{"id":696,"date":"2024-12-06T02:01:02","date_gmt":"2024-12-06T02:01:02","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=696"},"modified":"2025-02-14T08:38:17","modified_gmt":"2025-02-14T08:38:17","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e6%83%85%e5%a0%b1%e3%81%a7%e8%80%83%e3%81%88%e3%82%8b%e3%83%9b%e3%83%ab%e3%83%a2%e3%83%b3%e3%83%90%e3%83%a9%e3%83%b3%e3%82%b9%e3%81%a8%e5%bd%b1%e9%9f%bf","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e6%83%85%e5%a0%b1%e3%81%a7%e8%80%83%e3%81%88%e3%82%8b%e3%83%9b%e3%83%ab%e3%83%a2%e3%83%b3%e3%83%90%e3%83%a9%e3%83%b3%e3%82%b9%e3%81%a8%e5%bd%b1%e9%9f%bf\/","title":{"rendered":"\u907a\u4f1d\u5b50\u60c5\u5831\u3067\u8003\u3048\u308b\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3068\u5f71\u97ff"},"content":{"rendered":"\n<p>\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306f\u3001\u79c1\u305f\u3061\u306e\u5065\u5eb7\u3084\u4f53\u8abf\u3092\u5927\u304d\u304f\u5de6\u53f3\u3059\u308b\u91cd\u8981\u306a\u8981\u7d20\u3067\u3059\u3002\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u3084\u50cd\u304d\u306b\u306f\u3001\u907a\u4f1d\u5b50\u304c\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u907a\u4f1d\u7684\u306a\u9055\u3044\u306b\u3088\u3063\u3066\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u91cf\u3084\u4ee3\u8b1d\u80fd\u529b\u306b\u500b\u4eba\u5dee\u304c\u751f\u3058\u307e\u3059\u3002\u6700\u8fd1\u306e\u7814\u7a76\u3067\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u304c\u89e3\u660e\u3055\u308c\u3064\u3064\u3042\u308a\u3001\u305d\u308c\u306b\u57fa\u3065\u3044\u305f\u500b\u5225\u6700\u9069\u5316\u3055\u308c\u305f\u5065\u5eb7\u7ba1\u7406\u306e\u91cd\u8981\u6027\u304c\u9ad8\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2\u3092\u6df1\u6398\u308a\u3057\u3001\u6700\u65b0\u306e\u7814\u7a76\u7d50\u679c\u3092\u4ea4\u3048\u306a\u304c\u3089\u3001\u3069\u306e\u3088\u3046\u306b\u5065\u5eb7\u7ba1\u7406\u306b\u6d3b\u7528\u3067\u304d\u308b\u306e\u304b\u3092\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306f\u3001\u8133\u306e\u8996\u5e8a\u4e0b\u90e8\u3001\u4e0b\u5782\u4f53\u3001\u305d\u3057\u3066\u5185\u5206\u6ccc\u817a\uff08\u7532\u72b6\u817a\u3001\u526f\u814e\u3001\u5375\u5de3\u3001\u7cbe\u5de3\u306a\u3069\uff09\u304c\u76f8\u4e92\u306b\u8abf\u6574\u3059\u308b\u3053\u3068\u3067\u7dad\u6301\u3055\u308c\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u30d0\u30e9\u30f3\u30b9\u306b\u306f\u907a\u4f1d\u7684\u306a\u8981\u7d20\u304c\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u304a\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u91cf\u3084\u611f\u53d7\u6027\u3092\u5de6\u53f3\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\uff08ESR1\u30fbESR2\uff09\u3068\u30db\u30eb\u30e2\u30f3\u611f\u53d7\u6027<\/strong><\/h3>\n\n\n\n<p>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\uff08\u5973\u6027\u30db\u30eb\u30e2\u30f3\uff09\u306f\u3001\u9aa8\u5bc6\u5ea6\u306e\u7dad\u6301\u3084\u8840\u7ba1\u306e\u5065\u5eb7\u306b\u95a2\u4e0e\u3057\u3001\u5973\u6027\u306e\u5065\u5eb7\u306b\u3068\u3063\u3066\u91cd\u8981\u306a\u30db\u30eb\u30e2\u30f3\u3067\u3059\u3002\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306e\u4f5c\u7528\u306f\u3001<strong>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08ER\uff09<\/strong> \u3092\u4ecb\u3057\u3066\u767a\u63ee\u3055\u308c\u307e\u3059\u3002ER\u306b\u306f <strong>ESR1\uff08ER\u03b1\uff09<\/strong> \u3068 <strong>ESR2\uff08ER\u03b2\uff09<\/strong> \u3068\u3044\u30462\u7a2e\u985e\u306e\u907a\u4f1d\u5b50\u304c\u3042\u308a\u3001\u305d\u308c\u305e\u308c\u7570\u306a\u308b\u50cd\u304d\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>ESR1\u907a\u4f1d\u5b50\uff08ER\u03b1\uff09\u5909\u7570<\/strong> \u2192 \u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u611f\u53d7\u6027\u304c\u5909\u5316\u3057\u3001\u66f4\u5e74\u671f\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u304c\u5909\u52d5<\/li>\n\n\n\n<li><strong>ESR2\u907a\u4f1d\u5b50\uff08ER\u03b2\uff09\u5909\u7570<\/strong> \u2192 \u4e73\u304c\u3093\u3084\u9aa8\u7c97\u3057\u3087\u3046\u75c7\u306e\u30ea\u30b9\u30af\u306b\u5f71\u97ff<\/li>\n<\/ul>\n\n\n\n<p>\u907a\u4f1d\u5b50\u5909\u7570\u306b\u3088\u308a\u3001\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u4f53\u8cea\u3068\u305d\u3046\u3067\u306a\u3044\u4f53\u8cea\u306b\u5206\u304b\u308c\u308b\u305f\u3081\u3001\u500b\u5225\u306e\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u8abf\u6574\u304c\u91cd\u8981\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u4ee3\u8b1d\u95a2\u9023\u907a\u4f1d\u5b50\uff08AR\u30fbSRD5A2\uff09\u3068\u7537\u6027\u30db\u30eb\u30e2\u30f3<\/strong><\/h3>\n\n\n\n<p>\u7537\u6027\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b <strong>\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3<\/strong> \u306f\u3001\u7b4b\u8089\u306e\u6210\u9577\u3084\u6027\u6a5f\u80fd\u306b\u95a2\u4e0e\u3059\u308b\u91cd\u8981\u306a\u30db\u30eb\u30e2\u30f3\u3067\u3059\u304c\u3001\u305d\u306e\u50cd\u304d\u306f\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>AR\u907a\u4f1d\u5b50\uff08\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff09<\/strong> \u2192 \u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306e\u52b9\u679c\u3092\u6c7a\u5b9a<\/li>\n\n\n\n<li><strong>SRD5A2\u907a\u4f1d\u5b50\uff085\u03b1\u9084\u5143\u9175\u7d20\uff09<\/strong> \u2192 \u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3092\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u306b\u5909\u63db<\/li>\n<\/ul>\n\n\n\n<p>AR\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306e\u611f\u53d7\u6027\u304c\u4f4e\u4e0b\u3057\u3001\u7b4b\u8089\u306e\u767a\u9054\u3084\u7537\u6027\u6a5f\u80fd\u306e\u5909\u5316\u304c\u751f\u3058\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001SRD5A2\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001DHT\u306e\u7523\u751f\u91cf\u3092\u5de6\u53f3\u3057\u3001\u8131\u6bdb\u75c7\u3084\u524d\u7acb\u817a\u80a5\u5927\u306e\u30ea\u30b9\u30af\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u306b\u3088\u308b\u30db\u30eb\u30e2\u30f3\u4ee3\u8b1d\u306e\u500b\u4eba\u5dee<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"574\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/30574915_m-1024x574.jpg\" alt=\"\u30b3\u30fc\u30d2\u30fc\u3092\u6301\u3063\u3066\u79cb\u306e\u516c\u5712\u3092\u6563\u6b69\u3059\u308b\u5973\u6027\" class=\"wp-image-4328\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30574915_m-1024x574.