{"id":121854,"date":"2026-01-07T17:47:02","date_gmt":"2026-01-07T08:47:02","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?p=121854"},"modified":"2026-01-07T17:47:04","modified_gmt":"2026-01-07T08:47:04","slug":"angelman-syndrome-comprehensive-guide","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/","title":{"rendered":"\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4"},"content":{"rendered":"\n<p>\u304a\u5b50\u69d8\u304c\u300c\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\u300d\u3068\u3044\u3046\u8a3a\u65ad\u3092\u53d7\u3051\u305f\u3068\u304d\u3001\u3042\u308b\u3044\u306f\u305d\u306e\u7591\u3044\u304c\u3042\u308b\u3068\u8a00\u308f\u308c\u305f\u3068\u304d\u3001\u591a\u304f\u306e\u3054\u5bb6\u65cf\u306f\u300c\u805e\u3044\u305f\u3053\u3068\u3082\u306a\u3044\u75c5\u540d\u3060\u300d\u300c\u3053\u308c\u304b\u3089\u3069\u3046\u306a\u3063\u3066\u3057\u307e\u3046\u3093\u3060\u308d\u3046\u300d\u3068\u3001\u6df1\u3044\u4e0d\u5b89\u3068\u6df7\u4e71\u306e\u4e2d\u306b\u7f6e\u304b\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u3067\u691c\u7d22\u3059\u308b\u3068\u3001\u53e4\u3044\u60c5\u5831\u3084\u96e3\u3057\u3044\u533b\u5b66\u7528\u8a9e\u3070\u304b\u308a\u304c\u51fa\u3066\u304d\u3066\u3001\u4f59\u8a08\u306b\u6016\u304f\u306a\u3063\u3066\u3057\u307e\u3063\u305f\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\u306e\u304a\u5b50\u69d8\u305f\u3061\u306f\u3001\u305d\u306e\u7279\u6027\u3086\u3048\u306b\u5468\u56f2\u306e\u4eba\u3005\u3092\u81ea\u7136\u3068\u7b11\u9854\u306b\u3059\u308b\u3001\u4e0d\u601d\u8b70\u306a\u9b45\u529b\u3068\u611b\u3089\u3057\u3055\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u533b\u5b66\u7684\u306a\u77e5\u8b58\u304c\u306a\u3044\u65b9\u3067\u3082\u7406\u89e3\u3067\u304d\u308b\u3088\u3046\u3001\u3053\u306e\u75c5\u6c17\u306e\u6b63\u4f53\u3001\u4e88\u60f3\u3055\u308c\u308b\u75c7\u72b6\u3001\u6700\u65b0\u306e\u907a\u4f1d\u5b66\u7684\u80cc\u666f\u3001\u305d\u3057\u3066\u3053\u308c\u304b\u3089\u306e\u751f\u6d3b\u3067\u5927\u5207\u306b\u3057\u3066\u307b\u3057\u3044\u3053\u3068\u3092\u3001\u4e01\u5be7\u306b\u89e3\u8aac\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" 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href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E3%80%8C%E7%AC%91%E9%A1%94%E3%80%8D%E3%81%8C%E7%89%B9%E5%BE%B4%E7%9A%84%E3%81%AA%E7%96%BE%E6%82%A3\" >\u300c\u7b11\u9854\u300d\u304c\u7279\u5fb4\u7684\u306a\u75be\u60a3<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E4%B8%BB%E3%81%AA%E7%97%87%E7%8A%B6\" >\u4e3b\u306a\u75c7\u72b6<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#1_%E3%81%99%E3%81%B9%E3%81%A6%E3%81%AE%E6%82%A3%E8%80%85%E3%81%95%E3%82%93%E3%81%AB%E8%A6%8B%E3%82%89%E3%82%8C%E3%82%8B%E7%89%B9%E5%BE%B4%EF%BC%88100%EF%BC%89\" >1. \u3059\u3079\u3066\u306e\u60a3\u8005\u3055\u3093\u306b\u898b\u3089\u308c\u308b\u7279\u5fb4\uff08100%\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#2_%E5%A4%9A%E3%81%8F%E3%81%AE%E6%82%A3%E8%80%85%E3%81%95%E3%82%93%E3%81%AB%E8%A6%8B%E3%82%89%E3%82%8C%E3%82%8B%E7%89%B9%E5%BE%B4%EF%BC%8880%E4%BB%A5%E4%B8%8A%EF%BC%89\" >2. \u591a\u304f\u306e\u60a3\u8005\u3055\u3093\u306b\u898b\u3089\u308c\u308b\u7279\u5fb4\uff0880%\u4ee5\u4e0a\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#3_%E3%81%9D%E3%81%AE%E4%BB%96%E3%80%81%E3%82