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class=\"wp-block-paragraph\">\u78ba\u5b9a\u8a3a\u65ad\u306f<strong>\u907a\u4f1d\u5b66\u7684\u691c\u67fb<\/strong>\u3067\u884c\u3044\u3001\u30e0\u30ea\u30d6\u30ec\u30a4\u5c0f\u4eba\u75c7\u3067\u306f <strong>TRIM37<\/strong> \u907a\u4f1d\u5b50\u306b\u7236\u65b9\u30fb\u6bcd\u65b9\u305d\u308c\u305e\u308c\u7531\u6765\u306e\u5909\u5316\u304c\u898b\u3064\u304b\u308a\u307e\u3059\u3002<strong>\u5fc3\u81d3\u30fb\u5185\u5206\u6ccc\u30fb\u816b\u760d\u306b\u3064\u3044\u3066\u9577\u3044\u76ee\u3067\u898b\u5b88\u308b\u8a08\u753b\u3092\u7acb\u3066\u308b\u3046\u3048\u3067\u3082\u3001\u6b21\u306e\u304a\u5b50\u3055\u307e\u306e\u898b\u901a\u3057\u3092\u304a\u4f1d\u3048\u3059\u308b\u3046\u3048\u3067\u3082\u3001\u539f\u56e0\u907a\u4f1d\u5b50\u3092\u78ba\u5b9a\u3059\u308b\u3053\u3068\u306b\u306f\u5927\u304d\u306a\u610f\u5473\u304c\u3042\u308a\u307e\u3059\u3002<\/strong><\/p>\n\n\n<h2 class=\"wp-block-heading\">\u6cbb\u7642<\/h2>\n\n\n<p class=\"wp-block-paragraph\"><strong>\u73fe\u6642\u70b9\u3067\u3001\u3053\u306e\u75c5\u6c17\u305d\u306e\u3082\u306e\u3092\u6cbb\u3059\u6cbb\u7642\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong>\u6cbb\u7642\u306f\u3001\u305d\u308c\u305e\u308c\u306e\u5408\u4f75\u75c7\u3092\u65e9\u3081\u306b\u898b\u3064\u3051\u3066\u5bfe\u51e6\u3059\u308b\u3053\u3068\uff08\u5bfe\u75c7\u7642\u6cd5\uff09\u304c\u4e2d\u5fc3\u3068\u306a\u308a\u3001<strong>\u5c0f\u5150\u79d1\u30fb\u5faa\u74b0\u5668\u79d1\u30fb\u5185\u5206\u6ccc\u79d1\u306a\u3069\u8907\u6570\u306e\u8a3a\u7642\u79d1\u304c\u9023\u643a\u3057\u3066\u898b\u5b88\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/strong><\/p>\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5fc3\u81d3\u306e\u5b9a\u671f\u7684\u306a\u691c\u67fb<\/strong>\uff1a\u53ce\u7e2e\u6027\u5fc3\u819c\u708e\u304c\u9032\u3093\u3067\u5fc3\u4e0d\u5168\u306e\u75c7\u72b6\u304c\u51fa\u305f\u5834\u5408\u306b\u306f\u3001<strong>\u786c\u304f\u306a\u3063\u305f\u5fc3\u819c\u3092\u53d6\u308a\u9664\u304f\u624b\u8853\uff08\u5fc3\u819c\u5207\u9664\u8853\uff09<\/strong>\u304c\u691c\u8a0e\u3055\u308c\u307e\u3059<\/li>\n\n\n\n<li><strong>\u6210\u9577\u3078\u306e\u5bfe\u5fdc<\/strong>\uff1a\u6210\u9577\u30db\u30eb\u30e2\u30f3\u6cbb\u7642\u304c\u691c\u8a0e\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u52b9\u679c\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u4e3b\u6cbb\u533b\u3068\u76f8\u8ac7\u3057\u3066\u5224\u65ad\u3057\u307e\u3059<\/li>\n\n\n\n<li><strong>\u7cd6\u5c3f\u75c5\u30fb\u9ad8\u8840\u5727\u30fb\u8102\u8cea\u7570\u5e38\u306e\