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class=\"wp-block-paragraph\">\u78ba\u5b9a\u8a3a\u65ad\u306f<strong>\u907a\u4f1d\u5b66\u7684\u691c\u67fb<\/strong>\u3067\u884c\u3044\u3001\u30b3\u30b1\u30a4\u30f3\u75c7\u5019\u7fa4B\u578b\u3067\u306f <strong>ERCC6<\/strong> \u907a\u4f1d\u5b50\u306b\u7236\u65b9\u30fb\u6bcd\u65b9\u305d\u308c\u305e\u308c\u7531\u6765\u306e\u5909\u5316\u304c\u898b\u3064\u304b\u308a\u307e\u3059\u3002A\u578b\uff08<strong>ERCC8<\/strong>\uff09\u3068\u75c7\u72b6\u3060\u3051\u3067\u898b\u5206\u3051\u308b\u3053\u3068\u306f\u96e3\u3057\u3044\u305f\u3081\u3001<strong>\u3069\u3061\u3089\u306e\u907a\u4f1d\u5b50\u304c\u539f\u56e0\u304b\u3092\u78ba\u5b9a\u3059\u308b\u3053\u3068\u304c\u3001\u3054\u5bb6\u65cf\u306e\u4eca\u5f8c\u306e\u691c\u67fb\u3084\u76f8\u8ac7\u306b\u76f4\u7d50\u3057\u307e\u3059\u3002<\/strong><\/p>\n\n\n<h2 class=\"wp-block-heading\">\u6cbb\u7642<\/h2>\n\n\n<p class=\"wp-block-paragraph\"><strong>\u73fe\u6642\u70b9\u3067\u3001\u3053\u306e\u75c5\u6c17\u3092\u6839\u672c\u304b\u3089\u6cbb\u3059\u6cbb\u7642\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong>\u6cbb\u7642\u306f\u3001\u305d\u308c\u305e\u308c\u306e\u75c7\u72b6\u306b\u5408\u308f\u305b\u305f\u5bfe\u75c7\u7642\u6cd5\u3068\u3001\u751f\u6d3b\u306e\u8cea\u3092\u4fdd\u3064\u305f\u3081\u306e\u652f\u63f4\u304c\u4e2d\u5fc3\u3067\u3059\u3002<strong>\u5c0f\u5150\u79d1\u30fb\u795e\u7d4c\u79d1\u30fb\u773c\u79d1\u30fb\u8033\u9f3b\u79d1\u30fb\u6b6f\u79d1\u30fb\u30ea\u30cf\u30d3\u30ea\u306a\u3069\u3001\u591a\u304f\u306e\u5c02\u9580\u5bb6\u304c\u30c1\u30fc\u30e0\u3067\u304b\u304b\u308f\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/strong><\/p>\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6804\u990a\u306e\u652f\u63f4<\/strong>\uff1a\u98df\u4e8b\u306e\u5de5\u592b\u3084\u3001\u5fc5\u8981\u306b\u5fdc\u3058\u3066\u80c3\u308d\u3046\u306a\u3069\u306b\u3088\u308b\u6804\u990a\u306e\u88dc\u7d66<\/li>\n\n\n\n<li><strong>\u65e5\u5149\u5bfe\u7b56<\/strong>\uff1a\u65e5\u713c\u3051\u6b62\u3081\u3001\u5e3d\u5b50\u3084\u8863\u670d\u306b\u3088\u308b\u7d2b\u5916\u7dda\u306e\u9632\u5fa1<\/li>\n\n\n\n<li><strong>\u76ee\u3068\u8033\u306e\u30b1\u30a2<\/strong>\uff1a\u767d\u5185\u969c\u306e\u624b\u8853\u3001\u88dc\u8074\u5668\u306e\u4f7f\u7528\u3001\u5b9a\u671f\u7684\u306a\u691c\u67fb<\/li>\n\n\n\n<li><strong>\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3<\/strong>\uff1a\u95a2\u7bc0\u306e\u62d8\u7e2e\u306e\u4e88\u9632\u3001\u904b\u52d5\u6a5f\u80fd\u306e\u7dad\u6301<\/li>\n\n\n\n<li><strong>\u5b9a\u671f\u7684\u306a\u5065\u5eb7\u30c1\u30a7\u30c3\u30af<\/strong>\uff1a\u8840\u5727\u3001\u814e\u81d