{"id":136699,"date":"2026-09-08T12:23:13","date_gmt":"2026-09-08T03:23:13","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?post_type=genetic-diseases&#038;p=136699"},"modified":"2026-09-08T12:23:13","modified_gmt":"2026-09-08T03:23:13","slug":"cerebellar-ataxia-mental-retardation-and-dysequilibriumsyndrome-1-vldlr","status":"publish","type":"genetic-diseases","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/genetic-diseases2\/cerebellar-ataxia-mental-retardation-and-dysequilibriumsyndrome-1-vldlr\/","title":{"rendered":"\u5c0f\u8133\u5931\u8abf\u30fb\u77e5\u7684\u969c\u5bb3\u30fb\u5e73\u8861\u969c\u5bb3\u75c7\u5019\u7fa41\u578b"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">\u6982\u8981<\/h2>\n\n\n\n<p>\u5c0f\u8133\u5931\u8abf\u30fb<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u30fb\u5e73\u8861\u969c\u5bb3\u75c7\u5019\u7fa41\u578b\uff08VLDLR\u95a2\u9023\u5c0f\u8133\u4f4e\u5f62\u6210\uff0f\u30c7\u30a3\u30b9\u30a8\u30af\u30a3\u30ea\u30d6\u30ea\u30a6\u30e0\u75c7\u5019\u7fa4\uff09\u306f\u3001\u751f\u307e\u308c\u3064\u304d\u5c0f\u8133\u304c\u5c0f\u3055\u3044\u305f\u3081\u306b\u3001\u6b69\u3051\u308b\u3088\u3046\u306b\u306a\u308b\u306e\u304c\u9045\u308c\u3001\u4f53\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u53d6\u308a\u306b\u304f\u3044\u75c5\u6c17\u3067\u3059\u3002\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\uff08\u52a3\u6027\uff09\u907a\u4f1d\u306e\u5f62\u5f0f\u3092\u3068\u308a\u3001<strong>VLDLR<\/strong> \u907a\u4f1d\u5b50\u306e\u5909\u5316\u304c\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p><strong>\u56db\u3064\u3070\u3044\u3067\u306f\u306a\u304f\u3001\u624b\u3068\u8db3\u3067\u6b69\u304f\uff08\u56db\u8db3\u6b69\u884c\uff09<\/strong>\u65b9\u304c\u3044\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3001\u6ce8\u76ee\u3055\u308c\u305f\u75c5\u6c17\u3067\u3059\u3002\u8fd1\u89aa\u5a5a\u306e\u3042\u308b\u96c6\u56e3\uff08\u30d5\u30c3\u30bf\u30fc\u6d3e\u3001\u4e2d\u6771\u306a\u3069\uff09\u3067\u306e\u5831\u544a\u304c\u591a\u304f\u307f\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u539f\u56e0<\/h2>\n\n\n\n<p><strong>VLDLR<\/strong> \u907a\u4f1d\u5b50\u306f\u3001\u8d85\u4f4e\u6bd4\u91cd\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u53d7\u5bb9\u4f53\u306e\u8a2d\u8a08\u56f3\u3067\u3059\u3002\u3053\u306e\u53d7\u5bb9\u4f53\u306f\u3001\u8102\u8cea\u306e\u53d6\u308a\u8fbc\u307f\u3060\u3051\u3067\u306a\u304f\u3001<strong>\u8133\u306e\u767a\u751f\u306b\u304a\u3044\u3066\u30ea\u30fc\u30ea\u30f3\u3068\u3044\u3046\u7269\u8cea\u306e\u4fe1\u53f7\u3092\u53d7\u3051\u53d6\u308a\u3001\u795e\u7d4c\u7d30\u80de\u3092\u6b63\u3057\u3044\u5834\u6240\u3078\u5c0e\u304f<\/strong>\u5f79\u76ee\u3092\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u53d7\u5bb9\u4f53\u304c\u306f\u305f\u3089\u304b\u306a\u3044\u3068\u3001\u795e\u7d4c\u7d30\u80de\u306e\u79fb\u52d5\u304c\u3046\u307e\u304f\u3044\u304b\u305a\u3001\u5c