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30574915_m-300x168.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30574915_m-768x430.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30574915_m-1536x861.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30574915_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30db\u30eb\u30e2\u30f3\u306f\u3001\u5206\u6ccc\u3055\u308c\u305f\u5f8c\u306b\u809d\u81d3\u3084\u814e\u81d3\u3067\u4ee3\u8b1d\u30fb\u6392\u51fa\u3055\u308c\u307e\u3059\u304c\u3001\u3053\u306e\u4ee3\u8b1d\u904e\u7a0b\u3082\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002\u7279\u306b\u3001\u809d\u81d3\u306e\u9175\u7d20\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u30db\u30eb\u30e2\u30f3\u306e\u5206\u89e3\u80fd\u529b\u304c\u7570\u306a\u308a\u3001\u8840\u4e2d\u306e\u30db\u30eb\u30e2\u30f3\u6fc3\u5ea6\u306b\u5dee\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. CYP19A1\u907a\u4f1d\u5b50\uff08\u30a2\u30ed\u30de\u30bf\u30fc\u30bc\uff09\u3068\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u4ee3\u8b1d<\/strong><\/h3>\n\n\n\n<p><strong>CYP19A1\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u30a2\u30ed\u30de\u30bf\u30fc\u30bc\u3068\u3044\u3046\u9175\u7d20\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001<strong>\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3092\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306b\u5909\u63db<\/strong>\u3059\u308b\u50cd\u304d\u3092\u6301\u3061\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306e\u7523\u751f\u91cf\u304c\u5897\u52a0\u3057\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u4e71\u308c\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CYP19A1\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 \u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u304c\u904e\u5270\u306b\u306a\u308a\u3001\u4e73\u304c\u3093\u30ea\u30b9\u30af\u5897\u52a0<\/li>\n\n\n\n<li><strong>CYP19A1\u306e\u6d3b\u6027\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 \u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u304c\u4e0d\u8db3\u3057\u3001\u9aa8\u5bc6\u5ea6\u4f4e\u4e0b\u3084\u66f4\u5e74\u671f\u75c7\u72b6\u304c\u60aa\u5316<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u578b\u3092\u77e5\u308b\u3053\u3068\u3067\u3001\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u9069\u5207\u306b\u8abf\u6574\u3059\u308b\u305f\u3081\u306e\u98df\u4e8b\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u9078\u629e\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. COMT\u907a\u4f1d\u5b50\u3068\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306e\u5206\u89e3\u80fd\u529b<\/strong><\/h3>\n\n\n\n<p>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u306e\u5206\u89e3\u306b\u306f <strong>COMT\uff08\u30ab\u30c6\u30b3\u30fc\u30eb-O-\u30e1\u30c1\u30eb\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc\uff09<\/strong> \u3068\u3044\u3046\u9175\u7d20\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u9175\u7d20\u306f\u3001\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u3092\u4e0d\u6d3b\u6027\u5316\u3057\u3001\u4f53\u5916\u3078\u6392\u51fa\u3059\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u304c\u3001COMT\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u3068\u5206\u89e3\u80fd\u529b\u306b\u500b\u4eba\u5dee\u304c\u751f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>COMT\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 \u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u304c\u4f53\u5185\u306b\u9577\u304f\u7559\u307e\u308a\u3001\u4e73\u304c\u3093\u3084\u5b50\u5bae\u5185\u819c\u75c7\u306e\u30ea\u30b9\u30af\u5897\u52a0<\/li>\n\n\n\n<li><strong>COMT\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u4eba<\/strong> \u2192 \u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u304c\u65e9\u304f\u5206\u89e3\u3055\u308c\u3001\u66f4\u5e74\u671f\u75c7\u72b6\u304c\u65e9\u304f\u73fe\u308c\u308b<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001COMT\u907a\u4f1d\u5b50\u306e\u30bf\u30a4\u30d7\u3092\u77e5\u308b\u3053\u3068\u3067\u3001\u30db\u30eb\u30e2\u30f3\u88dc\u5145\u7642\u6cd5\uff08HRT\uff09\u306e\u9069\u5fdc\u3084\u98df\u4e8b\u7642\u6cd5\u3092\u3088\u308a\u7cbe\u5bc6\u306b\u8a2d\u8a08\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3057\u305f\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u6700\u9069\u5316<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u98df\u4e8b\u3068\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u3066\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u6804\u990a\u7d20\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u5fc5\u8981\u306a\u6804\u990a\u7d20<\/strong><\/td><td><strong>\u63a8\u5968\u98df\u54c1<\/strong><\/td><\/tr><tr><td>CYP19A1\u5909\u7570<\/td><td>\u6297\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u98df\u54c1<\/td><td>\u30d6\u30ed\u30c3\u30b3\u30ea\u30fc\u3001\u5927\u8c46<\/td><\/tr><tr><td>COMT\u6d3b\u6027\u4f4e\u4e0b<\/td><td>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u4ee3\u8b1d\u4fc3\u9032<\/td><td>\u7dd1\u8336\u3001\u30a6\u30b3\u30f3<\/td><\/tr><tr><td>AR\u611f\u53d7\u6027\u4f4e\u4e0b<\/td><td>\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u5897\u5f37\u98df\u54c1<\/td><td>\u8d64\u8eab\u8089\u3001\u4e9c\u925b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3068\u30db\u30eb\u30e2\u30f3\u8abf\u6574<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CYP19A1\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong> \u2192 \u904e\u5ea6\u306a\u30a2\u30eb\u30b3\u30fc\u30eb\u6442\u53d6\u3092\u63a7\u3048\u3001\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u7523\u751f\u3092\u6291\u5236<\/li>\n\n\n\n<li><strong>COMT\u6d3b\u6027\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 \u9069\u5ea6\u306a\u904b\u52d5\u3092\u53d6\u308a\u5165\u308c\u3001\u30db\u30eb\u30e2\u30f3\u306e\u4ee3\u8b1d\u3092\u4fc3\u9032<\/li>\n\n\n\n<li><strong>AR\u611f\u53d7\u6027\u304c\u4f4e\u3044\u4eba<\/strong> \u2192 \u30a6\u30a7\u30a4\u30c8\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u53d6\u308a\u5165\u308c\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u5206\u6ccc\u3092\u4fc3\u9032<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u95a2\u4fc2\u3092\u6df1\u6398\u308a\u3059\u308b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"724\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/2469831_m-1024x724.jpg\" alt=\"\" class=\"wp-image-5113\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/2469831_m-1024x724.