{"id":121903,"date":"2026-01-07T18:28:48","date_gmt":"2026-01-07T09:28:48","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?post_type=genetic-diseases&p=121903"},"modified":"2026-03-03T17:39:16","modified_gmt":"2026-03-03T08:39:16","slug":"batten-disease-cln3","status":"publish","type":"genetic-diseases","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/genetic-diseases2\/batten-disease-cln3\/","title":{"rendered":"\u30d0\u30c3\u30c6\u30f3\u75c5\uff08CLN3\u95a2\u9023\uff09"},"content":{"rendered":"\n

\u6982\u8981<\/strong><\/h2>\n\n\n\n

\u30d0\u30c3\u30c6\u30f3\u75c5\uff08CLN3\u95a2\u9023\uff09\u306f\u3001\u795e\u7d4c\u30bb\u30ed\u30a4\u30c9\u30ea\u30dd\u30d5\u30b9\u30c1\u30f3\u75c7\uff08NCL\uff1aneuronal ceroid lipofuscinosis\uff09<\/strong> \u306e\u4e00\u578b\u3067\u3001CLN3\u907a\u4f1d\u5b50\u306e\u75c5\u7684\u5909\u7570<\/strong>\u306b\u3088\u308a\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u795e\u7d4c\u7d30\u80de\u5185\u306b\u30ea\u30dd\u30d5\u30b9\u30c1\u30f3\u69d8\u7269\u8cea\u304c\u84c4\u7a4d<\/strong>\u3057\u3001\u9032\u884c\u6027\u306e\u795e\u7d4c\u5909\u6027\u3092\u304d\u305f\u3059\u907a\u4f1d\u6027\u75be\u60a3\u3067\u3059\u3002\u5178\u578b\u7684\u306b\u306f\u5b66\u7ae5\u671f\u306b\u767a\u75c7<\/strong>\u3057\u3001\u307e\u305a\u8996\u529b\u4f4e\u4e0b\u304c\u51fa\u73fe\u3001\u305d\u306e\u5f8c\u3066\u3093\u304b\u3093\u3001\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u3001\u904b\u52d5\u6a5f\u80fd\u969c\u5bb3\u3078\u3068\u9032\u884c\u3057\u307e\u3059\u3002\u6700\u7d42\u7684\u306b\u306f\u9ad8\u5ea6\u306e\u795e\u7d4c\u969c\u5bb3\u306b\u81f3\u308b\u91cd\u7be4\u306a\u75be\u60a3\u3067\u3059\u3002<\/p>\n\n\n\n

\u75ab\u5b66<\/strong><\/h2>\n\n\n\n

\u30d0\u30c3\u30c6\u30f3\u75c5\uff08CLN3\u578bNCL\uff09\u306f\u4e16\u754c\u7684\u306b\u7a00\u3067\u3001\u767a\u75c7\u983b\u5ea6\u306f\u7d041\/100,000\u51fa\u751f<\/strong>\u3068\u63a8\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5317\u6b27\u3084\u6b27\u7c73\u3067\u6bd4\u8f03\u7684\u591a\u304f\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u65e5\u672c\u3067\u306f\u975e\u5e38\u306b\u307e\u308c\u3067\u3059\u3002\u7537\u5973\u5dee\u306f\u306a\u304f\u3001\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\u907a\u4f1d<\/strong>\u3068\u3057\u3066\u767a\u75c7\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u539f\u56e0<\/strong><\/h2>\n\n\n\n

