{"id":8198,"date":"2025-03-05T02:45:50","date_gmt":"2025-03-05T02:45:50","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=8198"},"modified":"2025-04-08T03:40:13","modified_gmt":"2025-04-08T03:40:13","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e6%a4%9c%e6%9f%bb%e7%b5%90%e6%9e%9c%e3%82%92%e3%81%a9%e3%81%86%e8%a7%a3%e9%87%88%e3%81%99%e3%82%8b%ef%bc%9f%e5%b0%82%e9%96%80%e5%ae%b6%e3%81%ae%e5%bd%b9%e5%89%b2","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e6%a4%9c%e6%9f%bb%e7%b5%90%e6%9e%9c%e3%82%92%e3%81%a9%e3%81%86%e8%a7%a3%e9%87%88%e3%81%99%e3%82%8b%ef%bc%9f%e5%b0%82%e9%96%80%e5%ae%b6%e3%81%ae%e5%bd%b9%e5%89%b2\/","title":{"rendered":"\u907a\u4f1d\u5b50\u691c\u67fb\u7d50\u679c\u3092\u3069\u3046\u89e3\u91c8\u3059\u308b\uff1f\u5c02\u9580\u5bb6\u306e\u5f79\u5272"},"content":{"rendered":"\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6280\u8853\u304c\u98db\u8e8d\u7684\u306b\u9032\u6b69\u3057\u3001\u500b\u4eba\u306e\u75be\u60a3\u30ea\u30b9\u30af\u8a55\u4fa1\u3084\u6cbb\u7642\u65b9\u91dd\u306e\u6c7a\u5b9a\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u306f\u975e\u5e38\u306b\u8907\u96d1\u3067\u3042\u308a\u3001\u6b63\u78ba\u306a\u89e3\u91c8\u306b\u306f\u5c02\u9580\u7684\u306a\u77e5\u8b58\u304c\u5fc5\u8981\u3067\u3059\u3002\u9593\u9055\u3063\u305f\u7406\u89e3\u306b\u3088\u3063\u3066\u3001\u4e0d\u5b89\u3092\u611f\u3058\u305f\u308a\u3001\u4e0d\u9069\u5207\u306a\u533b\u7642\u5224\u65ad\u3092\u4e0b\u3057\u305f\u308a\u3059\u308b\u30ea\u30b9\u30af\u3082\u3042\u308b\u305f\u3081\u3001\u5c02\u9580\u5bb6\u306b\u3088\u308b\u9069\u5207\u306a\u30b5\u30dd\u30fc\u30c8\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u672c\u8a18\u4e8b\u3067\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u89e3\u91c8\u3092\u884c\u3046\u4e0a\u3067\u91cd\u8981\u306a\u5c02\u9580\u5bb6\u306e\u5f79\u5272\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3068\u306f\uff1f<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u306f\u3001\u5927\u304d\u304f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u60c5\u5831\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u75be\u60a3\u30ea\u30b9\u30af\u8a55\u4fa1<\/strong>\uff1a\u7279\u5b9a\u306e\u75be\u60a3\u306b\u304b\u304b\u308b\u53ef\u80fd\u6027\u304c\u3069\u306e\u7a0b\u5ea6\u3042\u308b\u304b\u3092\u793a\u3059\u3002<\/li>\n\n\n\n<li><strong>\u85ac\u5264\u5fdc\u7b54\u6027<\/strong>\uff1a\u500b\u3005\u306e\u907a\u4f1d\u7684\u7279\u6027\u306b\u57fa\u3065\u3044\u3066\u3001\u7279\u5b9a\u306e\u85ac\u5264\u304c\u3069\u308c\u307b\u3069\u6709\u52b9\u304b\u3001\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u306f\u3069\u306e\u7a0b\u5ea6\u304b\u3092\u4e88\u6e2c\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>\u907a\u4f1d\u6027\u75be\u60a3\u306e\u8a3a\u65ad<\/strong>\uff1a\u907a\u4f1d\u6027\u75be\u60a3\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3084\u3001\u5bb6\u65cf\u3078\u306e\u5f71\u97ff\u3092\u5224\u65ad\u3059\u308b\u3002<\/li>\n<\/ol>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u304c\u3093\u306e\u907a\u4f1d\u5b50\u30d1\u30cd\u30eb\u691c\u67fb\u3067\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u6cbb\u7642\u6a19\u7684\u3068\u306a\u308b\u304b\u3069\u3046\u304b\u3092\u8a55\u4fa1\u3057\u3001\u6700\u9069\u306a\u6cbb\u7642\u9078\u629e\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5843199\/?utm_source=chatgpt.com\">ncbi.nlm.nih.gov<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u89e3\u91c8\u3059\u308b\u5c02\u9580\u5bb6\u305f\u3061<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 \u81e8\u5e8a\u907a\u4f1d\u5c02\u9580\u533b<\/strong><\/h3>\n\n\n\n<p><strong>\u81e8\u5e8a\u907a\u4f1d\u5c02\u9580\u533b<\/strong>\u306f\u3001\u907a\u4f1d\u6027\u75be\u60a3\u306e\u8a3a\u65ad\u3084\u6cbb\u7642\u306b\u95a2\u3059\u308b\u9ad8\u5ea6\u306a\u77e5\u8b58\u3092\u6301\u3064\u533b\u5e2b\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u304c\u75be\u60a3\u30ea\u30b9\u30af\u306b\u3069\u306e\u3088\u3046\u306b\u95a2\u4fc2\u3059\u308b\u304b\u3092\u8a55\u4fa1\u3059\u308b\u3002<\/li>\n\n\n\n<li>\u5bb6\u65cf\u6b74\u3092\u8003\u616e\u3057\u3001\u907a\u4f1d\u6027\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u7dcf\u5408\u7684\u306b\u5224\u65ad\u3059\u308b\u3002<\/li>\n\n\n\n<li>\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u8ffd\u52a0\u691c\u67fb\u3084\u6cbb\u7642\u306e\u63d0\u6848\u3092\u884c\u3046\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u7279\u306b\u3001\u304c\u3093\u3084\u907a\u4f1d\u6027\u75be\u60a3\u306e\u30ea\u30b9\u30af\u8a55\u4fa1\u306b\u304a\u3044\u3066\u3001\u81e8\u5e8a\u907a\u4f1d\u5c02\u9580\u533b\u306e\u5f79\u5272\u306f\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.mayo.edu\/research\/centers-programs\/medical-genomics-research\/?utm_source=chatgpt.com\">mayo.edu<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2461 \u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30e9\u30fc<\/strong><\/h3>\n\n\n\n<p><strong>\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30e9\u30fc<\/strong>\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u60a3\u8005\u3084\u305d\u306e\u5bb6\u65cf\u306b\u308f\u304b\u308a\u3084\u3059\u304f\u8aac\u660e\u3057\u3001\u9069\u5207\u306a\u610f\u601d\u6c7a\u5b9a\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u5c02\u9580\u8077\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u610f\u7fa9\u3084\u9650\u754c\u3092\u8aac\u660e\u3059\u308b\u3002<\/li>\n\n\n\n<li>\u691c\u67fb\u7d50\u679c\u304c\u3082\u305f\u3089\u3059\u5fc3\u7406\u7684\u5f71\u97ff\u306b\u3064\u3044\u3066\u306e\u76f8\u8ac7\u306b\u4e57\u308b\u3002<\/li>\n\n\n\n<li>\u6cbb\u7642\u3084\u4e88\u9632\u7b56\u306e\u9078\u629e\u80a2\u306b\u3064\u3044\u3066\u60c5\u5831\u63d0\u4f9b\u3092\u884c\u3046\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u7279\u306b\u3001\u51fa\u751f\u524d\u8a3a\u65ad\u3084\u304c\u3093\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u3067\u306f\u3001\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30e9\u30fc\u304c\u60a3\u8005\u306e\u610f\u601d\u6c7a\u5b9a\u3092\u652f\u63f4\u3059\u308b\u5834\u9762\u304c\u591a\u304f\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.nsgc.org\/?utm_source=chatgpt.com\">nsgc.org<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2462 \u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30b7\u30e3\u30f3\uff08\u751f\u7269\u60c5\u5831\u79d1\u5b66\u8005\uff09<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/1246056_m-1024x683.jpg\" alt=\"\u30d1\u30bd\u30b3\u30f3\u3092\u4f7f\u3046\u533b\u5e2b\" class=\"wp-image-8199\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/1246056_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/1246056_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/1246056_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/1246056_m-1536x1025.