%88%E3%81%8F%E8%A6%8B%E3%82%89%E3%82%8C%E3%82%8B%E7%89%B9%E5%BE%B4%EF%BC%8820%E3%80%9C80%EF%BC%89\" >3. \u305d\u306e\u4ed6\u3001\u3088\u304f\u898b\u3089\u308c\u308b\u7279\u5fb4\uff0820\u301c80%\uff09<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E5%8E%9F%E5%9B%A0%EF%BC%9A15%E7%95%AA%E6%9F%93%E8%89%B2%E4%BD%93%E3%81%AE%E4%B8%8D%E6%80%9D%E8%AD%B0\" >\u539f\u56e0\uff1a15\u756a\u67d3\u8272\u4f53\u306e\u4e0d\u601d\u8b70<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E3%80%8C%E6%AF%8D%E7%94%B1%E6%9D%A5%E3%80%8D%E3%81%A0%E3%81%91%E3%81%8C%E5%83%8D%E3%81%8F%E3%83%AB%E3%83%BC%E3%83%AB\" >\u300c\u6bcd\u7531\u6765\u300d\u3060\u3051\u304c\u50cd\u304f\u30eb\u30fc\u30eb<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E5%8E%9F%E5%9B%A0%E3%81%A8%E3%81%AA%E3%82%8B4%E3%81%A4%E3%81%AE%E3%82%BF%E3%82%A4%E3%83%97\" >\u539f\u56e0\u3068\u306a\u308b4\u3064\u306e\u30bf\u30a4\u30d7<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E8%A8%BA%E6%96%AD%E3%81%A8%E6%A4%9C%E6%9F%BB\" >\u8a3a\u65ad\u3068\u691c\u67fb<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#1_%E8%84%B3%E6%B3%A2%E6%A4%9C%E6%9F%BB\" >1. \u8133\u6ce2\u691c\u67fb<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#2_%E9%81%BA%E4%BC%9D%E5%AD%A6%E7%9A%84%E6%A4%9C%E6%9F%BB%EF%BC%88%E7%A2%BA%E5%AE%9A%E8%A8%BA%E6%96%AD%EF%BC%89\" >2. \u907a\u4f1d\u5b66\u7684\u691c\u67fb\uff08\u78ba\u5b9a\u8a3a\u65ad\uff09<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E6%B2%BB%E7%99%82%E3%81%A8%E7%AE%A1%E7%90%86\" >\u6cbb\u7642\u3068\u7ba1\u7406<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#1_%E3%81%A6%E3%82%93%E3%81%8B%E3%82%93%E3%81%AE%E7%AE%A1%E7%90%86\" >1. \u3066\u3093\u304b\u3093\u306e\u7ba1\u7406<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#2_%E7%9D%A1%E7%9C%A0%E9%9A%9C%E5%AE%B3%E3%81%AE%E5%AF%BE%E5%BF%9C\" >2. \u7761\u7720\u969c\u5bb3\u306e\u5bfe\u5fdc<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#3_%E9%81%8B%E5%8B%95%E3%83%BB%E8%BA%AB%E4%BD%93%E9%9D%A2%E3%81%AE%E3%82%B1%E3%82%A2\" >3. \u904b\u52d5\u30fb\u8eab\u4f53\u9762\u306e\u30b1\u30a2<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#4_%E3%82%B3%E3%83%9F%E3%83%A5%E3%83%8B%E3%82%B1%E3%83%BC%E3%82%B7%E3%83%A7%E3%83%B3%E6%94%AF%E6%8F%B4%EF%BC%88%E8%A8%80%E8%AA%9E%E8%81%B4%E8%A6%9A%E7%99%82%E6%B3%95%EF%BC%9AST%EF%BC%89\" >4. \u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u652f\u63f4\uff08\u8a00\u8a9e\u8074\u899a\u7642\u6cd5\uff1aST\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#5_%E9%A3%9F%E4%BA%8B%E3%83%BB%E6%B6%88%E5%8C%96%E5%99%A8%E3%81%AE%E3%82%B1%E3%82%A2\" >5. \u98df\u4e8b\u30fb\u6d88\u5316\u5668\u306e\u30b1\u30a2<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E8%87%A8%E5%BA%8A%E8%A9%A6%E9%A8%93%E3%81%A8%E7%A0%94%E7%A9%B6%E3%81%AE%E6%9C%80%E5%89%8D%E7%B7%9A%EF%BC%88%E5%B8%8C%E6%9C%9B%E3%81%AE%E5%85%89%EF%BC%89\" >\u81e8\u5e8a\u8a66\u9a13\u3068\u7814\u7a76\u306e\u6700\u524d\u7dda\uff08\u5e0c\u671b\u306e\u5149\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E6%97%A5%E3%80%85%E3%81%AE%E7%94%9F%E6%B4%BB%E3%81%A7%E3%81%AE%E6%B3%A8%E6%84%8F%E7%82%B9\" >\u65e5\u3005\u306e\u751f\u6d3b\u3067\u306e\u6ce8\u610f\u70b9<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E3%81%BE%E3%81%A8%E3%82%81\" >\u307e\u3068\u3081<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E5%AE%B6%E6%97%