{"id":9584,"date":"2025-03-12T03:11:37","date_gmt":"2025-03-12T03:11:37","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=9584"},"modified":"2025-03-12T03:11:38","modified_gmt":"2025-03-12T03:11:38","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e4%bd%93%e5%8a%9b%e3%81%ae%e9%81%95%e3%81%84%ef%bc%9a%e6%8c%81%e4%b9%85%e5%8a%9b%e3%81%a8%e7%ad%8b%e5%8a%9b%e3%81%ae%e7%a7%98%e5%af%86","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e4%bd%93%e5%8a%9b%e3%81%ae%e9%81%95%e3%81%84%ef%bc%9a%e6%8c%81%e4%b9%85%e5%8a%9b%e3%81%a8%e7%ad%8b%e5%8a%9b%e3%81%ae%e7%a7%98%e5%af%86\/","title":{"rendered":"\u907a\u4f1d\u5b50\u3068\u4f53\u529b\u306e\u9055\u3044\uff1a\u6301\u4e45\u529b\u3068\u7b4b\u529b\u306e\u79d8\u5bc6\u200b"},"content":{"rendered":"\n<p>\u4eba\u9593\u306e\u4f53\u529b\u3001\u7279\u306b\u6301\u4e45\u529b\u3068\u7b4b\u529b\u306e\u5dee\u7570\u306f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u7684\u8981\u56e0\u306e\u8907\u96d1\u306a\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u5f62\u6210\u3055\u308c\u307e\u3059\u3002\u200b\u8fd1\u5e74\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u591a\u578b\u304c\u3053\u308c\u3089\u306e\u4f53\u529b\u7279\u6027\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u200b\u672c\u8a18\u4e8b\u3067\u306f\u3001\u6301\u4e45\u529b\u3068\u7b4b\u529b\u306b\u95a2\u9023\u3059\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50\u3068\u305d\u306e\u5f71\u97ff\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002\u200b<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-da223aa5-7fff-3857-51f9-3bb789d46f76\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u7684\u8981\u56e0\u3068\u4f53\u529b\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u53cc\u5b50\u3084\u5bb6\u65cf\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u306b\u3088\u308a\u3001\u6301\u4e45\u529b\u3084\u7b4b\u529b\u3068\u3044\u3063\u305f\u8eab\u4f53\u80fd\u529b\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u200b\u4f8b\u3048\u3070\u3001\u6700\u5927\u9178\u7d20\u6442\u53d6\u91cf\uff08VO\u2082max\uff09\u306e\u907a\u4f1d\u7387\u306f\u7d0456\uff05\u3001\u7b4b\u529b\u306e\u907a\u4f1d\u7387\u306f\u7d0452\uff05\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u200b<a href=\"https:\/\/www.e-healthnet.mhlw.go.jp\/information\/exercise\/s-03-003.html\">e-\u30d8\u30eb\u30b9\u30cd\u30c3\u30c8+1research-center.juntendo.ac.jp+1<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>ACTN3\u907a\u4f1d\u5b50\u3068\u7b4b\u529b<\/strong><\/h3>\n\n\n\n<p><strong>ACTN3\uff08\u03b1-\u30a2\u30af\u30c1\u30cb\u30f33\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u901f\u7b4b\u7dda\u7dad\u306e\u69cb\u9020\u7dad\u6301\u306b\u95a2\u4e0e\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u200b\u3053\u306e\u907a\u4f1d\u5b50\u306b\u306f\u3001RR\u578b\u3001RX\u578b\u3001XX\u578b\u306e3\u3064\u306e\u591a\u578b\u304c\u5b58\u5728\u3057\u3001\u305d\u308c\u305e\u308c\u7b4b\u529b\u7279\u6027\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002\u200b\u7279\u306b\u3001RR\u578b\u3068RX\u578b\u3092\u6301\u3064\u4eba\u306f\u77ac\u767a\u7cfb\u306e\u80fd\u529b\u306b\u512a\u308c\u3001\u77ed\u8ddd\u96e2\u8d70\u306a\u3069\u306e\u7af6\u6280\u3067\u9ad8\u3044\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u767a\u63ee\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u200b<a href=\"https:\/\/www.rinspo.jp\/journal\/2020\/files\/28-2\/250-251.pdf\">\u9806\u5929\u5802\u5927\u5b66\u5065\u5eb7\u79d1\u5b66\u30bb\u30f3\u30bf\u30fc+3rinspo.jp+3ginza-yobo.clinic+3<\/a><a href=\"https:\/\/research-center.juntendo.ac.jp\/hss\/column\/%E4%BD%93%E5%8A%9B%E7%89%B9%E6%80%A7%E3%81%AE%E5%80%8B%E4%BA%BA%E5%B7%AE%E3%82%92%E7%94%9F%E3%81%BF%E5%87%BA%E3%81%99%E8%A6%81%E5%9B%A0%E3%81%AF%E4%BD%95%E3%81%8B%EF%BC%9F%E3%80%80%E3%80%80%E3%80%80\/\">rinspo.jp+2research-center.juntendo.ac.jp+2\u9806\u5929\u5802\u5927\u5b66\u5065\u5eb7\u79d1\u5b66\u30bb\u30f3\u30bf\u30fc+2<\/a><a href=\"https:\/\/goodhealth.juntendo.ac.jp\/sports\/000034.html\">\u9806\u5929\u5802\u5927\u5b66\u5065\u5eb7\u79d1\u5b66\u30bb\u30f3\u30bf\u30fc<\/a><\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c1c75850-7fff-687c-4b21-f5ae352707b1\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>ACE\u907a\u4f1d\u5b50\u3068\u6301\u4e45\u529b<\/strong><\/h3>\n\n\n\n<p><strong>ACE\uff08\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u5909\u63db\u9175\u7d20\uff09\u907a\u4f1d\u5b50<\/strong>\u306e\u633f\u5165\/\u6b20\u5931\uff08I\/D\uff09\u591a\u578b\u3082\u3001\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u200b\u6b27\u7c73\u4eba\u306e\u30a2\u30b9\u30ea\u30fc\u30c8\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u306f\u3001I\u30a2\u30ec\u30eb\u306f\u6301\u4e45\u7cfb\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3001D\u30a2\u30ec\u30eb\u306f\u77ac\u767a\u7cfb\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3068\u95a2\u9023\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u200b<a href=\"https:\/\/www.rinspo.jp\/journal\/2020\/files\/28-2\/250-251.pdf\">rinspo.jp<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>PPAR\u03b4\u907a\u4f1d\u5b50\u3068\u6301\u4e45\u529b<\/strong><\/h3>\n\n\n\n<p><strong>PPAR\u03b4\uff08\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u5897\u6b96\u56e0\u5b50\u6d3b\u6027\u5316\u53d7\u5bb9\u4f53\u30c7\u30eb\u30bf\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u8102\u8cea\u4ee3\u8b1d\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u200b\u30de\u30a6\u30b9\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u306f\u3001PPAR\u03b4\u306e\u767a\u73fe\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u6301\u4e45\u529b\u304c\u5411\u4e0a\u3057\u3001\u901a\u5e38\u306e2\u500d\u306e\u8ddd\u96e2\u3092\u8d70\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u200b<a