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/1246056_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30b7\u30e3\u30f3<\/strong>\u306f\u3001\u907a\u4f1d\u5b50\u89e3\u6790\u306e\u305f\u3081\u306e\u81a8\u5927\u306a\u30c7\u30fc\u30bf\u3092\u89e3\u6790\u3057\u3001\u610f\u5473\u306e\u3042\u308b\u60c5\u5831\u3092\u62bd\u51fa\u3059\u308b\u5c02\u9580\u5bb6\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\u306a\u3069\u306e\u907a\u4f1d\u5b50\u89e3\u6790\u30c7\u30fc\u30bf\u3092\u51e6\u7406\u30fb\u89e3\u91c8\u3059\u308b\u3002<\/li>\n\n\n\n<li>\u81e8\u5e8a\u5fdc\u7528\u304c\u53ef\u80fd\u306a\u907a\u4f1d\u5b50\u5909\u7570\u3092\u7279\u5b9a\u3057\u3001\u533b\u7642\u30c1\u30fc\u30e0\u306b\u5831\u544a\u3059\u308b\u3002<\/li>\n\n\n\n<li>\u65b0\u3057\u3044\u907a\u4f1d\u5b50\u5909\u7570\u306e\u7814\u7a76\u3084\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306e\u7ba1\u7406\u3092\u884c\u3046\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u304c\u3093\u30b2\u30ce\u30e0\u533b\u7642\u3084\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30e1\u30c7\u30a3\u30b7\u30f3\u306e\u767a\u5c55\u306b\u4f34\u3044\u3001\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30b7\u30e3\u30f3\u306e\u5f79\u5272\u304c\u307e\u3059\u307e\u3059\u91cd\u8981\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.ebi.ac.uk\/?utm_source=chatgpt.com\">ebi.ac.uk<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u533b\u7642\u73fe\u5834\u3067\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6d3b\u7528<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 \u304c\u3093\u6cbb\u7642\u3068\u907a\u4f1d\u5b50\u691c\u67fb<\/strong><\/h3>\n\n\n\n<p>\u304c\u3093\u30b2\u30ce\u30e0\u533b\u7642\u3067\u306f\u3001\u907a\u4f1d\u5b50\u30d1\u30cd\u30eb\u691c\u67fb\u306b\u3088\u3063\u3066\u60a3\u8005\u306e\u816b\u760d\u306b\u7279\u7570\u7684\u306a\u907a\u4f1d\u5b50\u5909\u7570\u3092\u7279\u5b9a\u3057\u3001\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>BRCA1\/BRCA2\u5909\u7570<\/strong>\uff1a\u4e73\u304c\u3093\u30fb\u5375\u5de3\u304c\u3093\u306e\u30ea\u30b9\u30af\u8a55\u4fa1\u306b\u4f7f\u7528\u3055\u308c\u3001PARP\u963b\u5bb3\u5264\u304c\u6709\u52b9\u3068\u3055\u308c\u308b\u3002<\/li>\n\n\n\n<li><strong>EGFR\u5909\u7570<\/strong>\uff1a\u80ba\u304c\u3093\u306e\u6cbb\u7642\u9078\u629e\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u7279\u5b9a\u306e\u5206\u5b50\u6a19\u7684\u85ac\u304c\u9069\u5fdc\u3068\u306a\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>(<a href=\"https:\/\/www.cancer.gov\/?utm_source=chatgpt.com\">cancer.gov<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2461 \u907a\u4f1d\u5b50\u691c\u67fb\u3068\u85ac\u5264\u9078\u629e\uff08\u30d5\u30a1\u30fc\u30de\u30b3\u30b2\u30ce\u30df\u30af\u30b9\uff09<\/strong><\/h3>\n\n\n\n<p><strong>\u30d5\u30a1\u30fc\u30de\u30b3\u30b2\u30ce\u30df\u30af\u30b9<\/strong>\uff08\u85ac\u7406\u907a\u4f1d\u5b66\uff09\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3057\u3066\u85ac\u5264\u306e\u52b9\u679c\u3084\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u3092\u8a55\u4fa1\u3059\u308b\u5206\u91ce\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CYP2C19\u907a\u4f1d\u5b50<\/strong>\uff1a\u6297\u8840\u5c0f\u677f\u85ac\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u306e\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057\u3001\u4ee3\u8b1d\u80fd\u529b\u304c\u4f4e\u3044\u5834\u5408\u306f\u5225\u306e\u85ac\u5264\u306b\u5909\u66f4\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>SLCO1B1\u907a\u4f1d\u5b50<\/strong>\uff1a\u30b9\u30bf\u30c1\u30f3\uff08\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u4f4e\u4e0b\u85ac\uff09\u306e\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u3092\u4e88\u6e2c\u3059\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u306b\u3088\u308a\u3001\u60a3\u8005\u3054\u3068\u306b\u6700\u9069\u306a\u85ac\u5264\u3092\u9078\u629e\u3057\u3001\u526f\u4f5c\u7528\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.pharmgkb.org\/?utm_source=chatgpt.com\">pharmgkb.org<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u907a\u4f1d\u5b50\u691c\u67fb\u7d50\u679c\u306e\u6b63\u3057\u3044\u7406\u89e3\u306e\u305f\u3081\u306b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/30532351_m-1024x683.jpg\" alt=\"\" class=\"wp-image-7378\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/30532351_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/30532351_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/30532351_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/30532351_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/30532351_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u306f\u3001\u5c02\u9580\u7684\u306a\u77e5\u8b58\u304c\u306a\u3044\u3068\u8aa4\u89e3\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 \u691c\u67fb\u7d50\u679c\u306f\u300c\u78ba\u5b9a\u8a3a\u65ad\u300d\u3067\u306f\u306a\u3044<\/strong><\/h3>\n\n\n\n<p>\u591a\u304f\u306e\u75be\u60a3\u30ea\u30b9\u30af\u8a55\u4fa1\u306f\u300c\u53ef\u80fd\u6027\u300d\u3092\u793a\u3059\u3082\u306e\u3067\u3042\u308a\u3001\u5fc5\u305a\u3057\u3082\u75c5\u6c17\u304c\u767a\u75c7\u3059\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2461 \u907a\u4f1d\u60c5\u5831\u306f\u74b0\u5883\u8981\u56e0\u3068\u7d44\u307f\u5408\u308f\u3055\u3063\u3066\u5f71\u97ff\u3092\u4e0e\u3048\u308b<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306f\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u793a\u3057\u307e\u3059\u304c\u3001\u751f\u6d3b\u7fd2\u6163\u3084\u74b0\u5883\u56e0\u5b50\u3082\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2462 \u533b\u7642\u5c02\u9580\u5bb6\u3068\u76f8\u8ac7\u3057\u306a\u304c\u3089\u6d3b\u7528\u3059\u308b\u3053\u3068\u304c\u91cd\u8981<\/strong><\/h3>\n\n\n\n<p>\u81ea\u5df1\u5224\u65ad\u305b\u305a\u3001\u81e8\u5e8a\u907a\u4f1d\u5c02\u9580\u533b\u3084\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30e9\u30fc\u306e\u6307\u5c0e\u306e\u3082\u3068\u3067\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.cdc.gov\/genomics\/about\/index.htm?utm_source=chatgpt.com\">cdc.gov<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u9650\u754c\u3068\u8ab2\u984c<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7cbe\u5ea6\u3084\u6280\u8853\u306f\u9032\u5316\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u3044\u304f\u3064\u304b\u306e\u91cd\u8981\u306a\u8ab2\u984c\u3082\u5b58\u5728\u3057\u307e\u3059\u3002\u5c02\u9580\u5bb6\u304c\u6b63\u78ba\u306a\u89e3\u91c8\u3092\u884c\u3046\u305f\u3081\u306b\u306f\u3001\u3053\u308c\u3089\u306e\u9650\u754c\u3092\u7406\u89e3\u3057\u3001\u9069\u5207\u306b\u5bfe\u5fdc\u3059\u308b\u3053\u3068\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 \u691c\u67fb\u7d50\u679c\u306e\u4e0d\u78ba\u5b9f\u6027<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u304c\u793a\u3059\u30ea\u30b9\u30af\u306f\u3001\u5fc5\u305a\u3057\u3082\u767a\u75c7\u3092\u610f\u5473\u3059\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u4f8b\u3048\u3070\u3001\u3042\u308b\u75be\u60a3\u306e\u30ea\u30b9\u30af\u304c\u300c\u9ad8\u3044\u300d\u3068\u5224\u5b9a\u3055\u308c\u3066\u3082\u3001\u305d\u308c\u306f\u7d71\u8a08\u7684\u306a\u50be\u5411\u306b\u57fa\u3065\u3044\u305f\u3082\u306e\u3067\u3042\u308a\u3001\u5b9f\u969b\u306b\u767a\u75c7\u3059\u308b\u304b\u3069\u3046\u304b\u306f\u74b0\u5883\u8981\u56e0\u3084\u751f\u6d3b\u7fd2\u6163\u306b\u3082\u5927\u304d\u304f\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>**\u30dd\u30ea\u30b8\u30a7\u30cb\u30c3\u30af\u30ea\u30b9\u30af\u30b9\u30b3\u30a2\uff08PRS\uff09**\u306e\u6d3b\u7528<br>PRS\u306f\u3001\u8907\u6570\u306e\u907a\u4f1d\u7684\u8981\u56e0\u3092\u7d71\u5408\u3057\u3066\u75be\u60a3\u30ea\u30b9\u30af\u3092\u7b97\u51fa\u3059\u308b\u624b\u6cd5\u3067\u3059\u304c\u3001\u305d\u306e\u7cbe\u5ea6\u306f\u307e\u3060\u5b8c\u5168\u3067\u306f\u306a\u304f\u3001\u904e\u4fe1\u3059\u308b\u3053\u3068\u306f\u5371\u967a\u3067\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u5bb6\u65cf\u6b74\u3068\u306e\u6bd4\u8f03<\/strong><strong><br><\/strong> \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u304c\u5bb6\u65cf\u6b74\u3068\u4e00\u81f4\u3057\u306a\u3044\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u5bb6\u65cf\u306b\u304c\u3093\u306e\u767a\u75c7\u8005\u304c\u591a\u3044\u5834\u5408\u3067\u3082\u3001\u907a\u4f1d\u5b50\u5909\u7570\u304c\u898b\u3064\u304b\u3089\u306a\u3044\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u9006\u306b\u3001\u907a\u4f1d\u5b50\u5909\u7570\u304c\u3042\u308b\u304b\u3089\u3068\u3044\u3063\u3066\u3001\u5fc5\u305a\u3057\u3082\u75c5\u6c17\u306b\u306a\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<br><\/li>\n<\/ul>\n\n\n\n<p>(<a href=\"https:\/\/www.nature.com\/articles\/s41576-019-0103-0?utm_source=chatgpt.com\">nature.com<\/a>)<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2461 \u4e88\u6e2c\u53ef\u80fd\u306a\u75be\u60a3\u3068\u4e88\u6e2c\u56f0\u96e3\u306a\u75be\u60a3<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/28020069_m-1024x683.jpg\" alt=\"\n\u982d\u3092\u62b1\u3048\u308b\u533b\u8005\u3000doctor\" class=\"wp-image-8206\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/28020069_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/28020069_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/28020069_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/28020069_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/28020069_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u3059\u3079\u3066\u306e\u75be\u60a3\u304c\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u3063\u3066\u4e88\u6e2c\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>a. \u4e88\u6e2c\u304c\u6bd4\u8f03\u7684\u5bb9\u6613\u306a\u75be\u60a3<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5358\u4e00\u907a\u4f1d\u5b50\u75be\u60a3\uff08\u30e2\u30ce\u30b8\u30a7\u30cb\u30c3\u30af\u75be\u60a3\uff09<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\uff08HTT\u907a\u4f1d\u5b50\u5909\u7570\uff09<\/li>\n\n\n\n<li>\u56a2\u80de\u6027\u7dda\u7dad\u75c7\uff08CFTR\u907a\u4f1d\u5b50\u5909\u7570\uff09<\/li>\n\n\n\n<li>\u5bb6\u65cf\u6027\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\uff08LDLR\u907a\u4f1d\u5b50\u5909\u7570\uff09<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>\u5358\u4e00\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u75be\u60a3\u3092\u5f15\u304d\u8d77\u3053\u3059\u5834\u5408\u3001\u691c\u67fb\u306e\u7cbe\u5ea6\u306f\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>b. \u4e88\u6e2c\u304c\u56f0\u96e3\u306a\u75be\u60a3<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u591a\u56e0\u5b50\u75be\u60a3\uff08\u30dd\u30ea\u30b8\u30a7\u30cb\u30c3\u30af\u75be\u60a3\uff09<\/strong>\n<ul class=\"wp-block-list\">\n<li>2\u578b\u7cd6\u5c3f\u75c5<\/li>\n\n\n\n<li>\u9ad8\u8840\u5727<\/li>\n\n\n\n<li>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5<\/li>\n\n\n\n<li>\u3046\u3064\u75c5<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u75be\u60a3\u306f\u3001\u8907\u6570\u306e\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u8981\u56e0\u304c\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u305f\u3081\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u307f\u3067\u767a\u75c7\u3092\u6b63\u78ba\u306b\u4e88\u6e2c\u3059\u308b\u3053\u3068\u306f\u96e3\u3057\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6402782\/?utm_source=chatgpt.com\">ncbi.nlm.nih.gov<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2462 \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u502b\u7406\u7684\u8ab2\u984c<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306f\u500b\u4eba\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u6a5f\u5bc6\u6027\u306e\u9ad8\u3044\u30c7\u30fc\u30bf\u3067\u3042\u308a\u3001\u305d\u306e\u53d6\u308a\u6271\u3044\u306b\u306f\u614e\u91cd\u306a\u5bfe\u5fdc\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u907a\u4f1d\u5b50\u5dee\u5225\u306e\u30ea\u30b9\u30af<\/strong><strong><br><\/strong> \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u57fa\u306b\u3001\u4fdd\u967a\u52a0\u5165\u3084\u96c7\u7528\u306b\u304a\u3044\u3066\u5dee\u5225\u304c\u884c\u308f\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u90e8\u306e\u56fd\u3067\u306f\u3001\u300c\u907a\u4f1d\u60c5\u5831\u5dee\u5225\u7981\u6b62\u6cd5\uff08GINA\uff09\u300d\u306e\u3088\u3046\u306a\u6cd5\u5f8b\u304c\u5236\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u65e5\u672c\u3067\u306f\u307e\u3060\u6cd5\u6574\u5099\u304c\u5341\u5206\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<br><\/li>\n\n\n\n<li><strong>\u500b\u4eba\u60c5\u5831\u306e\u7ba1\u7406<\/strong><strong><br><\/strong> \u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306f\u30cf\u30c3\u30ad\u30f3\u30b0\u3084\u4e0d\u6b63\u5229\u7528\u306e\u30ea\u30b9\u30af\u304c\u3042\u308b\u305f\u3081\u3001\u53b3\u683c\u306a\u7ba1\u7406\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u4f01\u696d\u306b\u3088\u308b\u30c7\u30fc\u30bf\u306e\u5546\u696d\u5229\u7528\u306b\u3064\u3044\u3066\u3082\u3001\u900f\u660e\u6027\u3092\u78ba\u4fdd\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<br><\/li>\n\n\n\n<li><strong>\u5bb6\u65cf\u3078\u306e\u5f71\u97ff<\/strong><strong><br><\/strong> \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u306f\u3001\u672c\u4eba\u3060\u3051\u3067\u306a\u304f\u5bb6\u65cf\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u907a\u4f1d\u6027\u306e\u304c\u3093\u30ea\u30b9\u30af\u304c\u5224\u660e\u3057\u305f\u5834\u5408\u3001\u5bb6\u65cf\u306b\u3082\u540c\u69d8\u306e\u30ea\u30b9\u30af\u304c\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u691c\u67fb\u7d50\u679c\u3092\u3069\u306e\u3088\u3046\u306b\u5171\u6709\u3059\u308b\u304b\u304c\u554f\u984c\u306b\u306a\u308a\u307e\u3059\u3002<br><\/li>\n<\/ul>\n\n\n\n<p>(<a