{"id":6838,"date":"2025-03-18T05:36:47","date_gmt":"2025-03-18T05:36:47","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/?p=6838"},"modified":"2025-04-04T00:50:32","modified_gmt":"2025-04-04T00:50:32","slug":"pepopumpkin","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/pepopumpkin\/","title":{"rendered":"\u8584\u6bdb\u306e\u539f\u56e0\u306f\u30db\u30eb\u30e2\u30f3\u3060\u3063\u305f\uff1f\u30ab\u30dc\u30c1\u30e3\u3067\u3075\u308f\u3075\u308f\u30b5\u30e9\u30b5\u30e9\uff1a\u30ab\u30dc\u30c1\u30e3\u306e\u6709\u671b\u306a\u6cbb\u7642\u52b9\u679c"},"content":{"rendered":"\n<p class=\"has-text-align-center\"><sup>\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u6027\u8131\u6bdb\u75c7\uff08<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/about_natural-pro\/\">AGA<\/a>\uff09\u306f\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u300c\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u300d\u304c\u300c\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u300d\u306b\u5909\u63db\u3055\u308c\u308b\u3053\u3068\u3067\u8d77\u3053\u308a\u307e\u3059\u3002\u3053\u306e\u5909\u63db\u3092\u4fc3\u3059\u9175\u7d20\u300c5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u300d\u306b\u306f\u8907\u6570\u306e\u30bf\u30a4\u30d7\u304c\u3042\u308a\u3001\u7279\u306bSRD5A1\u3001SRD5A2\u304cAGA\u306e\u539f\u56e0\u3068\u3057\u3066\u91cd\u8981\u3067\u3059\u3002\u307e\u305f\u8fd1\u5e74\u3001\u5929\u7136\u7531\u6765\u306e\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u6cb9\u3082\u6ce8\u76ee\u3055\u308c\u3001\u526f\u4f5c\u7528\u304c\u5c11\u306a\u3044\u65b0\u305f\u306a\u6cbb\u7642\u306e\u53ef\u80fd\u6027\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306fAGA\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u5206\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/sup><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u6027\u8131\u6bdb\u75c7\uff08Androgenetic Alopecia\uff09\u306e\u539f\u56e0\u3068\u75c5\u614b\u30e1\u30ab\u30cb\u30ba\u30e0<\/h2>\n\n\n\n<p>\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u6027\u8131\u6bdb\u75c7\uff08<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/about_natural-pro\/\">AGA<\/a>\uff09\u306f\u3001\u4e3b\u306b\u7537\u6027\u30db\u30eb\u30e2\u30f3\uff08\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\uff09\u306e\u4f5c\u7528\u304c\u539f\u56e0\u3068\u306a\u3063\u3066\u8d77\u3053\u308b\u8131\u6bdb\u75c7\u3067\u3059\u3002\u3053\u306eAGA\u306e\u767a\u75c7\u306b\u306f\u3001\u300c5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\uff085\u03b1-\u9084\u5143\u9175\u7d20\uff09\u300d\u3068\u3044\u3046\u9175\u7d20\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u30025\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306f\u4f53\u5185\u306e\u3055\u307e\u3056\u307e\u306a\u7d44\u7e54\u3084\u81d3\u5668\u306b\u5b58\u5728\u3057\u3066\u304a\u308a\u3001\u6027\u817a\uff08\u7cbe\u5de3\u3084\u5375\u5de3\uff09\u3001\u526f\u814e\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\uff08Central Nervous System, CNS\uff09\u306a\u3069\u3067\u4f5c\u3089\u308c\u305f\u30b9\u30c6\u30ed\u30a4\u30c9\u30db\u30eb\u30e2\u30f3\u306e\u524d\u99c6\u7269\u8cea\u3092\u3001\u3088\u308a\u6d3b\u6027\u304c\u9ad8\u3044\u30b9\u30c6\u30ed\u30a4\u30c9\u30db\u30eb\u30e2\u30f3\u306b\u5909\u63db\u3059\u308b\u50cd\u304d\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"640\" height=\"640\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24080918_s.jpg\" alt=\"AGA\" class=\"wp-image-6897\" style=\"width:262px;height:auto\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24080918_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24080918_s-300x300.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24080918_s-150x150.jpg 150w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24080918_s-485x485.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306e\u7a2e\u985e\u3068\u5f79\u5272\u306b\u3064\u3044\u3066<\/h3>\n\n\n\n<p>5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u306f\u3001\u4e3b\u306b5\u3064\u306e\u9175\u7d20\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u3046\u30613\u3064\uff08SRD5A1\u3001SRD5A2\u3001SRD5A3\uff09\u306f\u30b9\u30c6\u30ed\u30a4\u30c9\u30db\u30eb\u30e2\u30f3\u306e\u5909\u63db\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u6b8b\u308a\u306e2\u3064\uff08TECR\u304a\u3088\u3073TECR-like\uff09\u306f\u50cd\u304d\u304c\u307e\u3060\u5b8c\u5168\u306b\u306f\u89e3\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002SRD\u3068\u3044\u3046\u540d\u524d\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c95\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\uff08Steroid 5-alpha Reductase\uff09\u306e\u7565\u79f0\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img decoding=\"async\" width=\"1024\" height=\"324\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-130719-1024x324.png\" alt=\"T to DHT\" class=\"wp-image-6879\" style=\"width:678px;height:auto\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-130719-1024x324.png 1024w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-130719-300x95.png 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-130719-768x243.png 768w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-130719-1536x486.png 1536w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-130719-485x154.png 485w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-130719.png 1605w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n<p class=\"has-text-align-center\"><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8276191\/\"><sup>5-\u03b1-\u9084\u5143\u9175\u7d20\u306b\u3088\u308b\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08T\uff09\u304b\u3089\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u3078\u306e\u5909\u63db\u3002<\/sup><\/a><\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>SRD5A1\u3001SRD5A2\u3001SRD5A3\u306f\u305d\u308c\u305e\u308c\u5225\u3005\u306e\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u30b3\u30fc\u30c9\u3055\u308c\u3066\u304a\u308a\u3001\u6027\u8cea\u3084\u4f53\u5185\u3067\u306e\u5206\u5e03\u304c\u7570\u306a\u308a\u307e\u3059\u304c\u3001\u3044\u305a\u308c\u3082\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08Testosterone, T\uff09\u3068\u3044\u3046\u7537\u6027\u30db\u30eb\u30e2\u30f3\u3092\u3001\u3088\u308a\u6d3b\u6027\u306e\u9ad8\u3044\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08Dihydrotestosterone, DHT\uff09\u306b\u5909\u63db\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">DHT\u306e\u91cd\u8981\u6027\u3068AGA\u3078\u306e\u5f71\u97ff<\/h3>\n\n\n\n<p>\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u306f\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3088\u308a\u30825\u500d\u3082\u5f37\u304f\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08Androgen Receptor, AR\uff09\u306b\u7d50\u5408\u3057\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306b\u3088\u3063\u3066\u6d3b\u6027\u5316\u3055\u308c\u308b\u907a\u4f1d\u5b50\u3092\u8a98\u5c0e\u3059\u308b\u529b\u304c10\u500d\u3082\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u305f\u3081\u3001DHT\u306f\u7279\u5b9a\u306e\u7d44\u7e54\u3067\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u5f71\u97ff\u3092\u5897\u5e45\u3055\u305b\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>AGA\u306e\u9032\u884c\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50\u306b\u306f\u3001\u30c8\u30e9\u30f3\u30b9\u30d5\u30a9\u30fc\u30df\u30f3\u30b0\u6210\u9577\u56e0\u5b50\u03b21\uff08Transforming Growth Factor-beta 1, TGF-\u03b21\uff09\u3001\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f36\uff08Interleukin-6, IL-6\uff09\u3001\u30c7\u30a3\u30c3\u30af\u30b3\u30d51\uff08Dickkopf-1, DKK1\uff09\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306f\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306b\u3088\u3063\u3066\u8a98\u5c0e\u3055\u308c\u3001\u9aea\u306e\u6bdb\u306e\u6210\u9577\u3092\u6291\u5236\u3059\u308b\u50cd\u304d\u3092\u6301\u3063\u3066\u3044\u308b\u305f\u3081\u3001AGA\u306e\u9032\u884c\u306b\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24454605_s.jpg\" alt=\"\u30b7\u30e3\u30f3\u30d7\u30fc\" class=\"wp-image-6915\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24454605_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24454605_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24454605_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">SRD5A\u9175\u7d20\u306e\u4f53\u5185\u5206\u5e03\u3068AGA\u3068\u306e\u95a2\u9023\u6027<\/h3>\n\n\n\n<p>SRD5A\u9175\u7d20\u306f\u3001\u526f\u814e\u3001\u7cbe\u5de3\u3001\u80ce\u76e4\u3001\u305d\u3057\u3066\u7279\u306b\u76ae\u819a\u306a\u3069\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u5f71\u97ff\u3092\u53d7\u3051\u308b\u3055\u307e\u3056\u307e\u306a\u7d44\u7e54\u3067\u767a\u73fe\u3057\u3066\u3044\u307e\u3059\u3002SRD5A\u306e\u907a\u4f1d\u5b50\u304b\u3089\u4f5c\u3089\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u4e3b\u306b\u7d30\u80de\u5185\u306e\u5c0f\u80de\u4f53\uff08Endoplasmic Reticulum, ER\uff09\u306e\u819c\u306b\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>AGA\u306b\u7279\u306b\u91cd\u8981\u306a\u306e\u306f\u3001SRD5A1\u3068SRD5A2\u3068\u3044\u30462\u7a2e\u985e\u306e\u9175\u7d20\u3067\u3059\u3002\u3053\u308c\u3089\u306f\u3001\u76ae\u819a\u3084\u76ae\u819a\u4ed8\u5c5e\u5668\u5b98\uff08\u6bdb\u5305\u3001\u76ae\u8102\u817a\u3001\u6c57\u817a\uff09\u306b\u591a\u304f\u5b58\u5728\u3057\u3001AGA\u306e\u3042\u308b\u4eba\u3067\u306f\u984d\u90e8\u5206\u306e\u6bdb\u5305\uff08\u9aea\u3092\u3064\u304f\u308b\u7d44\u7e54\uff09\u3067\u306e\u767a\u73fe\u91cf\u304c\u7279\u306b\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001SRD5A1\u3068SRD5A2\u304cAGA\u306e\u4e3b\u8981\u306a\u539f\u56e0\u306e\u4e00\u3064\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306bSRD5A2\u306f\u3001AGA\u60a3\u8005\u306e\u982d\u76ae\u306e\u6bdb\u4e73\u982d\u7d30\u80de\uff08Dermal Papilla Cells, DPC\uff09\u3067\u4ed6\u306e\u90e8\u4f4d\u3088\u308a\u3082\u9ad8\u304f\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"20\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A1-hgtIdeo_genome_1fc224_8fef30-1024x20.png\" alt=\"SRD5A1 \" class=\"wp-image-6901\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A1-hgtIdeo_genome_1fc224_8fef30-1024x20.png 1024w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A1-hgtIdeo_genome_1fc224_8fef30-300x6.png 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A1-hgtIdeo_genome_1fc224_8fef30-768x15.png 768w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A1-hgtIdeo_genome_1fc224_8fef30-485x9.png 485w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A1-hgtIdeo_genome_1fc224_8fef30.png 1382w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"20\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A2-hgtIdeo_genome_201ce0_8ff290-1024x20.png\" alt=\"SRD5A2 \" class=\"wp-image-6904\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A2-hgtIdeo_genome_201ce0_8ff290-1024x20.png 1024w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A2-hgtIdeo_genome_201ce0_8ff290-300x6.png 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A2-hgtIdeo_genome_201ce0_8ff290-768x15.png 768w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A2-hgtIdeo_genome_201ce0_8ff290-485x9.png 485w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A2-hgtIdeo_genome_201ce0_8ff290.png 