{"id":121962,"date":"2026-01-08T11:21:38","date_gmt":"2026-01-08T02:21:38","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?post_type=genetic-diseases&p=121962"},"modified":"2026-03-03T16:37:55","modified_gmt":"2026-03-03T07:37:55","slug":"mucopolysaccharidosis-type-ix-hyal1","status":"publish","type":"genetic-diseases","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/genetic-diseases2\/mucopolysaccharidosis-type-ix-hyal1\/","title":{"rendered":"\u30e9\u30a4\u30bd\u30be\u30fc\u30e0\u75c5\uff08\u30e0\u30b3\u591a\u7cd6\u75c7IX\u578b\u3001\u30d2\u30a2\u30eb\u30ed\u30cb\u30c0\u30fc\u30bc\u6b20\u640d\u75c7\uff09"},"content":{"rendered":"\n

\u6982\u8981<\/strong><\/h2>\n\n\n\n

\u30e0\u30b3\u591a\u7cd6\u75c7IX\u578b\uff08Mucopolysaccharidosis type IX\uff1aMPS IX\uff09\u306f\u3001\u30d2\u30a2\u30eb\u30ed\u30cb\u30c0\u30fc\u30bc1\uff08HYAL1\uff09\u306e\u6b20\u640d\u306b\u3088\u308a\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u304c\u5206\u89e3\u3055\u308c\u305a\u306b\u7d44\u7e54\u5185\u306b\u84c4\u7a4d\u3059\u308b\u6975\u3081\u3066\u7a00\u306a\u30e9\u30a4\u30bd\u30be\u30fc\u30e0\u84c4\u7a4d\u75c7\u3067\u3059\u3002\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u306f\u95a2\u7bc0\u3001\u76ae\u819a\u3001\u785d\u5b50\u4f53\u3001\u8840\u7ba1\u58c1\u306a\u3069\u306b\u5e83\u304f\u5b58\u5728\u3059\u308b\u30b0\u30ea\u30b3\u30b5\u30df\u30ce\u30b0\u30ea\u30ab\u30f3\u3067\u3042\u308a\u3001\u305d\u306e\u4ee3\u8b1d\u969c\u5bb3\u306b\u3088\u308a\u95a2\u7bc0\u816b\u8139\u3001\u95a2\u7bc0\u53ef\u52d5\u57df\u5236\u9650\u3001\u6ed1\u819c\u80a5\u539a\u306a\u3069\u304c\u4e3b\u75c7\u72b6\u3068\u306a\u308a\u307e\u3059\u3002\u53e4\u5178\u7684\u306a\u30e0\u30b3\u591a\u7cd6\u75c7\uff08I\u578b\u301cVII\u578b\uff09\u3068\u7570\u306a\u308a\u3001\u4e2d\u67a2\u795e\u7d4c\u969c\u5bb3\u3084\u91cd\u5ea6\u306e\u81d3\u5668\u969c\u5bb3\u306f\u6bd4\u8f03\u7684\u8efd\u5ea6\u3067\u3042\u308b\u70b9\u304c\u7279\u5fb4\u3067\u3059\u3002<\/p>\n\n\n\n

MPS IX\u306f1996\u5e74\u306b\u521d\u3081\u3066\u5831\u544a\u3055\u308c\u3001\u4e16\u754c\u3067\u3082\u5831\u544a\u75c7\u4f8b\u306f\u975e\u5e38\u306b\u9650\u3089\u308c\u3066\u3044\u307e\u3059\u3002(PMC)<\/p>\n\n\n\n

\u75ab\u5b66<\/strong><\/h2>\n\n\n\n

MPS IX\u306f\u6700\u3082\u7a00\u306a\u30e0\u30b3\u591a\u7cd6\u75c7\u578b\u306e\u4e00\u3064\u3067\u3001\u5831\u544a\u4f8b\u306f\u4e16\u754c\u306720\u4f8b\u672a\u6e80\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6b63\u78ba\u306a\u6709\u75c5\u7387\u306f\u4e0d\u660e\u3067\u3059\u304c\u3001\u6975\u3081\u3066\u7a00\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002(Orphanet)<\/p>\n\n\n\n

\u539f\u56e0<\/strong><\/h2>\n\n\n\n

\u672c\u75be\u60a3\u306fHYAL1\u907a\u4f1d\u5b50\u306e\u4e21\u30a2\u30ec\u30eb\u75c5\u7684\u5909\u7570\u306b\u3088\u308a\u767a\u75c7\u3057\u307e\u3059\u3002HYAL1\u907a\u4f1d\u5b50\u306f\u30d2\u30c83\u756a\u67d3\u8272\u4f53\uff083p21\uff09\u306b\u4f4d\u7f6e\u3057\u3001\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u5206\u89e3\u306b\u95a2\u4e0e\u3059\u308b\u30ea\u30bd\u30bd\u30fc\u30e0\u9175\u7d20\u3092\u30b3\u30fc\u30c9\u3057\u307e\u3059\u3002\u3053\u306e\u9175\u7d20\u304c\u6b20\u640d\u3059\u308b\u3068\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u304c\u5206\u89e3\u3055\u308c\u305a\u306b\u84c4\u7a4d\u3057\u307e\u3059\u3002(\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af)<\/p>\n\n\n\n