8F%E3%81%B8%E3%81%AE%E3%83%A1%E3%83%83%E3%82%BB%E3%83%BC%E3%82%B8\" >\u5bb6\u65cf\u3078\u306e\u30e1\u30c3\u30bb\u30fc\u30b8<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/angelman-syndrome-comprehensive-guide\/#%E6%AC%A1%E3%81%AE%E3%82%A2%E3%82%AF%E3%82%B7%E3%83%A7%E3%83%B3\" >\u6b21\u306e\u30a2\u30af\u30b7\u30e7\u30f3<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%A6%82%E8%A6%81%EF%BC%9A%E3%81%A9%E3%81%AE%E3%82%88%E3%81%86%E3%81%AA%E7%97%85%E6%B0%97%E3%81%8B\"><\/span><strong>\u6982\u8981\uff1a\u3069\u306e\u3088\u3046\u306a\u75c5\u6c17\u304b<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\uff08Angelman syndrome: AS\uff09\u306f\u300115\u756a\u67d3\u8272\u4f53\u306b\u3042\u308b\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u304c\u5931\u308f\u308c\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u8d77\u3053\u308b\u3001\u751f\u307e\u308c\u3064\u304d\u306e\u795e\u7d4c\u767a\u9054\u75c7\uff08\u767a\u9054\u969c\u5bb3\uff09\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%80%8C%E7%AC%91%E9%A1%94%E3%80%8D%E3%81%8C%E7%89%B9%E5%BE%B4%E7%9A%84%E3%81%AA%E7%96%BE%E6%82%A3\"><\/span><strong>\u300c\u7b11\u9854\u300d\u304c\u7279\u5fb4\u7684\u306a\u75be\u60a3<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>1965\u5e74\u3001\u30a4\u30ae\u30ea\u30b9\u306e\u5c0f\u5150\u79d1\u533b\u30cf\u30ea\u30fc\u30fb\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u535a\u58eb\u306b\u3088\u3063\u3066\u521d\u3081\u3066\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u75c5\u6c17\u306e\u6700\u5927\u306e\u7279\u5fb4\u306f\u3001\u300c\u3088\u304f\u7b11\u3044\u3001\u7b11\u9854\u304c\u7d76\u3048\u306a\u3044\u300d\u3053\u3068\u3001\u305d\u3057\u3066\u300c\u4eba\u61d0\u3063\u3053\u304f\u3001\u6c34\u3092\u597d\u3080\u300d**\u3068\u3044\u3063\u305f\u72ec\u7279\u306e\u884c\u52d5\u7279\u6027\u306b\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u69d8\u5b50\u304b\u3089\u3001\u304b\u3064\u3066\u306f\u300c\u30cf\u30c3\u30d4\u30fc\u30fb\u30d1\u30da\u30c3\u30c8\uff08\u5e78\u305b\u306a\u64cd\u308a\u4eba\u5f62\uff09\u75c7\u5019\u7fa4\u300d\u3068\u547c\u3070\u308c\u305f\u3053\u3068\u3082\u3042\u308a\u307e\u3057\u305f\u304c\u3001\u73fe\u5728\u306f\u8511\u79f0\u3068\u6349\u3048\u3089\u308c\u308b\u305f\u3081\u4f7f\u308f\u308c\u307e\u305b\u3093\u3002\u4ee3\u308f\u308a\u306b\u3001\u305d\u306e\u611b\u3089\u3057\u3044\u69d8\u5b50\u304b\u3089\u300c\u30a8\u30f3\u30b8\u30a7\u30eb\uff08\u5929\u4f7f\uff09\u300d\u306e\u30a4\u30e1\u30fc\u30b8\u3068\u91cd\u306d\u3066\u8a9e\u3089\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u767a\u751f\u983b\u5ea6:<\/strong> \u7d0415,000\u4eba\u301c20,000\u4eba\u306b1\u4eba\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7537\u5973\u5dee\u3084\u4eba\u7a2e\u5dee\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/li>\n\n\n\n<li><strong>\u5bff\u547d:<\/strong> \u57fa\u672c\u7684\u306b\u5065\u5eb7\u306a\u4eba\u3068\u5909\u308f\u3089\u305a\u3001\u5929\u5bff\u3092\u5168\u3046\u3067\u304d\u308b\u75be\u60a3\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u6307\u5b9a\u96e3\u75c5:<\/strong> \u65e5\u672c\u3067\u306f\u56fd\u306e\u6307\u5b9a\u96e3\u75c5\uff08\u544a\u793a\u756a\u53f7201\uff09\u304a\u3088\u3073\u5c0f\u5150\u6162\u6027\u7279\u5b9a\u75be\u75c5\u306b\u6307\u5b9a\u3055\u308c\u3066\u304a\u308a\u3001\u533b\u