\u75c5\u56e0<\/strong><\/h3>\n\n\n\n

\u539f\u56e0\u306f CLN3\u907a\u4f1d\u5b50\u306e\u75c5\u7684\u5909\u7570<\/strong> \u3067\u3059\u3002CLN3\u306f\u7d30\u80de\u5185\u5c0f\u80de\u30fb\u30ea\u30bd\u30bd\u30fc\u30e0\u95a2\u9023\u819c\u30bf\u30f3\u30d1\u30af\u3092\u30b3\u30fc\u30c9\u3057\u3001\u7d30\u80de\u5185\u306e\u8001\u5ec3\u7269\u51e6\u7406\u30fb\u30ea\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u6a5f\u69cb\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u5909\u7570\u306b\u3088\u308a\u5206\u89e3\u3055\u308c\u308b\u3079\u304d\u7269\u8cea\u304c\u795e\u7d4c\u7d30\u80de\u5185\u306b\u84c4\u7a4d\u3057\u3001\u7d30\u80de\u6b7b\u3068\u795e\u7d4c\u5909\u6027\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

\u907a\u4f1d\u5f62\u5f0f<\/strong><\/h3>\n\n\n\n

\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\u907a\u4f1d<\/strong>\u3067\u3001\u4e21\u89aa\u304b\u3089\u305d\u308c\u305e\u308c\u75c5\u7684\u5909\u7570\u3092\u53d7\u3051\u7d99\u3044\u3060\u5834\u5408\u306b\u767a\u75c7\u3057\u307e\u3059\u3002\u4fdd\u56e0\u8005\u306f\u901a\u5e38\u7121\u75c7\u72b6\u3067\u3059\u3002<\/p>\n\n\n\n

\u75c7\u72b6<\/strong><\/h2>\n\n\n\n

\u4e3b\u306a\u75c7\u72b6\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n

    \n
  • \u9032\u884c\u6027\u306e\u8996\u529b\u4f4e\u4e0b\u30fb\u5931\u660e<\/strong>\uff08\u521d\u767a\u75c7\u72b6\u306e\u3053\u3068\u304c\u591a\u3044\uff09<\/li>\n\n\n\n
  • \u3066\u3093\u304b\u3093\u767a\u4f5c<\/strong><\/li>\n\n\n\n
  • \u5b66\u7fd2\u80fd\u529b\u30fb\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b<\/strong><\/li>\n\n\n\n
  • \u904b\u52d5\u5931\u8abf\u3001\u6b69\u884c\u969c\u5bb3\u3001\u30b8\u30b9\u30c8\u30cb\u30a2<\/li>\n\n\n\n
  • \u8a00\u8a9e\u969c\u5bb3\u3001\u884c\u52d5\u5909\u5316<\/li>\n\n\n\n
  • \u6700\u7d42\u7684\u306b\u91cd\u5ea6\u306e\u795e\u7d4c\u969c\u5bb3\u3001\u5bdd\u305f\u304d\u308a\u72b6\u614b\u306b\u9032\u884c<\/li>\n<\/ul>\n\n\n\n

    \u767a\u75c7\u306f\u591a\u304f\u304c5\u301c10\u6b73\u9803<\/strong>\u3067\u300110\u4ee3\u5f8c\u534a\u301c20\u4ee3\u524d\u534a\u3067\u91cd\u7be4\u306a\u72b6\u614b\u3068\u306a\u308b\u3053\u3068\u304c\u591a\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

    \u8a3a\u65ad<\/strong><\/h2>\n\n\n\n

    \u8a3a\u65ad\u306f\u4ee5\u4e0b\u3092\u7dcf\u5408\u3057\u3066\u884c\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