0f\u8133\u3068\u5927\u8133\u306e\u4e00\u90e8\u304c\u6b63\u3057\u304f\u4f5c\u3089\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u75c7\u72b6<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8457\u3057\u3044\u904b\u52d5\u767a\u9054\u306e\u9045\u308c<\/strong>\uff08\u6b69\u884c\u306e\u7372\u5f97\u304c\u9045\u308c\u308b\u3001\u307e\u305f\u306f\u7372\u5f97\u3067\u304d\u306a\u3044\uff09<\/li>\n\n\n\n<li><strong>\u4f53\u306e\u30d0\u30e9\u30f3\u30b9\u304c\u53d6\u308a\u306b\u304f\u3044\uff08\u5931\u8abf\uff09<\/strong><\/li>\n\n\n\n<li>\u4e2d\u7b49\u5ea6\u301c\u91cd\u5ea6\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a><\/li>\n\n\n\n<li>\u3051\u3044\u308c\u3093<\/li>\n\n\n\n<li>\u4f4e\u8eab\u9577<\/li>\n\n\n\n<li>\u659c\u8996\u3001\u773c\u632f<\/li>\n\n\n\n<li><strong>\u4e00\u90e8\u306e\u65b9\u3067\u56db\u8db3\u6b69\u884c\uff08\u624b\u3068\u8db3\u3092\u4f7f\u3063\u305f\u6b69\u884c\uff09\u304c\u307f\u3089\u308c\u307e\u3059<\/strong><\/li>\n\n\n\n<li>MRI\u3067\u306e<strong>\u5c0f\u8133\u4f4e\u5f62\u6210\uff08\u3068\u304f\u306b\u866b\u90e8\uff09\u3068\u3001\u5927\u8133\u76ae\u8cea\u306e\u5358\u7d14\u5316\u3057\u305f\u8133\u56de<\/strong><\/li>\n\n\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">\u691c\u67fb\u30fb\u8a3a\u65ad<\/h2>\n\n\n\n<p>\u751f\u307e\u308c\u3064\u304d\u306e\u904b\u52d5\u767a\u9054\u306e\u9045\u308c\u3068\u5931\u8abf\u304b\u3089\u7591\u3044\u3001\u982d\u90e8MRI\u3067\u5c0f\u8133\u4f4e\u5f62\u6210\u3068\u5927\u8133\u76ae\u8cea\u306e\u8133\u56de\u306e\u5358\u7d14\u5316\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002<strong>VLDLR<\/strong> \u907a\u4f1d\u5b50\u306e\u89e3\u6790\u306b\u3088\u3063\u3066\u78ba\u5b9a\u3057\u307e\u3059\u3002\u4f3c\u305f\u6240\u898b\u3092\u793a\u3059\u4ed6\u306e\u75be\u60a3\uff08\u30ea\u30fc\u30ea\u30f3\uff08RELN\uff09\u95a2\u9023\u3001\u30b8\u30e5\u30d9\u30fc\u30eb\u75c7\u5019\u7fa4\u306a\u3069\uff09\u3068\u306e\u533a\u5225\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u6cbb\u7642<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6839\u672c\u7684\u306b\u6cbb\u3059\u65b9\u6cd5\u306f\u78ba\u7acb\u3057\u3066\u3044\u307e\u305b\u3093<\/strong><\/li>\n\n\n\n<li>\u7406\u5b66\u7642\u6cd5\u30fb\u4f5c\u696d\u7642\u6cd5\u306b\u3088\u308b\u904b\u52d5\u6a5f\u80fd\u306e\u652f\u63f4<\/li>\n\n\n\n<li>\u6b69\u884c\u88dc\u52a9\u5177\u3001\u88c5\u5177<\/li>\n\n\n\n<li>\u3051\u3044\u308c\u3093\u306b\u5bfe\u3059\u308b\u6297\u3066\u3093\u304b\u3093\u85ac<\/li>\n\n\n\n<li>\u7642\u80b2\u30fb\u6559\u80b2\u9762\u3067\u306e\u652f\u63f4\u3001\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u306e\u652f\u63f4<\/li>\n\n\n\n<li>\u5b9a\u671f\u7684\u306a\u767a\u9054\u306e\u8a55\u4fa1<\/li>\n\n\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">\u3053\u306e\u75be\u60a3\u306f\u691c\u67fb\u3067\u308f\u304b\u308a\u307e\u3059<\/h2>\n\n\n\n<p>\u3053\u306e\u75be\u60a3\u306f\u3001\u539f\u56e0\u3068\u306a\u308b <strong>VLDLR<\/strong> \u907a\u4f1d\u5b50\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u767a\u75c7\u524d\u3084\u51fa\u751f\u524d\u306b\u898b\u3064\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30afNIPT\u3067\u306f\u6b21\u306e2\u3064\u306e\u691c\u67fb\u3092\u3054\u7528\u610f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u3092\u7528\u3044\u305f\u691c\u67fb\uff081,200\u7a2e\u985e\u4ee5\u4e0a\uff09<\/h3>\n\n\n\n<p>\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u306f\u3001\u907a\u4f1d\u5b50\u306e\u3046\u3061\u305f\u3093\u3071\u304f\u8cea\u306e\u8a2d\u8a08\u56f3\u306b\u3042\u305f\u308b\u90e8\u5206\uff08\u30a8\u30af\u30bd\u30f3\uff09\u3092\u307e\u3068\u3081\u3066\u8aad\u307f\u53d6\u308b\u691c\u67fb\u3067\u3059\u3002\u3053\u306e\u89e3\u6790\u3092\u884c\u3063\u305f\u3046\u3048\u3067\u3001<strong>VLDLR<\/strong> \u907a\u4f1d\u5b50\u3092\u542b\u3080<strong>1,200\u7a2e\u985e\u4ee5\u4e0a<\/strong>\u306e\u907a\u4f1d\u5b50\u3092\u5bfe\u8c61\u306b\u8abf\u3079\u3001<strong>\u3053\u306e\u75be\u60a3\u306e\u539f\u56e0\u3068\u306a\u308b\u5909\u5316\u3092\u691c\u51fa\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059<\/strong>\u3002\u56fd\u5185\u306e\u691c\u67fb\u6240\u3067\u884c\u3044\u3001\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f5\u9031\u9593\u301c7\u9031\u9593\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u30ad\u30e3\u30ea\u30a2\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c6\u30b9\u30c8\uff08228\u7a2e\u985e\uff09<\/h3>\n\n\n\n<p>\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\uff08\u52a3\u6027\uff09\u907a\u4f1d\u306e\u75be\u60a3\u306f\u3001\u3054\u4e21\u89aa\u304c\u3069\u3061\u3089\u3082\u75c7\u72b6\u306e\u306a\u3044\u300c\u30ad\u30e3\u30ea\u30a2\uff08\u4fdd\u56e0\u8005\uff09\u300d\u3067\u3042\u308b\u3068\u304d\u306b\u3001<strong>4\u5206\u306e1\u306e\u78ba\u7387<\/strong>\u3067\u304a\u5b50\u3055\u307e\u304c\u767a\u75c7\u3057\u307e\u3059\u3002\u30ad\u30e3\u30ea\u30a2\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c6\u30b9\u30c8\u3067\u306f\u3001\u3054\u592b\u5a66\u304c\u3053\u306e\u75be\u60a3\u306e\u30ad\u30e3\u30ea\u30a2\u304b\u3069\u3046\u304b\u3092\u982c\u306e\u5185\u5074\u306e\u7c98\u819c\u304b\u3089\u8abf\u3079\u3001<strong>\u304a\u5b50\u3055\u307e\u306b\u53d7\u3051\u7d99\u304c\u308c\u308b\u53ef\u80fd\u6027\u3092\u3001\u598a\u5a20\u524d\u3084\u51fa\u751f\u524d\u306b\u4e88\u6e2c\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059<\/strong>\u3002<\/p>\n\n\n\n<p>\u691c\u67fb\u306e\u5185\u5bb9\u30fb\u8cbb\u7528\u30fb\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f <a href=\"\/nipt\/nipt\/autosomal-recessive-inheritance\/\">\u30ad\u30e3\u30ea\u30a2\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c6\u30b9\u30c8228<\/a> \u306e\u30da\u30fc\u30b8\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u5c02\u9580\u7684\u306a\u89e3\u8aac<\/h2>\n\n\n\n<p>VLDLR\u95a2\u9023\u5c0f\u8133\u4f4e\u5f62\u6210\uff08VLDLR-associated