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class=\"wp-block-list\">\n<li><strong>\u30d6\u30c9\u30a6\u7cd6\u306e\u70b9\u6ef4\u3068\u983b\u56de\u306e\u6388\u4e73\u30fb\u6804\u990a<\/strong>\uff1a\u8840\u7cd6\u3092\u4fdd\u3064\u305f\u3081\u306e\u57fa\u672c\u3067\u3059\u3002\u80c3\u306b\u7ba1\u3092\u5165\u308c\u3066\u6301\u7d9a\u7684\u306b\u6804\u990a\u3092\u5165\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059<\/li>\n\n\n\n<li><strong>\u30b8\u30a2\u30be\u30ad\u30b7\u30c9\uff08\u306e\u307f\u85ac\uff09<\/strong>\uff1a\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u5206\u6ccc\u3092\u304a\u3055\u3048\u308b\u85ac\u3067\u3059\u304c\u3001KATP\u30c1\u30e3\u30cd\u30eb\u305d\u306e\u3082\u306e\u304c\u6b20\u3051\u3066\u3044\u308b\u5834\u5408\u306f\u52b9\u304d\u306b\u304f\u3044\u3053\u3068\u304c\u3042\u308a\u307e\u3059<\/li>\n\n\n\n<li><strong>\u30aa\u30af\u30c8\u30ec\u30aa\u30c1\u30c9\u306a\u3069\u306e\u6ce8\u5c04\u85ac\u3001\u30b0\u30eb\u30ab\u30b4\u30f3<\/strong>\uff1a\u30b8\u30a2\u30be\u30ad\u30b7\u30c9\u304c\u52b9\u304b\u306a\u3044\u5834\u5408\u306b\u4f7f\u308f\u308c\u307e\u3059<\/li>\n\n\n\n<li><strong>\u624b\u8853<\/strong>\uff1a\u5c40\u6240\u578b\u3067\u306f\u75c5\u5909\u90e8\u5206\u3092\u5207\u308a\u53d6\u308b\u3053\u3068\u3067\u6539\u5584\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002\u85ac\u3067\u8840\u7cd6\u304c\u4fdd\u3066\u306a\u3044\u3073\u307e\u3093\u578b\u3067\u306f\u3001\u3059\u3044\u81d3\u306e\u5927\u90e8\u5206\u3092\u5207\u9664\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u5c06\u6765\u306e\u7cd6\u5c3f\u75c5\u306a\u3069\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059<\/li>\n\n\n\n<li><strong>\u767a\u9054\u306e\u898b\u5b88\u308a\u3068\u7642\u80b2<\/strong>\uff1a\u4f4e\u8840\u7cd6\u306e\u5f71\u97ff\u304c\u306a\u3044\u304b\u3001\u6210\u9577\u306b\u5408\u308f\u305b\u3066\u78ba\u8a8d\u3057\u307e\u3059<\/li>\n\n\n<\/ul>\n\n\n<p class=\"wp-block-paragraph\">\u5e74\u9f62\u3068\u3068\u3082\u306b\u4f4e\u8840\u7cd6\u304c\u8d77\u304d\u306b\u304f\u304f\u306a\u308a\u3001\u6cbb\u7642\u3092\u6e1b\u3089\u305b\u308b\u304a\u5b50\u3055\u307e\u3082\u3044\u307e\u3059\u3002<strong>\u5c02\u9580\u306e\u533b\u7642\u6a5f\u95a2\u3067\u3001\u9577\u671f\u306b\u308f\u305f\u3063\u3066\u7d4c\u904e\u3092\u307f\u3066\u3044\u304f\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/strong><\/p>\n\n\n<h2 class=\"wp-block-heading\">\u3053\u306e\u75be\u60a3\u306f\u691c\u67fb\u3067\u308f\u304b\u308a\u307e\u3059<\/h2>\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u75be\u60a3\u306f\u3001\u539f\u56e0\u3068\u306a\u308b <strong>KCNJ11<\/strong> \u907a\u4f1d\u5b50\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u767a\u75c7\u524d\u3084\u51fa\u751f\u524d\u306b\u898b\u3064\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30afNIPT\u3067\u306f\u6b21\u306e\u691c\u67fb\u3092\u3054\u7528\u610f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u3092\u7528\u3044\u305f\u691c\u67fb\uff081,200\u7a2e\u985e\u4ee5\u4e0a\uff09<\/h3>\n\n\n<p