href=\"https:\/\/www.who.int\/genomics\/policy10\/en\/?utm_source=chatgpt.com\">who.int<\/a>)<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6b63\u3057\u304f\u6d3b\u7528\u3059\u308b\u305f\u3081\u306b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/680460_m-1024x683.jpg\" alt=\"\u63e1\u624b\u3092\u3059\u308b\u5916\u56fd\u4eba\u8001\u4eba\u7537\u6027\u3068\u5916\u56fd\u4eba\u5973\u533b1\" class=\"wp-image-5886\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/680460_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/680460_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/680460_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/680460_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/680460_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u9069\u5207\u306b\u6d3b\u7528\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u6b63\u3057\u3044\u60c5\u5831\u3068\u5c02\u9580\u5bb6\u306e\u30b5\u30dd\u30fc\u30c8\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 \u533b\u7642\u5f93\u4e8b\u8005\u3068\u306e\u9023\u643a<\/strong><\/h3>\n\n\n\n<p>\u533b\u7642\u5f93\u4e8b\u8005\uff08\u533b\u5e2b\u3001\u770b\u8b77\u5e2b\u3001\u85ac\u5264\u5e2b\u306a\u3069\uff09\u3068\u9023\u643a\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u9069\u5207\u306a\u8a3a\u65ad\u30fb\u6cbb\u7642\u306b\u3064\u306a\u3052\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u533b\u5e2b\u306e\u5f79\u5272<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u691c\u67fb\u7d50\u679c\u3092\u3082\u3068\u306b\u3001\u8ffd\u52a0\u691c\u67fb\u306e\u5fc5\u8981\u6027\u3092\u5224\u65ad\u3059\u308b\u3002<\/li>\n\n\n\n<li>\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3084\u4e88\u9632\u7b56\u306b\u3064\u3044\u3066\u52a9\u8a00\u3092\u884c\u3046\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u85ac\u5264\u5e2b\u306e\u5f79\u5272<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u85ac\u5264\u306e\u52b9\u679c\u3084\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u3092\u907a\u4f1d\u5b50\u60c5\u5831\u3068\u7167\u3089\u3057\u5408\u308f\u305b\u3001\u9069\u5207\u306a\u6295\u4e0e\u8a08\u753b\u3092\u7acb\u3066\u308b\u3002<\/li>\n\n\n\n<li>\u4f8b\u3048\u3070\u3001<strong>CYP2C9\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3001\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\uff08\u6297\u51dd\u56fa\u85ac\uff09\u306e\u9069\u5207\u306a\u6295\u4e0e\u91cf\u3092\u8abf\u6574\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2461 \u60a3\u8005\u81ea\u8eab\u306e\u7406\u89e3\u3068\u30ea\u30c6\u30e9\u30b7\u30fc\u5411\u4e0a<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u3092\u6b63\u3057\u304f\u89e3\u91c8\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u60a3\u8005\u81ea\u8eab\u306e\u7406\u89e3\u3082\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30ea\u30b9\u30af\u306e\u610f\u5473\u3092\u6b63\u3057\u304f\u7406\u89e3\u3059\u308b<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u4f8b\u3048\u3070\u3001\u300c50%\u306e\u30ea\u30b9\u30af\u300d\u3068\u805e\u3044\u305f\u5834\u5408\u3001\u591a\u304f\u306e\u4eba\u306f\u300c\u534a\u5206\u306e\u78ba\u7387\u3067\u75c5\u6c17\u306b\u306a\u308b\u300d\u3068\u8003\u3048\u304c\u3061\u3067\u3059\u304c\u3001\u3053\u308c\u306f\u7d71\u8a08\u7684\u306a\u6307\u6a19\u3067\u3042\u308a\u3001\u4ed6\u306e\u8981\u56e0\u3082\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u79d1\u5b66\u7684\u6839\u62e0\u306b\u57fa\u3065\u3044\u305f\u60c5\u5831\u3092\u5f97\u308b<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u4e0a\u306b\u306f\u4e0d\u6b63\u78ba\u306a\u60c5\u5831\u3082\u591a\u3044\u305f\u3081\u3001\u4fe1\u983c\u3067\u304d\u308b\u6a5f\u95a2\uff08\u539a\u751f\u52b4\u50cd\u7701\u3001\u56fd\u7acb\u304c\u3093\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\u306a\u3069\uff09\u306e\u60c5\u5831\u3092\u53c2\u7167\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>(<a href=\"https:\/\/www.cdc.gov\/genomics\/about\/index.htm?utm_source=chatgpt.com\">cdc.gov<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2462 \u4e88\u9632\u533b\u7642\u3068\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30fb\u30e1\u30c7\u30a3\u30b7\u30f3\u3078\u306e\u5fdc\u7528<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u9032\u5316\u306b\u3088\u308a\u3001\u4e88\u9632\u533b\u7642\u3084\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30fb\u30e1\u30c7\u30a3\u30b7\u30f3\uff08\u500b\u5225\u5316\u533b\u7642\uff09\u306e\u5b9f\u73fe\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u751f\u6d3b\u7fd2\u6163\u306e\u6700\u9069\u5316<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u80a5\u6e80\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5834\u5408\u3001\u7cd6\u8cea\u5236\u9650\u3084\u904b\u52d5\u7642\u6cd5\u3092\u7a4d\u6975\u7684\u306b\u53d6\u308a\u5165\u308c\u308b\u3002<\/li>\n\n\n\n<li>\u30a2\u30eb\u30b3\u30fc\u30eb\u4ee3\u8b1d\u80fd\u529b\u304c\u4f4e\u3044\u5834\u5408\u3001\u98f2\u9152\u91cf\u3092\u5236\u9650\u3059\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u65e9\u671f\u767a\u898b\u30fb\u65e9\u671f\u6cbb\u7642<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u907a\u4f1d\u6027\u4e73\u304c\u3093\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5834\u5408\u3001\u5b9a\u671f\u7684\u306a\u691c\u8a3a\u3092\u53d7\u3051\u308b\u3053\u3068\u3067\u65e9\u671f\u767a\u898b\u306b\u3064\u306a\u3052\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>(<a href=\"https:\/\/www.phgfoundation.org\/?utm_source=chatgpt.com\">phgfoundation.org<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u3001\u500b\u4eba\u306e\u5065\u5eb7\u7ba1\u7406\u306b\u304a\u3044\u3066\u975e\u5e38\u306b\u6709\u7528\u306a\u30c4\u30fc\u30eb\u3067\u3059\u304c\u3001\u6b63\u3057\u3044\u89e3\u91c8\u3068\u5c02\u9580\u5bb6\u306e\u30b5\u30dd\u30fc\u30c8\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u691c\u67fb\u7d50\u679c\u3092\u9069\u5207\u306b\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u7cbe\u5ea6\u306e\u9ad8\u3044\u533b\u7642\u304c\u5b9f\u73fe\u3057\u3001\u500b\u3005\u306e\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306b\u5408\u3063\u305f\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6280\u8853\u9769\u65b0\u3068\u4eca\u5f8c\u306e\u5c55\u671b<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-1024x683.jpg\" alt=\"\" class=\"wp-image-6399\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/02\/2184100_m-1.