{"id":111620,"date":"2024-12-01T12:51:29","date_gmt":"2024-12-01T03:51:29","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/"},"modified":"2025-08-22T11:46:15","modified_gmt":"2025-08-22T02:46:15","slug":"nipt-test-you-can-receive-with-confidence","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en","title":{"rendered":"Safe and Reliable NIPT Testing"},"content":{"rendered":"\n<div style=\"border:solid #ffe6e6 0.8rem;background-color: #fff9f9;padding:3% 5%;margin:1rem 0 3rem;\">\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#Article_Summary\" >Article Summary<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#Why_NIPT_Is_Considered_Safe\" >Why NIPT Is Considered Safe<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#1_A_%E2%80%9CNon-Invasive%E2%80%9D_Test_Completed_with_Just_a_Blood_Draw\" >1. A \u201cNon-Invasive\u201d Test Completed with Just a Blood Draw<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#2_Extremely_High_Accuracy\" >2. Extremely High Accuracy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#3_Available_From_Early_Pregnancy\" >3. Available From Early Pregnancy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#4_Comprehensive_Medical_Support_After_Results\" >4. Comprehensive Medical Support After Results<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#5_Comprehensive_Medical_Support_After_Results\" >5. Comprehensive Medical Support After Results<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#What_NIPT_Non-Invasive_Prenatal_Testing_Is\" >What NIPT (Non-Invasive Prenatal Testing) Is<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#Screening_Chromosomal_Abnormalities_Through_Fetal_DNA\" >Screening Chromosomal Abnormalities Through Fetal DNA<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#Early_Testing_Available_at_Hiro_Clinic\" >Early Testing Available at Hiro Clinic<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#NIPT_Is_a_Screening_Test\" >NIPT Is a Screening Test<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#NIPT_Is_Not_Covered_by_Insurance\" >NIPT Is Not Covered by Insurance<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#Key_Features_and_Benefits_of_NIPT\" >Key Features and Benefits of NIPT<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#Who_Should_Consider_NIPT\" >Who Should Consider NIPT<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#Important_Considerations_When_Undergoing_NIPT\" >Important Considerations When Undergoing NIPT<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#Comparison_NIPT_vs_Other_Prenatal_Tests\" >Comparison: NIPT vs. Other Prenatal Tests<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\/#Summary\" >Summary<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2 style=\"margin-top:1rem;\"><span class=\"ez-toc-section\" id=\"Article_Summary\"><\/span>Article Summary<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The moment pregnancy is confirmed, it is natural to be concerned about the baby\u2019s health. The increasingly recognized \u201c<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> (Non-Invasive Prenatal Testing)\u201d allows highly accurate screening for chromosomal abnormalities in the fetus without burdening the mother. This article explains how <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> works, the testing process, important considerations, and the latest evidence-based updates, offering comprehensive information for expectant mothers and obstetric professionals.\n<\/p><\/div>\n\n\n\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Why_NIPT_Is_Considered_Safe\"><\/span><strong>Why NIPT Is Considered Safe<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> (Non-Invasive Prenatal Testing) has become one of the most popular prenatal screening methods in recent years.<br>One major reason is its <strong>high level of safety for both the mother and the baby<\/strong>, combined with its <strong>exceptional accuracy<\/strong>.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_A_%E2%80%9CNon-Invasive%E2%80%9D_Test_Completed_with_Just_a_Blood_Draw\"><\/span>1. <strong>A \u201cNon-Invasive\u201d Test Completed with Just a Blood Draw<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> only requires drawing blood from the mother\u2019s arm, just like a standard health check.