{"id":116949,"date":"2025-09-29T17:17:48","date_gmt":"2025-09-29T08:17:48","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/"},"modified":"2025-10-15T15:09:15","modified_gmt":"2025-10-15T06:09:15","slug":"prenatal-testing-nipt-results","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en","title":{"rendered":"What Can Prenatal Testing Reveal? \u2014 Chromosomal Abnormalities and Fetal Sex"},"content":{"rendered":"\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#What_is_NIPT\" >What is NIPT?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Chromosomal_Abnormalities_Detectable_by_NIPT\" >Chromosomal Abnormalities Detectable by NIPT<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Can_NIPT_Determine_Sex\" >Can NIPT Determine Sex?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Mechanism_and_Accuracy_of_NIPT\" >Mechanism and Accuracy of NIPT<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Positive_%E2%89%A0_Diagnosis_False_Positives_and_Negatives\" >Positive \u2260 Diagnosis: False Positives and Negatives<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#NIPT_in_Japan_Testing_Types_and_Conditions\" >NIPT in Japan: Testing Types and Conditions<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Benefits_and_Challenges_of_NIPT\" >Benefits and Challenges of NIPT<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Expanding_Scope_of_NIPT\" >Expanding Scope of NIPT<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Key_Considerations_Before_Testing\" >Key Considerations Before Testing<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Global_Trends_vs_Japan\" >Global Trends vs. Japan<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Frequently_Asked_Questions_FAQ\" >Frequently Asked Questions (FAQ)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\/#Conclusion_Understand_NIPT_Correctly_Choose_Wisely\" >Conclusion: Understand NIPT Correctly, Choose Wisely<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_is_NIPT\"><\/span>What is NIPT?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>In recent years, <strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> (Non-Invasive Prenatal Testing)<\/strong> has been gaining significant attention among expectant mothers.<br><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> analyzes fetal DNA fragments in the mother\u2019s blood to screen for chromosomal abnormalities such as <strong>Down syndrome (trisomy 21)<\/strong> with high accuracy.<\/p>\n\n\n\n<p>Compared to traditional prenatal testing, <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> poses minimal risk to both mother and fetus. It can be performed from the 10th week of pregnancy and has rapidly spread as a new screening option.<\/p>\n\n\n\n<p>This article answers the question: <strong>\u201cWhat can <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> detect?\u201d<\/strong> We will explain its mechanism, detectable chromosomal abnormalities, whether sex determination is possible, accuracy, and important considerations.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Chromosomal_Abnormalities_Detectable_by_NIPT\"><\/span>Chromosomal Abnormalities Detectable by NIPT<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Trisomy 21 (Down syndrome)<\/strong><br>The most common abnormality, caused by an extra 21st chromosome. Often associated with intellectual disability, characteristic facial features, and congenital heart disease.<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Prevalence: ~1 in 700<\/li>\n\n\n\n<li>Sensitivity: \u226599%<\/li>\n\n\n\n<li>Specificity: \u226599%<br>(Source: Gil et al., 2015)<\/li>\n<\/ul>\n\n\n\n<ol start=\"2\" class=\"wp-block-list\">\n<li><strong>Trisomy 18 (Edwards syndrome)<\/strong><br>Caused by an extra 18th chromosome. Leads to severe growth restriction, heart defects, and usually results in fetal or neonatal death.<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Prevalence: ~1 in 5,000<\/li>\n\n\n\n<li>Sensitivity: 97\u201399%<\/li>\n\n\n\n<li>Specificity: \u226599%<\/li>\n<\/ul>\n\n\n\n<ol start=\"3\" class=\"wp-block-list\">\n<li><strong>Trisomy 13 (Patau syndrome)<\/strong><br>Caused by an extra 13th chromosome. Associated with severe brain and heart malformations, with very poor prognosis.