{"id":83132,"date":"2024-07-06T12:46:43","date_gmt":"2024-07-06T03:46:43","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/"},"modified":"2026-06-12T12:24:39","modified_gmt":"2026-06-12T03:24:39","slug":"why-premium-plan","status":"publish","type":"page","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/?lang=en","title":{"rendered":"Major genetic disorders and intellectual disability"},"content":{"rendered":"

Important Facts About NIPT You Should Know While Trying to Conceive<\/h2>\n

First, do you have any of these questions?<\/strong><\/h3>\n

“Isn’t NIPT<\/a> just a test for Down syndrome and three other chromosomal abnormalities?”
That understanding alone might not be enough.<\/p>\n

Most facilities only test for “just three” conditions<\/strong><\/h3>\n

The NIPT<\/a> offered at many medical institutions only tests for these three conditions.<\/p>\n

\n\n\n\n\n\n\n
Number<\/td>\nCondition Name<\/td>\n<\/tr>\n
Chromosome 13<\/td>\nPatau Syndrome<\/td>\n<\/tr>\n
Chromosome 18<\/td>\nEdwards Syndrome<\/td>\n<\/tr>\n
Chromosome 21<\/td>\nDown Syndrome<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n

However, there is something we want you to know.
Chromosomal abnormalities on the 13th and 18th chromosomes are severe conditions where, in many cases, the baby passes away within their first year of life.
In other words, among these three, Down syndrome is the only “condition with a long-term impact after birth.”<\/p>\n

There are chromosomal and genetic abnormalities that have a long-term impact after birth<\/strong><\/h2>\n

There are chromosomal and genetic abnormalities that will continue to affect your child’s growth, development, and daily life for a long time after birth.
The three most typical examples are:<\/p>\n

#1 Down Syndrome (Trisomy 21)<\/h2>\n

What kind of condition is it?<\/h3>\n

This is a condition where there are three copies of the 21st chromosome instead of the usual two.
It is considered the most common chromosomal abnormality.<\/p>\n

What is the probability of it occurring?<\/h3>\n

Globally, it occurs in about 1 in 600 to 800 births.
While the risk increases with maternal age…
There is also data indicating that the majority of babies with Down syndrome are actually born to mothers under 35. Regardless of age, this is highly relevant to everyone who is trying to conceive or is in the early stages of pregnancy.<\/p>\n

Main Symptoms & Characteristics<\/h3>\n