7642\u8cbb\u306e\u52a9\u6210\u5bfe\u8c61\u3068\u306a\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%BB%E3%81%AA%E7%97%87%E7%8A%B6\"><\/span><strong>\u4e3b\u306a\u75c7\u72b6<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\u306e\u75c7\u72b6\u306f\u3001\u5e74\u9f62\u3068\u3068\u3082\u306b\u5909\u5316\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u500b\u4eba\u5dee\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u975e\u5e38\u306b\u9ad8\u3044\u78ba\u7387\uff08\u307b\u307c100%\uff09\u3067\u898b\u3089\u308c\u308b\u75c7\u72b6\u3068\u3001\u4eba\u306b\u3088\u3063\u3066\u898b\u3089\u308c\u308b\u75c7\u72b6\u306b\u5206\u3051\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_%E3%81%99%E3%81%B9%E3%81%A6%E3%81%AE%E6%82%A3%E8%80%85%E3%81%95%E3%82%93%E3%81%AB%E8%A6%8B%E3%82%89%E3%82%8C%E3%82%8B%E7%89%B9%E5%BE%B4%EF%BC%88100%EF%BC%89\"><\/span><strong>1. \u3059\u3079\u3066\u306e\u60a3\u8005\u3055\u3093\u306b\u898b\u3089\u308c\u308b\u7279\u5fb4\uff08100%\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u91cd\u5ea6\u306e\u767a\u9054\u306e\u9045\u308c:<br>\u9996\u306e\u3059\u308f\u308a\u3001\u304a\u5ea7\u308a\u3001\u30cf\u30a4\u30cf\u30a4\u3001\u6b69\u884c\u306a\u3069\u306e\u904b\u52d5\u767a\u9054\u304c\u3086\u3063\u304f\u308a\u3067\u3059\u3002<\/li>\n\n\n\n<li>\u8a00\u8449\u306e\u9045\u308c\uff08\u767a\u8a9e\u304c\u306a\u3044\uff09:<br>\u8a00\u8449\u306e\u7406\u89e3\u529b\uff08\u8a00\u3063\u3066\u3044\u308b\u3053\u3068\u306f\u5206\u304b\u308b\uff09\u306b\u6bd4\u3079\u3001\u8a00\u8449\u3092\u8a71\u3059\u529b\uff08\u8868\u51fa\uff09\u304c\u5f31\u3044\u3067\u3059\u3002\u610f\u5473\u306e\u3042\u308b\u5358\u8a9e\u3092\u6570\u8a9e\u8a71\u305b\u308b\u5b50\u3082\u3044\u307e\u3059\u304c\u3001\u5168\u304f\u8a71\u3055\u306a\u3044\u30b1\u30fc\u30b9\u3082\u591a\u3044\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u30b8\u30a7\u30b9\u30c1\u30e3\u30fc\u3084\u8868\u60c5\u3067\u306e\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u306f\u975e\u5e38\u306b\u8c4a\u304b\u3067\u3059\u3002<\/li>\n\n\n\n<li>\u904b\u52d5\u30fb\u30d0\u30e9\u30f3\u30b9\u306e\u969c\u5bb3\uff08\u5931\u8abf\uff09:<br>\u6b69\u304f\u3068\u304d\u306b\u8db3\u3092\u958b\u3044\u3066\u30d0\u30e9\u30f3\u30b9\u3092\u53d6\u308a\u306a\u304c\u3089\u6b69\u304f\uff08\u5931\u8abf\u6027\u6b69\u884c\uff09\u3001\u624b\u304c\u5c0f\u523b\u307f\u306b\u9707\u3048\u308b\u3001\u304e\u3053\u3061\u306a\u3044\u52d5\u304d\u3092\u3059\u308b\u306a\u3069\u306e\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li>\u72ec\u7279\u306e\u884c\u52d5\u7279\u6027:<br>\u983b\u7e41\u306b\u7b11\u3046\u3001\u58f0\u3092\u7acb\u3066\u3066\u7b11\u3046\u3001\u5e38\u306b\u6a5f\u5acc\u304c\u826f\u3044\u3001\u624b\u3092\u30d1\u30bf\u30d1\u30bf\u3055\u305b\u308b\u3001\u8208\u596e\u3057\u3084\u3059\u3044\u3001\u6ce8\u610f\u304c\u79fb\u308a\u3084\u3059\u3044\uff08\u591a\u52d5\u50be\u5411\uff09\u306a\u3069\u304c\u898b\u3089\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_%E5%A4%9A%E3%81%8F%E3%81%AE%E6%82%A3%E8%80%85%E3%81%95%E3%82%93%E3%81%AB%E8%A6%8B%E3%82%89%E3%82%8C%E3%82%8B%E7%89%B9%E5%BE%B4%EF%BC%8880%E4%BB%A5%E4%B8%8A%EF%BC%89\"><\/span><strong>2. \u591a\u304f\u306e\u60a3\u8005\u3055\u3093\u306b\u898b\u3089\u308c\u308b\u7279\u5fb4\uff0880%\u4ee5\u4e0a\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5c0