href=\"https:\/\/wired.jp\/2004\/08\/25\/%E9%81%BA%E4%BC%9D%E5%AD%90%E6%93%8D%E4%BD%9C%E3%81%A7%E7%AD%8B%E5%8A%9B%E5%A2%97%E5%BC%B7%E2%80%95%E2%80%95%E9%80%9A%E5%B8%B8%E3%81%AE2%E5%80%8D%E3%81%AE%E8%B7%9D%E9%9B%A2%E3%82%92%E8%B5%B0%E3%82%8A\/\">wired.jp<\/a><\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c1c75850-7fff-687c-4b21-f5ae352707b1\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u3068\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u4eba\u306b\u9069\u3057\u305f\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3084\u30b9\u30dd\u30fc\u30c4\u7a2e\u76ee\u306e\u9078\u629e\u304c\u53ef\u80fd\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u200b\u4f8b\u3048\u3070\u3001ACTN3\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306b\u57fa\u3065\u3044\u3066\u3001\u77ac\u767a\u529b\u3092\u8981\u3059\u308b\u7af6\u6280\u3084\u6301\u4e45\u529b\u3092\u8981\u3059\u308b\u7af6\u6280\u3078\u306e\u9069\u6027\u3092\u8a55\u4fa1\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 \u200b<a href=\"https:\/\/www.e-healthnet.mhlw.go.jp\/information\/exercise\/s-03-003.html\">e-\u30d8\u30eb\u30b9\u30cd\u30c3\u30c8<\/a><a href=\"https:\/\/ginza-yobo.clinic\/column\/260\">ginza-yobo.clinic<\/a><\/p>\n\n\n\n<p>\u4ee5\u4e0a\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u3068\u4f53\u529b\u306e\u95a2\u4fc2\u6027\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u4eba\u306e\u7279\u6027\u306b\u5408\u308f\u305b\u305f\u52b9\u679c\u7684\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u7af6\u6280\u9078\u629e\u304c\u53ef\u80fd\u3068\u306a\u308a\u3001\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306e\u5411\u4e0a\u306b\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u200b<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u50cd\u304d<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u529b\u306b\u512a\u308c\u305f\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u7b4b\u8089\u5185\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u304c\u52b9\u7387\u3088\u304f\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u751f\u7523\u3059\u308b\u80fd\u529b\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u80fd\u529b\u306b\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\uff08mtDNA\uff09\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u7684\u8981\u56e0\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>mtDNA\u306e\u591a\u578b\u3068\u6301\u4e45\u529b<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/39699_m-1024x683.jpg\" alt=\"\" class=\"wp-image-9056\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/39699_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/39699_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/39699_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/39699_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/39699_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306fATP\uff08\u30a2\u30c7\u30ce\u30b7\u30f3\u4e09\u30ea\u30f3\u9178\uff09\u3092\u751f\u7523\u3059\u308b\u7d30\u80de\u5c0f\u5668\u5b98\u3067\u3042\u308a\u3001\u305d\u306e\u6a5f\u80fd\u306f\u6301\u4e45\u529b\u306b\u76f4\u63a5\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002\u7279\u5b9a\u306emtDNA\u306e\u591a\u578b\u3092\u6301\u3064\u4eba\u306f\u3001ATP\u3092\u52b9\u7387\u3088\u304f\u751f\u6210\u3057\u3001\u9178\u7d20\u6d88\u8cbb\u52b9\u7387\u304c\u5411\u4e0a\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u6301\u4e45\u529b\u306b\u512a\u308c\u305f\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u591a\u304f\u306f\u3001mtDNA\u306e\u7279\u5b9a\u306e\u30cf\u30d7\u30ed\u30b0\u30eb\u30fc\u30d7\uff08\u907a\u4f1d\u7684\u7cfb\u7d71\uff09\u3092\u6301\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08journals.physiology.org\uff09\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001mtDNA\u306e\u5909\u7570\u306f\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4f9b\u7d66\u306e\u52b9\u7387\u6027\u3060\u3051\u3067\u306a\u304f\u3001\u75b2\u52b4\u8010\u6027\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u5f37\u3044\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u6301\u3064\u4eba\u306f\u3001\u9577\u6642\u9593\u306e\u904b\u52d5\u3067\u3082\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u6301\u7d9a\u7684\u306b\u4f9b\u7d66\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>NRF1\u907a\u4f1d\u5b50\u3068\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u751f\u5408\u6210<\/strong><\/h4>\n\n\n\n<p><strong>NRF1\uff08\u6838\u547c\u5438\u56e0\u5b501\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u751f\u5408\u6210\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u3067\u3042\u308a\u3001\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u5bfe\u3059\u308b\u9069\u5fdc\u3092\u8abf\u7bc0\u3057\u307e\u3059\u3002NRF1\u306e\u6d3b\u6027\u304c\u9ad8\u3044\u4eba\u306f\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u7d99\u7d9a\u3059\u308b\u3053\u3068\u3067\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6570\u304c\u5897\u52a0\u3057\u3001\u6301\u4e45\u529b\u304c\u5411\u4e0a\u3057\u3084\u3059\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211124720313469\">sciencedirect.com<\/a>\uff09\u3002<\/p>\n\n\n\n<p>NRF1\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u306f\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u98df\u4e8b\u306b\u3088\u3063\u3066\u3082\u5909\u5316\u3059\u308b\u305f\u3081\u3001\u9069\u5207\u306a\u6804\u990a\u6226\u7565\uff08\u4f8b\uff1a\u6297\u9178\u5316\u98df\u54c1\u306e\u6442\u53d6\uff09\u3084\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u7a2e\u985e\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u6301\u4e45\u529b\u306e\u5411\u4e0a\u3092\u6700\u5927\u5316\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7b4b\u7dda\u7dad\u306e\u69cb\u6210\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u4f53\u529b\u7279\u6027\u306b\u306f\u3001\u7b4b\u7dda\u7dad\u306e\u69cb\u6210\u3082\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u7b4b\u7dda\u7dad\u306b\u306f\u4e3b\u306b\u901f\u7b4b\uff08Type II\uff09\u3068\u9045\u7b4b\uff08Type