{"id":983,"date":"2024-12-18T04:32:59","date_gmt":"2024-12-18T04:32:59","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/gene\/?p=983"},"modified":"2025-01-27T03:15:44","modified_gmt":"2025-01-27T03:15:44","slug":"%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e3%82%a2%e3%83%ac%e3%83%ab%e3%82%ae%e3%83%bc%ef%bc%9a%e4%bd%93%e8%b3%aa%e3%81%ae%e9%81%95%e3%81%84%e3%81%a8%e3%81%9d%e3%81%ae%e5%85%8b%e6%9c%8d%e6%b3%95","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/gene\/%e9%81%ba%e4%bc%9d%e5%ad%90%e3%81%a8%e3%82%a2%e3%83%ac%e3%83%ab%e3%82%ae%e3%83%bc%ef%bc%9a%e4%bd%93%e8%b3%aa%e3%81%ae%e9%81%95%e3%81%84%e3%81%a8%e3%81%9d%e3%81%ae%e5%85%8b%e6%9c%8d%e6%b3%95\/","title":{"rendered":"\u907a\u4f1d\u5b50\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\uff1a\u4f53\u8cea\u306e\u9055\u3044\u3068\u305d\u306e\u514b\u670d\u6cd5"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u306f\u3001\u514d\u75ab\u7cfb\u304c\u7279\u5b9a\u306e\u7269\u8cea\u306b\u904e\u5270\u53cd\u5fdc\u3059\u308b\u3053\u3068\u3067\u5f15\u304d\u8d77\u3053\u3055\u308c\u307e\u3059\u3002\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u7684\u8981\u56e0\u304c\u8907\u96d1\u306b\u7d61\u307f\u5408\u3044\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u3002\u7279\u306b\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u3092\u4f5c\u308a\u51fa\u3059\u91cd\u8981\u306a\u8981\u56e0\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u907a\u4f1d\u7684\u306a\u5f71\u97ff\u306f\u3001\u89aa\u304b\u3089\u5b50\u3078\u53d7\u3051\u7d99\u304c\u308c\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u3001\u5bb6\u65cf\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u60a3\u8005\u304c\u3044\u308b\u5834\u5408\u3001\u305d\u306e\u5b50\u4f9b\u3082\u30a2\u30ec\u30eb\u30ae\u30fc\u3092\u767a\u75c7\u3059\u308b\u78ba\u7387\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u3067\u306f\u3001\u5177\u4f53\u7684\u306b\u3069\u306e\u907a\u4f1d\u5b50\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. FLG\u907a\u4f1d\u5b50\uff1a\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3068\u306e\u95a2\u9023<\/strong><\/h3>\n\n\n\n<p>FLG\uff08\u30d5\u30a3\u30e9\u30b0\u30ea\u30f3\uff09\u907a\u4f1d\u5b50\u306f\u3001\u76ae\u819a\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u76ae\u819a\u306e\u4fdd\u6e7f\u80fd\u529b\u304c\u4f4e\u4e0b\u3057\u3001\u5916\u90e8\u304b\u3089\u30a2\u30ec\u30eb\u30b2\u30f3\u304c\u4fb5\u5165\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3084\u5598\u606f\u3001\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>: \u65e5\u672c\u76ae\u819a\u79d1\u5b66\u4f1a &#8211; \u30d5\u30a3\u30e9\u30b0\u30ea\u30f3\u907a\u4f1d\u5b50\u3068\u30a2\u30ec\u30eb\u30ae\u30fc<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. IL4R\u907a\u4f1d\u5b50\u3068\u514d\u75ab\u5fdc\u7b54\u306e\u5909\u5316<\/strong><\/h3>\n\n\n\n<p>IL4R\u907a\u4f1d\u5b50\u306f\u3001\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3-4\u53d7\u5bb9\u4f53\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u514d\u75ab\u5fdc\u7b54\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306f\u3001IgE\u6297\u4f53\u306e\u7523\u751f\u3092\u4fc3\u9032\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001IL4R\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3001\u5598\u606f\u3084\u82b1\u7c89\u75c7\u306e\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306f\u3001\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u304c\u3069\u306e\u3088\u3046\u306b\u30a2\u30ec\u30eb\u30b2\u30f3\u306b\u53cd\u5fdc\u3059\u308b\u304b\u3092\u76f4\u63a5\u7684\u306b\u5236\u5fa1\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\"> PubMed &#8211; IL4R\u3068\u5598\u606f\u306e\u95a2\u4fc2<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. HLA\u907a\u4f1d\u5b50\u3068\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc<\/strong><\/h3>\n\n\n\n<p>HLA\uff08\u30d2\u30c8\u767d\u8840\u7403\u6297\u539f\uff09\u907a\u4f1d\u5b50\u306f\u3001\u514d\u75ab\u7cfb\u306e\u75c5\u539f\u4f53\u8a8d\u8b58\u3092\u52a9\u3051\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u591a\u578b\u304c\u3001\u7279\u5b9a\u306e\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u611f\u53d7\u6027\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u30a2\u30ec\u30eb\u30ae\u30fc\u3084\u5c0f\u9ea6\u30a2\u30ec\u30eb\u30ae\u30fc\u306f\u7279\u5b9a\u306eHLA\u907a\u4f1d\u5b50\u578b\u3068\u5f37\u304f\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.allergology.jp\"> \u30a2\u30ec\u30eb\u30ae\u30fc\u5b66\u4f1a &#8211; HLA\u3068\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc<\/a><\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u74b0\u5883\u8981\u56e0\u3068\u907a\u4f1d\u5b50\u306e\u76f8\u4e92\u4f5c\u7528<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u4e00\u65b9\u3067\u3001\u74b0\u5883\u8981\u56e0\u304c\u305d\u306e\u767a\u75c7\u3092\u52a0\u901f\u307e\u305f\u306f\u6291\u5236\u3059\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u76f8\u4e92\u4f5c\u7528\u304c\u3001\u540c\u3058\u907a\u4f1d\u5b50\u3092\u6301\u3064\u4eba\u3005\u306e\u9593\u3067\u3082\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u306b\u9055\u3044\u3092\u751f\u307f\u51fa\u3059\u7406\u7531\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u90fd\u5e02\u5316\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u5897\u52a0<\/strong><\/h3>\n\n\n\n<p>\u90fd\u5e02\u90e8\u3067\u306f\u3001\u7a7a\u6c17\u6c5a\u67d3\u3084\u5fae\u5c0f\u7c92\u5b50\u72b6\u7269\u8cea\uff08PM2.5\uff09\u304c\u514d\u75ab\u7cfb\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u907a\u4f1d\u7684\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u3092\u6301\u3064\u4eba\u3005\u306e\u75c7\u72b6\u3092\u60aa\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u8178\u5185\u7d30\u83cc\u53e2\u306e\u5909\u5316<\/strong><\/h3>\n\n\n\n<p>\u8178\u5185\u74b0\u5883\u3082\u30a2\u30ec\u30eb\u30ae\u30fc\u3068\u5bc6\u63a5\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u4eba\u304c\u3001\u8178\u5185\u7d30\u83cc\u53e2\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u5d29\u3059\u3068\u3001\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u304c\u904e\u654f\u306b\u53cd\u5fdc\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u8fd1\u5e74\u3001\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3092\u7528\u3044\u305f\u6cbb\u7642\u6cd5\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.microbiota.org\"> Gut Microbiota and Allergies &#8211; \u56fd\u969b\u5fae\u751f\u7269\u5b66\u4f1a<\/a><\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306e\u514b\u670d\u6cd5<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"768\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/24145813_m-1024x768.jpg\" alt=\"\u304f\u3057\u3083\u307f\u3000\u7537\u6027\" class=\"wp-image-2872\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24145813_m-1024x768.