<br>There\u2019s no need to insert a needle near the baby or touch the uterus, which means:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Almost no risk of miscarriage<br><\/li>\n\n\n\n<li>Minimal physical strain<br><\/li>\n<\/ul>\n\n\n\n<p>Little to no pain or discomfort<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_Extremely_High_Accuracy\"><\/span>2. <strong>Extremely High Accuracy<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> analyzes cell-free fetal DNA (cfDNA) in the mother\u2019s blood with high precision.<br>For the following three chromosomal abnormalities, studies report a <strong>detection rate exceeding 99%<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Down syndrome (Trisomy 21)<br><\/li>\n\n\n\n<li>Edwards syndrome (Trisomy 18)<br><\/li>\n\n\n\n<li>Patau syndrome (Trisomy 13)<br><\/li>\n<\/ul>\n\n\n\n<p>In addition, the <strong>positive predictive value<\/strong> (the probability that a positive result actually indicates an abnormality) is very high. Compared to traditional maternal serum marker screening, the risk of false positives or false negatives is significantly lower.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_Available_From_Early_Pregnancy\"><\/span>3. <strong>Available From Early Pregnancy<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>While most clinics perform <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> after <strong>10 weeks of pregnancy<\/strong>, <strong>Hiro Clinic<\/strong> offers early testing starting from <strong>6 weeks<\/strong>, once pregnancy is confirmed by ultrasound.<br>Getting early insight into the baby\u2019s health allows more time for preparation and informed decision-making.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"4_Comprehensive_Medical_Support_After_Results\"><\/span>4. <strong>Comprehensive Medical Support After Results<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is a <strong>screening test<\/strong>, not a diagnostic one. If the result is positive, confirmatory testing such as <strong>amniocentesis<\/strong> is recommended.<br>At Hiro Clinic, doctors handle the entire follow-up process, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Explaining test results<br><\/li>\n\n\n\n<li>Reporting the positive predictive value<br><\/li>\n\n\n\n<li>Referring patients to appropriate medical facilities if needed<br><\/li>\n<\/ul>\n\n\n\n<p>This <strong>end-to-end support<\/strong> ensures patients are not left alone after receiving their results.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"5_Comprehensive_Medical_Support_After_Results\"><\/span>5. <strong>Comprehensive Medical Support After Results<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is a <strong>screening test<\/strong>, not a diagnostic one. If the result is positive, confirmatory testing such as <strong>amniocentesis<\/strong> is recommended.<br>At Hiro Clinic, doctors handle the entire follow-up process, including:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Explaining test results<br><\/li>\n\n\n\n<li>Reporting the positive predictive value<br><\/li>\n\n\n\n<li>Referring patients to appropriate medical facilities if needed<br><\/li>\n<\/ul>\n\n\n\n<p>This <strong>end-to-end support<\/strong> ensures patients are not left alone after receiving their results.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_NIPT_Non-Invasive_Prenatal_Testing_Is\"><\/span><strong>What NIPT (Non-Invasive Prenatal Testing) Is<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>, also known as <strong>Non-Invasive Prenatal Genetic Testing<\/strong>, is a safe prenatal screening method performed with a simple blood draw from the mother.<br>The procedure is the same as a standard blood test, meaning there is <strong>no direct impact or risk<\/strong> to the baby.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Screening_Chromosomal_Abnormalities_Through_Fetal_DNA\"><\/span><strong>Screening Chromosomal Abnormalities Through Fetal DNA<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>During pregnancy, fragments of the baby\u2019s DNA circulate in the mother\u2019s bloodstream.<br><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> analyzes these fragments to assess the likelihood of chromosomal abnormalities with high accuracy.