{"id":122118,"date":"2026-01-08T17:50:53","date_gmt":"2026-01-08T08:50:53","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?post_type=genetic-diseases&p=122118"},"modified":"2026-03-03T12:43:33","modified_gmt":"2026-03-03T03:43:33","slug":"zellweger-spectrum-disorders-pex10-related-pex10","status":"publish","type":"genetic-diseases","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/genetic-diseases2\/zellweger-spectrum-disorders-pex10-related-pex10\/","title":{"rendered":"\u30bc\u30eb\u30a6\u30a3\u30ac\u30fc\u30fb\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u969c\u5bb3\uff08PEX10\u95a2\u9023\uff09\u3001PEX10"},"content":{"rendered":"\n

\u6982\u8981<\/strong><\/h2>\n\n\n\n

\u30bc\u30eb\u30a6\u30a3\u30ac\u30fc\u30fb\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u969c\u5bb3\uff08Zellweger Spectrum Disorders\uff1aZSD\uff09\u306f\u3001\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u306e\u5f62\u6210\u304a\u3088\u3073\u6a5f\u80fd\u7570\u5e38\u306b\u3088\u308a\u751f\u3058\u308b\u5148\u5929\u6027\u4ee3\u8b1d\u75be\u60a3\u7fa4\u3067\u3001\u91cd\u75c7\u306e\u65b0\u751f\u5150\u578b\u304b\u3089\u8efd\u75c7\u306e\u6210\u4eba\u767a\u75c7\u578b\u307e\u3067\u5e45\u5e83\u3044\u81e8\u5e8a\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u3092\u793a\u3057\u307e\u3059\u3002PEX10\u306f\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u306b\u95a2\u4e0e\u3057\u3001\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u9175\u7d20\u8f38\u9001\u306b\u5fc5\u9808\u306aE3\u30e6\u30d3\u30ad\u30c1\u30f3\u30ea\u30ac\u30fc\u30bc\u6d3b\u6027\u3092\u62c5\u3046\u56e0\u5b50\u3067\u3059\u3002\u3053\u306e\u6a5f\u80fd\u304c\u969c\u5bb3\u3055\u308c\u308b\u3068\u3001\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u5185\u3078\u306e\u9175\u7d20\u53d6\u308a\u8fbc\u307f\u304c\u963b\u5bb3\u3055\u308c\u3001\u8102\u80aa\u9178\u4ee3\u8b1d\u3001\u80c6\u6c41\u9178\u5408\u6210\u3001\u30d7\u30e9\u30b9\u30de\u30ed\u30fc\u30b2\u30f3\u5408\u6210\u306a\u3069\u304c\u7834\u7dbb\u3057\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u8d85\u9577\u9396\u8102\u80aa\u9178\uff08VLCFA\uff09\u306e\u84c4\u7a4d\u3001\u8133\u767d\u8cea\u5f62\u6210\u969c\u5bb3\u3001\u809d\u969c\u5bb3\u306a\u3069\u591a\u81d3\u5668\u969c\u5bb3\u304c\u751f\u3058\u307e\u3059\u3002(PMC)<\/p>\n\n\n\n

\u75ab\u5b66<\/strong><\/h2>\n\n\n\n

ZSD\u5168\u4f53\u306e\u6709\u75c5\u7387\u306f\u51fa\u751f5\u4e07\u301c10\u4e07\u4eba\u306b1\u4eba\u3068\u63a8\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002PEX10\u95a2\u9023\u578b\u306f\u6bd4\u8f03\u7684\u7a00\u3067\u3059\u304c\u3001\u4e16\u754c\u4e2d\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002(Orphanet)<\/p>\n\n\n\n

\u539f\u56e0<\/strong><\/h2>\n\n\n\n

\u672c\u75be\u60a3\u306fPEX10\u907a\u4f1d\u5b50\u306e\u4e21\u30a2\u30ec\u30eb\u75c5\u7684\u5909\u7570\u306b\u3088\u308a\u767a\u75c7\u3057\u307e\u3059\u3002PEX10\u306f\u30d2\u30c81\u756a\u67d3\u8272\u4f53\uff081p36<\/a>\uff09\u306b\u4f4d\u7f6e\u3057\u3001\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u54c1\u8cea\u7ba1\u7406\u306b\u95a2\u4e0e\u3057\u307e\u3059\u3002(\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af)<\/p>\n\n\n\n