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24145813_m-300x225.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24145813_m-768x576.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24145813_m-1536x1152.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24145813_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u8a3a\u65ad\u3092\u6d3b\u7528\u3059\u308b<\/strong><\/h3>\n\n\n\n<p>\u8fd1\u5e74\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u6280\u8853\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u30ea\u30b9\u30af\u907a\u4f1d\u5b50\u3092\u7279\u5b9a\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u306e\u60c5\u5831\u3092\u57fa\u306b\u3001\u98df\u751f\u6d3b\u3084\u74b0\u5883\u8981\u56e0\u306e\u8abf\u6574\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u65b9\u6cd5\u304c\u63d0\u6848\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u500b\u5225\u5316\u533b\u7642\u3068\u514d\u75ab\u7642\u6cd5<\/strong><\/h3>\n\n\n\n<p>\u514d\u75ab\u7642\u6cd5\u306f\u3001\u7279\u5b9a\u306e\u30a2\u30ec\u30eb\u30b2\u30f3\u306b\u5bfe\u3059\u308b\u8010\u6027\u3092\u3064\u304f\u308b\u6cbb\u7642\u6cd5\u3067\u3042\u308a\u3001\u907a\u4f1d\u7684\u306a\u8981\u56e0\u3092\u8003\u616e\u3057\u305f\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u6709\u52b9\u3067\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u76ae\u4e0b\u514d\u75ab\u7642\u6cd5\u3084\u820c\u4e0b\u514d\u75ab\u7642\u6cd5\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u60a3\u8005\u306b\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u74b0\u5883\u306e\u6700\u9069\u5316<\/strong><\/h3>\n\n\n\n<p>\u907a\u4f1d\u5b50\u5909\u7570\u304c\u3042\u308b\u5834\u5408\u3067\u3082\u3001\u74b0\u5883\u306e\u6574\u5099\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u7de9\u548c\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30c0\u30cb\u3084\u30db\u30b3\u30ea\u3092\u6e1b\u3089\u3059\u305f\u3081\u306e\u7a7a\u6c17\u6e05\u6d44\u6a5f\u306e\u5229\u7528\u3084\u3001\u9069\u5207\u306a\u6e7f\u5ea6\u7ba1\u7406\u304c\u6709\u52b9\u3067\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u5909\u7570\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306e\u5177\u4f53\u4f8b<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u5909\u7570\u304c\u95a2\u4e0e\u3059\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306b\u306f\u3001\u591a\u304f\u306e\u5177\u4f53\u4f8b\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u4ee3\u8868\u7684\u306a\u75be\u60a3\u3092\u3044\u304f\u3064\u304b\u6319\u3052\u3001\u305d\u308c\u305e\u308c\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u3092\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306f\u3001\u5b50\u4f9b\u304b\u3089\u5927\u4eba\u307e\u3067\u5e45\u5e83\u3044\u5e74\u4ee3\u306b\u898b\u3089\u308c\u308b\u6162\u6027\u7684\u306a\u76ae\u819a\u75be\u60a3\u3067\u3059\u3002\u3053\u306e\u75be\u60a3\u306b\u306f\u3001<strong>FLG\u907a\u4f1d\u5b50<\/strong>\u4ee5\u5916\u306b\u3082\u591a\u304f\u306e\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001<strong>SPINK5\u907a\u4f1d\u5b50<\/strong>\u306f\u76ae\u819a\u30d0\u30ea\u30a2\u3092\u4fdd\u3064\u305f\u3081\u306b\u91cd\u8981\u306a\u9175\u7d20\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u76ae\u819a\u306e\u4fdd\u8b77\u80fd\u529b\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3084\u5598\u606f\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001<strong>IL13\u907a\u4f1d\u5b50<\/strong>\u306f\u708e\u75c7\u53cd\u5fdc\u306b\u95a2\u4e0e\u3057\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u60aa\u5316\u306b\u5bc4\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.atopy-foundation.org\"> \u30a2\u30c8\u30d4\u30fc\u7814\u7a76\u8ca1\u56e3<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u5598\u606f\u3068\u907a\u4f1d\u7684\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>\u5598\u606f\u306f\u3001\u6c17\u9053\u306e\u708e\u75c7\u3068\u72ed\u7a84\u3092\u7279\u5fb4\u3068\u3059\u308b\u75be\u60a3\u3067\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u5598\u606f\u306b\u95a2\u9023\u3059\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50\u306e\u4e00\u3064\u304c\u3001<strong>ADAM33\u907a\u4f1d\u5b50<\/strong>\u3067\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306f\u6c17\u9053\u306e\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\uff08\u69cb\u9020\u5909\u5316\uff09\u306b\u95a2\u4e0e\u3057\u3001\u7279\u5b9a\u306e\u5909\u7570\u304c\u3042\u308b\u3068\u6c17\u9053\u306e\u904e\u654f\u6027\u304c\u9ad8\u307e\u308a\u3001\u5598\u606f\u767a\u75c7\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001<strong>ORMDL3\u907a\u4f1d\u5b50<\/strong>\u3082\u5598\u606f\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306f\u3001\u6c17\u9053\u306e\u708e\u75c7\u3092\u8abf\u7bc0\u3059\u308b\u91cd\u8981\u306a\u56e0\u5b50\u3067\u3042\u308a\u3001\u6b27\u7c73\u3084\u30a2\u30b8\u30a2\u3092\u542b\u3080\u3055\u307e\u3056\u307e\u306a\u96c6\u56e3\u3067\u5598\u606f\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.asthma-genetics.jp\"> \u56fd\u7acb\u5598\u606f\u5b66\u4f1a &#8211; \u907a\u4f1d\u5b50\u7814\u7a76<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306f\u3001\u7279\u5b9a\u306e\u98df\u7269\u3092\u6442\u53d6\u3057\u305f\u969b\u306b\u904e\u5270\u306a\u514d\u75ab\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3059\u75be\u60a3\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u30a2\u30ec\u30eb\u30ae\u30fc\u306f\u3001<strong>CD14\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u3068\u95a2\u9023\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306f\u3001\u514d\u75ab\u7d30\u80de\u304c\u30a2\u30ec\u30eb\u30b2\u30f3\u306b\u5bfe\u3057\u3066\u3069\u306e\u3088\u3046\u306b\u53cd\u5fdc\u3059\u308b\u304b\u3092\u8abf\u6574\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001<strong>STAT6\u907a\u4f1d\u5b50<\/strong>\u306f\u3001IgE\u6297\u4f53\u306e\u7523\u751f\u3092\u8abf\u7bc0\u3059\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u7279\u5b9a\u306e\u98df\u7269\u306b\u5bfe\u3059\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u5f37\u3081\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u304c\u3082\u305f\u3089\u3059\u672a\u6765<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"574\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/31502889_m-1024x574.jpg\" alt=\"\u7814\u7a76\u5ba4\" class=\"wp-image-2772\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31502889_m-1024x574.