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class=\"wp-block-heading\"><strong>HLA\u907a\u4f1d\u5b50\u3068\u85ac\u7269\u6027\u904e\u654f\u75c7<\/strong><\/h2>\n\n\n\n<p>\u30d2\u30c8\u767d\u8840\u7403\u578b\u6297\u539f\uff08HLA\uff09\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306f\u3001\u85ac\u7269\u6027\u904e\u654f\u75c7\u306e\u767a\u75c7\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u5b9a\u306eHLA\u907a\u4f1d\u5b50\u3092\u6301\u3064\u60a3\u8005\u306f\u3001\u7279\u5b9a\u306e\u85ac\u5264\u306b\u5bfe\u3057\u3066\u91cd\u7be4\u306a\u76ae\u819a\u53cd\u5fdc\u3092\u793a\u3059\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001HLA-B<em>57:01\u3092\u6301\u3064\u60a3\u8005\u304cHIV\u6cbb\u7642\u85ac\u30a2\u30d0\u30ab\u30d3\u30eb\u3092\u670d\u7528\u3057\u305f\u5834\u5408\u3001\u91cd\u7be4\u306a\u904e\u654f\u75c7\u53cd\u5fdc\u3092\u8d77\u3053\u3059\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u305f\u3081\u3001\u30a2\u30d0\u30ab\u30d3\u30eb\u6295\u4e0e\u524d\u306bHLA-B<\/em>57:01\u306e\u6709\u7121\u3092\u691c\u67fb\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d3b\u7528\u306b\u3088\u308a\u3001\u85ac\u7269\u6027\u904e\u654f\u75c7\u306e\u4e88\u9632\u304c\u53ef\u80fd\u3068\u306a\u308a\u3001\u60a3\u8005\u306e\u5b89\u5168\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u9650\u754c\u3068\u8ab2\u984c<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u3001\u85ac\u7269\u53cd\u5fdc\u6027\u3084\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u306e\u4e88\u6e2c\u306b\u6709\u7528\u306a\u30c4\u30fc\u30eb\u3067\u3059\u304c\u3001\u3044\u304f\u3064\u304b\u306e\u9650\u754c\u3084\u8ab2\u984c\u3082\u5b58\u5728\u3057\u307e\u3059\u3002\u307e\u305a\u3001\u907a\u4f1d\u5b50\u591a\u578b\u306e\u983b\u5ea6\u3084\u5f71\u97ff\u306f\u4eba\u7a2e\u3084\u6c11\u65cf\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u305f\u3081\u3001\u7279\u5b9a\u306e\u96c6\u56e3\u306b\u304a\u3051\u308b\u30c7\u30fc\u30bf\u306e\u84c4\u7a4d\u304c\u5fc5\u8981\u3067\u3059\u3002\u307e\u305f\u3001\u907a\u4f1d\u5b50\u4ee5\u5916\u306e\u8981\u56e0\u3001\u4f8b\u3048\u3070\u74b0\u5883\u8981\u56e0\u3084\u4ed6\u306e\u75be\u60a3\u3001\u4f75\u7528\u85ac\u306a\u3069\u3082\u85ac\u7269\u53cd\u5fdc\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u305f\u3081\u3001\u7dcf\u5408\u7684\u306a\u8a55\u4fa1\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u81e8\u5e8a\u73fe\u5834\u3067\u3069\u306e\u3088\u3046\u306b\u6d3b\u7528\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3084\u6559\u80b2\u306e\u6574\u5099\u3082\u91cd\u8981\u306a\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d3b\u7528\u4e8b\u4f8b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/31406231_m-1024x683.jpg\" alt=\"\u9178\u7d20\u30de\u30b9\u30af\u3092\u3057\u3066\u7720\u308b\u5973\u306e\u5b50\" class=\"wp-image-6392\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31406231_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31406231_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31406231_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31406231_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/31406231_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u304c\u3093\u6cbb\u7642\u306b\u304a\u3051\u308b\u5fdc\u7528<\/strong><\/h3>\n\n\n\n<p>\u304c\u3093\u6cbb\u7642\u3067\u306f\u3001\u60a3\u8005\u3054\u3068\u306b\u6700\u9069\u306a\u85ac\u5264\u3092\u9078\u629e\u3059\u308b\u305f\u3081\u306b\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u5e83\u304f\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001HER2\u907a\u4f1d\u5b50\u306e\u5897\u5e45\u304c\u78ba\u8a8d\u3055\u308c\u305f\u4e73\u304c\u3093\u60a3\u8005\u306b\u306f\u3001\u5206\u5b50\u6a19\u7684\u85ac\u3067\u3042\u308b\u30c8\u30e9\u30b9\u30c4\u30ba\u30de\u30d6\uff08\u30cf\u30fc\u30bb\u30d7\u30c1\u30f3\uff09\u304c\u6709\u52b9\u3067\u3059\u3002\u307e\u305f\u3001EGFR\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u80ba\u304c\u3093\u60a3\u8005\u306b\u306f\u3001\u30b2\u30d5\u30a3\u30c1\u30cb\u30d6\uff08\u30a4\u30ec\u30c3\u30b5\uff09\u3084\u30a8\u30eb\u30ed\u30c1\u30cb\u30d6\uff08\u30bf\u30eb\u30bb\u30d0\uff09\u306a\u3069\u306eEGFR\u963b\u5bb3\u85ac\u304c\u52b9\u679c\u3092\u793a\u3057\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u3001\u304c\u3093\u306e\u907a\u4f1d\u5b50\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u6cbb\u7642\u52b9\u679c\u306e\u9ad8\u3044\u85ac\u5264\u3092\u9078\u629e\u3057\u3001\u526f\u4f5c\u7528\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001\u6297\u304c\u3093\u5264\u306b\u3088\u308b\u526f\u4f5c\u7528\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u3082\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30d5\u30eb\u30aa\u30ed\u30a6\u30e9\u30b7\u30eb\uff085-FU\uff09\u3084\u30ab\u30da\u30b7\u30bf\u30d3\u30f3\u3068\u3044\u3063\u305f\u6297\u304c\u3093\u5264\u306e\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3059\u308bDPYD\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u60a3\u8005\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u85ac\u5264\u306e\u526f\u4f5c\u7528\u304c\u5f37\u304f\u51fa\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u305f\u3081\u3001DPYD\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u60a3\u8005\u306b\u306f\u6295\u4e0e\u91cf\u306e\u8abf\u6574