\u907a\u4f1d\u5f62\u5f0f\u306f\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\u907a\u4f1d\u3067\u3059\u3002<\/p>\n\n\n\n

\u75c7\u72b6<\/strong><\/h2>\n\n\n\n

\u795e\u7d4c\u7cfb<\/strong><\/h3>\n\n\n\n
    \n
  • \u7b4b\u7dca\u5f35\u4f4e\u4e0b<\/li>\n\n\n\n
  • \u767a\u9054\u9045\u6ede<\/li>\n\n\n\n
  • \u3051\u3044\u308c\u3093<\/li>\n\n\n\n
  • \u96e3\u8074\u30fb\u8996\u899a\u969c\u5bb3<\/li>\n<\/ul>\n\n\n\n

    \u809d\u80c6\u9053\u7cfb<\/strong><\/h3>\n\n\n\n
      \n
    • \u809d\u816b\u5927<\/li>\n\n\n\n
    • \u80c6\u6c41\u3046\u3063\u6ede<\/li>\n<\/ul>\n\n\n\n

      \u9aa8\u683c\u30fb\u9854\u8c8c<\/strong><\/h3>\n\n\n\n
        \n
      • \u524d\u982d\u7a81\u51fa<\/li>\n\n\n\n
      • \u9ad8\u53e3\u84cb<\/li>\n\n\n\n
      • \u95a2\u7bc0\u62d8\u7e2e<\/li>\n<\/ul>\n\n\n\n

        \u8a3a\u65ad<\/strong><\/h2>\n\n\n\n
          \n
        1. \u8840\u4e2dVLCFA\u9ad8\u5024<\/li>\n\n\n\n
        2. \u30d7\u30e9\u30b9\u30de\u30ed\u30fc\u30b2\u30f3\u4f4e\u4e0b<\/li>\n\n\n\n
        3. MRI\u3067\u767d\u8cea\u5f62\u6210\u7570\u5e38<\/li>\n\n\n\n
        4. \u907a\u4f1d\u5b50\u8a3a\u65ad\uff08PEX10\u89e3\u6790\uff09(PMC)<\/li>\n<\/ol>\n\n\n\n

          \u6cbb\u7642<\/strong><\/h2>\n\n\n\n
            \n
          • \u5bfe\u75c7\u7642\u6cd5\u4e2d\u5fc3<\/li>\n\n\n\n
          • \u6804\u990a\u7ba1\u7406<\/li>\n\n\n\n
          • \u767a\u9054\u652f\u63f4<\/li>\n\n\n\n
          • \u3066\u3093\u304b\u3093\u7ba1\u7406<\/li>\n\n\n\n
          • \u611f\u899a\u88dc\u52a9<\/li>\n<\/ul>\n\n\n\n

            \u53c2\u8003\u6587\u732e<\/strong><\/h2>\n\n\n\n

            Zellweger Spectrum Disorders \u2014 GeneReviews, PubMed Central.(PMC)
            Braverman NE et al. Zellweger spectrum disorders. Nat Rev Dis Primers. 2016.(Nature Reviews)
            Zellweger Spectrum Disorders \u2014 Orphanet Rare Disease Database.(Orphanet)
            PEX10 \u2014 Malacards Gene\/Disease Database.(malacards.org)<\/p>\n\n\n\n

            <\/p>\n","protected":false},"featured_media":0,"menu_order":0,"template":"page_gd.php","class_list":["post-122118","genetic-diseases","type-genetic-diseases","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/122118","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/genetic-diseases"}],"version-history":[{"count":2,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/122118\/revisions"}],"predecessor-version":[{"id":125251,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/122118\/revisions\/125251"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=122118"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}