cerebellar hypoplasia, VLDLRCH\uff09\u306f <strong>VLDLR<\/strong>\uff089p24.2\uff09\u306e\u4e21\u30a2\u30ec\u30eb\u5909\u7570\u306b\u3088\u308b\u3002VLDLR\u306fApoER2\uff08LRP8\uff09\u3068\u3068\u3082\u306b\u30ea\u30fc\u30ea\u30f3\u53d7\u5bb9\u4f53\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3001Dab1\u306e\u30ea\u30f3\u9178\u5316\u3092\u4ecb\u3057\u3066\u795e\u7d4c\u7d30\u80de\u306e\u79fb\u52d5\u3092\u5236\u5fa1\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u753b\u50cf\u6240\u898b\u306f\u7279\u5fb4\u7684\u3067\u3001<strong>\u5c0f\u8133\u4f4e\u5f62\u6210\uff08\u866b\u90e8\u512a\u4f4d\uff09\u3001\u8133\u5e79\u306e\u4f4e\u5f62\u6210\u3001\u5927\u8133\u76ae\u8cea\u306e\u8133\u56de\u5358\u7d14\u5316\uff08simplified gyral pattern\uff09<\/strong>\u306e\u4e09\u5fb4\u3092\u5448\u3059\u308b\u3002\u3053\u306e\u7d44\u307f\u5408\u308f\u305b\u306f\u30ea\u30fc\u30ea\u30f3\u7d4c\u8def\u306e\u969c\u5bb3\u3092\u793a\u5506\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u672c\u75c7\u306f2005\u5e74\u306b<strong>\u30d5\u30c3\u30bf\u30fc\u6d3e\uff08Hutterite\uff09<\/strong>\u306b\u304a\u3051\u308b\u300c\u30c7\u30a3\u30b9\u30a8\u30af\u30a3\u30ea\u30d6\u30ea\u30a6\u30e0\u75c7\u5019\u7fa4\u300d\u306e\u539f\u56e0\u3068\u3057\u3066\u540c\u5b9a\u3055\u308c\u305f\u3002\u56db\u8db3\u6b69\u884c\uff08quadrupedal gait\uff09\u3092\u793a\u3059\u5bb6\u7cfb\u304c\u5831\u544a\u3055\u308c\u3001\u305d\u306e\u9032\u5316\u5b66\u7684\u89e3\u91c8\u3092\u3081\u3050\u3063\u3066\u8b70\u8ad6\u3092\u547c\u3093\u3060\u304c\u3001\u73fe\u5728\u3067\u306f<strong>\u91cd\u5ea6\u306e\u5931\u8abf\u306b\u5bfe\u3059\u308b\u4ee3\u511f\u7684\u306a\u79fb\u52d5\u69d8\u5f0f<\/strong>\u3068\u7406\u89e3\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n\n<p><strong>RELN<\/strong> \u5909\u7570\u3067\u306f\u3001\u3088\u308a\u91cd\u7be4\u306a\u6ed1\u8133\u75c7\u3092\u4f34\u3046\u5c0f\u8133\u4f4e\u5f62\u6210\uff08LCH\uff09\u3092\u5448\u3059\u308b\u3002\u4e21\u8005\u306f\u30ea\u30fc\u30ea\u30f3\u7d4c\u8def\u306e\u7570\u306a\u308b\u968e\u5c64\u306e\u969c\u5bb3\u3067\u3042\u308a\u3001\u753b\u50cf\u3068\u907a\u4f1d\u5b66\u7684\u691c\u67fb\u306b\u3088\u308b\u9451\u5225\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Q. \u56db\u8db3\u6b69\u884c\u306b\u306a\u308b\u3068\u805e\u304d\u307e\u3057\u305f\u3002<\/h3>\n\n\n\n<p>A. \u4e00\u90e8\u306e\u65b9\u306b\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u6b69\u304d\u65b9\u3067\u3001\u30d0\u30e9\u30f3\u30b9\u304c\u53d6\u308a\u306b\u304f\u3044\u3053\u3068\u306b\u5bfe\u3059\u308b\u4f53\u306e\u5de5\u592b\u3068\u7406\u89e3\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u65b9\u306b\u8d77\u3053\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Q. \u6b69\u3051\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u304b\uff1f<\/h3>\n\n\n\n<p>A. \u500b\u4eba\u5dee\u304c\u5927\u304d\u304f\u3001\u88dc\u52a9\u