{"id":9785,"date":"2025-03-12T04:48:00","date_gmt":"2025-03-12T04:48:00","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=9785"},"modified":"2025-03-12T04:48:01","modified_gmt":"2025-03-12T04:48:01","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e5%bf%83%e3%81%ae%e5%81%a5%e5%ba%b7%ef%bc%9a%e7%a7%91%e5%ad%a6%e3%81%8c%e7%a4%ba%e3%81%99%e5%b9%b8%e7%a6%8f%e3%81%ae%e3%82%ab%e3%82%ae","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e5%bf%83%e3%81%ae%e5%81%a5%e5%ba%b7%ef%bc%9a%e7%a7%91%e5%ad%a6%e3%81%8c%e7%a4%ba%e3%81%99%e5%b9%b8%e7%a6%8f%e3%81%ae%e3%82%ab%e3%82%ae\/","title":{"rendered":"\u907a\u4f1d\u5b50\u3068\u5fc3\u306e\u5065\u5eb7\uff1a\u79d1\u5b66\u304c\u793a\u3059\u5e78\u798f\u306e\u30ab\u30ae"},"content":{"rendered":"\n<p>\u4eba\u9593\u306e\u5e78\u798f\u3084\u5fc3\u306e\u5065\u5eb7\u306f\u3001\u74b0\u5883\u8981\u56e0\u3060\u3051\u3067\u306a\u304f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u3082\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u306f\u3001\u907a\u4f1d\u5b50\u304c\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3001\u6c17\u5206\u306e\u5b89\u5b9a\u3001\u793e\u4f1a\u6027\u3001\u5171\u611f\u529b\u3001\u3055\u3089\u306b\u306f\u5e78\u798f\u611f\u305d\u306e\u3082\u306e\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8133\u5185\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3084\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u3092\u8abf\u6574\u3059\u308b\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u304c\u3001\u79c1\u305f\u3061\u306e\u6c17\u5206\u3084\u7cbe\u795e\u7684\u5065\u5eb7\u3092\u6c7a\u5b9a\u3059\u308b\u91cd\u8981\u306a\u8981\u7d20\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u907a\u4f1d\u5b50\u3068\u5fc3\u306e\u5065\u5eb7\u306e\u95a2\u4fc2\u3001\u5e78\u798f\u3092\u5de6\u53f3\u3059\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50\u3001\u79d1\u5b66\u7684\u306b\u691c\u8a3c\u3055\u308c\u305f\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u6cd5\u3001\u907a\u4f1d\u5b50\u306b\u57fa\u3065\u3044\u305f\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2\u306e\u6700\u524d\u7dda\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>1. \u5e78\u798f\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1.1 \u5e78\u798f\u611f\u306e\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h3>\n\n\n\n<p>\u5e78\u798f\u611f\u306f\u3001\u74b0\u5883\u8981\u56e0\u3068\u907a\u4f1d\u8981\u56e0\u304c\u8907\u96d1\u306b\u7d61\u307f\u5408\u3063\u3066\u6c7a\u5b9a\u3055\u308c\u307e\u3059\u3002\u907a\u4f1d\u7684\u5f71\u97ff\u304c\u5e78\u798f\u611f\u306b\u3069\u306e\u7a0b\u5ea6\u5bc4\u4e0e\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u306e\u7814\u7a76\u306b\u3088\u308b\u3068\u3001<strong>\u7d0430\u301c50%\u304c\u907a\u4f1d\u7684\u8981\u56e0<\/strong> \u306b\u3088\u308b\u3082\u306e\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41380-018-0039-1\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<p><strong>\u5e78\u798f\u306b\u95a2\u4e0e\u3059\u308b\u4e3b\u306a\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3068\u305d\u306e\u907a\u4f1d\u5b50<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30bb\u30ed\u30c8\u30cb\u30f3\uff085-HT\uff09<\/strong>\uff1a\u6c17\u5206\u306e\u5b89\u5b9a\u306b\u95a2\u4e0e\uff08<strong>5-HTTLPR\u907a\u4f1d\u5b50<\/strong>\uff09<\/li>\n\n\n\n<li><strong>\u30c9\u30fc\u30d1\u30df\u30f3\uff08DA\uff09<\/strong>\uff1a\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u3084\u5feb\u697d\u3092\u8abf\u6574\uff08<strong>DRD4\u907a\u4f1d\u5b50<\/strong>\uff09<\/li>\n\n\n\n<li><strong>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\uff08OT\uff09<\/strong>\uff1a\u5171\u611f\u3084\u793e\u4f1a\u7684\u7d50\u3073\u3064\u304d\u3092\u5f37\u5316\uff08<strong>OXTR\u907a\u4f1d\u5b50<\/strong>\uff09<\/li>\n\n\n\n<li><strong>\u30a8\u30f3\u30c9\u30eb\u30d5\u30a3\u30f3<\/strong>\uff1a\u30b9\u30c8\u30ec\u30b9\u7de9\u548c\u3068\u5e78\u798f\u611f\u306e\u5897\u5f37<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1.2 \u907a\u4f1d\u5b50\u304c\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306b\u4e0e\u3048\u308b\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u8010\u6027\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u305d\u306e\u4e00\u90e8\u306f\u907a\u4f1d\u306b\u3088\u3063\u3066\u6c7a\u307e\u308a\u307e\u3059\u3002\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b <strong>\u30b3\u30eb\u30c1\u30be\u30fc\u30eb<\/strong> \u306e\u5206\u6ccc\u3092\u8abf\u6574\u3059\u308b <strong>NR3C1\uff08\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\uff09<\/strong> \u3084\u3001\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u306b\u95a2\u4e0e\u3059\u308b <strong>COMT\uff08\u30ab\u30c6\u30b3\u30fc\u30eb-O-\u30e1\u30c1\u30eb\u8ee2\u79fb\u9175\u7d20\uff09<\/strong> \u306a\u3069\u306e\u907a\u4f1d\u5b50\u304c\u3001\u3053\u306e\u9055\u3044\u3092\u751f\u307f\u51fa\u3057\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41562-018-0397-1\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u904e\u654f\u306a\u53cd\u5fdc\u3092\u793a\u3059\u3053\u3068\u304c\u3042\u308a\u3001\u7cbe\u795e\u7684\u306a\u4e0d\u8abf\u306b\u9665\u308a\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3057\u3066\u9069\u5fdc\u3057\u3084\u3059\u3044\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u4eba\u306f\u3001\u30ec\u30b8\u30ea\u30a8\u30f3\u30b9\uff08\u7cbe\u795e\u7684\u56de\u5fa9\u529b\uff09\u304c\u9ad8\u304f\u3001\u56f0\u96e3\u306a\u72b6\u6cc1\u3067\u3082\u524d\u5411\u304d\u306b\u5bfe\u51e6\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>2. \u5e78\u798f\u3092\u5de6\u53f3\u3059\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2.1 5-HTTLPR\u907a\u4f1d\u5b50\uff08\u30bb\u30ed\u30c8\u30cb\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u907a\u4f1d\u5b50\uff09<\/strong><\/h3>\n\n\n\n<p>\u30bb\u30ed\u30c8\u30cb\u30f3\u306f\u3001\u300c\u5e78\u305b\u30db\u30eb\u30e2\u30f3\u300d\u3068\u3082\u547c\u3070\u308c\u3001\u6c17\u5206\u306e\u5b89\u5b9a\u3084\u4e0d\u5b89\u306e\u8efd\u6e1b\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002<strong>5-HTTLPR\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u518d\u53d6\u308a\u8fbc\u307f\u3092\u8abf\u7bc0\u3057\u3001\u305d\u306e\u6a5f\u80fd\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\uff08<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4049704\/\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>S\u578b\uff08\u77ed\u3044\u30d0\u30ea\u30a2\u30f3\u30c8\uff09<\/strong> \u3092\u6301\u3064\u4eba\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u304c\u9ad8\u304f\u3001\u4e0d\u5b89\u3084\u3046\u3064\u306e\u30ea\u30b9\u30af\u304c\u4e0a\u6607\u3059\u308b\u50be\u5411\u3002<\/li>\n\n\n\n<li><strong>L\u578b\uff08\u9577\u3044\u30d0\u30ea\u30a2\u30f3\u30c8\uff09<\/strong> \u3092\u6301\u3064\u4eba\u306f\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u518d\u53d6\u308a\u8fbc\u307f\u304c\u5b89\u5b9a\u3057\u3001\u6c17\u5206\u306e\u5b89\u5b9a\u6027\u304c\u9ad8\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2.2 