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31502889_m-300x168.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31502889_m-768x430.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31502889_m-1536x861.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31502889_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8fd1\u5e74\u306e\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306e\u7406\u89e3\u304c\u98db\u8e8d\u7684\u306b\u6df1\u307e\u308a\u307e\u3057\u305f\u3002\u4ee5\u4e0b\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u7814\u7a76\u304c\u3069\u306e\u3088\u3046\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u3084\u4e88\u9632\u306b\u5fdc\u7528\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u3092\u63a2\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306b\u3088\u308b\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<p>CRISPR-Cas9\u306a\u3069\u306e\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u6cbb\u7642\u306b\u9769\u547d\u3092\u3082\u305f\u3089\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u6280\u8853\u3092\u4f7f\u7528\u3057\u3066\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u5909\u7570\u3092\u4fee\u6b63\u3059\u308b\u3053\u3068\u3067\u3001\u6839\u672c\u7684\u306a\u6cbb\u7642\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001<strong>IL4R\u907a\u4f1d\u5b50<\/strong>\u3084<strong>STAT6\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u3092\u6a19\u7684\u3068\u3059\u308b\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u6280\u8853\u306f\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306e\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.nature.com\"> Nature &#8211; \u907a\u4f1d\u5b50\u7de8\u96c6\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u500b\u5225\u5316\u533b\u7642\u306e\u9032\u5c55<\/strong><\/h3>\n\n\n\n<p>\u500b\u5225\u5316\u533b\u7642\u306f\u3001\u60a3\u8005\u3054\u3068\u306e\u907a\u4f1d\u7684\u7279\u5fb4\u306b\u57fa\u3065\u3044\u3066\u6cbb\u7642\u3092\u6700\u9069\u5316\u3059\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u3059\u3002\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u3063\u3066\u7279\u5b9a\u3055\u308c\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u30ea\u30b9\u30af\u3092\u57fa\u306b\u3001\u4e88\u9632\u7b56\u3084\u6cbb\u7642\u6cd5\u3092\u500b\u3005\u306b\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u60a3\u8005\u306b\u5bfe\u3057\u3066\u306f\u3001\u514d\u75ab\u7642\u6cd5\u306e\u52b9\u679c\u3092\u6700\u5927\u5316\u3059\u308b\u305f\u3081\u306e\u6cbb\u7642\u8a08\u753b\u304c\u7acb\u3066\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u6cbb\u7642\u306e\u6210\u529f\u7387\u304c\u5411\u4e0a\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u3082\u8efd\u6e1b\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u74b0\u5883\u8981\u56e0\u3068\u306e\u3055\u3089\u306a\u308b\u7814\u7a76\u306e\u5fc5\u8981\u6027<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u91cd\u8981\u306a\u8981\u56e0\u3067\u3042\u308b\u3053\u3068\u306f\u9593\u9055\u3044\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u74b0\u5883\u8981\u56e0\u3082\u7121\u8996\u3067\u304d\u307e\u305b\u3093\u3002\u7279\u306b\u4ee5\u4e0b\u306e\u5206\u91ce\u3067\u306e\u7814\u7a76\u304c\u4eca\u5f8c\u306e\u8ab2\u984c\u3068\u3057\u3066\u6319\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u98df\u751f\u6d3b\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7<\/strong><\/h3>\n\n\n\n<p>\u73fe\u4ee3\u306e\u98df\u751f\u6d3b\u306e\u5909\u5316\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7\u306e\u5897\u52a0\u3068\u5bc6\u63a5\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u52a0\u5de5\u98df\u54c1\u3084\u4fdd\u5b58\u6599\u306e\u591a\u3044\u98df\u54c1\u304c\u8178\u5185\u7d30\u83cc\u53e2\u3092\u5909\u5316\u3055\u305b\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u5730\u4e2d\u6d77\u98df\u306e\u3088\u3046\u306a\u30d0\u30e9\u30f3\u30b9\u306e\u53d6\u308c\u305f\u98df\u4e8b\u304c\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u3092\u6301\u3064\u4eba\u3005\u3067\u3082\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\"> \u5730\u4e2d\u6d77\u98df\u3068\u30a2\u30ec\u30eb\u30ae\u30fc &#8211; PubMed<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u74b0\u5883\u6c5a\u67d3\u3068\u30a2\u30ec\u30eb\u30ae\u30fc<\/strong><\/h3>\n\n\n\n<p>\u90fd\u5e02\u90e8\u306e\u7a7a\u6c17\u6c5a\u67d3\u3084\u5316\u5b66\u7269\u8cea\u306e\u5897\u52a0\u304c\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u3092\u60aa\u5316\u3055\u305b\u308b\u8981\u56e0\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u74b0\u5883\u8981\u56e0\u306f\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u3092\u6301\u3064\u4eba\u3005\u306b\u7279\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>PM2.5<\/strong>\u306e\u3088\u3046\u306a\u5fae\u5c0f\u7c92\u5b50\u72b6\u7269\u8cea\u304c\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u3092\u904e\u5270\u306b\u523a\u6fc0\u3057\u3001\u5598\u606f\u3084\u82b1\u7c89\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u4e88\u9632\u3068\u7ba1\u7406\u306e\u305f\u3081\u306e\u5177\u4f53\u7684\u306a\u5bfe\u7b56<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/30164890_m-1024x683.jpg\" alt=\"\u8d64\u3061\u3083\u3093\u3000\u6ce3\u304f\" class=\"wp-image-1502\