3\u30fb\u809d\u81d3\u306e\u306f\u305f\u3089\u304d\u3001\u6b6f\u306e\u691c\u8a3a<\/li>\n\n\n\n<li><strong>\u304a\u85ac\u3078\u306e\u6ce8\u610f<\/strong>\uff1a\u4e00\u90e8\u306e\u6297\u83cc\u85ac\uff08\u30e1\u30c8\u30ed\u30cb\u30c0\u30be\u30fc\u30eb\uff09\u3067\u91cd\u3044\u809d\u969c\u5bb3\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u670d\u85ac\u306e\u969b\u306f\u4e3b\u6cbb\u533b\u306b\u75c5\u540d\u3092\u5fc5\u305a\u304a\u4f1d\u3048\u304f\u3060\u3055\u3044<\/li>\n\n\n\n<li><strong>\u3054\u5bb6\u65cf\u3078\u306e\u652f\u63f4<\/strong>\uff1a\u7642\u80b2\u30fb\u798f\u7949\u30b5\u30fc\u30d3\u30b9\u306e\u5229\u7528\u3001\u5fc3\u7406\u7684\u306a\u652f\u3048<\/li>\n\n\n<\/ul>\n\n\n<h2 class=\"wp-block-heading\">\u3053\u306e\u75be\u60a3\u306f\u691c\u67fb\u3067\u308f\u304b\u308a\u307e\u3059<\/h2>\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u75be\u60a3\u306f\u3001\u539f\u56e0\u3068\u306a\u308b <strong>ERCC6<\/strong> \u907a\u4f1d\u5b50\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u767a\u75c7\u524d\u3084\u51fa\u751f\u524d\u306b\u898b\u3064\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30afNIPT\u3067\u306f\u6b21\u306e\u691c\u67fb\u3092\u3054\u7528\u610f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u3092\u7528\u3044\u305f\u691c\u67fb\uff081,200\u7a2e\u985e\u4ee5\u4e0a\uff09<\/h3>\n\n\n<p class=\"wp-block-paragraph\">\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u306f\u3001\u907a\u4f1d\u5b50\u306e\u3046\u3061\u305f\u3093\u3071\u304f\u8cea\u306e\u8a2d\u8a08\u56f3\u306b\u3042\u305f\u308b\u90e8\u5206\uff08\u30a8\u30af\u30bd\u30f3\uff09\u3092\u307e\u3068\u3081\u3066\u8aad\u307f\u53d6\u308b\u691c\u67fb\u3067\u3059\u3002\u3053\u306e\u89e3\u6790\u3092\u884c\u3063\u305f\u3046\u3048\u3067\u3001<strong>ERCC6<\/strong> \u907a\u4f1d\u5b50\u3092\u542b\u3080<strong>1,200\u7a2e\u985e\u4ee5\u4e0a<\/strong>\u306e\u907a\u4f1d\u5b50\u3092\u5bfe\u8c61\u306b\u8abf\u3079\u3001<strong>\u3053\u306e\u75be\u60a3\u306e\u539f\u56e0\u3068\u306a\u308b\u5909\u5316\u3092\u691c\u51fa\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059<\/strong>\u3002\u56fd\u5185\u306e\u691c\u67fb\u6240\u3067\u884c\u3044\u3001\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f5\u9031\u9593\u301c7\u9031\u9593\u3067\u3059\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\">\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\uff08\u52a3\u6027\uff09\u907a\u4f1d\u306e\u75be\u60a3\u306f\u3001\u3054\u4e21\u89aa\u304c\u3069\u3061\u3089\u3082\u75c7\u72b6\u306e\u306a\u3044\u300c\u30ad\u30e3\u30ea\u30a2\uff08\u4fdd\u56e0\u8005\uff09\u300d\u3067\u3042\u308b\u3068\u304d\u306b\u3001<strong>\u304a\u5b50\u3055\u307e\u3054\u3068\u306b4\u5206\u306e1\u306e\u78ba\u7387<\/strong>\u3067\u767a\u75c7\u3057\u307e\u3059\u3002\u691c\u67fb\u306e\u5185\u5bb9\u30fb\u8cbb\u7528\u30fb\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f <a href=\"\/nipt\/nipt\/carrier-screening-1200\/\">\u30ad\u30e3\u30ea\u30a2\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c6\u30b9\u30c81,200\uff0b\u306e\u30da\u30fc\u30b8<\/a> \u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h2 class=\"wp-block-heading\">\u5c02\u9580\u7684\u306a\u89e3\u8aac<\/h2>\n\n\n<p class=\"wp-block-paragraph\"><strong>ERCC6<\/strong> \u304c\u30b3\u30fc\u30c9\u3059\u308bCSB\u306f\u3001SWI\/SNF\u578b\u306eATP\u4f9d\u5b58\u6027\u30af\u30ed\u30de\u30c1\u30f3\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u56e0\u5b50\u306b\u5c5e\u3059\u308b\u305f\u3093\u3071\u304f\u8cea\u3067\u3001<strong>\u8ee2\u5199\u5171\u5f79\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u9664\u53bb\u4fee\u5fa9\uff08TC-NER\uff09\u306e\u958b\u59cb\u6bb5\u968e\u3092\u62c5\u3046<\/strong>\u3002\u8ee2\u5199\u4e2d\u306eRNA\u30dd\u30ea\u30e1\u30e9\u30fc\u30bcII\u304cDNA\u640d\u50b7\u3067\u505c\u6b62\u3059\u308b\u3068\u3001CSB\u304c\u3053\u308c\u3092\u8a8d\u8b58\u3057\u3066CSA\uff08<em>ERCC8<\/em>\uff09\u3092\u542b\u3080\u30e6\u30d3\u30ad\u30c1\u30f3\u30ea\u30ac\u30fc\u30bc\u8907\u5408\u4f53\u3084\u4e0b\u6d41\u306e\u4fee\u5fa9\u56e0\u5b50\u3092\u547c\u3073\u8fbc\u3080\u3002\u5168\u30b2\u30ce\u30e0\u578b\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u9664\u53bb\u4fee\u5fa9\uff08GG-NER\uff09\u306f\u4fdd\u305f\u308c\u308b\u305f\u3081\u3001<strong>\u8272\u7d20\u6027\u4e7e\u76ae\u75c7\u3068\u7570\u306a\u308a\u76ae\u819a\u304c\u3093\u306e\u5897\u52a0\u306f\u8a8d\u3081\u306a\u3044<\/strong>\u3002\u795e\u7d4c\u5909\u6027\u3084\u65e9\u8001\u69d8\u75c7\u72b6\u306f\u3001\u4fee\u5fa9\u6b20\u640d\u306b\u52a0\u3048\u3066\u3001<strong>\u9178\u5316\u7684DNA\u640d\u50b7\u3078\u306e\u5bfe\u5fdc\u3001\u8ee2\u5199\u56de\u5fa9\u3001\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a5f\u80fd\u306e\u969c\u5bb3<\/strong>\u304c\u95a2\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\"><strong>\u672c\u907a\u4f1d\u5b50\u306e\u5909\u5316\u306f\u3001\u91cd\u75c7\u5ea6\u306e\u9023\u7d9a\u3057\u305f\u75c5\u578b\u3092\u3064\u304f\u308b<\/strong>\u2014\u2014\u91cd\u75c7\u7aef\u304b\u3089\u9806\u306b\u3001<strong>\u2460\u8133\u30fb\u773c\u30fb\u9854\u30fb\u9aa8\u683c\u75c7\u5019\u7fa41\u578b\uff08COFS1\uff1a\u51fa\u751f\u6642\u304b\u3089\u5148\u5929\u6027\u767d\u5185\u969c\u30fb\u5c0f\u773c\u7403\u30fb\u95a2\u7bc0\u62d8\u7e2e\u304c\u3042\u308a\u3001\u4e73\u5150