\u3084\u4ee3\u66ff\u85ac\u306e\u9078\u629e\u304c\u63a8\u5968\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u7cbe\u795e\u75be\u60a3\u6cbb\u7642\u306b\u304a\u3051\u308b\u5fdc\u7528<\/strong><\/h3>\n\n\n\n<p>\u3046\u3064\u75c5\u3084\u7d71\u5408\u5931\u8abf\u75c7\u306a\u3069\u306e\u7cbe\u795e\u75be\u60a3\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u3082\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6297\u3046\u3064\u85ac\u3084\u6297\u7cbe\u795e\u75c5\u85ac\u306e\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3059\u308bCYP2C19\u3084CYP2D6\u306e\u907a\u4f1d\u5b50\u591a\u578b\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u85ac\u306e\u52b9\u679c\u3084\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u3092\u4e88\u6e2c\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001CYP2C19\u306e\u4ee3\u8b1d\u80fd\u529b\u304c\u4f4e\u3044\u300cPM\uff08Poor Metabolizer\uff09\u300d\u578b\u306e\u60a3\u8005\u3067\u306f\u3001\u9078\u629e\u7684\u30bb\u30ed\u30c8\u30cb\u30f3\u518d\u53d6\u308a\u8fbc\u307f\u963b\u5bb3\u85ac\uff08SSRI\uff09\u3067\u3042\u308b\u30a8\u30b9\u30b7\u30bf\u30ed\u30d7\u30e9\u30e0\uff08\u30ec\u30af\u30b5\u30d7\u30ed\uff09\u306e\u8840\u4e2d\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u3001\u526f\u4f5c\u7528\u304c\u5f37\u304f\u51fa\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001PM\u578b\u306e\u60a3\u8005\u306b\u306f\u901a\u5e38\u3088\u308a\u3082\u4f4e\u7528\u91cf\u3067\u306e\u6295\u4e0e\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001CYP2D6\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u300cUM\uff08Ultra-rapid Metabolizer\uff09\u300d\u578b\u306e\u60a3\u8005\u3067\u306f\u3001\u4e00\u90e8\u306e\u6297\u7cbe\u795e\u75c5\u85ac\u306e\u4ee3\u8b1d\u304c\u901f\u304f\u306a\u308a\u3001\u5341\u5206\u306a\u6cbb\u7642\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u3044\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u60c5\u5831\u3092\u4e8b\u524d\u306b\u628a\u63e1\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u9069\u5207\u306a\u85ac\u5264\u9078\u629e\u3084\u6295\u4e0e\u91cf\u306e\u8abf\u6574\u304c\u53ef\u80fd\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u5fc3\u8840\u7ba1\u75be\u60a3\u6cbb\u7642\u306b\u304a\u3051\u308b\u5fdc\u7528<\/strong><\/h3>\n\n\n\n<p>\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u3082\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u7279\u306b\u3001\u6297\u8840\u5c0f\u677f\u85ac\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\uff08\u30d7\u30e9\u30d3\u30c3\u30af\u30b9\uff09\u306e\u52b9\u679c\u306f\u3001CYP2C19\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306b\u3088\u3063\u3066\u5927\u304d\u304f\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002CYP2C19\u306e\u4ee3\u8b1d\u80fd\u529b\u304c\u4f4e\u3044\u60a3\u8005\u3067\u306f\u3001\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u306e\u6d3b\u6027\u5316\u304c\u4e0d\u5341\u5206\u3068\u306a\u308a\u3001\u8840\u6813\u5f62\u6210\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u305f\u3081\u3001CYP2C19\u306e\u4ee3\u8b1d\u80fd\u529b\u304c\u4f4e\u3044\u60a3\u8005\u306b\u306f\u3001\u4ee3\u66ff\u85ac\u3067\u3042\u308b\u30d7\u30e9\u30b9\u30b0\u30ec\u30eb\uff08\u30a8\u30d5\u30a3\u30a8\u30f3\u30c8\uff09\u3084\u30c1\u30ab\u30b0\u30ec\u30ed\u30eb\uff08\u30d6\u30ea\u30ea\u30f3\u30bf\uff09\u306e\u4f7f\u7528\u304c\u63a8\u5968\u3055\u308c\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30b9\u30bf\u30c1\u30f3\u7cfb\u85ac\u5264\u306e\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u3082\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002SLCO1B1\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570\u3092\u6301\u3064\u60a3\u8005\u3067\u306f\u3001\u30b9\u30bf\u30c1\u30f3\u7cfb\u85ac\u5264\u306b\u3088\u308b\u7b4b\u969c\u5bb3\uff08\u6a2a\u7d0b\u7b4b\u878d\u89e3\u75c7\uff09\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306a\u60a3\u8005\u306b\u306f\u3001\u3088\u308a\u5b89\u5168\u6027\u306e\u9ad8\u3044\u85ac\u5264\u306e\u9078\u629e\u3084\u4f4e\u7528\u91cf\u3067\u306e\u4f7f\u7528\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6700\u65b0\u7814\u7a76\u3068\u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-1024x683.jpg\" alt=\"\u5b9f\u9a13\u3092\u3059\u308b\u7814\u7a76\u8005\u30b0\u30eb\u30fc\u30d7\" class=\"wp-image-6399\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u6280\u8853\u306f\u65e5\u3005\u9032\u5316\u3057\u3066\u304a\u308a\u3001\u85ac\u7269\u53cd\u5fdc\u6027\u3084\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u306e\u4e88\u6e2c\u7cbe\u5ea6\u3082\u5411\u4e0a\u3057\u3066\u3044\u307e\u3059\u3002\u8fd1\u5e74\u3001\u30b2\u30ce\u30e0\u30ef\u30a4\u30c9\u95a2\u9023\u89e3\u6790\uff08GWAS\uff09\u3084\u5168\u30b2\u30ce\u30e0\u30b7\u30fc\u30af\u30a8\u30f3\u30b7\u30f3\u30b0\uff08WGS\uff09\u3092\u7528\u3044\u305f\u5927\u898f\u6a21\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u65b0\u305f\u306a\u907a\u4f1d\u5b50\u591a\u578b\u3068\u85ac\u7269\u53cd\u5fdc\u6027\u306e\u95a2\u9023\u304c\u6b21\u3005\u3068\u767a\u898b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u6700\u8fd1\u306e\u7814\u7a76\u3067\u306f\u3001\u6297\u304c\u3093\u5264\u306e\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u7684\u611f\u53d7\u6027\u304c\u3001CYP3A4\u3084ABCB1\u3068\u3044\u3063\u305