f\u982d\u75c7\uff08\u3057\u3087\u3046\u3068\u3046\u3057\u3087\u3046\uff09:<br>\u751f\u307e\u308c\u305f\u6642\u306e\u982d\u306e\u5927\u304d\u3055\u306f\u6b63\u5e38\u3067\u3059\u304c\u30012\u6b73\u9803\u304b\u3089\u982d\u306e\u6210\u9577\u304c\u7de9\u3084\u304b\u306b\u306a\u308a\u3001\u982d\u56f2\u304c\u5e73\u5747\u3088\u308a\u5c0f\u3055\u304f\u306a\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li>\u3066\u3093\u304b\u3093\u767a\u4f5c:<br>3\u6b73\u9803\u307e\u3067\u306b\u7d0480\u301c90%\u306e\u304a\u5b50\u69d8\u3067\u767a\u75c7\u3057\u307e\u3059\u3002\u767a\u4f5c\u306e\u30bf\u30a4\u30d7\u306f\u69d8\u3005\u3067\u3059\u304c\u3001\u5e74\u9f62\u3068\u3068\u3082\u306b\u983b\u5ea6\u306f\u6e1b\u308a\u3001\u601d\u6625\u671f\u4ee5\u964d\u306f\u843d\u3061\u7740\u304f\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/li>\n\n\n\n<li>\u7279\u5fb4\u7684\u306a\u8133\u6ce2\u7570\u5e38:<br>\u3066\u3093\u304b\u3093\u767a\u4f5c\u304c\u306a\u304f\u3066\u3082\u3001\u8133\u6ce2\u691c\u67fb\u3092\u3059\u308b\u3068\u975e\u5e38\u306b\u7279\u5fb4\u7684\u306a\u6ce2\u5f62\uff08\u4e09\u76f8\u6027\u6ce2\u306a\u3069\uff09\u304c\u898b\u3089\u308c\u3001\u8a3a\u65ad\u306e\u5927\u304d\u306a\u624b\u52a9\u3051\u306b\u306a\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_%E3%81%9D%E3%81%AE%E4%BB%96%E3%80%81%E3%82%88%E3%81%8F%E8%A6%8B%E3%82%89%E3%82%8C%E3%82%8B%E7%89%B9%E5%BE%B4%EF%BC%8820%E3%80%9C80%EF%BC%89\"><\/span><strong>3. \u305d\u306e\u4ed6\u3001\u3088\u304f\u898b\u3089\u308c\u308b\u7279\u5fb4\uff0820\u301c80%\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u7761\u7720\u969c\u5bb3:<br>\u5bdd\u4ed8\u304d\u304c\u60aa\u3044\u3001\u591c\u4e2d\u306b\u4f55\u5ea6\u3082\u8d77\u304d\u308b\u3001\u7761\u7720\u6642\u9593\u304c\u77ed\u3044\u306a\u3069\u3002\u3054\u5bb6\u65cf\u306b\u3068\u3063\u3066\u5927\u304d\u306a\u8ca0\u62c5\u3068\u306a\u308b\u3053\u3068\u304c\u591a\u3044\u75c7\u72b6\u3067\u3059\u3002<\/li>\n\n\n\n<li>\u6c34\u3078\u306e\u5f37\u3044\u8208\u5473:<br>\u6c34\u904a\u3073\u304c\u5927\u597d\u304d\u3067\u3001\u86c7\u53e3\u306e\u6c34\u3084\u30d7\u30fc\u30eb\u3001\u6c34\u305f\u307e\u308a\u306a\u3069\u306b\u7570\u5e38\u306a\u307b\u3069\u60f9\u304d\u3064\u3051\u3089\u308c\u307e\u3059\u3002<\/li>\n\n\n\n<li>\u53e3\u5143\u306e\u7279\u5fb4:<br>\u53e3\u304c\u5927\u304d\u3044\u3001\u6b6f\u306e\u9593\u304c\u958b\u3044\u3066\u3044\u308b\uff08\u3059\u304d\u3063\u6b6f\uff09\u3001\u820c\u3092\u51fa\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u3044\u3001\u3088\u3060\u308c\u304c\u591a\u3044\u3001\u7269\u3092\u565b\u3080\u306e\u304c\u597d\u304d\u306a\u3069\u3002<\/li>\n\n\n\n<li>\u8272\u7d20\u304c\u8584\u3044:<br>\u907a\u4f1d\u5b50\u306e\u30bf\u30a4\u30d7\u306b\u3088\u3063\u3066\u306f\u3001\u5bb6\u65cf\u306b\u6bd4\u3079\u3066\u9aea\u3084\u76ae\u819a\u3001\u76ee\u306e\u8272\u304c\u8584\u3044\uff08\u8272\u7d20\u4f4e\u4e0b\uff09\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li>\u5f8c\u982d\u90e8\u306e\u6241\u5e73:<br>\u982d\u306e\u5f8c\u308d\u304c\u5e73\u3089\uff08\u7d76\u58c1\uff09\u306a\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/li>\n\n\n\n<li>\u4fbf\u79d8:<br>\u9811\u56fa\u306a\u4fbf\u79d8\u306b\u306a\u308a\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%8E%9F%E5%9B%A0%EF%BC%9A15%E7%95%AA%E6%9F%93%E8%89%B2%E4%BD%93%E3%81%AE%E4%B8%8D%E6%80%9