1382w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">SRD5A3\u306e\u5f79\u5272\u3068AGA\u306b\u304a\u3051\u308b\u53ef\u80fd\u6027<\/h3>\n\n\n\n<p>SRD5A3\u3068\u3044\u3046\u9175\u7d20\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306eN\u578b\u7cd6\u9396\u4ed8\u52a0\uff08N-\u30b0\u30ea\u30b3\u30b7\u30eb\u5316\uff09\u3068\u3044\u3046\u5225\u306e\u6a5f\u80fd\u3092\u4e3b\u306b\u6301\u3061\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u5909\u63db\u306b\u306f\u307b\u3068\u3093\u3069\u95a2\u308f\u3063\u3066\u3044\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3042\u308b\u7814\u7a76\u3067\u306f\u3001SRD5A3\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u3068\u3001\u7d30\u80de\u5185\u3067DHT\u304c\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306b\u5bfe\u3057\u3066\u76f8\u5bfe\u7684\u306b\u6e1b\u5c11\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u9593\u63a5\u7684\u306b\u30b9\u30c6\u30ed\u30a4\u30c9\u4ee3\u8b1d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u3082\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001SRD5A3\u306fSRD5A1\u3084SRD5A2\u3068\u6bd4\u8f03\u3059\u308b\u3068\u3001\u76ae\u819a\u3092\u542b\u3080\u672b\u68a2\u306e\u7d44\u7e54\u3067\u306e\u767a\u73fe\u91cf\u304c\u9ad8\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001SRD5A3\u306e\u767a\u73fe\u306f\u524d\u7acb\u817a\u304c\u3093\u3067\u9ad8\u304f\u306a\u3063\u3066\u304a\u308a\u3001\u524d\u7acb\u817a\u304c\u3093\u3068AGA\u306b\u306f\u4f55\u3089\u304b\u306e\u95a2\u9023\u6027\u304c\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u793a\u5506\u3059\u308b\u7814\u7a76\u3082\u3044\u304f\u3064\u304b\u3042\u308a\u307e\u3059\u3002AGA\u60a3\u8005\u306e\u9aea\u306e\u6bdb\u304b\u3089\u63a1\u53d6\u3055\u308c\u305f\u7d30\u80de\u3067\u3082SRD5A3\u306e\u767a\u73fe\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u304a\u308a\u3001SRD5A3\u304cAGA\u306e\u767a\u75c7\u306b\u3082\u4f55\u3089\u304b\u306e\u5f62\u3067\u95a2\u4e0e\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"20\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A3-hgtIdeo_genome_2050e4_8ff560-1024x20.png\" alt=\"SRD5A3 \" class=\"wp-image-6908\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A3-hgtIdeo_genome_2050e4_8ff560-1024x20.png 1024w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A3-hgtIdeo_genome_2050e4_8ff560-300x6.png 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A3-hgtIdeo_genome_2050e4_8ff560-768x15.png 768w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A3-hgtIdeo_genome_2050e4_8ff560-485x9.png 485w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/SRD5A3-hgtIdeo_genome_2050e4_8ff560.png 1382w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08AGA\uff09\u306e\u539f\u56e0\u3084\u9032\u884c\uff1a5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u9175\u7d20<\/h3>\n\n\n\n<p>\u7279\u306bSRD5A1\u3068SRD5A2\u306f\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3092\u5f37\u529b\u306aDHT\u3078\u3068\u5909\u63db\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u4f5c\u7528\u3092\u5897\u5e45\u3055\u305b\u3001\u9aea\u306e\u6bdb\u306e\u6210\u9577\u3092\u6291\u5236\u3057\u3001\u8131\u6bdb\u3092\u4fc3\u9032\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001SRD5A3\u3082\u76f4\u63a5\u7684\u306a\u30b9\u30c6\u30ed\u30a4\u30c9\u5909\u63db\u306f\u5c11\u306a\u3044\u306a\u304c\u3089\u3001AGA\u3068\u95a2\u9023\u304c\u3042\u308b\u53ef\u80fd\u6027\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u9175\u7d20\u306e\u4f5c\u7528\u3092\u8a73\u3057\u304f\u7406\u89e3\u3059\u308b\u3053\u3068\u304c\u3001AGA\u306e\u6cbb\u7642\u3084\u4e88\u9632\u306e\u305f\u3081\u306b\u3082\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32111233_s.jpg\" alt=\"\u9aea\u5973\u6027\" class=\"wp-image-6918\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32111233_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32111233_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32111233_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u6cbb\u7642\u85ac\uff1a\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\uff08Finasteride\uff09\u304a\u3088\u3073\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\uff08Dutasteride\uff09 \u306b\u3064\u3044\u3066<\/h2>\n\n\n\n<p>\u7d4c\u53e3\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u304a\u3088\u3073\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306f\u3001\u300c\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08Androgenetic Alopecia\uff1a<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/about_natural-pro\/\">AGA<\/a>\uff09\u300d\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u5e83\u304f\u627f\u8a8d\u3055\u308c\u3066\u304a\u308a\u3001\u75c5\u9662\u3067\u3082\u4e00\u822c\u7684\u306b\u51e6\u65b9\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u85ac\u306f\u300c5\u03b1\u9084\u5143\u9175\u7d20\uff085-alpha reductase\uff1a5-AR\uff09\u300d\u3068\u3044\u3046\u9175\u7d20\u306e\u50cd\u304d\u3092\u7af6\u5408\u7684\u306b\u963b\u5bb3\u3059\u308b\u4f5c\u7528\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u9175\u7d20\u306f\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u4e00\u7a2e\u3067\u3042\u308b\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3092\u3001\u3088\u308a\u5f37\u529b\u306a\u4f5c\u7528\u3092\u6301\u3064\u300c\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08Dihydrotestosterone\uff1aDHT\uff09\u300d\u3078\u3068\u5909\u63db\u3059\u308b\u50cd\u304d\u3092\u3057\u3066\u304a\u308a\u3001DHT\u306f\u4e0a\u8ff0\u306e\u901a\u308a\u3001\u8131\u6bdb\u3092\u5f15\u304d\u8d77\u3053\u3059\u4e3b\u306a\u539f\u56e0\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"381\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/finasteride-and-dustasteride-\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-131027-1024x381.png\" alt=\"finasteride and dustasteride \" class=\"wp-image-6885\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/finasteride-and-dustasteride-\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-131027-1024x381.png 1024w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/finasteride-and-dustasteride-\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-131027-300x112.png 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/finasteride-and-dustasteride-\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-131027-768x286.png 768w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/finasteride-and-dustasteride-\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-131027-1536x572.png 1536w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/finasteride-and-dustasteride-\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-131027-485x180.png 485w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/finasteride-and-dustasteride-\u30b9\u30af\u30ea\u30fc\u30f3\u30b7\u30e7\u30c3\u30c8-2025-03-18-131027.png 1720w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n<p class=\"has-text-align-center\"><sup><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8276191\/\">5\u03b1Ris\u306e\u5316\u5b66\u69cb\u9020\u3002\uff08a\uff09\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3001\uff08b\uff09\u30c0\u30b9\u30bf\u30b9\u30c6\u30ea\u30c9\u3002<\/a><\/sup><\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306f\u3001\u4e3b\u306b3\u7a2e\u985e\u5b58\u5728\u3059\u308b5\u03b1\u9084\u5143\u9175\u7d20\u306e\u3046\u3061\u3001\u300c\u30bf\u30a4\u30d72\uff08SRD5A2\uff09\u300d\u3068\u3044\u3046\u7a2e\u985e\u3092\u9078\u629e\u7684\u306b\u963b\u5bb3\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u305d\u308c\u3088\u308a\u306f\u3084\u3084\u5f31\u3044\u306a\u304c\u3089\u3082\u300c\u30bf\u30a4\u30d73\uff08SRD5A3\uff09\u300d\u306b\u3082\u4f5c\u7528\u3057\u307e\u3059\u304c\u3001\u300c\u30bf\u30a4\u30d71\uff08SRD5A1\uff09\u300d\u306b\u5bfe\u3057\u3066\u306f\u307b\u3068\u3093\u3069\u4f5c\u7528\u3057\u307e\u305b\u3093\u3002\u4e00\u65b9\u3067\u3001\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306f\u3001\u3053\u308c\u30893\u7a2e\u985e\u306e5\u03b1\u9084\u5143\u9175\u7d20\u3059\u3079\u3066\u3092\u5f37\u529b\u306b\u963b\u5bb3\u3059\u308b\u305f\u3081\u3001\u3088\u308a\u5e45\u5e83\u3044\u4f5c\u7528\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u85ac\u5264\u304c\u4f53\u5185\u3067\u534a\u5206\u306e\u91cf\u306b\u307e\u3067\u6e1b\u5c11\u3059\u308b\u306e\u306b\u304b\u304b\u308b\u6642\u9593\uff08\u534a\u6e1b\u671f\uff09\u304c\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306e\u65b9\u304c\u306f\u308b\u304b\u306b\u9577\u304f\u3001\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306e\u534a\u6e1b\u671f\u304c6\uff5e8\u6642\u9593\u306a\u306e\u306b\u5bfe\u3057\u3001\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306f4\uff5e5\u9031\u9593\u3068\u3001\u4f53\u5185\u306b\u9577\u304f\u7559\u307e\u308a\u3084\u3059\u3044\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"532\" height=\"468\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/crystal-structure-of-steroid-5-alpha-reductase-2-in-complex-with-finasteride.png\" alt=\"crystal structure of steroid 5-alpha-reductase 2 in complex with finasteride\" class=\"wp-image-6889\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/crystal-structure-of-steroid-5-alpha-reductase-2-in-complex-with-finasteride.png 532w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/crystal-structure-of-steroid-5-alpha-reductase-2-in-complex-with-finasteride-300x264.png 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/crystal-structure-of-steroid-5-alpha-reductase-2-in-complex-with-finasteride-485x427.png 485w\" sizes=\"(max-width: 532px) 100vw, 532px\" \/><\/figure><\/div>\n\n\n<p class=\"has-text-align-center\"><sup><a href=\"https:\/\/swissmodel.expasy.org\/repository\/uniprot\/P18405?csm=AEF9FD5521E43AC4\">3-\u30aa\u30ad\u30bd-5-\u30a2\u30eb\u30d5\u30a1-\u30b9\u30c6\u30ed\u30a4\u30c9 4-\u30c7\u30d2\u30c9\u30ed\u30b2\u30ca\u30fc\u30bc 1\uff083-oxo-5-alpha-steroid 4-dehydrogenase 1\uff09<\/a><\/sup><\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u7d4c\u53e35\u03b1\u9084\u5143\u9175\u7d20\u963b\u5bb3\u85ac\uff085-alpha reductase inhibitors\uff1a5-ARIs\uff09\u306f\u3001AGA\u6cbb\u7642\u85ac\u3068\u3057\u3066\u306e\u52b9\u679c\u304c\u533b\u5b66\u7684\u306b\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4e00\u65b9\u3067\u526f\u4f5c\u7528\u306e\u554f\u984c\u3082\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4ee3\u8868\u7684\u306a\u526f\u4f5c\u7528\u3068\u3057\u3066\u3001\u52c3\u8d77\u4e0d\u5168\uff08ED\uff09\u3084\u6027\u6b32\u306e\u6e1b\u9000\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u3001\u3053\u308c\u304c\u539f\u56e0\u3067\u6cbb\u7642\u3092\u9014\u4e2d\u3067\u65ad\u5ff5\u3059\u308b\u60a3\u8005\u3055\u3093\u3082\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u3053\u3067\u3001\u526f\u4f5c\u7528\u3092\u8efd\u6e1b\u3067\u304d\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u65b9\u6cd5\u3068\u3057\u3066\u3001\u982d\u76ae\u306b\u76f4\u63a5\u85ac\u5264\u3092\u5857\u5e03\u3059\u308b\u30bf\u30a4\u30d7\u306e\u300c\u5916\u7528\u85ac\u300d\u3068\u3057\u3066\u306e\u4f7f\u7528\u3082\u7814\u7a76\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u5916\u7528\u30bf\u30a4\u30d7\u306e5-ARIs\u3067\u3082\u8840\u6db2\u4e2d\u306eDHT\u6fc3\u5ea6\u3092\u5927\u5e45\u306b\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u6e1b\u5c11\u306e\u7a0b\u5ea6\u306f\u7d4c\u53e3\u85ac\u3068\u307b\u307c\u540c\u3058\u6c34\u6e96\u306b\u9054\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\uff08\u5916\u7528\u85ac\u3067\u7d0468\uff5e75\uff05\u3001\u7d4c\u53e3\u85ac\u3067\u7d0462\uff5e72\uff05\u306e\u6e1b\u5c11\uff09\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<p>\u5177\u4f53\u7684\u306a\u7814\u7a76\u4f8b\u3068\u3057\u3066\u3001\u6210\u4eba\u7537\u6027323\u540d\u3092\u5bfe\u8c61\u3068\u3057\u305f24\u9031\u9593\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u306f\u3001\u5916\u7528\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306f\u7d4c\u53e3\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3068\u540c\u7a0b\u5ea6\u306e\u52b9\u679c\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u3053\u3053\u3067\u306e\u52b9\u679c\u306f\u300c\u76ee\u6a19\u90e8\u4f4d\u306e\u6bdb\u9aea\u6570\uff08Target