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https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/28036509_m-1.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u76ae\u819a\u79d1\u5b66\u7684\u306a\u7814\u7a76\u3067\u306f\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306e\u7167\u5c04\u306b\u3088\u308a\u3001\u808c\u306e\u6df1\u90e8\u3067\u6d3b\u6027\u9178\u7d20\uff08ROS\uff09\u306e\u767a\u751f\u304c\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5909\u5316\u304c\u8d77\u3053\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul 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class=\"wp-block-heading\"><strong>SOD2\u30fbGPX1\u306a\u3069\u306e\u6297\u9178\u5316\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u6d3b\u6027\u9178\u7d20\u306e\u51e6\u7406\u80fd\u529b\u306f\u3001SOD\uff08\u30b9\u30fc\u30d1\u30fc\u30aa\u30ad\u30b7\u30c9\u30b8\u30b9\u30e0\u30bf\u30fc\u30bc\uff09\u3001GPX\uff08\u30b0\u30eb\u30bf\u30c1\u30aa\u30f3\u30da\u30eb\u30aa\u30ad\u30b7\u30c0\u30fc\u30bc\uff09\u3001CAT\uff08\u30ab\u30bf\u30e9\u30fc\u30bc\uff09\u3068\u3044\u3063\u305f\u6297\u9178\u5316\u9175\u7d20\u306b\u4f9d\u5b58\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u9175\u7d20\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u306b\u5909\u7570\u3084\u591a\u578b\u304c\u3042\u308b\u5834\u5408\u3001\u4f53\u5185\u306e\u6297\u9178\u5316\u9632\u5fa1\u304c\u5f31\u304f\u306a\u308a\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3084\u7d2b\u5916\u7dda\u306b\u3088\u3063\u3066\u767a\u751f\u3057\u305fROS\uff08\u6d3b\u6027\u9178\u7d20\u7a2e\uff09\u306e\u9664\u53bb\u304c\u9045\u308c\u3001\u7d30\u80de\u30c0\u30e1\u30fc\u30b8\u304c\u84c4\u7a4d\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\uff08PMID: 24122977\uff09\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001SOD2\u907a\u4f1d\u5b50\u306ers4880\u3068\u3044\u3046\u4e00\u5869\u57fa\u591a\u578b\uff08SNP\uff09\u306f\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u5185\u3067\u306e\u6d3b\u6027\u9178\u7d20\u51e6\u7406\u80fd\u529b\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u3053\u306eSNP\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u3063\u3066\u306f\u3001\u5149\u9178\u5316\u30c0\u30e1\u30fc\u30b8\u3078\u306e\u8010\u6027\u306b\u500b\u4eba\u5dee\u304c\u51fa\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>MC1R\u30fbTYR\u306a\u3069\u306e\u8272\u7d20\u4ee3\u8b1d\u95a2\u9023\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u3088\u3063\u3066\u8a98\u5c0e\u3055\u308c\u308b\u8272\u7d20\u6c88\u7740\u306e\u3057\u3084\u3059\u3055\u306b\u306f\u3001\u30e1\u30e9\u30cb\u30f3\u4ee3\u8b1d\u306e\u500b\u4eba\u5dee\u3082\u5927\u304d\u304f\u95a2\u4e0e\u3057\u307e\u3059\u3002MC1R\uff08\u30e1\u30e9\u30ce\u30b3\u30eb\u30c1\u30f31\u53d7\u5bb9\u4f53\uff09\u3084TYR\uff08\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\uff09\u306a\u3069\u306e\u907a\u4f1d\u5b50\u306f\u3001\u30e1\u30e9\u30cb\u30f3\u306e\u751f\u6210\u91cf\u3084\u30bf\u30a4\u30d7\uff08\u30e6\u30fc\u30e1\u30e9\u30cb\u30f3 vs 