DRD4\u907a\u4f1d\u5b50\uff08\u30c9\u30fc\u30d1\u30df\u30f3D4\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\uff09<\/strong><\/h3>\n\n\n\n<p>\u30c9\u30fc\u30d1\u30df\u30f3\u306f\u3001\u5831\u916c\u7cfb\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3067\u3042\u308a\u3001\u5feb\u697d\u3084\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002<strong>DRD4\u907a\u4f1d\u5b50<\/strong> \u306f\u30c9\u30fc\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53\u306e\u50cd\u304d\u3092\u8abf\u6574\u3057\u3001\u5e78\u798f\u611f\u3084\u5192\u967a\u5fc3\u3001\u597d\u5947\u5fc3\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41380-020-0707-7\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>7R\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u523a\u6fc0\u3092\u6c42\u3081\u3084\u3059\u304f\u3001\u65b0\u3057\u3044\u7d4c\u9a13\u3092\u8ffd\u3044\u6c42\u3081\u308b\u50be\u5411\u3002<\/li>\n\n\n\n<li><strong>4R\u4ee5\u4e0b\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u614e\u91cd\u3067\u5b89\u5b9a\u3057\u305f\u884c\u52d5\u3092\u3068\u308b\u50be\u5411\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2.3 OXTR\u907a\u4f1d\u5b50\uff08\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\uff09<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/4212113_m-1024x683.jpg\" alt=\"\n\u5b50\u4f9b\u3092\u62b1\u3063\u3053\u3059\u308b\u304a\u6bcd\u3055\u3093\" class=\"wp-image-9793\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4212113_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4212113_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4212113_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4212113_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/4212113_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u306f\u300c\u611b\u60c5\u30db\u30eb\u30e2\u30f3\u300d\u3068\u3082\u547c\u3070\u308c\u3001\u793e\u4f1a\u7684\u7d46\u3084\u5171\u611f\u80fd\u529b\u3092\u5f37\u5316\u3057\u307e\u3059\u3002<strong>OXTR\u907a\u4f1d\u5b50<\/strong> \u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306b\u3088\u3063\u3066\u3001\u5171\u611f\u529b\u3084\u5bfe\u4eba\u95a2\u4fc2\u306e\u8cea\u304c\u7570\u306a\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/mp201197\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>GG\u578b\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u4ed6\u8005\u3068\u306e\u95a2\u4fc2\u6027\u3092\u7bc9\u304f\u306e\u304c\u5f97\u610f\u3067\u3001\u5171\u611f\u529b\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>AA\u578b\u3084AG\u578b\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u793e\u4ea4\u6027\u304c\u4f4e\u304f\u3001\u5bfe\u4eba\u4e0d\u5b89\u3092\u62b1\u3048\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>3. \u907a\u4f1d\u5b50\u3068\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306e\u6700\u524d\u7dda<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3.1 \u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b\u500b\u5225\u5316\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u81ea\u5206\u306e\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3084\u5e78\u798f\u611f\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u578b\u3092\u7279\u5b9a\u3057\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u907a\u4f1d\u5b50\u5225\u30b9\u30c8\u30ec\u30b9\u5bfe\u7b56\u306e\u4f8b<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>5-HTTLPR S\u578b\u306e\u4eba<\/strong> \u2192 \u7791\u60f3\u3084\u904b\u52d5\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u3092\u5897\u3084\u3059\u98df\u54c1\uff08\u30d0\u30ca\u30ca\u3001\u30ca\u30c3\u30c4\uff09\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3002<\/li>\n\n\n\n<li><strong>DRD4 7R\u578b\u306e\u4eba<\/strong> \u2192 \u65b0\u3057\u3044\u4f53\u9a13\u3092\u53d6\u308a\u5165\u308c\u3001\u597d\u5947\u5fc3\u3092\u523a\u6fc0\u3059\u308b\u6d3b\u52d5\u3092\u5897\u3084\u3059\u3002<\/li>\n\n\n\n<li><strong>OXTR GG\u578b\u306e\u4eba<\/strong> \u2192 \u4eba\u3068\u306e\u4ea4\u6d41\u3092\u6d3b\u304b\u3057\u3001\u793e\u4f1a\u7684\u30b5\u30dd\u30fc\u30c8\u3092\u6d3b\u7528\u3002<\/li>\n<\/ul>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3.2 \u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\uff08\u5f8c\u5929\u7684\u907a\u4f1d\u5b50\u767a\u73fe\u5236\u5fa1\uff09<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u7684\u8981\u56e0\u306f\u6c7a\u5b9a\u7684\u3067\u306f\u306a\u304f\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306b\u3088\u3063\u3066\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u304c\u5909\u5316\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3092 <strong>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9<\/strong> \u3068\u3044\u3044\u3001\u5e78\u798f\u611f\u3092\u5411\u4e0a\u3055\u305b\u308b\u305f\u3081\u306e\u6226\u7565\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41593-020-00737-3\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u3092\u6d3b\u7528\u3057\u305f\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u904b\u52d5<\/strong>\uff08\u6709\u9178\u7d20\u904b\u52d5\u304cBDNF\u306e\u767a\u73fe\u3092\u5897\u52a0\u3055\u305b\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3092\u5411\u4e0a\uff09<\/li>\n\n\n\n<li><strong>\u98df\u4e8b<\/strong>\uff08\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3084\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u304c\u6297\u708e\u75c7\u4f5c\u7528\u3092\u6301\u3061\u3001\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u3092\u30b5\u30dd\u30fc\u30c8\uff09<\/li>\n\n\n\n<li><strong>\u7791\u60f3\u30fb\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9<\/strong>\uff08\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u5206\u6ccc\u3092\u6291\u3048\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u3092\u8abf\u6574\uff09<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u3068\u5fc3\u306e\u5065\u5eb7\u306e\u95a2\u4fc2\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u81ea\u5206\u306b\u5408\u3063\u305f\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2\u3092\u5b9f\u8df5\u3057\u3001\u3088\u308a\u9ad8\u3044\u5e78\u798f\u611f\u3092\u5f97\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u907a\u4f1d\u5b50\u89e3\u6790\u306e\u9032\u6b69\u304c\u3001\u500b\u5225\u5316\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2\u306e\u672a\u6765\u3092\u5207\u308a\u62d3\u304f\u9375\u3068\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>4. \u907a\u4f1d\u5b50\u3068\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\uff1a\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3092\u6c7a\u3081\u308b\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4.1 