Area Hair Count\uff1aTAHC\uff09\u300d\u306e\u6539\u5584\u306b\u3088\u3063\u3066\u8a55\u4fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u5916\u7528\u85ac\u3067\u306f\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306e\u8840\u4e2d\u6fc3\u5ea6\u306e\u6700\u5927\u5024\uff08\u30d4\u30fc\u30af\u5024\uff09\u304c\u4f4e\u304f\u3001\u521d\u671f\u306e\u8840\u6db2\u4e2dDHT\u6fc3\u5ea6\u306e\u6e1b\u5c11\u304c\u6bd4\u8f03\u7684\u7de9\u3084\u304b\u3067\u3042\u308b\u305f\u3081\u3001\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u304c\u7d4c\u53e3\u85ac\u3088\u308a\u3082\u6291\u3048\u3089\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u5225\u306e\u8a66\u9a13\u3067\u306f\u3001\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\uff080.25\uff05\uff09\u3092\u5916\u7528\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\uff083\uff05\uff09\u3068\u4f75\u7528\u3057\u305f\u5834\u5408\u3001\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u5358\u72ec\u3068\u6bd4\u8f03\u3057\u3066\u300124\u9031\u9593\u5f8c\u306b\u9aea\u306e\u5bc6\u5ea6\u3084\u592a\u3055\u304c\u5927\u304d\u304f\u6539\u5584\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001\u5916\u7528\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3068\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u306e\u4f75\u7528\u306b\u306f\u76f8\u4e57\u7684\u306a\u52b9\u679c\uff08\u304a\u4e92\u3044\u306e\u52b9\u679c\u3092\u9ad8\u3081\u5408\u3046\u4f5c\u7528\uff09\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32100972_s.jpg\" alt=\"\u9aea\u5973\u6027\uff12\" class=\"wp-image-6921\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32100972_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32100972_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32100972_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u5973\u6027\u60a3\u8005\u306b\u304a\u3044\u3066\u306f\u3001\u7d4c\u53e3\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306f\u4f7f\u7528\u304c\u96e3\u3057\u3044\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u85ac\u5264\u306b\u3088\u3063\u3066\u306f\u300c\u591a\u6bdb\u75c7\uff08\u9854\u3084\u4f53\u306e\u6bdb\u304c\u5897\u3048\u308b\uff09\u300d\u3084\u300c\u6708\u7d4c\u4e0d\u9806\u300d\u306a\u3069\u306e\u526f\u4f5c\u7528\u304c\u8d77\u3053\u308a\u5f97\u308b\u305f\u3081\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u5973\u6027\u60a3\u8005\u306b\u3068\u3063\u3066\u3082\u3001\u3088\u308a\u5b89\u5168\u306a\u9078\u629e\u80a2\u3068\u3057\u3066\u5916\u7528\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u304c\u691c\u8a0e\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3042\u308b\u7814\u7a76\u3067\u306f\u3001\u9589\u7d4c\u5f8c\u306e\u5973\u602730\u540d\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3001\u5916\u7528\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\uff080.25\uff05\uff09\u3068\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\uff083\uff05\uff09\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u4f7f\u7528\u3057\u305f\u3068\u3053\u308d\u3001\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u5358\u72ec\u3068\u6bd4\u3079\u3001\u9aea\u306e\u5bc6\u5ea6\u3084\u592a\u3055\u306b\u6539\u5584\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002\u305f\u3060\u3057\u3001\u3053\u306e\u5206\u91ce\u306e\u7814\u7a76\u306f\u307e\u3060\u5341\u5206\u306b\u591a\u304f\u306a\u304f\u3001\u7814\u7a76\u3054\u3068\u306e\u7d50\u679c\u306b\u3082\u3070\u3089\u3064\u304d\u304c\u3042\u308b\u305f\u3081\u3001\u5973\u6027\u306b\u304a\u3051\u308b\u5916\u75285-ARIs\u306e\u4e00\u822c\u7684\u306a\u52b9\u679c\u3084\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u306f\u3001\u307e\u3060\u78ba\u304b\u306a\u7d50\u8ad6\u304c\u51fa\u3066\u3044\u307e\u305b\u3093\u3002\u307e\u305f\u5973\u6027\u306e\u8131\u6bdb\u75c7\u306e\u5834\u5408\u3001\u539f\u56e0\u304c\u3055\u307e\u3056\u307e\u3067\u8907\u96d1\u3067\u3042\u308b\u305f\u3081\u3001\u6cbb\u7642\u6cd5\u306e\u6709\u52b9\u6027\u3082\u614e\u91cd\u306b\u691c\u8a0e\u3055\u308c\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u30012024\u5e74\u306b\u884c\u308f\u308c\u305f\u300c\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\uff08\u3055\u307e\u3056\u307e\u306a\u7814\u7a76\u306e\u7d50\u679c\u3092\u7d71\u8a08\u7684\u306b\u7d71\u5408\u30fb\u5206\u6790\u3059\u308b\u624b\u6cd5\uff09\u300d\u306b\u3088\u308b\u3068\u3001\u7537\u6027\u578b\u8131\u6bdb\u75c7\u306e\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u306f\u3001\u7d4c\u53e35-ARIs\u304c\u4f9d\u7136\u3068\u3057\u3066\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u3001\u30dc\u30c4\u30ea\u30cc\u30b9\u6bd2\u7d20\uff08\u30dc\u30c8\u30c3\u30af\u30b9\uff09\u3001\u30de\u30a4\u30af\u30ed\u30cb\u30fc\u30c9\u30ea\u30f3\u30b0\uff08\u7d30\u304b\u3044\u91dd\u3092\u4f7f\u3063\u305f\u65bd\u8853\uff09\u3001\u5149\u6cbb\u7642\uff08\u30d5\u30a9\u30c8\u30d0\u30a4\u30aa\u30e2\u30b8\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\uff09\u306a\u3069\u306e\u4ee3\u66ff\u6cbb\u7642\u3088\u308a\u3082\u3001\u5358\u72ec\u306e\u85ac\u5264\u3068\u3057\u3066\u306f\u52b9\u679c\u304c\u9ad8\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u7d4c\u53e3\u85ac\u306f\u9577\u671f\u7684\u306a\u526f\u4f5c\u7528\u306e\u554f\u984c\u304c\u3042\u308b\u305f\u3081\u3001\u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u5916\u7528\u85ac\u3084\u3001\u85ac\u8349\u7531\u6765\u306e\u62bd\u51fa\u7269\u306a\u3069\u3001\u3088\u308a\u5b89\u5168\u3067\u4f7f\u3044\u3084\u3059\u3044\u4ee3\u66ff\u6cbb\u7642\u3078\u306e\u95a2\u5fc3\u304c\u9ad8\u307e\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"480\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32160041_s.jpg\" alt=\"\u30cf\u30fc\u30d6\u30a8\u30ad\u30b9\u85ac\" class=\"wp-image-6924\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32160041_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32160041_s-300x225.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32160041_s-485x364.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u30ab\u30dc\u30c1\u30e3\u3001\u30da\u30dd<\/h2>\n\n\n\n<p class=\"has-text-align-center\"><sup>Cucurbita pepo L.\u3000\u30af\u30af\u30eb\u30d3\u30bf \u30da\u30dd L<\/sup><\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" width=\"643\" height=\"454\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/Rplotpinkinbioactivecomponents.png\" alt=\"pumpkinbioactivecomponents\" class=\"wp-image-6875\" style=\"width:716px;height:auto\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/Rplotpinkinbioactivecomponents.png 643w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/Rplotpinkinbioactivecomponents-300x212.png 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/Rplotpinkinbioactivecomponents-485x342.png 485w\" sizes=\"(max-width: 643px) 100vw, 643px\" \/><\/figure>\n\n\n\n<p>\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u6cb9\uff08Pumpkin seed oil\u3001\u7565\u79f0\uff1aPSO\uff09\u306f\u3001\u30da\u30dd\u30ab\u30dc\u30c1\u30e3\uff08\u5b66\u540d\uff1aCucurbita pepo L.\uff09\u306e\u6955\u5186\u5f62\u306e\u7a2e\u5b50\u304b\u3089\u62bd\u51fa\u3055\u308c\u308b\u5929\u7136\u306e\u690d\u7269\u6cb9\u3067\u3001\u7279\u306b\u300c\u7537\u6027\u578b\u8131\u6bdb\u75c7\u300d\uff08androgenetic alopecia\u3001\u7565\u79f0\uff1a<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/about_natural-pro\/\">AGA<\/a>\uff09\u3068\u3044\u3046\u907a\u4f1d\u6027\u306e\u8131\u6bdb\u75c7\u72b6\u306b\u5bfe\u3057\u3001\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002PSO\u304c\u8131\u6bdb\u306e\u6539\u5584\u306b\u5f79\u7acb\u3064\u7406\u7531\u306f\u3001\u305d\u306e\u4e2d\u306b\u8c4a\u5bcc\u306b\u542b\u307e\u308c\u308b\u690d\u7269\u7531\u6765\u306e\u6709\u52b9\u6210\u5206\u304c\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002\u4e3b\u306a\u6210\u5206\u306b\u306f\u300c\u30d5\u30a3\u30c8\u30b9\u30c6\u30ed\u30fc\u30eb\u300d\uff08\u690d\u7269\u30b9\u30c6\u30ed\u30fc\u30eb\uff09\u3068\u547c\u3070\u308c\u308b\u5929\u7136\u5316\u5408\u7269\u7fa4\uff08\u4f8b\uff1a\u30c7\u30b9\u30e2\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u30ab\u30f3\u30da\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u30b9\u30c1\u30b0\u30de\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u03b2-\u30b7\u30c8\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u30b9\u30d4\u30ca\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u22067-\u30d5\u30a3\u30c8\u30b9\u30c6\u30ed\u30fc\u30eb\u306a\u3069\uff09\u3084\u3001\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u985e\u3001\u30c8\u30b3\u30d5\u30a7\u30ed\u30fc\u30eb\uff08\u30d3\u30bf\u30df\u30f3E\u7fa4\uff09\u3001\u30b9\u30af\u30a2\u30ec\u30f3\u3001\u305d\u3057\u3066\u30aa\u30ec\u30a4\u30f3\u9178\u3084\u30ea\u30ce\u30fc\u30eb\u9178\u306a\u3069\u306e\u91cd\u8981\u306a\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u304c\u8907\u5408\u7684\u306b\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u8131\u6bdb\u3084\u524d\u7acb\u817a\u75be\u60a3\u306b\u6df1\u304f\u95a2\u308f\u308b\u300c5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u300d\uff085-alpha reductase\u3001\u7565\u79f0\uff1a5\u03b1R\uff09\u3068\u3044\u3046\u9175\u7d20\u306e\u50cd\u304d\u3092\u6291\u5236\u3057\u307e\u3059\u3002\u3053\u306e\u9175\u7d20\u306f\u4f53\u5185\u3067\u7537\u6027\u30db\u30eb\u30e2\u30f3\u3092\u6d3b\u6027\u5316\u3059\u308b\u5f79\u5272\u304c\u3042\u308a\u3001AGA\u3084\u524d\u7acb\u817a\u80a5\u5927\u306e\u539f\u56e0\u306e\u4e00\u3064\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1001\" height=\"1024\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53664-1-17-20211202-1001x1024.jpg\" alt=\"Fig. 1. GC\u2013MS analysis of TPS in hull-less pumpkin seed oil. (A) Total ion chromatogram of TPS by GC\u2013MS. (B) Chemical structure of peaks (1\u20137) shown in (A). Peaks (1\u20137) were identified by comparing with NIST.14 standard library and defined in the text.\" class=\"wp-image-6872\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53664-1-17-20211202-1001x1024.jpg 1001w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53664-1-17-20211202-293x300.jpg 293w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53664-1-17-20211202-768x785.