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15317791\uff09\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306a\u80cc\u666f\u3092\u6301\u3064\u4eba\u306f\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u3088\u308b\u304f\u3059\u307f\u3084\u8272\u7d20\u6c88\u7740\u304c\u9577\u5f15\u304f\u3053\u3068\u304c\u591a\u304f\u3001\u65e5\u5e38\u7684\u306a\u5149\u9632\u5fa1\u306e\u5fb9\u5e95\u3084\u3001\u30a4\u30f3\u30ca\u30fc\u30b1\u30a2\u306b\u3088\u308b\u6297\u9178\u5316\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u7279\u306b\u91cd\u8981\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u30d0\u30ea\u30a2\u6a5f\u80fd\u3068\u708e\u75c7\u611f\u53d7\u6027\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50<\/strong><\/h3>\n\n\n\n<p>\u76ae\u819a\u30d0\u30ea\u30a2\u306e\u5f37\u5ea6\u3084\u3001\u708e\u75c7\u306e\u8d77\u3053\u308a\u3084\u3059\u3055\u3082\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3078\u306e\u611f\u53d7\u6027\u3092\u5de6\u53f3\u3059\u308b\u56e0\u5b50\u306e\u3072\u3068\u3064\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001FLG\uff08\u30d5\u30a3\u30e9\u30b0\u30ea\u30f3\uff09\u907a\u4f1d\u5b50\u306f\u76ae\u819a\u306e\u30d0\u30ea\u30a2\u69cb\u9020\u3092\u7dad\u6301\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30b3\u30fc\u30c9\u3057\u3066\u304a\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u3068\u3001\u89d2\u8cea\u5c64\u306e\u6c34\u5206\u4fdd\u6301\u529b\u304c\u4f4e\u4e0b\u3057\u3001\u523a\u6fc0\u7269\u8cea\u304c\u4fb5\u5165\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u3084\u7d2b\u5916\u7dda\u306b\u3088\u308b\u523a\u6fc0\u306b\u5bfe\u3057\u3066\u3082\u3001\u708e\u75c7\u53cd\u5fdc\u304c\u5f37\u304f\u51fa\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001IL-6\u3084TNF-\u03b1\u3068\u3044\u3063\u305f\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3092\u8abf\u7bc0\u3059\u308b\u907a\u4f1d\u5b50\u7fa4\u306e\u6d3b\u6027\u72b6\u614b\u3082\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u3088\u308b\u5fae\u5f31\u306a\u708e\u75c7\u3092\u3069\u306e\u7a0b\u5ea6\u5897\u5e45\u3055\u305b\u308b\u304b\u306b\u95a2\u308f\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u907a\u4f1d\u60c5\u5831\u306b\u57fa\u3065\u3044\u305fUV\u5bfe\u7b56\u306e\u672a\u6765<\/strong><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/2154675_m-1024x683.jpg\" alt=\"\n\" class=\"wp-image-641\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/2154675_m-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/2154675_m-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/2154675_m-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/2154675_m-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/2154675_m.