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/2469831_m-300x212.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/2469831_m-768x543.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/2469831_m-1536x1086.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/2469831_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306f\u3001\u79c1\u305f\u3061\u306e\u5065\u5eb7\u3084\u7cbe\u795e\u72b6\u614b\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u907a\u4f1d\u5b50\u304c\u30db\u30eb\u30e2\u30f3\u306e\u7523\u751f\u3084\u5206\u89e3\u306b\u3069\u306e\u3088\u3046\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u306e\u304b\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u3005\u306b\u6700\u9069\u306a\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u3088\u308a\u8a73\u7d30\u306a\u907a\u4f1d\u5b50\u3068\u30db\u30eb\u30e2\u30f3\u306e\u95a2\u4fc2\u3001\u304a\u3088\u3073\u5b9f\u8df5\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3064\u3044\u3066\u6398\u308a\u4e0b\u3052\u307e\u3059\u3002<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u5f79\u5272<\/strong><\/h3>\n\n\n\n<h2 class=\"wp-block-heading\">\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306f\u3001\u57fa\u790e\u4ee3\u8b1d\u3092\u8abf\u7bc0\u3057\u3001\u4f53\u6e29\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u751f\u7523\u3001\u795e\u7d4c\u6a5f\u80fd\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002\u3053\u306e\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u3084\u50cd\u304d\u3082\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u95a2\u9023\u3059\u308b\u4e3b\u8981\u907a\u4f1d\u5b50<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>DIO1\u907a\u4f1d\u5b50\uff08\u8131\u30e8\u30a6\u7d20\u9175\u7d20\uff09<\/strong>\uff1aT4\uff08\u30b5\u30a4\u30ed\u30ad\u30b7\u30f3\uff09\u3092T3\uff08\u30c8\u30ea\u30e8\u30fc\u30c9\u30b5\u30a4\u30ed\u30cb\u30f3\uff09\u306b\u5909\u63db\u3059\u308b\u9175\u7d20\u306e\u907a\u4f1d\u5b50\u3002\u5909\u7570\u304c\u3042\u308b\u3068T3\u3078\u306e\u5909\u63db\u52b9\u7387\u304c\u4f4e\u4e0b\u3057\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u304c\u920d\u5316\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>TSHR\u907a\u4f1d\u5b50\uff08\u7532\u72b6\u817a\u523a\u6fc0\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\uff09<\/strong>\uff1a\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u3092\u8abf\u6574\u3002\u5909\u7570\u306b\u3088\u308a\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u3084\u30d0\u30bb\u30c9\u30a6\u75c5\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30a2\u30d7\u30ed\u30fc\u30c1<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u98df\u4e8b\u3068\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb<\/strong><\/td><\/tr><tr><td>DIO1\u5909\u7570\u3042\u308a<\/td><td>T4\u2192T3\u5909\u63db\u304c\u9045\u3044<\/td><td>\u30e8\u30a6\u7d20\u3092\u591a\u304f\u542b\u3080\u6d77\u85fb\u3001\u4e9c\u925b\u30fb\u30bb\u30ec\u30f3\u306e\u88dc\u7d66<\/td><\/tr><tr><td>TSHR\u5909\u7570\u3042\u308a<\/td><td>\u7532\u72b6\u817a\u6a5f\u80fd\u304c\u4e0d\u5b89\u5b9a<\/td><td>\u30b0\u30eb\u30c6\u30f3\u3092\u63a7\u3048\u3081\u306b\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u3092\u7ba1\u7406<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u3092\u77e5\u308b\u3053\u3068\u3067\u3001\u4ee3\u8b1d\u3092\u6700\u9069\u5316\u3059\u308b\u65b9\u6cd5\u3092\u898b\u3064\u3051\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/h2>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u526f\u814e\u30db\u30eb\u30e2\u30f3\u3068\u30b9\u30c8\u30ec\u30b9\u8010\u6027<\/strong><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">\u526f\u814e\u304b\u3089\u5206\u6ccc\u3055\u308c\u308b\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\uff08\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\uff09\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u53cd\u5fdc\u3084\u514d\u75ab\u6a5f\u80fd\u306e\u8abf\u6574\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u526f\u814e\u30db\u30eb\u30e2\u30f3\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NR3C1\u907a\u4f1d\u5b50\uff08\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\uff09<\/strong>\uff1a\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u3092\u6c7a\u5b9a\u3002\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u30b9\u30c8\u30ec\u30b9\u3078\u306e\u53cd\u5fdc\u304c\u904e\u5270\u307e\u305f\u306f\u920d\u5316\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>HSD11B1\u907a\u4f1d\u5b50\uff08\u30d2\u30c9\u30ed\u30ad\u30b7\u30b9\u30c6\u30ed\u30a4\u30c9\u8131\u6c34\u7d20\u9175\u7d20\uff09<\/strong>\uff1a\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u6d3b\u6027\u5316\u3092\u8abf\u6574\u3002\u5909\u7570\u304c\u3042\u308b\u3068\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u306e\u5206\u89e3\u304c\u9045\u304f\u306a\u308a\u3001\u6162\u6027\u7684\u306a\u30b9\u30c8\u30ec\u30b9\u72b6\u614b\u306b\u9665\u308a\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3092\u9ad8\u3081\u308b\u305f\u3081\u306e\u30a2\u30d7\u30ed\u30fc\u30c1<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u5f71\u97ff<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u6cd5<\/strong><\/td><\/tr><tr><td>NR3C1\u5909\u7570\u3042\u308a<\/td><td>\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u304c\u4f4e\u3044<\/td><td>\u7791\u60f3\u3001\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u88dc\u7d66\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u63a7\u3048\u308b<\/td><\/tr><tr><td>HSD11B1\u5909\u7570\u3042\u308a<\/td><td>\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u5206\u89e3\u304c\u9045\u3044<\/td><td>\u9069\u5ea6\u306a\u904b\u52d5\u3001\u30d3\u30bf\u30df\u30f3C\u6442\u53d6<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u30b9\u30c8\u30ec\u30b9\u306b\u5f31\u3044\u907a\u4f1d\u5b50\u578b\u306e\u4eba\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u8efd\u6e1b\u306e\u305f\u3081\u306e\u751f\u6d3b\u7fd2\u6163\u3092\u610f\u8b58\u3059\u308b\u3053\u3068\u3067\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3092\u5b89\u5b9a\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u3068\u907a\u4f1d\u5b50<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/992550_m-1024x683.jpg\" alt=\"\u4eba\u4f53 \u30d1\u30ba\u30eb\u30d4\u30fc\u30b92\" class=\"wp-image-4774\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/992550_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/992550_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/992550_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/992550_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/992550_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u8840\u7cd6\u5024\u3092\u8abf\u6574\u3059\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308a\u3001\u305d\u306e\u611f\u53d7\u6027\u306f\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>TCF7L2\u907a\u4f1d\u5b50<\/strong>\uff1a\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3092\u8abf\u6574\u3057\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u3092\u5de6\u53f3\u3059\u308b\u3002\u5909\u7570\u304c\u3042\u308b\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u4f4e\u4e0b\u3057\u3001\u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u304c\u4e0a\u6607\u3002<\/li>\n\n\n\n<li><strong>PPARG\u907a\u4f1d\u5b50<\/strong>\uff1a\u8102\u80aa\u7d30\u80de\u306e\u4ee3\u8b1d\u3092\u8abf\u6574\u3057\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002\u5909\u7570\u304c\u3042\u308b\u3068\u8102\u80aa\u71c3\u713c\u304c\u9045\u304f\u306a\u308a\u3001\u4f53\u91cd\u5897\u52a0\u306b\u3064\u306a\u304c\u308a\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u3092\u5411\u4e0a\u3055\u305b\u308b\u65b9\u6cd5<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u98df\u4e8b\u3068\u904b\u52d5<\/strong><\/td><\/tr><tr><td>TCF7L2\u5909\u7570\u3042\u308a<\/td><td>\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u4f4e\u3044<\/td><td>\u4f4eGI\u98df\u54c1\u3001\u98df\u7269\u7e4a\u7dad\u306e\u591a\u3044\u98df\u4e8b<\/td><\/tr><tr><td>PPARG\u5909\u7570\u3042\u308a<\/td><td>\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u304c\u4f4e\u3044<\/td><td>\u6709\u9178\u7d20\u904b\u52d5\u3001\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u306e\u6442\u53d6<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u578b\u306e\u4eba\u306f\u3001\u98df\u4e8b\u3084\u904b\u52d5\u3092\u9069\u5207\u306b\u8abf\u6574\u3059\u308b\u3053\u3068\u3067\u3001\u8840\u7cd6\u5024\u3092\u5b89\u5b9a\u3055\u305b\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u7761\u7720\u30db\u30eb\u30e2\u30f3\uff08\u30e1\u30e9\u30c8\u30cb\u30f3\uff09\u3068\u907a\u4f1d\u5b50<\/strong><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">\u30e1\u30e9\u30c8\u30cb\u30f3\u306f\u3001\u4f53\u5185\u6642\u8a08\u3092\u8abf\u6574\u3057\u3001\u7761\u7720\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3059\u3002\u305d\u306e\u751f\u6210\u3068\u611f\u53d7\u6027\u306b\u3082\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30e1\u30e9\u30c8\u30cb\u30f3\u3068\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MTNR1B\u907a\u4f1d\u5b50\uff08\u30e1\u30e9\u30c8\u30cb\u30f3\u53d7\u5bb9\u4f53\uff09<\/strong>\uff1a\u30e1\u30e9\u30c8\u30cb\u30f3\u306e\u50cd\u304d\u3092\u6c7a\u5b9a\u3057\u3001\u5909\u7570\u304c\u3042\u308b\u3068\u7761\u7720\u306e\u8cea\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3002<\/li>\n\n\n\n<li><strong>CLOCK\u907a\u4f1d\u5b50<\/strong>\uff1a\u4f53\u5185\u6642\u8a08\u306e\u30ea\u30ba\u30e0\u3092\u8abf\u6574\u3002\u5909\u7570\u304c\u3042\u308b\u3068\u6982\u65e5\u30ea\u30ba\u30e0\u304c\u4e71\u308c\u3084\u3059\u304f\u306a\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u7761\u7720\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u65b9\u6cd5<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u7761\u7720\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u5bfe\u7b56<\/strong><\/td><\/tr><tr><td>MTNR1B\u5909\u7570\u3042\u308a<\/td><td>\u30e1\u30e9\u30c8\u30cb\u30f3\u306e\u50cd\u304d\u304c\u5f31\u3044<\/td><td>\u5c31\u5bdd\u524d\u306e\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3092\u907f\u3051\u308b\u3001\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u6442\u53d6<\/td><\/tr><tr><td>CLOCK\u907a\u4f1d\u5b50\u5909\u7570\u3042\u308a<\/td><td>\u4f53\u5185\u6642\u8a08\u304c\u4e71\u308c\u3084\u3059\u3044<\/td><td>\u4e00\u5b9a\u306e\u6642\u9593\u306b\u5bdd\u8d77\u304d\u3059\u308b\u3001\u30e1\u30e9\u30c8\u30cb\u30f3\u30b5\u30d7\u30ea\u306e\u6d3b\u7528<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u907a\u4f1d\u5b50\u578b\u306b\u57fa\u3065\u3044\u305f\u7761\u7720\u6539\u5584\u7b56\u3092\u5b9f\u65bd\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u8cea\u306e\u9ad8\u3044\u4f11\u606f\u3092\u5f97\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/h2>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3057\u305f\u7dcf\u5408\u7684\u306a\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u8abf\u6574<\/strong><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3092\u3088\u308a\u52b9\u679c\u7684\u306b\u7ba1\u7406\u3067\u304d\u307e\u3059\u3002<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u7dcf\u5408\u7684\u30a2\u30d7\u30ed\u30fc\u30c1<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50<\/strong><\/td><td><strong>\u5f71\u97ff<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb<\/strong><\/td><\/tr><tr><td>CYP19A1<\/td><td>\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u904e\u5270<\/td><td>\u5927\u8c46\u88fd\u54c1\u3092\u63a7\u3048\u3081\u306b\u3059\u308b\u3001\u6297\u9178\u5316\u98df\u54c1\u3092\u6442\u53d6<\/td><\/tr><tr><td>NR3C1<\/td><td>\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u4f4e\u4e0b<\/td><td>\u7791\u60f3\u3092\u53d6\u308a\u5165\u308c\u308b\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u3092\u63a7\u3048\u308b<\/td><\/tr><tr><td>CLOCK<\/td><td>\u4f53\u5185\u6642\u8a08\u306e\u4e71\u308c<\/td><td>\u6c7a\u307e\u3063\u305f\u6642\u9593\u306b\u5bdd\u308b\u3001