{"id":6165,"date":"2024-10-18T10:14:07","date_gmt":"2024-10-18T01:14:07","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nippt\/miniseq-limitations-in-str-analysis\/"},"modified":"2024-10-23T12:10:26","modified_gmt":"2024-10-23T03:10:26","slug":"miniseq-limitations-in-str-analysis","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nippt\/miniseq-limitations-in-str-analysis\/?lang=zh-hans","title":{"rendered":"MiniSeq \u65e0\u6cd5\u8bfb\u53d6 STR\u3002"},"content":{"rendered":"\n\n\n\n

\u5176\u4ed6\u516c\u53f8\u4e0d\u652f\u6301 STR<\/a>\uff0c\u56e0\u4e3a\u5b83\u4eec\u662f MiniSeq\uff08\u5c0f\u578b\u6d4b\u5e8f\u4eea\uff09\u3002<\/span><\/p>\n\n\n\n

\u4e3b\u8981\u539f\u56e0\u662f<\/h3>\n\n\n\n
    \n
  1. \u8bfb\u6570\u957f\u5ea6\u9650\u5236\uff1a
    MiniSeq \u652f\u6301\u76f8\u5bf9\u8f83\u77ed\u7684\u8bfb\u6570\u957f\u5ea6\uff08\u6d4b\u5e8f\u8fc7\u7a0b\u4e2d\u8bfb\u53d6\u7684 DNA \u7247\u6bb5\u957f\u5ea6\uff09\uff1b    STR<\/a> \u5206\u6790\u53ef\u80fd\u9700\u8981\u8f83\u957f\u7684\u8bfb\u6570\uff0c\u800c\u8f83\u77ed\u7684\u8bfb\u6570\u53ef\u80fd\u96be\u4ee5\u5206\u6790\u91cd\u590d\u5e8f\u5217\u7684\u786e\u5207\u6570\u91cf\u548c\u987a\u5e8f\u3002\u77ed\u8bfb\u6570\u96be\u4ee5\u5206\u6790\u91cd\u590d\u5e8f\u5217\u7684\u786e\u5207\u6570\u91cf\u548c\u987a\u5e8f\u3002\u77ed\u8bfb\u6570\u53ef\u80fd\u65e0\u6cd5\u51c6\u786e\u8bfb\u53d6\u5e8f\u5217\uff0c\u5c24\u5176\u662f\u5728 STR<\/a> \u533a\u57df\u8f83\u957f\u7684\u60c5\u51b5\u4e0b\u3002<\/li>\n\n\n\n
  2. \u9519\u8bef\u7387\uff1a
    STR<\/a> \u662f\u9ad8\u5ea6\u91cd\u590d\u7684\u5e8f\u5217\uff0c\u800c NGS\uff08\u4e0b\u4e00\u4ee3\u6d4b\u5e8f\uff09\u6280\u672f\u5bf9\u4e8e\u91cd\u590d\u5e8f\u5217\u5c24\u5176\u5bb9\u6613\u51fa\u9519\uff1bMiniSeq \u4e13\u4e3a\u9776\u5411\u6d4b\u5e8f\u800c\u8bbe\u8ba1\uff0c\u5bf9\u5e8f\u5217\u51c6\u786e\u6027\u8981\u6c42\u6781\u9ad8\u3002\u56e0\u6b64\uff0c\u5728\u9700\u8981\u5bf9\u91cd\u590d\u5e8f\u5217\u8fdb\u884c\u5206\u6790\u7684 STR<\/a> \u5206\u6790\u4e2d\uff0c\u9519\u8bef\u7387\u53ef\u80fd\u4f1a\u589e\u52a0\u3002<\/li>\n\n\n\n
  3. \u5206\u6790\u6240\u9700\u7684\u7279\u6b8a\u6587\u5e93\u5236\u5907\uff1a
    STR<\/a> \u5206\u6790\u901a\u5e38\u9700\u8981\u4e13\u95e8\u7684\u6587\u5e93\u5236\u5907\u548c\u5206\u6790\u5de5\u5177\u3002STR<\/a> \u5206\u6790\u6240\u9700\u7684\u5236\u5907\u548c\u5206\u6790\u8f6f\u4ef6\u53ef\u80fd\u4e0d\u5b8c\u5168\u652f\u6301\u3002<\/li>\n\n\n\n
  4. \u6570\u636e\u8f93\u51fa\u7684\u5c40\u9650\u6027\uff1a
    \u4e0e MiSeq \u7b49\u5176\u4ed6\u578b\u53f7\u76f8\u6bd4\uff0cMiniSeq \u7684\u6570\u636e\u541e\u5410\u91cf\u8f83\u4f4e\uff0c\u56e0\u6b64\u5f88\u96be\u751f\u6210\u8db3\u591f\u7684\u6570\u636e\u6765\u8986\u76d6\u5927\u91cf\u91cd\u590d\u5e8f\u5217\u6216\u590d\u6742\u7684     STR<\/a> \u533a\u57df\u3002\u56e0\u6b64\uff0cMiniSeq \u7684\u6027\u80fd\u53ef\u80fd\u4e0d\u591f\u7406\u60f3\u3002<\/li>\n<\/ol>\n\n\n\n\n\n
    \n
    \"NIPPT\u3000\u51fa\u751f\u524dDNA\u9451\u5b9a\u3000\u6b63\u78ba\u6027\"<\/figure><\/div>\n\n\n