u7ba1\u7406<\/strong>\uff1a\u601d\u6625\u671f\u4ee5\u964d\u306f\u7279\u306b\u3001\u5b9a\u671f\u7684\u306a\u691c\u67fb\u3068\u751f\u6d3b\u7fd2\u6163\u306e\u7ba1\u7406\u304c\u52e7\u3081\u3089\u308c\u307e\u3059<\/li>\n\n\n\n<li><strong>\u816b\u760d\u306e\u65e9\u671f\u767a\u898b<\/strong>\uff1a\u814e\u81d3\u3084\u5375\u5de3\u306a\u3069\u3092\u4e2d\u5fc3\u306b\u3001\u5b9a\u671f\u7684\u306a\u753b\u50cf\u691c\u67fb\u306a\u3069\u3067\u898b\u5b88\u308a\u307e\u3059<\/li>\n\n\n\n<li><strong>\u601d\u6625\u671f\u30fb\u598a\u5a20\u306b\u3064\u3044\u3066\u306e\u76f8\u8ac7<\/strong>\uff1a\u5973\u6027\u3067\u306f\u5375\u5de3\u306e\u306f\u305f\u3089\u304d\u306e\u4f4e\u4e0b\u306b\u5bfe\u3057\u3066\u3001\u30db\u30eb\u30e2\u30f3\u88dc\u5145\u304c\u691c\u8a0e\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059<\/li>\n\n\n\n<li><strong>\u3054\u672c\u4eba\u3068\u3054\u5bb6\u65cf\u3078\u306e\u5fc3\u7406\u7684\u30fb\u793e\u4f1a\u7684\u652f\u63f4<\/strong>\uff1a\u4f4e\u8eab\u9577\u306b\u4f34\u3046\u751f\u6d3b\u4e0a\u306e\u5de5\u592b\u3084\u3001\u5b66\u6821\u751f\u6d3b\u3078\u306e\u652f\u63f4\u3082\u5927\u5207\u3067\u3059<\/li>\n\n\n<\/ul>\n\n\n<h2 class=\"wp-block-heading\">\u3053\u306e\u75be\u60a3\u306f\u691c\u67fb\u3067\u308f\u304b\u308a\u307e\u3059<\/h2>\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u75be\u60a3\u306f\u3001\u539f\u56e0\u3068\u306a\u308b <strong>TRIM37<\/strong> \u907a\u4f1d\u5b50\u3092\u8abf\u3079\u308b\u3053\u3068\u3067\u3001\u767a\u75c7\u524d\u3084\u51fa\u751f\u524d\u306b\u898b\u3064\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30afNIPT\u3067\u306f\u6b21\u306e\u691c\u67fb\u3092\u3054\u7528\u610f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u3092\u7528\u3044\u305f\u691c\u67fb\uff081,200\u7a2e\u985e\u4ee5\u4e0a\uff09<\/h3>\n\n\n<p class=\"wp-block-paragraph\">\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\u306f\u3001\u907a\u4f1d\u5b50\u306e\u3046\u3061\u305f\u3093\u3071\u304f\u8cea\u306e\u8a2d\u8a08\u56f3\u306b\u3042\u305f\u308b\u90e8\u5206\uff08\u30a8\u30af\u30bd\u30f3\uff09\u3092\u307e\u3068\u3081\u3066\u8aad\u307f\u53d6\u308b\u691c\u67fb\u3067\u3059\u3002\u3053\u306e\u89e3\u6790\u3092\u884c\u3063\u305f\u3046\u3048\u3067\u3001<strong>TRIM37<\/strong> \u907a\u4f1d\u5b50\u3092\u542b\u3080<strong>1,200\u7a2e\u985e\u4ee5\u4e0a<\/strong>\u306e\u907a\u4f1d\u5b50\u3092\u5bfe\u8c61\u306b\u8abf\u3079\u3001<strong>\u3053\u306e\u75be\u60a3\u306e\u539f\u56e0\u3068\u306a\u308b\u5909\u5316\u3092\u691c\u51fa\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059<\/strong>\u3002\u56fd\u5185\u306e\u