\u30e1\u30e9\u30c8\u30cb\u30f3\u6442\u53d6<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u81ea\u5206\u306e\u907a\u4f1d\u7684\u306a\u7279\u6027\u3092\u77e5\u308a\u3001\u305d\u308c\u306b\u5fdc\u3058\u305f\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3092\u63a1\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u8abf\u6574\u6cd5<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/4752569_m-1024x683.jpg\" alt=\"\u7b11\u9854\u3067\u4f1a\u8a71\u3059\u308b\u5973\u6027\u533b\u5e2b\" class=\"wp-image-4128\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4752569_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4752569_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4752569_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4752569_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4752569_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u4e71\u308c\u306f\u3001\u4f53\u8abf\u4e0d\u826f\u3084\u6162\u6027\u7684\u306a\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u8981\u56e0\u3068\u306a\u308a\u307e\u3059\u3002\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30db\u30eb\u30e2\u30f3\u306e\u50cd\u304d\u3092\u6700\u9069\u5316\u3057\u3001\u500b\u3005\u306e\u4f53\u8cea\u306b\u5408\u3063\u305f\u8abf\u6574\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u907a\u4f1d\u5b50\u5225\u306b\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u308b\u65b9\u6cd5\u306b\u3064\u3044\u3066\u3001\u3088\u308a\u5177\u4f53\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u6210\u9577\u30db\u30eb\u30e2\u30f3\uff08GH\uff09\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306e\u5f79\u5272<\/strong><\/h3>\n\n\n\n<p>\u6210\u9577\u30db\u30eb\u30e2\u30f3\uff08GH\uff09\u306f\u3001\u7b4b\u8089\u306e\u6210\u9577\u3084\u8102\u80aa\u306e\u71c3\u713c\u3001\u7d30\u80de\u306e\u4fee\u5fa9\u3092\u4fc3\u9032\u3059\u308b\u91cd\u8981\u306a\u30db\u30eb\u30e2\u30f3\u3067\u3059\u3002GH\u306e\u5206\u6ccc\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u95a2\u4e0e\u3057\u3001\u907a\u4f1d\u5b50\u578b\u306b\u3088\u3063\u3066\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306e\u7523\u751f\u80fd\u529b\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>GHR\u907a\u4f1d\u5b50\uff08\u6210\u9577\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\uff09<\/strong>\uff1aGH\u306e\u4f5c\u7528\u3092\u6c7a\u5b9a\u3059\u308b\u3002\u5909\u7570\u304c\u3042\u308b\u3068GH\u306e\u52b9\u679c\u304c\u5f31\u307e\u308a\u3001\u7b4b\u8089\u306e\u767a\u9054\u3084\u4ee3\u8b1d\u304c\u4f4e\u4e0b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>IGF1\u907a\u4f1d\u5b50\uff08\u30a4\u30f3\u30b9\u30ea\u30f3\u69d8\u6210\u9577\u56e0\u5b50-1\uff09<\/strong>\uff1aGH\u306e\u50cd\u304d\u3092\u88dc\u52a9\u3057\u3001\u7d30\u80de\u306e\u6210\u9577\u3092\u4fc3\u9032\u3002\u5909\u7570\u306b\u3088\u308aIGF-1\u306e\u611f\u53d7\u6027\u304c\u5909\u5316\u3057\u3001\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306e\u52b9\u679c\u304c\u7570\u306a\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30db\u30eb\u30e2\u30f3\u8abf\u6574\u6cd5<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>GH\u5206\u6ccc\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb<\/strong><\/td><\/tr><tr><td>GHR\u5909\u7570\u3042\u308a<\/td><td>\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306e\u611f\u53d7\u6027\u304c\u4f4e\u3044<\/td><td>\u9ad8\u30bf\u30f3\u30d1\u30af\u98df\u3001\u30a6\u30a7\u30a4\u30c8\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/td><\/tr><tr><td>IGF1\u5909\u7570\u3042\u308a<\/td><td>\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306e\u52b9\u679c\u304c\u4f4e\u4e0b<\/td><td>\u7761\u7720\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u3001\u30a2\u30eb\u30ae\u30cb\u30f3\u6442\u53d6<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>GH\u306f<strong>\u6df1\u3044\u7761\u7720\u4e2d\u306b\u5206\u6ccc\u3055\u308c\u308b<\/strong>\u305f\u3081\u3001\u5c31\u5bdd\u524d\u306e\u30ab\u30d5\u30a7\u30a4\u30f3\u3084\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3092\u907f\u3051\u308b\u3053\u3068\u304c\u91cd\u8981\u3002<\/li>\n\n\n\n<li>**\u30a2\u30eb\u30ae\u30cb\u30f3\u3084\u30aa\u30eb\u30cb\u30c1\u30f3\u3092\u542b\u3080\u98df\u54c1\uff08\u8089\u985e\u3001\u9b5a\u3001\u5927\u8c46\uff09**\u3092\u6442\u53d6\u3059\u308b\u3068GH\u306e\u5206\u6ccc\u304c\u4fc3\u9032\u3055\u308c\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u5973\u6027\u30db\u30eb\u30e2\u30f3\uff08\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\uff09\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u306e\u5f79\u5272<\/strong><\/h3>\n\n\n\n<p>\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u306f\u3001\u6708\u7d4c\u5468\u671f\u306e\u8abf\u6574\u3084\u598a\u5a20\u306e\u7dad\u6301\u3001\u7cbe\u795e\u306e\u5b89\u5b9a\u306b\u95a2\u4e0e\u3059\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3059\u3002\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u3001\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u306e\u5206\u6ccc\u91cf\u3084\u4ee3\u8b1d\u80fd\u529b\u306b\u500b\u4eba\u5dee\u304c\u751f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PGR\u907a\u4f1d\u5b50\uff08\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u53d7\u5bb9\u4f53\uff09<\/strong>\uff1a\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u306e\u611f\u53d7\u6027\u3092\u6c7a\u5b9a\u3002\u5909\u7570\u304c\u3042\u308b\u3068\u30db\u30eb\u30e2\u30f3\u306e\u5f71\u97ff\u3092\u53d7\u3051\u306b\u304f\u304f\u306a\u308a\u3001PMS\uff08\u6708\u7d4c\u524d\u75c7\u5019\u7fa4\uff09\u3084\u4e0d\u598a\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>CYP3A4\u907a\u4f1d\u5b50\uff08\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u4ee3\u8b1d\uff09<\/strong>\uff1a\u809d\u81d3\u3067\u306e\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u5206\u89e3\u3092\u8abf\u6574\u3002\u5909\u7570\u306b\u3088\u308a\u3001\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u304c\u4f53\u5185\u306b\u9577\u304f\u6b8b\u308b\u304b\u3001\u65e9\u304f\u5206\u89e3\u3055\u308c\u308b\u304b\u304c\u6c7a\u307e\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30db\u30eb\u30e2\u30f3\u8abf\u6574\u6cd5<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u5bfe\u7b56<\/strong><