D%E8%AD%B0\"><\/span><strong>\u539f\u56e0\uff1a15\u756a\u67d3\u8272\u4f53\u306e\u4e0d\u601d\u8b70<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u3054\u5bb6\u65cf\u304c\u6700\u3082\u77e5\u308a\u305f\u3044\u3053\u3068\u306e\u4e00\u3064\u304c\u300c\u539f\u56e0\u300d\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\u306f\u300115\u756a\u67d3\u8272\u4f53\uff0815q11-q13\uff09\u306b\u3042\u308b\u300cUBE3A\uff08\u30e6\u30d3\u30ad\u30c1\u30f3\u30ea\u30ac\u30fc\u30bc3A\uff09\u300d\u3068\u3044\u3046\u907a\u4f1d\u5b50\u304c\u3001\u8133\u306e\u4e2d\u3067\u3046\u307e\u304f\u50cd\u304b\u306a\u3044\u3053\u3068\u306b\u3088\u3063\u3066\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306b\u306f\u300c\u30b2\u30ce\u30e0\u5237\u308a\u8fbc\u307f\uff08\u30a4\u30f3\u30d7\u30ea\u30f3\u30c6\u30a3\u30f3\u30b0\uff09\u300d\u3068\u3044\u3046\u5c11\u3057\u8907\u96d1\u306a\u907a\u4f1d\u306e\u4ed5\u7d44\u307f\u304c\u95a2\u308f\u3063\u3066\u3044\u307e\u3059\u3002\u3067\u304d\u308b\u3060\u3051\u5206\u304b\u308a\u3084\u3059\u304f\u89e3\u8aac\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%80%8C%E6%AF%8D%E7%94%B1%E6%9D%A5%E3%80%8D%E3%81%A0%E3%81%91%E3%81%8C%E5%83%8D%E3%81%8F%E3%83%AB%E3%83%BC%E3%83%AB\"><\/span><strong>\u300c\u6bcd\u7531\u6765\u300d\u3060\u3051\u304c\u50cd\u304f\u30eb\u30fc\u30eb<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u4eba\u306f\u8ab0\u3067\u3082\u3001\u67d3\u8272\u4f53\u30922\u672c1\u7d44\uff08\u7236\u304b\u30891\u672c\u3001\u6bcd\u304b\u30891\u672c\uff09\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u901a\u5e38\u3001\u907a\u4f1d\u5b50\u306f\u7236\u7531\u6765\u3082\u6bcd\u7531\u6765\u3082\u4e21\u65b9\u50cd\u304d\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u300cUBE3A\u300d\u3068\u3044\u3046\u907a\u4f1d\u5b50\u306b\u9650\u3063\u3066\u306f\u3001\u8133\u306e\u795e\u7d4c\u7d30\u80de\u306e\u4e2d\u3067\u306f\u300c\u304a\u6bcd\u3055\u3093\u304b\u3089\u8cb0\u3063\u305f\u65b9\u3060\u3051\u304c\u50cd\u304d\u3001\u304a\u7236\u3055\u3093\u304b\u3089\u8cb0\u3063\u305f\u65b9\u306f\u7720\u3063\u3066\u3044\u308b\uff08\u50cd\u304b\u306a\u3044\uff09\u300d\u3068\u3044\u3046\u7279\u5225\u306a\u30eb\u30fc\u30eb\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3064\u307e\u308a\u3001<strong>\u300c\u304a\u6bcd\u3055\u3093\u7531\u6765\u306eUBE3A\u907a\u4f1d\u5b50\u300d\u304c\u4f55\u3089\u304b\u306e\u7406\u7531\u3067\u7121\u304f\u306a\u3063\u3066\u3057\u307e\u3063\u305f\u308a\u3001\u58ca\u308c\u3066\u3057\u307e\u3063\u305f\u308a\u3059\u308b\u3068\u3001\u4ee3\u308f\u308a\u304c\u3044\u306a\u3044\u305f\u3081\u3001\u8133\u306e\u4e2d\u3067UBE3A\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u4f5c\u3089\u308c\u306a\u304f\u306a\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/strong> \u3053\u308c\u304c\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\u306e\u539f\u56e0\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%8E%9F%E5%9B%A0%E3%81%A8%E3%81%AA%E3%82%8B4%E3%81%A4%E3%81%AE%E3%82%BF%E3%82%A4%E3%83%97\"><\/span><strong>\u539f\u56e0\u3068\u306a\u308b4\u3064\u306e\u30bf\u30a4\u30d7<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>UBE3A\u304c\u50cd\u304b\u306a\u304f\u306a\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u306f\u3001\u4e3b\u306b4\u3064\u306e\u30bf\u30a4\u30d7\u304c\u3042\u308a\u307e\u3059\u3002\u3