I\uff09\u304c\u3042\u308a\u3001\u305d\u308c\u305e\u308c\u304c\u7570\u306a\u308b\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u5236\u5fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>MSTN\u907a\u4f1d\u5b50\u3068\u7b4b\u80a5\u5927<\/strong><\/h4>\n\n\n\n<p><strong>MSTN\uff08\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u7b4b\u8089\u306e\u6210\u9577\u3092\u6291\u5236\u3059\u308b\u5f79\u5272\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u30df\u30aa\u30b9\u30bf\u30c1\u30f3\u306e\u50cd\u304d\u304c\u6291\u3048\u3089\u308c\u3001\u7b4b\u8089\u304c\u901a\u5e38\u3088\u308a\u3082\u767a\u9054\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u5b9f\u969b\u3001MSTN\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u6301\u3064\u4eba\u306f\u3001\u7b4b\u529b\u7cfb\u7af6\u6280\u306b\u304a\u3044\u3066\u512a\u308c\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u767a\u63ee\u3057\u3084\u3059\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5568959\/\">ncbi.nlm.nih.gov<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u52d5\u7269\u5b9f\u9a13\u3067\u306f\u3001MSTN\u907a\u4f1d\u5b50\u304c\u6b20\u640d\u3057\u3066\u3044\u308b\u30de\u30a6\u30b9\u306f\u901a\u5e38\u306e2\u500d\u4ee5\u4e0a\u306e\u7b4b\u8089\u91cf\u3092\u6301\u3064\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u304a\u308a\u3001\u30d2\u30c8\u306b\u304a\u3044\u3066\u3082\u3053\u306e\u907a\u4f1d\u5b50\u304c\u7b4b\u529b\u306e\u767a\u9054\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>ACTN2\u907a\u4f1d\u5b50\u3068\u901f\u7b4b\u306e\u767a\u9054<\/strong><\/h4>\n\n\n\n<p><strong>ACTN2\u907a\u4f1d\u5b50<\/strong>\u306f\u3001ACTN3\u3068\u540c\u69d8\u306b\u7b4b\u7dda\u7dad\u306e\u69cb\u9020\u3092\u7dad\u6301\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u7279\u306b\u901f\u7b4b\u306e\u6a5f\u80fd\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002ACTN3\u3068\u7570\u306a\u308a\u3001ACTN2\u306f\u3059\u3079\u3066\u306e\u7b4b\u7dda\u7dad\u30bf\u30a4\u30d7\u3067\u767a\u73fe\u3059\u308b\u305f\u3081\u3001\u6301\u4e45\u529b\u3068\u7b4b\u529b\u306e\u30d0\u30e9\u30f3\u30b9\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08journals.lww.com\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u591a\u578b\u3092\u6301\u3064\u4eba\u306f\u3001\u7206\u767a\u7684\u306a\u30d1\u30ef\u30fc\u3092\u5fc5\u8981\u3068\u3059\u308b\u30b9\u30dd\u30fc\u30c4\uff08\u4f8b\uff1a\u30a6\u30a8\u30a4\u30c8\u30ea\u30d5\u30c6\u30a3\u30f3\u30b0\u3001\u30b9\u30d7\u30ea\u30f3\u30c8\uff09\u3067\u512a\u308c\u305f\u80fd\u529b\u3092\u767a\u63ee\u3057\u3084\u3059\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c1c75850-7fff-687c-4b21-f5ae352707b1\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u4e73\u9178\u8010\u6027\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-1024x683.jpg\" alt=\"\n\u75b2\u52b4\u30fb\u606f\u5207\u308c\u30fb\u30af\u30fc\u30eb\u30c0\u30a6\u30f3\u306e\u82e5\u3044\u7537\u6027\" class=\"wp-image-9592\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31518446_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u904b\u52d5\u4e2d\u306b\u84c4\u7a4d\u3059\u308b\u4e73\u9178\u306f\u3001\u7b4b\u8089\u75b2\u52b4\u306e\u8981\u56e0\u306e\u4e00\u3064\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e73\u9178\u306e\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u80fd\u529b\uff08\u4e73\u9178\u9664\u53bb\u901f\u5ea6\uff09\u3082\u907a\u4f1d\u7684\u306a\u5f71\u97ff\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>MCT1\u907a\u4f1d\u5b50\u3068\u4e73\u9178\u8f38\u9001<\/strong><\/h4>\n\n\n\n<p><strong>MCT1\uff08\u30e2\u30ce\u30ab\u30eb\u30dc\u30f3\u9178\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc1\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u4e73\u9178\u3092\u7b4b\u8089\u7d30\u80de\u304b\u3089\u8840\u6d41\u3078\u8f38\u9001\u3059\u308b\u5f79\u5272\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002MCT1\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u4e73\u9178\u306e\u9664\u53bb\u80fd\u529b\u304c\u9ad8\u304f\u3001\u9577\u6642\u9593\u306e\u904b\u52d5\u3067\u3082\u7b4b\u8089\u306e\u9178\u6027\u5316\u3092\u6291\u3048\u3084\u3059\u3044\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08sportsmedopen.com\uff09\u3002<\/p>\n\n\n\n<p>\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u306b\u3068\u3063\u3066\u3001MCT1\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u306f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306e\u5411\u4e0a\u306b\u76f4\u7d50\u3059\u308b\u305f\u3081\u3001\u3053\u306e\u907a\u4f1d\u60c5\u5831\u3092\u6d3b\u7528\u3057\u3066\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u8a08\u753b\u3092\u7acb\u3066\u308b\u3053\u3068\u304c\u6709\u76ca\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>PGC-1\u03b1\u907a\u4f1d\u5b50\u3068\u6709\u9178\u7d20\u80fd\u529b<\/strong><\/h4>\n\n\n\n<p><strong>PGC-1\u03b1\uff08\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u5897\u6b96\u56e0\u5b50\u6d3b\u6027\u5316\u53d7\u5bb9\u4f53\u30ac\u30f3\u30de\u88dc\u52a9\u6d3b\u6027\u5316\u56e0\u5b501-\u30a2\u30eb\u30d5\u30a1\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u6709\u9178\u7d20\u904b\u52d5\u306b\u5bfe\u3059\u308b\u9069\u5fdc\u3092\u8abf\u7bc0\u3059\u308b\u907a\u4f1d\u5b50\u3067\u3042\u308a\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u5897\u52a0\u3084\u4e73\u9178\u9664\u53bb\u80fd\u529b\u306e\u5411\u4e0a\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u3002PGC-1\u03b1\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u6301\u4e45\u7cfb\u7af6\u6280\u306b\u304a\u3044\u3066\u9ad8\u3044\u80fd\u529b\u3092\u767a\u63ee\u3059\u308b\u50be\u5411\u304c\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1569904819304776\">sciencedirect.com<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001PGC-1\u03b1\u306e\u767a\u73fe\u306f\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u6804\u990a\u6226\u7565\uff08\u4f8b\uff1a\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3092\u591a\u304f\u542b\u3080\u98df\u54c1\u306e\u6442\u53d6\uff09\u306b\u3088\u3063\u3066\u8abf\u7bc0\u3067\u304d\u308b\u305f\