{"id":6135,"date":"2025-02-19T04:23:21","date_gmt":"2025-02-19T04:23:21","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=6135"},"modified":"2025-02-19T04:23:22","modified_gmt":"2025-02-19T04:23:22","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e6%83%85%e5%a0%b1%e3%81%a7%e8%a6%8b%e7%9b%b4%e3%81%99%e3%82%a2%e3%83%ac%e3%83%ab%e3%82%ae%e3%83%bc%e4%bd%93%e8%b3%aa","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e6%83%85%e5%a0%b1%e3%81%a7%e8%a6%8b%e7%9b%b4%e3%81%99%e3%82%a2%e3%83%ac%e3%83%ab%e3%82%ae%e3%83%bc%e4%bd%93%e8%b3%aa\/","title":{"rendered":"\u907a\u4f1d\u5b50\u60c5\u5831\u3067\u898b\u76f4\u3059\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea"},"content":{"rendered":"\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u7684\u8981\u56e0\u304c\u8907\u96d1\u306b\u7d61\u307f\u5408\u3063\u3066\u767a\u75c7\u3057\u307e\u3059\u3002\u8fd1\u5e74\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306b\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u57fa\u3065\u304f\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306e\u7406\u89e3\u3068\u3001\u305d\u306e\u5fdc\u7528\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306f\u3001\u514d\u75ab\u7cfb\u306e\u904e\u5270\u53cd\u5fdc\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u307e\u3059\u3002\u3053\u306e\u904e\u5270\u53cd\u5fdc\u306b\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u5927\u304d\u304f\u5f71\u97ff\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u7406\u5316\u5b66\u7814\u7a76\u6240\u306e\u7814\u7a76\u3067\u306f\u3001\u8ee2\u5199\u56e0\u5b50\u300cMina\u300d\u306e\u907a\u4f1d\u5b50\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306e\u30de\u30a6\u30b9\u3067\u306f\u3001Mina\u306e\u767a\u73fe\u91cf\u304c\u5c11\u306a\u304f\u3001\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3-4\uff08IL-4\uff09\u306e\u7523\u751f\u304c\u6291\u5236\u3055\u308c\u306a\u3044\u305f\u3081\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u3092\u767a\u75c7\u3057\u3084\u3059\u3044\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/www.riken.jp\/press\/2009\/20090724\/index.html?utm_source=chatgpt.com\">riken.jp<\/a><\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u6771\u5317\u5927\u5b66\u306e\u7814\u7a76\u3067\u306f\u3001\u7d041\u4e07\u4eba\u3092\u5bfe\u8c61\u306b\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u89e3\u6790\uff08GWAS\uff09\u3092\u884c\u3044\u3001IgE\u6297\u4f53\u6fc3\u5ea6\u3068\u95a2\u9023\u3059\u308b\u65b0\u305f\u306a\u907a\u4f1d\u5b50\u5909\u7570\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002\u7279\u306b\u3001IL-4\u53d7\u5bb9\u4f53\u03b1\u9396\u907a\u4f1d\u5b50\u4e0a\u306e\u4e00\u5869\u57fa\u591a\u578b\uff08SNP\uff09\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/www.tohoku.ac.jp\/japanese\/2021\/05\/press20210526-02-allergies.html?utm_source=chatgpt.com\">tohoku.ac.jp<\/a><\/p>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306e\u8a55\u4fa1<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u4eba\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u3092\u8a73\u7d30\u306b\u8a55\u4fa1\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u306e\u6709\u7121\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u3069\u306e\u3088\u3046\u306a\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306b\u304b\u304b\u308a\u3084\u3059\u3044\u304b\u3001\u307e\u305f\u306f\u91cd\u75c7\u5316\u3057\u3084\u3059\u3044\u304b\u3092\u4e88\u6e2c\u3067\u304d\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u65e9\u671f\u306e\u4e88\u9632\u7b56\u3084\u9069\u5207\u306a\u6cbb\u7642\u6cd5\u306e\u9078\u629e\u304c\u53ef\u80fd\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u57fa\u3065\u304f\u500b\u5225\u5316\u533b\u7642\u306e\u53ef\u80fd\u6027<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u57fa\u306b\u3057\u305f\u500b\u5225\u5316\u533b\u7642\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306e\u6cbb\u7642\u306b\u65b0\u305f\u306a\u53ef\u80fd\u6027\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002\u60a3\u8005\u4e00\u4eba\u3072\u3068\u308a\u306e\u907a\u4f1d\u7684\u80cc\u666f\u306b\u5408\u308f\u305b\u3066\u3001\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u3084\u85ac\u5264\u3092\u9078\u629e\u3059\u308b\u3053\u3068\u3067\u3001\u6cbb\u7642\u52b9\u679c\u306e\u5411\u4e0a\u3084\u526f\u4f5c\u7528\u306e\u8efd\u6e1b\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001IL-4\u53d7\u5bb9\u4f53\u03b1\u9396\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u60a3\u8005\u306b\u306f\u3001IL-4\u3084IL-13\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u963b\u5bb3\u3059\u308b\u85ac\u5264\u304c\u6709\u52b9\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/www.tohoku.ac.jp\/japanese\/2021\/05\/press20210526-02-allergies.html?utm_source=chatgpt.com\">tohoku.ac.jp<\/a><\/p>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3068\u306e\u95a2\u9023\u6027<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u3068\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u306f\u3001\u4e00\u898b\u7570\u306a\u308b\u75be\u60a3\u7fa4\u306e\u3088\u3046\u306b\u601d\u308f\u308c\u307e\u3059\u304c\u3001\u5171\u901a\u306e\u907a\u4f1d\u7684\u7279\u5fb4\u3092\u6301\u3064\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u5927\u962a\u5927\u5b66\u306e\u7814\u7a76\u3067\u306f\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u3092\u5bfe\u8c61\u306b\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u89e3\u6790\u3092\u884c\u3044\u3001\u4e21\u8005\u306b\u5171\u901a\u3059\u308b\u907a\u4f1d\u5b50\u591a\u578b\u3092\u7279\u5b9a\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u8907\u6570\u306e\u75be\u60a3\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u305f\u65b0\u305f\u306a\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><a