f\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306b\u3088\u3063\u3066\u5f71\u97ff\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6297\u708e\u75c7\u85ac\uff08NSAIDs\uff09\u306b\u5bfe\u3059\u308b\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u304c\u3001PTGS2\u3084CYP2C9\u306e\u907a\u4f1d\u5b50\u591a\u578b\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u4eba\u5de5\u77e5\u80fd\uff08AI\uff09\u3092\u6d3b\u7528\u3057\u305f\u85ac\u7269\u5fdc\u7b54\u4e88\u6e2c\u30e2\u30c7\u30eb\u306e\u958b\u767a\u3082\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002AI\u6280\u8853\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3060\u3051\u3067\u306a\u304f\u3001\u5e74\u9f62\u3001\u6027\u5225\u3001\u751f\u6d3b\u7fd2\u6163\u3001\u4f75\u7528\u85ac\u306a\u3069\u306e\u591a\u69d8\u306a\u30c7\u30fc\u30bf\u3092\u7d71\u5408\u7684\u306b\u89e3\u6790\u3057\u3001\u3088\u308a\u7cbe\u5ea6\u306e\u9ad8\u3044\u4e88\u6e2c\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u5c06\u6765\u7684\u306b\u306f\u3001AI\u3068\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u500b\u5225\u5316\u533b\u7642\u304c\u3055\u3089\u306b\u767a\u5c55\u3057\u3001\u3088\u308a\u5b89\u5168\u3067\u52b9\u679c\u7684\u306a\u85ac\u7269\u7642\u6cd5\u304c\u5b9f\u73fe\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u53c2\u8003\u6587\u732e\u30fb\u7814\u7a76\u7d50\u679c\u306e\u30ea\u30f3\u30af<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5688532\/\">Pharmacogenomics and Personalized Medicine<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/cpicpgx.org\/\">Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3522180\/\">Genome-Wide Association Studies in Drug Response<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6367403\/\">Pharmacogenetics of Antidepressants<\/a><\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u5b9f\u65bd\u65b9\u6cd5\u3068\u73fe\u72b6<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d41\u308c<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u3001\u4e00\u822c\u7684\u306b\u4ee5\u4e0b\u306e\u6d41\u308c\u3067\u5b9f\u65bd\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u691c\u67fb\u306e\u5bfe\u8c61\u907a\u4f1d\u5b50\u306e\u6c7a\u5b9a<\/strong><strong><br><\/strong>\u60a3\u8005\u306e\u75c5\u6b74\u3084\u670d\u7528\u4e2d\u306e\u85ac\u5264\u3092\u8003\u616e\u3057\u3001\u691c\u67fb\u3059\u3079\u304d\u907a\u4f1d\u5b50\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u6297\u304c\u3093\u5264\u306e\u52b9\u679c\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306eUGT1A1\u907a\u4f1d\u5b50\u691c\u67fb\u3084\u3001\u6297\u8840\u5c0f\u677f\u85ac\u306e\u6709\u52b9\u6027\u3092\u8a55\u4fa1\u3059\u308bCYP2C19\u907a\u4f1d\u5b50\u691c\u67fb\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u691c\u4f53\u306e\u63a1\u53d6<\/strong><strong><br><\/strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u4e3b\u306b\u8840\u6db2\u3001\u553e\u6db2\u3001\u307e\u305f\u306f\u53e3\u8154\u7c98\u819c\u306e\u7d30\u80de\u3092\u63a1\u53d6\u3059\u308b\u3053\u3068\u3067\u884c\u308f\u308c\u307e\u3059\u3002\u975e\u4fb5\u8972\u7684\u306a\u65b9\u6cd5\u3068\u3057\u3066\u3001\u982c\u306e\u5185\u5074\u3092\u3053\u3059\u3063\u3066\u7d30\u80de\u3092\u63a1\u53d6\u3059\u308b\u30b9\u30ef\u30d6\u6cd5\u304c\u4e00\u822c\u7684\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>DNA\u62bd\u51fa\u3068\u89e3\u6790<\/strong><strong><br><\/strong>\u63a1\u53d6\u3057\u305f\u691c\u4f53\u304b\u3089DNA\u3092\u62bd\u51fa\u3057\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u9818\u57df\u3092\u89e3\u6790\u3057\u307e\u3059\u3002\u89e3\u6790\u624b\u6cd5\u306b\u306fPCR\uff08\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u9023\u9396\u53cd\u5fdc\uff09\u3084\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\u304c\u7528\u3044\u3089\u308c\u307e\u3059\u3002\u8fd1\u5e74\u3067\u306f\u3001\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u6280\u8853\u3092\u6d3b\u7528\u3057\u305f\u9ad8\u7cbe\u5ea6\u306e\u907a\u4f1d\u5b50\u89e3\u6790\u3082\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u7d50\u679c\u306e\u89e3\u91c8\u3068\u533b\u5e2b\u306b\u3088\u308b\u5224\u65ad<\/strong><strong><br><\/strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u3082\u3068\u306b\u3001\u533b\u5e2b\u304c\u9069\u5207\u306a\u85ac\u5264\u9078\u629e\u3084\u6295\u4e0e\u91cf\u306e\u8abf\u6574\u3092\u884c\u3044\u307e\u3059\u3002\u60a3\u8005\u3054\u3068\u306b\u7570\u306a\u308b\u85ac\u7269\u4ee3\u8b1d\u306e\u7279\u6027\u3092\u8003\u616e\u3057\u3001\u6700\u9069\u306a\u6cbb\u7642\u65b9\u91dd\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002<\/li>\n<\/ol>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u65e5\u672c\u306b\u304a\u3051\u308b\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u666e\u53ca\u72b6\u6cc1<\/strong><\/h3>\n\n\n\n<p>\u65e5\u672c\u306b\u304a\u3044\u3066\u3082\u3001\u85ac\u7269\u7642\u6cd5\u306e\u500b\u5225\u5316\u3092\u76ee\u7684\u3068\u3057\u305f\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u5f90\u3005\u306b\u666e\u53ca\u3057\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u539a\u751f\u52b4\u50cd\u7701\u306f\u3001\u7279\u5b9a\u306e\u85ac\u5264\u306b\u5bfe\u3059\u308b\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u4fdd\u967a\u9069\u7528\u3068\u3059\u308b\u30b1\u30fc\u30