{"id":32052,"date":"2020-12-22T15:13:24","date_gmt":"2020-12-22T06:13:24","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/about-clinic\/amniocentesis\/"},"modified":"2025-10-14T12:24:52","modified_gmt":"2025-10-14T03:24:52","slug":"amniocentesis","status":"publish","type":"page","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/about-clinic\/amniocentesis\/?lang=en","title":{"rendered":"Amniotic fluid testing is important"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"pink-pointbox\">\n<p>\n<span class=\"pink-pointmoji\"><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> (Non-Invasive Prenatal Testing) is not a definitive diagnosis, so a positive result may sometimes occur,<\/span> which might be a <span class=\"pink-pointmoji\">false positive.<\/span> Therefore, in the case of a positive result, amniocentesis is recommended. \n<span class=\"pink-pointmoji\">Hiro Clinic offers financial assistance for amniocentesis<\/span> to support families in reducing their burden.\n<\/p>\n<\/div>\n\n<style>\n.pink-pointbox {\n    background-color: #fff9fb;\n    border-radius: 6px;\n    border: 3px dashed #fdb0bc;\n    font-size: 100%;\n    padding: 10px;\n    margin-bottom: 1rem;\n}\n  .pink-pointbox p {\n    margin-bottom: 0!important;\n}\n  .pink-pointmoji {\n    color: red;\n}\n<\/style>\n\n\n\n<h2>About amniotic fluid testing<\/h2>\n\n\n\n<div class=\"content-img\"><img decoding=\"async\" src=\"\/nipt\/wp-content\/uploads\/2023\/01\/25543162_m.jpg\" alt=\"\u554f\u8a3a\u3059\u308b\u533b\u8005\u3068\u60a3\u8005\"><\/div>\n\n\n\n<p><\/p>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is not a definitive test.<\/p>\n\n\n\n<p>Even if the baby is diagnosed positive, there is a possibility of &#8216;<strong>false positives<\/strong>&#8216;, where the baby is negative but is diagnosed positive for a variety of reasons.<\/p>\n\n\n\n<p>For those who test positive, an <strong>amniotic fluid test<\/strong> is recommended as a definitive test.<\/p>\n\n\n\n<!-- Reservation button installed under FV-->\n<section id=\"cv-button\">\n <p class=\"cv-text\">World Class Next Generation <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a><\/p>\n <div class=\"cv-btn new-btn\">\n   <p>New users here<\/p>\n   <div class=\"btn-effect\">\n     <a href=\"https:\/\/www.hiro-clinic.or.jp\/app\/en\/registration\/\"><img src=\"\/nipt\/wp-content\/uploads\/2024\/04\/en-ctap-new202412.png\" alt=\"\u65b0\u898f\u767b\u9332\" fetchpriority=\"high\" loading=\"eager\" decoding=\"sync\"><\/a>\n   <\/div>\n <\/div>\n <div class=\"cv-btn my-btn\">\n   <p>Registered users here<\/p>\n   <div class=\"btn-effect\">\n     <a href=\"https:\/\/www.hiro-clinic.or.jp\/app\/en\/login\/\"><img src=\"\/nipt\/wp-content\/uploads\/2024\/04\/en-ctaor-new202412.png\" alt=\"\u30de\u30a4\u30fc\u30da\u30fc\u30b8\" fetchpriority=\"high\" loading=\"eager\" decoding=\"sync\"><\/a>\n   <\/div>\n <\/div>\n <p class=\"cv-text\">24hours reservation available<\/p>\n<\/section>\n\n<style>\n#cv-button{\n background-color: #fef4f8;\n \/*background-color: #fff8cf;*\/\n background-image: repeating-linear-gradient(45deg,transparent,transparent 5px,rgba(255,255,255,.5) 5px,rgba(255,255,255,.5) 10px);\n padding: 30px;\n}\n.btn-effect{\n max-width: 450px;\n width: 100%;\n margin: 0 auto;\n position:relative;\n overflow:hidden;\n}\n.btn-effect::after {\ncontent:\"\";\nheight:100%;\nwidth:30px;\nposition:absolute;\ntop:-180px;\nleft:0;\nbackground-color: #fff;\nopacity:0;\n-webkit-transform: rotate(45deg);\n-webkit-animation: reflection 2s ease-in-out infinite;\n}\n@keyframes reflection {\n0% { -webkit-transform: scale(0) rotate(45deg); opacity: 0; }\n60% { -webkit-transform: scale(0) rotate(45deg); opacity: 0.8; }\n100% { -webkit-transform: scale(50) rotate(45deg); opacity: 0; }\n}\n.cv-btn p{\n text-align: center !important;\n font-weight: 600 !important;\n font-size: 20px !important;\n margin-bottom: 0 !important;\n color: #333 !important;\n}\n.cv-btn img{\n width: 100%;\n height: auto;\n}\n.cv-text{\n text-align: center;\n font-weight: 700;\n font-size: 1.8rem !important;\n margin-bottom: 0 !important;\n color: #d8436d;\n}\n\n@media screen and (max-width:500px){\n .cv-text{\n   font-size: 20px !important;\n }\n .cv-btn p{\n   font-size: 18px !important;\n }\n}\n<\/style>\n\n\n\n<h3 class=\"wp-block-heading\">What is amniotic fluid testing?<\/h3>\n\n\n\n<p>Amniotic fluid testing is a &#8216;test of the chromosomes themselves in the amniotic fluid&#8217;. The amniotic fluid is taken and examined to find out which of the baby&#8217;s chromosomes are abnormal.<\/p>\n\n\n\n<p>The appropriate time for an amniotic fluid test is said to be between the 15th and 18th week of pregnancy, when the amniotic fluid is increasing, and the test is often carried out within this period.<\/p>\n\n\n\n<p>Conventional amniotic fluid tests include specific genetic analysis methods such as chromosome segregation and FISH.