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30164890_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30164890_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30164890_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30164890_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30164890_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306b\u57fa\u3065\u304f\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u3068\u7ba1\u7406\u306e\u305f\u3081\u306e\u65b0\u3057\u3044\u53ef\u80fd\u6027\u3092\u958b\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u306e\u6d3b\u7528<\/strong><\/h3>\n\n\n\n<p>\u8178\u5185\u7d30\u83cc\u53e2\u3092\u5065\u5eb7\u7684\u306b\u4fdd\u3064\u3053\u3068\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u305f\u3081\u306e\u6709\u52b9\u306a\u65b9\u6cd5\u306e\u4e00\u3064\u3067\u3059\u3002\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3092\u542b\u3080\u98df\u54c1\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u4eba\u3005\u306b\u5bfe\u3057\u3066\u3082\u6709\u76ca\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u74b0\u5883\u8abf\u6574<\/strong><\/h3>\n\n\n\n<p>\u5bb6\u5ead\u5185\u306e\u7a7a\u6c17\u8cea\u306e\u5411\u4e0a\u3084\u30a2\u30ec\u30eb\u30b2\u30f3\u306e\u6392\u9664\u3082\u91cd\u8981\u3067\u3059\u3002\u7279\u306b\u3001\u30c0\u30cb\u3001\u30ab\u30d3\u3001\u30da\u30c3\u30c8\u306e\u6bdb\u306a\u3069\u306e\u30a2\u30ec\u30eb\u30b2\u30f3\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u7de9\u548c\u3059\u308b\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.allergy-environment.jp\"> \u74b0\u5883\u30a2\u30ec\u30eb\u30ae\u30fc\u7814\u7a76\u30bb\u30f3\u30bf\u30fc<\/a><\/p>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u5909\u7570\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306e\u5177\u4f53\u4f8b<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u5909\u7570\u304c\u95a2\u4e0e\u3059\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306b\u306f\u3001\u591a\u304f\u306e\u5177\u4f53\u4f8b\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u4ee3\u8868\u7684\u306a\u75be\u60a3\u3092\u3044\u304f\u3064\u304b\u6319\u3052\u3001\u305d\u308c\u305e\u308c\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u3092\u8a73\u3057\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306f\u3001\u5b50\u4f9b\u304b\u3089\u5927\u4eba\u307e\u3067\u5e45\u5e83\u3044\u5e74\u4ee3\u306b\u898b\u3089\u308c\u308b\u6162\u6027\u7684\u306a\u76ae\u819a\u75be\u60a3\u3067\u3059\u3002\u3053\u306e\u75be\u60a3\u306b\u306f\u3001<strong>FLG\u907a\u4f1d\u5b50<\/strong>\u4ee5\u5916\u306b\u3082\u591a\u304f\u306e\u907a\u4f1d\u5b50\u304c\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001<strong>SPINK5\u907a\u4f1d\u5b50<\/strong>\u306f\u76ae\u819a\u30d0\u30ea\u30a2\u3092\u4fdd\u3064\u305f\u3081\u306b\u91cd\u8981\u306a\u9175\u7d20\u3092\u30b3\u30fc\u30c9\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u76ae\u819a\u306e\u4fdd\u8b77\u80fd\u529b\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3084\u5598\u606f\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001<strong>IL13\u907a\u4f1d\u5b50<\/strong>\u306f\u708e\u75c7\u53cd\u5fdc\u306b\u95a2\u4e0e\u3057\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u304c\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u306e\u60aa\u5316\u306b\u5bc4\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.atopy-foundation.org\"> \u30a2\u30c8\u30d4\u30fc\u7814\u7a76\u8ca1\u56e3<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u5598\u606f\u3068\u907a\u4f1d\u7684\u5f71\u97ff<\/strong><\/h3>\n\n\n\n<p>\u5598\u606f\u306f\u3001\u6c17\u9053\u306e\u708e\u75c7\u3068\u72ed\u7a84\u3092\u7279\u5fb4\u3068\u3059\u308b\u75be\u60a3\u3067\u3001\u907a\u4f1d\u7684\u8981\u56e0\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u5598\u606f\u306b\u95a2\u9023\u3059\u308b\u4e3b\u8981\u306a\u907a\u4f1d\u5b50\u306e\u4e00\u3064\u304c\u3001<strong>ADAM33\u907a\u4f1d\u5b50<\/strong>\u3067\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306f\u6c17\u9053\u306e\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\uff08\u69cb\u9020\u5909\u5316\uff09\u306b\u95a2\u4e0e\u3057\u3001\u7279\u5b9a\u306e\u5909\u7570\u304c\u3042\u308b\u3068\u6c17\u9053\u306e\u904e\u654f\u6027\u304c\u9ad8\u307e\u308a\u3001\u5598\u606f\u767a\u75c7\u30ea\u30b9\u30af\u304c\u5897\u52a0\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001<strong>ORMDL3\u907a\u4f1d\u5b50<\/strong>\u3082\u5598\u606f\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u591a\u578b\u306f\u3001\u6c17\u9053\u306e\u708e\u75c7\u3092\u8abf\u7bc0\u3059\u308b\u91cd\u8981\u306a\u56e0\u5b50\u3067\u3042\u308a\u3001\u6b27\u7c73\u3084\u30a2\u30b8\u30a2\u3092\u542b\u3080\u3055\u307e\u3056\u307e\u306a\u96c6\u56e3\u3067\u5598\u606f\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.asthma-genetics.jp\"> \u56fd\u7acb\u5598\u606f\u5b66\u4f1a &#8211; \u907a\u4f1d\u5b50\u7814\u7a76<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u3068\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u98df\u7269\u30a2\u30ec\u30eb\u30ae\u30fc\u306f\u3001\u7279\u5b9a\u306e\u98df\u7269\u3092\u6442\u53d6\u3057\u305f\u969b\u306b\u904e\u5270\u306a\u514d\u75ab\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3059\u75be\u60a3\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u30a2\u30ec\u30eb\u30ae\u30fc\u306f\u3001<strong>CD14\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u3068\u95a2\u9023\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306f\u3001\u514d\u75ab\u7d30\u80de\u304c\u30a2\u30ec\u30eb\u30b2\u30f3\u306b\u5bfe\u3057\u3066\u3069\u306e\u3088\u3046\u306b\u53cd\u5fdc\u3059\u308b\u304b\u3092\u8abf\u6574\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001<strong>STAT6\u907a\u4f1d\u5b50<\/strong>\u306f\u3001IgE\u6297\u4f53\u306e\u7523\u751f\u3092\u8abf\u7bc0\u3059\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u7279\u5b9a\u306e\u98df\u7269\u306b\u5bfe\u3059\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u5f37\u3081\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u304c\u3082\u305f\u3089\u3059\u672a\u6765<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/31766477_m-1024x683.jpg\" alt=\"\u8a66\u9a13\u7ba1\u3000\u7