b9\u3092\u5897\u3084\u3057\u3066\u304a\u308a\u3001\u4f8b\u3048\u3070\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u691c\u67fb\u304c\u516c\u7684\u533b\u7642\u4fdd\u967a\u306e\u5bfe\u8c61\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CYP2C19\u907a\u4f1d\u5b50\u691c\u67fb\uff08\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u306e\u52b9\u679c\u4e88\u6e2c\uff09<\/strong><\/li>\n\n\n\n<li><strong>UGT1A1\u907a\u4f1d\u5b50\u691c\u67fb\uff08\u30a4\u30ea\u30ce\u30c6\u30ab\u30f3\u306e\u526f\u4f5c\u7528\u4e88\u6e2c\uff09<\/strong><\/li>\n\n\n\n<li><strong>HLA-B*15:02\u907a\u4f1d\u5b50\u691c\u67fb\uff08\u30ab\u30eb\u30d0\u30de\u30bc\u30d4\u30f3\u306e\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u8a55\u4fa1\uff09<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u65e5\u672c\u3067\u306f\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u8a8d\u77e5\u5ea6\u304c\u6b27\u7c73\u306b\u6bd4\u3079\u3066\u307e\u3060\u4f4e\u304f\u3001\u4e00\u90e8\u306e\u533b\u7642\u6a5f\u95a2\u3084\u5c02\u9580\u533b\u306e\u307f\u304c\u7a4d\u6975\u7684\u306b\u6d3b\u7528\u3057\u3066\u3044\u308b\u306e\u304c\u73fe\u72b6\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u60a3\u8005\u5074\u306e\u7406\u89e3\u3092\u6df1\u3081\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6709\u7528\u6027\u3092\u5e83\u304f\u666e\u53ca\u3055\u305b\u308b\u3053\u3068\u304c\u4eca\u5f8c\u306e\u8ab2\u984c\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u502b\u7406\u7684\u30fb\u6cd5\u7684\u8ab2\u984c<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/3649133_m-1024x683.jpg\" alt=\"\" class=\"wp-image-5848\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/3649133_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/3649133_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/3649133_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/3649133_m-1536x1025.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/3649133_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u60c5\u5831\u306e\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u4fdd\u8b77<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u5b9f\u65bd\u3059\u308b\u969b\u306b\u306f\u3001\u500b\u4eba\u306e\u907a\u4f1d\u60c5\u5831\u304c\u53b3\u91cd\u306b\u7ba1\u7406\u3055\u308c\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u3001\u65e5\u672c\u3067\u306f\u300c\u30b2\u30ce\u30e0\u533b\u7642\u306b\u95a2\u3059\u308b\u502b\u7406\u6307\u91dd\u300d\u3084\u300c\u500b\u4eba\u60c5\u5831\u4fdd\u8b77\u6cd5\u300d\u306b\u57fa\u3065\u304d\u3001\u907a\u4f1d\u60c5\u5831\u306e\u53d6\u308a\u6271\u3044\u306b\u95a2\u3059\u308b\u30eb\u30fc\u30eb\u304c\u5b9a\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u5177\u4f53\u7684\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u70b9\u304c\u91cd\u8981\u8996\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u907a\u4f1d\u60c5\u5831\u306e\u7b2c\u4e09\u8005\u63d0\u4f9b\u306e\u5236\u9650<\/strong><strong><br><\/strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u306f\u3001\u60a3\u8005\u306e\u540c\u610f\u306a\u3057\u306b\u4fdd\u967a\u4f1a\u793e\u3084\u96c7\u7528\u4e3b\u306a\u3069\u306e\u7b2c\u4e09\u8005\u306b\u63d0\u4f9b\u3057\u3066\u306f\u306a\u3089\u306a\u3044\u3002<\/li>\n\n\n\n<li><strong>\u691c\u67fb\u7d50\u679c\u306e\u9069\u5207\u306a\u8aac\u660e\u3068\u30a4\u30f3\u30d5\u30a9\u30fc\u30e0\u30c9\u30fb\u30b3\u30f3\u30bb\u30f3\u30c8<\/strong><strong><br><\/strong>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u53d7\u3051\u308b\u524d\u306b\u3001\u691c\u67fb\u306e\u76ee\u7684\u3084\u7d50\u679c\u304c\u53ca\u307c\u3059\u5f71\u97ff\u306b\u3064\u3044\u3066\u5341\u5206\u306a\u8aac\u660e\u3092\u884c\u3044\u3001\u60a3\u8005\u306e\u540c\u610f\u3092\u5f97\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>\u30c7\u30fc\u30bf\u306e\u5b89\u5168\u306a\u7ba1\u7406<\/strong><strong><br><\/strong>\u96fb\u5b50\u30ab\u30eb\u30c6\u3084\u30af\u30e9\u30a6\u30c9\u30b5\u30fc\u30d3\u30b9\u3092\u5229\u7528\u3059\u308b\u5834\u5408\u3001\u907a\u4f1d\u60c5\u5831\u306e\u6f0f\u6d29\u30ea\u30b9\u30af\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u305f\u3081\u306e\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3\u5bfe\u7b56\u304c\u6c42\u3081\u3089\u308c\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u751f\u547d\u4fdd\u967a\u3068\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u6d77\u5916\u3067\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u304c\u751f\u547d\u4fdd\u967a\u306e\u52a0\u5165\u53ef\u5426\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u3053\u3068\u3067\u5c06\u6765\u7684\u306a\u75be\u60a3\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3068\u5224\u65ad\u3055\u308c\u308b\u3068\u3001\u4fdd\u967a\u6599\u304c\u9ad8\u304f\u306a\u308b\u3001\u307e\u305f\u306f\u52a0\u5165\u3092\u65ad\u3089\u308c\u308b\u3068\u3044\u3063\u305f\u30b1\u30fc\u30b9\u304c\u61f8\u5ff5\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u65e5\u672c\u3067\u306f\u73fe\u6642\u70b9\u3067\u3001\u751f\u547d\u4fdd\u967a\u4f1a\u793e\u304c\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u52a0\u5165\u5be9\u67fb\u306b\u5229\u7528\u3059\u308b\u3053\u3068\u306f\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u4eca\u5f8c\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u4e00\u822c\u5316\u3059