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https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/31352567_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u7d2b\u5916\u7dda\u306f\u5b63\u7bc0\u3092\u554f\u308f\u305a\u76ae\u819a\u7d30\u80de\u306e\u30bf\u30fc\u30f3\u30aa\u30fc\u30d0\u30fc\uff08\u518d\u751f\u30b5\u30a4\u30af\u30eb\uff09\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u79cb\u51ac\u306f\u6c17\u6e29\u306e\u4f4e\u4e0b\u306b\u3088\u308a\u8840\u884c\u304c\u6ede\u308a\u304c\u3061\u3067\u3001\u76ae\u819a\u306e\u4ee3\u8b1d\u6d3b\u52d5\u3082\u920d\u304f\u306a\u308b\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002\u305d\u3053\u306b\u7d2b\u5916\u7dda\u306b\u3088\u308b\u9178\u5316\u30c0\u30e1\u30fc\u30b8\u304c\u52a0\u308f\u308b\u3068\u3001\u7d30\u80de\u306e\u4fee\u5fa9\u304c\u8ffd\u3044\u3064\u304b\u305a\u3001\u8272\u7d20\u6c88\u7740\u3084\u4e7e\u71e5\u3001\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u62db\u304d\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u5bd2\u3055\u306b\u3088\u308b\u76ae\u8102\u30fb\u6c57\u306e\u5206\u6ccc\u91cf\u306e\u4f4e\u4e0b\u306f\u3001\u808c\u306e\u5929\u7136\u4fdd\u6e7f\u56e0\u5b50\uff08NMF\uff09\u3084\u76ae\u8102\u819c\u306e\u5f62\u6210\u3092\u59a8\u3052\u3001\u7d2b\u5916\u7dda\u304b\u3089\u306e\u9632\u5fa1\u80fd\u529b\u3092\u8457\u3057\u304f\u5f31\u3081\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u72b6\u614b\u3067\u306e\u7d2b\u5916\u7dda\u66dd\u9732\u306f\u3001\u30c0\u30e1\u30fc\u30b8\u304c\u300c\u84c4\u7a4d\u300d\u3055\u308c\u3084\u3059\u304f\u3001\u898b\u305f\u76ee\u4ee5\u4e0a\u306b\u6df1\u523b\u306a\u554f\u984c\u3092\u5f15\u304d\u8d77\u3053\u3059\u8981\u56e0\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u7d2b\u5916\u7dda\u304c\u5f15\u304d\u8d77\u3053\u3059\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u5909\u5316<\/strong><\/h2>\n\n\n\n<p>\u7d2b\u5916\u7dda\u306b\u3088\u308b\u5f71\u97ff\u306fDNA\u640d\u50b7\u306b\u3068\u3069\u307e\u3089\u305a\u3001\u8fd1\u5e74\u3067\u306f\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u306a\u5909\u5316\u306b\u3082\u95a2\u4e0e\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7d2b\u5916\u7dda\u306f\u3001DNA\u30e1\u30c1\u30eb\u5316\u30d1\u30bf\u30fc\u30f3\u306e\u5909\u5316\u3084\u30d2\u30b9\u30c8\u30f3\u4fee\u98fe\u3092\u8a98\u5c0e\u3057\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u306b\u9577\u671f\u7684\u306a\u5909\u5316\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f8b\u3048\u3070\u3001\u8001\u5316\u95a2\u9023\u907a\u4f1d\u5b50\u300cp16INK4a\u300d\u306e\u767a\u73fe\u4e0a\u6607\u306f\u3001\u7d2b\u5916\u7dda\u306b\u3088\u308b\u30d2\u30b9\u30c8\u30f3\u30a2\u30bb\u30c1\u30eb\u5316\u7570\u5e38\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u3053\u308c\u304c\u76ae\u819a\u306e\u518d\u751f\u529b\u4f4e\u4e0b\u3084\u52a0\u9f62\u6027\u5909\u5316\u306e\u4e00\u56e0\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u7d2b\u5916\u7dda\u5bfe\u7b56\u3092\u6020\u308b\u3053\u3068\u306f\u3001\u76ae\u819a\u3060\u3051\u3067\u306a\u304f\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u6052\u5e38\u6027\u3092\u3082\u63fa\u308b\u304c\u3059\u30ea\u30b9\u30af\u304c\u3042\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u53c2\u8003\u6587\u732e<\/strong>\uff1a<br>Poon, T. S., et