class=\"wp-block-paragraph\">\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u306f\u3001\u907a\u4f1d\u5b50\u306e\u3046\u3061\u305f\u3093\u3071\u304f\u8cea\u306e\u8a2d\u8a08\u56f3\u306b\u3042\u305f\u308b\u90e8\u5206\uff08\u30a8\u30af\u30bd\u30f3\uff09\u3092\u307e\u3068\u3081\u3066\u8aad\u307f\u53d6\u308b\u691c\u67fb\u3067\u3059\u3002\u3053\u306e\u89e3\u6790\u3092\u884c\u3063\u305f\u3046\u3048\u3067\u3001<strong>KCNJ11<\/strong> \u907a\u4f1d\u5b50\u3092\u542b\u3080<strong>1,200\u7a2e\u985e\u4ee5\u4e0a<\/strong>\u306e\u907a\u4f1d\u5b50\u3092\u5bfe\u8c61\u306b\u8abf\u3079\u3001<strong>\u3053\u306e\u75be\u60a3\u306e\u539f\u56e0\u3068\u306a\u308b\u5909\u5316\u3092\u691c\u51fa\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059<\/strong>\u3002\u56fd\u5185\u306e\u691c\u67fb\u6240\u3067\u884c\u3044\u3001\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f5\u9031\u9593\u301c7\u9031\u9593\u3067\u3059\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u75be\u60a3\u306f\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\uff08\u52a3\u6027\uff09\u907a\u4f1d\u306e\u305f\u3081\u3001\u3054\u4e21\u89aa\u304c\u3069\u3061\u3089\u3082\u75c7\u72b6\u306e\u306a\u3044\u300c\u30ad\u30e3\u30ea\u30a2\uff08\u4fdd\u56e0\u8005\uff09\u300d\u3067\u3042\u308b\u3068\u304d\u306b\u3001\u304a\u5b50\u3055\u307e\u3054\u3068\u306b<strong>4\u5206\u306e1\u306e\u78ba\u7387<\/strong>\u3067\u767a\u75c7\u3057\u307e\u3059\u3002\u691c\u67fb\u306e\u5185\u5bb9\u30fb\u8cbb\u7528\u30fb\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f <a href=\"\/nipt\/nipt\/carrier-screening-1200\/\">\u30ad\u30e3\u30ea\u30a2\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c6\u30b9\u30c81,200\uff0b\u306e\u30da\u30fc\u30b8<\/a> \u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h2 class=\"wp-block-heading\">\u5c02\u9580\u7684\u306a\u89e3\u8aac<\/h2>\n\n\n<p class=\"wp-block-paragraph\"><strong>KCNJ11<\/strong> \u306f\u5185\u5411\u304d\u6574\u6d41\u6027\u30ab\u30ea\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb Kir6.2 \u3092\u30b3\u30fc\u30c9\u3057\u3001<strong>SUR1\uff08ABCC8\uff09\u3068\u3068\u3082\u306b4:4\u306e\u30d8\u30c6\u30ed\u516b\u91cf\u4f53\u3068\u3057\u3066\u81b5\u03b2\u7d30\u80de\u306eKATP\u30c1\u30e3\u30cd\u30eb\u3092\u69cb\u6210\u3059\u308b<\/strong>\u3002ATP\/ADP\u6bd4\u306e\u4e0a\u6607\u3067\u30c1\u30e3\u30cd\u30eb\u304c\u9589\u3058\u3001\u819c\u306e\u8131\u5206\u6975\u304b\u3089\u96fb\u4f4d\u4f9d\u5b58\u6027\u30ab\u30eb\u30b7\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb\u304c\u958b\u3044\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u8d77\u3053\u308b\u3002<strong>\u6a5f\u80fd\u55aa\u5931\u578b\u5909\u7570\u3067\u306f\u30c1\u30e3\u30cd\u30eb\u304c\u9589\u3058\u305f\u307e\u307e\u3068\u306a\u308a\u3001\u8840\u7cd6\u5024\u306b\u4f9d\u5b58\u3057\u306a\u3044\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u304c\u6301\u7d9a\u3059\u308b<\/strong>\u3002\u4e21\u30a2\u30ec\u30eb\u6027\u5909\u7570\u306b\u3088\u308b\u3073\u307e\u3093\u578b\u306f\u3001\u30c1\u30e3\u30cd\u30eb\u304c\u4f5c\u7528\u70b9\u3067\u3042\u308b\u30b8\u30a2\u30be\u30ad\u30b7\u30c9\u306b<strong>\u4e0d\u5fdc\u6027\u3067\u3042\u308b\u3053\u3068\u304c\u591a\u3044<\/strong>\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\"><strong>KCNJ11 \u3068 ABCC8 \u306f\u3044\u305a\u308c\u308211p15\u306b\u4f4d\u7f6e\u3057\u3001\u5c40\u6240\u578b\u306e\u6a5f\u5e8f\u304c\u5171\u901a\u3059\u308b<\/strong>\u2014\u2014\u7236\u7531\u6765\u306e\u7247\u30a2\u30ec\u30eb\u5909\u7570\u306b\u52a0\u3048\u3001\u75c5\u5909\u90e8\u3067<strong>\u6bcd\u7531\u6765\u306e11p15\u9818\u57df\u304c\u4f53\u7d30\u80de\u30ec\u30d9\u30eb\u3067\u5931\u308f\u308c\u308b\uff08\u7236\u6027\u7247\u89aa\u6027\u30c0\u30a4\u30bd\u30df\u30fc\uff09<\/strong>\u3053\u3068\u3067\u5c40\u6240\u7684\u306a\u817a\u816b\u69d8\u904e\u5f62\u6210\u304c\u751f\u3058\u308b\u3002\u5c40\u6240\u578b\u306f\u6563\u767a\u7684\u306b\u8d77\u3053\u308a\u3001<strong>\u90e8\u5206\u5207\u9664\u3067\u6cbb\u7652\u304c\u671f\u5f85\u3067\u304d\u308b\u4e00\u65b9\u3001\u6b21\u5b50\u518d\u767a\u7387\u306f\u4f4e\u3044<\/strong>\u3002\u307e\u305f KCNJ11 \u306b\u306f\u3001\u6bd4\u8f03\u7684\u8efd\u75c7\u3067\u30b8\u30a2\u30be\u30ad\u30b7\u30c9\u306b\u53cd\u5fdc\u3057\u3084\u3059\u3044<strong>\u9855\u6027\uff08\u512a\u6027\uff09\u907a\u4f1d\u306e\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7<\/strong>\u3092\u8d77\u3053\u3059\u5909\u7570\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<strong>\u53cd\u5bfe\u306b\u6d3b\u6027\u5316\u578b\u5909\u7570\u306f\u6c38\u7d9a\u6027\u65b0\u751f\u5150\u7cd6\u5c3f\u75c5\u3092\u8d77\u3053\u3057\u3001\u91cd\u75c7\u4f8b\u3067\u306f\u767a\u9054\u9045\u6ede\u3068\u3066\u3093\u304b\u3093\u3092\u4f34\u3046\uff08DEND\u75c7\u5019\u7fa4\uff09<\/strong>\u3002\u3053\u306e\u75c5\u578b\u3067\u306f\u30b9\u30eb\u30db\u30cb\u30eb\u5c3f\u7d20\u85ac\u3078\u306e\u5207\u308a\u66ff\u3048\u304c\u6709\u52b9\u306a\u4f8b\u304c\u591a\u304f\u3001\u540c\u4e00\u907a\u4f1d\u5b50\u3067\u75c5\u614b\u3068\u6cbb\u7642\u304c\u6b63\u53cd\u5bfe\u306b\u306a\u308b\u597d\u4f8b\u3067\u3042\u308b\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\">\u9451\u5225\u3068\u3057\u3066\u306f\u3001\u5bb6\u65cf\u6027\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u6027\u4f4e\u8840\u7cd6\u75c71\u578b\uff08<em>ABCC8<\/em>\uff09\u3001\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u8131\u6c34\u7d20\u9175\u7d20\uff08<em>GLUD1<\/em>\uff09\u7570\u5e38\u306b\u3088\u308b\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u30fb\u9ad8\u30a2\u30f3\u30e2\u30cb\u30a2\u8840\u75c7\u75c7\u5019\u7fa4\u3001<em>GCK<\/em>\u30fb<em>HADH<\/em>\u30fb<em>HNF4A<\/em> \u306a\u3069\u306b\u3088\u308b\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u3001\u30d9\u30c3\u30af\u30a6\u30a3\u30ba\u30fb\u30f4\u30a3\u30fc\u30c7\u30de\u30f3\u75c7\u5019\u7fa4\u3001\u7cd6\u5c3f\u75c5\u6bcd\u4f53\u5150\u306e\u4e00\u904e\u6027\u9ad8\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u75c7\u304c\u6319\u304c\u308b\u3002<strong>\u907a\u4f1d\u5f62\u5f0f\uff08\u6f5c\u6027\u30fb\u9855\u6027\u30fb\u6563\u767a\u6027\uff09\u3001\u3073\u307e\u3093\u578b\u304b\u5c40\u6240\u578b\u304b\u3001\u30b8\u30a2\u30be\u30ad\u30b7\u30c9\u53cd\u5fdc\u6027\u304c\u305d\u308c\u305e\u308c\u7570\u306a\u308b\u305f\u3081\u3001\u907a\u4f1d\u5b50\u8a3a\u65ad\u306f\u6cbb\u7642\u65b9\u91dd\u3068\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u306e\u53cc\u65b9\u306b\u76f4\u7d50\u3059\u308b\u3002<\/strong><\/p>\n\n\n<h2 