{"id":116933,"date":"2025-09-29T16:56:48","date_gmt":"2025-09-29T07:56:48","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/"},"modified":"2025-10-15T14:25:26","modified_gmt":"2025-10-15T05:25:26","slug":"nipt-negative-amniocentesis","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en","title":{"rendered":"Is Amniocentesis Necessary Even with a Negative NIPT Result? \u2014 Criteria for Retesting"},"content":{"rendered":"\n<p>Introduction<\/p>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> (Non-Invasive Prenatal Testing), now widely recognized as an option in prenatal diagnosis, has gained attention as a non-invasive and highly accurate screening for chromosomal abnormalities such as Down syndrome.<br>However, even when <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> results are \u201cnegative (low risk),\u201d some cases may still require further testing such as amniocentesis, depending on pregnancy progress or fetal findings.<\/p>\n\n\n\n<p>This article focuses on <strong>\u201c<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> retesting\u201d<\/strong>, discussing the reliability of negative results, situations requiring further testing, and medical decision-making criteria based on the latest research and guidelines.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#What_Is_NIPT_Overview_and_Accuracy\" >What Is NIPT? Overview and Accuracy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#What_Does_a_Negative_Low_Risk_Result_Mean\" >What Does a Negative (Low Risk) Result Mean?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#When_Retesting_Amniocentesis_May_Be_Recommended\" >When Retesting (Amniocentesis) May Be Recommended<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#Amniocentesis_Benefits_and_Risks\" >Amniocentesis: Benefits and Risks<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#Key_Points_for_Consulting_Physicians\" >Key Points for Consulting Physicians<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#Expert_Perspective_Negative_%E2%89%A0_Absolute_Reassurance\" >Expert Perspective: Negative \u2260 Absolute Reassurance<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#Importance_of_Genetic_Counseling\" >Importance of Genetic Counseling<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#Misconceptions_and_Clarifications\" >Misconceptions and Clarifications<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#International_Guidelines\" >International Guidelines<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#Clinical_Case_Example\" >Clinical Case Example<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#Cost_and_Psychological_Considerations\" >Cost and Psychological Considerations<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#FAQs\" >FAQs<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\/#Conclusion_Negative_NIPT_Does_Not_Eliminate_the_Need_for_Retesting\" >Conclusion: Negative NIPT Does Not Eliminate the Need for Retesting<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Is_NIPT_Overview_and_Accuracy\"><\/span>What Is NIPT? Overview and Accuracy<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> analyzes fragments of cell-free fetal DNA (cfDNA) in maternal blood to assess the risk of chromosomal abnormalities. It mainly screens for:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Trisomy 21 (Down syndrome)<\/li>\n\n\n\n<li>Trisomy 18 (Edwards syndrome)<\/li>\n\n\n\n<li>Trisomy 13 (Patau syndrome)<\/li>\n<\/ul>\n\n\n\n<p>Detection rates are very high \u2014 sensitivity for trisomy 21 is around 99%. However, it is important to note that <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is a <strong>screening test<\/strong>, not a <strong>diagnostic test<\/strong>.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_Does_a_Negative_Low_Risk_Result_Mean\"><\/span>What Does a Negative (Low Risk) Result Mean?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>A \u201cnegative\u201d or \u201clow risk\u201d <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> result indicates a very low probability of the tested abnormalities, but it does <strong>not<\/strong> guarantee the fetus is free of abnormalities.<br>Possible causes of false negatives include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Low fetal cfDNA fraction (&lt;4%)<\/li>\n\n\n\n<li>Chromosomal mosaicism<\/li>\n\n\n\n<li>Placental mosaicism (discordance between placenta and fetus)<\/li>\n\n\n\n<li>Abnormalities outside <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>\u2019s testing scope<\/li>\n<\/ul>\n\n\n\n<p>Indeed, studies report rare cases where chromosomal abnormalities were detected after birth despite a negative <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"When_Retesting_Amniocentesis_May_Be_Recommended\"><\/span>When Retesting (Amniocentesis) May Be Recommended<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Abnormal Ultrasound Findings<\/strong><br>If mid-pregnancy ultrasound shows signs such as edema, congenital heart defects, or skeletal anomalies, amniocentesis may be advised even after a negative <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>.<\/li>\n\n\n\n<li><strong>High-Risk Factors (Age or Family History)<\/strong><br>Women over 35 or with a family history of chromosomal disorders may require additional testing despite negative results.<\/li>\n\n\n\n<li><strong>Low Fetal cfDNA Fraction<\/strong><br>Some reports indicate the fetal DNA fraction; if below threshold (e.g., 3.5%), detection reliability decreases and retesting is recommended.<\/li>\n\n\n\n<li><strong>For Reassurance<\/strong><br>Some families opt for diagnostic confirmation via amniocentesis to reduce anxiety and obtain certainty.<\/li>\n<\/ol>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Amniocentesis_Benefits_and_Risks\"><\/span>Amniocentesis: Benefits and Risks<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>Benefits<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Nearly 100% accuracy for diagnosing chromosomal abnormalities<\/li>\n\n\n\n<li>Detects microdeletion syndromes (e.g., 22q11.2 deletion) and structural anomalies<\/li>\n<\/ul>\n\n\n\n<p><strong>Risks<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Miscarriage risk of 0.1\u20130.3%<\/li>\n\n\n\n<li>Possible complications such as infection or bleeding<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Key_Points_for_Consulting_Physicians\"><\/span>Key Points for Consulting Physicians<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Decisions on retesting should consider:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> coverage and results<\/li>\n\n\n\n<li>Ultrasound findings<\/li>\n\n\n\n<li>Fetal cfDNA fraction<\/li>\n\n\n\n<li>Family history or genetic background<\/li>\n\n\n\n<li>Psychological needs of the parents<\/li>\n<\/ul>\n\n\n\n<p>Doctors typically follow guidelines from the <strong>Japan Society of Obstetrics and Gynecology (JSOG)<\/strong> and the <strong>Japan Society of Human Genetics<\/strong>.