al. (2005). Epigenetic regulation of p16INK4a in UV-exposed human skin: implications for carcinogenesis. <em>Journal of Investigative Dermatology<\/em>, 125(3), 483\u2013490.<br><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16185262\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/16185262\/<br><\/a><\/li>\n<\/ul>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9UV\u30b1\u30a2\u306e\u53ef\u80fd\u6027<\/strong><\/h2>\n\n\n\n<p>\u907a\u4f1d\u5b50\u30ec\u30d9\u30eb\u3067\u7d2b\u5916\u7dda\u30ea\u30b9\u30af\u3092\u5206\u6790\u3059\u308b\u53d6\u308a\u7d44\u307f\u306f\u3001\u500b\u5225\u5316\u533b\u7642\u3084\u30d1\u30fc\u30bd\u30ca\u30eb\u30b9\u30ad\u30f3\u30b1\u30a2\u306e\u5206\u91ce\u3067\u6025\u901f\u306b\u5e83\u304c\u3063\u3066\u3044\u307e\u3059\u3002DNA\u640d\u50b7\u4fee\u5fa9\u80fd\u529b\u3084\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u8010\u6027\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50\uff08\u4f8b\uff1aXPC\u3001SOD2\u3001GPX1\u306a\u3069\uff09\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u81ea\u5206\u81ea\u8eab\u306e\u7d2b\u5916\u7dda\u8010\u6027\u30ec\u30d9\u30eb\u3092\u5ba2\u89b3\u7684\u306b\u628a\u63e1\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u3001\u65e5\u672c\u4eba\u306b\u591a\u3044\u300cNQO1\uff08\u30ca\u30b8\u30aa\u30f3\uff09\u300d\u3068\u3044\u3046\u9175\u7d20\u306e\u907a\u4f1d\u5b50\u591a\u578b\u306f\u3001\u6297\u9178\u5316\u53cd\u5fdc\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u7d2b\u5916\u7dda\u306b\u3088\u308b\u9178\u5316\u30c0\u30e1\u30fc\u30b8\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u3092\u5de6\u53f3\u3059\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u60c5\u5831\u3092\u3082\u3068\u306b\u3001\u7d2b\u5916\u7dda\u5bfe\u7b56\u3092\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u5b9f\u7528\u4f8b\uff1a<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u7d2b\u5916\u7dda\u611f\u53d7\u6027\u304c\u9ad8\u3044\u30bf\u30a4\u30d7 \u2192 SPF50+\u30fbPA++++\u306e\u65e5\u713c\u3051\u6b62\u3081\u3092\u901a\u5e74\u4f7f\u7528<br><\/li>\n\n\n\n<li>\u6297\u9178\u5316\u529b\u304c\u5f31\u3044\u30bf\u30a4\u30d7 \u2192 \u30d3\u30bf\u30df\u30f3C\u3001E\u3001\u30a2\u30b9\u30bf\u30ad\u30b5\u30f3\u30c1\u30f3\u7b49\u306e\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u6d3b\u7528<br><\/li>\n\n\n\n<li>DNA\u4fee\u5fa9\u529b\u304c\u5f31\u3044\u30bf\u30a4\u30d7 \u2192 \u7d2b\u5916\u7dda\u66dd\u9732\u6642\u9593\u306e\u77ed\u7e2e\u3068\u5b9a\u671f\u7684\u306a\u76ae\u819a\u30c1\u30a7\u30c3\u30af\u306e\u5fb9\u5e95<br><\/li>\n<\/ul>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>UV\u30b1\u30a2\u3068\u3057\u3066\u306e\u7d4c\u53e3\u6442\u53d6\uff1a\u6297\u9178\u5316\u6804\u990a\u7d20\u3068\u690d\u7269\u7531\u6765\u6210\u5206<\/strong><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/31431800_m-1024x683.jpg\" alt=\"\n\u9752\u6c41\u3092\u98f2\u3080\u82e5\u3044\u5973\u6027\" class=\"wp-image-151\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/31431800_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/31431800_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/31431800_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/31431800_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/31431800_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u79cb\u51ac\u306e\u7d2b\u5916\u7dda\u5bfe\u7b56\u3068\u3057\u3066\u3001\u5916\u7528\u30b1\u30a2\u306b\u52a0\u3048\u3066\u300c\u5185\u5074\u304b\u3089\u306eUV\u30b1\u30a2\u300d\u304c\u6ce8\u76ee\u3092\u96c6\u3081\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u4ee5\u4e0b\u306e\u6804\u990a\u7d20\u3084\u690d\u7269\u6210\u5206\u306f\u3001\u7d2b\u5916\u7dda\u306b\u3088\u308b\u7d30\u80de\u30c0\u30e1\u30fc\u30b8\u3092\u8efd\u6e1b\u3059\u308b\u52b9\u679c\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30d3\u30bf\u30df\u30f3D\u306e\u4e8c\u9762\u6027<\/strong><\/h3>\n\n\n\n<p>\u51ac\u5b63\u306f\u65e5\u7167\u6642\u9593\u304c\u77ed\u304f\u306a\u308a\u3001\u4f53\u5185\u3067\u306e\u30d3\u30bf\u30df\u30f3D\u5408\u6210\u304c\u4f4e\u4e0b\u3059\u308b\u305f\u3081\u3001\u7d2b\u5916\u7dda\u3092\u5b8c\u5168\u306b\u906e\u65ad\u3059\u308b\u3053\u3068\u304c\u5065\u5eb7\u4e0a\u306e\u554f\u984c\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u30d3\u30bf\u30df\u30f3D\u306f\u65e5\u713c\u3051\u6b62\u3081\u3092\u5857\u5e03\u3057\u305f\u72b6\u614b\u3067\u3082\u5c4b\u5916\u306b15\u5206\u7a0b\u5ea6\u3044\u308c\u3070\u5341\u5206\u306b\u5408\u6210\u3055\u308c\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u904e\u5270\u306a\u65e5\u5149\u6d74\u3067\u306f\u306a\u304f\u3001\u9069\u5207\u306a\u6642\u9593\u30fb\u65b9\u6cd5\u3067\u306e\u6442\u53d6\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u985e<\/strong><\/h3>\n\n\n\n<p>\u7dd1\u8336\u30ab\u30c6\u30ad\u30f3\u3001\u30a2\u30f3\u30c8\u30b7\u30a2\u30cb\u30f3\u3001\u30ec\u30b9\u30d9\u30e9\u30c8\u30ed\u30fc\u30eb\u3068\u3044\u3063\u305f\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u306f\u3001\u6297\u9178\u5316\u30fb\u6297\u708e\u75c7\u4f5c\u7528\u3092\u901a\u3058\u3066\u7d2b\u5916\u7dda\u30c0\u30e1\u30fc\u30b8\u3092\u8efd\u6e1b\u3059\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u7279\u306bUV-A\u306b\u3088\u308b\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3078\u306e\u4fdd\u8b77\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u304a\u308a\u3001\u79cb\u51ac\u306e\u9593\u3082\u610f\u8b58\u3057\u3066\u6442\u53d6\u3059\u308b\u3053\u3068\u3067\u808c\u306e\u4fdd\u8b77\u80fd\u529b\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u53c2\u8003\u6587\u732e<\/strong>\uff1a<br>Nichols, J. A., &amp; Katiyar, S. K. (2010). Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and DNA repair mechanisms. <em>Archives of Dermatological Research<\/em>, 302(2), 71\u201383.<br><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19924469\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/19924469\/<br><\/a><\/li>\n<\/ul>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p 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https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/22095577_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u7d2b\u5916\u7dda\u5bfe\u7b56\u306f\u5e74\u9f62\u306b\u5fdc\u3058\u3066\u914d\u616e\u3059\u3079\u304d\u30dd\u30a4\u30f3\u30c8\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 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class=\"wp-block-heading\"><strong>\u9ad8\u9f62\u8005<\/strong><\/h3>\n\n\n\n<p>\u9ad8\u9f62\u306b\u306a\u308b\u3068\u76ae\u819a\u306e\u518d\u751f\u529b\u304c\u4f4e\u4e0b\u3057\u3001\u7d2b\u5916\u7dda\u30c0\u30e1\u30fc\u30b8\u306e\u4fee\u5fa9\u80fd\u529b\u304c\u8457\u3057\u304f\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u30b7\u30df\u3084\u305d\u3070\u304b\u3059\u3068\u3044\u3063\u305f\u5149\u8001\u5316\u306e\u84c4\u7a4d\u3082\u9855\u8457\u306b\u306a\u308b\u305f\u3081\u3001\u79cb\u51ac\u306e\u5bfe\u7b56\u3053\u305d\u91cd\u8981\u3067\u3059\u3002\u7279\u306b\u4e7e\u71e5\u3068\u7d2b\u5916\u7dda\u304c\u76f8\u4e57\u7684\u306b\u76ae\u819a\u30d0\u30ea\u30a2\u3092\u5f31\u4f53\u5316\u3055\u305b\u3001\u304b\u3086\u307f\u3084\u6e7f\u75b9\u3092\u5f15\u304d\u8d77\u3053\u3057\u3084\u3059\u304f\u306a\u308b\u305f\u3081\u3001\u4fdd\u6e7f\u3068UV\u30b1\u30a2\u3092\u4f75\u7528\u3059\u308b\u3053\u3068\u304c\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<p><strong>\u79cb\u51ac\u306e\u30b9\u30dd\u30fc\u30c4\u30fb\u30ec\u30b8\u30e3\u30fc\u3068\u7d2b\u5916\u7dda\u30ea\u30b9\u30af<\/strong><\/p>\n\n\n\n<p>\u79cb\u304b\u3089\u51ac\u306b\u304b\u3051\u3066\u306e\u30a2\u30a6\u30c8\u30c9\u30a2\u30a2\u30af\u30c6\u30a3\u30d3\u30c6\u30a3\u2015\u2015\u4f8b\u3048\u3070\u767b\u5c71\u3001\u30cf\u30a4\u30ad\u30f3\u30b0\u3001\u30e9\u30f3\u30cb\u30f3\u30b0\u3001\u30b9\u30ad\u30fc\u306a\u3069\u306f\u3001\u7d2b\u5916\u7dda\u306e\u898b\u843d\u3068\u3055\u308c\u304c\u3061\u306a\u30ea\u30b9\u30af\u3092\u4f34\u3044\u307e\u3059\u3002\u7279\u306b\u9ad8\u5730\u3067\u306e\u6d3b\u52d5\u3067\u306f\u6a19\u9ad8\u304c\u4e0a\u304c\u308b\u3054\u3068\u306bUV-B\u306e\u7167\u5c04\u91cf\u304c\u5897\u52a0\u3057\u3001\u51ac\u5834\u3067\u3082\u65e5\u713c\u3051\u3084\u5149\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