069\u306e\u30bf\u30a4\u30d7\u304b\u306b\u3088\u3063\u3066\u3001\u75c7\u72b6\u306e\u91cd\u3055\u3084\u3001\u6b21\u306e\u304a\u5b50\u69d8\u3078\u306e\u907a\u4f1d\u306e\u78ba\u7387\uff08\u518d\u767a\u7387\uff09\u304c\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u6b20\u5931\u578b\uff08\u7d0470%\uff09\uff1a<\/strong> \u6700\u3082\u591a\u3044\u30bf\u30a4\u30d7\u3067\u3059\u3002\u6bcd\u7531\u6765\u306e15\u756a\u67d3\u8272\u4f53\u306e\u4e00\u90e8\u304c\u3054\u3063\u305d\u308a\u629c\u3051\u843d\u3061\u3066\u3044\u307e\u3059\u3002\u75c7\u72b6\u306f\u6bd4\u8f03\u7684\u91cd\u3044\u50be\u5411\u304c\u3042\u308a\u3001\u3066\u3093\u304b\u3093\u3084\u8272\u7d20\u4f4e\u4e0b\u3082\u898b\u3089\u308c\u3084\u3059\u3044\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u7247\u89aa\u6027\u30c0\u30a4\u30bd\u30df\u30fc\uff08UPD\uff09\u578b\uff08\u7d045%\uff09\uff1a<\/strong> 2\u672c\u306e15\u756a\u67d3\u8272\u4f53\u306e\u4e21\u65b9\u3092\u300c\u304a\u7236\u3055\u3093\u300d\u304b\u3089\u53d7\u3051\u7d99\u3044\u3067\u3057\u307e\u3063\u305f\u30b1\u30fc\u30b9\u3067\u3059\u3002\u6bcd\u7531\u6765\u304c\u306a\u3044\u305f\u3081\u767a\u75c7\u3057\u307e\u3059\u3002\u75c7\u72b6\u306f\u6bd4\u8f03\u7684\u8efd\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u5237\u308a\u8fbc\u307f\u5909\u7570\uff08IC\u6b20\u640d\uff09\u578b\uff08\u7d043-5%\uff09\uff1a<\/strong> \u6bcd\u7531\u6765\u306e\u67d3\u8272\u4f53\u306f\u3042\u308b\u306e\u3067\u3059\u304c\u3001\u300c\u304a\u6bcd\u3055\u3093\u7531\u6765\u3060\u3088\u300d\u3068\u3044\u3046\u76ee\u5370\uff08\u30b9\u30a4\u30c3\u30c1\uff09\u304c\u58ca\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u7236\u7531\u6765\u3068\u540c\u3058\u3088\u3046\u306b\u7720\u3063\u3066\u3057\u307e\u3063\u3066\u3044\u308b\u72b6\u614b\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>UBE3A\u5909\u7570\u578b\uff08\u7d0410%\uff09\uff1a<\/strong> \u6bcd\u7531\u6765\u306e\u907a\u4f1d\u5b50\u306f\u3042\u308b\u306e\u3067\u3059\u304c\u3001UBE3A\u907a\u4f1d\u5b50\u305d\u306e\u3082\u306e\u306b\u50b7\uff08\u5909\u7570\uff09\u304c\u5165\u3063\u3066\u3044\u3066\u6a5f\u80fd\u3057\u306a\u3044\u72b6\u614b\u3067\u3059\u3002<\/li>\n<\/ol>\n\n\n\n<p>\u203b\u6b8b\u308a\u306e\u7d0410%\u306f\u3001\u81e8\u5e8a\u7684\u306b\u306f\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\u306b\u898b\u3048\u307e\u3059\u304c\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u3067\u306f\u539f\u56e0\u304c\u7279\u5b9a\u3067\u304d\u306a\u3044\u30b1\u30fc\u30b9\u3067\u3059\uff08\u985e\u4f3c\u75be\u60a3\u306e\u53ef\u80fd\u6027\u3082\u542b\u307f\u307e\u3059\uff09\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%A8%BA%E6%96%AD%E3%81%A8%E6%A4%9C%E6%9F%BB\"><\/span><strong>\u8a3a\u65ad\u3068\u691c\u67fb<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u8a3a\u65ad\u306f\u3001\u7279\u5fb4\u7684\u306a\u75c7\u72b6\uff08\u7b11\u3044\u3001\u767a\u9054\u9045\u6ede\u3001\u5931\u8abf\u306a\u3069\uff09\u3068\u3001\u907a\u4f1d\u5b66\u7684\u691c\u67fb\u3001\u8133\u6ce2\u691c\u67fb\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u884c\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_%E8%84%B3%E6%B3%A2%E6%A4%9C%E6%9F%BB\"><\/span><strong>1. \u8133\u6ce2\u691c\u67fb<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\u306b\u7279\u5fb4\u7684\u306a\u6ce2\u5f62\uff08\u9ad8\u