NR3C1\u907a\u4f1d\u5b50\u3068\u30b9\u30c8\u30ec\u30b9\u8010\u6027<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/11\/31437212_m-1024x683.jpg\" alt=\"\u30a8\u30af\u30b5\u30b5\u30a4\u30ba\u3092\u3059\u308b\u5973\u6027\" class=\"wp-image-8969\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31437212_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31437212_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31437212_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31437212_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/11\/31437212_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b<strong>\u30b3\u30eb\u30c1\u30be\u30fc\u30eb<\/strong>\u306e\u8abf\u7bc0\u306b\u306f\u3001<strong>NR3C1\uff08\u30b0\u30eb\u30b3\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\uff09\u907a\u4f1d\u5b50<\/strong>\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u30b9\u30c8\u30ec\u30b9\u6642\u306e\u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u53cd\u5fdc\u304c\u904e\u654f\u306b\u306a\u308a\u3001\u4e0d\u5b89\u3084\u3046\u3064\u75c5\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/mp2010141\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>NR3C1\u306e\u904e\u5270\u767a\u73fe<\/strong> \u2192 \u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u306e\u5206\u6ccc\u304c\u5236\u5fa1\u3057\u306b\u304f\u304f\u3001\u30b9\u30c8\u30ec\u30b9\u3078\u306e\u904e\u654f\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3059\u3002<\/li>\n\n\n\n<li><strong>NR3C1\u306e\u4f4e\u767a\u73fe<\/strong> \u2192 \u30b9\u30c8\u30ec\u30b9\u306b\u920d\u611f\u306b\u306a\u308a\u3084\u3059\u3044\u304c\u3001\u9069\u5207\u306a\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u304c\u96e3\u3057\u3044\u3053\u3068\u3082\u3042\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3092\u5411\u4e0a\u3055\u305b\u308b\u305f\u3081\u306b\u3001<strong>\u30e8\u30ac\u3084\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u3001\u9069\u5ea6\u306a\u904b\u52d5<\/strong>\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4.2 BDNF\u907a\u4f1d\u5b50\u3068\u795e\u7d4c\u53ef\u5851\u6027<\/strong><\/h3>\n\n\n\n<p><strong>BDNF\uff08\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff09<\/strong> \u306f\u3001\u8133\u306e\u795e\u7d4c\u7d30\u80de\u306e\u6210\u9577\u3084\u518d\u751f\u3092\u4fc3\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3084\u5b66\u7fd2\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u7279\u306b\u3001<strong>Val66Met\u30d0\u30ea\u30a2\u30f3\u30c8<\/strong> \u3092\u6301\u3064\u4eba\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u5bfe\u3059\u308b\u8133\u306e\u9069\u5fdc\u80fd\u529b\u304c\u4f4e\u4e0b\u3059\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/npp2010150\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Val\/Val\u578b<\/strong> \u2192 BDNF\u306e\u5206\u6ccc\u304c\u6d3b\u767a\u3067\u3001\u30b9\u30c8\u30ec\u30b9\u9069\u5fdc\u80fd\u529b\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>Met\/Met\u578b<\/strong> \u2192 BDNF\u306e\u5206\u6ccc\u304c\u4f4e\u4e0b\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>BDNF\u306e\u767a\u73fe\u3092\u4fc3\u9032\u3059\u308b\u305f\u3081\u306b\u306f\u3001<strong>\u6709\u9178\u7d20\u904b\u52d5\uff08\u30e9\u30f3\u30cb\u30f3\u30b0\u3001\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\uff09\u3001\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3092\u542b\u3080\u98df\u54c1\uff08\u30d6\u30eb\u30fc\u30d9\u30ea\u30fc\u3001\u7dd1\u8336\uff09<\/strong> \u306a\u3069\u304c\u6709\u52b9\u3067\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>4.3 COMT\u907a\u4f1d\u5b50\u3068\u30b9\u30c8\u30ec\u30b9\u51e6\u7406\u80fd\u529b<\/strong><\/h3>\n\n\n\n<p><strong>COMT\uff08\u30ab\u30c6\u30b3\u30fc\u30eb-O-\u30e1\u30c1\u30eb\u8ee2\u79fb\u9175\u7d20\uff09\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u3084\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u3068\u3044\u3063\u305f\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u4ee3\u8b1d\u306b\u95a2\u4e0e\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3084\u610f\u601d\u6c7a\u5b9a\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\uff08<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4118858\/\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Val\/Val\u578b<\/strong> \u2192 \u30c9\u30fc\u30d1\u30df\u30f3\u306e\u5206\u89e3\u304c\u901f\u304f\u3001\u30b9\u30c8\u30ec\u30b9\u4e0b\u3067\u306e\u5224\u65ad\u529b\u304c\u9ad8\u3044\u304c\u3001\u6301\u7d9a\u7684\u306a\u96c6\u4e2d\u304c\u96e3\u3057\u3044\u3002<\/li>\n\n\n\n<li><strong>Met\/Met\u578b<\/strong> \u2192 \u30c9\u30fc\u30d1\u30df\u30f3\u306e\u5206\u89e3\u304c\u9045\u304f\u3001\u96c6\u4e2d\u529b\u304c\u9ad8\u3044\u304c\u3001\u30b9\u30c8\u30ec\u30b9\u3092\u53d7\u3051\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u9069\u5207\u306a\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u65b9\u6cd5<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Val\/Val\u578b<\/strong> \u2192 \u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u7791\u60f3\u3084\u30b9\u30c8\u30ec\u30b9\u30de\u30cd\u30b8\u30e1\u30f3\u30c8\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u6d3b\u7528\u3002<\/li>\n\n\n\n<li><strong>Met\/Met\u578b<\/strong> \u2192 \u77ed\u6642\u9593\u306e\u30b9\u30c8\u30ec\u30b9\u8ca0\u8377\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u3001GABA\u3092\u5897\u3084\u3059\u98df\u54c1\uff08\u30ca\u30c3\u30c4\u3001\u767a\u9175\u98df\u54c1\uff09\u3092\u7a4d\u6975\u7684\u306b\u6442\u53d6\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>5. \u907a\u4f1d\u5b50\u3068\u7761\u7720\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5.1 CLOCK\u907a\u4f1d\u5b50\u3068\u6982\u65e5\u30ea\u30ba\u30e0<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"574\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/27034914_m-1024x574.jpg\" alt=\"\" class=\"wp-image-9091\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27034914_m-1024x574.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27034914_m-300x168.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27034914_m-768x430.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27034914_m-1536x861.