5b9f\u969b\u3001\u6a19\u9ad81000m\u3054\u3068\u306b\u7d2b\u5916\u7dda\u91cf\u306f\u7d0410\u301c12\uff05\u5897\u52a0\u3059\u308b\u3068\u8a00\u308f\u308c\u3066\u304a\u308a\u3001\u4f8b\u3048\u3070\u5bcc\u58eb\u5c71\u4e94\u5408\u76ee\uff08\u7d042300m\uff09\u3067\u306f\u3001\u5730\u4e0a\u3068\u6bd4\u3079\u306620\u301c25\uff05\u591a\u304f\u306e\u7d2b\u5916\u7dda\u3092\u6d74\u3073\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u96ea\u9762\u3067\u306e\u7d2b\u5916\u7dda\u53cd\u5c04\u7387\u3082\u975e\u5e38\u306b\u9ad8\u304f\uff08\u6700\u5927\u306780\uff05\u4ee5\u4e0a\uff09\u3001\u9854\u306e\u4e0b\u304b\u3089\u7167\u5c04\u3055\u308c\u308b\u201c\u9006\u65e5\u713c\u3051\u201d\u306e\u30ea\u30b9\u30af\u3082\u7121\u8996\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<p><strong>\u5316\u7ca7\u54c1\u3068\u7d2b\u5916\u7dda\u9632\u5fa1\u306e\u6700\u65b0\u30c8\u30ec\u30f3\u30c9<\/strong><\/p>\n\n\n\n<p>\u7d2b\u5916\u7dda\u5bfe\u7b56\u306f\u30b9\u30ad\u30f3\u30b1\u30a2\u88fd\u54c1\u9078\u3073\u3067\u3082\u9032\u5316\u3092\u7d9a\u3051\u3066\u3044\u307e\u3059\u3002\u5f93\u6765\u306fSPF\u30fbPA\u306e\u6570\u5024\u306b\u6ce8\u76ee\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u304c\u3001\u8fd1\u5e74\u3067\u306f\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u30ab\u30c3\u30c8\u6a5f\u80fd\u3084\u8fd1\u8d64\u5916\u7dda\uff08IR-A\uff09\u30d6\u30ed\u30c3\u30af\u6280\u8853\u304c\u52a0\u308f\u308a\u3001\u3088\u308a\u5305\u62ec\u7684\u306a\u5149\u9632\u5fa1\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>1. \u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u5bfe\u7b56<\/strong><\/p>\n\n\n\n<p>\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\uff08HEV\uff09\u306f\u30c7\u30b8\u30bf\u30eb\u6a5f\u5668\u304b\u3089\u767a\u305b\u3089\u308c\u308b\u53ef\u8996\u5149\u7dda\u3067\u3001\u7d2b\u5916\u7dda\u3068\u7570\u306a\u308a\u30a8\u30cd\u30eb\u30ae\u30fc\u306f\u4f4e\u3044\u3082\u306e\u306e\u3001\u6162\u6027\u7684\u306a\u7167\u5c04\u306b\u3088\u3063\u3066\u30e1\u30e9\u30cb\u30f3\u7523\u751f\u3084\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u89e3\u9175\u7d20\uff08MMP-1\uff09\u306e\u767a\u73fe\u3092\u8a98\u5c0e\u3057\u3001\u30b7\u30df\u3084\u3057\u308f\u306e\u539f\u56e0\u3068\u306a\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u4f8b\uff1a<\/p>\n\n\n\n<p>Nakashima, Y. et al. (2017). Blue light-induced oxidative stress and DNA damage in human keratinocytes. Journal of Dermatological Science, 86(2), 123\u2013131.<\/p>\n\n\n\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28502643\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28502643<\/a><\/p>\n\n\n\n<p><strong>2. 