u3081\u3001\u907a\u4f1d\u7684\u7279\u6027\u306b\u5fdc\u3058\u305f\u6301\u4e45\u529b\u5411\u4e0a\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u30ea\u30ab\u30d0\u30ea\u30fc\u80fd\u529b<\/strong><\/h3>\n\n\n\n<p>\u30a2\u30b9\u30ea\u30fc\u30c8\u304c\u6301\u4e45\u529b\u3084\u7b4b\u529b\u3092\u6700\u5927\u9650\u306b\u6d3b\u304b\u3059\u305f\u3081\u306b\u306f\u3001\u9069\u5207\u306a\u30ea\u30ab\u30d0\u30ea\u30fc\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u30ea\u30ab\u30d0\u30ea\u30fc\u80fd\u529b\u306b\u3082\u907a\u4f1d\u7684\u306a\u5f71\u97ff\u304c\u3042\u308a\u3001\u500b\u3005\u306e\u907a\u4f1d\u5b50\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u57fa\u3065\u3044\u305f\u56de\u5fa9\u6226\u7565\u3092\u5c0e\u5165\u3059\u308b\u3053\u3068\u3067\u3001\u7af6\u6280\u529b\u306e\u5411\u4e0a\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>CRP\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u708e\u75c7\u30de\u30fc\u30ab\u30fc\u3067\u3042\u308bC\u53cd\u5fdc\u6027\u30bf\u30f3\u30d1\u30af\u8cea\uff08CRP\uff09\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3057\u3001\u7b4b\u640d\u50b7\u5f8c\u306e\u56de\u5fa9\u901f\u5ea6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u7279\u5b9a\u306eCRP\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e\u708e\u75c7\u304c\u9577\u5f15\u304d\u3084\u3059\u3044\u305f\u3081\u3001\u56de\u5fa9\u306e\u305f\u3081\u306e\u6804\u990a\u6226\u7565\u3084\u30b9\u30c8\u30ec\u30c3\u30c1\u306e\u5c0e\u5165\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\uff08bmj.com\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u304c\u6301\u4e45\u529b\u3084\u7b4b\u529b\u3001\u56de\u5fa9\u80fd\u529b\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u500b\u3005\u306b\u6700\u9069\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u6804\u990a\u6226\u7565\u3092\u7d44\u307f\u7acb\u3066\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u9178\u7d20\u4f9b\u7d66\u80fd\u529b<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u306b\u3068\u3063\u3066\u3001\u9178\u7d20\u4f9b\u7d66\u80fd\u529b\u306f\u7af6\u6280\u6210\u7e3e\u3092\u5927\u304d\u304f\u5de6\u53f3\u3059\u308b\u8981\u7d20\u3067\u3059\u3002\u9178\u7d20\u4f9b\u7d66\u80fd\u529b\u306f\u3001\u5fc3\u80ba\u6a5f\u80fd\u3084\u8840\u6db2\u306e\u9178\u7d20\u904b\u642c\u80fd\u529b\u3068\u5bc6\u63a5\u306b\u95a2\u4fc2\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306f\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u90e8\u5206\u7684\u306b\u5236\u5fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>EPO\u907a\u4f1d\u5b50\u3068\u8d64\u8840\u7403\u7523\u751f<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/22138195_m-1024x683.jpg\" alt=\"\n\u30a6\u30a9\u30fc\u30ad\u30f3\u30b0\u30fb\u904b\u52d5\u3059\u308b\u5973\u6027\" class=\"wp-image-9599\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22138195_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22138195_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22138195_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22138195_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/22138195_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>EPO\uff08\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u8d64\u8840\u7403\u306e\u7523\u751f\u3092\u4fc3\u9032\u3059\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\u306e\u751f\u6210\u3092\u8abf\u7bc0\u3057\u307e\u3059\u3002\u8d64\u8840\u7403\u306f\u9178\u7d20\u3092\u7b4b\u8089\u306b\u904b\u642c\u3059\u308b\u5f79\u5272\u3092\u6301\u3063\u3066\u304a\u308a\u3001EPO\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u591a\u578b\u3092\u6301\u3064\u4eba\u306f\u3001\u8d64\u8840\u7403\u6570\u304c\u591a\u304f\u3001\u9178\u7d20\u904b\u642c\u80fd\u529b\u304c\u9ad8\u3044\u305f\u3081\u3001\u6301\u4e45\u7cfb\u30b9\u30dd\u30fc\u30c4\u3067\u512a\u308c\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u767a\u63ee\u3057\u3084\u3059\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08journals.lww.com\uff09\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>HIF1A\u907a\u4f1d\u5b50\u3068\u4f4e\u9178\u7d20\u74b0\u5883\u3078\u306e\u9069\u5fdc<\/strong><\/h4>\n\n\n\n<p><strong>HIF1A\uff08\u4f4e\u9178\u7d20\u8a98\u5c0e\u56e0\u5b501\u03b1\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u4f4e\u9178\u7d20\u72b6\u614b\u306b\u9069\u5fdc\u3059\u308b\u305f\u3081\u306e\u907a\u4f1d\u5b50\u3067\u3042\u308a\u3001\u9ad8\u5730\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306e\u52b9\u679c\u3092\u9ad8\u3081\u308b\u8981\u56e0\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002HIF1A\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u9178\u7d20\u6fc3\u5ea6\u304c\u4f4e\u3044\u74b0\u5883\u3067\u3082\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\u306e\u751f\u6210\u304c\u6d3b\u767a\u306b\u306a\u308a\u3001\u6301\u4e45\u529b\u304c\u5411\u4e0a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41598-020-67810-y\">nature.com<\/a>\uff09\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>NOS3\u907a\u4f1d\u5b50\u3068\u8840\u7ba1\u62e1\u5f35<\/strong><\/h4>\n\n\n\n<p><strong>NOS3\uff08\u4e00\u9178\u5316\u7a92\u7d20\u5408\u6210\u9175\u7d203\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u4e00\u9178\u5316\u7a92\u7d20\uff08NO\uff09\u3092\u751f\u6210\u3057\u3001\u8840\u7ba1\u62e1\u5f35\u3092\u4fc3\u9032\u3059\u308b\u50cd\u304d\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u306b\u3068\u3063\u3066\u3001\u8840\u6d41\u306e\u6539\u5584\u306f\u7b4b\u8089\u3078\u306e\u9178\u7d20\u4f9b\u7d66\u3092\u5411\u4e0a\u3055\u305b\u3001\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306e\u5411\u4e0a\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002\u7279\u5b9a\u306eNOS3\u907a\u4f1d\u5b50\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u4e00\u9178\u5316\u7a92\u7d20\u306e\u751f\u6210\u80fd\u529b\u304c\u9ad8\u304f\u3001\u8840\u6d41\u306e\u5faa\u74b0\u304c\u826f\u597d\u3067\u3042\u308b\u305f\u3081\u3001\u6301\u4e45\u529b\u304c\u5411\u4e0a\u3057\u3084\u3059\