<br>The basic test screens for these three major conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Down syndrome (Trisomy 21):<\/strong> Associated with intellectual disability and developmental delays<br><\/li>\n\n\n\n<li><strong>Edwards syndrome (Trisomy 18):<\/strong> Often life-limiting early in infancy<br><\/li>\n\n\n\n<li><strong>Patau syndrome (Trisomy 13):<\/strong> Often life-limiting early in infancy<br><\/li>\n<\/ul>\n\n\n\n<p>Depending on the testing plan, <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> can also detect:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Fetal sex<br><\/li>\n\n\n\n<li><strong>Sex chromosome abnormalities<\/strong> (e.g., Klinefelter syndrome), which are more common than Down syndrome<br><\/li>\n\n\n\n<li><strong>Microdeletion syndromes<\/strong> associated with intellectual disabilities (e.g., 22q11.2 deletion syndrome), which are particularly important after Down syndrome screening<br><\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Early_Testing_Available_at_Hiro_Clinic\"><\/span><strong>Early Testing Available at Hiro Clinic<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>While most facilities begin testing at <strong>10\u201311 weeks<\/strong>, Hiro Clinic can perform <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> from <strong>6 weeks<\/strong> (after pregnancy confirmation via ultrasound).<br>This allows families to learn about the baby\u2019s condition earlier, providing more time for preparation and peace of mind.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"NIPT_Is_a_Screening_Test\"><\/span><strong>NIPT Is a Screening Test<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is a <strong>non-diagnostic<\/strong> screening. Results are reported as either \u201cpositive\u201d or \u201cnegative.\u201d<br>If the result is positive, further confirmatory testing such as <strong>amniocentesis<\/strong> or <strong>chorionic villus sampling (CVS)<\/strong> is required.<\/p>\n\n\n\n<p><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/nipt\/wp-content\/uploads\/2024\/12\/27747167_s.jpg\" alt=\"\u304a\u306a\u304b\u306e\u5927\u304d\u306a\u598a\u5a66\u3055\u3093\u304c\u3001\u304a\u306a\u304b\u306e\u524d\u3067\u30cf\u30fc\u30c8\u3092\u4f5c\u3063\u3066\u3044\u308b\" class=\"wp-image-84563\"\/><\/figure><\/div>\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"NIPT_Is_Not_Covered_by_Insurance\"><\/span><strong>NIPT Is Not Covered by Insurance<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is a <strong>self-paid<\/strong> service in Japan.<br>The cost, eligibility, and details vary by medical facility, so it\u2019s important to confirm these factors in advance.<br><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Key_Features_and_Benefits_of_NIPT\"><\/span><strong>Key Features and Benefits of NIPT<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><strong>Non-invasive and safe<\/strong><strong><br><\/strong> Performed with a simple blood draw, eliminating the risk of miscarriage and minimizing burden on both the mother and baby.<\/p>\n\n\n\n<p><strong>High accuracy<\/strong><strong><br><\/strong> Detection rates for chromosomal abnormalities exceed <strong>99%<\/strong>, making it one of the most precise screening methods available.<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/early-nipt-august-only\/\">Early<\/a> availability<\/strong><strong><br><\/strong> Testing can start from 10 weeks of pregnancy, allowing early insights into the baby\u2019s health.<\/p>\n\n\n\n<p><strong>Reduced psychological stress<\/strong><strong><br><\/strong> Accurate results help alleviate anxiety and allow mothers to spend their pregnancy with greater peace of mind.<\/p>\n\n\n\n    <a href=\"\/nipt\/foetation-screening\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">\u80ce\u5150\u30c9\u30c3\u30af(\u80ce\u5150\u7cbe\u5bc6\u8d85\u97f3\u6ce2\u691c\u67fb)\u3068\u306f\uff1f\u3010\u533b\u5e2b\u76e3\u4fee\u3011 <\/div>\n          <div class=\"blog-card-excerpt\">\u80ce\u5150\u30c9\u30c3\u30af\u3068\u306f\u3001\u8a73\u7d30\u306a\u8d85\u97f3\u6ce2\u691c\u67fb\u3067\u80ce\u5150\u306e\u5148\u5929\u6027\u7570\u5e38\u306a\u3069\u3092\u8abf\u3079\u308b\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u691c\u67fb\u3067\u3059\u3002\u80ce\u5150\u30c9\u30c3\u30af\u3092\u53d7\u3051\u308b\u3079\u304d\u304b\u304a\u60a9\u307f\u306e\u65b9\u306e\u305f\u3081\u306b\u3001\u80ce\u5150\u30c9\u30c3\u30af...<\/div>\n      <\/div>\n    <\/a>\n\n\n\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Who_Should_Consider_NIPT\"><\/span><strong>Who Should Consider NIPT<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is available to all pregnant women, but it is especially recommended for:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Advanced maternal age (35 years and older):<\/strong> The risk of chromosomal abnormalities increases with age.<br><\/li>\n\n\n\n<li><strong>History of chromosomal abnormalities in previous pregnancies:<\/strong> Family history or previous pregnancy history increases the importance of early risk evaluation.