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class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/3676484_m-1024x683.jpg\" alt=\"\n\u7814\u7a76\u30fb\u79d1\u5b66\u8005\u30a4\u30e1\u30fc\u30b8\" class=\"wp-image-153\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/3676484_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/3676484_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/3676484_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/3676484_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/3676484_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u7d2b\u5916\u7dda\u3068\u808c\u306e\u5065\u5eb7\u3092\u8a9e\u308b\u3046\u3048\u3067\u3001\u5fd8\u308c\u3066\u306f\u306a\u3089\u306a\u3044\u306e\u304c\u76ae\u819a\u5e38\u5728\u83cc\u306e\u5b58\u5728\u3067\u3059\u3002\u79cb\u51ac\u306f\u6c17\u6e29\u3068\u6e7f\u5ea6\u306e\u4f4e\u4e0b\u306b\u3088\u308a\u3001\u76ae\u819a\u306e\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u306e\u591a\u69d8\u6027\u304c\u6e1b\u5c11\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u305d\u3053\u306b\u7d2b\u5916\u7dda\u30c0\u30e1\u30fc\u30b8\u304c\u52a0\u308f\u308b\u3053\u3068\u3067\u3001\u708e\u75c7\u3084\u30c8\u30e9\u30d6\u30eb\u306e\u30ea\u30b9\u30af\u304c\u3055\u3089\u306b\u5897\u52a0\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001\u7d2b\u5916\u7dda\u66dd\u9732\u306b\u3088\u3063\u3066\u6709\u5bb3\u306aStaphylococcus aureus\uff08\u9ec4\u8272\u30d6\u30c9\u30a6\u7403\u83cc\uff09\u306e\u512a\u4f4d\u6027\u304c\u9ad8\u307e\u308a\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3084\u6e7f\u75b9\u306e\u60aa\u5316\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u8981\u3067\u3042\u308b**\u8868\u76ae\u30d6\u30c9\u30a6\u7403\u83cc\uff08Staphylococcus epidermidis\uff09**\u304c\u6e1b\u5c11\u3059\u308b\u3053\u3068\u3067\u3001\u5916\u7684\u523a\u6fc0\u3078\u306e\u611f\u53d7\u6027\u304c\u9ad8\u307e\u308b\u50be\u5411\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u3046\u3057\u305f\u76ae\u819a\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30fc\u30e0\u306e\u4fdd\u5168\u306b\u306f\u3001\u6d17\u3044\u3059\u304e\u3092\u907f\u3051\u308b\u3053\u3068\u3001\u904e\u5ea6\u306a\u30a2\u30eb\u30b3\u30fc\u30eb\u30fb\u754c\u9762\u6d3b\u6027\u5264\u3092\u542b\u3080\u88fd\u54c1\u306e\u4f7f\u7528\u3092\u63a7\u3048\u308b\u3053\u3068\u3001\u3055\u3089\u306b\u306f\u30d7\u30ed\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3084\u30d7\u30ec\u30d0\u30a4\u30aa\u30c6\u30a3\u30af\u30b9\u3092\u53d6\u308a\u5165\u308c\u308b\u98df\u751f\u6d3b\u306e\u5de5\u592b\u304c\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<p><strong>\u5b63\u7bc0\u6027\u7d2b\u5916\u7dda\u5bfe\u7b56\u306b\u304a\u3051\u308b\u30b0\u30ed\u30fc\u30d0\u30eb\u52d5\u5411<\/strong><\/p>\n\n\n\n<p>\u4e16\u754c\u7684\u306b\u3082\u3001\u7d2b\u5916\u7dda\u5bfe\u7b56\u306f\u300c\u590f\u9650\u5b9a\u300d\u304b\u3089\u300c\u5e74\u9593\u6226\u7565\u300d\u3078\u3068\u610f\u8b58\u304c\u5909\u5316\u3057\u3066\u3044\u307e\u3059\u3002\u6b27\u7c73\u306e\u76ae\u819a\u79d1\u5b66\u4f1a\u3067\u306f\u3001\u3059\u3067\u306b2000\u5e74\u