\/td><\/tr><tr><td>PGR\u5909\u7570\u3042\u308a<\/td><td>\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u611f\u53d7\u6027\u304c\u4f4e\u3044<\/td><td>\u30d3\u30bf\u30df\u30f3B6\u6442\u53d6\u3001\u30ea\u30e9\u30c3\u30af\u30b9\u7fd2\u6163<\/td><\/tr><tr><td>CYP3A4\u5909\u7570\u3042\u308a<\/td><td>\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u306e\u5206\u89e3\u304c\u65e9\u3044<\/td><td>\u9ad8\u8102\u80aa\u98df\u3092\u63a7\u3048\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3092\u7dad\u6301<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>**\u30d3\u30bf\u30df\u30f3B6\uff08\u30d0\u30ca\u30ca\u3001\u30ca\u30c3\u30c4\u3001\u9d8f\u8089\uff09**\u306f\u3001\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u306e\u50cd\u304d\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>\u30b9\u30c8\u30ec\u30b9\u304c\u30d7\u30ed\u30b2\u30b9\u30c6\u30ed\u30f3\u306e\u5206\u6ccc\u3092\u6291\u5236\u3059\u308b\u305f\u3081\u3001\u7791\u60f3\u3084\u30e8\u30ac\u304c\u6709\u52b9<\/strong>\u3002<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u526f\u814e\u30db\u30eb\u30e2\u30f3\uff08DHEA\uff09\u306e\u5f71\u97ff\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>DHEA\u306e\u5f79\u5272<\/strong><\/h3>\n\n\n\n<p>\u30c7\u30d2\u30c9\u30ed\u30a8\u30d4\u30a2\u30f3\u30c9\u30ed\u30b9\u30c6\u30ed\u30f3\uff08DHEA\uff09\u306f\u3001\u526f\u814e\u3067\u751f\u6210\u3055\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002DHEA\u306e\u5206\u6ccc\u91cf\u306f\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u3001\u52a0\u9f62\u3068\u3068\u3082\u306b\u6e1b\u5c11\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>DHEA\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CYP17A1\u907a\u4f1d\u5b50<\/strong>\uff1aDHEA\u306e\u5408\u6210\u3092\u8abf\u6574\u3002\u5909\u7570\u304c\u3042\u308b\u3068DHEA\u306e\u5206\u6ccc\u91cf\u304c\u4f4e\u4e0b\u3057\u3001\u75b2\u52b4\u611f\u3084\u514d\u75ab\u529b\u306e\u4f4e\u4e0b\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>SULT2A1\u907a\u4f1d\u5b50<\/strong>\uff1aDHEA\u306e\u4ee3\u8b1d\u3092\u8abf\u7bc0\u3002\u5909\u7570\u304c\u3042\u308b\u3068DHEA\u304c\u4f53\u5185\u306b\u9577\u304f\u6b8b\u308b\u304b\u3001\u65e9\u304f\u5206\u89e3\u3055\u308c\u308b\u304b\u304c\u7570\u306a\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30db\u30eb\u30e2\u30f3\u8abf\u6574\u6cd5<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>DHEA\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u751f\u6d3b\u7fd2\u6163<\/strong><\/td><\/tr><tr><td>CYP17A1\u5909\u7570\u3042\u308a<\/td><td>DHEA\u306e\u5206\u6ccc\u304c\u4f4e\u3044<\/td><td>\u9ad8\u305f\u3093\u3071\u304f\u98df\u3001\u5b9a\u671f\u7684\u306a\u904b\u52d5<\/td><\/tr><tr><td>SULT2A1\u5909\u7570\u3042\u308a<\/td><td>DHEA\u306e\u5206\u89e3\u304c\u65e9\u3044<\/td><td>\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u3001\u30aa\u30e1\u30ac3\u6442\u53d6<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9069\u5ea6\u306a\u904b\u52d5\uff08\u6709\u9178\u7d20\uff0b\u7b4b\u30c8\u30ec\uff09\u306fDHEA\u306e\u5206\u6ccc\u3092\u4fc3\u9032\u3059\u308b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\uff08\u30b5\u30fc\u30e2\u30f3\u3001\u304f\u308b\u307f\uff09\u306f\u3001\u526f\u814e\u306e\u5065\u5eb7\u3092\u7dad\u6301\u3057\u3001DHEA\u306e\u751f\u6210\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/01\/23721557_m-1024x683.jpg\" alt=\"\u697d\u3057\u305d\u3046\u306a\u7537\u306e\u5b50\u3068\u5973\u6027\" class=\"wp-image-3229\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23721557_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23721557_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23721557_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23721557_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/01\/23721557_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u306e\u5f79\u5272<\/strong><\/h3>\n\n\n\n<p>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u306f\u300c\u611b\u60c5\u30db\u30eb\u30e2\u30f3\u300d\u3068\u3082\u547c\u3070\u308c\u3001<strong>\u793e\u4f1a\u7684\u306a\u7d46\u306e\u5f62\u6210\u3084\u30b9\u30c8\u30ec\u30b9\u7de9\u548c\u306b\u95a2\u4e0e<\/strong>\u3057\u307e\u3059\u3002\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u3001\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u306e\u5206\u6ccc\u91cf\u3084\u53d7\u5bb9\u4f53\u306e\u611f\u53d7\u6027\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>OXTR\u907a\u4f1d\u5b50\uff08\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u53d7\u5bb9\u4f53\uff09<\/strong>\uff1a\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u306e\u5f71\u97ff\u3092\u53d7\u3051\u308b\u5ea6\u5408\u3044\u3092\u6c7a\u5b9a\u3002\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u4eba\u3068\u306e\u7d46\u3092\u611f\u3058\u306b\u304f\u304f\u306a\u3063\u305f\u308a\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u304c\u4f4e\u4e0b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30db\u30eb\u30e2\u30f3\u8abf\u6574\u6cd5<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u7fd2\u6163<\/strong><\/td><\/tr><tr><td>OXTR\u5909\u7570\u3042\u308a<\/td><td>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u611f\u53d7\u6027\u304c\u4f4e\u3044<\/td><td>\u89aa\u3057\u3044\u4eba\u3068\u306e\u30b9\u30ad\u30f3\u30b7\u30c3\u30d7\u3001\u30a2\u30ed\u30de\u30c6\u30e9\u30d4\u30fc<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30b9\u30ad\u30f3\u30b7\u30c3\u30d7\uff08\u30cf\u30b0\u3001\u30de\u30c3\u30b5\u30fc\u30b8\uff09\u306f\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u5206\u6ccc\u3092\u4fc3\u9032\u3059\u308b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u30e9\u30d9\u30f3\u30c0\u30fc\u3084\u30ab\u30e2\u30df\u30fc\u30eb\u306e\u30a2\u30ed\u30de\u3092\u5229\u7528\u3059\u308b\u3068\u30ea\u30e9\u30c3\u30af\u30b9\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3057\u305f\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u6700\u9069\u5316\u6226\u7565<\/strong><\/h2>\n\n\n\n<p>\u30db\u30eb\u30e2\u30f3\u306f\u79c1\u305f\u3061\u306e\u8eab\u4f53\u306e\u6052\u5e38\u6027\u3092\u7dad\u6301\u3059\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u5206\u6ccc\u3084\u50cd\u304d\u65b9\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u307e\