{"id":111404,"date":"2024-06-30T10:27:57","date_gmt":"2024-06-30T01:27:57","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/difference-between-ccfdna-tube-and-dna-bct\/"},"modified":"2025-08-21T16:32:08","modified_gmt":"2025-08-21T07:32:08","slug":"difference-between-ccfdna-tube-and-dna-bct","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/difference-between-ccfdna-tube-and-dna-bct\/?lang=en","title":{"rendered":"Differences Between PAXgene Blood ccfDNA Tube and Streck Cell-Free DNA BCT"},"content":{"rendered":"\n<div style=\"border:solid #ffe6e6 0.8rem;background-color: #fff9f9;padding:3% 5%;margin:1rem 0 3rem;\"><h2 style=\"margin-top:1rem;\">\u3053\u306e\u8a18\u4e8b\u306e\u307e\u3068\u3081<\/h2><p>The PAXgene Blood ccfDNA Tube and the Streck Cell-Free DNA BCT are both products used for the preservation and stabilization of cell-free DNA (ccfDNA) in blood, but they differ in the following aspects.<\/p><\/div>\n\n\n\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/difference-between-ccfdna-tube-and-dna-bct\/?lang=en\/#PAXgene_Blood_ccfDNA_Tube\" >PAXgene Blood ccfDNA Tube<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/difference-between-ccfdna-tube-and-dna-bct\/?lang=en\/#Streck_Cell-Free_DNA_BCT\" >Streck Cell-Free DNA BCT<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/difference-between-ccfdna-tube-and-dna-bct\/?lang=en\/#Summary\" >Summary<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"PAXgene_Blood_ccfDNA_Tube\"><\/span><strong>PAXgene Blood ccfDNA Tube<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>Preservation and stabilization mechanism:<\/strong><strong><br><\/strong> After blood collection, the tube contains reagents designed to stabilize circulating cell-free DNA (ccfDNA) over an extended period.<br>By preventing the breakdown of white blood cells, the purity of the ccfDNA can be maintained at a high level.<\/p>\n\n\n\n<p><strong>Applications:<\/strong><strong><br><\/strong> Primarily used for liquid biopsies in cancer research, prenatal testing, and post-transplant monitoring.<\/p>\n\n\n\n<p><strong>Storage duration:<\/strong><strong><br><\/strong> Can be stored for up to <strong>7 days at room temperature<\/strong>, with the option for even longer preservation under refrigerated conditions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Streck_Cell-Free_DNA_BCT\"><\/span>Streck Cell-Free DNA BCT<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>Preservation and stabilization mechanism:<\/strong><strong><br><\/strong> Contains a patented stabilization reagent that helps maintain the integrity of ccfDNA.<br>It also prevents the lysis of white blood cells in whole blood samples, thereby reducing contamination of the sample with genomic DNA and maintaining sample quality.<\/p>\n\n\n\n<p><strong>Applications:<\/strong><strong><br><\/strong> Widely used for cancer diagnostics and monitoring, non-invasive prenatal testing (<strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a><\/strong>), and post-transplant monitoring.<\/p>\n\n\n\n<p><strong>Storage duration:<\/strong><strong><br><\/strong> Allows for preservation of samples for up to <strong>14 days at room temperature<\/strong>.<\/p>\n\n\n\n    <a href=\"\/nipt\/about-paxgene-blood-ccfdna-tube\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">PAXgene Blood ccfDNA Tube\u306b\u3064\u3044\u3066 <\/div>\n          <div class=\"blog-card-excerpt\">PAXgene Blood ccfDNA Tube\u3092\u4f7f\u7528\u3057\u305f\u51fa\u751f\u524d\u89aa\u5b50\u9451\u5b9a\u3067\u306f\u3001\u598a\u5a66\u306e\u8840\u6db2\u304b\u3089\u80ce\u5150\u306eDNA\u3092\u5b89\u5168\u30fb\u975e\u4fb5\u8972\u7684\u306b\u63a1\u53d6\u53ef\u80fd\u3002\u9ad8\u7cbe\u5ea6...<\/div>\n      <\/div>\n    <\/a>\n\n\n\n<p><strong>About PAXgene Blood ccfDNA Tube<\/strong><\/p>\n\n\n\n<p>When the <strong>PAXgene Blood ccfDNA Tube<\/strong> is used for <strong>non-invasive prenatal parentage testing<\/strong>, it allows the safe and non-invasive collection of fetal DNA from maternal blood with high accuracy and reliability.<\/p>\n\n\n\n<p>For those who wish to analyze the baby\u2019s genetic information, appointments or testing requests can be made as needed.<\/p>\n\n\n\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/nipt\/wp-content\/uploads\/2024\/12\/23463934_s-1.jpg\" alt=\"\u63a1\u8840\" class=\"wp-image-86644\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Summary\"><\/span><strong>Summary<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Both products excel at stabilizing and preserving <strong>circulating cell-free DNA (ccfDNA)<\/strong> from blood samples, but there are important differences in storage duration and specific use conditions.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>PAXgene<\/strong> offers excellent purity but a relatively shorter storage period.<br><\/li>\n\n\n\n<li><strong>Streck<\/strong> allows for <strong>longer preservation<\/strong>, making it particularly suitable when processing delays are expected.<br><\/li>\n<\/ul>\n\n\n\n<p>The decision on which tube to use should be based on the <strong>specific requirements of the research or diagnostic application<\/strong>.<\/p>\n\n\n\n    <a href=\"\/nipt\/ancestry-analysis\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">\u81ea\u5206\u306e\u30eb\u30fc\u30c4\u3092\u77e5\u308b\uff08\u7956\u5148\u89e3\u6790\uff09\u306b\u3064\u3044\u3066 <\/div>\n          <div class=\"blog-card-excerpt\">DNA\u9451\u5b9a\u3092\u7528\u3044\u305f\u7956\u5148\u89e3\u6790\u3067\u3001\u81ea\u5206\u306e\u30eb\u30fc\u30c4\u3084\u6c11\u65cf\u80cc\u666f\u3001\u5bb6\u7cfb\u56f3\u3092\u79d1\u5b66\u7684\u306b\u63a2\u308b\u65b9\u6cd5\u3092\u89e3\u8aac\u300223andMe\u306a\u3069\u4eba\u6c17\u30b5\u30fc\u30d3\u30b9\u3082\u7d39\u4ecb\u3002...<\/div>\n      <\/div>\n    <\/a>\n","protected":false},"excerpt":{"rendered":"\u3053\u306e\u8a18\u4e8b\u306e\u307e\u3068\u3081The PAXgene &#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/difference-between-ccfdna-tube-and-dna-bct\/?lang=en\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":59,"featured_media":79935,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[97],"tags":[],"class_list":["post-111404","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/111404","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/59"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=111404"}],"version-history":[{"count":2,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/111404\/revisions"}],"predecessor-version":[{"id":111410,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/111404\/revisions\/111410"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/79935"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=111404"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=111404"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=111404"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}