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53664-1-17-20211202-485x496.jpg 485w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53664-1-17-20211202.jpg 1418w\" sizes=\"(max-width: 1001px) 100vw, 1001px\" \/><\/figure><\/div>\n\n\n<p class=\"has-text-align-center\"><sup><a href=\"http:\/\/dx.doi.org\/10.29219\/fnr.v65.7537\">Food &amp; Nutrition Research 2021, 65: 7537 http:\/\/dx.doi.org\/10.29219\/fnr.v65.7537 \u56f31. \u6bbb\u306a\u3057\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u6cb9\u4e2d\u306eTPS\u306eGC-MS\u5206\u6790\u3002\uff08A\uff09GC-MS\u306b\u3088\u308bTPS\u306e\u5168\u30a4\u30aa\u30f3\u30af\u30ed\u30de\u30c8\u30b0\u30e9\u30e0\u3002\uff08B\uff09\uff08A\uff09\u306b\u793a\u3057\u305f\u30d4\u30fc\u30af\uff081\u301c7\uff09\u306e\u5316\u5b66\u69cb\u9020\u3002\u30d4\u30fc\u30af\uff081\u301c7\uff09\u306f\u3001NIST.14\u6a19\u6e96\u30e9\u30a4\u30d6\u30e9\u30ea\u3068\u6bd4\u8f03\u3057\u3066\u7279\u5b9a\u3055\u308c\u305f\u3002 <\/a><\/sup><\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u533b\u85ac\u54c1\u3068\u3057\u3066\u4e00\u822c\u7684\u306b\u4f7f\u308f\u308c\u308b\u300c5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u963b\u5bb3\u85ac\u300d\uff085-alpha reductase inhibitors\u3001\u7565\u79f0\uff1a5\u03b1Ris\uff09\u306e\u4ee3\u8868\u7684\u306a\u3082\u306e\u306b\u306f\u3001\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3068\u3044\u3046\u85ac\u5264\u304c\u3042\u308a\u307e\u3059\u3002\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306fAGA\u3084\u524d\u7acb\u817a\u75be\u60a3\u306e\u6cbb\u7642\u306b\u52b9\u679c\u7684\u3067\u3059\u304c\u3001\u526f\u4f5c\u7528\u3068\u3057\u3066\u6027\u6a5f\u80fd\u969c\u5bb3\uff08\u52c3\u8d77\u4e0d\u5168\u3084\u5c04\u7cbe\u969c\u5bb3\u3001\u6027\u6b32\u4f4e\u4e0b\uff09\u3084\u982d\u75db\u3001\u80c3\u8178\u306e\u4e0d\u8abf\u306a\u3069\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306a\u3069\u306e\u533b\u85ac\u54c1\u306f\u3001\u8efd\u5ea6\u306a\u524d\u7acb\u817a\u304c\u3093\u306e\u4e88\u9632\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u4e00\u65b9\u3067\u3001\u9032\u884c\u304c\u901f\u304f\u6cbb\u7642\u304c\u56f0\u96e3\u306a\u91cd\u75c7\u5ea6\u306e\u9ad8\u3044\u524d\u7acb\u817a\u304c\u3093\u306e\u767a\u751f\u3092\u4fc3\u3059\u30ea\u30b9\u30af\u304c\u3042\u308b\u3068\u3044\u3046\u8b70\u8ad6\u3082\u3042\u308a\u3001\u5b89\u5168\u6027\u306b\u61f8\u5ff5\u304c\u6301\u305f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u3046\u3057\u305f\u526f\u4f5c\u7528\u3078\u306e\u4e0d\u5b89\u304b\u3089\u3001\u3088\u308a\u5b89\u5168\u3067\u7a4f\u3084\u304b\u306a\u4f5c\u7528\u3092\u6301\u3064\u690d\u7269\u7531\u6765\u306e\u4ee3\u66ff\u54c1\u3078\u306e\u95a2\u5fc3\u304c\u9ad8\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4e2d\u3067\u3082\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u6cb9\u306f\u3001\u81e8\u5e8a\u7814\u7a76\u3067\u5b9f\u969b\u306b\u305d\u306e\u52b9\u679c\u3084\u5b89\u5168\u6027\u304c\u8a8d\u3081\u3089\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u6ce8\u76ee\u3055\u308c\u305f\u7814\u7a76\u3067\u306f\u3001\u8efd\u5ea6\uff5e\u4e2d\u7a0b\u5ea6\u306eAGA\u3092\u6301\u3064\u7537\u602776\u4eba\u306b\u5bfe\u3057\u3001PSO\u30921\u65e5400mg\u305a\u3064\u300124\u9031\u9593\u98f2\u3093\u3067\u3082\u3089\u3046\u81e8\u5e8a\u8a66\u9a13\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u8a66\u9a13\u306f\u3001\u5bfe\u8c61\u8005\u304c\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u304b\u507d\u85ac\uff08\u30d7\u30e9\u30bb\u30dc\uff09\u3092\u98f2\u3093\u3067\u3044\u308b\u304b\u308f\u304b\u3089\u306a\u3044\u3088\u3046\u306b\u3059\u308b\u300c\u4e8c\u91cd\u76f2\u691c\u6cd5\u300d\u3068\u547c\u3070\u308c\u308b\u65b9\u6cd5\u3067\u884c\u308f\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001PSO\u3092\u6442\u53d6\u3057\u305f\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u306b\u6bd4\u3079\u3066\u81ea\u5df1\u8a55\u4fa1\u306b\u3088\u308b\u6e80\u8db3\u5ea6\u304c\u9ad8\u307e\u308a\u3001\u9aea\u306e\u6bdb\u306e\u672c\u6570\u3082\u5e73\u5747\u306740\uff05\u5897\u52a0\u3057\u305f\u306e\u306b\u5bfe\u3057\u3001\u30d7\u30e9\u30bb\u30dc\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u306f10\uff05\u306b\u3068\u3069\u307e\u308a\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u526f\u4f5c\u7528\u306e\u767a\u751f\u983b\u5ea6\u306f\u30d7\u30e9\u30bb\u30dc\u7fa4\u3068\u5dee\u304c\u306a\u304f\u3001\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306e\u3088\u3046\u306a\u6027\u6a5f\u80fd\u969c\u5bb3\u306e\u5831\u544a\u3082\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"360\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32066162_s.jpg\" alt=\"\u30ab\u30dc\u30c1\u30e3\u5929\u3077\u3089\" class=\"wp-image-6928\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32066162_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32066162_s-300x169.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32066162_s-485x273.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u3055\u3089\u306b2020\u5e74\u306b\u306f\u3001\u300c\u5973\u6027\u578b\u8131\u6bdb\u75c7\u300d\uff08female pattern hair loss\u3001\u7565\u79f0\uff1aFPHL\uff09\u306e\u5973\u6027\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3082\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u6cb9\u3092\u982d\u76ae\u306b\u76f4\u63a5\u5857\u308b\u65b9\u6cd5\u3068\u3001\u73fe\u5728\u5e83\u304f\u4f7f\u308f\u308c\u3066\u3044\u308b\u30df\u30ce\u30ad\u30b7\u30b8\u30eb5\uff05\u6ce1\u72b6\u88fd\u5264\u306e\u52b9\u679c\u30923\u30f6\u6708\u9593\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u4e21\u30b0\u30eb\u30fc\u30d7\u3068\u3082\u9aea\u306e\u592a\u3055\u3084\u8cea\u306e\u591a\u69d8\u6027\u304c\u6539\u5584\u3057\u3001\u7d30\u304f\u5f31\u3044\u6bdb\uff08\u8edf\u6bdb\uff09\u304c\u6e1b\u5c11\u3057\u307e\u3057\u305f\u3002\u7279\u306bPSO\u3092\u4f7f\u7528\u3057\u305f\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u65b0\u3057\u304f\u7acb\u3061\u4e0a\u304c\u308b\u6bdb\u9aea\u306e\u6570\u304c\u660e\u3089\u304b\u306b\u5897\u3048\u3001\u8131\u6bdb\u75c7\u3078\u306e\u6709\u52b9\u6027\u304c\u671f\u5f85\u3067\u304d\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u305f\u3060\u3057\u3001\u3055\u3089\u306b\u898f\u6a21\u306e\u5927\u304d\u306a\u7814\u7a76\u304c\u5fc5\u8981\u3060\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>PSO\u304c\u306a\u305c\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u304b\u3068\u3044\u3046\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u7814\u7a76\u3082\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u4e2d\u5fc3\u7684\u306a\u4f5c\u7528\u306f5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306e\u6291\u5236\u3067\u3059\u304c\u3001\u305d\u308c\u4ee5\u5916\u306b\u3082\u708e\u75c7\u3092\u6291\u3048\u308b\u4f5c\u7528\uff08\u6297\u708e\u75c7\u4f5c\u7528\uff09\u3084\u3001\u7d30\u80de\u306b\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u308b\u6d3b\u6027\u9178\u7d20\u3092\u6d88\u53bb\u3059\u308b\u4f5c\u7528\uff08\u6297\u9178\u5316\u4f5c\u7528\uff09\u3082\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002\u5177\u4f53\u7684\u306b\u306f\u3001\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u306b\u542b\u307e\u308c\u308b\u30d5\u30a3\u30c8\u30b9\u30c6\u30ed\u30fc\u30eb\u304c\u3001\u8131\u6bdb\u3084\u524d\u7acb\u817a\u80a5\u5927\u306e\u539f\u56e0\u3068\u306a\u308b\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u4f5c\u7528\u3092\u6291\u5236\u3057\u305f\u308a\uff08\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08AR\uff09\u304a\u3088\u3073SRC-1\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u767a\u73fe\u3092\u6291\u3048\u308b\uff09\u3001\u7d30\u80de\u306e\u904e\u5270\u306a\u5897\u6b96\u3092\u6291\u5236\u3059\u308b\uff08ERK\u306e\u30ea\u30f3\u9178\u5316\u3092\u6e1b\u5c11\u3055\u305b\u308b\uff09\u307b\u304b\u3001\u7d30\u80de\u304c\u81ea\u7136\u306b\u6b7b\u306c\u4ed5\u7d44\u307f\uff08\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff09\u3092\u4fc3\u9032\u3059\u308b\u4f5c\u7528\uff08JNK\u304a\u3088\u3073p38\u7d4c\u8def\u3092\u901a\u3058\u3066Caspase-3\u3068\u3044\u3046\u9175\u7d20\u3092\u6d3b\u6027\u5316\u3059\u308b\uff09\u304c\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"826\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53674-1-17-20211202-1024x826.jpg\" alt=\"Fig. 6. The proposed mechanism of TPS ameliorating BPH in testosterone propionate-induced BPH rat. This graph is a summary of the mechanism speculated from this study. TPS: total phytosterols; 5AR: 5\u03b1-reductase; AR: androgen receptor; TGFBR: TGF-\u03b2 receptor; RTK: receptor tyrosine kinase.\" class=\"wp-image-6869\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53674-1-17-20211202-1024x826.jpg 1024w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53674-1-17-20211202-300x242.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53674-1-17-20211202-768x620.jpg 768w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53674-1-17-20211202-1536x1240.jpg 1536w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53674-1-17-20211202-485x391.jpg 485w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/7537-HTML-image-53674-1-17-20211202.jpg 1772w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n<p class=\"has-text-align-center\"><sup><a href=\"http:\/\/dx.doi.org\/10.29219\/fnr.v65.7537\">Food &amp; Nutrition Research 2021, 65: 7537 http:\/\/dx.doi.org\/10.29219\/fnr.v65.7537\u56f3 6. \u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u30d7\u30ed\u30d4\u30aa\u30cd\u30fc\u30c8\u8a98\u767a\u6027 BPH \u30e9\u30c3\u30c8\u306b\u304a\u3051\u308b TPS \u306b\u3088\u308b BPH \u6539\u5584\u306e\u63d0\u6848\u30e1\u30ab\u30cb\u30ba\u30e0\u3002\u3053\u306e\u30b0\u30e9\u30d5\u306f\u3001\u3053\u306e\u7814\u7a76\u304b\u3089\u63a8\u6e2c\u3055\u308c\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u8981\u7d04\u3067\u3059\u3002TPS: \u7dcf\u690d\u7269\u30b9\u30c6\u30ed\u30fc\u30eb\u30015AR: 5\u03b1-\u9084\u5143\u9175\u7d20\u3001AR: \u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\u3001TGFBR: TGF-\u03b2 \u53d7\u5bb9\u4f53\u3001RTK: \u53d7\u5bb9\u4f53\u30c1\u30ed\u30b7\u30f3\u30ad\u30ca\u30fc\u30bc\u3002<\/a><\/sup><\/p>\n\n\n\n<div style=\"height:18px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u524d\u7acb\u817a\u80a5\u5927\u75c7\uff08benign prostatic hyperplasia\u3001\u7565\u79f0\uff1aBPH\uff09\u3084\u904e\u6d3b\u52d5\u8180\u80f1\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u3082\u3001\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u304b\u3089\u62bd\u51fa\u3057\u305f\u6210\u5206\u306e\u5b89\u5168\u6027\u3084\u6709\u52b9\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u524d\u7acb\u817a\u80a5\u5927\u75c7\u306e\u7537\u602753\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u4e8c\u91cd\u76f2\u691c\u8a66\u9a13\u3067\u306f\u3001\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u30a8\u30ad\u30b9\u3068\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u88fd\u5264\uff08Curbicin\uff09\u306b\u3088\u3063\u3066\u3001\u6392\u5c3f\u6642\u306e\u5c3f\u306e\u52e2\u3044\u3084\u983b\u5c3f\u3001\u6b8b\u5c3f\u611f\u304c\u6539\u5584\u3055\u308c\u3001\u526f\u4f5c\u7528\u306e\u5831\u544a\u3082\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u3088\u3046\u306b\u3001\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u6cb9\u304a\u3088\u3073\u305d\u306e\u6709\u52b9\u6210\u5206\u3067\u3042\u308b\u30d5\u30a3\u30c8\u30b9\u30c6\u30ed\u30fc\u30eb\u306f\u3001AGA\u3084\u524d\u7acb\u817a\u80a5\u5927\u75c7\u306a\u3069\u7537\u6027\u30db\u30eb\u30e2\u30f3\u304c\u95a2\u4fc2\u3059\u308b\u75be\u60a3\u306b\u5bfe\u3057\u3001\u5b89\u5168\u3067\u52b9\u679c\u7684\u306a\u6cbb\u7642\u6cd5\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u8a73\u7d30\u306a\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e\u3084\u9577\u671f\u7684\u306a\u6709\u52b9\u6027\u3092\u78ba\u8a8d\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u4eca\u5f8c\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002\u73fe\u6642\u70b9\u3067\u306f\u3001\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u6cb9\u306f\u5f93\u6765\u306e\u533b\u85ac\u54c1\u306b\u6bd4\u3079\u3001\u526f\u4f5c\u7528\u304c\u5c11\u306a\u3044\u5929\u7136\u306e\u4ee3\u66ff\u307e\u305f\u306f\u88dc\u52a9\u7642\u6cd5\u3068\u3057\u3066\u5927\u304d\u306a\u671f\u5f85\u304c\u5bc4\u305b\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24740780_s.jpg\" alt=\"\u30ab\u30dc\u30c1\u30e3\u7a2e\" class=\"wp-image-6931\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24740780_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24740780_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/24740780_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\">\u30cf\u30e0\u3007\u90ce\u307f\u305f\u3044\u306b\u304b\u307c\u3061\u3083\u306e\u7a2e\u3092\u98df\u3079\u307e\u304f\u308b\u306e\u306f\u672c\u5f53\u306b\u52b9\u679c\u7684\u306a\u306e\u304b\uff1f<\/h3>\n\n\n\n<p>\u304b\u307c\u3061\u3083\u306e\u7a2e\u306b\u542b\u307e\u308c\u308b\u751f\u7406\u6d3b\u6027\u6210\u5206\uff08bioactive