814\u7a76\" class=\"wp-image-2879\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31766477_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31766477_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31766477_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31766477_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/31766477_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u8fd1\u5e74\u306e\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306e\u7406\u89e3\u304c\u98db\u8e8d\u7684\u306b\u6df1\u307e\u308a\u307e\u3057\u305f\u3002\u4ee5\u4e0b\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u7814\u7a76\u304c\u3069\u306e\u3088\u3046\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u3084\u4e88\u9632\u306b\u5fdc\u7528\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u3092\u63a2\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306b\u3088\u308b\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<p>CRISPR-Cas9\u306a\u3069\u306e\u907a\u4f1d\u5b50\u7de8\u96c6\u6280\u8853\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u6cbb\u7642\u306b\u9769\u547d\u3092\u3082\u305f\u3089\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u6280\u8853\u3092\u4f7f\u7528\u3057\u3066\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u5909\u7570\u3092\u4fee\u6b63\u3059\u308b\u3053\u3068\u3067\u3001\u6839\u672c\u7684\u306a\u6cbb\u7642\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001<strong>IL4R\u907a\u4f1d\u5b50<\/strong>\u3084<strong>STAT6\u907a\u4f1d\u5b50<\/strong>\u306e\u5909\u7570\u3092\u6a19\u7684\u3068\u3059\u308b\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u6280\u8853\u306f\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306e\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.nature.com\"> Nature &#8211; \u907a\u4f1d\u5b50\u7de8\u96c6\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u500b\u5225\u5316\u533b\u7642\u306e\u9032\u5c55<\/strong><\/h3>\n\n\n\n<p>\u500b\u5225\u5316\u533b\u7642\u306f\u3001\u60a3\u8005\u3054\u3068\u306e\u907a\u4f1d\u7684\u7279\u5fb4\u306b\u57fa\u3065\u3044\u3066\u6cbb\u7642\u3092\u6700\u9069\u5316\u3059\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u3059\u3002\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u3063\u3066\u7279\u5b9a\u3055\u308c\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u30ea\u30b9\u30af\u3092\u57fa\u306b\u3001\u4e88\u9632\u7b56\u3084\u6cbb\u7642\u6cd5\u3092\u500b\u3005\u306b\u30ab\u30b9\u30bf\u30de\u30a4\u30ba\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u60a3\u8005\u306b\u5bfe\u3057\u3066\u306f\u3001\u514d\u75ab\u7642\u6cd5\u306e\u52b9\u679c\u3092\u6700\u5927\u5316\u3059\u308b\u305f\u3081\u306e\u6cbb\u7642\u8a08\u753b\u304c\u7acb\u3066\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u6cbb\u7642\u306e\u6210\u529f\u7387\u304c\u5411\u4e0a\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u3082\u8efd\u6e1b\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u74b0\u5883\u8981\u56e0\u3068\u306e\u3055\u3089\u306a\u308b\u7814\u7a76\u306e\u5fc5\u8981\u6027<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u91cd\u8981\u306a\u8981\u56e0\u3067\u3042\u308b\u3053\u3068\u306f\u9593\u9055\u3044\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u74b0\u5883\u8981\u56e0\u3082\u7121\u8996\u3067\u304d\u307e\u305b\u3093\u3002\u7279\u306b\u4ee5\u4e0b\u306e\u5206\u91ce\u3067\u306e\u7814\u7a76\u304c\u4eca\u5f8c\u306e\u8ab2\u984c\u3068\u3057\u3066\u6319\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u98df\u751f\u6d3b\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7<\/strong><\/h3>\n\n\n\n<p>\u73fe\u4ee3\u306e\u98df\u751f\u6d3b\u306e\u5909\u5316\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7\u306e\u5897\u52a0\u3068\u5bc6\u63a5\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u52a0\u5de5\u98df\u54c1\u3084\u4fdd\u5b58\u6599\u306e\u591a\u3044\u98df\u54c1\u304c\u8178\u5185\u7d30\u83cc\u53e2\u3092\u5909\u5316\u3055\u305b\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u5730\u4e2d\u6d77\u98df\u306e\u3088\u3046\u306a\u30d0\u30e9\u30f3\u30b9\u306e\u53d6\u308c\u305f\u98df\u4e8b\u304c\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u3092\u6301\u3064\u4eba\u3005\u3067\u3082\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\"> \u5730\u4e2d\u6d77\u98df\u3068\u30a2\u30ec\u30eb\u30ae\u30fc &#8211; PubMed<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u74b0\u5883\u6c5a\u67d3\u3068\u30a2\u30ec\u30eb\u30ae\u30fc<\/strong><\/h3>\n\n\n\n<p>\u90fd\u5e02\u90e8\u306e\u7a7a\u6c17\u6c5a\u67d3\u3084\u5316\u5b66\u7269\u8cea\u306e\u5897\u52a0\u304c\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u3092\u60aa\u5316\u3055\u305b\u308b\u8981\u56e0\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u74b0\u5883\u8981\u56e0\u306f\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u3092\u6301\u3064\u4eba\u3005\u306b\u7279\u306b\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001<strong>PM2.5<\/strong>\u306e\u3088\u3046\u306a\u5fae\u5c0f\u7c92\u5b50\u72b6\u7269\u8cea\u304c\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u3092\u904e\u5270\u306b\u523a\u6fc0\u3057\u3001\u5598\u606f\u3084\u82b1\u7c89\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u4e88\u9632\u3068\u7ba1\u7406\u306e\u305f\u3081\u306e\u5177\u4f53\u7684\u306a\u5bfe\u7b56<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/24486081_m-1024x683.jpg\" alt=\"\u6383\u9664\u3059\u308b\u3000\u7537\u5973\" class=\"wp-image-2886\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24486081_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24486081_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24486081_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24486081_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/24486081_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306b\u57fa\u3065\u304f\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u3068\u7ba1\u7406\u306e\u305f\u3081\u306e\u65b0\u3057\u3044\u53ef\u80fd\u6027\u3092\u958b\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u306e\u6d3b\u7528<\/strong><\/h3>\n\n\n\n<p>\u8178\u5185\u7d30\u83cc\u53e2\u3092\u5065\u5eb7\u7684\u306b\u4fdd\u3064\u3053\u3068\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