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27034914_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u7761\u7720\u306e\u8cea\u3068\u907a\u4f1d\u5b50\u306e\u95a2\u4fc2\u306f\u6df1\u304f\u3001\u7279\u306b<strong>CLOCK\u907a\u4f1d\u5b50<\/strong>\u304c\u6982\u65e5\u30ea\u30ba\u30e0\uff08\u4f53\u5185\u6642\u8a08\uff09\u3092\u8abf\u7bc0\u3059\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2686937\/\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CLOCK\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u3042\u308b\u3068<\/strong>\u3001\u4e0d\u7720\u75c7\u3084\u6982\u65e5\u30ea\u30ba\u30e0\u7761\u7720\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u591c\u578b\u30bf\u30a4\u30d7\u306e\u907a\u4f1d\u5b50\u5909\u7570<\/strong> \u3092\u6301\u3064\u4eba\u306f\u3001\u81ea\u7136\u5149\u3092\u6d74\u3073\u308b\u6642\u9593\u3092\u5897\u3084\u3059\u3053\u3068\u3067\u7761\u7720\u306e\u8cea\u3092\u6539\u5584\u3067\u304d\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>5.2 PER3\u907a\u4f1d\u5b50\u3068\u7761\u7720\u306e\u9577\u3055<\/strong><\/h3>\n\n\n\n<p><strong>PER3\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u7761\u7720\u306e\u9577\u3055\u3084\u6df1\u3055\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/academic.oup.com\/sleep\/article\/33\/5\/695\/2454513\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u9577\u3044\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u2192 \u9577\u6642\u9593\u306e\u7761\u7720\u3092\u5fc5\u8981\u3068\u3057\u3001\u7761\u7720\u4e0d\u8db3\u306e\u5f71\u97ff\u3092\u5f37\u304f\u53d7\u3051\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>\u77ed\u3044\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u2192 \u77ed\u6642\u9593\u7761\u7720\u3067\u3082\u6bd4\u8f03\u7684\u5f71\u97ff\u3092\u53d7\u3051\u306b\u304f\u3044\u304c\u3001\u75b2\u52b4\u304c\u84c4\u7a4d\u3057\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u7761\u7720\u7ba1\u7406\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3084\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>6. \u907a\u4f1d\u5b50\u3068\u793e\u4f1a\u7684\u884c\u52d5<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>6.1 AVPR1A\u907a\u4f1d\u5b50\u3068\u5171\u611f\u529b<\/strong><\/h3>\n\n\n\n<p><strong>AVPR1A\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u30d0\u30bd\u30d7\u30ec\u30b7\u30f3\u3068\u3044\u3046\u30db\u30eb\u30e2\u30f3\u306e\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3057\u3001\u5171\u611f\u529b\u3084\u793e\u4f1a\u7684\u7d50\u3073\u3064\u304d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\uff08<a href=\"https:\/\/www.pnas.org\/content\/106\/45\/19169\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u793e\u4f1a\u7684\u76f8\u4e92\u4f5c\u7528\u3092\u597d\u307f\u3001\u5171\u611f\u529b\u304c\u9ad8\u3044\u3002<\/li>\n\n\n\n<li><strong>\u5225\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u793e\u4f1a\u7684\u306a\u95a2\u4fc2\u3092\u7bc9\u304f\u306e\u304c\u96e3\u3057\u304f\u3001\u5b64\u72ec\u3092\u611f\u3058\u3084\u3059\u3044\u50be\u5411\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u578b\u306b\u5fdc\u3058\u305f\u793e\u4f1a\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u53d6\u308b\u3053\u3068\u3067\u3001\u5e78\u798f\u611f\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>7. \u907a\u4f1d\u5b50\u3092\u6d3b\u7528\u3057\u305f\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2\u306e\u672a\u6765<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7.1 \u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u6d3b\u7528\u3057\u3001\u500b\u3005\u306e\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306e\u7279\u6027\u306b\u5408\u308f\u305b\u305f\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u7cbe\u795e\u7684\u306a\u5065\u5eb7\u3092\u6700\u9069\u5316\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u500b\u5225\u5316\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2\u306e\u4f8b<\/strong>\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30bb\u30ed\u30c8\u30cb\u30f3\u4f4e\u4e0b\u578b\uff085-HTTLPR S\u578b\uff09<\/strong> \u2192 \u6297\u3046\u3064\u85ac\u3001\u904b\u52d5\u7642\u6cd5\u3001\u30dd\u30b8\u30c6\u30a3\u30d6\u5fc3\u7406\u5b66\u306e\u6d3b\u7528\u3002<\/li>\n\n\n\n<li><strong>\u30c9\u30fc\u30d1\u30df\u30f3\u5831\u916c\u904e\u654f\u578b\uff08DRD4 7R\u578b\uff09<\/strong> \u2192 \u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u5411\u4e0a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u65b0\u3057\u3044\u4f53\u9a13\u306e\u7a4d\u6975\u7684\u306a\u5c0e\u5165\u3002<\/li>\n\n\n\n<li><strong>\u30b9\u30c8\u30ec\u30b9\u904e\u654f\u578b\uff08NR3C1\u9ad8\u767a\u73fe\uff09<\/strong> \u2192 \u30b3\u30eb\u30c1\u30be\u30fc\u30eb\u3092\u6291\u5236\u3059\u308b\u751f\u6d3b\u7fd2\u6163\u306e\u5c0e\u5165\uff08\u30e8\u30ac\u3001\u547c\u5438\u6cd5\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>7.2 AI\u3068\u907a\u4f1d\u5b50\u89e3\u6790\u306b\u3088\u308b\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/29272986_m-1024x683.jpg\" alt=\"\n\u30c7\u30fc\u30bf\u3084\u30b0\u30e9\u30d5\u3092\u8868\u793a\u3059\u308b\u30e2\u30cb\u30bf\u30fc\" class=\"wp-image-9800\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29272986_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29272986_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29272986_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29272986_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/29272986_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>AI\u3092\u6d3b\u7528\u3057\u305f\u907a\u4f1d\u5b50\u89e3\u6790\u6280\u8853\u304c\u9032\u5316\u3057\u3001\u7cbe\u795e\u75be\u60a3\u306e\u30ea\u30b9\u30af\u3092\u3088\u308a\u7cbe\u5bc6\u306b\u4e88\u6e2c\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<strong>\u30d3\u30c3\u30b0\u30c7\u30fc\u30bf\u3092\u6d3b\u7528\u3057\u305f\u907a\u4f1d\u5b50\u00d7\u74b0\u5883\u5206\u6790<\/strong> \u306b\u3088\u308a\u3001\u500b\u5225\u306e\u5e78\u798f\u5ea6\u3092\u6700\u5927\u5316\u3059\u308b\u30d7\u30ed\u30b0\u30e9\u30e0\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41562-020-01040-2\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u3068\u5fc3\u306e\u5065\u5eb7\u306e\u95a2\u4fc2\u3092\u7406\u89e3\u3057\u3001\u500b\u3005\u306e\u907a\u4f1d\u7684\u7279\u6027\u306b\u57fa\u3065\u3044\u305f\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2\u3092\u5b9f\u8df5\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u5e78\u798f\u306e\u8ffd\u6c42\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u4eca\u5f8c\u3001\u907a\u4f1d\u5b50\u6280\u8853\u306e\u767a\u5c55\u306b\u3088\u308a\u3001\u79d1\u5b66\u7684\u6839\u62e0\u306b\u57fa\u3065\u3044\u305f\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u304c\u666e\u53ca\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>8. \u907a\u4f1d\u5b50\u3068\u611f\u60c5\u8abf\u6574\u80fd\u529b<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>8.1 