691c\u67fb\u6240\u3067\u884c\u3044\u3001\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f5\u9031\u9593\u301c7\u9031\u9593\u3067\u3059\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u75be\u60a3\u306f\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\uff08\u52a3\u6027\uff09\u907a\u4f1d\u306e\u305f\u3081\u3001\u3054\u4e21\u89aa\u304c\u3069\u3061\u3089\u3082\u75c7\u72b6\u306e\u306a\u3044\u300c\u30ad\u30e3\u30ea\u30a2\uff08\u4fdd\u56e0\u8005\uff09\u300d\u3067\u3042\u308b\u3068\u304d\u306b\u3001<strong>\u304a\u5b50\u3055\u307e\u3054\u3068\u306b4\u5206\u306e1\u306e\u78ba\u7387<\/strong>\u3067\u767a\u75c7\u3057\u307e\u3059\u3002\u691c\u67fb\u306e\u5185\u5bb9\u30fb\u8cbb\u7528\u30fb\u7d50\u679c\u307e\u3067\u306e\u671f\u9593\u306f <a href=\"\/nipt\/nipt\/carrier-screening-1200\/\">\u30ad\u30e3\u30ea\u30a2\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c6\u30b9\u30c81,200\uff0b\u306e\u30da\u30fc\u30b8<\/a> \u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h2 class=\"wp-block-heading\">\u5c02\u9580\u7684\u306a\u89e3\u8aac<\/h2>\n\n\n<p class=\"wp-block-paragraph\"><strong>TRIM37<\/strong> \u306f RING \u30d5\u30a3\u30f3\u30ac\u30fc\u30fbB-box\u30fb\u30b3\u30a4\u30eb\u30c9\u30b3\u30a4\u30eb\uff08RBCC\uff09\u30c9\u30e1\u30a4\u30f3\u3092\u3082\u3064 <strong>TRIM \u30d5\u30a1\u30df\u30ea\u30fc\u306e E3 \u30e6\u30d3\u30ad\u30c1\u30f3\u30ea\u30ac\u30fc\u30bc<\/strong>\u3067\u3001\u30da\u30eb\u30aa\u30ad\u30b7\u30bd\u30fc\u30e0\u306b\u5c40\u5728\u3059\u308b\u3002<strong>\u4e2d\u5fc3\u5c0f\u4f53\u306e\u6570\u306e\u5236\u5fa1<\/strong>\u3084\u3001\u30d2\u30b9\u30c8\u30f3 H2A \u306e\u30e2\u30ce\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u3092\u4ecb\u3057\u305f\u8ee2\u5199\u5236\u5fa1\u3078\u306e\u95a2\u4e0e\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\">\u672c\u75c7\u306f<strong>\u30d5\u30a3\u30f3\u30e9\u30f3\u30c9\u75be\u60a3\u907a\u7523\uff08Finnish disease heritage\uff09<\/strong>\u306e\u4e00\u3064\u3067\u3001\u30d5\u30a3\u30f3\u30e9\u30f3\u30c9\u306e\u60a3\u8005\u306e\u5927\u591a\u6570\u306f<strong>\u5358\u4e00\u306e\u5275\u59cb\u8005\u5909\u7570\uff08Fin-major\uff09\u306e\u30db\u30e2\u63a5\u5408<\/strong>\u3067\u3042\u308b\u3002\u4e3b\u8981\u6240\u898b\u306f<strong>\u51fa\u751f\u524d\u767a\u75c7\u306e\u6bd4\u4f8b\u6027\u4f4e\u8eab\u9577\u3001\u4e09\u89d2\u5f62\u9854\u8c8c\u3001\u7db2\u819c\u306e\u9ec4\u8272\u6591\u70b9\u3001J\u5b57\u578b\u30c8\u30eb\u30b3\u978d\u3001\u811b\u9aa8\u306e\u7dda\u7dad\u6027\u9aa8\u7570\u5f62\u6210\u3001\u53ce\u7e2e\u6027\u5fc3\u819c\u708e<\/strong>\u3067\u3001Karlberg \u3089\u306f\u81e8\u5e8a\u6240\u898b\u306b\u57fa\u3065\u304f\u8a3a\u65ad\u57fa\u6e96\u3092\u63d0\u5531\u3057\u3066\u3044\u308b\u3002<strong>\u53ce\u7e2e\u6027\u5fc3\u819c\u708e\u3068\u5fc3\u7b4b\u7dda\u7dad\u5316\u306b\u3088\u308b\u5fc3\u4e0d\u5168\u304c\u4e3b\u8981\u306a\u6b7b\u56e0<\/strong>\u3067\u3042\u308a\u3001\u6210\u4eba\u671f\u306b\u306f<strong>\u30a4\u30f3\u30b9\u30ea\u30f3\u62b5\u6297\u6027\u30fb2\u578b\u7cd6\u5c3f\u75c5\u30fb\u9ad8\u8840\u5727\u3001\u30a6\u30a3\u30eb\u30e0\u30b9\u816b\u760d\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u826f\u6027\u30fb\u60aa\u6027\u816b\u760d\u306e\u9ad8\u983b\u5ea6\u767a\u751f\u3001\u539f\u767a\u6027\u5375\u5de3\u6a5f\u80fd\u4e0d\u5168<\/strong>\u304c\u554f\u984c\u3068\u306a\u308b\u3002<\/p>\n\n\n<p class=\"wp-block-paragraph\">TRIM37 \u306f\u4e73\u304c\u3093\u306a\u3069\u3067 17q23 \u9818\u57df\u306e\u5897\u5e45\u306b\u4f34\u3044\u9ad8\u767a\u73fe\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u308b\u304c\u3001\u3053\u308c\u306f\u4f53\u7d30\u80de\u3067\u306e\u5909\u5316\u3067\u3042\u308a\u3001<strong>\u751f\u6b96\u7d30\u80de\u7cfb\u5217\u306e\u6a5f\u80fd\u55aa\u5931\u5909\u7570\u306b\u3088\u308b\u907a\u4f1d\u6027\u75be\u60a3\u3068\u3057\u3066\u78ba\u7acb\u3057\u3066\u3044\u308b\u306e\u306f\u30e0\u30ea\u30d6\u30ec\u30a4\u5c0f\u4eba\u75c7\u306e\u307f<\/strong>\u3067\u3042\u308b\u3002\u9451\u5225\u3068\u3057\u3066\u306f\u3001\u30b7\u30eb\u30d0\u30fc\u30fb\u30e9\u30c3\u30bb\u30eb\u75c7\u5019\u7fa4\uff0811p15 \u306e\u30a4\u30f3\u30d7\u30ea\u30f3\u30c6\u30a3\u30f3\u30b0\u7570\u5e38\u306a\u3069\uff09\u30013-M \u75c7\u5019\u7fa4\uff08<em>CUL7<\/em>\u3001<em>OBSL1<\/em>\u3001<em>CCDC8<\/em>\uff09\u3001\u5c0f\u982d\u6027\u9aa8\u7570\u5f62\u6210\u6027\u539f\u767a\u6027\u5c0f\u4eba\u75c7\u306a\u3069\u3001\u51fa\u751f\u524d\u767a\u75c7\u306e\u4f4e\u8eab\u9577\u3092\u304d\u305f\u3059\u75be\u60a3\u304c\u6319\u304c\u308b\u3002<strong>\u5fc3\u819c\u75c5\u5909\u30fb\u7db2\u819c\u6240\u898b\u30fb\u30c8\u30eb\u30b3\u978d\u5f62\u614b\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u672c\u75c7\u3092\u793a\u5506\u3057\u3001\u907a\u4f1d\u5b50\u8a3a\u65ad\u306b\u3088\u308a\u9577\u671f\u7ba1\u7406\u8a08\u753b\u306e\u7b56\u5b9a\u3068\u6b21\u5b50\u518d\u767a\u7387\uff0825%\uff09\u306e\u8aac\u660e\u304c\u53ef\u80fd\u3068\u306a\u308b\u3002<\/strong><\/p>\n\n\n<h2 class=\"wp-block-heading\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n\n\n<h3 