<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Prevalence: ~1 in 10,000<\/li>\n\n\n\n<li>Sensitivity: 91\u201396%<\/li>\n\n\n\n<li>Specificity: \u226599%<\/li>\n<\/ul>\n\n\n\n<ol start=\"4\" class=\"wp-block-list\">\n<li><strong>Sex Chromosome Abnormalities (optional depending on facility)<\/strong><br>Examples include:<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Turner syndrome (45,X)<\/li>\n\n\n\n<li>Klinefelter syndrome (47,XXY)<\/li>\n\n\n\n<li>Jacob\u2019s syndrome (47,XYY)<\/li>\n<\/ul>\n\n\n\n<p>\u203b These do not always cause severe symptoms. Whether to test should be discussed with a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Can_NIPT_Determine_Sex\"><\/span>Can NIPT Determine Sex?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Yes. <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> can identify fetal sex with high accuracy by detecting the presence of a <strong>Y chromosome<\/strong> in maternal blood.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Y chromosome present \u2192 male<\/li>\n\n\n\n<li>No Y chromosome \u2192 female<\/li>\n<\/ul>\n\n\n\n<p>However, in Japan, many facilities do not disclose fetal sex results, and <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is not offered solely for sex determination.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Mechanism_and_Accuracy_of_NIPT\"><\/span>Mechanism and Accuracy of NIPT<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Principle<\/strong>: From the 10th week of pregnancy, a small fraction (~10%) of cell-free fetal DNA (cfDNA), derived from the placenta, circulates in maternal blood. <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> extracts and analyzes this cfDNA using next-generation sequencing (NGS) to detect chromosomal imbalances.<\/li>\n\n\n\n<li><strong>Accuracy<\/strong>: <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is a <strong>highly accurate screening test<\/strong>, but not a diagnostic test. A positive result requires confirmatory testing via amniocentesis or chorionic villus sampling.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Positive_%E2%89%A0_Diagnosis_False_Positives_and_Negatives\"><\/span>Positive \u2260 Diagnosis: False Positives and Negatives<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>False positives<\/strong>: Caused by placental mosaicism or DNA abnormalities.<\/li>\n\n\n\n<li><strong>False negatives<\/strong>: May occur due to insufficient fetal cfDNA concentration or rare abnormalities.<\/li>\n\n\n\n<li><strong>Multiple pregnancies (twins, etc.)<\/strong>: Lower accuracy, sometimes excluded.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"NIPT_in_Japan_Testing_Types_and_Conditions\"><\/span>NIPT in Japan: Testing Types and Conditions<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Clinical Research Model (Certified Facilities)<\/strong><\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Target: Pregnant women \u226535 or those at high risk<\/li>\n\n\n\n<li>Cost: ~\u00a5150,000\u2013\u00a5200,000<\/li>\n\n\n\n<li>Fetal sex and sex chromosome results: Generally not disclosed<\/li>\n<\/ul>\n\n\n\n<ol start=\"2\" class=\"wp-block-list\">\n<li><strong>Private Clinics (Non-certified, self-funded)<\/strong><\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Target: No age restrictions (available to women in their 20s)<\/li>\n\n\n\n<li>Cost: ~\u00a580,000\u2013\u00a5150,000<\/li>\n\n\n\n<li>Fetal sex and sex chromosome abnormalities: Sometimes disclosed<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Benefits_and_Challenges_of_NIPT\"><\/span>Benefits and Challenges of NIPT<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>Benefits<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>High accuracy, non-invasive, minimal risk<\/li>\n\n\n\n<li>Available from early pregnancy (10 weeks onward)<\/li>\n\n\n\n<li>Enables early confirmatory testing if positive<\/li>\n<\/ul>\n\n\n\n<p><strong>Challenges \/ Ethical Issues<\/strong><\/p>\n\n\n\n<p>Importance of genetic counseling<\/p>\n\n\n\n<p>Potential link to selective abortion \u2192 eugenics concerns<\/p>\n\n\n\n<p>Handling sensitive information (sex selection, discrimination)<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"426\" src=\"\/nipt\/wp-content\/uploads\/2025\/09\/33435182_s-1.webp\" alt=\"\u533b\u8005\" class=\"wp-image-116941\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Expanding_Scope_of_NIPT\"><\/span>Expanding Scope of NIPT<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>With technological advances, some facilities now screen for microdeletion syndromes, such as:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>22q11.2 Deletion Syndrome (DiGeorge Syndrome)<\/strong><br>Associated with congenital heart disease, immune deficiency, and developmental delay.