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S002604951730059X\">sciencedirect.com<\/a>\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7b4b\u53ce\u7e2e\u7279\u6027\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u7b4b\u529b\u3084\u30d1\u30ef\u30fc\u306f\u3001\u7b4b\u7dda\u7dad\u306e\u53ce\u7e2e\u901f\u5ea6\u3084\u30a8\u30cd\u30eb\u30ae\u30fc\u4f9b\u7d66\u80fd\u529b\u306b\u4f9d\u5b58\u3057\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u7b4b\u8089\u306e\u53ce\u7e2e\u7279\u6027\u304c\u7570\u306a\u308a\u3001\u6301\u4e45\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u3068\u30d1\u30ef\u30fc\u7cfb\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u9055\u3044\u3092\u751f\u307f\u51fa\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>RYR1\u907a\u4f1d\u5b50\u3068\u7b4b\u53ce\u7e2e\u901f\u5ea6<\/strong><\/h4>\n\n\n\n<p><strong>RYR1\uff08\u30e9\u30a4\u30a2\u30ce\u30b8\u30f3\u53d7\u5bb9\u4f531\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u7b4b\u7d30\u80de\u5185\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u653e\u51fa\u3092\u8abf\u7bc0\u3057\u3001\u7b4b\u53ce\u7e2e\u306e\u901f\u3055\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u77ed\u8ddd\u96e2\u8d70\u3084\u91cd\u91cf\u6319\u3052\u306a\u3069\u3001\u7206\u767a\u7684\u306a\u7b4b\u53ce\u7e2e\u304c\u5fc5\u8981\u306a\u7af6\u6280\u3067\u306f\u3001RYR1\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u304c\u512a\u308c\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u767a\u63ee\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08jap.physiology.org\uff09\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>SLC16A1\u907a\u4f1d\u5b50\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4f9b\u7d66<\/strong><\/h4>\n\n\n\n<p><strong>SLC16A1\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u4e73\u9178\u8f38\u9001\u306b\u95a2\u4e0e\u3059\u308bMCT1\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u7b4b\u8089\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4f9b\u7d66\u80fd\u529b\u3092\u8abf\u7bc0\u3057\u307e\u3059\u3002\u6301\u4e45\u529b\u306e\u9ad8\u3044\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001SLC16A1\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u904b\u52d5\u4e2d\u306b\u751f\u6210\u3055\u308c\u305f\u4e73\u9178\u3092\u52b9\u7387\u3088\u304f\u9664\u53bb\u3057\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3092\u7dad\u6301\u3067\u304d\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff08cell.com\uff09\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u7b4b\u8089\u306e\u640d\u50b7\u8010\u6027<\/strong><\/h3>\n\n\n\n<p>\u7b4b\u529b\u3084\u6301\u4e45\u529b\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u6700\u5927\u9650\u306b\u767a\u63ee\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u7b4b\u8089\u306e\u640d\u50b7\u8010\u6027\u3082\u91cd\u8981\u3067\u3059\u3002\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306f\u3001\u7b4b\u640d\u50b7\u306e\u30ea\u30b9\u30af\u3084\u56de\u5fa9\u901f\u5ea6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>COL1A1\u907a\u4f1d\u5b50\u3068\u8171\u30fb\u976d\u5e2f\u306e\u5f37\u5ea6<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/2170021_m-1024x683.jpg\" alt=\"\n\u8a66\u5408\u3092\u3059\u308b\u30d0\u30ec\u30fc\u30dc\u30fc\u30eb\u9078\u624b\" class=\"wp-image-9606\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/2170021_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/2170021_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/2170021_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/2170021_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/2170021_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>COL1A1\uff08\u30b3\u30e9\u30fc\u30b2\u30f3I\u578b\u03b11\u9396\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u8171\u3084\u976d\u5e2f\u306e\u5f37\u5ea6\u3092\u6c7a\u5b9a\u3059\u308b\u907a\u4f1d\u5b50\u3067\u3059\u3002\u7279\u5b9a\u306eCOL1A1\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u976d\u5e2f\u3084\u8171\u304c\u4e08\u592b\u3067\u3042\u308a\u3001\u30b9\u30dd\u30fc\u30c4\u4e2d\u306e\u602a\u6211\u3092\u3057\u306b\u304f\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u9006\u306b\u3001\u5225\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u976d\u5e2f\u640d\u50b7\u3084\u30a2\u30ad\u30ec\u30b9\u8171\u65ad\u88c2\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u4e88\u9632\u7684\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u30b1\u30a2\u304c\u5fc5\u8981\u306b\u306a\u308a\u307e\u3059\uff08bmj.com\uff09\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>GDF5\u907a\u4f1d\u5b50\u3068\u95a2\u7bc0\u306e\u5065\u5eb7<\/strong><\/h4>\n\n\n\n<p><strong>GDF5\uff08\u6210\u9577\u5206\u5316\u56e0\u5b505\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u95a2\u7bc0\u306e\u5065\u5eb7\u3084\u8edf\u9aa8\u306e\u4fee\u5fa9\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u95a2\u7bc0\u708e\u3084\u8edf\u9aa8\u640d\u50b7\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u7279\u306b\u9577\u6642\u9593\u306e\u30e9\u30f3\u30cb\u30f3\u30b0\u3084\u30b8\u30e3\u30f3\u30d7\u3092\u4f34\u3046\u30b9\u30dd\u30fc\u30c4\u306e\u30a2\u30b9\u30ea\u30fc\u30c8\u306b\u3068\u3063\u3066\u306f\u91cd\u8981\u306a\u8981\u7d20\u3068\u306a\u308a\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41598-018-21487-1\">nature.com<\/a>\uff09\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u795e\u7d4c\u7b4b\u5236\u5fa1<\/strong><\/h3>\n\n\n\n<p>\u7b4b\u529b\u3084\u6301\u4e45\u529b\u3092\u6700\u5927\u9650\u306b\u767a\u63ee\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u795e\u7d4c\u7b4b\u306e\u9069\u5fdc\u80fd\u529b\u3082\u91cd\u8981\u3067\u3059\u3002\u907a\u4f1d\u7684\u306a\u8981\u56e0\u304c\u3001\u904b\u52d5\u5b66\u7fd2\u3084\u795e\u7d4c\u4f1d\u9054\u306e\u52b9\u7387\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>SNAP25\u907a\u4f1d\u5b50\u3068\u795e\u7d4c\u4f1d\u9054\u901f\u5ea6<\/strong><\/h4>\n\n\n\n<p><strong>SNAP25\uff08\u30b7\u30ca\u30d