components\uff09\u304c\u3001\u5b9f\u969b\u306b\u4f53\u5185\u3067\u3069\u306e\u3088\u3046\u306a\u4ed5\u7d44\u307f\u3067\u50cd\u304d\uff08\u4f5c\u7528\u6a5f\u5e8f\uff1amechanism of action\uff09\u3001\u3069\u308c\u304f\u3089\u3044\u306e\u91cf\u3092\u6442\u53d6\u3059\u308c\u3070\u5341\u5206\u306a\u52b9\u679c\u304c\u5f97\u3089\u308c\u308b\u306e\u304b\u306b\u3064\u3044\u3066\u306f\u3001\u3055\u3089\u306b\u8a73\u7d30\u3067\u9577\u671f\u7684\u306a\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002\u3053\u3053\u3067\u8a00\u3046\u300c\u751f\u7406\u6d3b\u6027\u6210\u5206\u300d\u3068\u306f\u3001\u4eba\u306e\u4f53\u306b\u4f55\u3089\u304b\u306e\u826f\u3044\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u6210\u5206\u3092\u6307\u3057\u307e\u3059\u304c\u3001\u305d\u306e\u50cd\u304d\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u9577\u671f\u9593\u306b\u308f\u305f\u308b\u7814\u7a76\u3084\u8abf\u67fb\u3092\u91cd\u306d\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/30940904_s.jpg\" alt=\"\u3082\u3050\u3082\u3050\u30cf\u30e0\u30b9\u30bf\u30fc\" class=\"wp-image-6936\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/30940904_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/30940904_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/30940904_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u307e\u305f\u3001\u304b\u307c\u3061\u3083\u306e\u7a2e\u3092\u666e\u6bb5\u306e\u98df\u751f\u6d3b\u306b\u53d6\u308a\u5165\u308c\u308b\u3060\u3051\u3067\u306f\u3001<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/about_natural-pro\/\">AGA<\/a>\uff08\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff1aandrogenic alopecia\uff09\u3092\u5b8c\u5168\u306b\u6cbb\u7642\u3057\u305f\u308a\u3001\u533b\u5b66\u7684\u306b\u610f\u5473\u306e\u3042\u308b\u307b\u3069\u306e\u5927\u304d\u306a\u6539\u5584\u52b9\u679c\u3092\u5f97\u305f\u308a\u3059\u308b\u3053\u3068\u306f\u96e3\u3057\u3044\u3067\u3057\u3087\u3046\u3002AGA\u306f\u4e3b\u306b\u7537\u6027\u306b\u591a\u304f\u898b\u3089\u308c\u308b<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/about_natural-pro\/\">\u8584\u6bdb<\/a>\u3084\u8131\u6bdb\u75c7\u72b6\u306e\u4e00\u7a2e\u3067\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u304c\u95a2\u4e0e\u3057\u3066\u8d77\u304d\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u304b\u307c\u3061\u3083\u306e\u7a2e\u3092\u98df\u3079\u308b\u3053\u3068\u3067\u5065\u5eb7\u306b\u826f\u3044\u5f71\u97ff\u3092\u3082\u305f\u3089\u3059\u53ef\u80fd\u6027\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u73fe\u6bb5\u968e\u3067\u306f\u3001\u98df\u4e8b\u306b\u53d6\u308a\u5165\u308c\u308b\u7a0b\u5ea6\u306e\u91cf\u3067\u306fAGA\u3078\u306e\u5287\u7684\u306a\u6cbb\u7642\u52b9\u679c\u306f\u671f\u5f85\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u304b\u307c\u3061\u3083\u306e\u7a2e\u3092\u98df\u3079\u308b\u3053\u3068\u81ea\u4f53\u306b\u306f\u3001\u901a\u5e38\u3001\u526f\u4f5c\u7528\u306a\u3069\u306e\u5065\u5eb7\u30ea\u30b9\u30af\u306f\u307b\u3068\u3093\u3069\u306a\u304f\u3001\u6804\u990a\u4fa1\u306e\u9ad8\u3044\u5065\u5eb7\u7684\u306a\u9593\u98df\u3068\u3057\u3066\u3082\u9069\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"640\" height=\"485\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32054499_s.jpg\" alt=\"\u30cf\u30e0\u30b9\u30bf\u30fc\u592a\u90ce\" class=\"wp-image-6939\" style=\"width:500px;height:auto\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32054499_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32054499_s-300x227.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32054499_s-485x368.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u4eca\u5f8c\u3001\u7814\u7a76\u304c\u9032\u3080\u306b\u3064\u308c\u3066\u3001\u304b\u307c\u3061\u3083\u306e\u7a2e\u3084\u3001\u690d\u7269\u7531\u6765\u306e\u5225\u306e\u6210\u5206\u3092\u5229\u7528\u3057\u305f\u65b0\u3057\u3044\u6cbb\u7642\u65b9\u6cd5\u304c\u767b\u5834\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u73fe\u6642\u70b9\u3067\u306f\u660e\u78ba\u306a\u6cbb\u7642\u52b9\u679c\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u306a\u304f\u3066\u3082\u3001\u5c06\u6765\u7684\u306b\u306f\u690d\u7269\u7531\u6765\u306e\u6210\u5206\u3092\u6d3b\u7528\u3057\u305f\u65b0\u3057\u3044AGA\u6cbb\u7642\u6cd5\u304c\u78ba\u7acb\u3055\u308c\u308b\u3053\u3068\u3082\u671f\u5f85\u3055\u308c\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u8584\u6bdb\u3067\u60a9\u3093\u3067\u307e\u3059\u304c\uff0e\uff0e\uff0e<\/h2>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/30811153_s.jpg\" alt=\"\u306a\u3001\u306a\u3044\uff01\" class=\"wp-image-6942\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/30811153_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/30811153_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/30811153_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>FUE\u6cd5\uff08\u6bdb\u5305\u5358\u4f4d\u6458\u51fa\u6cd5\uff09\u306f\u3001\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/about_natural-pro\/\">AGA<\/a>\uff09\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u5e83\u304f\u8a8d\u3081\u3089\u308c\u3066\u3044\u308b\u52b9\u679c\u7684\u306a<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/\">\u690d\u6bdb<\/a>\u6280\u8853\u306e\u3072\u3068\u3064\u3067\u3059\u3002AGA\u306f\u300c\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u6027\u8131\u6bdb\u75c7\uff08Androgenetic Alopecia\uff09\u300d\u306e\u7565\u3067\u3001\u907a\u4f1d\u3084\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u5f71\u97ff\u3067\u8d77\u3053\u308b\u4e00\u822c\u7684\u306a\u8131\u6bdb\u75c7\u306e\u3053\u3068\u3092\u6307\u3057\u307e\u3059\u3002FUE\u6cd5\u306f\u3001\u4ed6\u306e\u6cbb\u7642\u6cd5\u3067\u5341\u5206\u306a\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u304b\u3063\u305f\u60a3\u8005\u306b\u3082\u7279\u306b\u52b9\u679c\u304c\u9ad8\u3044\u65b9\u6cd5\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5f93\u6765\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/\">\u690d\u6bdb<\/a>\u624b\u8853\u306b\u306f\u3001\u982d\u76ae\u304b\u3089\u5e2f\u72b6\u306b\u76ae\u819a\u3092\u5207\u308a\u53d6\u3063\u3066<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/minimally-invasive-hair-transplant\/\">\u79fb\u690d<\/a>\u7528\u306e\u6bdb\u5305\u3092\u63a1\u53d6\u3059\u308b\u65b9\u6cd5\uff08\u30ea\u30cb\u30a2\u30fb\u30b9\u30c8\u30ea\u30c3\u30d7\u6cd5\u3001Linear Strip Excision: LSE\uff09\u304c\u3042\u308a\u307e\u3059\u304c\u3001FUE\u6cd5\u3067\u306f\u982d\u76ae\u304b\u3089\u76f4\u63a5\u3001\u4e00\u3064\u3072\u3068\u3064\u306e\u6bdb\u5305\u5358\u4f4d\u3092\u624b\u4f5c\u696d\u3001\u6a5f\u68b0\u3001\u307e\u305f\u306f\u30ed\u30dc\u30c3\u30c8\u3092\u4f7f\u3063\u3066\u6458\u51fa\u3057\u307e\u3059\u3002\u3053\u306e\u65b9\u6cd5\u306b\u3088\u3063\u3066\u3001\u624b\u8853\u306b\u3088\u308b\u50b7\u3084\u8eab\u4f53\u3078\u306e\u8ca0\u62c5\u304c\u5927\u5e45\u306b\u8efd\u6e1b\u3055\u308c\u3001\u56de\u5fa9\u671f\u9593\u3082\u77ed\u7e2e\u3055\u308c\u308b\u4e0a\u3001LSE\u6cd5\u3067\u8d77\u304d\u308b\u5e2f\u72b6\u306e\u7dda\u72b6\u306e\u50b7\u8de1\uff08\u30c9\u30ca\u30fc\u50b7\uff09\u3092\u6b8b\u3055\u305a\u306b\u6e08\u307f\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u7279\u306b\u77ed\u3044\u30d8\u30a2\u30b9\u30bf\u30a4\u30eb\u3092\u597d\u3080\u4eba\u3084\u624b\u8853\u8de1\u3092\u76ee\u7acb\u305f\u305b\u305f\u304f\u306a\u3044\u4eba\u306b\u4eba\u6c17\u304c\u3042\u308a\u3001\u3053\u305320\u5e74\u9593\u3067\u4e16\u754c\u7684\u306b\u3082\u6025\u901f\u306b\u666e\u53ca\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32018467_s.jpg\" alt=\"\u9aea\" class=\"wp-image-6945\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32018467_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32018467_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32018467_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/\">\u690d\u6bdb<\/a>\u624b\u8853\u306e\u9577\u671f\u7684\u306a\u7d50\u679c\u3092\u8abf\u3079\u305f\u7814\u7a76\u3067\u306f\u3001\u65bd\u8853\u304b\u308910\u5e74\u4ee5\u4e0a\u7d4c\u904e\u3057\u305f\u60a3\u8005\u3067\u3082\u3001\u9ad8\u3044\u6e80\u8db3\u5ea6\u304c\u4e00\u8cab\u3057\u3066\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u300270\u540d\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3042\u308b\u5f8c\u308d\u5411\u304d\u8abf\u67fb\uff08\u904e\u53bb\u306b\u884c\u308f\u308c\u305f\u624b\u8853\u7d50\u679c\u3092\u5206\u6790\u3059\u308b\u7814\u7a76\uff09\u3067\u306f\u3001\u60a3\u8005\u306e\u6e80\u8db3\u5ea6\u304c\u8131\u6bdb\u6cbb\u7642\u85ac\u3001\u7279\u306b\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3068\u3044\u3046\u98f2\u307f\u85ac\u3092\u7d99\u7d9a\u3057\u3066\u4f7f\u7528\u3059\u308b\u304b\u3069\u3046\u304b\u306b\u5927\u304d\u304f\u5f71\u97ff\u3055\u308c\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u3053\u306e\u7814\u7a76\u3067\u306f\u3001<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/minimally-invasive-hair-transplant\/\">\u79fb\u690d<\/a>\u5f8c\u306e\u9aea\u306e\u6bdb\u306e\u5bc6\u5ea6\u304c5\u5e74\u9593\u3067\u304a\u3088\u305d4\uff5e6\uff05\u307b\u3069\u6e1b\u5c11\u3059\u308b\u3053\u3068\u3082\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u901a\u5e38\u300c\u5b89\u5168\u300d\u3068\u3055\u308c\u308b\u30c9\u30ca\u30fc\u90e8\u4f4d\uff08<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/minimally-invasive-hair-transplant\/\">\u79fb\u690d<\/a>\u7528\u306b\u63a1\u53d6\u3057\u305f\u982d\u76ae\u90e8\u5206\uff09\u304b\u3089\u53d6\u3063\u305f\u6bdb\u5305\u3067\u3042\u3063\u3066\u3082\u3001\u5fc5\u305a\u3057\u3082\u6c38\u4e45\u7684\u306b\u9aea\u3092\u7dad\u6301\u3067\u304d\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3001\u8853\u5f8c10\u5e74\u3092\u7d4c\u3066\u3082\u3001<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/minimally-invasive-hair-transplant\/\">\u79fb\u690d<\/a>\u90e8\u4f4d\u3068\u5143\u306e\u30c9\u30ca\u30fc\u90e8\u4f4d\u306e\u9aea\u306e\u6bdb\u306e\u592a\u3055\uff08\u6bdb\u9aea\u306e\u76f4\u5f84\uff09\u306b\u306f\u5927\u304d\u306a\u9055\u3044\u306f\u898b\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<p>\u307e\u305f\u3001\u5973\u6027\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3057\u305f\u7814\u7a76\u3067\u3082\u3001<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/\">\u690d\u6bdb<\/a>\u5f8c10\u5e74\u4ee5\u4e0a\u7d4c\u3063\u305f\u6642\u70b9\u3067\u9aea\u306e\u6bdb\u306e\u6e1b\u5c11\u304c\u6bd4\u8f03\u7684\u5b89\u5b9a\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u8abf\u67fb\u5bfe\u8c61\u3068\u306a\u3063\u305f\u4eba\u6570\u304c\u5c11\u306a\u304b\u3063\u305f\u305f\u3081\u3001\u3055\u3089\u306a\u308b\u8abf\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/31972705_s.jpg\" alt=\"\u9aea\u30b5\u30e9\u30b5\u30e9\" class=\"wp-image-6948\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/31972705_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/31972705_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/31972705_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<div