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class=\"wp-block-heading\">\u539f\u56e0<\/h2>\n\n\n<p class=\"wp-block-paragraph\"><strong>KCNJ1<\/strong> \u907a\u4f1d\u5b50\u306f\u3001\u814e\u81d3\u306e\u5c3f\u7d30\u7ba1\u3067\u306f\u305f\u3089\u304f<strong>\u30ab\u30ea\u30a6\u30e0\u306e\u901a\u308a\u9053\uff08ROMK \u3068\u547c\u3070\u308c\u308b\u30ab\u30ea\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb\uff09<\/strong>\u306e\u8a2d\u8a08\u56f3\u3067\u3059\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\">\u814e\u81d3\u306e\u300c\u30d8\u30f3\u30ec\u306e\u30eb\u30fc\u30d7\u300d\u3068\u3044\u3046\u90e8\u5206\u3067\u306f\u3001\u5c3f\u304b\u3089\u5869\u5206\u3092\u4f53\u306b\u53d6\u308a\u623b\u3059\u3057\u304f\u307f\u304c\u306f\u305f\u3089\u3044\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u3057\u304f\u307f\u306f\u3001<strong>\u3044\u3063\u305f\u3093\u53d6\u308a\u8fbc\u3093\u3060\u30ab\u30ea\u30a6\u30e0\u3092 ROMK 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href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/premature-birth\/\">\u65e9\u7523<\/a>\u30fb\u4f4e\u51fa\u751f\u4f53\u91cd<\/strong>\uff1a\u7f8a\u6c34\u904e\u591a\u306b\u3068\u3082\u306a\u3063\u3066\u8d77\u3053\u308a\u3084\u3059\u304f\u306a\u308a\u307e\u3059<\/li>\n\n\n\n<li><strong>\u591a\u5c3f\u3068\u8131\u6c34<\/strong>\uff1a\u751f\u307e\u308c\u305f\u3042\u3068\u3082\u5c3f\u304c\u975e\u5e38\u306b\u591a\u304f\u3001\u4f53\u91cd\u304c\u6e1b\u308a\u3084\u3059\u304f\u306a\u308a\u307e\u3059<\/li>\n\n\n\n<li><strong>\u65b0\u751f\u5150\u671f\u306e\u4e00\u6642\u7684\u306a\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7<\/strong>\uff1a<strong>2\u578b\u306b\u7279\u5fb4\u7684\u306a\u6240\u898b\u3067\u3059<\/strong>\u3002\u305d\u306e\u5f8c\u306f\u4f4e\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u3078\u79fb\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059<\/li>\n\n\n\n<li>\u8840\u6db2\u304c\u30a2\u30eb\u30ab\u30ea\u6027\u306b\u50be\u304f\uff08\u4ee3\u8b1d\u6027\u30a2\u30eb\u30ab\u30ed\u30fc\u30b7\u30b9\uff09<\/li>\n\n\n\n<li><strong>\u5c3f\u306b\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u591a\u304f\u51fa\u308b\u3053\u3068\u3068\u3001\u814e\u77f3\u7070\u5316<\/strong>\uff1a\u814e\u81d3\u306b\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u6c88\u7740\u3057\u3001\u9577\u3044\u76ee\u3067\u814e\u81d3\u306e\u306f\u305f\u3089\u304d\u306b\u5f71\u97ff\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059<\/li>\n\n\n\n<li>\u767a\u71b1\u3001\u5614\u5410\u3001\u54fa\u4e73\u4e0d\u826f\u3001\u4f53\u91cd\u304c\u5897\u3048\u306b\u304f\u3044\u3001\u6210\u9577\u306e\u9045\u308c<\/li>\n\n\n<\/ul>\n\n\n<h2 class=\"wp-block-heading\">\u691c\u67fb\u30fb\u8a3a\u65ad<\/h2>\n\n\n<p 