7\u30b9\u95a2\u9023\u30bf\u30f3\u30d1\u30af\u8cea25\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u653e\u51fa\u3092\u5236\u5fa1\u3057\u3001\u7b4b\u8089\u306e\u52d5\u54e1\u52b9\u7387\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u7279\u5b9a\u306eSNAP25\u907a\u4f1d\u5b50\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u795e\u7d4c\u4f1d\u9054\u901f\u5ea6\u304c\u901f\u304f\u3001\u52d5\u4f5c\u306e\u6b63\u78ba\u6027\u3084\u53cd\u5fdc\u6642\u9593\u304c\u5411\u4e0a\u3059\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\uff08<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0896627317303962\">sciencedirect.com<\/a>\uff09\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>DRD4\u907a\u4f1d\u5b50\u3068\u904b\u52d5\u306e\u52d5\u6a5f\u3065\u3051<\/strong><\/h4>\n\n\n\n<p><strong>DRD4\uff08\u30c9\u30fc\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53D4\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u904b\u52d5\u3078\u306e\u52d5\u6a5f\u3065\u3051\u3084\u96c6\u4e2d\u529b\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u6301\u7d9a\u7684\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306b\u5bfe\u3059\u308b\u610f\u6b32\u304c\u9ad8\u304f\u3001\u9577\u671f\u9593\u306b\u308f\u305f\u308b\u904b\u52d5\u30d7\u30ed\u30b0\u30e9\u30e0\u3092\u7d99\u7d9a\u3057\u3084\u3059\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41598-019-44632-3\">nature.com<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u304c\u4f53\u529b\u7279\u6027\u3084\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u306f\u591a\u5c90\u306b\u308f\u305f\u308a\u3001\u500b\u3005\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u7387\u7684\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u56de\u5fa9\u6226\u7565\u3092\u8a2d\u8a08\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u6804\u990a\u6442\u53d6\u306e\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u6301\u4e45\u529b\u3084\u7b4b\u529b\u306e\u767a\u9054\u306b\u306f\u3001\u9069\u5207\u306a\u6804\u990a\u6442\u53d6\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u500b\u3005\u306e\u6804\u990a\u7d20\u306e\u5438\u53ce\u3084\u4ee3\u8b1d\u306b\u306f\u907a\u4f1d\u7684\u8981\u56e0\u304c\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u6804\u990a\u306e\u5229\u7528\u52b9\u7387\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u907a\u4f1d\u7684\u7279\u6027\u306b\u5fdc\u3058\u305f\u98df\u4e8b\u6226\u7565\u3092\u7acb\u3066\u308b\u3053\u3068\u3067\u3001\u30b9\u30dd\u30fc\u30c4\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u5411\u4e0a\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>FTO\u907a\u4f1d\u5b50\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31265917_m-1024x585.jpg\" alt=\"\n\u8a66\u5408\u3092\u3059\u308b\u30d0\u30ec\u30fc\u30dc\u30fc\u30eb\u9078\u624b\" class=\"wp-image-9613\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31265917_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31265917_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31265917_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31265917_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31265917_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>FTO\uff08\u8102\u80aa\u8cea\u91cf\u30fb\u80a5\u6e80\u95a2\u9023\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3084\u98df\u6b32\u8abf\u7bc0\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u4f53\u8102\u80aa\u306e\u84c4\u7a4d\u3068\u5bc6\u63a5\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002FTO\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u591a\u578b\u3092\u6301\u3064\u4eba\u306f\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u6d88\u8cbb\u91cf\u304c\u4f4e\u304f\u3001\u8102\u80aa\u3092\u84c4\u7a4d\u3057\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308b\u305f\u3081\u3001\u6301\u4e45\u529b\u304c\u6c42\u3081\u3089\u308c\u308b\u7af6\u6280\u306b\u304a\u3044\u3066\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/journals.plos.org\/plosgenetics\/article?id=10.1371\/journal.pgen.1006362\">journals.plos.org<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u3092\u6301\u3064\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u9ad8\u8102\u80aa\u98df\u3092\u907f\u3051\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u70ad\u6c34\u5316\u7269\u306e\u9069\u5207\u306a\u30d0\u30e9\u30f3\u30b9\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u6709\u9178\u7d20\u904b\u52d5\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u4f53\u8102\u80aa\u306e\u5897\u52a0\u3092\u6291\u3048\u3064\u3064\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u3092\u6700\u9069\u5316\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>PPARGC1A\u907a\u4f1d\u5b50\u3068\u8102\u8cea\u4ee3\u8b1d<\/strong><\/h4>\n\n\n\n<p><strong>PPARGC1A\uff08\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u5897\u6b96\u56e0\u5b50\u6d3b\u6027\u5316\u53d7\u5bb9\u4f53\u30ac\u30f3\u30de\u88dc\u52a9\u6d3b\u6027\u5316\u56e0\u5b501-\u30a2\u30eb\u30d5\u30a1\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u8102\u8cea\u4ee3\u8b1d\u3084\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u6a5f\u80fd\u3092\u8abf\u7bc0\u3059\u308b\u91cd\u8981\u306a\u907a\u4f1d\u5b50\u3067\u3059\u3002\u6301\u4e45\u529b\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u591a\u304f\u306f\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3063\u3066\u304a\u308a\u3001\u8102\u80aa\u3092\u30a8\u30cd\u30eb\u30ae\u30fc\u6e90\u3068\u3057\u3066\u52b9\u7387\u7684\u306b\u5229\u7528\u3059\u308b\u80fd\u529b\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41598-019-54859-9\">nature.com<\/a>\uff09\u3002<\/p>\n\n\n\n<p>PPARGC1A\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u9ad8\u3081\u308b\u305f\u3081\u306b\u306f\u3001\u6301\u7d9a\u7684\u306a\u6709\u9178\u7d20\u904b\u52d5\u304c\u52b9\u679c\u7684\u3067\u3042\u308a\u3001\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\uff08\u9b5a\u6cb9\uff09\u3084\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\uff08