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306a\u907a\u4f1d\u7684\u306a\u80cc\u666f\u3092\u628a\u63e1\u3059\u308b\u3053\u3068\u3067\u3001\u5358\u306a\u308b\u300c\u808c\u306e\u8272\u300d\u3084\u300c\u4f53\u8cea\u300d\u306b\u57fa\u3065\u304fUV\u5bfe\u7b56\u304b\u3089\u3001\u3088\u308a\u7cbe\u5bc6\u306a\u300c\u30d1\u30fc\u30bd\u30ca\u30e9\u30a4\u30ba\u30c9\u30fb\u30d5\u30a9\u30c8\u30d7\u30ed\u30c6\u30af\u30b7\u30e7\u30f3\u300d\u3078\u306e\u79fb\u884c\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u81ea\u5206\u306eSOD2\u306b\u591a\u578b\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u308c\u3070\u3001\u30a2\u30b9\u30bf\u30ad\u30b5\u30f3\u30c1\u30f3\u3084\u30d3\u30bf\u30df\u30f3C\u306e\u6442\u53d6\u3092\u610f\u8b58\u7684\u306b\u5f37\u5316\u3057\u305f\u308a\u3001MC1R\u306e\u5909\u7570\u304c\u78ba\u8a8d\u3055\u308c\u305f\u5834\u5408\u306b\u306f\u3001\u65e5\u713c\u3051\u6b62\u3081\u306b\u52a0\u3048\u3066\u7f8e\u767d\u7cfb\u306e\u5185\u670d\u30b1\u30a2\u3084\u6297\u9178\u5316\u30b1\u30a2\u3092\u7a4d\u6975\u7684\u306b\u53d6\u308a\u5165\u308c\u308b\u5224\u65ad\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u307e\u3067\u66d6\u6627\u3060\u3063\u305f\u300c\u81ea\u5206\u306b\u5408\u3046UV\u30b1\u30a2\u300d\u306e\u6307\u91dd\u304c\u3001\u907a\u4f1d\u5b50\u3068\u3044\u3046\u5ba2\u89b3\u7684\u306a\u6307\u6a19\u3092\u5f97\u308b\u3053\u3068\u3067\u3001\u660e\u78ba\u304b\u3064\u500b\u5225\u5bfe\u5fdc\u578b\u306b\u9032\u5316\u3057\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u5bfe\u3059\u308b\u6210\u5206\u5225\u9632\u5fa1\u6226\u7565<\/strong><\/h2>\n\n\n\n<p>\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u3088\u308b\u808c\u30c0\u30e1\u30fc\u30b8\u306b\u5bfe\u51e6\u3059\u308b\u306b\u306f\u3001\u300c\u5916\u7528\uff0b\u5185\u670d\u300d\u306e\u4e21\u9762\u304b\u3089\u306e\u6226\u7565\u304c\u91cd\u8981\u3067\u3059\u3002\u8fd1\u5e74\u3067\u306f\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u7279\u5316\u3057\u305f\u30b9\u30ad\u30f3\u30b1\u30a2\u6210\u5206\u3084\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u6210\u5206\u3082\u591a\u304f\u767b\u5834\u3057\u3066\u304a\u308a\u3001\u305d\u308c\u305e\u308c\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u5bfe\u7b56\u304c\u53ef\u80fd\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u5916\u7528\u6210\u5206\u306e\u9078\u3073\u65b9\u3068\u7279\u5fb4<\/strong><\/h3>\n\n\n\n<p><strong>1. \u30eb\u30c6\u30a4\u30f3\u30fb\u30bc\u30a2\u30ad\u30b5\u30f3\u30c1\u30f3\uff1a<\/strong><strong><br><\/strong> 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UVA\u30fbUVB\u3060\u3051\u3067\u306a\u304f\u3001\u53ef\u8996\u5149\u7dda\u57df\u306b\u308f\u305f\u308b\u5e83\u57df\u30b9\u30da\u30af\u30c8\u30eb\u3092\u30d6\u30ed\u30c3\u30af\u3067\u304d\u308b\u7269\u7406\u7684\u9632\u5fa1\u6210\u5206\u3067\u3059\u3002\u30ce\u30f3\u30b1\u30df\u30ab\u30eb\u304b\u3064\u808c\u3078\u306e\u523a\u6fc0\u304c\u5c11\u306a\u3044\u305f\u3081\u3001\u654f\u611f\u808c\u3067\u3082\u4f7f\u7528\u3057\u3084\u3059\u304f\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u9632\u5fa1\u306b\u3082\u5bfe\u5fdc\u3067\u304d\u308b\u51e6\u65b9\u304c\u5897\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>3. \u30d5\u30e9\u30fc\u30ec\u30f3\u30fb\u30d3\u30bf\u30df\u30f3C\u8a98\u5c0e\u4f53\uff1a<\/strong><strong><br><\/strong> 