<br><\/li>\n<\/ul>\n\n\n\n<p><strong>High-risk results from other screenings:<\/strong> If other tests such as fetal ultrasounds or serum markers suggest elevated risk, <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is a logical next step.<\/p>\n\n\n\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Important_Considerations_When_Undergoing_NIPT\"><\/span><strong>Important Considerations When Undergoing NIPT<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Not a diagnostic test<\/strong><strong><br><\/strong> A positive <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> result requires confirmatory testing, such as amniocentesis or CVS, to establish a definitive diagnosis.<br><\/li>\n\n\n\n<li><strong>Limited scope<\/strong><strong><br><\/strong> <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> primarily screens for Trisomy 21, 18, and 13. It cannot detect all chromosomal or single-gene disorders.<br><\/li>\n\n\n\n<li><strong>Choose an accredited facility<\/strong><strong><br><\/strong> Testing at a certified facility is recommended, as accredited clinics provide pre-test genetic counseling and deliver more reliable results.<br><\/li>\n<\/ul>\n\n\n\n<p><strong>Cost<\/strong><strong><br><\/strong> As a self-paid service, <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> typically costs <strong>150,000\u2013200,000 yen<\/strong> (approximately $1,000\u2013$1,400 USD).<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Comparison_NIPT_vs_Other_Prenatal_Tests\"><\/span><strong>Comparison: NIPT vs. Other Prenatal Tests<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td><strong>Aspect<\/strong><\/td><td><strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a><\/strong><\/td><td><strong>Fetal Ultrasound (Fetal Screening)<\/strong><\/td><td><strong>Amniocentesis<\/strong><\/td><\/tr><tr><td><strong>Timing<\/strong><\/td><td>From 10 weeks onward<\/td><td>11\u201322 weeks (multiple sessions possible)<\/td><td>16\u201320 weeks<\/td><\/tr><tr><td><strong>Method<\/strong><\/td><td>Maternal blood draw<\/td><td>Ultrasound observation<\/td><td>Amniotic fluid extraction<\/td><\/tr><tr><td><strong>Conditions Detected<\/strong><\/td><td>Trisomy 21, 18, 13<\/td><td>Structural abnormalities, growth restriction risks<\/td><td>Comprehensive chromosomal confirmation<\/td><\/tr><tr><td><strong>Safety<\/strong><\/td><td>Non-invasive and safe<\/td><td>Non-invasive and safe<\/td><td>Small miscarriage risk (0.1\u20130.3%)<\/td><\/tr><tr><td><strong>Accuracy<\/strong><\/td><td>Very high<\/td><td>Limited by visual inspection<\/td><td>Extremely reliable for diagnosis<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Summary\"><\/span><strong>Summary<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is an innovative prenatal screening method that allows for <strong>high-accuracy evaluation of fetal health without putting stress on the mother or baby<\/strong>.<br>It is <strong>non-invasive, safe, and reliable<\/strong>, making it a trusted option for many pregnant women.<\/p>\n\n\n\n<p>However, <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is a <strong>screening test, not a diagnostic one<\/strong>. Positive results should always be followed up with confirmatory testing and genetic counseling.<br>For the best experience and most reliable results, it is recommended to undergo testing with an accredited facility and consult with experienced medical professionals.<\/p>\n\n\n\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"Article Summary The &#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-test-you-can-receive-with-confidence\/?lang=en\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":94,"featured_media":84509,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[97],"tags":[],"class_list":["post-111620","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/111620","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/94"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=111620"}],"version-history":[{"count":2,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/111620\/revisions"}],"predecessor-version":[{"id":111661,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/111620\/revisions\/111661"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/84509"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=111620"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=111620"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=111620"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}