{"id":11450,"date":"2025-05-26T03:24:51","date_gmt":"2025-05-26T03:24:51","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/?p=11450"},"modified":"2025-05-29T03:28:18","modified_gmt":"2025-05-29T03:28:18","slug":"white-hair-science-aging-stress","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/white-hair-science-aging-stress\/","title":{"rendered":"\u767d\u9aea\u306f\u8001\u3044\u306e\u30b5\u30a4\u30f3\u3058\u3083\u306a\u3044\uff1f\u79d1\u5b66\u304c\u660e\u304b\u3059\u9aea\u306e\u8272\u3068\u5fc3\u3068\u4f53\u306e\u6df1\u3044\u95a2\u4fc2"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong>\u7b2c\u4e00\u7ae0\uff1a\u767d\u9aea\u306f\u8001\u5316\u306e\u300c\u8a3c\u62e0\u54c1\u300d\u304b\u3001\u305d\u308c\u3068\u3082\u751f\u547d\u306e\u8db3\u8de1\u304b<\/strong><\/h2>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-content-justification-center is-layout-flex wp-container-core-group-is-layout-1 wp-block-group-is-layout-flex\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/05\/32281632_s.jpg\" alt=\"\u9aea\u3092\u6307\u3067\u305d\u3063\u3068\u304b\u304d\u4e0a\u3052\u3066\u8033\u5143\u3092\u898b\u305b\u308b\u5973\u6027\u3002\u767d\u9aea\u306e\u6709\u7121\u3084\u982d\u76ae\u306e\u5909\u5316\u306b\u6c17\u3065\u304f\u65e5\u5e38\u306e\u4e00\u77ac\u3092\u5207\u308a\u53d6\u3063\u305f\u30a4\u30e1\u30fc\u30b8\uff5c\u767d\u9aea\u3068\u6bdb\u5305\u306e\u79d1\u5b66\u7684\u30e1\u30ab\u30cb\u30ba\u30e0\u89e3\u8aac\u8a18\u4e8b\u3088\u308a\" class=\"wp-image-11461\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/05\/32281632_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/05\/32281632_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/05\/32281632_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div><\/div>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u4eba\u751f\u306b\u304a\u3044\u3066\u3001\u93e1\u306b\u6620\u308b\u81ea\u5206\u306e\u59ff\u304c\u5909\u5316\u3057\u3066\u3044\u304f\u3053\u3068\u307b\u3069\u3001\u6642\u9593\u306e\u6d41\u308c\u3092\u5b9f\u611f\u3055\u305b\u308b\u77ac\u9593\u306f\u306a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3042\u308b\u671d\u3075\u3068\u3001\u9aea\u306e\u4e2d\u306b\u3072\u3068\u7b4b\u306e\u767d\u3092\u898b\u3064\u3051\u305f\u3068\u304d\u3001\u591a\u304f\u306e\u4eba\u304c\u300c\u8001\u3044\u300d\u3068\u3044\u3046\u8a00\u8449\u3092\u521d\u3081\u3066\u610f\u8b58\u3057\u307e\u3059\u3002\u767d\u9aea\u3001\u305d\u308c\u306f\u8ab0\u3082\u304c\u907f\u3051\u3089\u308c\u306a\u3044\u52a0\u9f62\u306e\u8a3c\u3001\u305d\u3046\u4fe1\u3058\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3051\u308c\u3069\u3082\u3001\u79d1\u5b66\u306e\u773c\u5dee\u3057\u3067\u3053\u306e\u73fe\u8c61\u3092\u3058\u3063\u304f\u308a\u3068\u898b\u3064\u3081\u76f4\u3059\u3068\u3001\u305d\u3053\u306b\u306f\u5358\u306a\u308b\u300c\u8272\u306e\u55aa\u5931\u300d\u3067\u306f\u306a\u3044\u3001\u9a5a\u304f\u307b\u3069\u8907\u96d1\u3067\u52d5\u7684\u306a\u751f\u547d\u306e\u55b6\u307f\u304c\u96a0\u3055\u308c\u3066\u3044\u305f\u306e\u3067\u3059\u3002\u767d\u9aea\u306f\u9759\u7684\u306a\u7d42\u7740\u70b9\u3067\u306f\u306a\u304f\u3001\u3080\u3057\u308d\u6bdb\u5305\uff08\u3082\u3046\u307b\u3046\uff1aHair Follicle\uff09\u3068\u3044\u3046\u5c0f\u3055\u306a\u5668\u5b98\u306e\u4e2d\u3067\u4eca\u3082\u9032\u884c\u3059\u308b\u300c\u751f\u306e\u30d7\u30ed\u30bb\u30b9\u300d\u2015\u2015\u3059\u306a\u308f\u3061\u7d30\u80de\u6d3b\u52d5\u3001\u4ee3\u8b1d\u3001\u518d\u751f\u3001\u305d\u3057\u3066\u74b0\u5883\u3068\u306e\u5bfe\u8a71\u2015\u2015\u305d\u306e\u6700\u524d\u7dda\u306e\u8a18\u9332\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u7269\u8a9e\u306f\u3001\u7d30\u80de\u306e\u3055\u3055\u3084\u304d\u306b\u8033\u3092\u50be\u3051\u308b\u3053\u3068\u304b\u3089\u59cb\u307e\u308a\u307e\u3059\u3002\u79d1\u5b66\u8005\u305f\u3061\u306f\u9855\u5fae\u93e1\u3092\u8997\u304d\u8fbc\u307f\u3001DNA\u3084\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u767a\u73fe\u3092\u89e3\u6790\u3057\u3001\u767d\u9aea\u3068\u3044\u3046\u8b0e\u3092\u89e3\u304d\u660e\u304b\u305d\u3046\u3068\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u672c\u7a3f\u3067\u306f\u305d\u306e\u7814\u7a76\u6210\u679c\u3092\u3001\u7269\u8a9e\u3068\u3057\u3066\u7d21\u304e\u306a\u304c\u3089\u4e01\u5be7\u306b\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u5c02\u9580\u5bb6\u306e\u65b9\u306b\u306f\u79d1\u5b66\u7684\u77e5\u898b\u306e\u6df1\u307f\u3092\u3001\u4e00\u822c\u306e\u8aad\u8005\u306b\u306f\u81ea\u5206\u306e\u9aea\u306b\u5bbf\u308b\u300c\u751f\u304d\u305f\u6b74\u53f2\u300d\u306e\u4e00\u7aef\u3092\u611f\u3058\u3066\u3044\u305f\u3060\u3051\u308b\u3088\u3046\u3001\u3067\u304d\u308b\u304b\u304e\u308a\u6a4b\u6e21\u3057\u3092\u8a66\u307f\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u7b2c\u4e8c\u7ae0\uff1a\u767d\u9aea\u306f\u3080\u3057\u308d\u300c\u6d3b\u767a\u306a\u9aea\u300d\u3060\u3063\u305f\u2014\u2014\u6210\u9577\u3068\u8001\u5316\u306e\u76ae\u8089\u306a\u95a2\u4fc2<\/strong><\/h2>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-content-justification-center is-layout-flex wp-container-core-group-is-layout-2 wp-block-group-is-layout-flex\"><div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/05\/31716946_s.jpg\" alt=\"\u9ed2\u9aea\u3092\u624b\u306e\u3072\u3089\u3068\u89aa\u6307\u3067\u3064\u307e\u307f\u3001\u9577\u304f\u5782\u308c\u305f\u9aea\u3092\u898b\u3064\u3081\u308b\u5973\u6027\u306e\u5f8c\u308d\u59ff\u3002\u9aea\u8cea\u3084\u8272\u7d20\u306e\u5909\u5316\u3092\u610f\u8b58\u3059\u308b\u9759\u304b\u306a\u77ac\u9593\uff5c\u767d\u9aea\u3068\u6bdb\u9aea\u69cb\u9020\u306e\u79d1\u5b66\u7684\u89e3\u8aac\u30b3\u30e9\u30e0\u3088\u308a\" class=\"wp-image-11464\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/05\/31716946_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/05\/31716946_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/05\/31716946_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div><\/div>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u300c\u767d\u9aea\uff1d\u8001\u5316\u3057\u305f\u5f31\u3044\u9aea\u300d\u3068\u3044\u3046\u5148\u5165\u89b3\u304c\u3001\u6700\u65b0\u306e\u7814\u7a76\u306b\u3088\u3063\u3066\u8986\u3055\u308c\u3088\u3046\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u4eba\u7537\u6027\u306e\u982d\u76ae\u304b\u3089\u63a1\u53d6\u3055\u308c\u305f\u9aea\u306e\u6bdb\u3092\u8abf\u3079\u305f\u3068\u3053\u308d\u3001\u767d\u9aea\u306f\u9ed2\u9aea\u3088\u308a\u3082\u300c\u592a\u304f\u300d\u300c\u4f38\u3073\u308b\u901f\u5ea6\u304c\u65e9\u3044\u300d\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u305f\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