    \u5907\u9009\u63d0\u6848\uff1a<\/h3>\n\n\n\n

    \u8981\u83b7\u5f97\u51c6\u786e\u7684 STR<\/a> \u8bfb\u6570\uff0cMiSeq \u6216<\/strong>\u529f\u80fd\u66f4\u5f3a\u7684\u6d4b\u5e8f\u4eea\u66f4\u4e3a\u5408\u9002\u3002\u8fd9\u4e9b\u578b\u53f7\u7684\u6d4b\u5e8f\u4eea\u8bfb\u53d6\u957f\u5ea6\u66f4\u957f\uff0c\u7ea0\u9519\u80fd\u529b\u66f4\u5f3a\uff0c\u53ef\u4ee5\u83b7\u53d6 STR<\/a> \u5206\u6790\u6240\u9700\u7684\u9ad8\u7cbe\u5ea6\u6570\u636e\u3002MiSeq \u7684\u8bfb\u957f\u53ef\u8fbe 600 bps\uff0c\u800c MiniSeq \u8bfb\u957f\u53ea\u6709 300 bps\uff0c\u53ea\u80fd\u8ba1\u7b97 SNP<\/a>\u3002<\/span><\/strong>\u8bb8\u591a\u4f7f\u7528 MiniSeq \u7684\u5b9e\u9a8c\u5ba4\u65e0\u6cd5\u652f\u6301 STR<\/a>\u3002\u4e1c\u4eac\u536b\u751f\u5b9e\u9a8c\u5ba4\u662f\u552f\u4e00\u4e00\u5bb6\u80fd\u591f\u652f\u6301 STR<\/a> \u7684\u5b9e\u9a8c\u5ba4\u3002<\/p>\n\n\n\n

    \u7b80\u800c\u8a00\u4e4b\uff0cMiniSeq \u662f\u4e00\u79cd\u9002\u7528\u4e8e\u76f8\u5bf9\u5c0f\u89c4\u6a21\u9776\u5411\u6d4b\u5e8f\u7684\u4eea\u5668\uff0c\u53ef\u80fd\u65e0\u6cd5\u6ee1\u8db3 STR<\/a> \u5206\u6790\u7b49\u9ad8\u7ea7\u8981\u6c42\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

    \u5176\u4ed6\u516c\u53f8\u4e0d\u652f\u6301 STR\uff0c\u56e0\u4e3a\u5b83\u4eec\u662f MiniSeq\uff08\u5c0f\u578b\u6d4b\u5e8f\u4eea\uff09\u3002 \u4e3b\u8981\u539f\u56e0\u662f \u5907\u9009\u63d0\u6848\uff1a \u8981\u83b7\u5f97\u51c6\u786e\u7684 STR \u8bfb\u6570\uff0cMiSeq \u6216\u529f\u80fd\u66f4\u5f3a\u7684\u6d4b\u5e8f\u4eea\u66f4\u4e3a\u5408\u9002\u3002\u8fd9\u4e9b\u578b\u53f7\u7684…<\/p>\n","protected":false},"author":5,"featured_media":555,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[31],"tags":[81,78,40,66,83,67,68],"class_list":{"0":"post-6165","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-genetic-testing-zh-hans","8":"tag-dna_profiling-zh-hans","9":"tag-dna_test-zh-hans","10":"tag-expert-zh-hans","11":"tag-accuracy-zh-hans","12":"tag-result-zh-hans","13":"tag-genetic_testing-zh-hans","14":"tag-analysis-zh-hans","15":"article"},"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/posts\/6165","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/comments?post=6165"}],"version-history":[{"count":2,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/posts\/6165\/revisions"}],"predecessor-version":[{"id":6169,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/posts\/6165\/revisions\/6169"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/media\/555"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/media?parent=6165"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/categories?post=6165"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nippt\/wp-json\/wp\/v2\/tags?post=6165"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}