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6280\u8853\u306f\u6025\u901f\u306b\u9032\u5316\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u307e\u3067\u56f0\u96e3\u3060\u3063\u305f\u75be\u60a3\u306e\u4e88\u6e2c\u3084\u6cbb\u7642\u306e\u6700\u9069\u5316\u304c\u53ef\u80fd\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u3001<strong>\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\u3084CRISPR\u6280\u8853<\/strong>\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u3088\u308a\u7cbe\u5bc6\u306a\u907a\u4f1d\u5b50\u89e3\u6790\u304c\u5b9f\u73fe\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 \u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\u3068\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u9032\u5316<\/strong><\/h3>\n\n\n\n<p>\u5f93\u6765\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u3067\u306f\u3001\u4e00\u5ea6\u306b\u89e3\u6790\u3067\u304d\u308b\u907a\u4f1d\u5b50\u306e\u6570\u304c\u9650\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001**\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09**\u6280\u8853\u306e\u767b\u5834\u306b\u3088\u308a\u3001\u4e00\u5ea6\u306b\u6570\u5343\u3001\u6570\u767e\u4e07\u306e\u5869\u57fa\u914d\u5217\u3092\u89e3\u6790\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u7cbe\u5ea6\u3068\u30b9\u30d4\u30fc\u30c9\u304c\u98db\u8e8d\u7684\u306b\u5411\u4e0a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>a. NGS\u306b\u3088\u308b\u304c\u3093\u907a\u4f1d\u5b50\u691c\u67fb<\/strong><\/h4>\n\n\n\n<p>\u304c\u3093\u6cbb\u7642\u306b\u304a\u3044\u3066\u306f\u3001<strong>\u30b3\u30f3\u30d1\u30cb\u30aa\u30f3\u8a3a\u65ad<\/strong>\u3068\u547c\u3070\u308c\u308b\u907a\u4f1d\u5b50\u30d1\u30cd\u30eb\u691c\u67fb\u304c\u5c0e\u5165\u3055\u308c\u3001\u500b\u5225\u5316\u533b\u7642\u306e\u5b9f\u73fe\u306b\u8ca2\u732e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MSI\uff08\u30de\u30a4\u30af\u30ed\u30b5\u30c6\u30e9\u30a4\u30c8\u4e0d\u5b89\u5b9a\u6027\uff09\u89e3\u6790<\/strong>\n<ul class=\"wp-block-list\">\n<li>MSI-H\uff08\u9ad8\u983b\u5ea6\u30de\u30a4\u30af\u30ed\u30b5\u30c6\u30e9\u30a4\u30c8\u4e0d\u5b89\u5b9a\u6027\uff09\u3092\u6301\u3064\u304c\u3093\u306f\u3001\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\uff08PD-1\u963b\u5bb3\u5264\uff09\u304c\u6709\u52b9\u3068\u3055\u308c\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>TMB\uff08\u816b\u760d\u5909\u7570\u8ca0\u8377\uff09\u89e3\u6790<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u816b\u760d\u306b\u3069\u308c\u3060\u3051\u306e\u5909\u7570\u304c\u84c4\u7a4d\u3057\u3066\u3044\u308b\u304b\u3092\u8a55\u4fa1\u3057\u3001\u514d\u75ab\u7642\u6cd5\u306e\u9069\u5fdc\u3092\u5224\u65ad\u3059\u308b\u6307\u6a19\u3068\u306a\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>NGS\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u30011\u56de\u306e\u691c\u67fb\u3067\u6570\u767e\u7a2e\u985e\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u7db2\u7f85\u7684\u306b\u89e3\u6790\u3057\u3001\u6700\u9069\u306a\u6cbb\u7642\u6226\u7565\u3092\u7acb\u3066\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.cancer.gov\/about-cancer\/treatment\/types\/precision-medicine?utm_source=chatgpt.com\">cancer.gov<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>b. NGS\u3068\u907a\u4f1d\u6027\u75be\u60a3\u306e\u8a3a\u65ad<\/strong><\/h4>\n\n\n\n<p>NGS\u306f\u3001\u907a\u4f1d\u6027\u75be\u60a3\u306e\u8a3a\u65ad\u7cbe\u5ea6\u3092\u98db\u8e8d\u7684\u306b\u5411\u4e0a\u3055\u305b\u307e\u3057\u305f\u3002\u4f8b\u3048\u3070\u3001\u5f93\u6765\u306eSanger\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\u3067\u306f\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u500b\u5225\u306b\u89e3\u6790\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3057\u305f\u304c\u3001NGS\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u8907\u6570\u306e\u907a\u4f1d\u5b50\u3092\u540c\u6642\u306b\u89e3\u6790\u3057\u3001\u3088\u308a\u8fc5\u901f\u3067\u6b63\u78ba\u306a\u8a3a\u65ad\u304c\u53ef\u80fd\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u4f8b\uff1a\u7b4b\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u306e\u8a3a\u65ad<\/strong>\n<ul class=\"wp-block-list\">\n<li>DMD\uff08\u30c7\u30e5\u30b7\u30a7\u30f3\u30cc\u578b\u7b4b\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\uff09\u306f\u3001<strong>DMD\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u304c\u3001NGS\u306b\u3088\u308a\u5927\u898f\u6a21\u306a\u907a\u4f1d\u5b50\u6b20\u5931\u3084\u91cd\u8907\u3092\u8fc5\u901f\u306b\u691c\u51fa\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u4f8b\uff1a\u81ea\u9589\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u75c7\uff08ASD\uff09\u306e\u907a\u4f1d\u5b50\u89e3\u6790<\/strong>\n<ul class=\"wp-block-list\">\n<li>ASD\u306b\u95a2\u4e0e\u3059\u308b\u8907\u6570\u306e\u907a\u4f1d\u5b50\uff08SHANK3\u3001NRXN1\u306a\u3069\uff09\u3092\u540c\u6642\u306b\u89e3\u6790\u3057\u3001\u907a\u4f1d\u7684\u8981\u56e0\u3092\u7279\u5b9a\u3059\u308b\u8a66\u307f\u304c\u9032\u884c\u4e2d\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>(<a href=\"https:\/\/www.genomeweb.com\/sequencing\/ngs-genetic-disease-diagnostics?utm_source=chatgpt.com\">genomeweb.com<\/a>)<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2461 CRISPR\u6280\u8853\u3068\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u878d\u5408<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/24471134_m-1024x768.jpg\" alt=\"\u5316\u5b66\u306e\u30a4\u30e1\u30fc\u30b8 - \u8a66\u9a13\u7ba1\" class=\"wp-image-7314\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/24471134_m-1024x768.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/24471134_m-300x225.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/24471134_m-768x576.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/24471134_m-1536x1152.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/24471134_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>CRISPR-Cas9<\/strong>\u306f\u3001DNA\u306e\u7279\u5b9a\u306e\u9818\u57df\u3092\u5207\u65ad\u30fb\u7de8\u96c6\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u753b\u671f\u7684\u306a\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u3067\u3059\u3002\u73fe\u5728\u3001\u3053\u306e\u6280\u8853\u3092\u6d3b\u7528\u3057\u3066\u75be\u60a3\u306e\u8a3a\u65ad\u7cbe\u5ea6\u3092\u5411\u4e0a\u3055\u305b\u308b\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CRISPR\u3092\u6d3b\u7528\u3057\u305f\u304c\u3093\u8a3a\u65ad<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u8840\u6db2\u4e2d\u306e\u5fae\u91cf\u306a\u816b\u760dDNA\u3092\u7279\u7570\u7684\u306b\u691c\u51fa\u3057\u3001\u65e9\u671f\u304c\u3093\u8a3a\u65ad\u3092\u53ef\u80fd\u306b\u3059\u308b\u7814\u7a76\u304c\u9032\u884c\u4e2d\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u611f\u67d3\u75c7\u8a3a\u65ad\u3078\u306e\u5fdc\u7528<\/strong>\n<ul