\u7dd1\u8336\u3001\u30d6\u30eb\u30fc\u30d9\u30ea\u30fc\uff09\u3092\u591a\u304f\u542b\u3080\u98df\u54c1\u306e\u6442\u53d6\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u6301\u4e45\u529b\u306e\u5411\u4e0a\u3068\u30a8\u30cd\u30eb\u30ae\u30fc\u52b9\u7387\u306e\u6700\u9069\u5316\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>AMY1\u907a\u4f1d\u5b50\u3068\u70ad\u6c34\u5316\u7269\u4ee3\u8b1d<\/strong><\/h4>\n\n\n\n<p><strong>AMY1\uff08\u30a2\u30df\u30e9\u30fc\u30bc1\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u553e\u6db2\u4e2d\u306e\u30a2\u30df\u30e9\u30fc\u30bc\u9175\u7d20\u306e\u91cf\u3092\u6c7a\u5b9a\u3057\u3001\u70ad\u6c34\u5316\u7269\u306e\u6d88\u5316\u3068\u5438\u53ce\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002AMY1\u907a\u4f1d\u5b50\u306e\u30b3\u30d4\u30fc\u6570\u304c\u591a\u3044\u4eba\u306f\u3001\u30c7\u30f3\u30d7\u30f3\u3092\u7d20\u65e9\u304f\u5206\u89e3\u3057\u3001\u30b0\u30eb\u30b3\u30fc\u30b9\u3068\u3057\u3066\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u4f9b\u7d66\u3059\u308b\u80fd\u529b\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1550413115002413\">sciencedirect.com<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u6301\u4e45\u529b\u7cfb\u306e\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u3092\u7d20\u65e9\u304f\u4f9b\u7d66\u3067\u304d\u308bAMY1\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u3053\u3068\u3067\u3001\u7af6\u6280\u4e2d\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u7dad\u6301\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u4e00\u65b9\u3001AMY1\u306e\u30b3\u30d4\u30fc\u6570\u304c\u5c11\u306a\u3044\u4eba\u306f\u3001\u70ad\u6c34\u5316\u7269\u306e\u6d88\u5316\u5438\u53ce\u304c\u9045\u304f\u3001\u8840\u7cd6\u5024\u306e\u5909\u52d5\u304c\u5927\u304d\u3044\u305f\u3081\u3001\u8a66\u5408\u524d\u306e\u98df\u4e8b\u8a08\u753b\u3092\u614e\u91cd\u306b\u884c\u3046\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u7b4b\u8089\u306e\u640d\u50b7\u3068\u56de\u5fa9\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u7b4b\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u6301\u4e45\u904b\u52d5\u306f\u7b4b\u640d\u50b7\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u304c\u3001\u56de\u5fa9\u901f\u5ea6\u306f\u500b\u3005\u306e\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u304c\u7b4b\u7e4a\u7dad\u306e\u4fee\u5fa9\u3084\u708e\u75c7\u5fdc\u7b54\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u56de\u5fa9\u306e\u52b9\u7387\u3092\u5de6\u53f3\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>CKM\u907a\u4f1d\u5b50\u3068\u7b4b\u640d\u50b7\u306e\u30ea\u30b9\u30af<\/strong><\/h4>\n\n\n\n<p><strong>CKM\uff08\u30af\u30ec\u30a2\u30c1\u30f3\u30ad\u30ca\u30fc\u30bcM\u578b\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u7b4b\u8089\u5185\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u904b\u52d5\u5f8c\u306e\u7b4b\u640d\u50b7\u306e\u7a0b\u5ea6\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u7279\u5b9a\u306eCKM\u907a\u4f1d\u5b50\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u7b4b\u8089\u306e\u30c0\u30e1\u30fc\u30b8\u304c\u5927\u304d\u304f\u306a\u308a\u3084\u3059\u304f\u3001\u56de\u5fa9\u304c\u9045\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\uff08<a href=\"https:\/\/bjsm.bmj.com\/content\/54\/9\/538\">bmj.com<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001CKM\u907a\u4f1d\u5b50\u306e\u30ea\u30b9\u30af\u3092\u6301\u3064\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e\u9069\u5207\u306a\u56de\u5fa9\u6226\u7565\uff08\u30af\u30ec\u30a2\u30c1\u30f3\u88dc\u7d66\u3001\u30a2\u30a4\u30b9\u30d0\u30b9\u3001\u30b9\u30c8\u30ec\u30c3\u30c1\uff09\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>IL6\u907a\u4f1d\u5b50\u3068\u708e\u75c7\u53cd\u5fdc<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/3291088_m-1024x683.jpg\" alt=\"\n\u30eb\u30fc\u30e0\u30a6\u30a7\u30a2\u306e\u5973\u6027\" class=\"wp-image-9620\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3291088_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3291088_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3291088_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3291088_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3291088_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>IL6\uff08\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f36\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u708e\u75c7\u5fdc\u7b54\u3092\u8abf\u7bc0\u3059\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u751f\u6210\u3092\u5236\u5fa1\u3057\u3001\u904b\u52d5\u5f8c\u306e\u7b4b\u56de\u5fa9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002IL6\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u708e\u75c7\u304c\u9577\u5f15\u304d\u3084\u3059\u304f\u3001\u7b4b\u8089\u306e\u56de\u5fa9\u304c\u9045\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41598-020-63327-5\">nature.com<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u60c5\u5831\u3092\u57fa\u306b\u3001IL6\u306e\u767a\u73fe\u304c\u9ad8\u3044\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u3001\u6297\u708e\u75c7\u4f5c\u7528\u306e\u3042\u308b\u98df\u54c1\uff08\u30bf\u30fc\u30e1\u30ea\u30c3\u30af\u3001\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\uff09\u3092\u6442\u53d6\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u3084\u7761\u7720\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u91cd\u8981\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c1c75850-7fff-687c-4b21-f5ae352707b1\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3068\u907a\u4f1d\u5b50\u306e\u76f8\u4e92\u4f5c\u7528<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u7684\u8981\u56e0\u304c\u6301\u4e45\u529b\u3084\u7b4b\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u306f\u78ba\u304b\u3067\u3059\u304c\u3001\u74b0\u5883\u8981\u56e0\uff08\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3001\u6804\u990a\u3001\u751f\u6d3b\u7fd2\u6163\uff09\u3082\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