u89b3\u5bdf\u7d50\u679c\u3092\u88cf\u3065\u3051\u308b\u305f\u3081\u3001\u6bdb\u6839\u304b\u3089\u63a1\u53d6\u3057\u305fRNA\u3092\u4f7f\u3063\u3066\u7db2\u7f85\u7684\u306a\u907a\u4f1d\u5b50\u767a\u73fe\u89e3\u6790\uff08\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u89e3\u6790\uff09\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002\u3059\u308b\u3068\u3001\u767d\u9aea\u306e\u6bdb\u5305\u3067\u306f\u30b1\u30e9\u30c1\u30f3\uff08KRT\uff09\u304a\u3088\u3073\u30b1\u30e9\u30c1\u30f3\u95a2\u9023\u30bf\u30f3\u30d1\u30af\u8cea\uff08KRTAP\uff09\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u304c\u6709\u610f\u306b\u4e0a\u6607\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u30b1\u30e9\u30c1\u30f3\u3068\u306f\u3001\u9aea\u306e\u69cb\u9020\u305d\u306e\u3082\u306e\u3092\u5f62\u4f5c\u308b\u4e3b\u8981\u306a\u7e4a\u7dad\u72b6\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u3002KRT16\uff0812\u500d\u5897\uff09\u3001KRT6C\uff0810.4\u500d\u5897\uff09\u3001KRT83\uff087.7\u500d\u5897\uff09\u3068\u3044\u3063\u305f\u907a\u4f1d\u5b50\u306f\u3001\u9aea\u306e\u5f3e\u529b\u6027\u3084\u5f37\u5ea6\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u5358\u306b\u69cb\u9020\u304c\u5909\u308f\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u7269\u7406\u7684\u306a\u7279\u6027\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u6210\u9577\u56e0\u5b50\u306e\u767a\u73fe\u3082\u5909\u5316\u3057\u3066\u3044\u307e\u3057\u305f\u3002FGF5\uff08Fibroblast Growth Factor 5\uff09\u306f\u3001\u9aea\u306e\u6210\u9577\u671f\u3092\u7d42\u4e86\u3055\u305b\u308b\u30b7\u30b0\u30ca\u30eb\u3092\u51fa\u3059\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u304c\u3001\u767d\u9aea\u3067\u306f\u3053\u306e\u56e0\u5b50\u306e\u767a\u73fe\u304c\u6e1b\u5c11\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u4e00\u65b9\u3001\u6210\u9577\u4fc3\u9032\u56e0\u5b50\u3067\u3042\u308bFGF7\u306f\u5897\u52a0\u3057\u3066\u304a\u308a\u3001\u767d\u9aea\u306e\u6bdb\u5305\u304c\u300c\u6210\u9577\u30e2\u30fc\u30c9\u300d\u306b\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3064\u307e\u308a\u3001\u767d\u9aea\u306f\u751f\u7406\u5b66\u7684\u306b\u300c\u8870\u3048\u305f\u9aea\u300d\u3067\u306f\u306a\u304f\u3001\u3080\u3057\u308d\u300c\u6d3b\u767a\u306b\u6210\u9577\u3057\u3066\u3044\u308b\u9aea\u300d\u3060\u3063\u305f\u306e\u3067\u3059\u3002\u3053\u306e\u9006\u8aac\u7684\u306a\u767a\u898b\u306f\u3001\u300c\u9aea\u304c\u6d3b\u767a\u306b\u6210\u9577\u3057\u3059\u304e\u308b\u3053\u3068\u3067\u3001\u8272\u7d20\u7d30\u80de\u306b\u904e\u5270\u306a\u8ca0\u8377\u304c\u304b\u304b\u308a\u3001\u30e1\u30e9\u30cb\u30f3\u306e\u4f9b\u7d66\u304c\u8ffd\u3044\u3064\u304b\u306a\u304f\u306a\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u300d\u3068\u3044\u3046\u65b0\u305f\u306a\u4eee\u8aac\u3092\u5c0e\u304d\u51fa\u3057\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u7b2c\u4e09\u7ae0\uff1a\u8272\u3092\u3064\u304b\u3055\u3069\u308b\u7d30\u80de\u306e\u4e00\u751f\u2014\u2014\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u8a95\u751f\u3068\u6b7b<\/strong><\/h2>\n\n\n\n<p>\u3067\u306f\u3001\u306a\u305c\u6d3b\u767a\u306b\u6210\u9577\u3059\u308b\u767d\u9aea\u306b\u3060\u3051\u3001\u8272\u7d20\u304c\u5931\u308f\u308c\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u305d\u306e\u9375\u3092\u63e1\u308b\u306e\u304c\u3001\u6bdb\u5305\u5185\u306b\u5b58\u5728\u3059\u308b\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\uff08Melanocyte\uff09\u3067\u3059\u3002\u3053\u306e\u8272\u7d20\u7d30\u80de\u306f\u3001\u9ed2\u3084\u8336\u8272\u306e\u8272\u7d20\u3067\u3042\u308b\u30e1\u30e9\u30cb\u30f3\u3092\u5408\u6210\u3057\u3001\u305d\u308c\u3092\u9aea\u306e\u6bdb\u306e\u89d2\u5316\u7d30\u80de\u306b\u4f9b\u7d66\u3059\u308b\u3053\u3068\u3067\u3001\u9aea\u306e\u8272\u3092\u6c7a\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u81ea\u4f53\u306f\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u5e79\u7d30\u80de\uff08Melanocyte Stem Cell, MSC\uff09\u304b\u3089\u4f9b\u7d66\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u5e79\u7d30\u80de\u306f\u6bdb\u5305\u306e\u300c\u30d0\u30eb\u30b8\u9818\u57df\u300d\u3068\u547c\u3070\u308c\u308b\u5834\u6240\u306b\u6f5c\u3093\u3067\u304a\u308a\u3001\u9aea\u306e\u6210\u9577\u3068\u3068\u3082\u306b\u5206\u5316\u3057\u3066\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u3068\u306a\u308a\u3001\u8272\u7d20\u3092\u4f5c\u308a\u51fa\u3059\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u5fc3\u7406\u7684\u30b9\u30c8\u30ec\u30b9\u3084\u9178\u5316\u30b9\u30c8\u30ec\u30b9\uff08\u6b21\u7ae0\u3067\u8a73\u8ff0\uff09\u306a\u3069\u306b\u3088\u308a\u3001MSC\u304c\u904e\u5270\u306b\u52d5\u54e1\u3055\u308c\u305f\u308a\u3001\u8aa4\u3063\u305f\u30bf\u30a4\u30df\u30f3\u30b0\u3067\u5206\u5316\u3057\u3066\u3057\u307e\u3046\u3068\u3001\u305d\u306e\u4f9b\u7d66\u304c\u67af\u6e07\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\uff08\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u306e\u4e00\u7a2e\uff09\u306f\u03b22\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d7\u5bb9\u4f53\uff08\u03b22AR\uff09\u3092\u4ecb\u3057\u3066MSC\u306b\u4f5c\u7528\u3057\u3001\u6c38\u4e45\u7684\u306a\u67af\u6e07\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u30de\u30a6\u30b9\u5b9f\u9a13\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001MITF\uff08Microphthalmia-associated Transcription Factor\uff09\u3068\u3044\u3046\u8ee2\u5199\u56e0\u5b50\u306f\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u751f\u5b58\u3068\u6a5f\u80fd\u7dad\u6301\u306b\u5fc5\u8981\u4e0d\u53ef\u6b20\u3067\u3042\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7570\u5e38\u3082\u767d\u9aea\u306e\u4e00\u56e0\u3068\u306a\u308a\u307e\u3059\u3002MITF\u306f\u8272\u7d20\u751f\u6210\u9175\u7d20\u3067\u3042\u308b\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\uff08TYR\uff09\u3084TRP1\u306a\u3069\u306e\u767a\u73fe\u3092\u8abf\u6574\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u7fa4\u304c\u540c\u6642\u306b\u6c88\u9ed9\u3059\u308b\u3053\u3068\u3067\u3001\u30e1\u30e9\u30cb\u30f3\u5408\u6210\u304c\u505c\u6b62\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u767d\u9aea\u306f\u5358\u306b\u300c\u8272\u304c\u629c\u3051\u305f\u9aea\u300d\u3067\u306f\u306a\u304f\u3001\u300c\u5e79\u7d30\u80de\u4f9b\u7d66\u306e\u7834\u7dbb\u300d\u3068\u300c\u8ee2\u5199\u5236\u5fa1\u306e\u7570\u5e38\u300d\u304c\u91cd\u306a\u3063\u305f\u3001\u7cbe\u7dfb\u306a\u751f\u7269\u5b66\u7684\u30d7\u30ed\u30bb\u30b9\u306e\u672b\u306b\u73fe\u308c\u308b\u73fe\u8c61\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u7b2c\u56db\u7ae0\uff1a\u898b\u3048\u306a\u3044\u6575\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u2014\u2014\u9aea\u306e\u4e2d\u3067\u8d77\u304d\u3066\u3044\u308b\u708e\u75c7\u3068\u640d\u50b7<\/strong><\/h2>\n\n\n\n<p>\u751f\u7269\u306b\u3068\u3063\u3066\u9178\u7d20\u306f\u4e0d\u53ef\u6b20\u306a\u5b58\u5728\u3067\u3059\u304c\u3001\u305d\u306e\u4ee3\u8b1d\u904e\u7a0b\u3067\u751f\u3058\u308b\u526f\u7523\u7269\u2015\u2015\u6d3b\u6027\u9178\u7d20\u7a2e\uff08Reactive