\u671f\u306b\u6b7b\u4ea1\u3059\u308b\u3053\u3068\u304c\u591a\u3044\uff09\u3001\u2461\u30b3\u30b1\u30a4\u30f3\u75c7\u5019\u7fa4II\u578b\uff08\u5148\u5929\u6027\u30fb\u91cd\u75c7\u578b\uff09\u3001\u2462I\u578b\uff08\u53e4\u5178\u578b\uff09\u3001\u2463III\u578b\uff08\u9045\u767a\u30fb\u8efd\u75c7\u578b\uff09\u3001\u2464\u7d2b\u5916\u7dda\u9ad8\u611f\u53d7\u6027\u75c7\u5019\u7fa41\u578b\uff08UVSS1\uff1a\u65e5\u5149\u904e\u654f\u3068\u305d\u3070\u304b\u3059\u69d8\u8272\u7d20\u6591\u306e\u307f\u3067\u3001\u6210\u9577\u969c\u5bb3\u3084\u795e\u7d4c\u75c7\u72b6\u3092\u6b20\u304f\uff09<\/strong>\u3068\u306a\u308b\u3002<strong>UVSS1\u3067\u306fCSB\u305f\u3093\u3071\u304f\u8cea\u304c\u307b\u307c\u5b8c\u5168\u306b\u6b20\u5931\u3059\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u8efd\u75c7\u3067\u3042\u308b\u4f8b\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u5909\u7570\u306e\u7a2e\u985e\u3068\u91cd\u75c7\u5ea6\u306e\u95a2\u4fc2\u306f\u5358\u7d14\u3067\u306f\u306a\u3044\u3002<\/strong><\/p>\n\n\n<p class=\"wp-block-paragraph\">\u9451\u5225\u3068\u3057\u3066\u306f\u3001\u30b3\u30b1\u30a4\u30f3\u75c7\u5019\u7fa4A\u578b\uff08<em>ERCC8<\/em>\u30015\u756a\u67d3\u8272\u4f53\uff09\u3001\u8272\u7d20\u6027\u4e7e\u76ae\u75c7\u3068\u30b3\u30b1\u30a4\u30f3\u75c7\u5019\u7fa4\u306e\u5408\u4f75\u578b\uff08<em>ERCC2<\/em>\u30fb<em>ERCC3<\/em>\u30fb<em>ERCC5<\/em> \u306a\u3069\u3001\u76ae\u819a\u304c\u3093\u306e\u5371\u967a\u304c\u9ad8\u3044\uff09\u3001\u786b\u9ec4\u6b20\u4e4f\u6027\u6bdb\u9aea\u767a\u80b2\u7570\u5e38\u75c7\u3001\u305d\u306e\u307b\u304b\u306e\u767d\u8cea\u5909\u6027\u75c7\u3084\u5148\u5929\u611f\u67d3\u75c7\u306b\u3088\u308b\u8133\u5185\u77f3\u7070\u5316\u304c\u6319\u304c\u308b\u3002<strong>A\u578b\u3068B\u578b\u306f\u81e8\u5e8a\u50cf\u304b\u3089\u533a\u5225\u3067\u304d\u306a\u3044\u305f\u3081\u3001\u907a\u4f1d\u5b50\u8a3a\u65ad\u306b\u3088\u3063\u3066\u539f\u56e0\u907a\u4f1d\u5b50\u3092\u78ba\u5b9a\u3057\u3001\u3054\u5bb6\u65cf\u306e\u4fdd\u56e0\u8005\u691c\u67fb\u30fb\u51fa\u751f\u524d\u691c\u67fb\u30fb\u7740\u5e8a\u524d\u691c\u67fb\u306e\u5bfe\u8c61\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3042\u308b\u3002<\/strong><\/p>\n\n\n<h2 class=\"wp-block-heading\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n\n\n<h3 