class=\"wp-block-list\">\n<li><strong>CRISPR-Cas12\u3001Cas13<\/strong>\u3092\u7528\u3044\u305f\u611f\u67d3\u75c7\u8a3a\u65ad\u30ad\u30c3\u30c8\uff08SHERLOCK\u6280\u8853\uff09\u306b\u3088\u308a\u3001COVID-19\u3084\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306a\u3069\u306e\u30a6\u30a4\u30eb\u30b9\u611f\u67d3\u3092\u8fc5\u901f\u306b\u691c\u51fa\u3067\u304d\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>CRISPR\u6280\u8853\u304c\u907a\u4f1d\u5b50\u691c\u67fb\u3068\u7d44\u307f\u5408\u308f\u3055\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u8fc5\u901f\u304b\u3064\u7cbe\u5ea6\u306e\u9ad8\u3044\u8a3a\u65ad\u304c\u53ef\u80fd\u306b\u306a\u308a\u3001\u500b\u5225\u5316\u533b\u7642\u306e\u767a\u5c55\u306b\u8ca2\u732e\u3059\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.broadinstitute.org\/research-highlights\/crispr-applications?utm_source=chatgpt.com\">broadinstitute.org<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u907a\u4f1d\u5b50\u691c\u67fb\u306e\u793e\u4f1a\u7684\u5f71\u97ff\u3068\u898f\u5236\u306e\u5fc5\u8981\u6027<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6280\u8853\u304c\u767a\u5c55\u3059\u308b\u4e00\u65b9\u3067\u3001\u305d\u306e\u5229\u7528\u306b\u95a2\u3059\u308b\u793e\u4f1a\u7684\u8ab2\u984c\u3084\u502b\u7406\u7684\u554f\u984c\u3082\u6d6e\u4e0a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 \u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306e\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u3068\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306f\u975e\u5e38\u306b\u6a5f\u5bc6\u6027\u306e\u9ad8\u3044\u30c7\u30fc\u30bf\u3067\u3042\u308a\u3001\u9069\u5207\u306b\u7ba1\u7406\u3055\u308c\u306a\u3051\u308c\u3070\u500b\u4eba\u306e\u30d7\u30e9\u30a4\u30d0\u30b7\u30fc\u304c\u4fb5\u5bb3\u3055\u308c\u308b\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30c7\u30fc\u30bf\u306e\u7b2c\u4e09\u8005\u63d0\u4f9b\u554f\u984c<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u4e00\u90e8\u306e\u907a\u4f1d\u5b50\u691c\u67fb\u4f01\u696d\u306f\u3001\u53ce\u96c6\u3057\u305f\u30c7\u30fc\u30bf\u3092\u88fd\u85ac\u4f01\u696d\u3084\u7814\u7a76\u6a5f\u95a2\u3068\u5171\u6709\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li>\u5229\u7528\u8005\u306e\u540c\u610f\u306a\u3057\u306b\u30c7\u30fc\u30bf\u304c\u63d0\u4f9b\u3055\u308c\u308b\u30b1\u30fc\u30b9\u304c\u554f\u984c\u8996\u3055\u308c\u3066\u304a\u308a\u3001\u3088\u308a\u53b3\u683c\u306a\u898f\u5236\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u30b5\u30a4\u30d0\u30fc\u653b\u6483\u306e\u30ea\u30b9\u30af<\/strong><strong><br><\/strong>\n<ul class=\"wp-block-list\">\n<li>\u907a\u4f1d\u5b50\u30c7\u30fc\u30bf\u306f\u30cf\u30c3\u30ad\u30f3\u30b0\u306e\u6a19\u7684\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u533b\u7642\u6a5f\u95a2\u3084\u4f01\u696d\u306f\u9ad8\u5ea6\u306a\u30bb\u30ad\u30e5\u30ea\u30c6\u30a3\u5bfe\u7b56\u3092\u8b1b\u3058\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>(<a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/human-genome-editing?utm_source=chatgpt.com\">who.int<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2461 \u751f\u547d\u4fdd\u967a\u3084\u96c7\u7528\u306b\u304a\u3051\u308b\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u5229\u7528<\/strong><\/h3>\n\n\n\n<p>\u4e00\u90e8\u306e\u56fd\u3067\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u7d50\u679c\u304c\u751f\u547d\u4fdd\u967a\u306e\u52a0\u5165\u6761\u4ef6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u61f8\u5ff5\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7c73\u56fd\u306eGINA\u6cd5\uff08Genetic Information Nondiscrimination Act\uff09<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u96c7\u7528\u3084\u5065\u5eb7\u4fdd\u967a\u306b\u304a\u3044\u3066\u3001\u907a\u4f1d\u60c5\u5831\u3092\u7406\u7531\u3068\u3057\u305f\u5dee\u5225\u3092\u7981\u6b62\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u65e5\u672c\u306e\u72b6\u6cc1<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u751f\u547d\u4fdd\u967a\u696d\u754c\u3067\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u60c5\u5831\u3092\u4fdd\u967a\u52a0\u5165\u306e\u5224\u65ad\u6750\u6599\u306b\u4f7f\u7528\u3059\u308b\u52d5\u304d\u304c\u898b\u3089\u308c\u308b\u304c\u3001\u898f\u5236\u304c\u5341\u5206\u306b\u6574\u5099\u3055\u308c\u3066\u3044\u306a\u3044\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u306e\u4e0d\u9069\u5207\u306a\u5229\u7528\u3092\u9632\u3050\u305f\u3081\u306b\u3001\u5404\u56fd\u3067\u6cd5\u5f8b\u306e\u6574\u5099\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.congress.gov\/bill\/110th-congress\/senate-bill\/358?utm_source=chatgpt.com\">congress.gov<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u907a\u4f1d\u5b50\u691c\u67fb\u3068\u5e02\u8ca9\u30b5\u30fc\u30d3\u30b9\u306e\u5897\u52a0<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"681\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/30472147_m-1024x681.jpg\" alt=\"\u691c\u4fbf\u5bb9\u5668\u3092\u888b\u306b\u5165\u308c\u308b\u5973\u6027\" class=\"wp-image-3879\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30472147_m-1024x681.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30472147_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30472147_m-768x511.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30472147_m-1536x1022.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30472147_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8fd1\u5e74\u3001DTC\uff08Direct-to-Consumer\uff09\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u6025\u901f\u306b\u666e\u53ca\u3057\u3001\u500b\u4eba\u304c\u533b\u7642\u6a5f\u95a2\u3092\u901a\u3055\u305a\u306b\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 DTC\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u30e1\u30ea\u30c3\u30c8\u3068\u30c7\u30e1\u30ea\u30c3\u30c8<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30e1\u30ea\u30c3\u30c8<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u7c21\u4fbf\u3067\u624b\u8efd\u306b\u5229\u7528\u3067\u304d\u308b\u3002<\/li>\n\n\n\n<li>\u5065\u5eb7\u30ea\u30b9\u30af\u3084\u7956\u5148\u89e3\u6790\u306a\u3069\u3001\u8208\u5473\u6df1\u3044\u60c5\u5831\u3092\u5f97\u3089\u308c\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u30c7\u30e1\u30ea\u30c3\u30c8<\/strong>\n<ul