style=\"height:17px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u7d50\u679c\u3092\u3055\u3089\u306b\u88cf\u4ed8\u3051\u308b\u6700\u8fd1\u306e\u7814\u7a76\u3068\u3057\u3066\u3001\u30a8\u30b8\u30d7\u30c8\u306e\u30e1\u30cc\u30d5\u30a3\u30a2\u5927\u5b66\u75c5\u9662\u30672019\u5e746\u6708\u304b\u30892021\u5e7410\u6708\u306e\u9593\u306b\u5b9f\u65bd\u3055\u308c\u305f\u524d\u5411\u304d\u30b3\u30db\u30fc\u30c8\u7814\u7a76\uff08\u3042\u308b\u4e00\u5b9a\u671f\u9593\u306b\u304a\u3044\u3066\u7279\u5b9a\u306e\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u3092\u7d99\u7d9a\u7684\u306b\u89b3\u5bdf\u3059\u308b\u7814\u7a76\uff09\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u3067\u306f\u3001\u5b9f\u969b\u306bFUE\u6cd5\u3067<a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/\">\u690d\u6bdb<\/a>\u624b\u8853\u3092\u53d7\u3051\u305f\u60a3\u8005\u306e\u6e80\u8db3\u5ea6\u304c\u8a55\u4fa1\u3055\u308c\u3001\u7d0490\uff05\u306e\u60a3\u8005\u304c\u8853\u5f8c\u306e\u898b\u305f\u76ee\u306b\u5927\u304d\u304f\u6539\u5584\u3092\u611f\u3058\u3066\u304a\u308a\u3001\u81ea\u5206\u81ea\u8eab\u304c\u4ee5\u524d\u3088\u308a\u3082\u82e5\u8fd4\u3063\u305f\u3088\u3046\u306b\u611f\u3058\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u6e80\u8db3\u5ea6\u306f\u300cFACE-Q\u300d\u3068\u3044\u3046\u8a55\u4fa1\u5c3a\u5ea6\u3092\u4f7f\u3063\u3066\u5ba2\u89b3\u7684\u306b\u6e2c\u5b9a\u3055\u308c\u3001FUE\u6cd5\u304cAGA\u60a3\u8005\u306e\u5fc3\u7406\u9762\u306b\u3082\u826f\u3044\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u4ee5\u4e0a\u306e\u3053\u3068\u304b\u3089\u3001FUE\u6cd5\u306fAGA\u306e\u9577\u671f\u7684\u306a\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u5e83\u304f\u9078\u3070\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u7279\u306b\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306a\u3069\u306e\u85ac\u5264\u3092\u7d99\u7d9a\u3057\u3066\u670d\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u9ad8\u3044\u60a3\u8005\u6e80\u8db3\u5ea6\u304c\u6301\u7d9a\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u6642\u9593\u304c\u7d4c\u3064\u306b\u3064\u308c\u3066\u9aea\u306e\u5bc6\u5ea6\u304c\u308f\u305a\u304b\u305a\u3064\u6e1b\u5c11\u3059\u308b\u50be\u5411\u304c\u3042\u308b\u305f\u3081\u3001\u826f\u3044\u7d50\u679c\u3092\u9577\u304f\u4fdd\u3064\u305f\u3081\u306b\u306f\u3001\u85ac\u306e\u670d\u7528\u3092\u7d99\u7d9a\u3059\u308b\u306a\u3069\u60a3\u8005\u81ea\u8eab\u304c\u6cbb\u7642\u306b\u3057\u3063\u304b\u308a\u53d6\u308a\u7d44\u3080\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u4eca\u5f8c\u3055\u3089\u306b\u591a\u304f\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u3001\u3088\u308a\u9577\u671f\u9593\u306e\u8ffd\u8de1\u8abf\u67fb\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u3053\u308c\u3089\u306e\u7d50\u679c\u3092\u3055\u3089\u306b\u8a73\u3057\u304f\u78ba\u8a8d\u3057\u3001\u3088\u308a\u826f\u3044\u6cbb\u7642\u6cd5\u306b\u3064\u306a\u3052\u3066\u3044\u304f\u5fc5\u8981\u304c\u3042\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32029542_s.jpg\" alt=\"\u3088\u308d\u3057\u304f\u304a\u9858\u3044\u3044\u305f\u3057\u307e\u3059\u3002\" class=\"wp-image-6912\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32029542_s.jpg 640w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32029542_s-300x200.jpg 300w, https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/wp-content\/uploads\/2025\/03\/32029542_s-485x324.jpg 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">\u30ad\u30fc\u30ef\u30fc\u30c9<\/h2>\n\n\n\n<p class=\"has-text-align-center\"><sup>\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u6027\u8131\u6bdb\u75c7, <a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/about_natural-pro\/\">AGA<\/a>, \u7537\u6027\u578b\u8131\u6bdb\u75c7, <a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/about_natural-pro\/\">\u8584\u6bdb<\/a>\u6cbb\u7642, 5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc, SRD5A1, SRD5A2, \u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3, DHT, \u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9, \u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9, \u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3, \u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u6cb9, \u30d5\u30a3\u30c8\u30b9\u30c6\u30ed\u30fc\u30eb, \u30df\u30ce\u30ad\u30b7\u30b8\u30eb, \u5916\u7528\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9, \u7537\u6027\u30db\u30eb\u30e2\u30f3, \u6bdb\u5305, \u6297\u9178\u5316\u4f5c\u7528, <a href=\"https:\/\/www.hiro-clinic.or.jp\/hair-transplantation\/\">\u690d\u6bdb<\/a>, \u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af<\/sup><\/p>\n\n\n<div class=\"custom-html\"><p><a class=\"category_bnr\" href=\"https:\/\/mypage-online-reservation.hiro-clinic.or.jp\/register?department=shokumou\"><br \/>\n<img decoding=\"async\" src=\"\/hair-transplantation\/wp-content\/uploads\/2025\/03\/column-bnr-2-1.webp\"><br \/>\n<\/a><\/p>\n<style>\n.category_bnr{\n  width:90%;\n  max-width:600px;\n  display:block;\n  margin:1rem auto;\n}\n<\/style>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">\u5f15\u7528\u6587\u732e<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/doi.org\/10.1111\/jocd.16362\">Gupta, A. K., Bamimore, M. A., Wang, T., &amp; Talukder, M. (2024). The impact of monotherapies for male androgenetic alopecia: A network meta-analysis study. <em>Journal of cosmetic dermatology<\/em>, <em>23<\/em>(9), 2964\u20132972. https:\/\/doi.org\/10.1111\/jocd.16362<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK555930\/\">Salisbury BH, Leslie SW, Tadi P. 5\u03b1-Reductase Inhibitors. [Updated 2024 Jun 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK555930\/<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1007\/s13555-023-00974-4\">Escamilla-Cruz, M., Maga\u00f1a, M., Escand\u00f3n-Perez, S. <em>et al.<\/em> Use of 5-Alpha Reductase Inhibitors in Dermatology: A Narrative Review. <em>Dermatol Ther (Heidelb)<\/em> 13, 1721\u20131731 (2023). https:\/\/doi.org\/10.1007\/s13555-023-00974-4<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/genenames.org\/data\/genegroup\/#!\/group\/1967\"><em>Gene group | hugo gene nomenclature committee<\/em>. (n.d.). Retrieved March 18, 2025, from https:\/\/genenames.org\/data\/genegroup\/#!\/group\/1967<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1038\/s41467-020-20675-2\">Han, Y., Zhuang, Q., Sun, B. <em>et al.<\/em> Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism. <em>Nat Commun<\/em> <strong>12<\/strong>, 449 (2021). https:\/\/doi.org\/10.1038\/s41467-020-20675-2<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1093\/nar\/gkae1010\">The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Res. 53:D609\u2013D617 (2025)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1093\/nar\/gky427\">Waterhouse, A., Bertoni, M., Bienert, S., Studer, G., Tauriello, G., Gumienny, R., Heer, F.T., de Beer, T.A.P., Rempfer, C., Bordoli, L., Lepore, R., Schwede, T. SWISS-MODEL: homology modelling of protein structures and complexes. Nucleic Acids Res. 46(W1), W296-W303 (2018).<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19517507\/\">Guex, N., Peitsch, M.C., Schwede, T. Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective. Electrophoresis 30, S162-S173 (2009).<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27899672\/\">Bienert, S., Waterhouse, A., de Beer, T.A.P., Tauriello, G., Studer, G., Bordoli, L., Schwede, T. The SWISS-MODEL Repository &#8211; new features and functionality. Nucleic Acids Res. 45, D313-D319 (2017).<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/swissmodel.expasy.org\/repository\/uniprot\/P18405?csm=AEF9FD5521E43AC4\"><em>P18405 | swiss-model repository<\/em>. (n.d.). Retrieved March 18, 2025, from https:\/\/swissmodel.expasy.org\/repository\/uniprot\/P18405?csm=AEF9FD5521E43AC4<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1155\/2012\/530121\">Azzouni, F., Godoy, A., Li, Y., &amp; Mohler, J. (2012). The 5 alpha-reductase isozyme family: A review of basic biology and their role in human diseases. <em>Advances in Urology<\/em>, <em>2012<\/em>, 1\u201318. https:\/\/doi.org\/10.1155\/2012\/530121<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.3390\/biology10040319\">Khantham, C., Yooin, W., Sringarm, K., Sommano, S. R., Jiranusornkul, S., Carmona, F. D., Nimlamool, W., Jantrawut, P., Rachtanapun, P., &amp; Ruksiriwanich, W. (2021). Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2. <em>Biology<\/em>, <em>10<\/em>(4), 319. https:\/\/doi.org\/10.3390\/biology10040319<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1111\/jocd.13976\">Ibrahim, I. M., Hasan, M. S., Elsabaa, K. I., &amp; Elsaie, M. L. (2021). Pumpkin seed oil vs. minoxidil 5% topical foam for the treatment of female pattern hair loss: a randomized comparative trial. Journal of Cosmetic Dermatology, 20(9), 2867-2873. https:\/\/doi.org\/10.1111\/jocd.13976<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1186\/1741-7015-9-105\">Hamilton, R. J., &amp; Freedland, S. J. (2011). 5-\u03b1 reductase inhibitors and prostate cancer prevention: where do we turn now?. <em>BMC medicine<\/em>, <em>9<\/em>, 105. https:\/\/doi.org\/10.1186\/1741-7015-9-105<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1155\/2014\/549721\">Cho, Y. H., Lee, S. Y., Jeong, D. W., Choi, E. J., Kim, Y. J., Lee, J. G., Yi, Y. H., &amp; Cha, H. S. (2014). Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. <em>Evidence-based complementary and alternative medicine : eCAM<\/em>, <em>2014<\/em>, 549721. https:\/\/doi.org\/10.1155\/2014\/549721<\/a><\/li>\n\n\n\n<li><span style=\"letter-spacing: 0.025em; background-color: var(--inner-content-bg); color: var(--main-text-color); font-family: var(--stk-base-font-family,&quot;\u6e38\u30b4\u30b7\u30c3\u30af&quot;,&quot;Yu Gothic&quot;,&quot;\u6e38\u30b4\u30b7\u30c3\u30af\u4f53&quot;,&quot;YuGothic&quot;,&quot;Hiragino Kaku Gothic ProN&quot;,Meiryo,sans-serif); font-size: var(--stk-base-font-size-pc,103%);\"><a href=\"https:\/\/doi.org\/10.1111\/j.1464-410x.1990.tb07199.x\">Carbin, B. E., Larsson, B., &amp; Lindahl, O. (1990). Treatment of benign prostatic hyperplasia with phytosterols. <\/a><\/span><i style=\"letter-spacing: 0.025em; background-color: var(--inner-content-bg); color: var(--main-text-color); font-family: var(--stk-base-font-family,&quot;\u6e38\u30b4\u30b7\u30c3\u30af&quot;,&quot;Yu Gothic&quot;,&quot;\u6e38\u30b4\u30b7\u30c3\u30af\u4f53&quot;,&quot;YuGothic&quot;,&quot;Hiragino Kaku Gothic ProN&quot;,Meiryo,sans-serif); font-size: var(--stk-base-font-size-pc,103%);\"><a href=\"https:\/\/doi.org\/10.1111\/j.1464-410x.1990.tb07199.x\">British journal of urology<\/a><\/i><span style=\"letter-spacing: 0.025em; background-color: var(--inner-content-bg); color: var(--main-text-color); font-family: var(--stk-base-font-family,&quot;\u6e38\u30b4\u30b7\u30c3\u30af&quot;,&quot;Yu Gothic&quot;,&quot;\u6e38\u30b4\u30b7\u30c3\u30af\u4f53&quot;,&quot;YuGothic&quot;,&quot;Hiragino Kaku Gothic ProN&quot;,Meiryo,sans-serif); font-size: var(--stk-base-font-size-pc,103%);\"><a href=\"https:\/\/doi.org\/10.1111\/j.1464-410x.1990.tb07199.x\">, <\/a><\/span><i style=\"letter-spacing: 0.025em; background-color: var(--inner-content-bg); color: var(--main-text-color); font-family: var(--stk-base-font-family,&quot;\u6e38\u30b4\u30b7\u30c3\u30af&quot;,&quot;Yu Gothic&quot;,&quot;\u6e38\u30b4\u30b7\u30c3\u30af\u4f53&quot;,&quot;YuGothic&quot;,&quot;Hiragino Kaku Gothic ProN&quot;,Meiryo,sans-serif); font-size: var(--stk-base-font-size-pc,103%);\"><a href=\"https:\/\/doi.org\/10.1111\/j.1464-410x.1990.tb07199.x\">66<\/a><\/i><span style=\"letter-spacing: 0.025em; background-color: var(--inner-content-bg); color: var(--main-text-color); font-family: var(--stk-base-font-family,&quot;\u6e38\u30b4\u30b7\u30c3\u30af&quot;,&quot;Yu