u3059\u3002\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u4e71\u308c\u3092\u4e88\u9632\u3057\u3001\u3088\u308a\u5065\u5eb7\u7684\u306a\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3092\u7bc9\u304f\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30db\u30eb\u30e2\u30f3\u8abf\u6574\u6cd5\u306b\u3064\u3044\u3066\u3001\u3055\u3089\u306b\u8a73\u3057\u304f\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30a4\u30f3\u30b9\u30ea\u30f3\u3068\u4ee3\u8b1d\u306e\u91cd\u8981\u6027<\/strong><\/h3>\n\n\n\n<p>\u30a4\u30f3\u30b9\u30ea\u30f3\u306f\u8840\u7cd6\u5024\u3092\u8abf\u6574\u3059\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308a\u3001\u7cd6\u5c3f\u75c5\u3084\u80a5\u6e80\u306e\u30ea\u30b9\u30af\u3092\u5de6\u53f3\u3059\u308b\u91cd\u8981\u306a\u8981\u7d20\u3067\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u50cd\u304d\u306f\u3001\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u5f37\u304f\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>TCF7L2\u907a\u4f1d\u5b50<\/strong>\uff1a\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u3092\u5236\u5fa1\u3057\u3001\u5909\u7570\u304c\u3042\u308b\u30682\u578b\u7cd6\u5c3f\u75c5\u306e\u30ea\u30b9\u30af\u304c\u4e0a\u6607\u3002<\/li>\n\n\n\n<li><strong>PPARG\u907a\u4f1d\u5b50<\/strong>\uff1a\u8102\u80aa\u7d30\u80de\u306e\u50cd\u304d\u3092\u8abf\u7bc0\u3057\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u3092\u9ad8\u3081\u308b\u3002\u5909\u7570\u304c\u3042\u308b\u3068\u80a5\u6e80\u306e\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u7ba1\u7406\u6226\u7565<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u98df\u4e8b\u30fb\u904b\u52d5<\/strong><\/td><\/tr><tr><td>TCF7L2\u5909\u7570\u3042\u308a<\/td><td>\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u4f4e\u4e0b<\/td><td>\u4f4eGI\u98df\u54c1\u3001\u98df\u7269\u7e4a\u7dad\u3092\u591a\u304f\u6442\u53d6<\/td><\/tr><tr><td>PPARG\u5909\u7570\u3042\u308a<\/td><td>\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u304c\u4f4e\u3044<\/td><td>\u4e2d\u5f37\u5ea6\u306e\u6709\u9178\u7d20\u904b\u52d5\u3001\u30aa\u30e1\u30ac3\u6442\u53d6<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u4f4eGI\u98df\u54c1\uff08\u7384\u7c73\u3001\u91ce\u83dc\u3001\u30ca\u30c3\u30c4\uff09\u3092\u9078\u3076\u3053\u3068\u3067\u8840\u7cd6\u5024\u306e\u6025\u4e0a\u6607\u3092\u9632\u3050<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u9069\u5ea6\u306a\u904b\u52d5\u3092\u7d99\u7d9a\u3059\u308b\u3053\u3068\u3067\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u3092\u5411\u4e0a\u3055\u305b\u3001\u8102\u80aa\u84c4\u7a4d\u3092\u9632\u3050<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u30bb\u30ed\u30c8\u30cb\u30f3\u3068\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u907a\u4f1d\u5b50\u7684\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/22478486_m-1024x683.jpg\" alt=\"\u30d5\u30eb\u30fc\u30c4\u3001\u679c\u7269\u76db\u308a\u5408\u308f\u305b\" class=\"wp-image-4828\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22478486_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22478486_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22478486_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22478486_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/22478486_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30bb\u30ed\u30c8\u30cb\u30f3\u3068\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u5f79\u5272<\/strong><\/h3>\n\n\n\n<p>\u30bb\u30ed\u30c8\u30cb\u30f3\u306f\u5e78\u798f\u611f\u3092\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u306f\u3084\u308b\u6c17\u3084\u5831\u916c\u7cfb\u306e\u5236\u5fa1\u3092\u62c5\u3046\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308a\u3001\u6c17\u5206\u306e\u5b89\u5b9a\u306b\u95a2\u308f\u308b\u91cd\u8981\u306a\u8981\u7d20\u3067\u3059\u3002\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u3001\u3053\u308c\u3089\u306e\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u91cf\u3084\u53d7\u5bb9\u4f53\u306e\u611f\u53d7\u6027\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>5-HTTLPR\uff08\u30bb\u30ed\u30c8\u30cb\u30f3\u8f38\u9001\u4f53\uff09<\/strong>\uff1a\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u5206\u6ccc\u91cf\u3092\u8abf\u6574\u3057\u3001\u5909\u7570\u304c\u3042\u308b\u3068\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u304c\u4f4e\u4e0b\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>COMT\u907a\u4f1d\u5b50<\/strong>\uff1a\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u5206\u89e3\u901f\u5ea6\u3092\u8abf\u7bc0\u3057\u3001\u5909\u7570\u306b\u3088\u308a\u96c6\u4e2d\u529b\u3084\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u7ba1\u7406\u6cd5<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u751f\u6d3b\u7fd2\u6163<\/strong><\/td><\/tr><tr><td>5-HTTLPR\u5909\u7570\u3042\u308a<\/td><td>\u30b9\u30c8\u30ec\u30b9\u306b\u654f\u611f<\/td><td>\u7791\u60f3\u3001\u30ea\u30e9\u30af\u30bc\u30fc\u30b7\u30e7\u30f3\u3001\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u6442\u53d6<\/td><\/tr><tr><td>COMT\u5909\u7570\u3042\u308a<\/td><td>\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u5206\u89e3\u304c\u901f\u3044<\/td><td>\u9ad8\u30ab\u30ab\u30aa\u30c1\u30e7\u30b3\u30ec\u30fc\u30c8\u3001\u904b\u52d5\u3001\u30ab\u30d5\u30a7\u30a4\u30f3\u63a7\u3048\u3081<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30bb\u30ed\u30c8\u30cb\u30f3\u3092\u5897\u3084\u3059\u306b\u306f\u3001\u30d0\u30ca\u30ca\u30fb\u30ca\u30c3\u30c4\u30fb\u9b5a\u306a\u3069\u306e\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u3092\u591a\u304f\u542b\u3080\u98df\u54c1\u3092\u6442\u308b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u7dad\u6301\u306b\u306f\u3001\u9069\u5ea6\u306a\u904b\u52d5\u3092\u7fd2\u6163\u5316\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u3092\u7ba1\u7406\u3059\u308b\u3053\u3068\u304c\u91cd\u8981<\/strong>\u3002<\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u50cd\u304d<\/strong><\/h3>\n\n\n\n<p>\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306f\u4ee3\u8b1d\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u7523\u751f\u306b\u95a2\u4e0e\u3057\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u305d\u306e\u50cd\u304d\u3092\u5de6\u53