class=\"wp-block-heading\">Q. \u6b21\u306e\u304a\u5b50\u3055\u307e\u3078\u306e\u5f71\u97ff\u306f\u3042\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u3053\u306e\u75c5\u6c17\u306f\u5e38\u67d3\u8272\u4f53\u6f5c\u6027\u907a\u4f1d\u306e\u305f\u3081\u3001\u3054\u4e21\u89aa\u304c\u3069\u3061\u3089\u3082\u30ad\u30e3\u30ea\u30a2\u306e\u5834\u5408\u3001\u304a\u5b50\u3055\u307e\u3054\u3068\u306b4\u5206\u306e1\u306e\u78ba\u7387\u3067\u767a\u75c7\u3057\u307e\u3059\u3002<\/strong>\u767a\u75c7\u3057\u306a\u304b\u3063\u305f\u304a\u5b50\u3055\u307e\u3082\u30013\u5206\u306e2\u306e\u78ba\u7387\u3067\u30ad\u30e3\u30ea\u30a2\u3068\u306a\u308a\u307e\u3059\uff08\u30ad\u30e3\u30ea\u30a2\u306e\u304b\u305f\u306b\u75c7\u72b6\u306f\u3042\u308a\u307e\u305b\u3093\uff09\u3002<strong>\u6b63\u78ba\u306a\u898b\u901a\u3057\u306e\u305f\u3081\u306b\u3001\u539f\u56e0\u907a\u4f1d\u5b50\u3092\u78ba\u5b9a\u3057\u3066\u304a\u304f\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/strong><\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u598a\u5a20\u4e2d\u306b\u5206\u304b\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u598a\u5a20\u4e2d\u306e\u8d85\u97f3\u6ce2\u691c\u67fb\u3067\u3001\u8d64\u3061\u3083\u3093\u306e\u6210\u9577\u304c\u3086\u3063\u304f\u308a\u3067\u3042\u308b\u3068\u6307\u6458\u3055\u308c\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u308c\u3060\u3051\u3067\u3053\u306e\u75c5\u6c17\u3068\u8a3a\u65ad\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/strong>\u524d\u306e\u304a\u5b50\u3055\u307e\u3067\u8a3a\u65ad\u304c\u3064\u3044\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306b\u3088\u308b<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">\u51fa\u751f\u524d\u8a3a\u65ad<\/a>\u3092\u691c\u8a0e\u3067\u304d\u307e\u3059\u3002\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u77e5\u7684\u306a\u767a\u9054\u306b\u5f71\u97ff\u306f\u3042\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u591a\u304f\u306e\u304b\u305f\u3067\u3001\u77e5\u7684\u767a\u9054\u306f\u304a\u304a\u3080\u306d\u4fdd\u305f\u308c\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/strong>\u4e00\u65b9\u3067\u3001\u7b4b\u8089\u306e\u5f35\u308a\u306e\u5f31\u3055\u306a\u3069\u304b\u3089\u3001\u904b\u52d5\u306e\u767a\u9054\u304c\u3086\u3063\u304f\u308a\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u304a\u5b50\u3055\u307e\u306e\u767a\u9054\u306b\u5408\u308f\u305b\u305f\u652f\u63f4\u3092\u53d7\u3051\u306a\u304c\u3089\u3001\u5b66\u6821\u751f\u6d3b\u3084\u793e\u4f1a\u751f\u6d3b\u3092\u9001\u3063\u3066\u3044\u308b\u304b\u305f\u3082\u591a\u304f\u3044\u3089\u3063\u3057\u3083\u3044\u307e\u3059\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u5927\u4eba