Gothic&quot;,&quot;\u6e38\u30b4\u30b7\u30c3\u30af\u4f53&quot;,&quot;YuGothic&quot;,&quot;Hiragino Kaku Gothic ProN&quot;,Meiryo,sans-serif); font-size: var(--stk-base-font-size-pc,103%);\"><a href=\"https:\/\/doi.org\/10.1111\/j.1464-410x.1990.tb07199.x\">(6), 639\u2013641. https:\/\/doi.org\/10.1111\/j.1464-410x.1990.tb07199.x<\/a><\/span><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1080\/87559129.2018.1482496\">Ramak, P., &amp; Mahboubi, M. (2019). The beneficial effects of Pumpkin (<em>cucurbita pepo<\/em> l.) seed oil for health condition of men. <em>Food Reviews International<\/em>, <em>35<\/em>(2), 166\u2013176. https:\/\/doi.org\/10.1080\/87559129.2018.1482496<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1089\/jmf.2006.9.284\">Gossell-Williams, M., Davis, A., &amp; O\u2019Connor, N. (2006). Inhibition of testosterone-induced hyperplasia of the prostate of sprague-dawley rats by pumpkin seed oil. <em>Journal of Medicinal Food<\/em>, <em>9<\/em>(2), 284\u2013286. https:\/\/doi.org\/10.1089\/jmf.2006.9.284<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557634\/\">Kinter KJ, Amraei R, Anekar AA. Biochemistry, Dihydrotestosterone. [Updated 2023 Jul 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557634\/<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.29219\/fnr.v65.7537\">Kang, X., Chen, T., Zhou, J., Shen, P., Dai, S., Gao, C., Zhang, J., Xiong, X., &amp; Liu, D. (2021). Phytosterols in hull-less pumpkin seed oil, rich in \u22067-phytosterols, ameliorate benign prostatic hyperplasia by lowing 5\u03b1-reductase and regulating balance between cell proliferation and apoptosis in rats. <em>Food &amp; Nutrition Research<\/em>, <em>65<\/em>. https:\/\/doi.org\/10.29219\/fnr.v65.7537<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1111\/j.1749-6632.1960.tb40920.x\">Orentreich, N. (1959). Autografts in alopecias and other selected dermatological conditions.&nbsp;<em>Annals of the New York Academy of Sciences<\/em>,&nbsp;<em>83<\/em>(3), 463\u2013479. https:\/\/doi.org\/10.1111\/j.1749-6632.1960.tb40920.x<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1007\/978-3-031-74314-6_3\">Konstantinos, A. (2024). Hair Transplantation\u2014From the \u201cAncient\u201d 4 mm Plugs to the Latest Follicular Unit Excision Technique: 8 Decades of Painful Progress. In: Panagotacos, P.J., Maibach, H. (eds) Hair Loss. Updates in Clinical Dermatology. Springer, Cham. https:\/\/doi.org\/10.1007\/978-3-031-74314-6_3<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.33589\/33.5.157\">Pathomvanich, D., &amp; Mella, C. A. (2023). A ten-year retrospective analysis on the long-term survival of hair transplants. <em>International Society of Hair Restoration Surgery<\/em>, <em>33<\/em>(5), 157\u2013165. https:\/\/doi.org\/10.33589\/33.5.157<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.menoufia-med-j.com\/journal\/vol35\/iss3\/16\/\">Elsakka, D., ElKhesy, M., &amp; Gaber, M. (2022). Efficacy and evaluation of hair transplantation in patients with androgenic alopecia. <em>Menoufia Medical Journal<\/em>, <em>35<\/em>(3), 1043\u20131049. https:\/\/doi.org\/10.4103\/mmj.mmj_15_22<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u6027\u8131\u6bdb\u75c7\uff08AGA\uff09\u306f\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u300c\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u300d\u304c\u300c\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u300d\u306b\u5909\u63db\u3055\u308c\u308b\u3053\u3068\u3067\u8d77\u3053\u308a\u307e\u3059\u3002\u3053\u306e\u5909\u63db\u3092\u4fc3\u3059\u9175\u7d20\u300c5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u300d\u306b\u306f\u8907\u6570\u306e\u30bf\u30a4\u30d7\u304c\u3042\u308a\u3001\u7279\u306bSRD5A1\u3001SRD5A2\u304cAGA\u306e\u539f\u56e0\u3068\u3057\u3066\u91cd\u8981\u3067\u3059\u3002\u307e\u305f\u8fd1\u5e74\u3001\u5929\u7136\u7531\u6765\u306e\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u6cb9\u3082\u6ce8\u76ee\u3055\u308c\u3001\u526f\u4f5c\u7528\u304c\u5c11\u306a\u3044\u65b0\u305f\u306a\u6cbb\u7642\u306e\u53ef\u80fd\u6027\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306fAGA\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u5206\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002 \u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u6027\u8131\u6bdb\u75c7\uff08Androgenetic Alopecia\uff09\u306e\u539f\u56e0\u3068\u75c5\u614b\u30e1\u30ab\u30cb\u30ba\u30e0 \u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u6027\u8131\u6bdb\u75c7\uff08AGA\uff09\u306f\u3001\u4e3b\u306b\u7537\u6027\u30db\u30eb\u30e2\u30f3\uff08\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\uff09\u306e\u4f5c\u7528\u304c\u539f\u56e0\u3068\u306a\u3063\u3066\u8d77\u3053\u308b\u8131\u6bdb\u75c7\u3067\u3059\u3002\u3053\u306eAGA\u306e\u767a\u75c7\u306b\u306f\u3001\u300c5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\uff085\u03b1-\u9084\u5143\u9175\u7d20\uff09\u300d\u3068\u3044\u3046\u9175\u7d20\u304c\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u30025\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306f\u4f53\u5185\u306e\u3055\u307e\u3056\u307e\u306a\u7d44\u7e54\u3084\u81d3\u5668\u306b\u5b58\u5728\u3057\u3066\u304a\u308a\u3001\u6027\u817a\uff08\u7cbe\u5de3\u3084\u5375\u5de3\uff09\u3001\u526f\u814e\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\uff08Central Nervous System, CNS\uff09\u306a\u3069\u3067\u4f5c\u3089\u308c\u305f\u30b9\u30c6\u30ed\u30a4\u30c9\u30db\u30eb\u30e2\u30f3\u306e\u524d\u99c6\u7269\u8cea\u3092\u3001\u3088\u308a\u6d3b\u6027\u304c\u9ad8\u3044\u30b9\u30c6\u30ed\u30a4\u30c9\u30db\u30eb\u30e2\u30f3\u306b\u5909\u63db\u3059\u308b\u50cd\u304d\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002 5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306e\u7a2e\u985e\u3068\u5f79\u5272\u306b\u3064\u3044\u3066 5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u306f\u3001\u4e3b\u306b5\u3064\u306e\u9175\u7d20\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u3046\u30613\u3064\uff08SRD5A1\u3001SRD5A2\u3001SRD5A3\uff09\u306f\u30b9\u30c6\u30ed\u30a4\u30c9\u30db\u30eb\u30e2\u30f3\u306e\u5909\u63db\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u3001\u6b8b\u308a\u306e2\u3064\uff08TECR\u304a\u3088\u3073TECR-like\uff09\u306f\u50cd\u304d\u304c\u307e\u3060\u5b8c\u5168\u306b\u306f\u89e3\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002SRD\u3068\u3044\u3046\u540d\u524d\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c95\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\uff08Steroid 5-alpha Reductase\uff09\u306e\u7565\u79f0\u3067\u3059\u3002 5-\u03b1-\u9084\u5143\u9175\u7d20\u306b\u3088\u308b\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08T\uff09\u304b\u3089\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u3078\u306e\u5909\u63db\u3002 SRD5A1\u3001SRD5A2\u3001SRD5A3\u306f\u305d\u308c\u305e\u308c\u5225\u3005\u306e\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u30b3\u30fc\u30c9\u3055\u308c\u3066\u304a\u308a\u3001\u6027\u8cea\u3084\u4f53\u5185\u3067\u306e\u5206\u5e03\u304c\u7570\u306a\u308a\u307e\u3059\u304c\u3001\u3044\u305a\u308c\u3082\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08Testosterone, T\uff09\u3068\u3044\u3046\u7537\u6027\u30db\u30eb\u30e2\u30f3\u3092\u3001\u3088\u308a\u6d3b\u6027\u306e\u9ad8\u3044\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08Dihydrotestosterone, DHT\uff09\u306b\u5909\u63db\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002 DHT\u306e\u91cd\u8981\u6027\u3068AGA\u3078\u306e\u5f71\u97ff \u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08DHT\uff09\u306f\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3088\u308a\u30825\u500d\u3082\u5f37\u304f\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u53d7\u5bb9\u4f53\uff08Androgen Receptor, AR\uff09\u306b\u7d50\u5408\u3057\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306b\u3088\u3063\u3066\u6d3b\u6027\u5316\u3055\u308c\u308b\u907a\u4f1d\u5b50\u3092\u8a98\u5c0e\u3059\u308b\u529b\u304c10\u500d\u3082\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u305f\u3081\u3001DHT\u306f\u7279\u5b9a\u306e\u7d44\u7e54\u3067\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u5f71\u97ff\u3092\u5897\u5e45\u3055\u305b\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002 AGA\u306e\u9032\u884c\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50\u306b\u306f\u3001\u30c8\u30e9\u30f3\u30b9\u30d5\u30a9\u30fc\u30df\u30f3\u30b0\u6210\u9577\u56e0\u5b50\u03b21\uff08Transforming Growth Factor-beta 1, TGF-\u03b21\uff09\u3001\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f36\uff08Interleukin-6, IL-6\uff09\u3001\u30c7\u30a3\u30c3\u30af\u30b3\u30d51\uff08Dickkopf-1, DKK1\uff09\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306f\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306b\u3088\u3063\u3066\u8a98\u5c0e\u3055\u308c\u3001\u9aea\u306e\u6bdb\u306e\u6210\u9577\u3092\u6291\u5236\u3059\u308b\u50cd\u304d\u3092\u6301\u3063\u3066\u3044\u308b\u305f\u3081\u3001AGA\u306e\u9032\u884c\u306b\u6df1\u304f\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002 SRD5A\u9175\u7d20\u306e\u4f53\u5185\u5206\u5e03\u3068AGA\u3068\u306e\u95a2\u9023\u6027 SRD5A\u9175\u7d20\u306f\u3001\u526f\u814e\u3001\u7cbe\u5de3\u3001\u80ce\u76e4\u3001\u305d\u3057\u3066\u7279\u306b\u76ae\u819a\u306a\u3069\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u5f71\u97ff\u3092\u53d7\u3051\u308b\u3055\u307e\u3056\u307e\u306a\u7d44\u7e54\u3067\u767a\u73fe\u3057\u3066\u3044\u307e\u3059\u3002SRD5A\u306e\u907a\u4f1d\u5b50\u304b\u3089\u4f5c\u3089\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u4e3b\u306b\u7d30\u80de\u5185\u306e\u5c0f\u80de\u4f53\uff08Endoplasmic Reticulum, ER\uff09\u306e\u819c\u306b\u5b58\u5728\u3057\u3066\u3044\u307e\u3059\u3002 AGA\u306b\u7279\u306b\u91cd\u8981\u306a\u306e\u306f\u3001SRD5A1\u3068SRD5A2\u3068\u3044\u30462\u7a2e\u985e\u306e\u9175\u7d20\u3067\u3059\u3002\u3053\u308c\u3089\u306f\u3001\u76ae\u819a\u3084\u76ae\u819a\u4ed8\u5c5e\u5668\u5b98\uff08\u6bdb\u5305\u3001\u76ae\u8102\u817a\u3001\u6c57\u817a\uff09\u306b\u591a\u304f\u5b58\u5728\u3057\u3001AGA\u306e\u3042\u308b\u4eba\u3067\u306f\u984d\u90e8\u5206\u306e\u6bdb\u5305\uff08\u9aea\u3092\u3064\u304f\u308b\u7d44\u7e54\uff09\u3067\u306e\u767a\u73fe\u91cf\u304c\u7279\u306b\u9ad8\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001SRD5A1\u3068SRD5A2\u304cAGA\u306e\u4e3b\u8981\u306a\u539f\u56e0\u306e\u4e00\u3064\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u7279\u306bSRD5A2\u306f\u3001AGA\u60a3\u8005\u306e\u982d\u76ae\u306e\u6bdb\u4e73\u982d\u7d30\u80de\uff08Dermal Papilla Cells, DPC\uff09\u3067\u4ed6\u306e\u90e8\u4f4d\u3088\u308a\u3082\u9ad8\u304f\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 SRD5A3\u306e\u5f79\u5272\u3068AGA\u306b\u304a\u3051\u308b\u53ef\u80fd\u6027 