href=\"https:\/\/resou.osaka-u.ac.jp\/ja\/research\/2022\/20220627_1?utm_source=chatgpt.com\">resou.osaka-u.ac.jp<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u7a2e\u985e\u3068\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u306f\u3055\u307e\u3056\u307e\u306a\u7a2e\u985e\u304c\u3042\u308a\u3001\u305d\u308c\u305e\u308c\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u304c\u7570\u306a\u308a\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u4ee3\u8868\u7684\u306a\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u3068\u305d\u306e\u907a\u4f1d\u7684\u80cc\u666f\u3092\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/29370504_m-1024x683.jpg\" alt=\"\u30cf\u30f3\u30d0\u30fc\u30b0\u3092\u98df\u3079\u308b\u5973\u6027\u306e\u53e3\u5143\" class=\"wp-image-6143\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/29370504_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/29370504_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/29370504_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/29370504_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/29370504_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306f\u3001\u7279\u5b9a\u306e\u98df\u54c1\u306b\u5bfe\u3057\u3066\u514d\u75ab\u7cfb\u304c\u904e\u5270\u53cd\u5fdc\u3092\u8d77\u3053\u3059\u3053\u3068\u3067\u767a\u75c7\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA\u907a\u4f1d\u5b50<\/strong>\uff1a\u514d\u75ab\u5fdc\u7b54\u3092\u8abf\u6574\u3057\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u306b\u5f71\u97ff\u3002<\/li>\n\n\n\n<li><strong>SPINK5\u907a\u4f1d\u5b50<\/strong>\uff1a\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u8abf\u7bc0\u3057\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3002<\/li>\n\n\n\n<li><strong>IL-4R\u907a\u4f1d\u5b50<\/strong>\uff1a\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3-4\u306e\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3057\u3001\u514d\u75ab\u53cd\u5fdc\u3092\u5f37\u5316\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b\u30ea\u30b9\u30af\u8a55\u4fa1<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA-DQ2\/DQ8\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong>\u306f\u3001\u5c0f\u9ea6\u3084\u4e73\u88fd\u54c1\u306b\u5bfe\u3059\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u3092\u767a\u75c7\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>SPINK5\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u4eba<\/strong>\u306f\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u307b\u304b\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u30ea\u30b9\u30af\u3082\u9ad8\u307e\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>SPINK5\u907a\u4f1d\u5b50\u5909\u7570\u304c\u3042\u308b\u4eba\u306f\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u3068\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3092\u4f75\u767a\u3057\u3084\u3059\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u82b1\u7c89\u75c7\uff08\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\uff09\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u82b1\u7c89\u75c7\u306f\u3001\u74b0\u5883\u8981\u56e0\u3068\u907a\u4f1d\u7684\u8981\u56e0\u304c\u7d44\u307f\u5408\u308f\u3055\u3063\u3066\u767a\u75c7\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA-DRB1\u907a\u4f1d\u5b50<\/strong>\uff1a\u6297\u539f\u63d0\u793a\u306e\u5f79\u5272\u3092\u6301\u3061\u3001\u82b1\u7c89\u306b\u5bfe\u3059\u308b\u514d\u75ab\u53cd\u5fdc\u3092\u8abf\u6574\u3002<\/li>\n\n\n\n<li><strong>IL-13\u907a\u4f1d\u5b50<\/strong>\uff1a\u514d\u75ab\u7d30\u80de\u306e\u708e\u75c7\u53cd\u5fdc\u3092\u4fc3\u9032\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b\u30ea\u30b9\u30af\u8a55\u4fa1<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA-DRB1\u306e\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong>\u306f\u3001\u30b9\u30ae\u82b1\u7c89\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>IL-13\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong>\u306f\u3001\u82b1\u7c89\u75c7\u306e\u75c7\u72b6\u304c\u91cd\u304f\u306a\u308a\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>IL-13\u907a\u4f1d\u5b50\u5909\u7570\u304c\u82b1\u7c89\u75c7\u306e\u91cd\u75c7\u5316\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306f\u3001\u76ae\u819a\u30d0\u30ea\u30a2\u306e\u7570\u5e38\u3068\u514d\u75ab\u904e\u5270\u53cd\u5fdc\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FLG\uff08\u30d5\u30a3\u30e9\u30b0\u30ea\u30f3\uff09\u907a\u4f1d\u5b50<\/strong>\uff1a\u76ae\u819a\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u7dad\u6301\u3057\u3001\u5916\u90e8\u523a\u6fc0\u304b\u3089\u808c\u3092\u5b88\u308b\u3002<\/li>\n\n\n\n<li><strong>TSLP\u907a\u4f1d\u5b50<\/strong>\uff1a\u708e\u75c7\u3092\u8a98\u5c0e\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u4fc3\u9032\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b\u30ea\u30b9\u30af\u8a55\u4fa1<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FLG\u306e\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong>\u306f\u3001\u76ae\u819a\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3092\u767a\u75c7\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>TSLP\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong>\u306f\u3001\u76ae\u819a\u708e\u306e\u708e\u75c7\u304c\u60aa\u5316\u3057\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FLG\u907a\u4f1d\u5b50\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3060\u3051\u3067\u306a\u304f\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u30ea\u30b9\u30af\u3082\u9ad8\u307e\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u907a\u4f1d\u5b50\u60c5\u5831\u306b\u57fa\u3065\u304f\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u7b56<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/31796791_m-1024x683.jpg\" alt=\"\u304a\u3044\u3057\u3044\u3055\u3093\u307e\u306e\u671d\u98df\" class=\"wp-image-4916\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31796791_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31796791_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31796791_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31796791_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31796791_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u4e88\u9632\u7b56\u3092\u3088\u308a\u52b9\u679c\u7684\u306b\u7acb\u3066\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u98df\u4e8b\u306b\u3088\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u306b\u57fa\u3065\u304f\u6804\u990a\u7ba1\u7406<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong> \u2192 \u514d\u75ab\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u308b\u305f\u3081\u306b\u3001\u767a\u9175\u98df\u54c1\uff08\u30e8\u30fc\u30b0\u30eb\u30c8\u3001\u7d0d\u8c46\uff09\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3002<\/li>\n\n\n\n<li><strong>FLG\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong> \u2192 \u76ae\u819a\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u9ad8\u3081\u308b\u305f\u3081\u306b\u3001\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3092\u542b\u3080\u98df\u54c1\uff08\u9752\u9b5a\u3001\u4e9c\u9ebb\u4ec1\u6cb9\uff09\u3092\u6442\u53d6\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3059\u308b\u6804\u990a\u7d20<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff08\u4e73\u9178\u83cc\u30fb\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\uff09<\/strong>\uff1a\u8178\u5185\u74b0\u5883\u3092\u6574\u3048\u3001\u514d\u75ab\u5fdc\u7b54\u3092\u8abf\u6574\u3002<\/li>\n\n\n\n<li><strong>\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\uff08\u7dd1\u8336\u30fb\u8d64\u30ef\u30a4\u30f3\uff09<\/strong>\uff1a\u6297\u708e\u75c7\u4f5c\u7528\u3092\u6301\u3061\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u7387\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/jamanetwork.com\/\">jamanetwork.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u74b0\u5883\u8981\u56e0\u306e\u7ba1\u7406<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u74b0\u5883\u5bfe\u7b56<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA-DRB1\u306e\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong> \u2192 \u82b1\u7c89\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u305f\u3081\u3001\u7a7a\u6c17\u6e05\u6d44\u6a5f\u3084\u82b1\u7c89\u30d5\u30a3\u30eb\u30bf\u30fc\u3092\u6d3b\u7528\u3002<\/li>\n\n\n\n<li><strong>TSLP\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u4eba<\/strong> \u2192 \u76ae\u819a\u708e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u305f\u3081\u3001\u4f4e\u523a\u6fc0\u306e\u30b9\u30ad\u30f3\u30b1\u30a2\u88fd\u54c1\u3092\u9078\u629e\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u5177\u4f53\u7684\u306a\u74b0\u5883\u7ba1\u7406\u7b56<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5ba4\u5185\u306e\u6e7f\u5ea6\u309250\uff5e60%\u306b\u4fdd\u3061\u3001\u30c0\u30cb\u30fb\u30ab\u30d3\u306e\u7e41\u6b96\u3092\u9632\u3050\u3002<\/strong><\/li>\n\n\n\n<li><strong>\u82b1\u7c89\u75c7\u5bfe\u7b56\u3068\u3057\u3066\u3001\u5e30\u5b85\u5f8c\u3059\u3050\u306b\u8863\u670d\u3092\u7740\u66ff\u3048\u3001\u6d17\u9854\u3092\u884c\u3046\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5ba4\u5185\u74b0\u5883\u3092\u9069\u5207\u306b\u7ba1\u7406\u3059\u308b\u3053\u3068\u3067\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u306e\u6539\u5584\u304c\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u533b\u7642<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u3082\u500b\u5225\u5316\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u500b\u5225\u5316\u6cbb\u7642\u306e\u4f8b<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>IL-4R\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong> \u2192 <strong>IL-4\u3084IL-13\u3092\u963b\u5bb3\u3059\u308b\u751f\u7269\u5b66\u7684\u88fd\u5264\uff08\u30c7\u30e5\u30d4\u30eb\u30de\u30d6\uff09\u304c\u6709\u52b9<\/strong>\u3002<\/li>\n\n\n\n<li><strong>TSLP\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u4eba<\/strong> \u2192 <strong>\u6297\u708e\u75c7\u4f5c\u7528\u306e\u3042\u308b\u30b9\u30c6\u30ed\u30a4\u30c9\u5916\u7528\u85ac\u306e\u4f7f\u7528\u304c\u63a8\u5968\u3055\u308c\u308b<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u5b9f\u7528\u5316\u306e\u9032\u5c55<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u7814\u7a76\u304c\u9032\u884c\u4e2d\u3002<\/strong><\/li>\n\n\n\n<li><strong>\u500b\u5225\u5316\u6cbb\u7642\u306b\u3088\u3063\u3066\u3001\u5f93\u6765\u306e\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u304c\u52b9\u304d\u306b\u304f\u3044\u4eba\u306b\u3082\u52b9\u679c\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u53ef\u80fd\u306b\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u6cbb\u7642\u304c\u3001\u5f93\u6765\u306e\u753b\u4e00\u7684\u306a\u6cbb\u7642\u3088\u308a\u3082\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u6700\u65b0\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/31878770_m-1024x768.jpg\" alt=\"\u305f\u304f\u3055\u3093\u306e\u85ac\u3092\u4e21\u624b\u3067\u6301\u3064\" class=\"wp-image-4596\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31878770_m-1024x768.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31878770_m-300x225.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31878770_m-768x576.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31878770_m-1536x1152.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31878770_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u57fa\u306b\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u304c\u6025\u901f\u306b\u9032\u6b69\u3057\u3066\u3044\u307e\u3059\u3002\u5f93\u6765\u306e\u6cbb\u7642\u6cd5\u3068\u306f\u7570\u306a\u308a\u3001\u500b\u3005\u306e\u907a\u4f1d\u7684\u7279\u5fb4\u3092\u8003\u616e\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u3067\u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u6cbb\u7642\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u30d0\u30a4\u30aa\u533b\u85ac\u54c1\u306b\u3088\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<p>\u5f93\u6765\u306e\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u3084\u30b9\u30c6\u30ed\u30a4\u30c9\u6cbb\u7642\u306b\u52a0\u3048\u3066\u3001<strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30d0\u30a4\u30aa\u533b\u85ac\u54c1<\/strong>\u304c\u767b\u5834\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3084\u6c17\u7ba1\u652f\u5598\u606f\u306e\u6cbb\u7642\u306b\u306f\u3001\u751f\u7269\u5b66\u7684\u88fd\u5264\u304c\u6709\u52b9\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u4ee3\u8868\u7684\u306a\u30d0\u30a4\u30aa\u533b\u85ac\u54c1<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c7\u30e5\u30d4\u30eb\u30de\u30d6\uff08Dupilumab\uff09<\/strong>\uff1aIL-4\u304a\u3088\u3073IL-13\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u963b\u5bb3\u3057\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3084\u5598\u606f\u3092\u6539\u5584\u3002<\/li>\n\n\n\n<li><strong>\u30aa\u30de\u30ea\u30ba\u30de\u30d6\uff08Omalizumab\uff09<\/strong>\uff1aIgE\u6297\u4f53\u3092\u6a19\u7684\u3068\u3057\u3001\u91cd\u