<\/p>\n\n\n\n<p>These tests can reveal the presence or absence of chromosomal abnormalities such as 21 trisomies, which can cause Down&#8217;s syndrome, as well as other genetic abnormalities such as structural abnormalities \u203b\uff11.<br>\u203b\uff11 Inversions, translocations, large deletions and duplications<\/p>\n\n\n\n<p>See also the <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/amniotic-fluid-test\/?lang=en\">Hiro Clinic NIPT column<\/a> for an explanation.<\/p>\n\n\n\n<p class=\"add\">In the unlikely event that the Hiro Clinic <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> 228 genetic test detects a high risk in the genetic combination of the parents, an amniotic fluid test using the NGS method is performed to confirm whether the detected risk is actually passed on to the foetus.\n<\/p>\n<style>\n.add{\nborder:1px dotted #e54c84;\npadding:1rem;\n}\n<\/style>\n\n\n\n<div class=\"content-img\"><img decoding=\"async\" src=\"\/nipt\/wp-content\/uploads\/2023\/01\/25109636_m.jpg\" alt=\"\u304a\u306a\u304b\u306e\u5927\u304d\u3044\u598a\u5a66\"><\/div>\n<style>\n.content-img{\ntext-align:center;\n}\n@media screen and (min-width: 768px){\n.content-img img{\nmax-width:700px;}\n}<\/style>\n\n\n\n<h3 class=\"wp-block-heading\">Amniotic fluid testing support is also available<\/h3>\n\n\n\n<p>Hiro Clinic <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> offers support for amniotic fluid testing organised by partner laboratories. Patients with a positive test result can receive a subsidy of up to JPY 200,000 for the cost of an amniotic fluid test.<\/p>\n\n\n\n<p>Criteria for amniotic fluid testing cost assistance have been established, see <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/plan\/option\/?lang=en\">&#8216;Amniotic fluid testing support&#8217;<\/a> for more information.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">A positive score will be given.<\/h3>\n\n\n\n<p>A Positive Score Report is available free of charge, which provides a combination of a &#8216;positive score&#8217; and a &#8216;positive predictive value&#8217; from the results of <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> tests performed at Hiro Clinic <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> to date.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/about-clinic\/positive-score\/?lang=en\">Read more about positive scores<\/a><\/p>\n\n\n\n<p class=\"has-text-align-right\"><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<!--\n<div class=\"RandomBanner\">\n        <a href=\"https:\/\/www.hiro-clinic.or.jp\/app\/registration\/?wp&amp;__hstc=91750533.e14a9553142f70a882600ff4a9b29df8.1659507847639.1661921752990.1661928010884.30&amp;__hssc=91750533.11.1661928010884&amp;__hsfp=2804886646&amp;_ga=2.172772707.1326110127.1661756776-1609008843.1659507847\" target=\"_blank\" rel=\"noopener\">\n          <picture class=\"RandomBanner_img\">\n            <img decoding=\"async\" src=\"\/nipt\/wp-content\/uploads\/2026\/04\/banner_04-1.webp\" alt=\"\u6700\u77ed2\u65e5\u3067\u7d50\u679c\u5831\u544a\u30d0\u30ca\u30fc\">\n          <\/picture>\n        <\/a>\n<\/div>\n\n<style>\n.page-template-page_wide #main_col .post_content .RandomBanner {\n}\n.page-template-page_wide #main_col .post_content .RandomBanner a{\n     display: block;\n}\n.page-template-page_wide #main_col .post_content .RandomBanner a img{\n  width:100%;\n}\n.RandomBanner_img{\n  height: auto;\n  display: block;\n  text-align: center;\n  width: 50%;\n  margin: 0 auto;\n}\n@media (max-width:770px){\n     .page-template-page_wide #main_col .post_content .RandomBanner {\n          margin-left: 1rem;\n          margin-right: 1rem;\n          padding-bottom: 0;\n          margin-bottom: 0;\n          height: 100px;\n     }\n}\n<\/style>\n-->\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"NIPT (Non-Invasive P&#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/about-clinic\/amniocentesis\/?lang=en\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":1,"featured_media":24908,"parent":31686,"menu_order":142,"comment_status":"closed","ping_status":"closed","template":"page_wide.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-32052","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/pages\/32052","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=32052"}],"version-history":[{"count":11,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/pages\/32052\/revisions"}],"predecessor-version":[{"id":118017,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/pages\/32052\/revisions\/118017"}],"up":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/pages\/31686"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/24908"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=32052"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}