u305f\u3081\u306e\u6709\u52b9\u306a\u65b9\u6cd5\u306e\u4e00\u3064\u3067\u3059\u3002\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3092\u542b\u3080\u98df\u54c1\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u578b\u3092\u6301\u3064\u4eba\u3005\u306b\u5bfe\u3057\u3066\u3082\u6709\u76ca\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u74b0\u5883\u8abf\u6574<\/strong><\/h3>\n\n\n\n<p>\u5bb6\u5ead\u5185\u306e\u7a7a\u6c17\u8cea\u306e\u5411\u4e0a\u3084\u30a2\u30ec\u30eb\u30b2\u30f3\u306e\u6392\u9664\u3082\u91cd\u8981\u3067\u3059\u3002\u7279\u306b\u3001\u30c0\u30cb\u3001\u30ab\u30d3\u3001\u30da\u30c3\u30c8\u306e\u6bdb\u306a\u3069\u306e\u30a2\u30ec\u30eb\u30b2\u30f3\u3092\u6e1b\u3089\u3059\u3053\u3068\u304c\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u7de9\u548c\u3059\u308b\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.allergy-environment.jp\"> \u74b0\u5883\u30a2\u30ec\u30eb\u30ae\u30fc\u7814\u7a76\u30bb\u30f3\u30bf\u30fc<\/a><\/p>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u5bfe\u3059\u308b\u6700\u65b0\u6cbb\u7642\u6cd5<\/strong><\/h2>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u6cd5\u306f\u9032\u5316\u3092\u7d9a\u3051\u3066\u304a\u308a\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u6210\u679c\u3092\u57fa\u306b\u3057\u305f\u65b0\u3057\u3044\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u6cbb\u7642\u6cd5\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u6839\u672c\u539f\u56e0\u306b\u30a2\u30d7\u30ed\u30fc\u30c1\u3057\u3001\u75c7\u72b6\u306e\u8efd\u6e1b\u3084\u5b8c\u5168\u306a\u514b\u670d\u3092\u76ee\u6307\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u7642\u6cd5<\/strong><\/h3>\n\n\n\n<p>\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u7642\u6cd5\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u75be\u60a3\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u6700\u65b0\u306e\u624b\u6cd5\u306e\u4e00\u3064\u3067\u3059\u3002\u3053\u306e\u6cbb\u7642\u6cd5\u3067\u306f\u3001\u514d\u75ab\u7cfb\u304c\u904e\u5270\u53cd\u5fdc\u3092\u8d77\u3053\u3059\u539f\u56e0\u3068\u306a\u308b\u7279\u5b9a\u306e\u5206\u5b50\u3092\u6a19\u7684\u3068\u3059\u308b\u6297\u4f53\u3092\u4f7f\u7528\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>**\u30c7\u30e5\u30d4\u30eb\u30de\u30d6\uff08Dupilumab\uff09**\u306f\u305d\u306e\u4ee3\u8868\u4f8b\u3067\u3042\u308a\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3084\u5598\u606f\u306e\u6cbb\u7642\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u85ac\u5264\u306f\u3001IL-4\u304a\u3088\u3073IL-13\u3068\u3044\u3063\u305f\u514d\u75ab\u30b7\u30b0\u30ca\u30eb\u5206\u5b50\u306e\u50cd\u304d\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u3001\u708e\u75c7\u3092\u6291\u5236\u3057\u307e\u3059\u3002\u7279\u306b\u3001\u3053\u308c\u3089\u306e\u514d\u75ab\u30b7\u30b0\u30ca\u30eb\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u60a3\u8005\u306b\u5bfe\u3057\u3066\u9ad8\u3044\u52b9\u679c\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\"> \u30c7\u30e5\u30d4\u30eb\u30de\u30d6\u306b\u95a2\u3059\u308b\u7814\u7a76 &#8211; PubMed<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. RNA\u5e72\u6e09\uff08RNAi\uff09\u306b\u3088\u308b\u6cbb\u7642<\/strong><\/h3>\n\n\n\n<p>RNA\u5e72\u6e09\uff08RNAi\uff09\u6280\u8853\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u8efd\u6e1b\u3059\u308b\u65b9\u6cd5\u3067\u3059\u3002\u3053\u306e\u6280\u8853\u306f\u3001\u907a\u4f1d\u5b50\u5909\u7570\u304c\u76f4\u63a5\u7684\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u5f15\u304d\u8d77\u3053\u3059\u5834\u5408\u306b\u7279\u306b\u6709\u52b9\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001IgE\u6297\u4f53\u306e\u7523\u751f\u3092\u6291\u5236\u3059\u308bRNAi\u6cbb\u7642\u6cd5\u306f\u3001\u91cd\u5ea6\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u6301\u3064\u60a3\u8005\u306b\u5bfe\u3057\u3066\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6cbb\u7642\u6cd5\u306f\u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u30a2\u30ec\u30eb\u30ae\u30fc\u3084\u91cd\u75c7\u306e\u82b1\u7c89\u75c7\u306a\u3069\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u73fe\u5728\u81e8\u5e8a\u8a66\u9a13\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u7642\u6cd5<\/strong><\/h3>\n\n\n\n<p>\u8178\u5185\u7d30\u83cc\u53e2\uff08\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\uff09\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u308b\u3053\u3068\u3067\u3001\u514d\u75ab\u7cfb\u306e\u904e\u5270\u53cd\u5fdc\u3092\u6291\u5236\u3059\u308b\u6cbb\u7642\u6cd5\u3082\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u5b9a\u306e\u8178\u5185\u7d30\u83cc\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u8efd\u6e1b\u3059\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304a\u308a\u3001\u3053\u308c\u3092\u5229\u7528\u3057\u305f\u6cbb\u7642\u304c\u9032\u884c\u4e2d\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001<strong>Faecalibacterium prausnitzii<\/strong>\u3068\u3044\u3046\u7d30\u83cc\u306f\u3001\u8178\u5185\u306e\u708e\u75c7\u3092\u6291\u5236\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u7de9\u548c\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u7d30\u83cc\u3092\u542b\u3080\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3084\u3001\u8178\u5185\u7d30\u83cc\u79fb\u690d\uff08FMT\uff09\u304c\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.gutmicrobiota.org\"> \u8178\u5185\u7d30\u83cc\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u7814\u7a76 &#8211; Gut