4ee3\u521d\u982d\u304b\u3089\u5e74\u4e2d\u306e\u7d2b\u5916\u7dda\u9632\u5fa1\u304c\u76ae\u819a\u304c\u3093\u4e88\u9632\u306e\u91cd\u8981\u306a\u67f1\u3068\u3057\u3066\u4f4d\u7f6e\u3065\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u30a2\u30e1\u30ea\u30ab\u76ae\u819a\u79d1\u5b66\u4f1a\uff08AAD\uff09\u306f\u3001\u300cUV\u306f\u5e74\u4e2d\u964d\u308a\u6ce8\u3044\u3067\u3044\u308b\u305f\u3081\u3001\u51ac\u3067\u3042\u3063\u3066\u3082SPF30\u4ee5\u4e0a\u306e\u65e5\u713c\u3051\u6b62\u3081\u3092\u4f7f\u7528\u3059\u3079\u304d\u300d\u3068\u660e\u8a18\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u3067\u306f\u30b9\u30ad\u30f3\u30ad\u30e3\u30f3\u30b5\u30fc\u304c\u975e\u5e38\u306b\u591a\u3044\u305f\u3081\u3001\u5b50\u3069\u3082\u304b\u3089\u9ad8\u9f62\u8005\u307e\u3067\u306e\u7d2b\u5916\u7dda\u6559\u80b2\u3068\u5bfe\u7b56\u304c\u56fd\u3092\u6319\u3052\u3066\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u65e5\u672c\u3067\u3082\u74b0\u5883\u7701\u304c\u767a\u884c\u3059\u308b\u300c\u7d2b\u5916\u7dda\u74b0\u5883\u4fdd\u5065\u30de\u30cb\u30e5\u30a2\u30eb\u300d\u3084\u6c17\u8c61\u5e81\u306eUV\u30a4\u30f3\u30c7\u30c3\u30af\u30b9\u60c5\u5831\u304c\u3042\u308a\u3001\u4eca\u5f8c\u307e\u3059\u307e\u3059\u7d2b\u5916\u7dda\u5bfe\u7b56\u306e\u5553\u767a\u304c\u91cd\u8981\u306b\u306a\u308b\u3053\u3068\u306f\u9593\u9055\u3044\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u7d2b\u5916\u7dda\u3068\u773c\u3078\u306e\u5f71\u97ff\uff1a\u79cb\u51ac\u306b\u3082\u8981\u6ce8\u610f<\/strong><\/h2>\n\n\n\n<p>\u7d2b\u5916\u7dda\u306e\u5f71\u97ff\u306f\u76ae\u819a\u3060\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u76ee\u3082\u307e\u305f\u7d2b\u5916\u7dda\u306b\u3055\u3089\u3055\u308c\u308b\u3053\u3068\u3067\u3055\u307e\u3056\u307e\u306a\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3059\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002\u7279\u306b<strong>UV-B<\/strong>\u306f\u89d2\u819c\u3084\u6c34\u6676\u4f53\u306b\u5f37\u304f\u5438\u53ce\u3055\u308c\u3001\u708e\u75c7\u3084\u767d\u5185\u969c\u306e\u539f\u56e0\u306b\u306a\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3001<strong>UV-A<\/strong>\u306f\u900f\u904e\u6027\u304c\u9ad8\u304f\u3001\u7db2\u819c\u306b\u307e\u3067\u5230\u9054\u3057\u3046\u308b\u3053\u3068\u304b\u3089\u3001\u9577\u671f\u7684\u306b\u306f\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u75c7\u306e\u767a\u75c7\u306b\u3082\u95a2\u4e0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u79cb\u51ac\u306f\u592a\u967d\u304c\u4f4e\u3044\u4f4d\u7f6e\u306b\u3042\u308b\u305f\u3081\u3001\u65e5\u5149\u304c\u659c\u3081\u304b\u3089\u76ee\u306b\u5dee\u3057\u8fbc\u3080\u6642\u9593\u304c\u5897\u3048\u307e\u3059\u3002\u307e\u305f\u3001\u96ea\u9762\u3084\u6c34\u9762\u304b\u3089\u306e\u53cd\u5c04\u306b\u3088\u3063\u3066\u3001\u773c\u306b\u5165\u308b\u7d2b\u5916\u7dda\u91cf\u304c\u590f\u4ee5\u4e0a