\u3081\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u983b\u5ea6\u3092\u5897\u3084\u305b\u308b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>HSP70\u4f4e\u767a\u73fe\u578b\uff08\u71b1\u30b7\u30e7\u30c3\u30af\u8010\u6027\u304c\u4f4e\u3044\uff09<\/strong> \u2192 <strong>\u9ad8\u5f37\u5ea6\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306b\u5341\u5206\u306a\u4f11\u606f\u304c\u5fc5\u8981<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>ACE I\/I\u578b\u306e\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u9577\u6642\u9593\u306e\u6301\u4e45\u904b\u52d5\u306b\u304a\u3044\u3066\u512a\u308c\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u767a\u63ee\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u6301\u4e45\u529b\u5f37\u5316\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u9078\u629e<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/31179151_m-1-1024x683.jpg\" alt=\"\u3044\u308d\u3093\u306a\u8272\u306e\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\" class=\"wp-image-4707\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31179151_m-1-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31179151_m-1-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31179151_m-1-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31179151_m-1-1536x1025.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31179151_m-1.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u6804\u990a\u88dc\u52a9\u98df\u54c1\u306e\u9078\u629e\u306f\u3001\u6301\u4e45\u529b\u5411\u4e0a\u306b\u5927\u304d\u304f\u8ca2\u732e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u4e3b\u8981\u306a\u907a\u4f1d\u5b50\u578b\u3068\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u9069\u7528<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PPARGC1A\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 <strong>\u70ad\u6c34\u5316\u7269\u30ed\u30fc\u30c7\u30a3\u30f3\u30b0\uff08\u30b0\u30ea\u30b3\u30fc\u30b2\u30f3\u84c4\u7a4d\uff09\u3092\u91cd\u8996<\/strong>\u3002<\/li>\n\n\n\n<li><strong>MCT1\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba\uff08\u4e73\u9178\u9664\u53bb\u80fd\u529b\u304c\u4f4e\u3044\uff09<\/strong> \u2192 <strong>\u30af\u30a8\u30f3\u9178\u3084BCAA\u3092\u6442\u53d6\u3057\u3001\u6301\u4e45\u904b\u52d5\u5f8c\u306e\u75b2\u52b4\u3092\u8efd\u6e1b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>NRF2\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba\uff08\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u304c\u4f4e\u3044\uff09<\/strong> \u2192 <strong>\u30d3\u30bf\u30df\u30f3C\u30fbE\u3001\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u63a8\u5968\u3055\u308c\u308b\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30af\u30ec\u30a2\u30c1\u30f3<\/strong>\uff08\u77ac\u767a\u529b\u3068\u6301\u4e45\u529b\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u6700\u9069\u5316\uff09<\/li>\n\n\n\n<li><strong>\u30d9\u30fc\u30bf\u30a2\u30e9\u30cb\u30f3<\/strong>\uff08\u4e73\u9178\u8010\u6027\u3092\u5411\u4e0a\uff09<\/li>\n\n\n\n<li><strong>\u30ca\u30a4\u30a2\u30b7\u30f3\uff08\u30d3\u30bf\u30df\u30f3B3\uff09<\/strong>\uff08\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u3092\u30b5\u30dd\u30fc\u30c8\uff09<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d9\u30fc\u30bf\u30a2\u30e9\u30cb\u30f3\u306e\u6442\u53d6\u304c\u3001\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u904b\u52d5\u6301\u7d9a\u6642\u9593\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u907a\u4f1d\u5b50\u3068\u7761\u7720\u306e\u95a2\u4fc2\uff1a\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u56de\u5fa9\u3092\u6700\u5927\u5316<\/strong><\/h3>\n\n\n\n<p>\u7761\u7720\u306e\u8cea\u306f\u3001\u6301\u4e45\u529b\u5411\u4e0a\u306b\u4e0d\u53ef\u6b20\u306a\u8981\u7d20\u3067\u3059\u3002<strong>\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u7761\u7720\u30d1\u30bf\u30fc\u30f3\u3084\u56de\u5fa9\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059<\/strong>\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7761\u7720\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PER3\u907a\u4f1d\u5b50\uff08\u6982\u65e5\u30ea\u30ba\u30e0\u8abf\u6574\uff09<\/strong> \u2192 \u65e9\u5bdd\u65e9\u8d77\u304d\u304c\u5f97\u610f\u304b\u3001\u591c\u578b\u304b\u3092\u6c7a\u5b9a\u3002<\/li>\n\n\n\n<li><strong>ADRB1\u907a\u4f1d\u5b50\uff08\u4ea4\u611f\u795e\u7d4c\u6d3b\u52d5\uff09<\/strong> \u2192 \u30b9\u30c8\u30ec\u30b9\u306b\u3088\u308b\u7761\u7720\u306e\u8cea\u306e\u5909\u5316\u3092\u5236\u5fa1\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u5411\u3051\u306e\u7761\u7720\u6700\u9069\u5316<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PER3\u9577\u9396\u578b\uff08\u671d\u578b\uff09<\/strong> \u2192 \u671d\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u52b9\u679c\u7684\u3067\u3001\u591c\u9593\u306e\u7761\u7720\u3092\u6700\u9069\u5316\u3002<\/li>\n\n\n\n<li><strong>ADRB1\u5909\u7570\u578b\uff08\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u304c\u4f4e\u3044\uff09<\/strong> \u2192 \u591c\u306e\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6\u3092\u907f\u3051\u3001\u30e1\u30e9\u30c8\u30cb\u30f3\u30b5\u30d7\u30ea\u3092\u6d3b\u7528\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7761\u7720\u6642\u9593\u304c6\u6642\u9593\u672a\u6e80\u306e\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u6301\u4e45\u529b\u306e\u56de\u5fa9\u306b\u60aa\u5f71\u97ff\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff084\uff09AI\u3068\u30b2\u30ce\u30e0\u30c7\u30fc\u30bf\u3092\u6d3b\u7528\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/31058648_m-1024x585.jpg\" alt=\"\u30d3\u30b8\u30cd\u30b9\u30ec\u30dd\u30fc\u30c8\u304c\u8868\u793a\u3055\u308c\u305f\u30e2\u30cb\u30bf\u30fc\" class=\"wp-image-6110\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31058648_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31058648_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31058648_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31058648_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31058648_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8fd1\u5e74\u3001AI\u6280\u8853\u304c\u767a\u5c55\u3057\u3001<strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3068\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u306e\u751f\u4f53\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u3057\u3066\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u6700\u9069\u5316\u3059\u308b\u30b7\u30b9\u30c6\u30e0<\/strong>\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>AI\u6d3b\u7528\u306e\u30dd\u30a4\u30f3\u30c8<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30a6\u30a7\u30a2\u30e9\u30d6\u30eb\u30c7\u30d0\u30a4\u30b9\u3068\u9023\u643a\u3057\u3001\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u8ca0\u8377\u3092\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u5206\u6790\u3002<\/strong><\/li>\n\n\n\n<li><strong>\u5fc3\u62cd\u5909\u52d5\uff08HRV\uff09\u30c7\u30fc\u30bf\u3068\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u7d71\u5408\u3057\u3001\u75b2\u52b4\u5ea6\u306b\u5fdc\u3058\u305f\u4f11\u606f\u3092\u63d0\u6848\u3002<\/strong><\/li>\n\n\n\n<li><strong>AI\u304c\u904e\u53bb\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30c7\u30fc\u30bf\u3068\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3092\u5206\u6790\u3057\u3001\u6700\u9069\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30e1\u30cb\u30e5\u30fc\u3092\u751f\u6210\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>AI\u3068\u30b2\u30ce\u30e0\u30c7\u30fc\u30bf\u3092\u6d3b\u7528\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u3001\u5f93\u6765\u306e\u4e00\u822c\u7684\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3088\u308a\u3082\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-f5a72f80-7fff-9446-1829-d0a11eac6d21\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p><strong>\u307e\u3068\u3081<\/strong><\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u6301\u4e45\u529b\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u500b\u5225\u5316\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u6700\u9069\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3001\u6804\u990a\u7ba1\u7406\u3001\u30ea\u30ab\u30d0\u30ea\u30fc\u6226\u7565\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3055\u3089\u306b\u3001AI\u6280\u8853\u3084\u30a6\u30a7\u30a2\u30e9\u30d6\u30eb\u30c7\u30d0\u30a4\u30b9\u3068\u306e\u9023\u643a\u306b\u3088\u308a\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6700\u9069\u5316\u3082\u9032\u5316\u3057\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u89e3\u6790\u3092\u6d3b\u7528\u3057\u3001\u79d1\u5b66\u7684\u6839\u62e0\u306b\u57fa\u3065\u3044\u305f\u6301\u4e45\u529b\u5411\u4e0a\u3092\u76ee\u6307\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u7c21\u5358\u30fb\u5b89\u5fc3\uff01<br \/><span>\u8ff7\u308f\u305a\u59cb\u3081\u308b\u305f\u3081\u306b<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u306f\u3058\u3081\u306b \u30b9\u30dd\u30fc\u30c4\u79d1\u5b66\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u6301\u4e45\u529b\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u9023\u6027\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u591a\u578b\u304c\u6301\u4e45\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u6301\u4e45\u529b\u306b\u95a2\u9023\u3059\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50\u3068\u305d\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066\u3001\u6700\u65b0\u306e\u7814 [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":4269,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6,1],"tags":[],"class_list":["post-610","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-basicknowledge","category-latest-technology"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/610","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/comments?post=610"}],"version-history":[{"count":4,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/610\/revisions"}],"predecessor-version":[{"id":6380,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/610\/revisions\/6380"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media\/4269"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media?parent=610"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/categories?post=610"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/tags?post=610"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}