<\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Prevalence: ~1 in 2,000\u20134,000<\/li>\n\n\n\n<li>Sensitivity\/specificity: Varies; some studies report \u226590%<\/li>\n<\/ul>\n\n\n\n<ol start=\"2\" class=\"wp-block-list\">\n<li><strong>Other examples<\/strong><\/li>\n<\/ol>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Cri-du-chat syndrome (5p deletion)<\/li>\n\n\n\n<li><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/1p-36-deletion-syndrome\/\">1p36<\/a> deletion syndrome<\/li>\n\n\n\n<li>Angelman syndrome \/ Prader-Willi syndrome (15q-related)<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Key_Considerations_Before_Testing\"><\/span>Key Considerations Before Testing<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Timing<\/strong>: Most <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is performed at \u226510 weeks gestation.<\/li>\n\n\n\n<li><strong>Sample &amp; turnaround time<\/strong>: ~10ml blood sample; results in ~1 week. Some clinics offer expedited options.<\/li>\n\n\n\n<li><strong>Pre- and post-test counseling<\/strong>: Essential to discuss testing goals and possible responses to a positive result with family and doctors.<\/li>\n<\/ol>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Global_Trends_vs_Japan\"><\/span>Global Trends vs. Japan<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Overseas<\/strong>: Widely available in the US, UK, and other countries. In some regions, insurance covers part or all of the cost. Commercial labs offer expanded genetic testing.<\/li>\n\n\n\n<li><strong>Japan<\/strong>: Still mainly self-funded; access and cost vary. Growth of non-certified clinics has raised concerns over inadequate counseling. The Japan Society of Obstetrics and Gynecology has revised guidelines to emphasize ethics and accurate information sharing.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Frequently_Asked_Questions_FAQ\"><\/span>Frequently Asked Questions (FAQ)<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><strong>Q1. Does <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> detect all fetal abnormalities?<\/strong><br>\u2192 No. It is a screening test. Positive results require confirmatory testing.<\/p>\n\n\n\n<p><strong>Q2. Is it meaningful for young women to take <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>?<\/strong><br>\u2192 Yes. While risk increases with maternal age, younger women are not risk-free. Many in their 20s also seek reassurance through testing.<\/p>\n\n\n\n<p><strong>Q3. How are results delivered?<\/strong><br>\u2192 Typically via in-person or online consultation with a doctor. Solely mailing or emailing results may lead to insufficient explanation.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Conclusion_Understand_NIPT_Correctly_Choose_Wisely\"><\/span>Conclusion: Understand NIPT Correctly, Choose Wisely<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> is a high-accuracy screening, not a diagnosis<\/li>\n\n\n\n<li>Knowledge of chromosomal and sex chromosome abnormalities, as well as microdeletions, is essential<\/li>\n\n\n\n<li>Counseling with medical professionals is indispensable<\/li>\n\n\n\n<li>Clear testing goals and ethical considerations are necessary<\/li>\n<\/ul>\n\n\n\n<p>Used appropriately, <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> can serve as a reliable tool for reassurance and informed decision-making \u2014 setting a new standard for prenatal testing.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"What is NIPT? In rec&#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/prenatal-testing-nipt-results\/?lang=en\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":122,"featured_media":116101,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[97],"tags":[],"class_list":["post-116949","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/116949","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/122"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=116949"}],"version-history":[{"count":3,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/116949\/revisions"}],"predecessor-version":[{"id":118166,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/116949\/revisions\/118166"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/116101"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=116949"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=116949"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=116949"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}