class=\"wp-block-heading\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n\n\n<h3 class=\"wp-block-heading\">Q. \u6b21\u306e\u304a\u5b50\u3055\u307e\u3078\u306e\u5f71\u97ff\u306f\u3042\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u4e21\u65b9\u306e\u89aa\u304b\u3089\u5909\u5316\u3092\u53d7\u3051\u7d99\u3044\u3067\u767a\u75c7\u3057\u305f\u5834\u5408\u3001\u3054\u4e21\u89aa\u306f\u3069\u3061\u3089\u3082\u30ad\u30e3\u30ea\u30a2\u306e\u305f\u3081\u3001\u304a\u5b50\u3055\u307e\u3054\u3068\u306b4\u5206\u306e1\u306e\u78ba\u7387\u3067\u767a\u75c7\u3057\u307e\u3059\u3002<\/strong>\u4e00\u65b9\u3001\u5c40\u6240\u578b\u306f\u7236\u65b9\u306e\u5909\u5316\u306b\u5076\u7136\u306e\u5909\u5316\u304c\u91cd\u306a\u3063\u3066\u8d77\u3053\u308b\u305f\u3081\u3001\u6b21\u306e\u304a\u5b50\u3055\u307e\u3067\u540c\u3058\u3053\u3068\u304c\u8d77\u3053\u308b\u78ba\u7387\u306f\u4f4e\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<strong>\u898b\u901a\u3057\u304c\u5927\u304d\u304f\u7570\u306a\u308b\u305f\u3081\u3001\u539f\u56e0\u907a\u4f1d\u5b50\u3068\u75c5\u578b\u3092\u78ba\u5b9a\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/strong><\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u598a\u5a20\u4e2d\u306b\u5206\u304b\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u8d85\u97f3\u6ce2\u691c\u67fb\u3067\u8d64\u3061\u3083\u3093\u304c\u5927\u304d\u3081\u3068\u8a00\u308f\u308c\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u3060\u3051\u3067\u3053\u306e\u75c5\u6c17\u3068\u5206\u304b\u308b\u3053\u3068\u306f\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002<\/strong>\u524d\u306e\u304a\u5b50\u3055\u307e\u3067\u539f\u56e0\u306e\u5909\u5316\u304c\u5206\u304b\u3063\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u51fa\u751f\u524d\u306b\u907a\u4f1d\u5b66\u7684\u691c\u67fb\u3092\u691c\u8a0e\u3067\u304d\u307e\u3059\u3002\u3042\u3089\u304b\u3058\u3081\u5206\u304b\u3063\u3066\u3044\u308c\u3070\u3001\u751f\u307e\u308c\u3066\u3059\u3050\u306b\u8840\u7cd6\u3092\u78ba\u8a8d\u3067\u304d\u308b\u65bd\u8a2d\u3067\u306e\u51fa\u7523\u3092\u6e96\u5099\u3067\u304d\u307e\u3059\u3002\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u540c\u3058\u907a\u4f1d\u5b50\u3067\u7cd6\u5c3f\u75c5\u306b\u306a\u308b\u3053\u3068\u3082\u3042\u308b\u3068\u805e\u304d\u307e\u3057\u305f\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. \u306f\u3044\u3002<strong>KCNJ11 \u907a\u4f1d\u5b50\u306f\u3001\u306f\u305f\u3089\u304d\u304c\u5f31\u307e\u308b\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u51fa\u3059\u304e\uff08\u3053\u306e\u75c5\u6c17\uff09\u3001\u306f\u305f\u3089\u304d\u304c\u5f37\u307e\u308a\u3059\u304e\u308b\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u304c\u51fa\u306a\u304f\u306a\u308a\u3001\u65b0\u751f\u5150\u7cd6\u5c3f\u75c5\u306b\u306a\u308a\u307e\u3059\u3002<\/strong>\u540c\u3058\u907a\u4f1d\u5b50\u3067\u3082\u5909\u5316\u306e\u3057\u304b\