\u907a\u4f1d\u5f62\u5f0f\u306f\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\u907a\u4f1d\u3067\u3059\u3002<\/p>\n\n\n\n

\u75c7\u72b6<\/strong><\/h2>\n\n\n\n

\u95a2\u7bc0<\/strong><\/p>\n\n\n\n

    \n
  • \u53cd\u5fa9\u6027\u95a2\u7bc0\u816b\u8139<\/li>\n\n\n\n
  • \u6ed1\u819c\u80a5\u539a<\/li>\n\n\n\n
  • \u95a2\u7bc0\u62d8\u7e2e<\/li>\n\n\n\n
  • \u904b\u52d5\u5236\u9650<\/li>\n<\/ul>\n\n\n\n

    \u9aa8\u683c<\/strong><\/p>\n\n\n\n

      \n
    • \u8efd\u5ea6\u306e\u9aa8\u7570\u5f62\u6210<\/li>\n\n\n\n
    • \u6210\u9577\u969c\u5bb3\uff08\u8efd\u5ea6\uff09<\/li>\n<\/ul>\n\n\n\n

      \u305d\u306e\u4ed6<\/strong><\/p>\n\n\n\n

        \n
      • \u76ae\u4e0b\u7d50\u7bc0<\/li>\n\n\n\n
      • \u89d2\u819c\u6df7\u6fc1\uff08\u8efd\u5ea6\uff09<\/li>\n\n\n\n
      • \u53cd\u5fa9\u6027\u6ed1\u819c\u708e<\/li>\n<\/ul>\n\n\n\n

        \u77e5\u7684\u767a\u9054\u306f\u6b63\u5e38\u3067\u3059\u3002<\/p>\n\n\n\n

        \u8a3a\u65ad<\/strong><\/h2>\n\n\n\n
          \n
        1. \u5c3f\u4e2d\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u9ad8\u5024<\/li>\n\n\n\n
        2. \u95a2\u7bc0MRI\u3067\u6ed1\u819c\u80a5\u539a<\/li>\n\n\n\n
        3. HYAL1\u9175\u7d20\u6d3b\u6027\u4f4e\u4e0b<\/li>\n\n\n\n
        4. \u907a\u4f1d\u5b50\u8a3a\u65ad\uff08HYAL1\u89e3\u6790\uff09(PMC)<\/li>\n<\/ol>\n\n\n\n

          \u6cbb\u7642<\/strong><\/h2>\n\n\n\n
            \n
          • \u5bfe\u75c7\u7642\u6cd5\uff08\u93ae\u75db\u3001\u6297\u708e\u75c7\uff09<\/li>\n\n\n\n
          • \u6574\u5f62\u5916\u79d1\u7684\u7ba1\u7406<\/li>\n\n\n\n
          • \u7406\u5b66\u7642\u6cd5<\/li>\n\n\n\n
          • \u514d\u75ab\u6291\u5236\u85ac\uff08\u6ed1\u819c\u708e\u306b\u5bfe\u3057\u3066\u4e00\u90e8\u6709\u52b9\u4f8b\u3042\u308a\uff09<\/li>\n<\/ul>\n\n\n\n

            \u9175\u7d20\u88dc\u5145\u7642\u6cd5\u3084\u907a\u4f1d\u5b50\u6cbb\u7642\u306f\u73fe\u6642\u70b9\u3067\u306f\u78ba\u7acb\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n

            \u53c2\u8003\u6587\u732e<\/strong><\/h2>\n\n\n\n

            Mucopolysaccharidosis Type IX \u2014 GeneReviews, PubMed Central.(PMC)
            Natowicz MR et al. Mucopolysaccharidosis type IX. N Engl J Med. 1996.(NEJM)
            MPS IX \u2014 Orphanet Rare Disease Database.(Orphanet)
            HYAL1 \u2014 Malacards Gene\/Disease Database.(malacards.org)<\/p>\n","protected":false},"featured_media":0,"menu_order":0,"template":"page_gd.php","class_list":["post-121962","genetic-diseases","type-genetic-diseases","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/121962","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/genetic-diseases"}],"version-history":[{"count":3,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/121962\/revisions"}],"predecessor-version":[{"id":125293,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/121962\/revisions\/125293"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=121962"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}