class=\"wp-block-heading\">Q. \u6b21\u306e\u304a\u5b50\u3055\u307e\u3078\u306e\u5f71\u97ff\u306f\u3042\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u3053\u306e\u75c5\u6c17\u306f\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\u907a\u4f1d\u306e\u305f\u3081\u3001\u3054\u4e21\u89aa\u304c\u3069\u3061\u3089\u3082\u30ad\u30e3\u30ea\u30a2\u306e\u5834\u5408\u3001\u304a\u5b50\u3055\u307e\u3054\u3068\u306b4\u5206\u306e1\u306e\u78ba\u7387\u3067\u767a\u75c7\u3057\u307e\u3059\u3002<\/strong>2\u5206\u306e1\u306e\u78ba\u7387\u3067\u75c7\u72b6\u306e\u306a\u3044\u30ad\u30e3\u30ea\u30a2\u306b\u30014\u5206\u306e1\u306e\u78ba\u7387\u3067\u5909\u5316\u3092\u53d7\u3051\u7d99\u304c\u306a\u3044\u304a\u5b50\u3055\u307e\u306b\u306a\u308a\u307e\u3059\u3002<strong>\u3054\u5bb6\u65cf\u306e\u907a\u4f1d\u5b50\u306e\u5909\u5316\u304c\u5206\u304b\u3063\u3066\u3044\u308c\u3070\u3001\u6b21\u306e\u598a\u5a20\u3067\u51fa\u751f\u524d\u691c\u67fb\u3084\u7740\u5e8a\u524d\u691c\u67fb\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/strong><\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u598a\u5a20\u4e2d\u306b\u5206\u304b\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u591a\u304f\u306e\u5834\u5408\u3001\u751f\u307e\u308c\u305f\u3068\u304d\u306b\u306f\u76ee\u7acb\u3063\u305f\u75c7\u72b6\u304c\u306a\u3044\u305f\u3081\u3001\u598a\u5a20\u4e2d\u306e\u8d85\u97f3\u6ce2\u691c\u67fb\u3067\u6c17\u3065\u304b\u308c\u308b\u3053\u3068\u306f\u307e\u308c\u3067\u3059\u3002<\/strong>\u91cd\u3044\u578b\u3067\u306f\u3001\u80ce\u5150\u306e\u767a\u80b2\u306e\u9045\u308c\u306a\u3069\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u524d\u306e\u304a\u5b50\u3055\u307e\u3067\u539f\u56e0\u3068\u306a\u308b\u5909\u5316\u304c\u5206\u304b\u3063\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u907a\u4f1d\u5b66\u7684\u691c\u67fb\u3067\u598a\u5a20\u4e2d\u306b\u8abf\u3079\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. A\u578b\u3068B\u578b\u3067\u306f\u4f55\u304c\u9055\u3044\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u539f\u56e0\u3068\u306a\u308b\u907a\u4f1d\u5b50\u304c\u9055\u3044\u307e\u3059\uff08A\u578b\u306f ERCC8\u3001B\u578b\u306f ERCC6\uff09\u3002<\/strong>\u75c7\u72b6\u306f\u3088\u304f\u4f3c\u3066\u3044\u3066\u898b\u305f\u76ee\u3067\u306f\u533a\u5225\u3067\u304d\u307e\u305b\u3093\u304c\u3001B\u578b\u306e\u307b\u3046\u304c\u60a3\u8005\u3055\u3093\u306e\u6570\u304c\u591a\u304f\u3001<strong>\u540c\u3058\u907a\u4f1d\u5b50\u3067\u3001\u3088\u308a\u91cd\u3044\u578b\u304b\u3089\u65e5\u5149\u904e\u654f\u3060\u3051\u306e\u8efd\u3044\u75c5\u6c17\u307e\u3067\u3001\u5e45\u5e83\u3044\u75c7\u72b6\u304c\u8d77\u3053\u308b<\/strong>\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3054\u5bb6\u65cf\u306e\u691c\u67fb\u3067\u306f\u3001\u3069\u3061\u3089\u306e\u907a\u4f1d\u5b50\u304b\u3092\u78ba\u5b9a\u3059\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u65e5\u5149\u306b\u5f53\u305f\u308b\u3068\u76ae\u819a\u304c\u3093\u306b\u306a\u308a\u3084\