f3\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7532\u72b6\u817a\u6a5f\u80fd\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>DIO2\u907a\u4f1d\u5b50<\/strong>\uff1aT4\uff08\u30b5\u30a4\u30ed\u30ad\u30b7\u30f3\uff09\u3092T3\uff08\u30c8\u30ea\u30e8\u30fc\u30c9\u30b5\u30a4\u30ed\u30cb\u30f3\uff09\u306b\u5909\u63db\u3059\u308b\u50cd\u304d\u304c\u3042\u308a\u3001\u5909\u7570\u304c\u3042\u308b\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u304c\u4f4e\u4e0b\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>TSHR\u907a\u4f1d\u5b50<\/strong>\uff1a\u7532\u72b6\u817a\u523a\u6fc0\u30db\u30eb\u30e2\u30f3\uff08TSH\uff09\u306e\u611f\u53d7\u6027\u3092\u6c7a\u5b9a\u3057\u3001\u5909\u7570\u304c\u3042\u308b\u3068\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u8abf\u6574\u6cd5<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u98df\u4e8b\u30fb\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb<\/strong><\/td><\/tr><tr><td>DIO2\u5909\u7570\u3042\u308a<\/td><td>T3\u5909\u63db\u304c\u4f4e\u4e0b<\/td><td>\u30e8\u30a6\u7d20\u30fb\u30bb\u30ec\u30f3\u3092\u542b\u3080\u98df\u54c1\u3092\u6442\u53d6<\/td><\/tr><tr><td>TSHR\u5909\u7570\u3042\u308a<\/td><td>\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u30ea\u30b9\u30af<\/td><td>\u30b0\u30eb\u30c6\u30f3\u5236\u9650\u3001\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6d77\u85fb\u985e\uff08\u6606\u5e03\u3001\u308f\u304b\u3081\uff09\u3092\u6442\u53d6\u3057\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u751f\u6210\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u30b9\u30c8\u30ec\u30b9\u304c\u7532\u72b6\u817a\u6a5f\u80fd\u306b\u60aa\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u305f\u3081\u3001\u30ea\u30e9\u30c3\u30af\u30b9\u7fd2\u6163\u3092\u53d6\u308a\u5165\u308c\u308b<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u30e1\u30e9\u30c8\u30cb\u30f3\u3068\u7761\u7720\u306e\u907a\u4f1d\u5b50\u5f71\u97ff<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/31841449_m-1024x683.jpg\" alt=\"\u30d9\u30c3\u30c9\u3067\u3046\u3064\u4f0f\u305b\u3067\u5bdd\u308b\u30a2\u30b8\u30a2\u4eba\u5973\u6027\" class=\"wp-image-4647\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31841449_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31841449_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31841449_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31841449_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31841449_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30e1\u30e9\u30c8\u30cb\u30f3\u3068\u4f53\u5185\u6642\u8a08<\/strong><\/h3>\n\n\n\n<p>\u30e1\u30e9\u30c8\u30cb\u30f3\u306f\u4f53\u5185\u6642\u8a08\u3092\u8abf\u7bc0\u3057\u3001\u7761\u7720\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3059\u3002\u907a\u4f1d\u7684\u306a\u9055\u3044\u306b\u3088\u3063\u3066\u3001\u30e1\u30e9\u30c8\u30cb\u30f3\u306e\u5206\u6ccc\u91cf\u3084\u611f\u53d7\u6027\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MTNR1B\u907a\u4f1d\u5b50<\/strong>\uff1a\u30e1\u30e9\u30c8\u30cb\u30f3\u306e\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3057\u3001\u5909\u7570\u304c\u3042\u308b\u3068\u7761\u7720\u30ea\u30ba\u30e0\u304c\u4e71\u308c\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>CLOCK\u907a\u4f1d\u5b50<\/strong>\uff1a\u6982\u65e5\u30ea\u30ba\u30e0\u3092\u8abf\u7bc0\u3057\u3001\u5909\u7570\u304c\u3042\u308b\u3068\u591c\u66f4\u304b\u3057\u3084\u7761\u7720\u4e0d\u8db3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u578b\u5225\u306e\u7761\u7720\u6539\u5584\u6cd5<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>\u907a\u4f1d\u5b50\u578b<\/strong><\/td><td><strong>\u7761\u7720\u306e\u7279\u5fb4<\/strong><\/td><td><strong>\u63a8\u5968\u3059\u308b\u7fd2\u6163<\/strong><\/td><\/tr><tr><td>MTNR1B\u5909\u7570\u3042\u308a<\/td><td>\u30e1\u30e9\u30c8\u30cb\u30f3\u611f\u53d7\u6027\u304c\u4f4e\u3044<\/td><td>\u591c\u9593\u306e\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3092\u907f\u3051\u308b\u3001\u30e1\u30e9\u30c8\u30cb\u30f3\u88dc\u7d66<\/td><\/tr><tr><td>CLOCK\u5909\u7570\u3042\u308a<\/td><td>\u4f53\u5185\u6642\u8a08\u304c\u4e71\u308c\u3084\u3059\u3044<\/td><td>\u671d\u65e5\u3092\u6d74\u3073\u308b\u3001\u5c31\u5bdd\u6642\u9593\u3092\u56fa\u5b9a\u3059\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>\u30dd\u30a4\u30f3\u30c8<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u591c\u9593\u306e\u30b9\u30de\u30fc\u30c8\u30d5\u30a9\u30f3\u3084PC\u306e\u4f7f\u7528\u3092\u63a7\u3048\u3001\u30e1\u30e9\u30c8\u30cb\u30f3\u306e\u5206\u6ccc\u3092\u4fc3\u3059<\/strong>\u3002<\/li>\n\n\n\n<li><strong>\u671d\u8d77\u304d\u305f\u3089\u65e5\u5149\u3092\u6d74\u3073\u3001\u4f53\u5185\u6642\u8a08\u3092\u30ea\u30bb\u30c3\u30c8\u3059\u308b<\/strong>\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3092\u6d3b\u7528\u3057\u305f\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u306e\u6700\u9069\u5316\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u98df\u4e8b\u3001\u904b\u52d5\u3001\u7761\u7720\u3001\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u3092\u500b\u4eba\u306e\u4f53\u8cea\u306b\u5408\u308f\u305b\u3066\u6700\u9069\u5316\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u306b\u5fdc\u3058\u3066\u7cd6\u8cea\u6442\u53d6\u3092\u8abf\u6574<\/strong><\/li>\n\n\n\n<li><strong>\u30bb\u30ed\u30c8\u30cb\u30f3\u30fb\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u5206\u6ccc\u3092\u4fc3\u9032\u3059\u308b\u98df\u751f\u6d3b\u3092\u53d6\u308a\u5165\u308c\u308b<\/strong><\/li>\n\n\n\n<li><strong>\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u50cd\u304d\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u6804\u990a\u7d20\u3092\u610f\u8b58<\/strong><\/li>\n\n\n\n<li><strong>\u4f53\u5185\u6642\u8a08\u3092\u6574\u3048\u3001\u30e1\u30e9\u30c8\u30cb\u30f3\u306e\u5206\u6ccc\u3092\u4fc3\u9032\u3059\u308b\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3092\u78ba\u7acb<\/strong><\/li>\n<\/ul>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306b\u30db\u30eb\u30e2\u30f3\u30d0\u30e9\u30f3\u30b9\u3092\u8abf\u6574\u3057\u3001\u5065\u5eb7\u7684\u306a\u751f\u6d3b\u3092\u5b9f\u73fe\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h2 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