\u306b\u306a\u3063\u3066\u304b\u3089\u6c17\u3092\u3064\u3051\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. <strong>\u5fc3\u81d3\u306e\u72b6\u614b\u306b\u52a0\u3048\u3066\u3001\u7cd6\u5c3f\u75c5\u30fb\u9ad8\u8840\u5727\u306e\u7ba1\u7406\u3084\u3001\u816b\u760d\u3092\u65e9\u304f\u898b\u3064\u3051\u308b\u305f\u3081\u306e\u5b9a\u671f\u7684\u306a\u691c\u67fb\u304c\u5927\u5207\u3067\u3059\u3002<\/strong>\u75c7\u72b6\u304c\u306a\u304f\u3066\u3082\u5b9a\u671f\u7684\u306b\u53d7\u8a3a\u3057\u3001\u6c17\u306b\u306a\u308b\u5909\u5316\u304c\u3042\u308c\u3070\u65e9\u3081\u306b\u4e3b\u6cbb\u533b\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n<h3 class=\"wp-block-heading\">Q. \u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u306f\u4f55\u3092\u76f8\u8ac7\u3067\u304d\u307e\u3059\u304b\u3002<\/h3>\n\n\n<p class=\"wp-block-paragraph\">A. \u8a3a\u65ad\u306e\u610f\u5473\u3001\u6b21\u306e\u304a\u5b50\u3055\u307e\u3078\u306e\u5f71\u97ff\u3001\u51fa\u751f\u524d\u691c\u67fb\u3084\u7740\u5e8a\u524d\u691c\u67fb\u306e\u9078\u629e\u80a2\u3001\u3054\u304d\u3087\u3046\u3060\u3044\u3084\u3054\u89aa\u65cf\u3078\u306e\u5f71\u97ff\u306a\u3069\u3092\u3054\u76f8\u8ac7\u3044\u305f\u3060\u3051\u307e\u3059\u3002\u5224\u65ad\u3092\u6025\u304c\u305b\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n<h2 class=\"wp-block-heading\">\u53c2\u8003\u6587\u732e<\/h2>\n\n\n<ul class=\"wp-block-list\">\n<li>Perheentupa J, Autio S, Leisti S, Raitta C, Tuuteri L. Mulibrey nanism, an autosomal recessive syndrome with pericardial constriction. <em>Lancet<\/em>. 1973;2:351-355.<\/li>\n\n\n\n<li>Avela K, Lipsanen-Nyman M, Id\u00e4nheimo N, et al. Gene encoding a new RING-B-box-Coiled-coil protein is mutated in mulibrey nanism. <em>Nat Genet<\/em>. 2000;25(3):298-301.<\/li>\n\n\n\n<li>Karlberg N, Jalanko H, Perheentupa J, Lipsanen-Nyman M. Mulibrey nanism: clinical features and diagnostic criteria. <em>J Med Genet<\/em>. 2004;41(2):92-98.<\/li>\n\n\n\n<li>OMIM #253250 Mulibrey nanism. Online Mendelian Inheritance in Man.<\/li>\n\n\n<\/ul>\n\n","protected":false},"featured_media":0,"menu_order":0,"template":"page_gd.php","class_list":["post-158703","genetic-diseases","type-genetic-diseases","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/158703","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/genetic-diseases"}],"version-history":[{"count":0,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/genetic-diseases\/158703\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=158703"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}