u305f\u306b\u3088\u3063\u3066\u75c5\u6c17\u3082\u6cbb\u7642\u3082\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u3059\u3044\u81d3\u3092\u5927\u304d\u304f\u5207\u9664\u3059\u308b\u624b\u8853\u3092\u53d7\u3051\u305f\u5834\u5408\u306b\u306f\u3001\u6210\u9577\u3057\u3066\u304b\u3089\u7cd6\u5c3f\u75c5\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u5927\u304d\u304f\u306a\u3063\u3066\u304b\u3089\u3082\u4f4e\u8840\u7cd6\u306f\u7d9a\u304d\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u7d4c\u904e\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u5e74\u9f62\u3068\u3068\u3082\u306b\u4f4e\u8840\u7cd6\u304c\u8d77\u3053\u308a\u306b\u304f\u304f\u306a\u308a\u3001\u6cbb\u7642\u3092\u6e1b\u3089\u305b\u308b\u304a\u5b50\u3055\u307e\u3082\u3044\u307e\u3059\u3002<\/strong>\u305f\u3060\u3057\u3001\u4e73\u5150\u671f\u306e\u4f4e\u8840\u7cd6\u306e\u5f71\u97ff\u304c\u6b8b\u308b\u3053\u3068\u3082\u3042\u308b\u305f\u3081\u3001\u8840\u7cd6\u306e\u7ba1\u7406\u3068\u3042\u308f\u305b\u3066\u767a\u9054\u3092\u9577\u304f\u898b\u5b88\u3063\u3066\u3044\u304f\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u306f\u4f55\u3092\u76f8\u8ac7\u3067\u304d\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. \u8a3a\u65ad\u306e\u610f\u5473\u3001\u6b21\u306e\u304a\u5b50\u3055\u307e\u3078\u306e\u5f71\u97ff\u3001\u51fa\u751f\u524d\u691c\u67fb\u3084\u7740\u5e8a\u524d\u691c\u67fb\u306e\u9078\u629e\u80a2\u3001\u3054\u304d\u3087\u3046\u3060\u3044\u3084\u3054\u89aa\u65cf\u3078\u306e\u5f71\u97ff\u306a\u3069\u3092\u3054\u76f8\u8ac7\u3044\u305f\u3060\u3051\u307e\u3059\u3002\u5224\u65ad\u3092\u6025\u304c\u305b\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n<ul class=\"wp-block-list\">\n<li>OMIM #601820 Hyperinsulinemic hypoglycemia, familial, 2; HHF2. Online Mendelian Inheritance in Man.<\/li>\n\n\n\n<li>Thomas P, Ye Y, Lightner E. Mutation of the pancreatic islet inward rectifier Kir6.2 also leads to familial persistent hyperinsulinemic hypoglycemia of infancy. <em>Hum Mol Genet<\/em>. 1996;5(11):1809-1812.<\/li>\n\n\n\n<li>Gloyn AL, Pearson ER, Antcliff JF, et al. Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes. <em>N Engl J Med<\/em>. 2004;350(18):1838-1849.<\/li>\n\n\n\n<li>Snider KE, Becker S, Boyajian L, et al. Genotype and phenotype correlations in 417 children with congenital hyperinsulinism. <em>J Clin Endocrinol Metab<\/em>. 2013;98(2):E355-E363.<\/li>\n\n\n\n<li>Rosenfeld E, Ganguly A, De Leon DD. Congenital hyperinsulinism disorders: Genetic and clinical characteristics. <em>Am J Med Genet C Semin Med Genet<\/em>. 2019;181(4):682-692.<\/li>\n\n\n<\/ul>\n","protected":false},"featured_media":0,"menu_order":0,"template":"page_gd.php","class_list":["post-147405","genetic-diseases","type-genetic-diseases","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/147405","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/genetic-diseases"}],"version-history":[{"count":0,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/147405\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=147405"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}