class=\"wp-block-list\">\n<li>\u533b\u7642\u7684\u306a\u8a3a\u65ad\u7cbe\u5ea6\u304c\u4e0d\u5341\u5206\u306a\u3053\u3068\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li>\u7d50\u679c\u306e\u8aa4\u89e3\u306b\u3088\u308b\u4e0d\u5b89\u3084\u8aa4\u3063\u305f\u884c\u52d5\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p>DTC\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6b63\u3057\u304f\u6d3b\u7528\u3059\u308b\u306b\u306f\u3001\u5c02\u9580\u5bb6\u306e\u52a9\u8a00\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.fda.gov\/medical-devices\/dtc-genetic-tests?utm_source=chatgpt.com\">fda.gov<\/a>)<\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u666e\u53ca\u306b\u4f34\u3044\u3001\u79d1\u5b66\u7684\u6839\u62e0\u306b\u57fa\u3065\u3044\u305f\u5229\u7528\u304c\u6c42\u3081\u3089\u308c\u308b\u6642\u4ee3\u304c\u5230\u6765\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u907a\u4f1d\u5b50\u691c\u67fb\u3068\u4e88\u9632\u533b\u7642\u306e\u53ef\u80fd\u6027<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u9032\u5316\u306b\u3088\u308a\u3001\u75be\u60a3\u306e\u65e9\u671f\u767a\u898b\u3060\u3051\u3067\u306a\u304f\u3001\u767a\u75c7\u524d\u306e\u4e88\u9632\u533b\u7642\u306b\u3082\u6d3b\u7528\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u500b\u3005\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u8003\u616e\u3057\u305f\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u3068\u306a\u308a\u3001\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3084\u30bf\u30fc\u30b2\u30c3\u30c8\u3092\u7d5e\u3063\u305f\u4e88\u9632\u7b56\u304c\u5b9f\u8df5\u3057\u3084\u3059\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 \u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u30ea\u30b9\u30af\u8a55\u4fa1\u3068\u4e88\u9632<\/strong><\/h3>\n\n\n\n<p>\u591a\u304f\u306e\u751f\u6d3b\u7fd2\u6163\u75c5\uff08\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8840\u5727\u3001\u5fc3\u75be\u60a3\u306a\u3069\uff09\u306f\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u8981\u56e0\u304c\u7d44\u307f\u5408\u308f\u3055\u3063\u3066\u767a\u75c7\u3057\u307e\u3059\u3002\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u4eba\u306e\u30ea\u30b9\u30af\u3092\u4e8b\u524d\u306b\u628a\u63e1\u3057\u3001\u4e88\u9632\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>a. \u7cd6\u5c3f\u75c5\u30ea\u30b9\u30af\u306e\u8a55\u4fa1<\/strong><\/h4>\n\n\n\n<p>2\u578b\u7cd6\u5c3f\u75c5\u306f\u3001<strong>TCF7L2\u907a\u4f1d\u5b50<\/strong>\u306e\u591a\u578b\u304c\u767a\u75c7\u30ea\u30b9\u30af\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u8abf\u7bc0\u304c\u4e0d\u5341\u5206\u306b\u306a\u308a\u3084\u3059\u3044\u305f\u3081\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5bfe\u7b56\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u70ad\u6c34\u5316\u7269\u306e\u6442\u53d6\u91cf\u3092\u8abf\u6574\u3057\u3001\u8840\u7cd6\u5024\u306e\u6025\u4e0a\u6607\u3092\u9632\u3050\u3002<\/li>\n\n\n\n<li>\u6709\u9178\u7d20\u904b\u52d5\u3068\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u7d44\u307f\u5408\u308f\u305b\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u3092\u5411\u4e0a\u3055\u305b\u308b\u3002<\/li>\n\n\n\n<li>\u5b9a\u671f\u7684\u306a\u8840\u7cd6\u5024\u6e2c\u5b9a\u3092\u884c\u3044\u3001\u65e9\u671f\u767a\u898b\u3068\u7ba1\u7406\u3092\u5fb9\u5e95\u3059\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>(<a href=\"https:\/\/diabetesjournals.org\/care\/article\/33\/3\/675\/28093?utm_source=chatgpt.com\">diabetesjournals.org<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>b. \u5fc3\u75be\u60a3\u30ea\u30b9\u30af\u3068\u907a\u4f1d\u5b50\u691c\u67fb<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/4804027_m-1-1024x683.jpg\" alt=\"\u80f8\u3092\u62bc\u3055\u3048\u3066\u85ac\u3092\u6301\u3064\u7537\u6027\" class=\"wp-image-5968\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4804027_m-1-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4804027_m-1-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4804027_m-1-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4804027_m-1-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/4804027_m-1.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u5fc3\u7b4b\u6897\u585e\u3084\u9ad8\u8840\u5727\u306a\u3069\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u306f\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u5834\u5408\u3001\u767a\u75c7\u524d\u306b\u9069\u5207\u306a\u4e88\u9632\u7b56\u3092\u53d6\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>APOE\u907a\u4f1d\u5b50\u306e\u03b54\u578b<\/strong>\u3092\u6301\u3064\u4eba\u306f\u3001\u9ad8\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u8840\u75c7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u3001\u52d5\u8108\u786c\u5316\u304c\u9032\u884c\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>ACE\u907a\u4f1d\u5b50\u306eD\u30a2\u30ec\u30eb<\/strong>\u306f\u3001\u9ad8\u8840\u5727\u306e\u30ea\u30b9\u30af\u3068\u95a2\u9023\u3057\u3001\u7279\u306b\u5869\u5206\u611f\u53d7\u6027\u304c\u9ad8\u3044\u305f\u3081\u3001\u6e1b\u5869\u304c\u63a8\u5968\u3055\u308c\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3067\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3068\u5224\u660e\u3057\u305f\u5834\u5408\u3001<strong>\u30b9\u30bf\u30c1\u30f3\u3084ACE\u963b\u5bb3\u85ac\u306e\u9069\u5207\u306a\u4f7f\u7528\u3001\u98df\u4e8b\u306e\u898b\u76f4\u3057\u3001\u904b\u52d5\u7fd2\u6163\u306e\u6539\u5584<\/strong>\u306a\u3069\u306e\u5bfe\u7b56\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.ahajournals.org\/journal\/circgenetics?utm_source=chatgpt.com\">ahajournals.org<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2461 \u907a\u4f1d\u5b50\u691c\u67fb\u3068\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0<\/strong><\/h3>\n\n\n\n<p>\u8001\u5316\u306e\u30d7\u30ed\u30bb\u30b9\u3082\u907a\u4f1d\u7684\u8981\u56e0\u3068\u5bc6\u63a5\u306b\u95a2\u9023\u3057\u3066\u304a\u308a\u3001\u9069\u5207\u306a\u4ecb\u5165\u306b\u3088\u3063\u3066\u5065\u5eb7\u5bff\u547d\u3092\u5ef6\u3070\u3059\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>a. \u30c6\u30ed\u30e1\u30a2\u306e\u9577\u3055\u3068\u8001\u5316\u30ea\u30b9\u30af<\/strong><\/h4>\n\n\n\n<p>\u30c6\u30ed\u30e1\u30a2\u306f\u67d3\u8272\u4f53\u306e\u672b\u7aef\u306b\u5b58\u5728\u3057\u3001\u7d30\u80de\u306e\u5bff\u547d\u3092\u6c7a\u5b9a\u3059\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002<strong>TERT\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u306f\u3001\u30c6\u30ed\u30e1\u30a2\u306e\u77ed\u7e2e\u901f\u5ea6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u52a0\u9f62\u306b\u4f34\u3046\u75be\u60a3\uff08\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306a\u3069\uff09\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30c6\u30ed\u30e1\u30a2\u306e\u7dad\u6301\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u305f\u3081\u306b\u3001\u4ee5\u4e0b\u306e\u5bfe\u7b56\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>**\u6297\u9178\u5316\u98df\u54c1\uff08\u30d3\u30bf\u30df\u30f3C\u3001E\u3001\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\uff09**\u306e\u7a4d\u6975\u7684\u306a\u6442\u53d6\u3002<\/li>\n\n\n\n<li>**\u9069\u5ea6\u306a\u904b\u52d5\uff08\u7279\u306b\u6709\u9178\u7d20\u904b\u52d5\uff09**\u306b\u3088\u308b\u7d30\u80de\u306e\u4fee\u5fa9\u4fc3\u9032\u3002<\/li>\n\n\n\n<li>**\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\uff08\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u3001\u7791\u60f3\uff09**\u306b\u3088\u308b\u6162\u6027\u7684\u306a\u708e\u75c7\u306e\u6291\u5236\u3002<\/li>\n<\/ul>\n\n\n\n<p>(<a