u6700\u65b0\u306e\u7814\u7a76\u3067\u306f\u3001\u907a\u4f1d\u5b50\u3068\u74b0\u5883\u306e\u76f8\u4e92\u4f5c\u7528\u304c\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u6c7a\u5b9a\u3059\u308b\u91cd\u8981\u306a\u8981\u7d20\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u767a\u73fe\u3068\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9<\/strong><\/h4>\n\n\n\n<p>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3068\u306f\u3001DNA\u306e\u5869\u57fa\u914d\u5217\u3092\u5909\u3048\u305a\u306b\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u5236\u5fa1\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u6307\u3057\u307e\u3059\u3002\u904b\u52d5\u3084\u98df\u4e8b\u3001\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u306b\u3088\u3063\u3066\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u4fc3\u9032\u307e\u305f\u306f\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u6301\u4e45\u529b\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u306fPPARGC1A\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u5897\u52a0\u3055\u305b\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u751f\u6210\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2211124721003281\">sciencedirect.com<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u7406\u89e3\u3057\u3001\u305d\u308c\u306b\u5fdc\u3058\u305f\u74b0\u5883\u8981\u56e0\u3092\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u6301\u4e45\u529b\u3084\u7b4b\u529b\u306e\u5411\u4e0a\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u3053\u3068\u304c\u53ef\u80fd\u3068\u306a\u308a\u307e\u3059\u3002\u79d1\u5b66\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u907a\u4f1d\u7684\u7279\u6027\u3092\u6d3b\u304b\u3057\u305f\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u5411\u4e0a\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u7761\u7720\u306e\u8cea<\/strong><\/h3>\n\n\n\n<p>\u7761\u7720\u306f\u7b4b\u529b\u3084\u6301\u4e45\u529b\u306e\u5411\u4e0a\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u5f8c\u306e\u56de\u5fa9\u306b\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u907a\u4f1d\u5b50\u306f\u7761\u7720\u306e\u8cea\u3084\u6301\u7d9a\u6642\u9593\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u30a2\u30b9\u30ea\u30fc\u30c8\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u3082\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>CLOCK\u907a\u4f1d\u5b50\u3068\u4f53\u5185\u30ea\u30ba\u30e0<\/strong><\/h4>\n\n\n\n<p><strong>CLOCK\uff08Circadian Locomotor Output Cycles Kaput\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u4f53\u5185\u6642\u8a08\u3092\u8abf\u7bc0\u3057\u3001\u7761\u7720\u30d1\u30bf\u30fc\u30f3\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u7279\u5b9a\u306eCLOCK\u907a\u4f1d\u5b50\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u65e9\u5bdd\u65e9\u8d77\u304d\u306e\u50be\u5411\u304c\u5f37\u304f\u3001\u671d\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u304c\u5411\u4e0a\u3057\u3084\u3059\u3044\u4e00\u65b9\u3067\u3001\u591c\u578b\u306e\u30ea\u30ba\u30e0\u3092\u6301\u3064\u4eba\u306f\u5915\u65b9\u4ee5\u964d\u306e\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u8a66\u5408\u3067\u9ad8\u3044\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u767a\u63ee\u3057\u3084\u3059\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/academic.oup.com\/sleep\/article\/42\/6\/zsz110\/5488647\">academic.oup.com<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30a2\u30b9\u30ea\u30fc\u30c8\u306f\u81ea\u5206\u306e\u4f53\u5185\u30ea\u30ba\u30e0\u306b\u6700\u9069\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u6642\u9593\u3092\u9078\u3076\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>ADA\u907a\u4f1d\u5b50\u3068\u6df1\u3044\u7761\u7720<\/strong><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/3128651_m-1024x683.jpg\" alt=\"\n\u30d9\u30c3\u30c9\u3067\u5bdd\u308b\u7537\u60273\" class=\"wp-image-9627\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3128651_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3128651_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3128651_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3128651_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/3128651_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>ADA\uff08\u30a2\u30c7\u30ce\u30b7\u30f3\u30c7\u30a2\u30df\u30ca\u30fc\u30bc\uff09\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u30ce\u30f3\u30ec\u30e0\u7761\u7720\uff08\u6df1\u3044\u7761\u7720\uff09\u306e\u8cea\u3092\u6c7a\u5b9a\u3059\u308b\u8981\u56e0\u306e\u4e00\u3064\u3067\u3059\u3002ADA\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u6df1\u3044\u7761\u7720\u3092\u9577\u6642\u9593\u7dad\u6301\u3057\u3084\u3059\u304f\u3001\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u304c\u6d3b\u767a\u306b\u306a\u308b\u305f\u3081\u3001\u7b4b\u8089\u306e\u56de\u5fa9\u3084\u30ea\u30ab\u30d0\u30ea\u30fc\u304c\u65e9\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\uff08<a href=\"https:\/\/journals.physiology.org\/doi\/full\/10.1152\/japplphysiol.00130.2014\">journals.physiology.org<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u6301\u3064\u4eba\u306f\u3001\u8cea\u306e\u9ad8\u3044\u7761\u7720\u3092\u78ba\u4fdd\u3059\u308b\u3053\u3068\u3067\u3001\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u52b9\u679c\u3092\u6700\u5927\u5316\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u9006\u306b\u3001\u7761\u7720\u306e\u8cea\u304c\u4f4e\u3044\u4eba\u306f\u3001\u5bdd\u308b\u524d\u306e\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3092\u907f\u3051\u305f\u308a\u3001\u7761\u7720\u74b0\u5883\u3092\u6539\u5584\u3057\u305f\u308a\u3059\u308b\u3053\u3068\u3067\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u3092\u88dc\u3046\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> 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class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> 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