Oxygen Species, ROS\uff09\u306f\u3001\u7d30\u80de\u306b\u6df1\u523b\u306a\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u308b\u5203\u3068\u3082\u306a\u308a\u307e\u3059\u3002\u7279\u306b\u6bdb\u5305\u5185\u306e\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306f\u3001\u30e1\u30e9\u30cb\u30f3\u5408\u6210\u306e\u904e\u7a0b\u305d\u306e\u3082\u306e\u304c\u9ad8\u3044\u9178\u5316\u8ca0\u8377\u3092\u751f\u307f\u51fa\u3059\u305f\u3081\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u975e\u5e38\u306b\u5f31\u3044\u7d30\u80de\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u767d\u9aea\u306e\u6bdb\u5305\u3092\u9855\u5fae\u93e1\u3067\u89b3\u5bdf\u3059\u308b\u3068\u3001\u30e1\u30e9\u30ce\u30bd\u30fc\u30e0\uff08\u30e1\u30e9\u30cb\u30f3\u3092\u8caf\u8535\u3059\u308b\u7d30\u80de\u5c0f\u5668\u5b98\uff09\u304c\u8457\u3057\u304f\u6e1b\u5c11\u3057\u3066\u304a\u308a\u3001\u6b8b\u5b58\u3059\u308b\u3082\u306e\u3082\u69cb\u9020\u7684\u306b\u7834\u58ca\u3055\u308c\u3001\u7a7a\u80de\u5316\uff08\u30d0\u30ad\u30e5\u30aa\u30fc\u30eb\u5f62\u6210\uff09\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u306f\u3001ROS\u306e\u84c4\u7a4d\u306b\u3088\u3063\u3066\u7d30\u80de\u304c\u5185\u90e8\u304b\u3089\u300c\u7126\u3052\u308b\u3088\u3046\u306b\u300d\u7834\u58ca\u3055\u308c\u3066\u3044\u308b\u8a3c\u62e0\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001ROS\u306e\u4e00\u7a2e\u3067\u3042\u308b\u904e\u9178\u5316\u6c34\u7d20\uff08H\u2082O\u2082\uff09\u306f\u3001\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u306e\u6d3b\u6027\u90e8\u4f4d\u3092\u9178\u5316\u3057\u3001\u9175\u7d20\u3092\u4e0d\u6d3b\u6027\u5316\u3055\u305b\u3066\u3057\u307e\u3046\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u901a\u5e38\u3067\u3042\u308c\u3070\u30ab\u30bf\u30e9\u30fc\u30bc\u3068\u3044\u3046\u9175\u7d20\u304cH\u2082O\u2082\u3092\u5206\u89e3\u3057\u3066\u304f\u308c\u307e\u3059\u304c\u3001\u767d\u9aea\u306e\u6bdb\u5305\u3067\u306f\u30ab\u30bf\u30e9\u30fc\u30bc\u306e\u767a\u73fe\u304c\u4f4e\u4e0b\u3057\u3066\u304a\u308a\u3001\u9632\u5fa1\u6a5f\u69cb\u304c\u7834\u7dbb\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u767d\u9aea\u306f\u7d30\u80de\u6b7b\u306e\u75d5\u8de1\u3067\u3042\u308b\u3068\u540c\u6642\u306b\u3001\u300c\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3068\u3044\u3046\u708e\u300d\u306b\u3088\u3063\u3066\u713c\u304b\u308c\u305f\u751f\u547d\u306e\u8a18\u9332\u3067\u3082\u3042\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u7b2c\u4e94\u7ae0\uff1a\u9aea\u306f\u4eba\u751f\u3092\u8a18\u9332\u3059\u308b\u2014\u2014\u767d\u9aea\u3068\u30b9\u30c8\u30ec\u30b9\u3001\u305d\u3057\u3066\u518d\u751f\u306e\u7269\u8a9e<\/strong><\/h2>\n\n\n\n<p>\u9577\u3089\u304f\u3001\u767d\u9aea\u306f\u4e0d\u53ef\u9006\u7684\u306a\u5909\u5316\u3067\u3042\u308b\u3068\u4fe1\u3058\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u30012021\u5e74\u306b\u767a\u8868\u3055\u308c\u305f\u753b\u671f\u7684\u306a\u7814\u7a76\u306b\u3088\u3063\u3066\u3001\u300c\u767d\u9aea\u304c\u9ed2\u9aea\u3078\u623b\u308b\u300d\u3068\u3044\u3046\u73fe\u8c61\u304c\u79d1\u5b66\u7684\u306b\u89b3\u5bdf\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u7814\u7a76\u3067\u306f\u300114\u4eba\u306e\u88ab\u9a13\u8005\u304b\u3089\u5f97\u3089\u308c\u305f\u5408\u8a08397\u672c\u306e\u6bdb\u9aea\u3092\u9ad8\u89e3\u50cf\u5ea6\u3067\u30b9\u30ad\u30e3\u30f3\u3057\u3001\u6bdb\u5e79\uff08\u9aea\u306e\u30b7\u30e3\u30d5\u30c8\uff09\u306b\u6cbf\u3063\u3066\u8272\u7d20\u30d1\u30bf\u30fc\u30f3\u3092\u6642\u9593\u8ef8\u3068\u3057\u3066\u53ef\u8996\u5316\u3057\u307e\u3057\u305f\u3002\u4eba\u9593\u306e\u9aea\u306f\u7d041\u30f6\u6708\u306b1cm\u4f38\u3073\u308b\u305f\u3081\u3001\u8272\u7d20\u306e\u5909\u5316\u306f\u305d\u306e\u307e\u307e\u6642\u9593\u306e\u7d4c\u904e\u3092\u793a\u3059\u300c\u6bdb\u306e\u5e74\u8868\u300d\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u9a5a\u304f\u3079\u304d\u3053\u3068\u306b\u3001\u767d\u2192\u9ed2\u3001\u9ed2\u2192\u767d\u3068\u3044\u3046\u8272\u306e\u6025\u6fc0\u306a\u5909\u5316\u304c\u6570\u65e5\u306e\u3046\u3061\u306b\u767a\u751f\u3057\u3066\u3044\u308b\u6bdb\u9aea\u304c\u8907\u6570\u78ba\u8a8d\u3055\u308c\u305f\u306e\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u5909\u5316\u306f\u3001\u88ab\u9a13\u8005\u304c\u8a18\u9332\u3057\u305f\u5fc3\u7406\u7684\u30b9\u30c8\u30ec\u30b9\u306e\u5909\u5316\u3068\u4e00\u81f4\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u305f\u3068\u3048\u3070\u3001\u7834\u5c40\u3084\u5931\u696d\u3068\u3044\u3063\u305f\u30b9\u30c8\u30ec\u30b9\u30d5\u30eb\u306a\u51fa\u6765\u4e8b\u306e\u76f4\u5f8c\u306b\u767d\u9aea\u5316\u304c\u9032\u884c\u3057\u3001\u6570\u9031\u9593\u5f8c\u306e\u5fc3\u5883\u306e\u56de\u5fa9\u3068\u3068\u3082\u306b\u518d\u3073\u8272\u304c\u623b\u308b\u3068\u3044\u3046\u73fe\u8c61\u304c\u3001\u306f\u3063\u304d\u308a\u3068\u6bdb\u9aea\u306e\u4e2d\u306b\u8a18\u9332\u3055\u308c\u3066\u3044\u305f\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u7814\u7a76\u306f\u3001\u767d\u9aea\u304c\u5358\u306a\u308b\u52a0\u9f62\u306e\u7d50\u679c\u3067\u306f\u306a\u304f\u3001\u300c\u8eab\u4f53\u3068\u5fc3\u306e\u72b6\u614b\u3092\u53cd\u6620\u3059\u308b\u30d0\u30a4\u30aa\u30ed\u30b0\uff08\u751f\u4f53\u8a18\u9332\uff09\u300d\u3067\u3042\u308b\u3053\u3068\u3092\u8a3c\u660e\u3057\u307e\u3057\u305f\u3002\u9aea\u306f\u9759\u304b\u306b\u3001\u3051\u308c\u3069\u3082\u6b63\u78ba\u306b\u3001\u79c1\u305f\u3061\u306e\u751f\u304d\u65b9\u3084\u611f\u60c5\u306e\u8ecc\u8de1\u3092\u8a18\u9332\u3057\u3066\u3044\u305f\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7b2c\u516d\u7ae0\uff1a\u690d\u7269\u3068\u5206\u5b50\u306e\u529b\u3067\u8272\u3092\u53d6\u308a\u623b\u3059\u2014\u2014\u767d\u9aea\u6cbb\u7642\u306e\u65b0\u3057\u3044\u5730\u5e73<\/p>\n\n\n\n<p>\u767d\u9aea\u3092\u300c\u4eba\u751f\u306e\u8a3c\u300d\u3068\u3057\u3066\u53d7\u3051\u5165\u308c\u308b\u4eba\u3082\u3044\u308c\u3070\u3001\u300c\u82e5\u3055\u306e\u8c61\u5fb4\u300d\u3068\u3057\u3066\u306e\u9ed2\u9aea\u3092\u53d6\u308a\u623b\u3057\u305f\u3044\u3068\u9858\u3046\u4eba\u3082\u3044\u307e\u3059\u3002\u305d\u3046\u3057\u305f\u9858\u3044\u306b\u5fdc\u3048\u308b\u5f62\u3067\u3001\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