Microbiota<\/a><\/p>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u5bfe\u3059\u308b\u4e88\u9632\u306e\u53ef\u80fd\u6027<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/30985389_m-1024x683.jpg\" alt=\"\u76f8\u8ac7\u3000\u533b\u8005\u3000\u5973\u6027\" class=\"wp-image-1648\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30985389_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30985389_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30985389_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30985389_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/30985389_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u3092\u4e88\u9632\u3059\u308b\u305f\u3081\u306e\u53d6\u308a\u7d44\u307f\u306f\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u3084\u74b0\u5883\u8abf\u6574\u306e\u6210\u679c\u3092\u57fa\u306b\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u3053\u3067\u306f\u3001\u6700\u65b0\u306e\u4e88\u9632\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u65e9\u671f\u4ecb\u5165\u3068\u514d\u75ab\u8010\u6027\u306e\u4fc3\u9032<\/strong><\/h3>\n\n\n\n<p>\u8d64\u3061\u3083\u3093\u306e\u65e9\u3044\u6bb5\u968e\u3067\u5c11\u91cf\u306e\u30a2\u30ec\u30eb\u30b2\u30f3\u306b\u89e6\u308c\u308b\u3053\u3068\u3067\u3001\u514d\u75ab\u8010\u6027\u3092\u80b2\u3066\u308b\u53d6\u308a\u7d44\u307f\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u4e88\u9632\u306b\u306f\u3001\u751f\u5f8c6\u304b\u6708\u304b\u308912\u304b\u6708\u306e\u9593\u306b\u30d4\u30fc\u30ca\u30c3\u30c4\u88fd\u54c1\u3092\u5c11\u91cf\u6442\u53d6\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u767a\u75c7\u7387\u3092\u5927\u5e45\u306b\u6e1b\u5c11\u3055\u305b\u308b\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u725b\u4e73\u3084\u5375\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u4e88\u9632\u306e\u305f\u3081\u306b\u3082\u3001\u9069\u5207\u306a\u30bf\u30a4\u30df\u30f3\u30b0\u3067\u306e\u98df\u4e8b\u5c0e\u5165\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.leapstudy.org\"> LEAP\u7814\u7a76 &#8211; \u30d4\u30fc\u30ca\u30c3\u30c4\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u4e88\u9632<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u74b0\u5883\u8981\u56e0\u306e\u7ba1\u7406<\/strong><\/h3>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u4e88\u9632\u306b\u306f\u3001\u751f\u6d3b\u74b0\u5883\u306e\u6700\u9069\u5316\u304c\u91cd\u8981\u3067\u3059\u3002\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5177\u4f53\u7684\u306a\u53d6\u308a\u7d44\u307f\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u7a7a\u6c17\u6e05\u6d44\u6a5f\u3092\u4f7f\u7528\u3057\u3066\u3001\u82b1\u7c89\u3084\u30cf\u30a6\u30b9\u30c0\u30b9\u30c8\u3092\u6e1b\u5c11\u3055\u305b\u308b\u3002<\/li>\n\n\n\n<li>\u5ba4\u5185\u306e\u6e7f\u5ea6\u309240\uff5e60%\u306b\u4fdd\u3061\u3001\u30ab\u30d3\u3084\u30c0\u30cb\u306e\u7e41\u6b96\u3092\u9632\u3050\u3002<\/li>\n\n\n\n<li>\u30da\u30c3\u30c8\u3092\u98fc\u3046\u5834\u5408\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306e\u4eba\u306b\u306f\u4f4e\u30a2\u30ec\u30eb\u30b2\u30f3\u54c1\u7a2e\u3092\u9078\u3076\u3002<\/li>\n<\/ul>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u4e16\u754c\u7684\u306a\u30a2\u30ec\u30eb\u30ae\u30fc\u5bfe\u7b56\u306e\u52d5\u5411<\/strong><\/h2>\n\n\n\n<p>\u4e16\u754c\u7684\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u60a3\u8005\u306f\u5897\u52a0\u50be\u5411\u306b\u3042\u308a\u3001\u7279\u306b\u90fd\u5e02\u90e8\u3067\u306e\u5897\u52a0\u304c\u9855\u8457\u3067\u3059\u3002\u3053\u306e\u80cc\u666f\u306b\u306f\u3001\u7a7a\u6c17\u6c5a\u67d3\u3084\u98df\u54c1\u306e\u52a0\u5de5\u6280\u8853\u306e\u5909\u5316\u304c\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306b\u3001\u5404\u56fd\u306e\u5bfe\u7b56\u4f8b\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u6b27\u7c73\u8af8\u56fd\u306e\u53d6\u308a\u7d44\u307f<\/strong><\/h3>\n\n\n\n<p>\u6b27\u7c73\u3067\u306f\u3001\u5b66\u6821\u3084\u516c\u5171\u65bd\u8a2d\u306b\u304a\u3051\u308b\u30a2\u30ec\u30eb\u30ae\u30fc\u5bfe\u5fdc\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u30a2\u30e1\u30ea\u30ab\u3067\u306f\u98df\u54c1\u30a2\u30ec\u30eb\u30ae\u30fc\u3092\u6301\u3064\u5b50\u3069\u3082\u306e\u305f\u3081\u306b\u300c\u30ca\u30c3\u30c4\u30d5\u30ea\u30fc\u30be\u30fc\u30f3\u300d\u3092\u8a2d\u7f6e\u3059\u308b\u5b66\u6821\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30a4\u30ae\u30ea\u30b9\u3067\u306f\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u8a3a\u65ad\u3068\u6cbb\u7642\u306e\u5c02\u9580\u30af\u30ea\u30cb\u30c3\u30af\u304c\u591a\u304f\u958b\u8a2d\u3055\u308c\u3001\u907a\u4f1d\u5b50\u8a3a\u65ad\u3092\u57fa\u306b\u3057\u305f\u500b\u5225\u5316\u6cbb\u7642\u304c\u63d0\u4f9b\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u65e5\u672c\u306e\u53d6\u308a\u7d44\u307f<\/strong><\/h3>\n\n\n\n<p>\u65e5\u672c\u3067\u306f\u3001\u539a\u751f\u52b4\u50cd\u7701\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u306b\u95a2\u3059\u308b\u56fd\u306e\u57fa\u672c\u6307\u91dd\u3092\u7b56\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002\u98df\u54c1\u30a2\u30ec\u30eb\u30ae\u30fc\u3084\u5598\u606f\u306b\u95a2\u3059\u308b\u5168\u56fd\u7684\u306a\u8abf\u67fb\u304c\u5b9a\u671f\u7684\u306b\u884c\u308f\u308c\u3066\u304a\u308a\u3001\u7814\u7a76\u30c7\u30fc\u30bf\u3092\u6d3b\u7528\u3057\u305f\u653f\u7b56\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u5c0f\u5150\u5411\u3051\u306e\u30a2\u30ec\u30eb\u30ae\u30fc\u6559\u80b2\u3084\u3001\u75c5\u9662\u3068\u5b66\u6821\u304c\u9023\u643a\u3057\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u5bfe\u5fdc\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u958b\u767a\u3082\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>: \u539a\u751f\u52b4\u50cd\u7701 &#8211; \u30a2\u30ec\u30eb\u30ae\u30fc\u75be\u60a3\u5bfe\u7b56<\/p>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30a2\u30ec\u30eb\u30ae\u30fc\u514b\u670d\u306b\u5411\u3051\u305f\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u6539\u5584<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/gene\/wp-content\/uploads\/2024\/12\/4629627_m-1024x683.jpg\" alt=\"\u6804\u990a\u30d0\u30e9\u30f3\u30b9\" class=\"wp-image-2893\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4629627_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4629627_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4629627_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4629627_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/gene\/wp-content\/uploads\/2024\/12\/4629627_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306e\u5f71\u97ff\u3092\u53d7\u3051\u305f\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u3067\u3042\u3063\u3066\u3082\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u6539\u5584\u306b\u3088\u3063\u3066\u75c7\u72b6\u3092\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