5ea6\u306e\u5598\u606f\u3084\u6162\u6027\u8541\u9ebb\u75b9\u3092\u6cbb\u7642\u3002<\/li>\n\n\n\n<li><strong>\u30e1\u30dd\u30ea\u30ba\u30de\u30d6\uff08Mepolizumab\uff09<\/strong>\uff1aIL-5\u3092\u6291\u5236\u3057\u3001\u597d\u9178\u7403\u6027\u5598\u606f\u306e\u75c7\u72b6\u3092\u8efd\u6e1b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u57fa\u3065\u304f\u9069\u5fdc<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>IL-4R\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u30c7\u30e5\u30d4\u30eb\u30de\u30d6\u306e\u52b9\u679c\u304c\u9ad8\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>IgE\u5024\u304c\u9ad8\u3044\u907a\u4f1d\u7684\u80cc\u666f\u3092\u6301\u3064\u4eba\u306f\u3001\u30aa\u30de\u30ea\u30ba\u30de\u30d6\u306b\u3088\u308b\u6cbb\u7642\u304c\u6709\u52b9\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>IL-4R\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u60a3\u8005\u306b\u30c7\u30e5\u30d4\u30eb\u30de\u30d6\u3092\u6295\u4e0e\u3057\u305f\u7d50\u679c\u3001\u76ae\u819a\u306e\u708e\u75c7\u304c\u6709\u610f\u306b\u6539\u5584\u3057\u305f\u3053\u3068\u304c\u793a\u3055\u308c\u305f<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/jamanetwork.com\/\">jamanetwork.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\uff08CRISPR\uff09\u3092\u7528\u3044\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u306e\u53ef\u80fd\u6027<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u300cCRISPR-Cas9\u300d\u3092\u6d3b\u7528\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306e\u6839\u672c\u7684\u306a\u6cbb\u7642\u3092\u76ee\u6307\u3059\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>CRISPR\u6280\u8853\u306b\u3088\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u306e\u30a2\u30d7\u30ed\u30fc\u30c1<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u4fee\u6b63<\/strong>\u3057\u3001\u904e\u5270\u306a\u514d\u75ab\u53cd\u5fdc\u3092\u6291\u5236\u3002<\/li>\n\n\n\n<li><strong>IL-4\u3084IL-13\u306e\u904e\u5270\u767a\u73fe\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u708e\u75c7\u53cd\u5fdc\u3092\u8efd\u6e1b\u3002<\/strong><\/li>\n\n\n\n<li><strong>Treg\uff08\u5236\u5fa1\u6027T\u7d30\u80de\uff09\u3092\u5897\u3084\u3059\u907a\u4f1d\u5b50\u64cd\u4f5c\u3092\u884c\u3044\u3001\u514d\u75ab\u5bdb\u5bb9\u3092\u4fc3\u9032\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u306e\u9032\u5c55<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30cf\u30fc\u30d0\u30fc\u30c9\u5927\u5b66\u306e\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001<strong>\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u5b9f\u9a13\u3067\u3001CRISPR\u6280\u8853\u306b\u3088\u308a\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u5598\u606f\u3092\u6839\u672c\u7684\u306b\u6291\u5236\u3067\u304d\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u305f<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u306e\u305f\u3081\u306e\u30ef\u30af\u30c1\u30f3\u958b\u767a<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/31038988_m-1024x585.jpg\" alt=\"\u30ef\u30af\u30c1\u30f3\u6ce8\u5c04\" class=\"wp-image-6150\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31038988_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31038988_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31038988_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31038988_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31038988_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30ef\u30af\u30c1\u30f3\u6280\u8853\u3092\u5fdc\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u3082\u9032\u3093\u3067\u304a\u308a\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u5225\u306b\u6700\u9069\u5316\u3055\u308c\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u30ef\u30af\u30c1\u30f3\u306e\u958b\u767a\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u4ee3\u8868\u7684\u306a\u30a2\u30ec\u30eb\u30ae\u30fc\u30ef\u30af\u30c1\u30f3<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u820c\u4e0b\u514d\u75ab\u7642\u6cd5\uff08SLIT\uff09<\/strong>\uff1a\u30a2\u30ec\u30eb\u30b2\u30f3\u30a8\u30ad\u30b9\u3092\u820c\u4e0b\u3067\u5438\u53ce\u3055\u305b\u3001\u514d\u75ab\u7cfb\u3092\u9806\u5fdc\u3055\u305b\u308b\u3002<\/li>\n\n\n\n<li><strong>DNA\u30ef\u30af\u30c1\u30f3<\/strong>\uff1a\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u6291\u3048\u308b\u907a\u4f1d\u5b50\u3092\u6295\u4e0e\u3057\u3001\u514d\u75ab\u7cfb\u3092\u518d\u30d7\u30ed\u30b0\u30e9\u30e0\u5316\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u57fa\u3065\u304f\u500b\u5225\u5316<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA\u907a\u4f1d\u5b50\u306e\u578b\u306b\u5fdc\u3058\u3066\u3001\u6700\u9069\u306a\u514d\u75ab\u7642\u6cd5\u306e\u9078\u629e\u304c\u53ef\u80fd\u306b\u306a\u308b\u3002<\/strong><\/li>\n\n\n\n<li><strong>IL-10\u306e\u767a\u73fe\u91cf\u304c\u591a\u3044\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u514d\u75ab\u7642\u6cd5\u306e\u52b9\u679c\u304c\u9ad8\u3044\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u820c\u4e0b\u514d\u75ab\u7642\u6cd5\u304cHLA-DQ2\u5909\u7570\u3092\u6301\u3064\u82b1\u7c89\u75c7\u60a3\u8005\u306b\u5bfe\u3057\u3066\u7279\u306b\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff084\uff09\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u8178\u5185\u30d5\u30ed\u30fc\u30e9\uff08\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\uff09\u304c\u514d\u75ab\u7cfb\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u304c\u6ce8\u76ee\u3055\u308c\u3066\u304a\u308a\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u500b\u3005\u306e\u8178\u5185\u74b0\u5883\u306b\u5408\u308f\u305b\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u304c\u53ef\u80fd<\/strong>\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FUT2\u907a\u4f1d\u5b50<\/strong>\uff1a\u8178\u5185\u7d30\u83cc\u306e\u69cb\u6210\u3092\u6c7a\u5b9a\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<\/li>\n\n\n\n<li><strong>NOD2\u907a\u4f1d\u5b50<\/strong>\uff1a\u8178\u7ba1\u514d\u75ab\u3092\u8abf\u6574\u3057\u3001\u708e\u75c7\u53cd\u5fdc\u3092\u6291\u5236\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u57fa\u3065\u304f\u8178\u5185\u74b0\u5883\u306e\u6700\u9069\u5316<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FUT2\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