SRD5A3\u3068\u3044\u3046\u9175\u7d20\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306eN\u578b\u7cd6\u9396\u4ed8\u52a0\uff08N-\u30b0\u30ea\u30b3\u30b7\u30eb\u5316\uff09\u3068\u3044\u3046\u5225\u306e\u6a5f\u80fd\u3092\u4e3b\u306b\u6301\u3061\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u5909\u63db\u306b\u306f\u307b\u3068\u3093\u3069\u95a2\u308f\u3063\u3066\u3044\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3042\u308b\u7814\u7a76\u3067\u306f\u3001SRD5A3\u306e\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u3068\u3001\u7d30\u80de\u5185\u3067DHT\u304c\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u306b\u5bfe\u3057\u3066\u76f8\u5bfe\u7684\u306b\u6e1b\u5c11\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u9593\u63a5\u7684\u306b\u30b9\u30c6\u30ed\u30a4\u30c9\u4ee3\u8b1d\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u3082\u6307\u6458\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u307e\u305f\u3001SRD5A3\u306fSRD5A1\u3084SRD5A2\u3068\u6bd4\u8f03\u3059\u308b\u3068\u3001\u76ae\u819a\u3092\u542b\u3080\u672b\u68a2\u306e\u7d44\u7e54\u3067\u306e\u767a\u73fe\u91cf\u304c\u9ad8\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001SRD5A3\u306e\u767a\u73fe\u306f\u524d\u7acb\u817a\u304c\u3093\u3067\u9ad8\u304f\u306a\u3063\u3066\u304a\u308a\u3001\u524d\u7acb\u817a\u304c\u3093\u3068AGA\u306b\u306f\u4f55\u3089\u304b\u306e\u95a2\u9023\u6027\u304c\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u793a\u5506\u3059\u308b\u7814\u7a76\u3082\u3044\u304f\u3064\u304b\u3042\u308a\u307e\u3059\u3002AGA\u60a3\u8005\u306e\u9aea\u306e\u6bdb\u304b\u3089\u63a1\u53d6\u3055\u308c\u305f\u7d30\u80de\u3067\u3082SRD5A3\u306e\u767a\u73fe\u304c\u9ad8\u304f\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u3066\u304a\u308a\u3001SRD5A3\u304cAGA\u306e\u767a\u75c7\u306b\u3082\u4f55\u3089\u304b\u306e\u5f62\u3067\u95a2\u4e0e\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08AGA\uff09\u306e\u539f\u56e0\u3084\u9032\u884c\uff1a5\u03b1\u30ea\u30c0\u30af\u30bf\u30fc\u30bc\u9175\u7d20 \u7279\u306bSRD5A1\u3068SRD5A2\u306f\u3001\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3092\u5f37\u529b\u306aDHT\u3078\u3068\u5909\u63db\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u4f5c\u7528\u3092\u5897\u5e45\u3055\u305b\u3001\u9aea\u306e\u6bdb\u306e\u6210\u9577\u3092\u6291\u5236\u3057\u3001\u8131\u6bdb\u3092\u4fc3\u9032\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001SRD5A3\u3082\u76f4\u63a5\u7684\u306a\u30b9\u30c6\u30ed\u30a4\u30c9\u5909\u63db\u306f\u5c11\u306a\u3044\u306a\u304c\u3089\u3001AGA\u3068\u95a2\u9023\u304c\u3042\u308b\u53ef\u80fd\u6027\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u9175\u7d20\u306e\u4f5c\u7528\u3092\u8a73\u3057\u304f\u7406\u89e3\u3059\u308b\u3053\u3068\u304c\u3001AGA\u306e\u6cbb\u7642\u3084\u4e88\u9632\u306e\u305f\u3081\u306b\u3082\u91cd\u8981\u3067\u3059\u3002 \u6cbb\u7642\u85ac\uff1a\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\uff08Finasteride\uff09\u304a\u3088\u3073\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\uff08Dutasteride\uff09 \u306b\u3064\u3044\u3066 \u7d4c\u53e3\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u304a\u3088\u3073\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306f\u3001\u300c\u7537\u6027\u578b\u8131\u6bdb\u75c7\uff08Androgenetic Alopecia\uff1aAGA\uff09\u300d\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u5e83\u304f\u627f\u8a8d\u3055\u308c\u3066\u304a\u308a\u3001\u75c5\u9662\u3067\u3082\u4e00\u822c\u7684\u306b\u51e6\u65b9\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u85ac\u306f\u300c5\u03b1\u9084\u5143\u9175\u7d20\uff085-alpha reductase\uff1a5-AR\uff09\u300d\u3068\u3044\u3046\u9175\u7d20\u306e\u50cd\u304d\u3092\u7af6\u5408\u7684\u306b\u963b\u5bb3\u3059\u308b\u4f5c\u7528\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u9175\u7d20\u306f\u3001\u7537\u6027\u30db\u30eb\u30e2\u30f3\u306e\u4e00\u7a2e\u3067\u3042\u308b\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\u3092\u3001\u3088\u308a\u5f37\u529b\u306a\u4f5c\u7528\u3092\u6301\u3064\u300c\u30b8\u30d2\u30c9\u30ed\u30c6\u30b9\u30c8\u30b9\u30c6\u30ed\u30f3\uff08Dihydrotestosterone\uff1aDHT\uff09\u300d\u3078\u3068\u5909\u63db\u3059\u308b\u50cd\u304d\u3092\u3057\u3066\u304a\u308a\u3001DHT\u306f\u4e0a\u8ff0\u306e\u901a\u308a\u3001\u8131\u6bdb\u3092\u5f15\u304d\u8d77\u3053\u3059\u4e3b\u306a\u539f\u56e0\u306e\u4e00\u3064\u3067\u3059\u3002 5\u03b1Ris\u306e\u5316\u5b66\u69cb\u9020\u3002\uff08a\uff09\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3001\uff08b\uff09\u30c0\u30b9\u30bf\u30b9\u30c6\u30ea\u30c9\u3002 \u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306f\u3001\u4e3b\u306b3\u7a2e\u985e\u5b58\u5728\u3059\u308b5\u03b1\u9084\u5143\u9175\u7d20\u306e\u3046\u3061\u3001\u300c\u30bf\u30a4\u30d72\uff08SRD5A2\uff09\u300d\u3068\u3044\u3046\u7a2e\u985e\u3092\u9078\u629e\u7684\u306b\u963b\u5bb3\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u305d\u308c\u3088\u308a\u306f\u3084\u3084\u5f31\u3044\u306a\u304c\u3089\u3082\u300c\u30bf\u30a4\u30d73\uff08SRD5A3\uff09\u300d\u306b\u3082\u4f5c\u7528\u3057\u307e\u3059\u304c\u3001\u300c\u30bf\u30a4\u30d71\uff08SRD5A1\uff09\u300d\u306b\u5bfe\u3057\u3066\u306f\u307b\u3068\u3093\u3069\u4f5c\u7528\u3057\u307e\u305b\u3093\u3002\u4e00\u65b9\u3067\u3001\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306f\u3001\u3053\u308c\u30893\u7a2e\u985e\u306e5\u03b1\u9084\u5143\u9175\u7d20\u3059\u3079\u3066\u3092\u5f37\u529b\u306b\u963b\u5bb3\u3059\u308b\u305f\u3081\u3001\u3088\u308a\u5e45\u5e83\u3044\u4f5c\u7528\u304c\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u85ac\u5264\u304c\u4f53\u5185\u3067\u534a\u5206\u306e\u91cf\u306b\u307e\u3067\u6e1b\u5c11\u3059\u308b\u306e\u306b\u304b\u304b\u308b\u6642\u9593\uff08\u534a\u6e1b\u671f\uff09\u304c\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306e\u65b9\u304c\u306f\u308b\u304b\u306b\u9577\u304f\u3001\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306e\u534a\u6e1b\u671f\u304c6\uff5e8\u6642\u9593\u306a\u306e\u306b\u5bfe\u3057\u3001\u30c7\u30e5\u30bf\u30b9\u30c6\u30ea\u30c9\u306f4\uff5e5\u9031\u9593\u3068\u3001\u4f53\u5185\u306b\u9577\u304f\u7559\u307e\u308a\u3084\u3059\u3044\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002 3-\u30aa\u30ad\u30bd-5-\u30a2\u30eb\u30d5\u30a1-\u30b9\u30c6\u30ed\u30a4\u30c9 4-\u30c7\u30d2\u30c9\u30ed\u30b2\u30ca\u30fc\u30bc 1\uff083-oxo-5-alpha-steroid 4-dehydrogenase 1\uff09 \u3053\u308c\u3089\u306e\u7d4c\u53e35\u03b1\u9084\u5143\u9175\u7d20\u963b\u5bb3\u85ac\uff085-alpha reductase inhibitors\uff1a5-ARIs\uff09\u306f\u3001AGA\u6cbb\u7642\u85ac\u3068\u3057\u3066\u306e\u52b9\u679c\u304c\u533b\u5b66\u7684\u306b\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4e00\u65b9\u3067\u526f\u4f5c\u7528\u306e\u554f\u984c\u3082\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4ee3\u8868\u7684\u306a\u526f\u4f5c\u7528\u3068\u3057\u3066\u3001\u52c3\u8d77\u4e0d\u5168\uff08ED\uff09\u3084\u6027\u6b32\u306e\u6e1b\u9000\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u3001\u3053\u308c\u304c\u539f\u56e0\u3067\u6cbb\u7642\u3092\u9014\u4e2d\u3067\u65ad\u5ff5\u3059\u308b\u60a3\u8005\u3055\u3093\u3082\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u3053\u3067\u3001\u526f\u4f5c\u7528\u3092\u8efd\u6e1b\u3067\u304d\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u65b9\u6cd5\u3068\u3057\u3066\u3001\u982d\u76ae\u306b\u76f4\u63a5\u85ac\u5264\u3092\u5857\u5e03\u3059\u308b\u30bf\u30a4\u30d7\u306e\u300c\u5916\u7528\u85ac\u300d\u3068\u3057\u3066\u306e\u4f7f\u7528\u3082\u7814\u7a76\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u5916\u7528\u30bf\u30a4\u30d7\u306e5-ARIs\u3067\u3082\u8840\u6db2\u4e2d\u306eDHT\u6fc3\u5ea6\u3092\u5927\u5e45\u306b\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u6e1b\u5c11\u306e\u7a0b\u5ea6\u306f\u7d4c\u53e3\u85ac\u3068\u307b\u307c\u540c\u3058\u6c34\u6e96\u306b\u9054\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\uff08\u5916\u7528\u85ac\u3067\u7d0468\uff5e75\uff05\u3001\u7d4c\u53e3\u85ac\u3067\u7d0462\uff5e72\uff05\u306e\u6e1b\u5c11\uff09\u3002 \u5177\u4f53\u7684\u306a\u7814\u7a76\u4f8b\u3068\u3057\u3066\u3001\u6210\u4eba\u7537\u6027323\u540d\u3092\u5bfe\u8c61\u3068\u3057\u305f24\u9031\u9593\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u306f\u3001\u5916\u7528\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306f\u7d4c\u53e3\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3068\u540c\u7a0b\u5ea6\u306e\u52b9\u679c\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u3053\u3053\u3067\u306e\u52b9\u679c\u306f\u300c\u76ee\u6a19\u90e8\u4f4d\u306e\u6bdb\u9aea\u6570\uff08Target Area Hair Count\uff1aTAHC\uff09\u300d\u306e\u6539\u5584\u306b\u3088\u3063\u3066\u8a55\u4fa1\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u5916\u7528\u85ac\u3067\u306f\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306e\u8840\u4e2d\u6fc3\u5ea6\u306e\u6700\u5927\u5024\uff08\u30d4\u30fc\u30af\u5024\uff09\u304c\u4f4e\u304f\u3001\u521d\u671f\u306e\u8840\u6db2\u4e2dDHT\u6fc3\u5ea6\u306e\u6e1b\u5c11\u304c\u6bd4\u8f03\u7684\u7de9\u3084\u304b\u3067\u3042\u308b\u305f\u3081\u3001\u526f\u4f5c\u7528\u306e\u30ea\u30b9\u30af\u304c\u7d4c\u53e3\u85ac\u3088\u308a\u3082\u6291\u3048\u3089\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u5225\u306e\u8a66\u9a13\u3067\u306f\u3001\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\uff080.25\uff05\uff09\u3092\u5916\u7528\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\uff083\uff05\uff09\u3068\u4f75\u7528\u3057\u305f\u5834\u5408\u3001\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u5358\u72ec\u3068\u6bd4\u8f03\u3057\u3066\u300124\u9031\u9593\u5f8c\u306b\u9aea\u306e\u5bc6\u5ea6\u3084\u592a\u3055\u304c\u5927\u304d\u304f\u6539\u5584\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u7d50\u679c\u304b\u3089\u3001\u5916\u7528\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u3068\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u306e\u4f75\u7528\u306b\u306f\u76f8\u4e57\u7684\u306a\u52b9\u679c\uff08\u304a\u4e92\u3044\u306e\u52b9\u679c\u3092\u9ad8\u3081\u5408\u3046\u4f5c\u7528\uff09\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u5973\u6027\u60a3\u8005\u306b\u304a\u3044\u3066\u306f\u3001\u7d4c\u53e3\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u306f\u4f7f\u7528\u304c\u96e3\u3057\u3044\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u85ac\u5264\u306b\u3088\u3063\u3066\u306f\u300c\u591a\u6bdb\u75c7\uff08\u9854\u3084\u4f53\u306e\u6bdb\u304c\u5897\u3048\u308b\uff09\u300d\u3084\u300c\u6708\u7d4c\u4e0d\u9806\u300d\u306a\u3069\u306e\u526f\u4f5c\u7528\u304c\u8d77\u3053\u308a\u5f97\u308b\u305f\u3081\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u5973\u6027\u60a3\u8005\u306b\u3068\u3063\u3066\u3082\u3001\u3088\u308a\u5b89\u5168\u306a\u9078\u629e\u80a2\u3068\u3057\u3066\u5916\u7528\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\u304c\u691c\u8a0e\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3042\u308b\u7814\u7a76\u3067\u306f\u3001\u9589\u7d4c\u5f8c\u306e\u5973\u602730\u540d\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3001\u5916\u7528\u30d5\u30a3\u30ca\u30b9\u30c6\u30ea\u30c9\uff080.25\uff05\uff09\u3068\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\uff083\uff05\uff09\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u4f7f\u7528\u3057\u305f\u3068\u3053\u308d\u3001\u30df\u30ce\u30ad\u30b7\u30b8\u30eb\u5358\u72ec\u3068\u6bd4\u3079\u3001\u9aea\u306e\u5bc6\u5ea6\u3084\u592a\u3055\u306b\u6539\u5584\u304c\u898b\u3089\u308c\u307e\u3057\u305f\u3002\u305f\u3060\u3057\u3001\u3053\u306e\u5206\u91ce\u306e\u7814\u7a76\u306f\u307e\u3060\u5341\u5206\u306b\u591a\u304f\u306a\u304f\u3001\u7814\u7a76\u3054\u3068\u306e\u7d50\u679c\u306b\u3082\u3070\u3089\u3064\u304d\u304c\u3042\u308b\u305f\u3081\u3001\u5973\u6027\u306b\u304a\u3051\u308b\u5916\u75285-ARIs\u306e\u4e00\u822c\u7684\u306a\u52b9\u679c\u3084\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u306f\u3001\u307e\u3060\u78ba\u304b\u306a\u7d50\u8ad6\u304c\u51fa\u3066\u3044\u307e\u305b\u3093\u3002\u307e\u305f\u5973\u6027\u306e\u8131\u6bdb\u75c7\u306e\u5834\u5408\u3001\u539f\u56e0\u304c\u3055\u307e\u3056\u307e\u3067\u8907\u96d1\u3067\u3042\u308b\u305f\u3081\u3001\u6cbb\u7642\u6cd5\u306e\u6709\u52b9\u6027\u3082\u614e\u91cd\u306b\u691c\u8a0e\u3055\u308c\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002 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