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DNA\u4fee\u5fa9\u3092\u52a9\u3051\u3001\u5149\u30c0\u30e1\u30fc\u30b8\u306b\u3088\u3063\u3066\u8a98\u5c0e\u3055\u308c\u308b\u708e\u75c7\u53cd\u5fdc\u3092\u6291\u5236\u3059\u308b\u6210\u5206\u3067\u3059\u3002\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306e\u7167\u5c04\u306b\u3088\u3063\u3066\u4e71\u308c\u305f\u8868\u76ae\u30d0\u30ea\u30a2\u6a5f\u80fd\u306e\u56de\u5fa9\u306b\u3082\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u304a\u308a\u3001\u5149\u8001\u5316\u5168\u822c\u306e\u4e88\u9632\u306b\u5f79\u7acb\u3061\u307e\u3059\uff08PMID: 26376606\uff09\u3002<\/p>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u5185\u670d\u6210\u5206\u306b\u3088\u308b\u30a4\u30f3\u30ca\u30fc\u30b1\u30a2<\/strong><\/h3>\n\n\n\n<p><strong>1. \u30a2\u30b9\u30bf\u30ad\u30b5\u30f3\u30c1\u30f3\uff1a<\/strong><strong><br><\/strong> \u8102\u6eb6\u6027\u6297\u9178\u5316\u7269\u8cea\u3067\u3042\u308a\u3001\u7d30\u80de\u819c\u306b\u76f4\u63a5\u5165\u308a\u8fbc\u3093\u3067\u9178\u5316\u30c0\u30e1\u30fc\u30b8\u3092\u9632\u304e\u307e\u3059\u3002\u3068\u304f\u306b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u4fdd\u8b77\u4f5c\u7528\u304c\u5f37\u304f\u3001\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u30a8\u30cd\u30eb\u30ae\u30fc\u4ee3\u8b1d\u969c\u5bb3\u306b\u3082\u5bfe\u51e6\u53ef\u80fd\u3067\u3059\u3002\u7d2b\u5916\u7dda\u5bfe\u7b56\u3068\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u5bfe\u7b56\u3092\u517c\u306d\u308b\u4e07\u80fd\u6210\u5206\u3068\u3044\u3048\u307e\u3059\uff08PMID: 27092491\uff09\u3002<\/p>\n\n\n\n<p><strong>2. \u30eb\u30c6\u30a4\u30f3\u30fb\u30bc\u30a2\u30ad\u30b5\u30f3\u30c1\u30f3\uff08\u5185\u670d\uff09\uff1a<\/strong><strong><br><\/strong> 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srcset=\"https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/4446199_m-1-1024x683.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/4446199_m-1-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/4446199_m-1-768x512.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/4446199_m-1-1536x1024.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/generio\/wp-content\/uploads\/2025\/05\/4446199_m-1.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u30d6\u30eb\u30fc\u30e9\u30a4\u30c8\u5bfe\u7b56\u306b\u304a\u3044\u3066\u306f\u3001\u300c\u5149\u3092\u9632\u3050\u300d\u6210\u5206\u3068\u300c\u9178\u5316\u3092\u6291\u3048\u308b\u300d\u6210\u5206\u306e\u4e21\u65b9\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u3055\u3089\u306b\u3001\u81ea\u5206\u306e\u808c\u8cea\u3084\u907a\u4f1d\u7684\u7279\u6027\u306b\u5408\u308f\u305b\u3066\u6210\u5206\u3092\u9078\u3076\u3053\u3068\u3067\u3001\u526f\u4f5c\u7528\u3084\u523a\u6fc0\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u306a\u304c\u3089\u3001\u6700\u5927\u9650\u306e\u52b9\u679c\u3092\u5f15\u304d\u51fa\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>[post_category_custom_html]<\/p>\n\n\n\n<h2 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