u8178\u5185\u7d30\u83cc\u306e\u591a\u69d8\u6027\u304c\u4f4e\u3044\u305f\u3081\u3001\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff08\u4e73\u9178\u83cc\u30fb\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\uff09\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u308b\u3002<\/strong><\/li>\n\n\n\n<li><strong>NOD2\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u304c\u4f4e\u3044\u4eba\u306f\u3001\u30d7\u30ec\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff08\u30aa\u30fc\u30c8\u30df\u30fc\u30eb\u3001\u30d0\u30ca\u30ca\uff09\u3092\u591a\u304f\u6442\u308b\u3053\u3068\u3067\u514d\u75ab\u30d0\u30e9\u30f3\u30b9\u3092\u6539\u5584\u3067\u304d\u308b\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FUT2\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u8178\u5185\u30d5\u30ed\u30fc\u30e9\u3092\u6574\u3048\u308b\u3053\u3068\u3067\u30a2\u30ec\u30eb\u30ae\u30fc\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff085\uff09\u672a\u6765\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u7ba1\u7406\uff1aAI\u3068\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u878d\u5408<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/26959730_m-1024x683.jpg\" alt=\"\u8cc7\u6599\u30fb\u30c7\u30a3\u30b9\u30d7\u30ec\u30a4\" class=\"wp-image-6157\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/26959730_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/26959730_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/26959730_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/26959730_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/26959730_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>AI\u6280\u8853\u306e\u9032\u5316\u306b\u3088\u308a\u3001<strong>\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3068\u751f\u6d3b\u7fd2\u6163\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u6e2c\u30b7\u30b9\u30c6\u30e0<\/strong>\u306e\u958b\u767a\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>AI\u3092\u6d3b\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u7ba1\u7406\u306e\u7279\u5fb4<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3092\u89e3\u6790\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7\u30ea\u30b9\u30af\u3092\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u4e88\u6e2c\u3002<\/strong><\/li>\n\n\n\n<li><strong>\u98df\u4e8b\u30fb\u904b\u52d5\u30fb\u30b9\u30c8\u30ec\u30b9\u30ec\u30d9\u30eb\u3092\u8003\u616e\u3057\u3001\u6700\u9069\u306a\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u30d7\u30e9\u30f3\u3092\u81ea\u52d5\u63d0\u6848\u3002<\/strong><\/li>\n\n\n\n<li><strong>\u75c7\u72b6\u306e\u5909\u5316\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3057\u3001\u533b\u7642\u6a5f\u95a2\u3078\u306e\u76f8\u8ac7\u30bf\u30a4\u30df\u30f3\u30b0\u3092\u901a\u77e5\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u306e\u9032\u5c55<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Google\u306e\u30d8\u30eb\u30b9\u30b1\u30a2\u90e8\u9580\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3068AI\u3092\u6d3b\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u8a3a\u65ad\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a\u3092\u9032\u3081\u3066\u3044\u308b\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u8a3a\u65ad\u306e\u9032\u5316<\/strong><\/h2>\n\n\n\n<p>\u5f93\u6765\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u8a3a\u65ad\u306f\u3001\u76ae\u819a\u30c6\u30b9\u30c8\u3084\u8840\u6db2\u691c\u67fb\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u6b63\u78ba\u3067\u500b\u5225\u5316\u3055\u308c\u305f\u8a3a\u65ad\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u8a3a\u65ad\u306e\u9032\u5316\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u8a3a\u65ad\u306e\u30e1\u30ea\u30c3\u30c8<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u30e1\u30ea\u30c3\u30c8\u304c\u5f97\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>1. \u767a\u75c7\u30ea\u30b9\u30af\u306e\u65e9\u671f\u8a55\u4fa1<\/strong><\/h4>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u884c\u3046\u3053\u3068\u3067\u3001<strong>\u75c7\u72b6\u304c\u51fa\u308b\u524d\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u30ea\u30b9\u30af\u3092\u8a55\u4fa1\u3057\u3001\u4e88\u9632\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u53ef\u80fd<\/strong>\u306b\u306a\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>HLA\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u4eba\u306f\u82b1\u7c89\u75c7\u3084\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u305f\u3081\u3001\u65e9\u671f\u304b\u3089\u306e\u74b0\u5883\u7ba1\u7406\u304c\u6709\u52b9<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>2. \u30a2\u30ec\u30eb\u30b2\u30f3\u306e\u7279\u5b9a<\/strong><\/h4>\n\n\n\n<p>\u5f93\u6765\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u691c\u67fb\u3067\u306f\u3001\u65e2\u5b58\u306e\u30a2\u30ec\u30eb\u30b2\u30f3\u306b\u5bfe\u3059\u308b\u6297\u4f53\u306e\u6709\u7121\u3092\u78ba\u8a8d\u3059\u308b\u65b9\u6cd5\u304c\u4e00\u822c\u7684\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u6f5c\u5728\u7684\u306a\u30a2\u30ec\u30eb\u30b2\u30f3\u3092\u3088\u308a\u8a73\u7d30\u306b\u7279\u5b9a<\/strong>\u3057\u3001\u672a\u767a\u75c7\u306e\u6bb5\u968e\u3067\u3082\u30ea\u30b9\u30af\u8a55\u4fa1\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>3. \u500b\u5225\u5316\u533b\u7642\u306e\u5b9f\u73fe<\/strong><\/h4>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u57fa\u306b\u3001<strong>\u500b\u3005\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306b\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u3092\u9078\u629e\u3067\u304d\u308b<\/strong>\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>IL-4R\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u60a3\u8005\u306b\u306f\u30c7\u30e5\u30d4\u30eb\u30de\u30d6\u304c\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059<\/strong>\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u6700\u65b0\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u6280\u8853<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/2049057_m-1-1024x683.jpg\" alt=\"\" class=\"wp-image-5945\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2049057_m-1-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2049057_m-1-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2049057_m-1-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2049057_m-1-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2049057_m-1.