\u308b\u306b\u3064\u308c\u3001\u502b\u7406\u7684\u306a\u8b70\u8ad6\u304c\u5fc5\u8981\u3068\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u3068AI\u306e\u878d\u5408<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. AI\u3092\u6d3b\u7528\u3057\u305f\u85ac\u7269\u5fdc\u7b54\u4e88\u6e2c<\/strong><\/h3>\n\n\n\n<p>\u8fd1\u5e74\u3001\u4eba\u5de5\u77e5\u80fd\uff08AI\uff09\u306e\u9032\u5316\u306b\u3088\u308a\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u3082\u3068\u306b\u3057\u305f\u85ac\u7269\u5fdc\u7b54\u4e88\u6e2c\u306e\u7cbe\u5ea6\u304c\u5411\u4e0a\u3057\u3066\u3044\u307e\u3059\u3002AI\u306f\u3001\u5927\u91cf\u306e\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u3068\u81e8\u5e8a\u30c7\u30fc\u30bf\u3092\u89e3\u6790\u3057\u3001\u500b\u3005\u306e\u60a3\u8005\u306b\u6700\u9069\u306a\u85ac\u5264\u3084\u6295\u4e0e\u91cf\u3092\u63d0\u6848\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u30b7\u30b9\u30c6\u30e0\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>IBM Watson for Genomics<\/strong><strong><br><\/strong>AI\u3092\u6d3b\u7528\u3057\u3066\u304c\u3093\u60a3\u8005\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u89e3\u6790\u3057\u3001\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u3092\u63d0\u6848\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u3002<\/li>\n\n\n\n<li><strong>DeepMind\u306eAlphaFold<\/strong><strong><br><\/strong>\u305f\u3093\u3071\u304f\u8cea\u306e\u69cb\u9020\u4e88\u6e2c\u3092\u884c\u3044\u3001\u85ac\u5264\u30bf\u30fc\u30b2\u30c3\u30c8\u306e\u7279\u5b9a\u306b\u8ca2\u732e\u3059\u308b\u6280\u8853\u3002<\/li>\n\n\n\n<li><strong>\u6a5f\u68b0\u5b66\u7fd2\u3092\u7528\u3044\u305f\u85ac\u7269\u4ee3\u8b1d\u4e88\u6e2c\u30e2\u30c7\u30eb<\/strong><strong><br><\/strong>\u907a\u4f1d\u5b50\u591a\u578b\u3060\u3051\u3067\u306a\u304f\u3001\u5e74\u9f62\u3084\u751f\u6d3b\u7fd2\u6163\u306a\u3069\u306e\u8981\u56e0\u3082\u8003\u616e\u3057\u3001\u3088\u308a\u500b\u5225\u5316\u3055\u308c\u305f\u85ac\u7269\u7642\u6cd5\u3092\u63d0\u6848\u3002<\/li>\n<\/ul>\n\n\n\n<p>AI\u3068\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u5f93\u6765\u306e\u624b\u6cd5\u3088\u308a\u3082\u7cbe\u5ea6\u306e\u9ad8\u3044\u500b\u5225\u5316\u533b\u7642\u304c\u5b9f\u73fe\u3057\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u3068\u306e\u95a2\u9023<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/2048932_m-1024x683.jpg\" alt=\"\u8a66\u9a13\u7ba1\u3092\u6301\u3064\u7814\u7a76\u8005\" class=\"wp-image-6406\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2048932_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2048932_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2048932_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2048932_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2048932_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u9032\u5316\u3059\u308b\u4e00\u65b9\u3067\u3001\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\uff08CRISPR-Cas9\u306a\u3069\uff09\u306e\u767a\u5c55\u3082\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u4fee\u6b63\u3057\u3001\u85ac\u7269\u4ee3\u8b1d\u80fd\u529b\u3092\u6539\u5584\u3059\u308b\u8a66\u307f\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u907a\u4f1d\u5b50\u7de8\u96c6\u306b\u3088\u3063\u3066CYP2D6\u3084CYP2C19\u306e\u6a5f\u80fd\u3092\u8abf\u6574\u3057\u3001\u7279\u5b9a\u306e\u85ac\u5264\u306b\u5bfe\u3059\u308b\u53cd\u5fdc\u3092\u6700\u9069\u5316\u3059\u308b\u7814\u7a76\u304c\u9032\u884c\u4e2d\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4eca\u5f8c\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3068\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u304c\u7d71\u5408\u3055\u308c\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u9ad8\u5ea6\u306a\u500b\u5225\u5316\u533b\u7642\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u502b\u7406\u7684\u306a\u554f\u984c\u3084\u898f\u5236\u306e\u6574\u5099\u304c\u5fc5\u8981\u3067\u3042\u308a\u3001\u614e\u91cd\u306a\u8b70\u8ad6\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u30b3\u30b9\u30c8\u3068\u7d4c\u6e08\u7684\u5074\u9762<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u8cbb\u7528\u3068\u4fdd\u967a\u9069\u7528<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u8cbb\u7528\u306f\u3001\u691c\u67fb\u306e\u7a2e\u985e\u3084\u89e3\u6790\u306e\u8a73\u7d30\u5ea6\u306b\u3088\u3063\u3066\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002\u4e00\u822c\u7684\u306a\u85ac\u7406\u907a\u4f1d\u5b66\u7684\u691c\u67fb\u3067\u306f\u6570\u5343\u5186\u304b\u3089\u6570\u4e07\u5186\u7a0b\u5ea6\u306e\u8cbb\u7528\u304c\u304b\u304b\u308a\u307e\u3059\u304c\u3001\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\u3092\u7528\u3044\u305f\u5305\u62ec\u7684\u306a\u907a\u4f1d\u5b50\u89e3\u6790\u3067\u306f\u6570\u5341\u4e07\u5186\u4ee5\u4e0a\u304b\u304b\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u65e5\u672c\u306b\u304a\u3044\u3066\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u533b\u7642\u4fdd\u967a\u306e\u9069\u7528\u5bfe\u8c61\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u691c\u67fb\u306f\u4fdd\u967a\u9069\u7528\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CYP2C19\u907a\u4f1d\u5b50\u691c\u67fb\uff08\u6297\u8840\u5c0f\u677f\u85ac\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