MAOA\u907a\u4f1d\u5b50\u3068\u6012\u308a\u30fb\u653b\u6483\u6027<\/strong><\/h3>\n\n\n\n<p><strong>MAOA\uff08\u30e2\u30ce\u30a2\u30df\u30f3\u30aa\u30ad\u30b7\u30c0\u30fc\u30bcA\uff09\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3067\u3042\u308b\u30bb\u30ed\u30c8\u30cb\u30f3\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306e\u5206\u89e3\u306b\u95a2\u4e0e\u3057\u3001\u611f\u60c5\u306e\u8abf\u6574\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002MAOA\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3001\u6012\u308a\u3084\u885d\u52d5\u6027\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/mp2009130\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>MAOA-L\uff08\u4f4e\u6d3b\u6027\u578b\uff09<\/strong> \u3092\u6301\u3064\u4eba\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u3084\u6311\u767a\u306b\u5bfe\u3057\u3066\u6012\u308a\u3084\u653b\u6483\u6027\u3092\u793a\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>MAOA-H\uff08\u9ad8\u6d3b\u6027\u578b\uff09<\/strong> \u3092\u6301\u3064\u4eba\u306f\u3001\u611f\u60c5\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u5b89\u5b9a\u3057\u3066\u304a\u308a\u3001\u51b7\u9759\u306a\u5224\u65ad\u304c\u3057\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>MAOA-L\u306e\u30bf\u30a4\u30d7\u3092\u6301\u3064\u4eba\u306f\u3001\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u306e\u305f\u3081\u306b<strong>\u30de\u30a4\u30f3\u30c9\u30d5\u30eb\u30cd\u30b9\u7791\u60f3\u3084\u611f\u60c5\u8a8d\u77e5\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0<\/strong>\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>8.2 GABRA2\u907a\u4f1d\u5b50\u3068\u4e0d\u5b89\u611f\u306e\u5f37\u3055<\/strong><\/h3>\n\n\n\n<p><strong>GABRA2\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u8133\u5185\u3067\u30ea\u30e9\u30c3\u30af\u30b9\u3092\u4fc3\u9032\u3059\u308bGABA\uff08\u03b3-\u30a2\u30df\u30ce\u916a\u9178\uff09\u306e\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306b\u3088\u3063\u3066\u3001\u4e0d\u5b89\u306e\u611f\u3058\u3084\u3059\u3055\u3084\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306b\u9055\u3044\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41398-018-0282-9\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30ea\u30b9\u30af\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u4e0d\u5b89\u969c\u5bb3\u3084\u30a2\u30eb\u30b3\u30fc\u30eb\u4f9d\u5b58\u75c7\u306b\u306a\u308a\u3084\u3059\u3044\u50be\u5411\u3002<\/li>\n\n\n\n<li><strong>\u975e\u30ea\u30b9\u30af\u578b\u306e\u4eba<\/strong> \u306f\u3001\u30b9\u30c8\u30ec\u30b9\u306b\u5f37\u304f\u3001\u4e0d\u5b89\u304c\u5c11\u306a\u3044\u50be\u5411\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u4e0d\u5b89\u611f\u304c\u5f37\u3044\u30bf\u30a4\u30d7\u306e\u4eba\u306f\u3001<strong>GABA\u3092\u5897\u3084\u3059\u98df\u54c1\uff08\u7dd1\u8336\u3001\u767a\u9175\u98df\u54c1\uff09<\/strong> \u3084<strong>\u30e8\u30ac\u30fb\u6df1\u547c\u5438\u306a\u3069\u306e\u30ea\u30e9\u30af\u30bc\u30fc\u30b7\u30e7\u30f3\u6cd5<\/strong>\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u611f\u60c5\u306e\u5b89\u5b9a\u3092\u4fc3\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>8.3 SLC6A4\u907a\u4f1d\u5b50\u3068\u6291\u3046\u3064\u30ea\u30b9\u30af<\/strong><\/h3>\n\n\n\n<p><strong>SLC6A4\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u3092\u30b3\u30fc\u30c9\u3057\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u518d\u5438\u53ce\u3092\u8abf\u6574\u3059\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3001\u3046\u3064\u75c5\u306e\u767a\u75c7\u30ea\u30b9\u30af\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u304f\u306e\u7814\u7a76\u3067\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/mp2013139\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u77ed\u3044\u30d0\u30ea\u30a2\u30f3\u30c8\uff08S\u578b\uff09\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u518d\u5438\u53ce\u304c\u4f4e\u4e0b\u3057\u3001\u30b9\u30c8\u30ec\u30b9\u306e\u5f71\u97ff\u3092\u53d7\u3051\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>\u9577\u3044\u30d0\u30ea\u30a2\u30f3\u30c8\uff08L\u578b\uff09\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u518d\u5438\u53ce\u304c\u30b9\u30e0\u30fc\u30ba\u3067\u3001\u6c17\u5206\u304c\u5b89\u5b9a\u3057\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>S\u578b\u3092\u6301\u3064\u4eba\u306f\u3001<strong>\u30bb\u30ed\u30c8\u30cb\u30f3\u3092\u5897\u3084\u3059\u98df\u4e8b\uff08\u30c8\u30ea\u30d7\u30c8\u30d5\u30a1\u30f3\u3092\u542b\u3080\u98df\u54c1\uff1a\u30d0\u30ca\u30ca\u3001\u30ca\u30c3\u30c4\u3001\u30c1\u30fc\u30ba\uff09<\/strong> \u3084<strong>\u65e5\u5149\u6d74\uff08\u30d3\u30bf\u30df\u30f3D\u306e\u751f\u6210\u3092\u4fc3\u9032\uff09<\/strong> \u3092\u610f\u8b58\u3059\u308b\u3068\u3088\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>9. \u907a\u4f1d\u5b50\u3068\u793e\u4f1a\u7684\u884c\u52d5<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>9.1 CD38\u907a\u4f1d\u5b50\u3068\u5171\u611f\u80fd\u529b<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/27532021_m-1024x768.jpg\" alt=\"\n\u4fdd\u80b2\u5712\u3067\u4ef2\u826f\u304f\u904a\u3076\u5712\u5150\u306e\u5f8c\u308d\u59ff\" class=\"wp-image-9807\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27532021_m-1024x768.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27532021_m-300x225.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27532021_m-768x576.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27532021_m-1536x1152.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27532021_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>CD38\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u306e\u5206\u6ccc\u3092\u8abf\u6574\u3057\u3001\u5171\u611f\u80fd\u529b\u3084\u793e\u4f1a\u7684\u95a2\u4fc2\u306e\u69cb\u7bc9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002CD38\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba\u306f\u3001\u4ed6\u8005\u3068\u306e\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u304c\u5f97\u610f\u3067\u3001\u793e\u4f1a\u7684\u306a\u30b5\u30dd\u30fc\u30c8\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u591a\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/mp201523\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CD38\u306e\u9ad8\u767a\u73fe\u578b<\/strong> \u2192 \u5171\u611f\u529b\u304c\u9ad8\u304f\u3001\u4ed6\u8005\u3068\u5f37\u3044\u7d46\u3092\u7bc9\u304d\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>CD38\u306e\u4f4e\u767a\u73fe\u578b<\/strong> \u2192 \u793e\u4ea4\u7684\u306a\u5834\u9762\u3067\u306e\u4e0d\u5b89\u304c\u5f37\u304f\u3001\u5b64\u72ec\u3092\u611f\u3058\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>CD38\u306e\u4f4e\u767a\u73fe\u578b\u306e\u4eba\u306f\u3001<strong>\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\u3092\u5897\u3084\u3059\u6d3b\u52d5\uff08\u30b9\u30ad\u30f3\u30b7\u30c3\u30d7\u3001\u30da\u30c3\u30c8\u3068\u306e\u3075\u308c\u3042\u3044\uff09<\/strong> \u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u793e\u4f1a\u7684\u5e78\u798f\u611f\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>9.2 VASOP\u907a\u4f1d\u5b50\u3068\u604b\u611b\u95a2\u4fc2<\/strong><\/h3>\n\n\n\n<p>\u30d0\u30bd\u30d7\u30ec\u30b7\u30f3\u306f\u3001\u604b\u611b\u95a2\u4fc2\u3084\u30d1\u30fc\u30c8\u30ca\u30fc\u30b7\u30c3\u30d7\u306e\u7dad\u6301\u306b\u95a2\u4e0e\u3059\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308a\u3001\u305d\u306e\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3059\u308b<strong>VASOP\u907a\u4f1d\u5b50<\/strong>\u306f\u3001\u604b\u611b\u30b9\u30bf\u30a4\u30eb\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41598-017-15122-9\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u30d1\u30fc\u30c8\u30ca\u30fc\u3078\u306e\u5fe0\u8aa0\u5fc3\u304c\u9ad8\u304f\u3001\u5b89\u5b9a\u3057\u305f\u95a2\u4fc2\u3092\u7bc9\u304d\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>\u5225\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u6d6e\u6c17\u3084\u95a2\u4fc2\u306e\u4e0d\u5b89\u5b9a\u3055\u3068\u95a2\u9023\u3059\u308b\u50be\u5411\u304c\u3042\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u30d1\u30fc\u30c8\u30ca\u30fc\u30b7\u30c3\u30d7\u3092\u5f37\u5316\u3059\u308b\u305f\u3081\u306b\u306f\u3001<strong>\u30d0\u30bd\u30d7\u30ec\u30b7\u30f3\u3092\u5897\u3084\u3059\u751f\u6d3b\u7fd2\u6163\uff08\u898f\u5247\u7684\u306a\u7761\u7720\u3001\u7791\u60f3\u3001\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\uff09<\/strong> \u3092\u610f\u8b58\u3059\u308b\u3068\u3088\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>10. \u907a\u4f1d\u5b50\u3068\u5275\u9020\u6027\u30fb\u77e5\u6027<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>10.1 DARPP-32\u907a\u4f1d\u5b50\u3068\u5275\u9020\u6027<\/strong><\/h3>\n\n\n\n<p><strong>DARPP-32\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u524d\u982d\u524d\u91ce\u306e\u50cd\u304d\u3092\u8abf\u6574\u3057\u3001\u5275\u9020\u6027\u3084\u554f\u984c\u89e3\u6c7a\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u5275\u9020\u7684\u601d\u8003\u306e\u767a\u9054\u306b\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41562-020-00993-6\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u65b0\u3057\u3044\u30a2\u30a4\u30c7\u30a2\u3092\u751f\u307f\u51fa\u3059\u80fd\u529b\u304c\u9ad8\u304f\u3001\u5275\u9020\u7684\u6d3b\u52d5\u306b\u9069\u3057\u3066\u3044\u308b\u3002<\/li>\n\n\n\n<li><strong>\u5225\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u8ad6\u7406\u7684\u601d\u8003\u3084\u4f53\u7cfb\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u5f97\u610f\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u5275\u9020\u6027\u3092\u9ad8\u3081\u308b\u305f\u3081\u306b\u306f\u3001<strong>\u30a2\u30fc\u30c8\u3084\u97f3\u697d\u3001\u7791\u60f3\u3092\u53d6\u308a\u5165\u308c\u305f\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb<\/strong> \u304c\u6709\u52b9\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>10.2 CHRM2\u907a\u4f1d\u5b50\u3068\u77e5\u80fd<\/strong><\/h3>\n\n\n\n<p><strong>CHRM2\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u30b7\u30ca\u30d7\u30b9\u306e\u53ef\u5851\u6027\u3084\u5b66\u7fd2\u80fd\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u306f\u3001\u77e5\u80fd\u30c6\u30b9\u30c8\u306e\u30b9\u30b3\u30a2\u3068\u95a2\u9023\u304c\u3042\u308b\u3068\u3055\u308c\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/ng1536\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u8a18\u61b6\u529b\u3084\u60c5\u5831\u51e6\u7406\u80fd\u529b\u304c\u9ad8\u3044\u50be\u5411\u3002<\/li>\n\n\n\n<li><strong>\u5225\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u76f4\u611f\u7684\u306a\u5224\u65ad\u304c\u5f97\u610f\u3067\u3001\u5373\u8208\u7684\u306a\u601d\u8003\u304c\u5f97\u610f\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u77e5\u80fd\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u305f\u3081\u306b\u306f\u3001<strong>\u5b66\u7fd2\u306e\u591a\u69d8\u5316\uff08\u8aad\u66f8\u3001\u8a00\u8a9e\u5b66\u7fd2\u3001\u8ad6\u7406\u30d1\u30ba\u30eb\uff09<\/strong> \u304c\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u306f\u79c1\u305f\u3061\u306e\u5fc3\u306e\u5065\u5eb7\u3001\u611f\u60c5\u306e\u8abf\u6574\u3001\u793e\u4f1a\u7684\u884c\u52d5\u3001\u5275\u9020\u6027\u3001\u77e5\u6027\u306a\u3069\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u307e\u3059\u3002\u500b\u3005\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u7406\u89e3\u3057\u3001\u305d\u308c\u306b\u57fa\u3065\u3044\u305f\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u5145\u5b9f\u3057\u305f\u4eba\u751f\u3092\u9001\u308b\u305f\u3081\u306e\u79d1\u5b66\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>11. \u907a\u4f1d\u5b50\u3068\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\uff1a\u610f\u6b32\u3092\u5de6\u53f3\u3059\u308b\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"585\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/31845747_m-1024x585.jpg\" alt=\"\n\u52c9\u5f37\u3059\u308b\u5b50\u4f9b\u306e\u624b\u5143\u3000\u5c0f\u5b66\u751f\" class=\"wp-image-9814\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31845747_m-1024x585.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31845747_m-300x171.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31845747_m-768x439.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31845747_m-1536x878.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/31845747_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>11.1 TH\u907a\u4f1d\u5b50\u3068\u30c9\u30fc\u30d1\u30df\u30f3\u751f\u6210<\/strong><\/h3>\n\n\n\n<p><strong>TH\uff08\u30c1\u30ed\u30b7\u30f3\u30d2\u30c9\u30ed\u30ad\u30b7\u30e9\u30fc\u30bc\uff09\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u751f\u6210\u306b\u95a2\u4e0e\u3057\u3001\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u3084\u610f\u6b32\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u30c9\u30fc\u30d1\u30df\u30f3\u306f\u5831\u916c\u7cfb\u306e\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3067\u3042\u308a\u3001\u76ee\u6a19\u9054\u6210\u3078\u306e\u610f\u6b32\u3084\u5b66\u7fd2\u610f\u6b32\u306e\u5411\u4e0a\u306b\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41380-020-0679-7\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>TH\u907a\u4f1d\u5b50\u306e\u9ad8\u767a\u73fe\u578b<\/strong> \u3092\u6301\u3064\u4eba\u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u751f\u6210\u91cf\u304c\u591a\u304f\u3001\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u304c\u9ad8\u304f\u7dad\u6301\u3055\u308c\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>TH\u907a\u4f1d\u5b50\u306e\u4f4e\u767a\u73fe\u578b<\/strong> \u3092\u6301\u3064\u4eba\u306f\u3001\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u304c\u4f4e\u4e0b\u3057\u3084\u3059\u304f\u3001\u9054\u6210\u611f\u3092\u5f97\u308b\u307e\u3067\u306e\u6642\u9593\u304c\u9577\u3044\u50be\u5411\u304c\u3042\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u304c\u4f4e\u767a\u73fe\u306e\u4eba\u306f\u3001<strong>\u904b\u52d5\uff08\u7279\u306b\u30a6\u30a9\u30fc\u30ad\u30f3\u30b0\u3084\u30e9\u30f3\u30cb\u30f3\u30b0\uff09<\/strong> \u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u30c9\u30fc\u30d1\u30df\u30f3\u751f\u6210\u3092\u4fc3\u9032\u3057\u3001\u610f\u6b32\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>11.2 