u306f\u767d\u9aea\u306e\u9032\u884c\u3092\u6291\u3048\u305f\u308a\u3001\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u9006\u8ee2\u3055\u305b\u308b\u305f\u3081\u306e\u300c\u5206\u5b50\u30ec\u30d9\u30eb\u306e\u6cbb\u7642\u6cd5\u300d\u306b\u6ce8\u76ee\u304c\u96c6\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4e2d\u3067\u3082\u7279\u306b\u6709\u671b\u3068\u3055\u308c\u3066\u3044\u308b\u306e\u304c\u3001\u690d\u7269\u7531\u6765\u306e\u5316\u5b66\u6210\u5206\u2015\u2015\u3044\u308f\u3086\u308b\u30d5\u30a3\u30c8\u30b1\u30df\u30ab\u30eb\uff08Phytochemicals\uff09\u2015\u2015\u306e\u529b\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u7ae0\u3067\u306f\u3001\u53e4\u6765\u304b\u3089\u4f1d\u7d71\u533b\u7642\u306b\u7528\u3044\u3089\u308c\u3066\u304d\u305f\u690d\u7269\u306e\u4e2d\u304b\u3089\u3001\u79d1\u5b66\u7684\u306b\u767d\u9aea\u306b\u5bfe\u3059\u308b\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3064\u3064\u3042\u308b\u3082\u306e\u3092\u3001\u5b9f\u9a13\u7d50\u679c\u3068\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u57fa\u3065\u3044\u3066\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">\u300c\u4e0d\u8001\u9577\u5bff\u306e\u8349\u300d\u2015\u2015\u4f55\u9996\u70cf\uff08\u304b\u3057\u3085\u3046\u3001Polygonum multiflorum\uff09<\/h3>\n\n\n\n<p>\u4e2d\u56fd\u306e\u53e4\u5178\u533b\u5b66\u66f8\u300e\u672c\u8349\u7db1\u76ee\u300f\u306b\u3082\u767b\u5834\u3059\u308b\u4f1d\u8aac\u7684\u306a\u85ac\u8349\u300c\u4f55\u9996\u70cf\uff08\u30ab\u30b7\u30e5\u30a6\uff09\u300d\u306f\u3001\u6700\u3082\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u308b\u5929\u7136\u306e\u6297\u767d\u9aea\u6210\u5206\u306e\u3072\u3068\u3064\u3067\u3059\u3002\u3053\u306e\u690d\u7269\u306b\u542b\u307e\u308c\u308b\u4ee3\u8868\u7684\u306a\u6709\u52b9\u6210\u5206\u306f\u3001TSG\uff082,3,5,4\u2032-\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u30ad\u30b7\u30b9\u30c1\u30eb\u30d9\u30f3-2-O-\u03b2-D-\u30b0\u30eb\u30b3\u30b7\u30c9\uff09\u3068\u30a8\u30e2\u30b8\u30f3\uff08Emodin\uff09\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u52d5\u7269\u5b9f\u9a13\u306b\u304a\u3044\u3066\u306f\u3001\u3053\u308c\u3089\u306e\u6210\u5206\u3092\u7d4c\u53e3\u3042\u308b\u3044\u306f\u5916\u7528\u3067\u6295\u4e0e\u3057\u305f\u30de\u30a6\u30b9\u306e\u767d\u9aea\u304c\u9ed2\u304f\u623b\u308b\u73fe\u8c61\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002TSG\u306f\u8272\u7d20\u5f62\u6210\u3092\u53f8\u308b\u8ee2\u5199\u56e0\u5b50MITF\u306e\u767a\u73fe\u3092\u4fc3\u9032\u3057\u3001\u305d\u308c\u306b\u3088\u3063\u3066\u8272\u7d20\u9175\u7d20\u3067\u3042\u308b\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\uff08TYR\uff09\u3084TRP1\u306e\u767a\u73fe\u3082\u5897\u52a0\u3057\u307e\u3059\u3002\u30a8\u30e2\u30b8\u30f3\u306f\u6297\u9178\u5316\u4f5c\u7528\u3068SIRT1\/FOXO1\u7d4c\u8def\u306e\u6d3b\u6027\u5316\u3092\u901a\u3058\u3066\u7d30\u80de\u306e\u8001\u5316\u3092\u6291\u5236\u3057\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u518d\u6d3b\u6027\u5316\u3092\u52a9\u3051\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u6ce8\u610f\u3059\u3079\u304d\u306f\u3001\u4f55\u9996\u70cf\u306e\u6210\u5206\u306f\u809d\u6bd2\u6027\uff08\u809d\u81d3\u3078\u306e\u5f71\u97ff\uff09\u304c\u3042\u308b\u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u3001\u9ad8\u7528\u91cf\u3067\u306e\u9577\u671f\u4f7f\u7528\u306f\u614e\u91cd\u306b\u6271\u3046\u3079\u304d\u3068\u3044\u3046\u70b9\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">\u7802\u6f20\u306e\u690d\u7269\u3001\u30a8\u30ea\u30aa\u30c7\u30a3\u30af\u30c1\u30aa\u30f3\uff08Eriodictyon angustifolium\uff09\u306e\u77e5\u6075<\/h3>\n\n\n\n<p>\u5317\u30a2\u30e1\u30ea\u30ab\u306e\u4e7e\u71e5\u5730\u5e2f\u306b\u81ea\u751f\u3059\u308b\u30a8\u30ea\u30aa\u30c7\u30a3\u30af\u30c1\u30aa\u30f3\u5c5e\u306e\u690d\u7269\u304b\u3089\u62bd\u51fa\u3055\u308c\u305f\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9\u985e\u3082\u307e\u305f\u3001\u8fd1\u5e74\u6ce8\u76ee\u3055\u308c\u308b\u6297\u767d\u9aea\u5019\u88dc\u3067\u3059\u3002\u4e2d\u3067\u3082\u3001\u30eb\u30c6\u30aa\u30ea\u30f3\uff08Luteolin\uff09\u3001\u30b9\u30c6\u30eb\u30d3\u30f3\uff08Sterubin\uff09\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30b2\u30f3\u30af\u30ef\u30cb\u30f3\uff08Hydroxygenkwanin\uff09\u3068\u3044\u3063\u305f\u6210\u5206\u306f\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u518d\u6d3b\u6027\u5316\u306b\u5bc4\u4e0e\u3059\u308b\u8907\u6570\u306e\u7d4c\u8def\u306b\u4f5c\u7528\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3068\u3048\u3070\u3001\u03b2-\u30ab\u30c6\u30cb\u30f3\u7d4c\u8def\uff08\u6bdb\u5305\u5e79\u7d30\u80de\u306e\u7dad\u6301\u306b\u91cd\u8981\uff09\u3084\u3001MAPK\uff08Mitogen-Activated Protein Kinase\uff09\u7d4c\u8def\u3092\u6d3b\u6027\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u8272\u7d20\u7d30\u80de\u306e\u5206\u5316\u3068\u30e1\u30e9\u30cb\u30f3\u5408\u6210\u3092\u5f8c\u62bc\u3057\u3057\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u3053\u308c\u3089\u306e\u6210\u5206\u306fDNA\u306e\u9178\u5316\u7684\u640d\u50b7\u3092\u9632\u304e\u3001\u8001\u5316\u6027\u5909\u5316\u304b\u3089\u7d30\u80de\u3092\u5b88\u308b\u3053\u3068\u3082\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30de\u30a6\u30b9\u5b9f\u9a13\u3067\u306f\u3001\u653e\u5c04\u7dda\u3084\u795e\u7d4c\u6bd2\u306b\u3088\u3063\u3066\u8a98\u767a\u3055\u308c\u305f\u767d\u9aea\u3092\u3001\u3053\u308c\u3089\u306e\u690d\u7269\u6210\u5206\u3092\u5857\u5e03\u3059\u308b\u3053\u3068\u3067\u9855\u8457\u306b\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3001\u4eba\u9593\u306e\u5c0f\u898f\u6a21\u306a\u81e8\u5e8a\u8a66\u9a13\u3067\u3082\u80af\u5b9a\u7684\u306a\u7d50\u679c\u304c\u5f97\u3089\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">\u4ed6\u306b\u3082\u5e83\u304c\u308b\u81ea\u7136\u306e\u30ec\u30d1\u30fc\u30c8\u30ea\u30fc<\/h3>\n\n\n\n<p>\u52a0\u3048\u3066\u3001\u30a2\u30b8\u30a2\u3067\u89aa\u3057\u307e\u308c\u3066\u3044\u308b\u5c0f\u8c46\uff08\u30a2\u30ba\u30ad\uff1aVigna angularis\uff09\u306b\u306f\u3001MITF\u3092PKA\uff08Protein Kinase A\uff09\u7d4c\u8def\u3092\u4ecb\u3057\u3066\u6d3b\u6027\u5316\u3059\u308b\u52b9\u679c\u304c\u3042\u308a\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u6d3b\u6027\u518d\u751f\u3092\u52a9\u3051\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u9ed2\u8336\uff08Fuzhuan Brick Tea\uff09\u306fNRF2\uff08Nuclear Factor Erythroid 2-Related Factor 2\uff09\u3068\u3044\u3046\u6297\u9178\u5316\u8ee2\u5199\u56e0\u5b50\u3092\u6d3b\u6027\u5316\u3057\u3001\u9aea\u306e\u4e2d\u306e\u6297\u9178\u5316\u9175\u7d20\u306e\u767a\u73fe\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u6bdb\u5305\u5185\u306e\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u8efd\u6e1b\u3057\u3001\u767d\u9aea\u5316\u3092\u4e88\u9632\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5357\u65b9\u7cfb\u690d\u7269\u4e94\u8449\u53c2\uff08Gynostemma pentaphyllum\uff09\u3084\u3001\u71b1\u5e2f\u690d\u7269\u7531\u6765\u306e\u8272\u7d20\u30d3\u30ad\u30b7\u30f3\uff08Bixin\uff1aBixa orellana\u7531\u6765\uff09\u3082\u540c\u69d8\u306bNRF2\u7d4c\u8def\u3092\u901a\u3058\u3066\u6297\u9178\u5316\u4f5c\u7528\u3092\u767a\u63ee\u3057\u3001\u7d2b\u5916\u7dda\u306a\u3069\u306b\u3088\u308b\u767d\u9aea\u8a98\u5c0e\u3092\u6291\u5236\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u30a6\u30f3\u30ab\u30ea\u30a2\u5c5e\uff08Uncaria spp.