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class=\"wp-block-paragraph\"><strong>\u73fe\u6642\u70b9\u3067\u3001\u907a\u4f1d\u5b50\u306e\u5909\u5316\u305d\u306e\u3082\u306e\u3092\u6cbb\u3059\u6cbb\u7642\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong>\u5931\u308f\u308c\u308b\u6c34\u5206\u3068\u5869\u5206\u3092\u88dc\u3044\u3001\u4f53\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u6574\u3048\u308b\u6cbb\u7642\u3092\u7d9a\u3051\u308b\u3053\u3068\u3067\u3001<strong>\u591a\u304f\u306e\u304a\u5b50\u3055\u307e\u304c\u6210\u9577\u3057\u3001\u65e5\u5e38\u751f\u6d3b\u3092\u9001\u308c\u308b\u3088\u3046\u306b\u306a\u308b\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u307e\u3059<\/strong>\u3002<\/p>\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6c34\u5206\u3068\u5869\u5206\u306e\u88dc\u7d66<\/strong>\uff1a\u65b0\u751f\u5150\u671f\u306f\u70b9\u6ef4\u304c\u5fc5\u8981\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u5f8c\u306f\u98f2\u307f\u85ac\u3084\u98df\u4e8b\u3067\u88dc\u3044\u307e\u3059<\/li>\n\n\n\n<li><strong>\u30ab\u30ea\u30a6\u30e0\u306e\u88dc\u7d66<\/strong>\uff1a<strong>2\u578b\u3067\u306f\u751f\u307e\u308c\u305f\u76f4\u5f8c\u306b\u30ab\u30ea\u30a6\u30e0\u304c\u9ad8\u3044\u3053\u3068\u304c\u3042\u308b\u305f\u3081\u3001\u8840\u6db2\u691c\u67fb\u3067\u78ba\u8a8d\u3057\u306a\u304c\u3089\u614e\u91cd\u306b\u59cb\u3081\u307e\u3059<\/strong><\/li>\n\n\n\n<li><strong>\u30d7\u30ed\u30b9\u30bf\u30b0\u30e9\u30f3\u30b8\u30f3\u3092\u6291\u3048\u308b\u85ac\uff08\u30a4\u30f3\u30c9\u30e1\u30bf\u30b7\u30f3\u306a\u3069\uff09<\/strong>\uff1a\u5c3f\u306e\u91cf\u3092\u6e1b\u3089\u3059\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002\u80c3\u8178\u3084\u814e\u81d3\u3078\u306e\u526f\u4f5c\u7528\u306b\u6ce8\u610f\u3057\u306a\u304c\u3089\u3001\u91cf\u3092\u8abf\u6574\u3057\u3066\u4f7f\u3044\u307e\u3059<\/li>\n\n\n\n<li><strong>\u6210\u9577\u30fb\u6804\u990a\u306e\u652f\u63f4<\/strong>\uff1a\u4f53\u91cd\u306e\u5897\u3048\u65b9\u3084\u6210\u9577\u3092\u5b9a\u671f\u7684\u306b\u78ba\u8a8d\u3057\u307e\u3059<\/li>\n\n\n\n<li><strong>\u814e\u81d3\u306e\u5b9a\u671f\u7684\u306a\u691c\u67fb<\/strong>\uff1a\u814e\u77f3\u7070\u5316\u3084\u814e\u81d3\u306e\u306f\u305f\u3089\u304d\u306e\u5909\u5316\u3092\u9577\u304f\u898b\u5b88\u308a\u307e\u3059<\/li>\n\n\n<\/ul>\n\n\n<h2 class=\"wp-block-heading\">\u3053\u306e\u75be\u60a3\u306f\u691c\u67fb\u3067\u308f\u304b\u308a\u307e\u3059<\/h2>\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u75be\u60a3\u306f\u3001\u539f\u56e0\u3068\u306a\u308b <strong>KCNJ1<\/strong> \u907a\u4f1d\u5b50\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u767a\u75c7\u524d\u3084\u51fa\u751f\u524d\u306b\u898b\u3064\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30afNIPT\u3067\u306f\u6b21\u306e\u691c\u67fb\u3092\u3054\u7528\u610f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u3092\u7528\u3044\u305f\u691c\u67fb\uff081,200\u7a2e\u985e\u4ee5\u4e0a\uff09<\/h3>\n\n\n<p