      \n
    1. \u81e8\u5e8a\u75c7\u72b6<\/strong>\uff08\u8996\u529b\u4f4e\u4e0b\uff0b\u3066\u3093\u304b\u3093\uff0b\u767a\u9054\u9000\u884c\uff09<\/li>\n\n\n\n
    2. \u773c\u79d1\u691c\u67fb<\/strong>\uff1a\u7db2\u819c\u5909\u6027<\/li>\n\n\n\n
    3. \u8133\u753b\u50cf\uff08MRI\uff09<\/strong>\uff1a\u5927\u8133\u30fb\u5c0f\u8133\u840e\u7e2e<\/li>\n\n\n\n
    4. \u907a\u4f1d\u5b50\u691c\u67fb<\/strong>\uff1aCLN3\u907a\u4f1d\u5b50\u306e\u75c5\u7684\u5909\u7570\u540c\u5b9a<\/strong>\u306b\u3088\u308b\u78ba\u5b9a\u8a3a\u65ad<\/li>\n\n\n\n
    5. \u5fc5\u8981\u306b\u5fdc\u3058\u3066\u76ae\u819a\u751f\u691c\u30fb\u96fb\u5b50\u9855\u5fae\u93e1\u3067\u84c4\u7a4d\u7269\u8cea\u3092\u78ba\u8a8d<\/li>\n<\/ol>\n\n\n\n

      \u6cbb\u7642<\/strong><\/h2>\n\n\n\n

      \u73fe\u6642\u70b9\u3067\u6839\u6cbb\u7642\u6cd5\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u6cbb\u7642\u306f\u652f\u6301\u7642\u6cd5\u3068\u75c7\u72b6\u7de9\u548c<\/strong>\u304c\u4e2d\u5fc3\u3067\u3059\u3002<\/p>\n\n\n\n

        \n
      • \u6297\u3066\u3093\u304b\u3093\u85ac\u306b\u3088\u308b\u767a\u4f5c\u7ba1\u7406<\/li>\n\n\n\n
      • \u7406\u5b66\u7642\u6cd5\u30fb\u4f5c\u696d\u7642\u6cd5<\/li>\n\n\n\n
      • \u8996\u899a\u88dc\u52a9\u30fb\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u652f\u63f4<\/li>\n\n\n\n
      • \u6804\u990a\u7ba1\u7406\u3001\u56a5\u4e0b\u30fb\u547c\u5438\u7ba1\u7406<\/li>\n\n\n\n
      • \u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0<\/li>\n<\/ul>\n\n\n\n

        \u73fe\u5728\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\u30fb\u5206\u5b50\u6a19\u7684\u6cbb\u7642<\/strong>\u306e\u7814\u7a76\u304c\u9032\u884c\u4e2d\u3067\u3059\u304c\u3001\u81e8\u5e8a\u6a19\u6e96\u6cbb\u7642\u306b\u306f\u81f3\u3063\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n

        \u53c2\u8003\u6587\u732e\u5143<\/strong><\/h2>\n\n\n\n
          \n
        1. GeneReviews\u00ae<\/strong>: Neuronal Ceroid Lipofuscinosis 3<\/em> \u2014 CLN3\u578bNCL\u306e\u7dcf\u8aac\u3002<\/li>\n\n\n\n
        2. MedlinePlus Genetics<\/strong>: CLN3 disease<\/em> \u2014 \u75c5\u56e0\u3068\u907a\u4f1d\u5f62\u5f0f\u3002<\/li>\n\n\n\n
        3. Orphanet<\/strong>: Neuronal ceroid lipofuscinosis, CLN3<\/em> \u2014 \u75ab\u5b66\u3068\u75be\u60a3\u6982\u8981\u3002<\/li>\n\n\n\n
        4. NORD (National Organization for Rare Disorders)<\/strong>: Batten disease (juvenile form)<\/em> \u2014 \u81e8\u5e8a\u50cf\u30fb\u7d4c\u904e\u3002<\/li>\n\n\n\n
        5. Mole SE, et al. Lancet Neurology<\/em> 2019 \u2014 NCL\u7dcf\u8aac\u30ec\u30d3\u30e5\u30fc\u3002<\/li>\n<\/ol>\n","protected":false},"featured_media":0,"menu_order":0,"template":"page_gd.php","class_list":["post-121903","genetic-diseases","type-genetic-diseases","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/121903","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/genetic-diseases"}],"version-history":[{"count":4,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/121903\/revisions"}],"predecessor-version":[{"id":125307,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/121903\/revisions\/125307"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=121903"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}