{"id":2686,"date":"2024-08-28T13:17:16","date_gmt":"2024-08-28T04:17:16","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nippt\/%e3%83%90%e3%83%8b%e3%82%b7%e3%83%b3%e3%82%b0%e3%83%84%e3%82%a4%e3%83%b3%e3%81%8c%e4%b8%8e%e3%81%88%e3%82%8b%e5%bd%b1%e9%9f%bf\/"},"modified":"2024-10-07T18:27:49","modified_gmt":"2024-10-07T09:27:49","slug":"%e3%83%90%e3%83%8b%e3%82%b7%e3%83%b3%e3%82%b0%e3%83%84%e3%82%a4%e3%83%b3%e3%81%8c%e4%b8%8e%e3%81%88%e3%82%8b%e5%bd%b1%e9%9f%bf","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nippt\/%e3%83%90%e3%83%8b%e3%82%b7%e3%83%b3%e3%82%b0%e3%83%84%e3%82%a4%e3%83%b3%e3%81%8c%e4%b8%8e%e3%81%88%e3%82%8b%e5%bd%b1%e9%9f%bf\/?lang=en","title":{"rendered":"Impact of vanishing twins."},"content":{"rendered":"\n

Vanishing Twin<\/strong> is a phenomenon in which one of the<\/strong> fetuses that starts developing as a twin in the early stages of pregnancy disappears during development<\/strong>. The impact of this phenomenon on prenatal paternity testing should be considered, in particular with regard to<\/p>\n\n\n\n

1. Mixing fetal DNA samples<\/strong><\/h3>\n\n\n\n

When vanishing twins occur, the lost fetal DNA may remain in the mother’s blood or amniotic fluid<\/strong>. In this case, the DNA of the lost fetus may be mixed with the fetal DNA sample taken before birth<\/strong>. This may complicate the DNA test results.<\/p>\n\n\n\n

2. interpretation of expert testimony<\/strong><\/h3>\n\n\n\n
    \n
  • Effects of mixed DNA<\/strong>: if the DNA of the vanishing twin is mixed with the DNA of the remaining fetus, the DNA profile detected may be different from normal. This can lead to<\/strong> ambiguous test results and make it difficult to accurately determine the parent-child relationship<\/strong>.<\/li>\n\n\n\n
  • Occurrence of pseudo diversity<\/strong>: normally, the DNA of a single fetus has genetic material from two parents, but if the<\/strong> DNA profile contains several different genetic information<\/strong> due to the vanishing twin, this can lead to errors in determining parent-child relationships.<\/li>\n<\/ul>\n\n\n\n

    3. Measures and considerations<\/strong><\/h3>\n\n\n\n
      \n
    • High-precision testing methods<\/strong>: the effects of the vanishing twin need to be taken into account in the analysis. High-precision DNA analysis techniques<\/strong> make it easier to distinguish between fetal DNA and vanishing twin DNA.<\/li>\n\n\n\n
    • Need for additional testing<\/strong>: if there is a possibility of a vanishing twin when performing a prenatal paternity test<\/strong>, consider additional testing or retesting at a later date (postnatal DNA testing) to ensure confidence in the results of the test<\/a5> It is important to.<\/li>\n<\/ul>\n\n\n\n

      Summary<\/h2>\n\n\n\n

      Vanishing twins can affect prenatal paternity testing.<\/strong> In particular, the presence of DNA from a vanished twin in a fetal DNA sample can lead to ambiguous results of the analysis<\/strong>. For<\/strong> this reason, high-precision analysis and additional testing is recommended in cases of possible vanishing twins<\/strong>. This is a case that requires expert judgement and careful inspection methods.<\/p>\n","protected":false},"excerpt":{"rendered":"

      Vanishing Twin is a phenomenon in which one of the fetuses that starts developing as …<\/p>\n","protected":false},"author":5,"featured_media":2001,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[39],"class_list":{"0":"post-2686","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-nippt-en","8":"tag-expert-en","9":"article"},"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/posts\/2686","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/comments?post=2686"}],"version-history":[{"count":3,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/posts\/2686\/revisions"}],"predecessor-version":[{"id":5673,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/posts\/2686\/revisions\/5673"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/media\/2001"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/media?parent=2686"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/categories?post=2686"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/tags?post=2686"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}