class=\"wp-block-paragraph\">\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u306f\u3001\u907a\u4f1d\u5b50\u306e\u3046\u3061\u305f\u3093\u3071\u304f\u8cea\u306e\u8a2d\u8a08\u56f3\u306b\u3042\u305f\u308b\u90e8\u5206\uff08\u30a8\u30af\u30bd\u30f3\uff09\u3092\u307e\u3068\u3081\u3066\u8aad\u307f\u53d6\u308b\u691c\u67fb\u3067\u3059\u3002\u3053\u306e\u89e3\u6790\u3092\u884c\u3063\u305f\u3046\u3048\u3067\u3001<strong>KCNJ1<\/strong> \u907a\u4f1d\u5b50\u3092\u542b\u3080<strong>1,200\u7a2e\u985e\u4ee5\u4e0a<\/strong>\u306e\u907a\u4f1d\u5b50\u3092\u5bfe\u8c61\u306b\u8abf\u3079\u3001<strong>\u3053\u306e\u75be\u60a3\u306e\u539f\u56e0\u3068\u306a\u308b\u5909\u5316\u3092\u691c\u51fa\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059<\/strong>\u3002\u56fd\u5185\u306e\u691c\u67fb\u6240\u3067\u884c\u3044\u3001\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f5\u9031\u9593\u301c7\u9031\u9593\u3067\u3059\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\">\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\uff08\u52a3\u6027\uff09\u907a\u4f1d\u306e\u75be\u60a3\u306f\u3001\u3054\u4e21\u89aa\u304c\u3069\u3061\u3089\u3082\u75c7\u72b6\u306e\u306a\u3044\u300c\u30ad\u30e3\u30ea\u30a2\uff08\u4fdd\u56e0\u8005\uff09\u300d\u3067\u3042\u308b\u3068\u304d\u306b\u3001<strong>4\u5206\u306e1\u306e\u78ba\u7387<\/strong>\u3067\u304a\u5b50\u3055\u307e\u304c\u767a\u75c7\u3057\u307e\u3059\u3002\u691c\u67fb\u306e\u5185\u5bb9\u30fb\u8cbb\u7528\u30fb\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f <a href=\"\/nipt\/nipt\/carrier-screening-1200\/\">\u30ad\u30e3\u30ea\u30a2\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c6\u30b9\u30c81,200\uff0b\u306e\u30da\u30fc\u30b8<\/a> \u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h2 class=\"wp-block-heading\">\u5c02\u9580\u7684\u306a\u89e3\u8aac<\/h2>\n\n\n<p class=\"wp-block-paragraph\"><strong>KCNJ1<\/strong> \u306f\u5185\u5411\u304d\u6574\u6d41\u6027\u30ab\u30ea\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb Kir1.1\uff08ROMK\uff09\u3092\u30b3\u30fc\u30c9\u3057\u3001<strong>\u30d8\u30f3\u30ec\u30eb\u30fc\u30d7\u592a\u3044\u4e0a\u884c\u811a\u306e\u7ba1\u8154\u5074\u819c\u3067\u30ab\u30ea\u30a6\u30e0\u3092\u518d\u5faa\u74b0\u3055\u305b\u3001NKCC2\uff08<em>SLC12A1<\/em>\uff09\u306b\u3088\u308b\u30ca\u30c8\u30ea\u30a6\u30e0\u30fb\u30ab\u30ea\u30a6\u30e0\u30fb\u5869\u7d20\u5171\u8f38\u9001\u3092\u7dad\u6301\u3059\u308b<\/strong>\u3002\u540c\u6642\u306b\u7ba1\u8154\u5074\u6b63\u96fb\u4f4d\u3092\u5f62\u6210\u3057\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u30fb\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u306e\u508d\u7d30\u80de\u7d4c\u8def\u3067\u306e\u518d\u5438\u53ce\u3092\u99c6\u52d5\u3059\u308b\u3002\u6a5f\u80fd\u55aa\u5931\u306b\u3088\u308a NKCC2 \u304c\u5b9f\u8cea\u7684\u306b\u505c\u6b62\u3057\u3001<strong>1\u578b\uff08<em>SLC12A1<\/em>\uff09\u3068\u540c\u7b49\u306e\u91cd\u5ea6\u306e\u5869\u985e\u55aa\u5931\u3001\u9ad8\u30ab\u30eb\u30b7\u30a6\u30e0\u5c3f\u75c7\u3001\u814e\u77f3\u7070\u5316\u3001\u30d7\u30ed\u30b9\u30bf\u30b0\u30e9\u30f3\u30b8\u30f3E2 \u7523\u751f\u4ea2\u9032<\/strong>\u3092\u6765\u3059\uff08\u9ad8\u30d7\u30ed\u30b9\u30bf\u30b0\u30e9\u30f3\u30b8\u30f3E\u75c7\u5019\u7fa4\uff09\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\"><strong>2\u578b\u306e\u8868\u73fe\u578b\u4e0a\u306e\u7279\u7570\u70b9\u306f\u3001\u65b0\u751f\u5150\u671f\u306e\u4e00\u904e\u6027\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u3067\u3042\u308b<\/strong>\u3002ROMK \u306f\u76ae\u8cea\u96c6\u5408\u7ba1\u4e3b\u7d30\u80de\u306b\u304a\u3051\u308b\u30ab\u30ea\u30a6\u30e0\u5206\u6ccc\u306e\u4e3b\u8981\u7d4c\u8def\u3067\u3082\u3042\u308b\u305f\u3081\u3001\u51fa\u751f\u76f4\u5f8c\u306f\u30ab\u30ea\u30a6\u30e0\u6392\u6cc4\u304c\u969c\u5bb3\u3055\u308c\u3001\u507d\u6027\u4f4e\u30a2\u30eb\u30c9\u30b9\u30c6\u30ed\u30f3\u75c71\u578b\u3068\u7d1b\u3089\u308f\u3057\u3044\u6240\u898b\u3092\u5448\u3057\u3046\u308b\u3002\u305d\u306e\u5f8c\u3001\u6d41\u91cf\u4f9d\u5b58\u6027\u306e\u5927\u30b3\u30f3\u30c0\u30af\u30bf\u30f3\u30b9\u30ab\u30ea\u30a6\u30e0\u30c1\u30e3\u30cd\u30eb\u306b\u3088\u308b\u4ee3\u511f\u7684\u5206\u6ccc\u304c\u767a\u9054\u3057\u3001<strong>\u591a\u304f\u306f\u8efd\u5ea6\u306e\u4f4e\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u3078\u79fb\u884c\u3059\u308b\u304c\u3001\u4f4e\u4e0b\u306e\u7a0b\u5ea6\u306f\u4ed6\u306e\u578b\u3088\u308a\u8efd\u3044<\/strong>\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\">\u9451\u5225\u3068\u3057\u3066\u306f\u3001\u30d0\u30fc\u30bf\u30fc\u75c7\u5019\u7fa41\u578b\uff08<em>SLC12A1<\/em>\u3001\u80ce\u5150\u671f\u767a\u75c7\u30fb\u9ad8\u30ab\u30eb\u30b7\u30a6\u30e0\u5c3f\u75c7\uff09\u30013\u578b\uff08<em>CLCNKB<\/em>\u3001\u53e4\u5178\u578b\u3067\u767a\u75c7\u304c\u9045\u304f\u8868\u73fe\u578b\u306e\u5e45\u304c\u5e83\u3044\uff09\u30014a\u578b\uff08<em>BSND<\/em>\uff09\u304a\u3088\u30734b\u578b\uff08<em>CLCNKA<\/em>\uff0f<em>CLCNKB<\/em>\u3001\u611f\u97f3\u96e3\u8074\u3092\u4f34\u3046\uff09\u30015\u578b\uff08<em>MAGED2<\/em>\u3001X\u9023\u9396\u6027\u3067\u80ce\u5150\u671f\u306e\u4e00\u904e\u6027\u7d4c\u904e\uff09\u3001\u30ae\u30c3\u30c6\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\uff08<em>SLC12A3<\/em>\u3001\u4f4e\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u8840\u75c7\u30fb\u4f4e\u30ab\u30eb\u30b7\u30a6\u30e0\u5c3f\u75c7\uff09\u304c\u6319\u304c\u308b\u3002<strong>5\u578b\u306f X \u9023\u9396\u6027\u3067\u518d\u767a\u7387\u306e\u8003\u3048\u65b9\u304c\u7570\u306a\u308a\u3001\u307e\u305f\u81ea\u7136\u306b\u8efd\u5feb\u3057\u3046\u308b\u305f\u3081\u3001\u7f8a\u6c34\u904e\u591a\u3067\u80ce\u5150\u671f\u578b\u304c\u7591\u308f\u308c\u305f\u5834\u5408\u306e\u907a\u4f1d\u5b50\u8a3a\u65ad\u306f\u4e88\u5f8c\u4e88\u6e2c\u3068\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u306b\u76f4\u7d50\u3059\u308b\u3002<\/strong><\/p>\n\n\n<h2 class=\"wp-block-heading\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n\n\n<h3 