href=\"https:\/\/www.cell.com\/fulltext\/S0092-8674(15)00051-4?utm_source=chatgpt.com\">cell.com<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>b. \u30b5\u30fc\u30c1\u30e5\u30a4\u30f3\u907a\u4f1d\u5b50\u3068\u9577\u5bff<\/strong><\/h4>\n\n\n\n<p><strong>SIRT1\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u7d30\u80de\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3084DNA\u4fee\u5fa9\u306b\u95a2\u4e0e\u3057\u3001\u8001\u5316\u306e\u9032\u884c\u3092\u6291\u5236\u3059\u308b\u5f79\u5272\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002SIRT1\u306e\u6d3b\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u3067\u3001\u5065\u5eb7\u5bff\u547d\u306e\u5ef6\u4f38\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>**\u30ec\u30b9\u30d9\u30e9\u30c8\u30ed\u30fc\u30eb\uff08\u8d64\u30ef\u30a4\u30f3\u3001\u30d6\u30c9\u30a6\uff09**\u304cSIRT1\u3092\u6d3b\u6027\u5316\u3057\u3001\u6297\u8001\u5316\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u3002<\/li>\n\n\n\n<li>**\u30ab\u30ed\u30ea\u30fc\u5236\u9650\uff08CR\uff09**\u304cSIRT1\u306e\u767a\u73fe\u3092\u4fc3\u9032\u3057\u3001\u4ee3\u8b1d\u6a5f\u80fd\u3092\u5411\u4e0a\u3055\u305b\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u77e5\u898b\u3092\u57fa\u306b\u3001\u907a\u4f1d\u7684\u306a\u8001\u5316\u30ea\u30b9\u30af\u3092\u8a55\u4fa1\u3057\u3001\u751f\u6d3b\u7fd2\u6163\u3092\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.nature.com\/articles\/nrm4042?utm_source=chatgpt.com\">nature.com<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. \u907a\u4f1d\u5b50\u691c\u67fb\u3068\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"643\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/29875332_m-1024x643.jpg\" alt=\"\u56f0\u308a\u9854\u306e\u5973\u6027\" class=\"wp-image-5894\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/29875332_m-1024x643.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/29875332_m-300x188.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/29875332_m-768x482.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/29875332_m-1536x965.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/29875332_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u7cbe\u795e\u75be\u60a3\u306b\u3082\u907a\u4f1d\u7684\u8981\u56e0\u304c\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304a\u308a\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306e\u7ba1\u7406\u304c\u3088\u308a\u79d1\u5b66\u7684\u306b\u884c\u3048\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2460 \u3046\u3064\u75c5\u306e\u30ea\u30b9\u30af\u8a55\u4fa1<\/strong><\/h3>\n\n\n\n<p>\u3046\u3064\u75c5\u306f\u3001**SLC6A4\uff08\u30bb\u30ed\u30c8\u30cb\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u907a\u4f1d\u5b50\uff09<strong>\u3084<\/strong>BDNF\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09**\u306e\u5909\u7570\u3068\u95a2\u9023\u304c\u3042\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>**SLC6A4\u306e\u77ed\u7e2e\u578b\uff08S\u578b\uff09**\u3092\u6301\u3064\u4eba\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u3078\u306e\u611f\u53d7\u6027\u304c\u9ad8\u304f\u3001\u3046\u3064\u75c5\u306e\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n\n\n\n<li><strong>BDNF\u306eVal66Met\u591a\u578b<\/strong>\u306f\u3001\u795e\u7d4c\u53ef\u5851\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u9069\u5fdc\u80fd\u529b\u306b\u5dee\u3092\u751f\u3058\u3055\u305b\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3001<strong>\u8a8d\u77e5\u884c\u52d5\u7642\u6cd5\uff08CBT\uff09\u3001\u904b\u52d5\u7642\u6cd5\u3001\u6297\u3046\u3064\u85ac\u306e\u6700\u9069\u5316<\/strong>\u306a\u3069\u306e\u4ecb\u5165\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/211069?utm_source=chatgpt.com\">jamanetwork.com<\/a>)<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u2461 \u907a\u4f1d\u5b50\u691c\u67fb\u3068\u30b9\u30c8\u30ec\u30b9\u8010\u6027<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u306b\u306f\u3001**NR3C1\u907a\u4f1d\u5b50\uff08\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\uff09**\u304c\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u3068\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\uff08\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\uff09\u306e\u8abf\u7bc0\u304c\u3046\u307e\u304f\u6a5f\u80fd\u3057\u306a\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NR3C1\u306e\u7279\u5b9a\u306e\u5909\u7570\u3092\u6301\u3064\u4eba<\/strong>\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u304c\u4f4e\u304f\u3001\u6162\u6027\u7684\u306a\u4e0d\u5b89\u3092\u62b1\u3048\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u53d7\u5bb9\u4f53\uff08OXTR\uff09\u306e\u907a\u4f1d\u5b50\u5909\u7570<\/strong>\u3082\u3001\u5bfe\u4eba\u95a2\u4fc2\u306e\u30b9\u30c8\u30ec\u30b9\u53cd\u5fdc\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u60c5\u5831\u3092\u57fa\u306b\u3001\u500b\u5225\u5316\u3055\u308c\u305f\u30b9\u30c8\u30ec\u30b9\u30de\u30cd\u30b8\u30e1\u30f3\u30c8\u6cd5\u3092\u63d0\u6848\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>(<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S030645301500293X?utm_source=chatgpt.com\">sciencedirect.com<\/a>)<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u5fdc\u7528\u7bc4\u56f2\u306f\u3001\u75be\u60a3\u306e\u4e88\u6e2c\u3060\u3051\u3067\u306a\u304f\u3001\u4e88\u9632\u533b\u7642\u3084\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u30b1\u30a2\u3001\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u306b\u307e\u3067\u5e83\u304c\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u304b\u3089\u306e\u533b\u7642\u306f\u3001\u907a\u4f1d\u60c5\u5831\u3092\u57fa\u306b\u3057\u305f\u500b\u5225\u5316\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u3055\u3089\u306b\u9032\u5316\u3057\u3001\u3088\u308a\u7cbe\u5bc6\u306a\u5065\u5eb7\u7ba1\u7406\u304c\u53ef\u80fd\u306b\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306f<strong>\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9<\/strong>\u3084<strong>\u6804\u990a\u6442\u53d6\u306e\u6700\u9069\u5316<\/strong>\u306b\u3082\u5fdc\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>ACTN3\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u306b\u3088\u308a\u7b4b\u8089\u306e\u7279\u6027\u304c\u7570\u306a\u308a\u3001\u6301\u4e45\u529b\u578b\u304b\u77ac\u767a\u529b\u578b\u304b\u304c\u6c7a\u307e\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-0f238951-7fff-bfed-fa69-05c4e66f8dbb\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> 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