u3059\u3044\u306e\u3067\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u65e5\u306b\u5f53\u305f\u308b\u3068\u8d64\u304f\u306a\u308a\u3084\u3059\u3044\u65e5\u5149\u904e\u654f\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u4f3c\u305f\u75c5\u6c17\u306e\u8272\u7d20\u6027\u4e7e\u76ae\u75c7\u3068\u9055\u3044\u3001\u76ae\u819a\u304c\u3093\u304c\u5897\u3048\u308b\u3053\u3068\u306f\u77e5\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/strong>\u305d\u308c\u3067\u3082\u3001\u76ae\u819a\u306e\u8ca0\u62c5\u3092\u6e1b\u3089\u3059\u305f\u3081\u306b\u3001\u65e5\u713c\u3051\u6b62\u3081\u3084\u5e3d\u5b50\u306a\u3069\u306e\u65e5\u5149\u5bfe\u7b56\u3092\u304a\u3059\u3059\u3081\u3057\u307e\u3059\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u306f\u4f55\u3092\u76f8\u8ac7\u3067\u304d\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. \u8a3a\u65ad\u306e\u610f\u5473\u3001\u6b21\u306e\u304a\u5b50\u3055\u307e\u3078\u306e\u5f71\u97ff\u3001\u51fa\u751f\u524d\u691c\u67fb\u3084\u7740\u5e8a\u524d\u691c\u67fb\u306e\u9078\u629e\u80a2\u3001\u3054\u304d\u3087\u3046\u3060\u3044\u3084\u3054\u89aa\u65cf\u3078\u306e\u5f71\u97ff\u306a\u3069\u3092\u3054\u76f8\u8ac7\u3044\u305f\u3060\u3051\u307e\u3059\u3002\u5224\u65ad\u3092\u6025\u304c\u305b\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n<ul class=\"wp-block-list\">\n<li>Laugel V. Cockayne Syndrome. In: Adam MP, et al., editors. GeneReviews\u00ae. Seattle (WA): University of Washington, Seattle; 1993-.<\/li>\n\n\n\n<li>OMIM #133540 Cockayne syndrome B; CSB. Online Mendelian Inheritance in Man.<\/li>\n\n\n\n<li>Troelstra C, van Gool A, de Wit J, Vermeulen W, Bootsma D, Hoeijmakers JH. ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne&#8217;s syndrome and preferential repair of active genes. <em>Cell<\/em>. 1992;71(6):939-953.<\/li>\n\n\n\n<li>Nance MA, Berry SA. Cockayne syndrome: review of 140 cases. <em>Am J Med Genet<\/em>. 1992;42(1):68-84.<\/li>\n\n\n\n<li>Laugel V, Dalloz C, Durand M, et al. Mutation update for the CSB\/ERCC6 and CSA\/ERCC8 genes involved in Cockayne syndrome. <em>Hum Mutat<\/em>. 2010;31(2):113-126.<\/li>\n\n\n<\/ul>\n","protected":false},"featured_media":0,"menu_order":0,"template":"page_gd.php","class_list":["post-147867","genetic-diseases","type-genetic-diseases","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/147867","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/genetic-diseases"}],"version-history":[{"count":0,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/147867\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=147867"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}