\u306b\u306a\u308b\u30b1\u30fc\u30b9\u3082\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u30a6\u30a3\u30f3\u30bf\u30fc\u30b9\u30dd\u30fc\u30c4\u3084\u91e3\u308a\u3001\u767b\u5c71\u306a\u3069\u3067\u306f\u3001\u773c\u306e\u4fdd\u8b77\u304c\u91cd\u8981\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u5bfe\u7b56\u3068\u3057\u3066\u306f\uff1a<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>UV\u30ab\u30c3\u30c8\u6a5f\u80fd\u4ed8\u304d\u30b5\u30f3\u30b0\u30e9\u30b9\u3084\u30b4\u30fc\u30b0\u30eb<\/strong>\u306e\u7740\u7528\uff08UV400\u8868\u793a\u304c\u76ee\u5b89\uff09<br><\/li>\n\n\n\n<li><strong>\u906e\u5149\u5e3d\u5b50<\/strong>\u3084<strong>\u30d0\u30a4\u30b6\u30fc<\/strong>\u306e\u4f7f\u7528<br><\/li>\n\n\n\n<li>\u9577\u6642\u9593\u306e\u5c4b\u5916\u6d3b\u52d5\u6642\u306b\u306f<strong>\u773c\u79d1\u7528\u306eUV\u5bfe\u7b56\u70b9\u773c\u6db2<\/strong>\u306e\u4f75\u7528\u3082\u691c\u8a0e<br><\/li>\n<\/ul>\n\n\n\n<p>\u8996\u899a\u5668\u5b98\u306b\u5bfe\u3059\u308b\u7d2b\u5916\u7dda\u306e\u5f71\u97ff\u306f\u84c4\u7a4d\u3055\u308c\u3001\u75c7\u72b6\u304c\u8868\u9762\u5316\u3059\u308b\u307e\u3067\u306b\u6642\u9593\u304c\u304b\u304b\u308b\u3053\u3068\u304c\u591a\u3044\u305f\u3081\u3001\u82e5\u5e74\u5c64\u3067\u3082\u4e88\u9632\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<hr 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https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/22839677_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" 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class=\"wp-block-heading\"><strong>\u30a8\u30d3\u30c7\u30f3\u30b9\u3068\u53c2\u8003\u8cc7\u6599<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Mouret, S. et al. (2006). Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation. <em>Proceedings of the National Academy of Sciences<\/em>, 103(37), 13765\u201313770.<br>https:\/\/www.pnas.org\/content\/103\/37\/13765<br><\/li>\n\n\n\n<li>Katiyar, S. K., et al. (1997). Green tea polyphenols treatment to human skin prevents formation of erythema induced by UV radiation. <em>Journal of Investigative Dermatology<\/em>, 108(4), 737\u2013742.<br><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/9097971\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/9097971\/<br><\/a><\/li>\n\n\n\n<li>Gonz\u00e1lez, S., et al. (2011). Polypodium leucotomos extract: a nutraceutical with photoprotective properties. <em>Journal of the American Academy of Dermatology<\/em>, 65(3), 528\u2013535.<br><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21839345\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/21839345\/<br><\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u306f\u3058\u3081\u306b\uff1a\u79cb\u51ac\u306e\u7d2b\u5916\u7dda\u304c\u3082\u305f\u3089\u3059\u898b\u3048\u306a\u3044\u30ea\u30b9\u30af 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