u306e\u52b9\u679c\u4e88\u6e2c\uff09<\/strong><\/li>\n\n\n\n<li><strong>UGT1A1\u907a\u4f1d\u5b50\u691c\u67fb\uff08\u6297\u304c\u3093\u5264\u30a4\u30ea\u30ce\u30c6\u30ab\u30f3\u306e\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u8a55\u4fa1\uff09<\/strong><\/li>\n\n\n\n<li><strong>HLA-B*57:01\u907a\u4f1d\u5b50\u691c\u67fb\uff08\u30a2\u30d0\u30ab\u30d3\u30eb\u306b\u3088\u308b\u91cd\u7be4\u306a\u904e\u654f\u75c7\u30ea\u30b9\u30af\u8a55\u4fa1\uff09<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u591a\u304f\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u4f9d\u7136\u3068\u3057\u3066\u81ea\u7531\u8a3a\u7642\u3067\u884c\u308f\u308c\u3066\u304a\u308a\u3001\u8cbb\u7528\u8ca0\u62c5\u304c\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4eca\u5f8c\u3001\u500b\u5225\u5316\u533b\u7642\u306e\u666e\u53ca\u306b\u4f34\u3044\u3001\u4fdd\u967a\u9069\u7528\u306e\u7bc4\u56f2\u304c\u62e1\u5927\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u8cbb\u7528\u5bfe\u52b9\u679c<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u5b9f\u65bd\u3059\u308b\u3053\u3068\u3067\u3001\u85ac\u7269\u7642\u6cd5\u306e\u9069\u6b63\u5316\u3084\u526f\u4f5c\u7528\u306e\u4e88\u9632\u304c\u53ef\u80fd\u3068\u306a\u308a\u3001\u533b\u7642\u30b3\u30b9\u30c8\u306e\u524a\u6e1b\u306b\u3064\u306a\u304c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u6297\u304c\u3093\u5264\u6cbb\u7642\u306b\u304a\u3044\u3066\u4e0d\u9069\u5207\u306a\u85ac\u5264\u3092\u56de\u907f\u3067\u304d\u308c\u3070\u3001\u7121\u99c4\u306a\u6cbb\u7642\u8cbb\u3092\u524a\u6e1b\u3067\u304d\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u60a3\u8005\u306eQOL\uff08\u751f\u6d3b\u306e\u8cea\uff09\u5411\u4e0a\u306b\u3082\u5bc4\u4e0e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u5c0e\u5165\u30b3\u30b9\u30c8\u3084\u691c\u67fb\u6a5f\u95a2\u306e\u904b\u55b6\u8cbb\u7528\u304c\u9ad8\u984d\u3067\u3042\u308b\u305f\u3081\u3001\u7d4c\u6e08\u7684\u306a\u89b3\u70b9\u304b\u3089\u305d\u306e\u666e\u53ca\u306b\u306f\u614e\u91cd\u306a\u8b70\u8ad6\u304c\u5fc5\u8981\u3067\u3059\u3002\u7279\u306b\u3001\u3069\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6a19\u6e96\u533b\u7642\u3068\u3057\u3066\u5c0e\u5165\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u306f\u3001\u8cbb\u7528\u5bfe\u52b9\u679c\u306e\u8a55\u4fa1\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u53d7\u3051\u308b\u969b\u306e\u6ce8\u610f\u70b9<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u9650\u754c\u3092\u7406\u89e3\u3059\u308b<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u6709\u7528\u306a\u60c5\u5831\u3092\u63d0\u4f9b\u3057\u307e\u3059\u304c\u3001\u3059\u3079\u3066\u306e\u85ac\u7269\u53cd\u5fdc\u3092\u5b8c\u5168\u306b\u4e88\u6e2c\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u907a\u4f1d\u7684\u8981\u56e0\u4ee5\u5916\u306b\u3082\u3001\u5e74\u9f62\u3001\u6027\u5225\u3001\u4f53\u91cd\u3001\u809d\u6a5f\u80fd\u3001\u814e\u6a5f\u80fd\u3001\u4f75\u7528\u85ac\u3001\u751f\u6d3b\u7fd2\u6163\u306a\u3069\u304c\u85ac\u7269\u5fdc\u7b54\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u306e\u307f\u3067\u6cbb\u7642\u65b9\u91dd\u3092\u6c7a\u5b9a\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u7dcf\u5408\u7684\u306a\u5224\u65ad\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u907a\u4f1d\u5b50\u591a\u578b\u304c\u85ac\u7269\u5fdc\u7b54\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306e\u7a0b\u5ea6\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u5fc5\u305a\u3057\u3082\u691c\u67fb\u7d50\u679c\u3069\u304a\u308a\u306e\u53cd\u5fdc\u304c\u51fa\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002\u305d\u306e\u305f\u3081\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u904e\u4fe1\u305b\u305a\u3001\u533b\u5e2b\u3068\u76f8\u8ac7\u3057\u306a\u304c\u3089\u6cbb\u7642\u3092\u9032\u3081\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u4fe1\u983c\u3067\u304d\u308b\u691c\u67fb\u6a5f\u95a2\u3092\u9078\u3076<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/496729_m-1024x683.jpg\" alt=\"\u63e1\u624b\u3092\u3059\u308b\u30d3\u30b8\u30cd\u30b9\u30de\u30f3\" class=\"wp-image-6413\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/496729_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/496729_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/496729_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/496729_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/496729_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u53d7\u3051\u308b\u969b\u306b\u306f\u3001\u4fe1\u983c\u3067\u304d\u308b\u691c\u67fb\u6a5f\u95a2\u3092\u9078\u3076\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u30b5\u30fc\u30d3\u30b9\u3092\u63d0\u4f9b\u3059\u308b\u6c11\u9593\u4f01\u696d\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u304c\u3001\u4e2d\u306b\u306f\u79d1\u5b66\u7684\u6839\u62e0\u304c\u4e0d\u5341\u5206\u306a\u691c\u67fb\u3092\u63d0\u4f9b\u3059\u308b\u696d\u8005\u3082\u5b58\u5728\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4fe1\u983c\u3067\u304d\u308b\u691c\u67fb\u6a5f\u95a2\u3092\u9078\u3076\u969b\u306e\u30dd\u30a4\u30f3\u30c8\u3068\u3057\u3066\u3001\u4ee5\u4e0b\u306e\u70b9\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u533b\u7642\u6a5f\u95a2\u3084\u7814\u7a76\u6a5f\u95a2\u3068\u63d0\u643a\u3057\u3066\u3044\u308