class=\"wp-block-heading\">Q. \u6b21\u306e\u304a\u5b50\u3055\u307e\u3078\u306e\u5f71\u97ff\u306f\u3042\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u3053\u306e\u75c5\u6c17\u306f\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\u907a\u4f1d\u306e\u305f\u3081\u3001\u3054\u4e21\u89aa\u304c\u3069\u3061\u3089\u3082\u30ad\u30e3\u30ea\u30a2\u306e\u5834\u5408\u3001\u304a\u5b50\u3055\u307e\u3054\u3068\u306b4\u5206\u306e1\u306e\u78ba\u7387\u3067\u767a\u75c7\u3057\u307e\u3059\u3002<\/strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt\/testing\/#anchor_sex\">\u6027\u5225<\/a>\u306b\u3088\u308b\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u30d0\u30fc\u30bf\u30fc\u75c7\u5019\u7fa4\u306e\u4e2d\u306b\u306f X \u9023\u9396\u6027\u306e\u578b\uff085\u578b\uff09\u3082\u3042\u308a\u3001\u518d\u767a\u306e\u8003\u3048\u65b9\u304c\u7570\u306a\u308a\u307e\u3059\u3002<strong>\u539f\u56e0\u907a\u4f1d\u5b50\u3092\u78ba\u5b9a\u3057\u3066\u304a\u304f\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/strong><\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u598a\u5a20\u4e2d\u306b\u5206\u304b\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u591a\u304f\u306f\u598a\u5a20\u4e2d\u671f\u4ee5\u964d\u306e\u8d85\u97f3\u6ce2\u691c\u67fb\u3067\u3001\u539f\u56e0\u306e\u306f\u3063\u304d\u308a\u3057\u306a\u3044\u7f8a\u6c34\u904e\u591a\u3068\u3057\u3066\u6c17\u3065\u304b\u308c\u307e\u3059\u3002<\/strong>\u305f\u3060\u3057\u7f8a\u6c34\u904e\u591a\u306b\u306f\u3055\u307e\u3056\u307e\u306a\u539f\u56e0\u304c\u3042\u308a\u3001\u8d85\u97f3\u6ce2\u691c\u67fb\u3060\u3051\u3067\u3053\u306e\u75c5\u6c17\u3068\u6c7a\u3081\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002\u524d\u306e\u304a\u5b50\u3055\u307e\u3067\u8a3a\u65ad\u304c\u3064\u3044\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u598a\u5a20\u65e9\u671f\u304b\u3089\u306e\u691c\u67fb\u3092\u691c\u8a0e\u3067\u304d\u307e\u3059\u3002\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u4ed6\u306e\u578b\u306e\u30d0\u30fc\u30bf\u30fc\u75c7\u5019\u7fa4\u3068\u306f\u3069\u3046\u9055\u3044\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>2\u578b\u306f\u80ce\u5150\u671f\u304b\u3089\u75c7\u72b6\u304c\u51fa\u308b\u91cd\u3044\u578b\u306e\u4e00\u3064\u3067\u3059\u304c\u3001\u751f\u307e\u308c\u305f\u76f4\u5f8c\u306b\u4e00\u6642\u7684\u306b\u30ab\u30ea\u30a6\u30e0\u304c\u9ad8\u304f\u306a\u308b\u3053\u3068\u3001\u305d\u306e\u5f8c\u306e\u30ab\u30ea\u30a6\u30e0\u306e\u4f4e\u4e0b\u304c\u6bd4\u8f03\u7684\u8efd\u3044\u3053\u3068\u304c\u7279\u5fb4\u3067\u3059\u3002<\/strong>\u96e3\u8074\u3092\u4f34\u3046\u578b\uff084\u578b\uff09\u3068\u306f\u7570\u306a\u308a\u30012\u578b\u3067\u306f\u901a\u5e38\u3001\u805e\u3053\u3048\u306e\u554f\u984c\u306f\u307f\u3089\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u5927\u4eba\u306b\u306a\u308b\u307e\u3067\u6210\u9577\u3067\u304d\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u65b0\u751