5177\u3092\u4f7f\u3063\u3066\u6b69\u3051\u308b\u65b9\u304b\u3089\u3001\u6b69\u884c\u306e\u7372\u5f97\u304c\u96e3\u3057\u3044\u65b9\u307e\u3067\u3055\u307e\u3056\u307e\u3067\u3059\u3002\u7406\u5b66\u7642\u6cd5\u3092\u65e9\u304f\u304b\u3089\u7d9a\u3051\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Q. \u77e5\u7684\u306a\u767a\u9054\u306f\u3069\u3046\u3067\u3059\u304b\uff1f<\/h3>\n\n\n\n<p>A. \u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u3092\u4f34\u3046\u3053\u3068\u304c\u591a\u3044\u3068\u3055\u308c\u307e\u3059\u3002\u7642\u80b2\u3068\u6559\u80b2\u306e\u652f\u63f4\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Q. \u9032\u884c\u3057\u307e\u3059\u304b\uff1f<\/h3>\n\n\n\n<p>A. \u751f\u307e\u308c\u3064\u304d\u306e\u8133\u306e\u5f62\u306e\u554f\u984c\u3067\u3042\u308a\u3001\u9032\u884c\u6027\u306b\u60aa\u5316\u3059\u308b\u75c5\u6c17\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u652f\u63f4\u306b\u3088\u3063\u3066\u3067\u304d\u308b\u3053\u3068\u3092\u5897\u3084\u3057\u3066\u3044\u3051\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Q. \u6b21\u306e\u5b50\u3082\u540c\u3058\u75c5\u6c17\u306b\u306a\u308a\u307e\u3059\u304b\uff1f<\/h3>\n\n\n\n<p>A. \u5e38\u67d3\u8272\u4f53\u6f5c\u6027\uff08\u52a3\u6027\uff09\u907a\u4f1d\u3067\u3059\u3002\u3054\u4e21\u89aa\u304c\u3069\u3061\u3089\u3082\u30ad\u30e3\u30ea\u30a2\uff08\u4fdd\u56e0\u8005\uff09\u306e\u5834\u5408\u3001\u598a\u5a20\u306e\u305f\u3073\u306b4\u5206\u306e1\u306e\u78ba\u7387\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Boycott KM, Flavelle S, Bureau A, et al. Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification. <em>Am J Hum Genet<\/em>. 2005;77(3):477-483.<\/li>\n\n\n\n<li>Ozcelik T, Akarsu N, Uz E, et al. Mutations in the very low-density lipoprotein receptor VLDLR cause cerebellar hypoplasia and quadrupedal locomotion in humans. <em>Proc Natl Acad Sci U S A<\/em>. 2008;105(11):4232-4236.<\/li>\n\n\n\n<li>Boycott KM, Bonnemann C, Herz J, et al. Mutations in VLDLR as a cause for autosomal recessive cerebellar ataxia with mental retardation (dysequilibrium syndrome). <em>J Child Neurol<\/em>. 2009;24(10):1310-1315.<\/li>\n\n\n\n<li>OMIM #224050 Cerebellar hypoplasia and mental retardation with or without quadrupedal locomotion 1<\/li>\n\n\n<\/ul>\n","protected":false},"featured_media":0,"menu_order":0,"template":"page_gd.php","class_list":["post-136699","genetic-diseases","type-genetic-diseases","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/136699","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/genetic-diseases"}],"version-history":[{"count":1,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/136699\/revisions"}],"predecessor-version":[{"id":137069,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/136699\/revisions\/137069"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=136699"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}