b\u304b<\/strong><\/li>\n\n\n\n<li><strong>\u691c\u67fb\u65b9\u6cd5\u3084\u89e3\u6790\u624b\u6cd5\u304c\u79d1\u5b66\u7684\u306b\u59a5\u5f53\u304b<\/strong><\/li>\n\n\n\n<li><strong>\u7d50\u679c\u306e\u8aac\u660e\u304c\u5341\u5206\u306b\u63d0\u4f9b\u3055\u308c\u308b\u304b<\/strong><\/li>\n\n\n\n<li><strong>\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u4fdd\u8b77\u5bfe\u7b56\u304c\u6574\u3063\u3066\u3044\u308b\u304b<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u7279\u306b\u3001\u6d77\u5916\u306e\u691c\u67fb\u6a5f\u95a2\u3092\u5229\u7528\u3059\u308b\u5834\u5408\u306f\u3001\u30c7\u30fc\u30bf\u306e\u7ba1\u7406\u4f53\u5236\u3084\u6cd5\u7684\u4fdd\u8b77\u304c\u65e5\u672c\u3068\u7570\u306a\u308b\u305f\u3081\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30fb\u30e1\u30c7\u30a3\u30b7\u30f3\uff08\u7cbe\u5bc6\u533b\u7642\uff09\u306e\u767a\u5c55<\/strong><\/h3>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30fb\u30e1\u30c7\u30a3\u30b7\u30f3\uff08\u7cbe\u5bc6\u533b\u7642\uff09\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7cbe\u5bc6\u533b\u7642\u3068\u306f\u3001\u500b\u3005\u306e\u60a3\u8005\u306e\u907a\u4f1d\u60c5\u5831\u3084\u74b0\u5883\u8981\u56e0\u3092\u8003\u616e\u3057\u3001\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u3092\u63d0\u4f9b\u3059\u308b\u533b\u7642\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u3053\u3068\u3092\u6307\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7c73\u56fd\u3067\u306f\u3001\u30aa\u30d0\u30de\u653f\u6a29\u6642\u4ee3\u306b\u300cPrecision Medicine Initiative\uff08\u7cbe\u5bc6\u533b\u7642\u30a4\u30cb\u30b7\u30a2\u30c1\u30d6\uff09\u300d\u304c\u767a\u8868\u3055\u308c\u3001\u30b2\u30ce\u30e0\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u500b\u5225\u5316\u533b\u7642\u306e\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u307e\u3057\u305f\u3002\u65e5\u672c\u3067\u3082\u300c\u30b2\u30ce\u30e0\u533b\u7642\u63a8\u9032\u57fa\u672c\u8a08\u753b\u300d\u304c\u7b56\u5b9a\u3055\u308c\u3001\u304c\u3093\u3084\u5e0c\u5c11\u75be\u60a3\u3092\u5bfe\u8c61\u306b\u3057\u305f\u30b2\u30ce\u30e0\u533b\u7642\u304c\u63a8\u9032\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4eca\u5f8c\u3001\u30d7\u30ec\u30b7\u30b8\u30e7\u30f3\u30fb\u30e1\u30c7\u30a3\u30b7\u30f3\u304c\u4e00\u822c\u7684\u306a\u533b\u7642\u3068\u3057\u3066\u666e\u53ca\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u9ad8\u5ea6\u306a\u500b\u5225\u5316\u6cbb\u7642\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u30a6\u30a7\u30a2\u30e9\u30d6\u30eb\u30c7\u30d0\u30a4\u30b9\u3068\u306e\u9023\u643a<\/strong><\/h3>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3068\u30a6\u30a7\u30a2\u30e9\u30d6\u30eb\u30c7\u30d0\u30a4\u30b9\u306e\u9023\u643a\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u30b9\u30de\u30fc\u30c8\u30a6\u30a9\u30c3\u30c1\u3084\u5065\u5eb7\u7ba1\u7406\u30a2\u30d7\u30ea\u3092\u6d3b\u7528\u3057\u3001\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u306e\u5065\u5eb7\u30c7\u30fc\u30bf\u3068\u907a\u4f1d\u60c5\u5831\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u7cbe\u5ea6\u306e\u9ad8\u3044\u85ac\u7269\u7642\u6cd5\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u5fc3\u62cd\u6570\u3084\u8840\u5727\u3001\u8840\u7cd6\u5024\u306e\u5909\u52d5\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3057\u306a\u304c\u3089\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u8003\u616e\u3057\u305f\u85ac\u5264\u6295\u4e0e\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u3088\u308a\u500b\u5225\u5316\u3055\u308c\u305f\u6cbb\u7642\u8a08\u753b\u3092\u7acb\u3066\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u7cd6\u5c3f\u75c5\u3084\u9ad8\u8840\u5727\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306a\u3069\u306e\u6162\u6027\u75be\u60a3\u7ba1\u7406\u304c\u3088\u308a\u52b9\u679c\u7684\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u907a\u4f1d\u5b50\u6cbb\u7642\u3068\u306e\u878d\u5408<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u9032\u5316\u3068\u3068\u3082\u306b\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\u3068\u306e\u878d\u5408\u3082\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u85ac\u7269\u5fdc\u7b54\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u304c\u660e\u78ba\u306b\u306a\u308c\u3070\u3001\u305d\u308c\u3092\u4fee\u6b63\u3059\u308b\u3053\u3068\u3067\u6cbb\u7642\u52b9\u679c\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u3067\u3042\u308bCRISPR-Cas9\u3092\u7528\u3044\u3066\u3001\u85ac\u5264\u4ee3\u8b1d\u9175\u7d20\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u4fee\u6b63\u3059\u308b\u3053\u3068\u3067\u3001\u7279\u5b9a\u306e\u85ac\u5264\u306e\u526f\u4f5c\u7528\u3092\u56de\u907f\u3057\u305f\u308a\u3001\u52b9\u679c\u3092\u6700\u9069\u5316\u3057\u305f\u308a\u3059\u308b\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u5f93\u6765\u306e\u300c\u907a\u4f1d\u5b50\u306b\u5408\u308f\u305b\u305f\u85ac\u5264\u9078\u629e\u300d\u304b\u3089\u3001\u300c\u907a\u4f1d\u5b50\u81ea\u4f53\u3092\u6cbb\u7642\u3059\u308b\u300d\u3068\u3044\u3046\u65b0\u305f\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u751f\u307e\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6559\u80b2\u3068\u666e\u53ca\u306e\u91cd\u8981\u6027<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