\uff09\u306b\u542b\u307e\u308c\u308b\u30ea\u30f3\u30b3\u30d5\u30a3\u30ea\u30f3\uff08Rhynchophylline\uff09\u306f\u3001\u524d\u7ae0\u3067\u8aac\u660e\u3057\u305f\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u7d4c\u8def\u306e\u4e00\u3064\u3067\u3042\u308b\u03b22\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d7\u5bb9\u4f53\uff08\u03b22AR\uff09\u3092\u963b\u5bb3\u3057\u3001MSC\u306e\u67af\u6e07\u3092\u9632\u3050\u4f5c\u7528\u304c\u3042\u308b\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">\u79d1\u5b66\u7684\u306b\u898b\u308b\u300c\u81ea\u7136\u300d\u306e\u529b<\/h3>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u690d\u7269\u6210\u5206\u306f\u5358\u306a\u308b\u6c11\u9593\u7642\u6cd5\u306e\u5ef6\u9577\u3067\u306f\u306a\u304f\u3001\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u4f5c\u7528\u6a5f\u5e8f\u304c\u89e3\u660e\u3055\u308c\u3064\u3064\u3042\u308b\u300c\u79d1\u5b66\u7684\u306b\u6709\u671b\u306a\u5019\u88dc\u300d\u306a\u306e\u3067\u3059\u3002\u5171\u901a\u3059\u308b\u30c6\u30fc\u30de\u306f\u3001\u2460\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306e\u8efd\u6e1b\u3001\u2461\u8272\u7d20\u5f62\u6210\u907a\u4f1d\u5b50\u306e\u6d3b\u6027\u5316\u3001\u2462\u5e79\u7d30\u80de\u306e\u4fdd\u8b77\u3068\u6d3b\u6027\u5316\u3001\u3068\u3044\u30463\u672c\u67f1\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u52b9\u679c\u306e\u591a\u304f\u306f\u307e\u3060\u52d5\u7269\u5b9f\u9a13\u304b\u3001\u5c0f\u898f\u6a21\u306a\u4e88\u5099\u7684\u81e8\u5e8a\u8a66\u9a13\u306b\u3068\u3069\u307e\u3063\u3066\u304a\u308a\u3001\u30d2\u30c8\u3078\u306e\u672c\u683c\u7684\u306a\u5fdc\u7528\u306b\u306f\u3055\u3089\u306a\u308b\u7814\u7a76\u3068\u5b89\u5168\u6027\u691c\u8a3c\u304c\u5fc5\u8981\u3067\u3059\u3002\u3068\u306f\u3044\u3048\u3001\u8001\u5316\u306b\u5bfe\u3059\u308b\u81ea\u7136\u306e\u30ec\u30b8\u30ea\u30a8\u30f3\u30b9\uff08\u56de\u5fa9\u529b\uff09\u3092\u6d3b\u304b\u3059\u3068\u3044\u3046\u89b3\u70b9\u304b\u3089\u3082\u3001\u3053\u306e\u5206\u91ce\u306f\u307e\u3059\u307e\u3059\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u7b2c\u4e03\u7ae0\uff1a\u518d\u751f\u3078\u306e\u53ef\u80fd\u6027\u2014\u2014\u672a\u6765\u306e\u767d\u9aea\u5bfe\u7b56\u3068\u8001\u5316\u7814\u7a76\u306e\u5148\u306b<\/strong><\/h2>\n\n\n\n<p>\u767d\u9aea\u7814\u7a76\u306e\u6700\u524d\u7dda\u306f\u3001\u5358\u306a\u308b\u300c\u7f8e\u5bb9\u306e\u554f\u984c\u300d\u3092\u8d85\u3048\u3066\u3001\u300c\u8001\u5316\u3068\u3044\u3046\u73fe\u8c61\u306e\u6838\u5fc3\u300d\u306b\u8feb\u308d\u3046\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u306a\u305c\u306a\u3089\u3001\u767d\u9aea\u3068\u306f\u5e79\u7d30\u80de\u306e\u67af\u6e07\u3001\u9178\u5316\u7684\u640d\u50b7\u3001\u907a\u4f1d\u5b50\u5236\u5fa1\u306e\u4e71\u308c\u2015\u2015\u3059\u306a\u308f\u3061\u8001\u5316\u305d\u306e\u3082\u306e\u306e\u7e2e\u56f3\u3060\u304b\u3089\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u5c06\u6765\u7684\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u6280\u8853\u304c\u81e8\u5e8a\u5fdc\u7528\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5e79\u7d30\u80de\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/minimally-invasive-hair-transplant\/\">\u79fb\u690d<\/a>\uff1a\u3059\u3067\u306b\u767d\u6591\uff08\u3073\u306f\u304f\u3001Vitiligo\uff09\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u5e79\u7d30\u80de\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/minimally-invasive-hair-transplant\/\">\u79fb\u690d<\/a>\u304c\u8a66\u307f\u3089\u308c\u3066\u3044\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u907a\u4f1d\u5b50\u5236\u5fa1\u85ac\uff1aMITF\u3084IRF4\u3001TYR\u306a\u3069\u306e\u767a\u73fe\u3092\u76f4\u63a5\u8abf\u6574\u3059\u308b\u85ac\u5264\u306e\u958b\u767a\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<br><\/li>\n\n\n\n<li>\u30b9\u30c8\u30ec\u30b9\u5fdc\u7b54\u963b\u5bb3\u85ac\uff1a\u03b22AR\u3092\u30d6\u30ed\u30c3\u30af\u3059\u308b\u5206\u5b50\u3092\u4f7f\u3044\u3001MSC\u306e\u6d88\u8017\u3092\u6291\u3048\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3002<br><\/li>\n\n\n\n<li>\u6bdb\u5305\u5358\u4f4d\u306e\u500b\u5225\u8a3a\u65ad\uff1a\u4e00\u4eba\u3072\u3068\u308a\u306e\u6bdb\u5305\u306e\u72b6\u614b\u3092\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3057\u3001\u7cbe\u5bc6\u306a\u500b\u5225\u6cbb\u7642\u306b\u7e4b\u3052\u308b\u30de\u30a4\u30af\u30ed\u30d0\u30a4\u30aa\u30d7\u30b7\u30fc\u6280\u8853\u3002<br><\/li>\n<\/ul>\n\n\n\n<p>\u767d\u9aea\u306f\u3001\u9aea\u306e\u8272\u306e\u554f\u984c\u306b\u3068\u3069\u307e\u308a\u307e\u305b\u3093\u3002\u305d\u308c\u306f\u300c\u5e79\u7d30\u80de\u306e\u5bff\u547d\u300d\u300c\u9178\u5316\u30c0\u30e1\u30fc\u30b8\u306e\u4fee\u5fa9\u529b\u300d\u300c\u7cbe\u795e\u7684\u30b9\u30c8\u30ec\u30b9\u3068\u8eab\u4f53\u306e\u95a2\u4fc2\u6027\u300d\u3068\u3044\u3063\u305f\u3001\u4eba\u9593\u306e\u6839\u6e90\u7684\u306a\u5065\u5eb7\u3068\u8001\u5316\u306e\u554f\u984c\u306b\u76f4\u7d50\u3057\u3066\u3044\u307e\u3059\u3002\u9aea\u306f\u3001\u76ee\u306b\u898b\u3048\u308b\u201c\u8001\u5316\u306e\u30ab\u30ca\u30ea\u30a2\u201d\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u6700\u7d42\u7ae0\uff1a\u3042\u306a\u305f\u306e\u9aea\u304c\u3001\u3042\u306a\u305f\u306e\u4eba\u751f\u3092\u8a9e\u308b<\/strong><\/h2>\n\n\n\n<p>\u8ab0\u3082\u304c\u5e74\u3092\u3068\u308a\u307e\u3059\u3002\u767d\u9aea\u3082\u307e\u305f\u3001\u305d\u306e\u4e00\u90e8\u3068\u3057\u3066\u8a2a\u308c\u308b\u73fe\u8c61\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u305d\u306e\u4e00\u672c\u4e00\u672c\u306b\u306f\u3001\u5358\u306a\u308b\u8272\u306e\u5909\u5316\u3067\u306f\u306a\u304f\u3001\u3042\u306a\u305f\u81ea\u8eab\u306e\u751f\u304d\u65b9\u3084\u74b0\u5883\u3001\u5fc3\u306e\u63fa\u308c\u307e\u3067\u3082\u304c\u8a18\u9332\u3055\u308c\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4eca\u65e5\u3001\u93e1\u306e\u4e2d\u306b\u65b0\u305f