u4ee5\u4e0b\u306f\u3001\u65e5\u5e38\u751f\u6d3b\u3067\u5b9f\u8df5\u3067\u304d\u308b\u5177\u4f53\u7684\u306a\u6539\u5584\u7b56\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>1. \u6804\u990a\u30d0\u30e9\u30f3\u30b9\u306e\u6539\u5584<\/strong><\/h3>\n\n\n\n<p>\u98df\u751f\u6d3b\u306f\u514d\u75ab\u7cfb\u306e\u5065\u5eb7\u306b\u76f4\u7d50\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u6297\u708e\u75c7\u4f5c\u7528\u3092\u6301\u3064\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u3092\u542b\u3080\u98df\u54c1\uff08\u9b5a\u3001\u30ca\u30c3\u30c4\u985e\uff09\u3084\u3001\u6297\u9178\u5316\u7269\u8cea\u3092\u591a\u304f\u542b\u3080\u30d5\u30eb\u30fc\u30c4\u3084\u91ce\u83dc\u3092\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3092\u542b\u3080\u98df\u54c1\uff08\u30e8\u30fc\u30b0\u30eb\u30c8\u3084\u5473\u564c\uff09\u3082\u8178\u5185\u74b0\u5883\u3092\u6574\u3048\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u8178\u5185\u74b0\u5883\u304c\u5065\u5eb7\u3067\u3042\u308c\u3070\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u304c\u7de9\u548c\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>2. \u30b9\u30c8\u30ec\u30b9\u7ba1\u7406<\/strong><\/h3>\n\n\n\n<p>\u30b9\u30c8\u30ec\u30b9\u306f\u514d\u75ab\u7cfb\u3092\u5f31\u4f53\u5316\u3055\u305b\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u60aa\u5316\u3055\u305b\u308b\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002\u7791\u60f3\u3084\u30e8\u30ac\u3001\u9069\u5ea6\u306a\u904b\u52d5\u306a\u3069\u306e\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u65b9\u6cd5\u3092\u53d6\u308a\u5165\u308c\u308b\u3053\u3068\u3067\u3001\u4f53\u5168\u4f53\u306e\u514d\u75ab\u30d0\u30e9\u30f3\u30b9\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>3. \u9069\u5207\u306a\u7761\u7720<\/strong><\/h3>\n\n\n\n<p>\u5341\u5206\u306a\u7761\u7720\u306f\u3001\u514d\u75ab\u7cfb\u306e\u6b63\u5e38\u306a\u6a5f\u80fd\u3092\u4fdd\u3064\u305f\u3081\u306b\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u7761\u7720\u4e0d\u8db3\u306f\u708e\u75c7\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3057\u3084\u3059\u304f\u3057\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u75c7\u72b6\u3092\u60aa\u5316\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u6bce\u66697\uff5e8\u6642\u9593\u306e\u826f\u8cea\u306a\u7761\u7720\u3092\u78ba\u4fdd\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u30a8\u30d3\u30c7\u30f3\u30b9<\/strong>:<a href=\"https:\/\/www.sleepfoundation.org\"> \u7761\u7720\u3068\u514d\u75ab\u7cfb\u306e\u95a2\u4fc2 &#8211; Sleep Foundation<\/a><\/p>\n\n\n\n<p><span id=\"docs-internal-guid-66c22874-7fff-025c-da1f-e558a702f260\"><span style=\"font-size: 11pt; font-family: Arial, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; font-variant-position: normal; font-variant-emoji: normal; vertical-align: baseline;\"><div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div><\/span><\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u307e\u3068\u3081<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u306f\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u306e\u5f62\u6210\u306b\u5927\u304d\u304f\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001FLG\u3084IL4R\u306a\u3069\u306e\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u75be\u60a3\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u98df\u751f\u6d3b\u3084\u30b9\u30c8\u30ec\u30b9\u7ba1\u7406\u3001\u74b0\u5883\u8981\u56e0\u306e\u8abf\u6574\u3068\u3044\u3063\u305f\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u6539\u5584\u306b\u3088\u308a\u3001\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u307e\u305f\u3001\u907a\u4f1d\u5b50\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001RNA\u5e72\u6e09\u3084\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u7642\u6cd5\u306a\u3069\u3001\u500b\u5225\u5316\u533b\u7642\u304c\u767a\u5c55\u3057\u3066\u3044\u307e\u3059\u3002\u4eca\u5f8c\u3001\u907a\u4f1d\u5b50\u3068\u74b0\u5883\u8981\u56e0\u3092\u7d71\u5408\u3057\u305f\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u3068\u4e88\u9632\u306e\u65b0\u305f\u306a\u9053\u3092\u5207\u308a\u958b\u304f\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n <a href=\"https:\/\/www.generio.jp\/view\/category\/GC-CAR\" target=\"_blank\"><\/p>\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u672a\u6765\u3092\u77e5\u308b\u305f\u3081\u306e<span>\u6700\u65b0\u6280\u8853<\/span><\/p>\n<p class=\"btn\">\u3054\u8cfc\u5165\u306f\u3053\u3061\u3089<\/p>\n<\/p><\/div>\n<p> <\/a>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u907a\u4f1d\u5b50\u3068\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u95a2\u4fc2 \u30a2\u30ec\u30eb\u30ae\u30fc\u306f\u3001\u514d\u75ab\u7cfb\u304c\u7279\u5b9a\u306e\u7269\u8cea\u306b\u904e\u5270\u53cd\u5fdc\u3059\u308b\u3053\u3068\u3067\u5f15\u304d\u8d77\u3053\u3055\u308c\u307e\u3059\u3002\u907a\u4f1d\u7684\u8981\u56e0\u3068\u74b0\u5883\u7684\u8981\u56e0\u304c\u8907\u96d1\u306b\u7d61\u307f\u5408\u3044\u3001\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u767a\u75c7\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u3002\u7279\u306b\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u30a2\u30ec\u30eb\u30ae\u30fc\u4f53\u8cea\u3092\u4f5c\u308a\u51fa\u3059\u91cd\u8981\u306a [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":1350,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-983","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-technology"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/983","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/comments?post=983"}],"version-history":[{"count":3,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/983\/revisions"}],"predecessor-version":[{"id":2900,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/posts\/983\/revisions\/2900"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media\/1350"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/media?parent=983"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/categories?post=983"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/gene\/wp-json\/wp\/v2\/tags?post=983"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}