/24914789_m-1024x683.jpg\" alt=\"\u5c4b\u5185\u306b\u3044\u308b\u7537\u6027\u533b\u5e2b\u3068\u5973\u6027\u60a3\u8005\" class=\"wp-image-4589\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24914789_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24914789_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24914789_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24914789_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24914789_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u533b\u7642\u5f93\u4e8b\u8005\u306e\u6559\u80b2\u5f37\u5316<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u666e\u53ca\u306b\u306f\u3001\u533b\u7642\u5f93\u4e8b\u8005\u306e\u6559\u80b2\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u7279\u306b\u85ac\u7406\u907a\u4f1d\u5b66\u306b\u95a2\u3059\u308b\u77e5\u8b58\u3092\u6301\u3064\u533b\u5e2b\u3084\u85ac\u5264\u5e2b\u304c\u5897\u3048\u308b\u3053\u3068\u3067\u3001\u9069\u5207\u306a\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d3b\u7528\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u533b\u5b66\u90e8\u3084\u85ac\u5b66\u90e8\u306e\u30ab\u30ea\u30ad\u30e5\u30e9\u30e0\u306b\u85ac\u7406\u907a\u4f1d\u5b66\u3092\u3088\u308a\u6df1\u304f\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u306e\u5c02\u9580\u5bb6\u304c\u5897\u3048\u308b\u3053\u3068\u3067\u3001\u60a3\u8005\u304c\u691c\u67fb\u7d50\u679c\u3092\u6b63\u3057\u304f\u7406\u89e3\u3057\u3001\u9069\u5207\u306a\u6cbb\u7642\u9078\u629e\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u3053\u3068\u3082\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u4e00\u822c\u5e02\u6c11\u3078\u306e\u5553\u767a\u6d3b\u52d5<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6709\u7528\u6027\u3092\u5e83\u304f\u4e00\u822c\u306b\u77e5\u3063\u3066\u3082\u3089\u3046\u3053\u3068\u3082\u91cd\u8981\u3067\u3059\u3002\u533b\u7642\u6a5f\u95a2\u3084\u653f\u5e9c\u6a5f\u95a2\u304c\u60c5\u5831\u3092\u767a\u4fe1\u3057\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6b63\u3057\u3044\u77e5\u8b58\u3092\u5e83\u3081\u308b\u3053\u3068\u3067\u3001\u4e0d\u8981\u306a\u4e0d\u5b89\u3092\u8efd\u6e1b\u3057\u3001\u9069\u5207\u306a\u5229\u7528\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4eca\u5f8c\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u3088\u308a\u4e00\u822c\u7684\u306b\u306a\u308b\u305f\u3081\u306b\u306f\u3001\u5c02\u9580\u5bb6\u3068\u4e00\u822c\u5e02\u6c11\u306e\u53cc\u65b9\u306b\u5bfe\u3059\u308b\u6559\u80b2\u3068\u5553\u767a\u304c\u5fc5\u8981\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u672a\u6765\u3068\u671f\u5f85\u3055\u308c\u308b\u9032\u5c55<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/28721490_m-1024x585.jpg\" alt=\"\u90fd\u4f1a\u306e\u30d3\u30eb\u7fa4\u3092\u773a\u3081\u308b\u82e5\u3044\u7537\u6027\u30b5\u30e9\u30ea\u30fc\u30de\u30f3\" class=\"wp-image-5467\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/28721490_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/28721490_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/28721490_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/28721490_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/28721490_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u4eca\u5f8c\u3001\u6280\u8853\u306e\u9032\u6b69\u306b\u3088\u308a\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u30b3\u30b9\u30c8\u304c\u4e0b\u304c\u308a\u3001\u3088\u308a\u591a\u304f\u306e\u4eba\u304c\u6c17\u8efd\u306b\u53d7\u3051\u3089\u308c\u308b\u6642\u4ee3\u304c\u8a2a\u308c\u308b\u3067\u3057\u3087\u3046\u3002AI\u3068\u306e\u878d\u5408\u3084\u65b0\u305f\u306a\u907a\u4f1d\u5b50\u89e3\u6790\u6280\u8853\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u3055\u3089\u306b\u7cbe\u5ea6\u306e\u9ad8\u3044\u500b\u5225\u5316\u533b\u7642\u304c\u5b9f\u73fe\u3059\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-9c865bc2-7fff-42be-1674-ebf32331fa22\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u3001\u500b\u3005\u306e\u85ac\u7269\u53cd\u5fdc\u3084\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u3092\u4e88\u6e2c\u3057\u3001\u3088\u308a\u5b89\u5168\u3067\u52b9\u679c\u7684\u306a\u500b\u5225\u5316\u533b\u7642\u3092\u5b9f\u73fe\u3059\u308b\u91cd\u8981\u306a\u30c4\u30fc\u30eb\u3067\u3059\u3002\u3059\u3067\u306b\u304c\u3093\u6cbb\u7642\u3084\u7cbe\u795e\u75be\u60a3\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306a\u3069\u306e\u5206\u91ce\u3067\u6d3b\u7528\u3055\u308c\u3066\u304a\u308a\u3001\u4eca\u5f8c\u3055\u3089\u306b\u591a\u304f\u306e\u75be\u60a3\u3078\u306e\u5fdc\u7528\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u53d6\u308a\u6271\u3044\u306b\u306f\u502b\u7406\u7684\u30fb\u6cd5\u7684\u306a\u8ab2\u984c\u3082\u4f34\u3046\u305f\u3081\u3001\u9069\u5207\u306a\u7ba1\u7406\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u6280\u8853\u306e\u9032\u6b69\u3068\u3068\u3082\u306b\u3001\u533b\u7642\u5f93\u4e8b\u8005\u3084\u4e00\u822c\u5e02\u6c11\u3078\u306e\u6559\u80b2\u3092\u9032\u3081\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6b63\u3057\u304f\u6d3b\u7528\u3059\u308b\u74b0\u5883\u3092\u6574\u3048\u308b\u3053\u3068\u304c\u4eca\u5f8c\u306e\u8ab2\u984c\u3068\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u306f\u3058\u3081\u306b 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