\u306a\u767d\u9aea\u3092\u898b\u3064\u3051\u305f\u3068\u304d\u3001\u305d\u308c\u306f\u8001\u3044\u306e\u8c61\u5fb4\u3067\u306f\u306a\u304f\u3001\u3042\u306a\u305f\u306e\u4f53\u304c\u767a\u3057\u3066\u3044\u308b\u5fae\u7d30\u306a\u30b7\u30b0\u30ca\u30eb\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u4f11\u606f\u304c\u8db3\u308a\u3066\u3044\u306a\u3044\u306e\u304b\u3001\u6804\u990a\u304c\u504f\u3063\u3066\u3044\u306a\u3044\u304b\u3001\u5fc3\u304c\u75b2\u308c\u3066\u3044\u306a\u3044\u304b\u2015\u2015\u9aea\u306f\u3001\u305d\u3093\u306a\u554f\u3044\u304b\u3051\u3092\u9759\u304b\u306b\u6295\u3052\u304b\u3051\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u5c0f\u3055\u306a\u300c\u6bdb\u306e\u5b87\u5b99\u300d\u3092\u898b\u3064\u3081\u308b\u3053\u3068\u306f\u3001\u8001\u5316\u3068\u3044\u3046\u73fe\u8c61\u306b\u5bfe\u3057\u3066\u3001\u3042\u305f\u305f\u304b\u304f\u3001\u304b\u3064\u79d1\u5b66\u7684\u306b\u5411\u304d\u5408\u3046\u7b2c\u4e00\u6b69\u306b\u306a\u308b\u3067\u3057\u3087\u3046\u3002\u305d\u3057\u3066\u305d\u306e\u5148\u306b\u306f\u3001\u518d\u751f\u3001\u56de\u5fa9\u3001\u305d\u3057\u3066\u65b0\u305f\u306a\u6cbb\u7642\u306e\u53ef\u80fd\u6027\u304c\u5e83\u304c\u3063\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u5f15\u7528\u6587\u732e<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/doi.org\/10.1111\/j.1365-2133.2011.10625.x\">Choi, H. I., \u307b\u304b. \u300cHair Greying Is Associated with Active Hair Growth: Hair Greying and Active Hair Growth\u300d. <em>British Journal of Dermatology<\/em>, vol. 165, no. 6, 2011\u5e7412\u6708, pp. 1183\u201389. <em>DOI.org (Crossref)<\/em>, https:\/\/doi.org\/10.1111\/j.1365-2133.2011.10625.x.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.3390\/app14177450\">Boo, Yong Chool. \u300cIntrinsic and Extrinsic Factors Associated with Hair Graying (Canities) and Therapeutic Potential of Plant Extracts and Phytochemicals\u300d. <em>Applied Sciences<\/em>, vol. 14, no. 17, 2024\u5e748\u6708, p. 7450. <em>DOI.org (Crossref)<\/em>, https:\/\/doi.org\/10.3390\/app14177450.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.arr.2023.101977\">Wang, Sifan, \u307b\u304b. \u300cGenetics of Hair Graying with Age\u300d. <em>Ageing Research Reviews<\/em>, vol. 89, 2023\u5e748\u6708, p. 101977. <em>DOI.org (Crossref)<\/em>, https:\/\/doi.org\/10.1016\/j.arr.2023.101977.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.7554\/eLife.67437\">Rosenberg, Ayelet M., \u307b\u304b. \u300cQuantitative Mapping of Human Hair Greying and Reversal in Relation to Life Stress\u300d. <em>eLife<\/em>, vol. 10, 2021\u5e746\u6708, p. e67437. <em>DOI.org (Crossref)<\/em>, https:\/\/doi.org\/10.7554\/eLife.67437.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1111\/brv.12648\">O\u2019Sullivan, James D. B., \u307b\u304b. \u300cThe Biology of Human Hair Greying\u300d. <em>Biological Reviews<\/em>, vol. 96, no. 1, 2021\u5e742\u6708, pp. 107\u201328. <em>DOI.org (Crossref)<\/em>, https:\/\/doi.org\/10.1111\/brv.12648.<\/a><\/li>\n<\/ul>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-1-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u7b2c\u4e00\u7ae0\uff1a\u767d\u9aea\u306f\u8001\u5316\u306e\u300c\u8a3c\u62e0\u54c1\u300d\u304b\u3001\u305d\u308c\u3068\u3082\u751f\u547d\u306e\u8db3\u8de1\u304b \u4eba\u751f\u306b\u304a\u3044\u3066\u3001\u93e1\u306b\u6620\u308b\u81ea\u5206\u306e\u59ff\u304c\u5909\u5316\u3057\u3066\u3044\u304f\u3053\u3068\u307b\u3069\u3001\u6642\u9593\u306e\u6d41\u308c\u3092\u5b9f\u611f\u3055\u305b\u308b\u77ac\u9593\u306f\u306a\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3042\u308b\u671d\u3075\u3068\u3001\u9aea\u306e\u4e2d\u306b\u3072\u3068\u7b4b\u306e\u767d\u3092\u898b\u3064\u3051\u305f\u3068\u304d\u3001\u591a\u304f\u306e\u4eba\u304c\u300c\u8001\u3044\u300d\u3068\u3044\u3046\u8a00\u8449\u3092\u521d\u3081\u3066\u610f\u8b58\u3057\u307e\u3059\u3002\u767d\u9aea\u3001\u305d\u308c\u306f\u8ab0\u3082\u304c\u907f\u3051\u3089\u308c\u306a\u3044\u52a0\u9f62\u306e\u8a3c\u3001\u305d\u3046\u4fe1\u3058\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002 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Follicle\uff09\u3068\u3044\u3046\u5c0f\u3055\u306a\u5668\u5b98\u306e\u4e2d\u3067\u4eca\u3082\u9032\u884c\u3059\u308b\u300c\u751f\u306e\u30d7\u30ed\u30bb\u30b9\u300d\u2015\u2015\u3059\u306a\u308f\u3061\u7d30\u80de\u6d3b\u52d5\u3001\u4ee3\u8b1d\u3001\u518d\u751f\u3001\u305d\u3057\u3066\u74b0\u5883\u3068\u306e\u5bfe\u8a71\u2015\u2015\u305d\u306e\u6700\u524d\u7dda\u306e\u8a18\u9332\u306a\u306e\u3067\u3059\u3002 \u3053\u306e\u7269\u8a9e\u306f\u3001\u7d30\u80de\u306e\u3055\u3055\u3084\u304d\u306b\u8033\u3092\u50be\u3051\u308b\u3053\u3068\u304b\u3089\u59cb\u307e\u308a\u307e\u3059\u3002\u79d1\u5b66\u8005\u305f\u3061\u306f\u9855\u5fae\u93e1\u3092\u8997\u304d\u8fbc\u307f\u3001DNA\u3084\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u767a\u73fe\u3092\u89e3\u6790\u3057\u3001\u767d\u9aea\u3068\u3044\u3046\u8b0e\u3092\u89e3\u304d\u660e\u304b\u305d\u3046\u3068\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u672c\u7a3f\u3067\u306f\u305d\u306e\u7814\u7a76\u6210\u679c\u3092\u3001\u7269\u8a9e\u3068\u3057\u3066\u7d21\u304e\u306a\u304c\u3089\u4e01\u5be7\u306b\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u5c02\u9580\u5bb6\u306e\u65b9\u306b\u306f\u79d1\u5b66\u7684\u77e5\u898b\u306e\u6df1\u307f\u3092\u3001\u4e00\u822c\u306e\u8aad\u8005\u306b\u306f\u81ea\u5206\u306e\u9aea\u306b\u5bbf\u308b\u300c\u751f\u304d\u305f\u6b74\u53f2\u300d\u306e\u4e00\u7aef\u3092\u611f\u3058\u3066\u3044\u305f\u3060\u3051\u308b\u3088\u3046\u3001\u3067\u304d\u308b\u304b\u304e\u308a\u6a4b\u6e21\u3057\u3092\u8a66\u307f\u307e\u3059\u3002 \u7b2c\u4e8c\u7ae0\uff1a\u767d\u9aea\u306f\u3080\u3057\u308d\u300c\u6d3b\u767a\u306a\u9aea\u300d\u3060\u3063\u305f\u2014\u2014\u6210\u9577\u3068\u8001\u5316\u306e\u76ae\u8089\u306a\u95a2\u4fc2 \u300c\u767d\u9aea\uff1d\u8001\u5316\u3057\u305f\u5f31\u3044\u9aea\u300d\u3068\u3044\u3046\u5148\u5165\u89b3\u304c\u3001\u6700\u65b0\u306e\u7814\u7a76\u306b\u3088\u3063\u3066\u8986\u3055\u308c\u3088\u3046\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u4eba\u7537\u6027\u306e\u982d\u76ae\u304b\u3089\u63a1\u53d6\u3055\u308c\u305f\u9aea\u306e\u6bdb\u3092\u8abf\u3079\u305f\u3068\u3053\u308d\u3001\u767d\u9aea\u306f\u9ed2\u9aea\u3088\u308a\u3082\u300c\u592a\u304f\u300d\u300c\u4f38\u3073\u308b\u901f\u5ea6\u304c\u65e9\u3044\u300d\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u305f\u306e\u3067\u3059\u3002 \u3053\u306e\u89b3\u5bdf\u7d50\u679c\u3092\u88cf\u3065\u3051\u308b\u305f\u3081\u3001\u6bdb\u6839\u304b\u3089\u63a1\u53d6\u3057\u305fRNA\u3092\u4f7f\u3063\u3066\u7db2\u7f85\u7684\u306a\u907a\u4f1d\u5b50\u767a\u73fe\u89e3\u6790\uff08\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u89e3\u6790\uff09\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002\u3059\u308b\u3068\u3001\u767d\u9aea\u306e\u6bdb\u5305\u3067\u306f\u30b1\u30e9\u30c1\u30f3\uff08KRT\uff09\u304a\u3088\u3073\u30b1\u30e9\u30c1\u30f3\u95a2\u9023\u30bf\u30f3\u30d1\u30af\u8cea\uff08KRTAP\uff09\u3092\u30b3\u30fc\u30c9\u3059\u308b\u907a\u4f1d\u5b50\u304c\u6709\u610f\u306b\u4e0a\u6607\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u30b1\u30e9\u30c1\u30f3\u3068\u306f\u3001\u9aea\u306e\u69cb\u9020\u305d\u306e\u3082\u306e\u3092\u5f62\u4f5c\u308b\u4e3b\u8981\u306a\u7e4a\u7dad\u72b6\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u3002KRT16\uff0812\u500d\u5897\uff09\u3001KRT6C\uff0810.4\u500d\u5897\uff09\u3001KRT83\uff087.7\u500d\u5897\uff09\u3068\u3044\u3063\u305f\u907a\u4f1d\u5b50\u306f\u3001\u9aea\u306e\u5f3e\u529b\u6027\u3084\u5f37\u5ea6\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u5358\u306b\u69cb\u9020\u304c\u5909\u308f\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u7269\u7406\u7684\u306a\u7279\u6027\u306b\u3082\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002 \u3055\u3089\u306b\u3001\u6210\u9577\u56e0\u5b50\u306e\u767a\u73fe\u3082\u5909\u5316\u3057\u3066\u3044\u307e\u3057\u305f\u3002FGF5\uff08Fibroblast Growth Factor 5\uff09\u306f\u3001\u9aea\u306e\u6210\u9577\u671f\u3092\u7d42\u4e86\u3055\u305b\u308b\u30b7\u30b0\u30ca\u30eb\u3092\u51fa\u3059\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u304c\u3001\u767d\u9aea\u3067\u306f\u3053\u306e\u56e0\u5b50\u306e\u767a\u73fe\u304c\u6e1b\u5c11\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u4e00\u65b9\u3001\u6210\u9577\u4fc3\u9032\u56e0\u5b50\u3067\u3042\u308bFGF7\u306f\u5897\u52a0\u3057\u3066\u304a\u308a\u3001\u767d\u9aea\u306e\u6bdb\u5305\u304c\u300c\u6210\u9577\u30e2\u30fc\u30c9\u300d\u306b\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002 \u3064\u307e\u308a\u3001\u767d\u9aea\u306f\u751f\u7406\u5b66\u7684\u306b\u300c\u8870\u3048\u305f\u9aea\u300d\u3067\u306f\u306a\u304f\u3001\u3080\u3057\u308d\u300c\u6d3b\u767a\u306b\u6210\u9577\u3057\u3066\u3044\u308b\u9aea\u300d\u3060\u3063\u305f\u306e\u3067\u3059\u3002\u3053\u306e\u9006\u8aac\u7684\u306a\u767a\u898b\u306f\u3001\u300c\u9aea\u304c\u6d3b\u767a\u306b\u6210\u9577\u3057\u3059\u304e\u308b\u3053\u3068\u3067\u3001\u8272\u7d20\u7d30\u80de\u306b\u904e\u5270\u306a\u8ca0\u8377\u304c\u304b\u304b\u308a\u3001\u30e1\u30e9\u30cb\u30f3\u306e\u4f9b\u7d66\u304c\u8ffd\u3044\u3064\u304b\u306a\u304f\u306a\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u300d\u3068\u3044\u3046\u65b0\u305f\u306a\u4eee\u8aac\u3092\u5c0e\u304d\u51fa\u3057\u307e\u3059\u3002 \u7b2c\u4e09\u7ae0\uff1a\u8272\u3092\u3064\u304b\u3055\u3069\u308b\u7d30\u80de\u306e\u4e00\u751f\u2014\u2014\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u8a95\u751f\u3068\u6b7b \u3067\u306f\u3001\u306a\u305c\u6d3b\u767a\u306b\u6210\u9577\u3059\u308b\u767d\u9aea\u306b\u3060\u3051\u3001\u8272\u7d20\u304c\u5931\u308f\u308c\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u305d\u306e\u9375\u3092\u63e1\u308b\u306e\u304c\u3001\u6bdb\u5305\u5185\u306b\u5b58\u5728\u3059\u308b\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\uff08Melanocyte\uff09\u3067\u3059\u3002\u3053\u306e\u8272\u7d20\u7d30\u80de\u306f\u3001\u9ed2\u3084\u8336\u8272\u306e\u8272\u7d20\u3067\u3042\u308b\u30e1\u30e9\u30cb\u30f3\u3092\u5408\u6210\u3057\u3001\u305d\u308c\u3092\u9aea\u306e\u6bdb\u306e\u89d2\u5316\u7d30\u80de\u306b\u4f9b\u7d66\u3059\u308b\u3053\u3068\u3067\u3001\u9aea\u306e\u8272\u3092\u6c7a\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002 \u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u81ea\u4f53\u306f\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u5e79\u7d30\u80de\uff08Melanocyte Stem Cell, MSC\uff09\u304b\u3089\u4f9b\u7d66\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u5e79\u7d30\u80de\u306f\u6bdb\u5305\u306e\u300c\u30d0\u30eb\u30b8\u9818\u57df\u300d\u3068\u547c\u3070\u308c\u308b\u5834\u6240\u306b\u6f5c\u3093\u3067\u304a\u308a\u3001\u9aea\u306e\u6210\u9577\u3068\u3068\u3082\u306b\u5206\u5316\u3057\u3066\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u3068\u306a\u308a\u3001\u8272\u7d20\u3092\u4f5c\u308a\u51fa\u3059\u306e\u3067\u3059\u3002 \u3057\u304b\u3057\u3001\u5fc3\u7406\u7684\u30b9\u30c8\u30ec\u30b9\u3084\u9178\u5316\u30b9\u30c8\u30ec\u30b9\uff08\u6b21\u7ae0\u3067\u8a73\u8ff0\uff09\u306a\u3069\u306b\u3088\u308a\u3001MSC\u304c\u904e\u5270\u306b\u52d5\u54e1\u3055\u308c\u305f\u308a\u3001\u8aa4\u3063\u305f\u30bf\u30a4\u30df\u30f3\u30b0\u3067\u5206\u5316\u3057\u3066\u3057\u307e\u3046\u3068\u3001\u305d\u306e\u4f9b\u7d66\u304c\u67af\u6e07\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\uff08\u30b9\u30c8\u30ec\u30b9\u30db\u30eb\u30e2\u30f3\u306e\u4e00\u7a2e\uff09\u306f\u03b22\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d7\u5bb9\u4f53\uff08\u03b22AR\uff09\u3092\u4ecb\u3057\u3066MSC\u306b\u4f5c\u7528\u3057\u3001\u6c38\u4e45\u7684\u306a\u67af\u6e07\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u30de\u30a6\u30b9\u5b9f\u9a13\u3067\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u307e\u305f\u3001MITF\uff08Microphthalmia-associated Transcription Factor\uff09\u3068\u3044\u3046\u8ee2\u5199\u56e0\u5b50\u306f\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306e\u751f\u5b58\u3068\u6a5f\u80fd\u7dad\u6301\u306b\u5fc5\u8981\u4e0d\u53ef\u6b20\u3067\u3042\u308a\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u7570\u5e38\u3082\u767d\u9aea\u306e\u4e00\u56e0\u3068\u306a\u308a\u307e\u3059\u3002MITF\u306f\u8272\u7d20\u751f\u6210\u9175\u7d20\u3067\u3042\u308b\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\uff08TYR\uff09\u3084TRP1\u306a\u3069\u306e\u767a\u73fe\u3092\u8abf\u6574\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u7fa4\u304c\u540c\u6642\u306b\u6c88\u9ed9\u3059\u308b\u3053\u3068\u3067\u3001\u30e1\u30e9\u30cb\u30f3\u5408\u6210\u304c\u505c\u6b62\u3057\u3066\u3057\u307e\u3044\u307e\u3059\u3002 \u3053\u306e\u3088\u3046\u306b\u3001\u767d\u9aea\u306f\u5358\u306b\u300c\u8272\u304c\u629c\u3051\u305f\u9aea\u300d\u3067\u306f\u306a\u304f\u3001\u300c\u5e79\u7d30\u80de\u4f9b\u7d66\u306e\u7834\u7dbb\u300d\u3068\u300c\u8ee2\u5199\u5236\u5fa1\u306e\u7570\u5e38\u300d\u304c\u91cd\u306a\u3063\u305f\u3001\u7cbe\u7dfb\u306a\u751f\u7269\u5b66\u7684\u30d7\u30ed\u30bb\u30b9\u306e\u672b\u306b\u73fe\u308c\u308b\u73fe\u8c61\u306a\u306e\u3067\u3059\u3002 \u7b2c\u56db\u7ae0\uff1a\u898b\u3048\u306a\u3044\u6575\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u2014\u2014\u9aea\u306e\u4e2d\u3067\u8d77\u304d\u3066\u3044\u308b\u708e\u75c7\u3068\u640d\u50b7 \u751f\u7269\u306b\u3068\u3063\u3066\u9178\u7d20\u306f\u4e0d\u53ef\u6b20\u306a\u5b58\u5728\u3067\u3059\u304c\u3001\u305d\u306e\u4ee3\u8b1d\u904e\u7a0b\u3067\u751f\u3058\u308b\u526f\u7523\u7269\u2015\u2015\u6d3b\u6027\u9178\u7d20\u7a2e\uff08Reactive Oxygen Species, ROS\uff09\u306f\u3001\u7d30\u80de\u306b\u6df1\u523b\u306a\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u308b\u5203\u3068\u3082\u306a\u308a\u307e\u3059\u3002\u7279\u306b\u6bdb\u5305\u5185\u306e\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u306f\u3001\u30e1\u30e9\u30cb\u30f3\u5408\u6210\u306e\u904e\u7a0b\u305d\u306e\u3082\u306e\u304c\u9ad8\u3044\u9178\u5316\u8ca0\u8377\u3092\u751f\u307f\u51fa\u3059\u305f\u3081\u3001\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u306b\u975e\u5e38\u306b\u5f31\u3044\u7d30\u80de\u306a\u306e\u3067\u3059\u3002 \u767d\u9aea\u306e\u6bdb\u5305\u3092\u9855\u5fae\u93e1\u3067\u89b3\u5bdf\u3059\u308b\u3068\u3001\u30e1\u30e9\u30ce\u30bd\u30fc\u30e0\uff08\u30e1\u30e9\u30cb\u30f3\u3092\u8caf\u8535\u3059\u308b\u7d30\u80de\u5c0f\u5668\u5b98\uff09\u304c\u8457\u3057\u304f\u6e1b\u5c11\u3057\u3066\u304a\u308a\u3001\u6b8b\u5b58\u3059\u308b\u3082\u306e\u3082\u69cb\u9020\u7684\u306b\u7834\u58ca\u3055\u308c\u3001\u7a7a\u80de\u5316\uff08\u30d0\u30ad\u30e5\u30aa\u30fc\u30eb\u5f62\u6210\uff09\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u306f\u3001ROS\u306e\u84c4\u7a4d\u306b\u3088\u3063\u3066\u7d30\u80de\u304c\u5185\u90e8\u304b\u3089\u300c\u7126\u3052\u308b\u3088\u3046\u306b\u300d\u7834\u58ca\u3055\u308c\u3066\u3044\u308b\u8a3c\u62e0\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002 \u3055\u3089\u306b\u3001ROS\u306e\u4e00\u7a2e\u3067\u3042\u308b\u904e\u9178\u5316\u6c34\u7d20\uff08H\u2082O\u2082\uff09\u306f\u3001\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u306e\u6d3b\u6027\u90e8\u4f4d\u3092\u9178\u5316\u3057\u3001\u9175\u7d20\u3092\u4e0d\u6d3b\u6027\u5316\u3055\u305b\u3066\u3057\u307e\u3046\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u901a\u5e38\u3067\u3042\u308c\u3070\u30ab\u30bf\u30e9\u30fc\u30bc\u3068\u3044\u3046\u9175\u7d20\u304cH\u2082O\u2082\u3092\u5206\u89e3\u3057\u3066\u304f\u308c\u307e\u3059\u304c\u3001\u767d\u9aea\u306e\u6bdb\u5305\u3067\u306f\u30ab\u30bf\u30e9\u30fc\u30bc\u306e\u767a\u73fe\u304c\u4f4e\u4e0b\u3057\u3066\u304a\u308a\u3001\u9632\u5fa1\u6a5f\u69cb\u304c\u7834\u7dbb\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002 \u3053\u306e\u3088\u3046\u306b\u3001\u767d\u9aea\u306f\u7d30\u80de\u6b7b\u306e\u75d5\u8de1\u3067\u3042\u308b\u3068\u540c\u6642\u306b\u3001\u300c\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3068\u3044\u3046\u708e\u300d\u306b\u3088\u3063\u3066\u713c\u304b\u308c\u305f\u751f\u547d\u306e\u8a18\u9332\u3067\u3082\u3042\u308b\u306e\u3067\u3059\u3002 \u7b2c\u4e94\u7ae0\uff1a\u9aea\u306f\u4eba\u751f\u3092\u8a18\u9332\u3059\u308b\u2014\u2014\u767d\u9aea\u3068\u30b9\u30c8\u30ec\u30b9\u3001\u305d\u3057\u3066\u518d\u751f\u306e\u7269\u8a9e \u9577\u3089\u304f\u3001\u767d\u9aea\u306f\u4e0d\u53ef\u9006\u7684\u306a\u5909\u5316\u3067\u3042\u308b\u3068\u4fe1\u3058\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u30012021\u5e74\u306b\u767a\u8868\u3055\u308c\u305f\u753b\u671f\u7684\u306a\u7814\u7a76\u306b\u3088\u3063\u3066\u3001\u300c\u767d\u9aea\u304c\u9ed2\u9aea\u3078\u623b\u308b\u300d\u3068\u3044\u3046\u73fe\u8c61\u304c\u79d1\u5b66\u7684\u306b\u89b3\u5bdf\u3055\u308c\u307e\u3057\u305f\u3002 \u3053\u306e\u7814\u7a76\u3067\u306f\u300114\u4eba\u306e\u88ab\u9a13\u8005\u304b\u3089\u5f97\u3089\u308c\u305f\u5408\u8a08397\u672c\u306e\u6bdb\u9aea\u3092\u9ad8\u89e3\u50cf\u5ea6\u3067\u30b9\u30ad\u30e3\u30f3\u3057\u3001\u6bdb\u5e79\uff08\u9aea\u306e\u30b7\u30e3\u30d5\u30c8\uff09\u306b\u6cbf\u3063\u3066\u8272\u7d20\u30d1\u30bf\u30fc\u30f3\u3092\u6642\u9593\u8ef8\u3068\u3057\u3066\u53ef\u8996\u5316\u3057\u307e\u3057\u305f\u3002\u4eba\u9593\u306e\u9aea\u306f\u7d041\u30f6\u6708\u306b1cm\u4f38\u3073\u308b\u305f\u3081\u3001\u8272\u7d20\u306e\u5909\u5316\u306f\u305d\u306e\u307e\u307e\u6642\u9593\u306e\u7d4c\u904e\u3092\u793a\u3059\u300c\u6bdb\u306e\u5e74\u8868\u300d\u3068\u306a\u308a\u307e\u3059\u3002 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\u4e2d\u56fd\u306e\u53e4\u5178\u533b\u5b66\u66f8\u300e\u672c\u8349\u7db1\u76ee\u300f\u306b\u3082\u767b\u5834\u3059\u308b\u4f1d\u8aac\u7684\u306a\u85ac\u8349\u300c\u4f55\u9996\u70cf\uff08\u30ab\u30b7\u30e5\u30a6\uff09\u300d\u306f\u3001\u6700\u3082\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u308b\u5929\u7136\u306e\u6297\u767d\u9aea\u6210\u5206\u306e\u3072\u3068\u3064\u3067\u3059\u3002\u3053\u306e\u690d\u7269\u306b\u542b\u307e\u308c\u308b\u4ee3\u8868\u7684\u306a\u6709\u52b9\u6210\u5206\u306f\u3001TSG\uff082,3,5,4\u2032-\u30c6\u30c8\u30e9\u30d2\u30c9\u30ed\u30ad\u30b7\u30b9\u30c1\u30eb\u30d9\u30f3-2-O-\u03b2-D-\u30b0\u30eb\u30b3\u30b7\u30c9\uff09\u3068\u30a8\u30e2\u30b8\u30f3\uff08Emodin\uff09\u3067\u3059\u3002 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\u305f\u3068\u3048\u3070\u3001\u03b2-\u30ab\u30c6\u30cb\u30f3\u7d4c\u8def\uff08\u6bdb\u5305\u5e79\u7d30\u80de\u306e\u7dad\u6301\u306b\u91cd\u8981\uff09\u3084\u3001MAPK\uff08Mitogen-Activated Protein Kinase\uff09\u7d4c\u8def\u3092\u6d3b\u6027\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u8272\u7d20\u7d30\u80de\u306e\u5206\u5316\u3068\u30e1\u30e9\u30cb\u30f3\u5408\u6210\u3092\u5f8c\u62bc\u3057\u3057\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u3053\u308c\u3089\u306e\u6210\u5206\u306fDNA\u306e\u9178\u5316\u7684\u640d\u50b7\u3092\u9632\u304e\u3001\u8001\u5316\u6027\u5909\u5316\u304b\u3089\u7d30\u80de\u3092\u5b88\u308b\u3053\u3068\u3082\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u30de\u30a6\u30b9\u5b9f\u9a13\u3067\u306f\u3001\u653e\u5c04\u7dda\u3084\u795e\u7d4c\u6bd2\u306b\u3088\u3063\u3066\u8a98\u767a\u3055\u308c\u305f\u767d\u9aea\u3092\u3001\u3053\u308c\u3089\u306e\u690d\u7269\u6210\u5206\u3092\u5857\u5e03\u3059\u308b\u3053\u3068\u3067\u9855\u8457\u306b\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3001\u4eba\u9593\u306e\u5c0f\u898f\u6a21\u306a\u81e8\u5e8a\u8a66\u9a13\u3067\u3082\u80af\u5b9a\u7684\u306a\u7d50\u679c\u304c\u5f97\u3089\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002 \u4ed6\u306b\u3082\u5e83\u304c\u308b\u81ea\u7136\u306e\u30ec\u30d1\u30fc\u30c8\u30ea\u30fc \u52a0\u3048\u3066\u3001\u30a2\u30b8\u30a2\u3067\u89aa\u3057\u307e\u308c\u3066\u3044\u308b\u5c0f\u8c46\uff08\u30a2\u30ba\u30ad\uff1aVigna angularis\uff09\u306b\u306f\u3001MITF\u3092PKA\uff08Protein Kinase 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