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8fd1\u5e74\u3001\u6b21\u4e16\u4ee3\u30b7\u30fc\u30af\u30a8\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\u6280\u8853\u306e\u9032\u5316\u306b\u3088\u308a\u3001<strong>\u4f4e\u30b3\u30b9\u30c8\u3067\u9ad8\u7cbe\u5ea6\u306a\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u53ef\u80fd<\/strong>\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>1. \u30de\u30eb\u30c1\u30aa\u30df\u30af\u30b9\u89e3\u6790<\/strong><\/h4>\n\n\n\n<p>\u30de\u30eb\u30c1\u30aa\u30df\u30af\u30b9\u89e3\u6790\u3068\u306f\u3001<strong>\u30b2\u30ce\u30e0\uff08DNA\uff09\u3001\u30c8\u30e9\u30f3\u30b9\u30af\u30ea\u30d7\u30c8\u30fc\u30e0\uff08RNA\uff09\u3001\u30d7\u30ed\u30c6\u30aa\u30fc\u30e0\uff08\u30bf\u30f3\u30d1\u30af\u8cea\uff09\u306a\u3069\u306e\u591a\u5c64\u7684\u306a\u60c5\u5831\u3092\u7d71\u5408\u89e3\u6790\u3059\u308b\u624b\u6cd5<\/strong>\u3067\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001<strong>\u907a\u4f1d\u5b50\u5909\u7570\u3060\u3051\u3067\u306a\u304f\u3001\u5b9f\u969b\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u30ec\u30d9\u30eb\u306e\u5909\u5316\u307e\u3067\u8a73\u7d30\u306b\u89e3\u6790<\/strong>\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>2. AI\u3092\u6d3b\u7528\u3057\u305f\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u89e3\u6790<\/strong><\/h4>\n\n\n\n<p>AI\uff08\u4eba\u5de5\u77e5\u80fd\uff09\u306e\u9032\u5316\u306b\u3088\u308a\u3001<strong>\u81a8\u5927\u306a\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3092\u9ad8\u901f\u304b\u3064\u6b63\u78ba\u306b\u89e3\u6790\u3059\u308b\u6280\u8853\u304c\u767a\u5c55<\/strong>\u3057\u3066\u3044\u307e\u3059\u3002AI\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u500b\u3005\u306e\u60a3\u8005\u306b\u6700\u9069\u306a\u4e88\u9632\u7b56\u3084\u6cbb\u7642\u6cd5\u3092\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u63d0\u6848\u3067\u304d\u308b\u30b7\u30b9\u30c6\u30e0\u304c\u958b\u767a\u4e2d<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NGS\u6280\u8853\u3092\u6d3b\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u8a3a\u65ad\u306e\u7cbe\u5ea6\u304c\u5f93\u6765\u306e\u8840\u6db2\u691c\u67fb\u3088\u308a\u3082\u9ad8\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.nature.com\/\">nature.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u306e\u672a\u6765<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u57fa\u306b\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u306f\u3001\u4eca\u5f8c\u3055\u3089\u306b\u9032\u5316\u3057\u3001\u3088\u308a\u7cbe\u5bc6\u3067\u52b9\u679c\u7684\u306a\u6cbb\u7642\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u907a\u4f1d\u5b50\u6cbb\u7642\u306b\u3088\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u6839\u6cbb\u306e\u53ef\u80fd\u6027<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\uff08CRISPR-Cas9\uff09\u3092\u7528\u3044\u3066\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u6839\u672c\u7684\u306a\u539f\u56e0\u3068\u306a\u308b\u907a\u4f1d\u5b50\u5909\u7570\u3092\u4fee\u6b63\u3059\u308b\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>CRISPR\u3092\u6d3b\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u306e\u30a2\u30d7\u30ed\u30fc\u30c1<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>IgE\u6297\u4f53\u3092\u904e\u5270\u306b\u7523\u751f\u3059\u308b\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u3092\u6291\u5236<\/strong>\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u8efd\u6e1b\u3002<\/li>\n\n\n\n<li><strong>\u514d\u75ab\u7cfb\u306e\u904e\u5270\u53cd\u5fdc\u3092\u6291\u3048\u308b\u907a\u4f1d\u5b50\uff08FOXP3\uff09\u306e\u767a\u73fe\u3092\u5897\u5f37<\/strong>\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u8010\u6027\u3092\u5411\u4e0a\u3002<\/li>\n\n\n\n<li><strong>\u76ae\u819a\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u6539\u5584\u3059\u308bFLG\u907a\u4f1d\u5b50\u306e\u4fee\u5fa9\u306b\u3088\u308a\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u767a\u75c7\u3092\u9632\u3050\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CRISPR\u6280\u8853\u3092\u7528\u3044\u305f\u30de\u30a6\u30b9\u5b9f\u9a13\u3067\u3001IgE\u6297\u4f53\u306e\u7523\u751f\u3092\u6291\u3048\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u304c\u6539\u5584\u3057\u305f<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u30ca\u30ce\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u3092\u6d3b\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<p>\u30ca\u30ce\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306e\u9032\u5316\u306b\u3088\u308a\u3001<strong>\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u3092\u6291\u5236\u3059\u308b\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u304c\u958b\u767a<\/strong>\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30ca\u30ce\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u3092\u6d3b\u7528\u3057\u305f\u6cbb\u7642\u6cd5<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30ca\u30ce\u7c92\u5b50\u3092\u7528\u3044\u305f\u514d\u75ab\u7642\u6cd5<\/strong>\uff1a\u30a2\u30ec\u30eb\u30b2\u30f3\u3092\u30ca\u30ce\u7c92\u5b50\u306b\u5305\u307f\u8fbc\u3093\u3067\u6295\u4e0e\u3057\u3001\u514d\u75ab\u5bdb\u5bb9\u3092\u8a98\u5c0e\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>\u30bf\u30fc\u30b2\u30c3\u30c8\u30c9\u30e9\u30c3\u30b0\u30c7\u30ea\u30d0\u30ea\u30fc<\/strong>\uff1a\u708e\u75c7\u90e8\u4f4d\u306b\u76f4\u63a5\u85ac\u5264\u3092\u5c4a\u3051\u3001\u526f\u4f5c\u7528\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30ca\u30ce\u7c92\u5b50\u3092\u7528\u3044\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u514d\u75ab\u7642\u6cd5\u306b\u3088\u308a\u3001\u30a2\u30ca\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u306e\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3067\u304d\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/jamanetwork.com\/\">jamanetwork.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u500b\u5225\u5316\u30ef\u30af\u30c1\u30f3\u306e\u958b\u767a<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/31306847_m-1024x768.jpg\" alt=\"\u6ce8\u5c04\" class=\"wp-image-6171\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31306847_m-1024x768.