DAT1\u907a\u4f1d\u5b50\u3068\u96c6\u4e2d\u529b<\/strong><\/h3>\n\n\n\n<p><strong>DAT1\uff08\u30c9\u30fc\u30d1\u30df\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u907a\u4f1d\u5b50\uff09<\/strong> \u306f\u3001\u8133\u5185\u3067\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u518d\u5438\u53ce\u3092\u5236\u5fa1\u3057\u3001\u6ce8\u610f\u529b\u3084\u96c6\u4e2d\u529b\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41398-018-0233-5\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>DAT1 10\u30ea\u30d4\u30fc\u30c8\u578b\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u306e\u518d\u5438\u53ce\u304c\u6d3b\u767a\u3067\u3001\u96c6\u4e2d\u529b\u304c\u7d9a\u304d\u306b\u304f\u3044\u3002<\/li>\n\n\n\n<li><strong>DAT1 9\u30ea\u30d4\u30fc\u30c8\u578b\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u30c9\u30fc\u30d1\u30df\u30f3\u304c\u9577\u304f\u6301\u7d9a\u3057\u3001\u6ce8\u610f\u529b\u304c\u9ad8\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u96c6\u4e2d\u529b\u3092\u5411\u4e0a\u3055\u305b\u308b\u305f\u3081\u306b\u306f\u3001<strong>\u30ab\u30d5\u30a7\u30a4\u30f3\u6442\u53d6\u3084\u77ed\u6642\u9593\u306e\u96c6\u4e2d\u4f5c\u696d\uff08\u30dd\u30e2\u30c9\u30fc\u30ed\u30fb\u30c6\u30af\u30cb\u30c3\u30af\uff09<\/strong> \u3092\u6d3b\u7528\u3059\u308b\u3068\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>11.3 DRD2\u907a\u4f1d\u5b50\u3068\u52aa\u529b\u306e\u7d99\u7d9a<\/strong><\/h3>\n\n\n\n<p><strong>DRD2\uff08\u30c9\u30fc\u30d1\u30df\u30f3D2\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\uff09<\/strong> \u306f\u3001\u5831\u916c\u7cfb\u306e\u611f\u53d7\u6027\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u52aa\u529b\u306e\u7d99\u7d9a\u529b\u3092\u6c7a\u5b9a\u3059\u308b\u8981\u56e0\u306e\u4e00\u3064\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41598-018-35399-9\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>DRD2\u306e\u7279\u5b9a\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u9577\u671f\u7684\u306a\u5831\u916c\u3092\u6c42\u3081\u3066\u52aa\u529b\u3092\u7d99\u7d9a\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>\u5225\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u77ed\u671f\u7684\u306a\u5831\u916c\u3092\u6c42\u3081\u308b\u50be\u5411\u304c\u5f37\u304f\u3001\u9014\u4e2d\u3067\u8ae6\u3081\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u6027\u306b\u5fdc\u3058\u305f\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u7ba1\u7406\u3068\u3057\u3066\u3001<strong>\u77ed\u671f\u76ee\u6a19\u3092\u7d30\u304b\u304f\u8a2d\u5b9a\u3059\u308b\u65b9\u6cd5\uff08\u30b9\u30e2\u30fc\u30eb\u30a6\u30a3\u30f3\u7406\u8ad6\uff09<\/strong> \u304c\u6709\u52b9\u3067\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>12. \u907a\u4f1d\u5b50\u3068\u30ea\u30b9\u30af\u9078\u597d\uff1a\u5192\u967a\u5fc3\u3092\u6c7a\u3081\u308b\u907a\u4f1d\u7684\u8981\u56e0<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>12.1 DRD4\u907a\u4f1d\u5b50\u3068\u30ea\u30b9\u30af\u30c6\u30a4\u30af\u50be\u5411<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"574\" src=\"\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-1024x574.jpg\" alt=\"\n\u79cb\u306e\u5c71\u3068\u65e5\u672c\u4eba\u306e\u7537\u306e\u5b50\" class=\"wp-image-9821\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-1024x574.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-300x168.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-768x430.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m-1536x861.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2025\/03\/27099504_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><strong>DRD4\uff08\u30c9\u30fc\u30d1\u30df\u30f3D4\u53d7\u5bb9\u4f53\u907a\u4f1d\u5b50\uff09<\/strong> \u306f\u3001\u30ea\u30b9\u30af\u9078\u597d\u3084\u5192\u967a\u5fc3\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u7279\u306b<strong>7R\u30d0\u30ea\u30a2\u30f3\u30c8<\/strong> \u3092\u6301\u3064\u4eba\u306f\u3001\u65b0\u3057\u3044\u7d4c\u9a13\u3092\u6c42\u3081\u308b\u50be\u5411\u304c\u5f37\u3044\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41598-017-18264-w\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>DRD4 7R\u578b\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u65b0\u3057\u3044\u4f53\u9a13\u3092\u597d\u307f\u3001\u30ea\u30b9\u30af\u3092\u53d6\u308b\u884c\u52d5\u3092\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>DRD4 4R\u4ee5\u4e0b\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u5b89\u5168\u5fd7\u5411\u304c\u5f37\u304f\u3001\u614e\u91cd\u306a\u9078\u629e\u3092\u3059\u308b\u50be\u5411\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u30ea\u30b9\u30af\u9078\u597d\u3092\u6d3b\u304b\u3057\u305f\u30ad\u30e3\u30ea\u30a2\u9078\u629e\u3084\u6295\u8cc7\u6226\u7565\u3092\u8003\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>12.2 5-HTTLPR\u907a\u4f1d\u5b50\u3068\u4e0d\u78ba\u5b9f\u6027\u8010\u6027<\/strong><\/h3>\n\n\n\n<p><strong>5-HTTLPR\uff08\u30bb\u30ed\u30c8\u30cb\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc\u907a\u4f1d\u5b50\uff09<\/strong> \u306f\u3001\u4e0d\u78ba\u5b9f\u6027\u306b\u5bfe\u3059\u308b\u8010\u6027\u3084\u30ea\u30b9\u30af\u9078\u597d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41562-018-0419-2\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>L\u578b\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u4e0d\u78ba\u5b9f\u306a\u72b6\u6cc1\u3067\u3082\u51b7\u9759\u306b\u5bfe\u5fdc\u3057\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>S\u578b\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u4e0d\u78ba\u5b9f\u6027\u306b\u5bfe\u3057\u3066\u5f37\u3044\u30b9\u30c8\u30ec\u30b9\u3092\u611f\u3058\u3084\u3059\u3044\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u6027\u3092\u6d3b\u304b\u3057\u3001<strong>S\u578b\u306e\u4eba\u306f\u4e0d\u78ba\u5b9f\u6027\u3092\u6e1b\u3089\u3059\u305f\u3081\u306e\u60c5\u5831\u53ce\u96c6\u3092\u5fb9\u5e95\u3059\u308b<\/strong> \u306a\u3069\u306e\u5bfe\u5fdc\u7b56\u3092\u8b1b\u3058\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>13. \u907a\u4f1d\u5b50\u3068\u5b66\u7fd2\u80fd\u529b\uff1a\u60c5\u5831\u51e6\u7406\u306e\u30b9\u30d4\u30fc\u30c9\u3068\u8a18\u61b6\u529b<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>13.1 