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/nipt\/wp-content\/uploads\/2025\/09\/24914789_s.webp\" alt=\"\u533b\u8005\" class=\"wp-image-116189\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Expert_Perspective_Negative_%E2%89%A0_Absolute_Reassurance\"><\/span>Expert Perspective: Negative \u2260 Absolute Reassurance<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>A 2022 study from Nippon Medical School reported chromosomal abnormalities confirmed after birth in some <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>-negative cases, underscoring the need for cautious interpretation and multifactorial decision-making.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Importance_of_Genetic_Counseling\"><\/span>Importance of Genetic Counseling<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Genetic counseling ensures accurate understanding of:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>The real meaning of negative results (not equal to \u201cno abnormalities\u201d)<\/li>\n\n\n\n<li>False negative risks<\/li>\n\n\n\n<li>Options for future pregnancy management<\/li>\n\n\n\n<li>Ethical considerations and family decision-making<\/li>\n<\/ul>\n\n\n\n<p>This process supports <strong>informed choice<\/strong>, which is central to prenatal care.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Misconceptions_and_Clarifications\"><\/span>Misconceptions and Clarifications<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Myth 1<\/strong>: Negative = absolutely healthy fetus<br>\u2192 False. <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> only screens for major trisomies, not sex chromosome disorders, microdeletions, or structural anomalies.<\/li>\n\n\n\n<li><strong>Myth 2<\/strong>: Retesting is only for positive results<br>\u2192 False. If ultrasound shows abnormalities, retesting (amniocentesis) may be advised even after a negative <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"International_Guidelines\"><\/span>International Guidelines<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>ACOG (American College of Obstetricians and Gynecologists)<\/strong>: Recommends considering diagnostic testing regardless of <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> results if ultrasound abnormalities or maternal risk factors exist.<\/li>\n\n\n\n<li><strong>NICE (UK National Institute for Health and Care Excellence)<\/strong>: States that additional testing should be offered if ultrasound anomalies are present, even with negative <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Clinical_Case_Example\"><\/span>Clinical Case Example<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>At a Japanese university hospital, a woman with negative <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> was later found at 20 weeks ultrasound to have a fetus with severe congenital heart defect. Amniocentesis confirmed 22q11.2 deletion syndrome, which <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> does not cover.<\/p>\n\n\n\n<p>This case highlights the importance of combining ultrasound findings with diagnostic testing for accurate outcomes.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cost_and_Psychological_Considerations\"><\/span>Cost and Psychological Considerations<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Cost<\/strong>: Amniocentesis is usually not covered by insurance, costing \u00a580,000\u2013150,000 ($600\u20131,200).<\/li>\n\n\n\n<li><strong>Psychological impact<\/strong>: While more testing can increase anxiety, definitive results may provide reassurance and allow better preparation for delivery and care.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"FAQs\"><\/span>FAQs<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>Q1: <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> was negative, but ultrasound showed abnormalities. What should I do?<\/strong><br>\u2192 Consult your doctor or genetic counselor about options, including amniocentesis.<\/p>\n\n\n\n<p><strong>Q2: Is retesting (amniocentesis) covered by insurance?<\/strong><br>\u2192 Most are self-paid, but specific conditions may be partially covered if deemed medically necessary.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Conclusion_Negative_NIPT_Does_Not_Eliminate_the_Need_for_Retesting\"><\/span>Conclusion: Negative NIPT Does Not Eliminate the Need for Retesting<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>While a negative <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> result is highly reliable, it is not absolute. Depending on pregnancy progression and additional findings, diagnostic testing such as amniocentesis may be necessary.<\/p>\n\n\n\n<p>A comprehensive approach combining <strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> + ultrasound + genetic counseling<\/strong> offers the safest and most reliable pregnancy care.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"Introduction NIPT (N&#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt-negative-amniocentesis\/?lang=en\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":122,"featured_media":116334,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[97],"tags":[],"class_list":["post-116933","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/116933","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/122"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=116933"}],"version-history":[{"count":3,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/116933\/revisions"}],"predecessor-version":[{"id":118144,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/116933\/revisions\/118144"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/116334"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=116933"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=116933"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=116933"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}