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31306847_m-300x225.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31306847_m-768x576.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31306847_m-1536x1152.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31306847_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f<strong>\u500b\u5225\u5316\u30ef\u30af\u30c1\u30f3<\/strong>\u304c\u958b\u767a\u3055\u308c\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u6839\u672c\u7684\u306a\u4e88\u9632\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u500b\u5225\u5316\u30ef\u30af\u30c1\u30f3\u306e\u7279\u5fb4<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u3066\u6700\u9069\u306a\u30a2\u30ec\u30eb\u30b2\u30f3\u3092\u7279\u5b9a\u3057\u3001\u30ef\u30af\u30c1\u30f3\u3092\u8abf\u6574\u3002<\/strong><\/li>\n\n\n\n<li><strong>AI\u3092\u6d3b\u7528\u3057\u3001\u30ef\u30af\u30c1\u30f3\u306e\u52b9\u679c\u3092\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u89e3\u6790\u3057\u3001\u6700\u9069\u306a\u6295\u4e0e\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u3092\u63d0\u6848\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u30ef\u30af\u30c1\u30f3\u304c\u3001\u5f93\u6765\u306e\u514d\u75ab\u7642\u6cd5\u3088\u308a\u3082\u9ad8\u3044\u6709\u52b9\u6027\u3092\u793a\u3059\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff084\uff09\u672a\u6765\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u7ba1\u7406\u30b7\u30b9\u30c6\u30e0<\/strong><\/h3>\n\n\n\n<p>AI\u3068\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u7d71\u5408\u3057\u3001<strong>\u500b\u5225\u306b\u6700\u9069\u5316\u3055\u308c\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u7ba1\u7406\u30b7\u30b9\u30c6\u30e0<\/strong>\u306e\u958b\u767a\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u6b21\u4e16\u4ee3\u30a2\u30ec\u30eb\u30ae\u30fc\u7ba1\u7406\u306e\u7279\u5fb4<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30b9\u30de\u30fc\u30c8\u30c7\u30d0\u30a4\u30b9\u3068\u9023\u643a\u3057\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u30a2\u30ec\u30eb\u30ae\u30fc\u30ea\u30b9\u30af\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3002<\/strong><\/li>\n\n\n\n<li><strong>\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3068\u74b0\u5883\u8981\u56e0\u3092\u89e3\u6790\u3057\u3001\u767a\u75c7\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u65e5\u3092\u4e88\u6e2c\u3002<\/strong><\/li>\n\n\n\n<li><strong>\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u533b\u7642\u30c7\u30fc\u30bf\u3092\u6d3b\u7528\u3057\u3001\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u3092\u63d0\u6848\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u5b9f\u7528\u5316\u306e\u9032\u5c55<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5927\u624b\u533b\u7642\u6a5f\u95a2\u304cAI\u3068\u907a\u4f1d\u5b50\u89e3\u6790\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a\u3092\u9032\u3081\u3066\u3044\u308b\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. \u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u306e\u65b0\u305f\u306a\u6226\u7565<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306f\u4e00\u5ea6\u767a\u75c7\u3059\u308b\u3068\u9577\u671f\u7684\u306a\u7ba1\u7406\u304c\u5fc5\u8981\u306b\u306a\u308a\u307e\u3059\u304c\u3001<strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u767a\u75c7\u3092\u672a\u7136\u306b\u9632\u3050\u65b0\u305f\u306a\u4e88\u9632\u7b56<\/strong>\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u6700\u65b0\u306e\u7814\u7a76\u3092\u57fa\u306b\u3001\u907a\u4f1d\u5b50\u306b\u57fa\u3065\u3044\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u306e\u65b9\u6cd5\u3092\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff081\uff09\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u6804\u990a\u7642\u6cd5<\/strong><\/h3>\n\n\n\n<p>\u98df\u751f\u6d3b\u306f\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u30ea\u30b9\u30af\u306b\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u9069\u5207\u306a\u6804\u990a\u7ba1\u7406\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u514d\u75ab\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u3068\u6804\u990a\u7d20\u306e\u95a2\u4fc2<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong> \u2192 \u6297\u708e\u75c7\u4f5c\u7528\u306e\u3042\u308b\u98df\u54c1\uff08\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3092\u542b\u3080\u9752\u9b5a\u3001\u30a2\u30dc\u30ab\u30c9\uff09\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u514d\u75ab\u904e\u5270\u53cd\u5fdc\u3092\u6291\u5236\u3002<\/li>\n\n\n\n<li><strong>FLG\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong> \u2192 \u76ae\u819a\u30d0\u30ea\u30a2\u3092\u5f37\u5316\u3059\u308b\u305f\u3081\u306b\u3001\u30bb\u30e9\u30df\u30c9\u3092\u8c4a\u5bcc\u306b\u542b\u3080\u98df\u54c1\uff08\u7384\u7c73\u3001\u5c0f\u9ea6\u80da\u82bd\u3001\u5927\u8c46\uff09\u3092\u6442\u53d6\u3002<\/li>\n\n\n\n<li><strong>IL-10\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 \u6297\u9178\u5316\u4f5c\u7528\u306e\u3042\u308b\u30d3\u30bf\u30df\u30f3C\uff08\u67d1\u6a58\u985e\u3001\u30d4\u30fc\u30de\u30f3\uff09\u3084\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\uff08\u7dd1\u8336\u3001\u30d6\u30eb\u30fc\u30d9\u30ea\u30fc\uff09\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u708e\u75c7\u3092\u6291\u3048\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u306e\u6442\u53d6\u304c\u3001IL-4R\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u30a2\u30ec\u30eb\u30ae\u30fc\u60a3\u8005\u306e\u708e\u75c7\u30ec\u30d9\u30eb\u3092\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-50de066e-7fff-fd1d-b8bf-49e10d51219d\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff082\uff09\u8178\u5185\u30d5\u30ed\u30fc\u30e9\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"769\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/4395676_m-1-1024x769.jpg\" alt=\"\u304a\u306a\u304b\u306b\u624b\u3092\u5f53\u3066\u308b\u5973\u6027\" class=\"wp-image-6007\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4395676_m-1-1024x769.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4395676_m-1-300x225.