CHRM2\u907a\u4f1d\u5b50\u3068\u8a18\u61b6\u529b<\/strong><\/h3>\n\n\n\n<p><strong>CHRM2\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u8a8d\u77e5\u6a5f\u80fd\u3084\u8a18\u61b6\u529b\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u8a18\u61b6\u529b\u306e\u5411\u4e0a\u3068\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/ng1536\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u9577\u671f\u8a18\u61b6\u304c\u5f37\u304f\u3001\u65b0\u3057\u3044\u60c5\u5831\u3092\u7d20\u65e9\u304f\u7fd2\u5f97\u3067\u304d\u308b\u3002<\/li>\n\n\n\n<li><strong>\u5225\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u3092\u6301\u3064\u4eba<\/strong> \u306f\u3001\u77ed\u671f\u8a18\u61b6\u304c\u5f97\u610f\u3067\u3001\u5373\u8208\u7684\u306a\u5224\u65ad\u529b\u306b\u512a\u308c\u308b\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u5b66\u7fd2\u52b9\u679c\u3092\u9ad8\u3081\u308b\u305f\u3081\u306b\u306f\u3001<strong>\u7761\u7720\u306e\u8cea\u3092\u5411\u4e0a\u3055\u305b\u3001\u8a18\u61b6\u306e\u5b9a\u7740\u3092\u4fc3\u3059<\/strong> \u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>13.2 FOXP2\u907a\u4f1d\u5b50\u3068\u8a00\u8a9e\u80fd\u529b<\/strong><\/h3>\n\n\n\n<p><strong>FOXP2\u907a\u4f1d\u5b50<\/strong> \u306f\u3001\u8a00\u8a9e\u80fd\u529b\u3084\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u80fd\u529b\u306b\u95a2\u4e0e\u3057\u3001\u7279\u5b9a\u306e\u30d0\u30ea\u30a2\u30f3\u30c8\u304c\u8a00\u8a9e\u7fd2\u5f97\u80fd\u529b\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08<a href=\"https:\/\/www.nature.com\/articles\/s41598-018-28334-5\">\u53c2\u8003\u7814\u7a76<\/a>\uff09\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>FOXP2\u306e\u767a\u73fe\u304c\u9ad8\u3044\u4eba<\/strong> \u306f\u3001\u8a9e\u5b66\u7fd2\u5f97\u304c\u65e9\u304f\u3001\u767a\u97f3\u304c\u6b63\u78ba\u306b\u306a\u308a\u3084\u3059\u3044\u3002<\/li>\n\n\n\n<li><strong>FOXP2\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba<\/strong> \u306f\u3001\u8a00\u8a9e\u7fd2\u5f97\u306b\u6642\u9593\u304c\u304b\u304b\u308b\u304c\u3001\u8ad6\u7406\u7684\u601d\u8003\u529b\u304c\u5f37\u3044\u50be\u5411\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u306e\u7279\u6027\u3092\u7406\u89e3\u3057\u3001<strong>FOXP2\u306e\u767a\u73fe\u304c\u4f4e\u3044\u4eba\u306f\u8996\u899a\u7684\u5b66\u7fd2\uff08\u30d5\u30e9\u30c3\u30b7\u30e5\u30ab\u30fc\u30c9\uff09<\/strong> \u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u5b66\u7fd2\u52b9\u7387\u3092\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u306f\u79c1\u305f\u3061\u306e\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3\u3001\u30ea\u30b9\u30af\u9078\u597d\u3001\u5b66\u7fd2\u80fd\u529b\u306b\u307e\u3067\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u307e\u3059\u3002\u500b\u3005\u306e\u907a\u4f1d\u7684\u7279\u6027\u3092\u7406\u89e3\u3057\u3001\u305d\u308c\u306b\u9069\u3057\u305f\u6226\u7565\u3092\u5b9f\u8df5\u3059\u308b\u3053\u3068\u3067\u3001\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u79d1\u5b66\u7684\u77e5\u898b\u306b\u57fa\u3065\u3044\u305f\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u3001\u3088\u308a\u826f\u3044\u81ea\u5df1\u6210\u9577\u3084\u30ad\u30e3\u30ea\u30a2\u5f62\u6210\u306b\u3064\u306a\u304c\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-c3e311fd-7fff-13df-e99f-e45baab858c0\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<p><strong>\u307e\u3068\u3081<\/strong><\/p>\n\n\n\n<p>\u5fc3\u306e\u5065\u5eb7\u3084\u5e78\u798f\u611f\u306f\u3001\u74b0\u5883\u8981\u56e0\u3060\u3051\u3067\u306a\u304f\u3001<strong>5-HTTLPR\uff08\u30bb\u30ed\u30c8\u30cb\u30f3\uff09\u3001DRD4\uff08\u30c9\u30fc\u30d1\u30df\u30f3\uff09\u3001OXTR\uff08\u30aa\u30ad\u30b7\u30c8\u30b7\u30f3\uff09<\/strong> \u306a\u3069\u306e\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u3082\u5f71\u97ff\u3092\u53d7\u3051\u307e\u3059\u3002<strong>\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3001\u5171\u611f\u529b\u3001\u30e2\u30c1\u30d9\u30fc\u30b7\u30e7\u30f3<\/strong> \u306a\u3069\u3082\u907a\u4f1d\u7684\u8981\u56e0\u3067\u6c7a\u307e\u308a\u3001\u500b\u3005\u306e\u907a\u4f1d\u578b\u306b\u5fdc\u3058\u305f\u30e1\u30f3\u30bf\u30eb\u30b1\u30a2\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u907a\u4f1d\u5b50\u60c5\u5831\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001<strong>\u9069\u5207\u306a\u904b\u52d5\u30fb\u98df\u4e8b\u30fb\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u6cd5<\/strong> \u3092\u9078\u629e\u3057\u3001\u3088\u308a\u9ad8\u3044\u5e78\u798f\u611f\u3068\u7cbe\u795e\u7684\u5065\u5eb7\u3092\u5b9f\u73fe\u3067\u304d\u307e\u3059\u3002\u79d1\u5b66\u7684\u77e5\u898b\u306b\u57fa\u3065\u304f\u500b\u5225\u6700\u9069\u5316\u304c\u3001\u4eca\u5f8c\u306e\u30e1\u30f3\u30bf\u30eb\u30d8\u30eb\u30b9\u306e\u9375\u3068\u306a\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4eba\u9593\u306e\u5e78\u798f\u3084\u5fc3\u306e\u5065\u5eb7\u306f\u3001\u74b0\u5883\u8981\u56e0\u3060\u3051\u3067\u306a\u304f\u3001\u907a\u4f1d\u7684\u8981\u56e0\u306b\u3088\u3063\u3066\u3082\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u306f\u3001\u907a\u4f1d\u5b50\u304c\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u3001\u6c17\u5206\u306e\u5b89\u5b9a\u3001\u793e\u4f1a\u6027\u3001\u5171\u611f\u529b\u3001\u3055\u3089\u306b\u306f\u5e78\u798f\u611f\u305d\u306e\u3082\u306e\u306b\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002 \u8133\u5185\u306e\u795e\u7d4c [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":9786,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-9785","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-technology"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/9785","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/comments?post=9785"}],"version-history":[{"count":1,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/9785\/revisions"}],"predecessor-version":[{"id":9828,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/9785\/revisions\/9828"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media\/9786"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media?parent=9785"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/categories?post=9785"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/tags?post=9785"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}