f\u5150\u671f\u3092\u4e57\u308a\u8d8a\u3048\u3001\u6c34\u5206\u30fb\u5869\u5206\u306e\u88dc\u7d66\u3084\u304a\u85ac\u306b\u3088\u308b\u6cbb\u7642\u3092\u7d9a\u3051\u308b\u3053\u3068\u3067\u3001\u591a\u304f\u306e\u304a\u5b50\u3055\u307e\u304c\u6210\u9577\u3057\u3066\u3044\u304f\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/strong>\u4e00\u65b9\u3067\u3001\u814e\u77f3\u7070\u5316\u306a\u3069\u306b\u3088\u308a\u5e74\u9f62\u3068\u3068\u3082\u306b\u814e\u81d3\u306e\u306f\u305f\u3089\u304d\u304c\u4f4e\u4e0b\u3059\u308b\u65b9\u3082\u3044\u308b\u305f\u3081\u3001\u751f\u6daf\u306b\u308f\u305f\u308b\u5b9a\u671f\u7684\u306a\u901a\u9662\u304c\u5927\u5207\u3067\u3059\u3002\u7d4c\u904e\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u307e\u3059\u306e\u3067\u3001\u4e3b\u6cbb\u533b\u3068\u3088\u304f\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u306f\u4f55\u3092\u76f8\u8ac7\u3067\u304d\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. \u8a3a\u65ad\u306e\u610f\u5473\u3001\u6b21\u306e\u304a\u5b50\u3055\u307e\u3078\u306e\u5f71\u97ff\u3001\u51fa\u751f\u524d\u691c\u67fb\u3084\u7740\u5e8a\u524d\u691c\u67fb\u306e\u9078\u629e\u80a2\u3001\u3054\u304d\u3087\u3046\u3060\u3044\u3084\u3054\u89aa\u65cf\u3078\u306e\u5f71\u97ff\u306a\u3069\u3092\u3054\u76f8\u8ac7\u3044\u305f\u3060\u3051\u307e\u3059\u3002\u5224\u65ad\u3092\u6025\u304c\u305b\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n<ul class=\"wp-block-list\">\n<li>Simon DB, Karet FE, Rodriguez-Soriano J, et al. Genetic heterogeneity of Bartter&#8217;s syndrome revealed by mutations in the K+ channel, ROMK. <em>Nat Genet<\/em>. 1996;14(2):152-156.<\/li>\n\n\n\n<li>Konrad M, Nijenhuis T, Ariceta G, et al. Diagnosis and management of Bartter syndrome: executive summary of the consensus and recommendations from the European Rare Kidney Disease Reference Network Working Group for Tubular Disorders. <em>Kidney Int<\/em>. 2021;99(2):324-335.<\/li>\n\n\n\n<li>Seyberth HW, Schlingmann KP. Bartter- and Gitelman-like syndromes: salt-losing tubulopathies with loop or DCT defects. <em>Pediatr Nephrol<\/em>. 2011;26(10):1789-1802.<\/li>\n\n\n\n<li>Laghmani K, Beck BB, Yang SS, et al. Polyhydramnios, transient antenatal Bartter&#8217;s syndrome, and MAGED2 mutations. <em>N Engl J Med<\/em>. 2016;374(19):1853-1863.<\/li>\n\n\n\n<li>OMIM #241200 Bartter syndrome, type 2, antenatal. Online Mendelian Inheritance in Man.<\/li>\n\n\n<\/ul>\n","protected":false},"featured_media":0,"menu_order":0,"template":"page_gd.php","class_list":["post-147678","genetic-diseases","type-genetic-diseases","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/147678","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/genetic-diseases"}],"version-history":[{"count":0,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/147678\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=147678"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}