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4395676_m-1-768x577.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4395676_m-1-1536x1154.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4395676_m-1.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8178\u5185\u74b0\u5883\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u30ea\u30b9\u30af\u306b\u306f\u5bc6\u63a5\u306a\u95a2\u4fc2\u304c\u3042\u308a\u3001\u8178\u5185\u7d30\u83cc\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u308b\u3053\u3068\u304c\u91cd\u8981\u8996\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FUT2\u907a\u4f1d\u5b50<\/strong> \u2192 \u8178\u5185\u7d30\u83cc\u306e\u69cb\u6210\u306b\u5f71\u97ff\u3057\u3001\u5584\u7389\u83cc\u306e\u5b9a\u7740\u3092\u6c7a\u5b9a\u3002<\/li>\n\n\n\n<li><strong>NOD2\u907a\u4f1d\u5b50<\/strong> \u2192 \u8178\u306e\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u3092\u8abf\u7bc0\u3057\u3001\u708e\u75c7\u306e\u767a\u751f\u3092\u9632\u3050\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u8178\u5185\u74b0\u5883\u3092\u6574\u3048\u308b\u65b9\u6cd5<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FUT2\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u4eba<\/strong> \u2192 <strong>\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff08\u4e73\u9178\u83cc\u30fb\u30d3\u30d5\u30a3\u30ba\u30b9\u83cc\uff09\u3092\u591a\u304f\u542b\u3080\u767a\u9175\u98df\u54c1\uff08\u30e8\u30fc\u30b0\u30eb\u30c8\u3001\u30ad\u30e0\u30c1\u3001\u7d0d\u8c46\uff09\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u8178\u5185\u7d30\u83cc\u306e\u591a\u69d8\u6027\u3092\u5897\u3084\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3002<\/strong><\/li>\n\n\n\n<li><strong>NOD2\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 <strong>\u8178\u5185\u306e\u708e\u75c7\u3092\u6291\u3048\u308b\u305f\u3081\u3001\u98df\u7269\u7e4a\u7dad\uff08\u30aa\u30fc\u30c8\u30df\u30fc\u30eb\u3001\u8c46\u985e\uff09\u3084\u30d7\u30ec\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\uff08\u306b\u3093\u306b\u304f\u3001\u30d0\u30ca\u30ca\uff09\u3092\u6442\u53d6\u3002<\/strong><\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u306e\u6442\u53d6\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7\u30ea\u30b9\u30af\u3092\u4f4e\u6e1b\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/www.sciencedirect.com\/\">sciencedirect.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\uff083\uff09\u74b0\u5883\u8981\u56e0\u306e\u6700\u9069\u5316\u306b\u3088\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632<\/strong><\/h3>\n\n\n\n<p>\u74b0\u5883\u8981\u56e0\u306f\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u3068\u76f8\u4e92\u4f5c\u7528\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u3005\u306e\u4f53\u8cea\u306b\u5408\u308f\u305b\u305f\u74b0\u5883\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u74b0\u5883\u8abf\u6574<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>HLA-DRB1\u306e\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong>\uff08\u82b1\u7c89\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\uff09 \u2192 \u7a7a\u6c17\u6e05\u6d44\u6a5f\u3084\u82b1\u7c89\u30d5\u30a3\u30eb\u30bf\u30fc\u3092\u6d3b\u7528\u3057\u3001\u5c4b\u5185\u306e\u82b1\u7c89\u91cf\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3002<\/li>\n\n\n\n<li><strong>TSLP\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u4eba<\/strong>\uff08\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\uff09 \u2192 \u4f4e\u523a\u6fc0\u306e\u30b9\u30ad\u30f3\u30b1\u30a2\u88fd\u54c1\u3092\u9078\u629e\u3057\u3001\u808c\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u5f37\u5316\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7814\u7a76\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5ba4\u5185\u74b0\u5883\u306e\u7ba1\u7406\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u306e\u8efd\u6e1b\u306b\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b<\/strong>\uff08\u53c2\u8003\uff1a<a href=\"https:\/\/jamanetwork.com\/\">jamanetwork.com<\/a>\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<p><strong>\u307e\u3068\u3081<\/strong><\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u30ea\u30b9\u30af\u8a55\u4fa1\u3084\u500b\u5225\u5316\u6cbb\u7642\u304c\u53ef\u80fd\u306b\u306a\u308a\u3001\u767a\u75c7\u4e88\u9632\u3084\u75c7\u72b6\u7ba1\u7406\u304c\u3088\u308a\u52b9\u679c\u7684\u306b\u884c\u3048\u307e\u3059\u3002\u98df\u4e8b\u3084\u8178\u5185\u74b0\u5883\u306e\u8abf\u6574\u3001\u74b0\u5883\u8981\u56e0\u306e\u6700\u9069\u5316\u3001AI\u3092\u6d3b\u7528\u3057\u305f\u7ba1\u7406\u30b7\u30b9\u30c6\u30e0\u306a\u3069\u3001\u6700\u65b0\u306e\u79d1\u5b66\u6280\u8853\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u5bfe\u7b56\u306f\u5927\u304d\u304f\u9032\u5316\u3057\u3066\u3044\u307e\u3059\u3002\u4eca\u5f8c\u3001\u907a\u4f1d\u5b50\u7de8\u96c6\u3084\u30b2\u30ce\u30e0\u533b\u7642\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u3055\u3089\u306a\u308b\u6cbb\u7642\u306e\u53ef\u80fd\u6027\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u7684\u8981\u56e0\u304c\u8907\u96d1\u306b\u7d61\u307f\u5408\u3063\u3066\u767a\u75c7\u3057\u307e\u3059\u3002\u8fd1\u5e74\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306b\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u306b\u57fa\u3065\u304f\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306e\u7406\u89e3\u3068 [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":6136,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-6135","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-technology"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/6135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/comments?post=6135"}],"version-history":[{"count":1,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/6135\/revisions"}],"predecessor-version":[{"id":6178,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/6135\/revisions\/6178"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media\/6136"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media?parent=6135"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/categories?post=6135"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/tags?post=6135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}