632f\u5e45\u5f90\u6ce2\u306a\u3069\uff09\u304c\u51fa\u308b\u305f\u3081\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u524d\u306b\u975e\u5e38\u306b\u91cd\u8981\u306a\u624b\u304c\u304b\u308a\u306b\u306a\u308a\u307e\u3059\u3002\u3066\u3093\u304b\u3093\u767a\u4f5c\u304c\u306a\u304f\u3066\u3082\u7570\u5e38\u6ce2\u5f62\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_%E9%81%BA%E4%BC%9D%E5%AD%A6%E7%9A%84%E6%A4%9C%E6%9F%BB%EF%BC%88%E7%A2%BA%E5%AE%9A%E8%A8%BA%E6%96%AD%EF%BC%89\"><\/span><strong>2. \u907a\u4f1d\u5b66\u7684\u691c\u67fb\uff08\u78ba\u5b9a\u8a3a\u65ad\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u8840\u6db2\u3092\u63a1\u53d6\u3057\u3066\u884c\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>DNA\u30e1\u30c1\u30eb\u5316\u691c\u67fb:<\/strong> \u307e\u305a\u6700\u521d\u306b\u884c\u3046\u691c\u67fb\u3067\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u7d0480%\u306e\u60a3\u8005\u3055\u3093\uff08\u6b20\u5931\u578b\u3001UPD\u578b\u3001\u5237\u308a\u8fbc\u307f\u5909\u7570\u578b\uff09\u3092\u8a3a\u65ad\u3067\u304d\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>FISH\u6cd5 \/ <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/amniocentesis-microarray\/\">\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4<\/a>\u691c\u67fb:<\/strong> \u30e1\u30c1\u30eb\u5316\u691c\u67fb\u3067\u967d\u6027\u3060\u3063\u305f\u5834\u5408\u3001\u305d\u308c\u304c\u300c\u6b20\u5931\u300d\u306b\u3088\u308b\u3082\u306e\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>UBE3A\u907a\u4f1d\u5b50\u89e3\u6790:<\/strong> \u30e1\u30c1\u30eb\u5316\u691c\u67fb\u304c\u9670\u6027\u3067\u3082\u3001\u75c7\u72b6\u304b\u3089\u5f37\u304f\u7591\u308f\u308c\u308b\u5834\u5408\u306f\u3001\u907a\u4f1d\u5b50\u306e\u914d\u5217\u3092\u7d30\u304b\u304f\u8aad\u3080\u691c\u67fb\u3092\u884c\u3044\u307e\u3059\uff08UBE3A\u5909\u7570\u578b\u3092\u898b\u3064\u3051\u308b\u305f\u3081\uff09\u3002<\/li>\n<\/ul>\n\n\n\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%B2%BB%E7%99%82%E3%81%A8%E7%AE%A1%E7%90%86\"><\/span><strong>\u6cbb\u7642\u3068\u7ba1\u7406<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u73fe\u5728\u3001\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\u3092\u6839\u672c\u7684\u306b\u6cbb\u3059\uff08\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u3092\u623b\u3059\uff09\u6cbb\u7642\u6cd5\u306f\u307e\u3060\u78ba\u7acb\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u305d\u308c\u305e\u308c\u306e\u75c7\u72b6\u306b\u5bfe\u3059\u308b\u5bfe\u75c7\u7642\u6cd5\u3068\u7642\u80b2\uff08\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\uff09\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u751f\u6d3b\u306e\u8cea\u3092\u5927\u304d\u304f\u5411\u4e0a\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_%E3%81%A6%E3%82%93%E3%81%8B%E3%82%93%E3%81%AE%E7%AE%A1%E7%90%86\"><\/span><strong>1. \u3066\u3093\u304b\u3093\u306e\u7ba1\u7406<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u3066\u3093\u304b\u3093\u767a\u4f5c\u306f\u3001\u653e\u7f6e\u3059\u308b\u3068\u8133\u306e\u767a\u9054\u306b\u60aa\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u305f\u3081\u3001\u6297\u3066\u3093\u304b\u3093\u85ac\u3067\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u6709\u52b9\u306a\u85ac:<\/strong> \u30d0\u30eb\u30d7\u30ed\u9178\u3001\u30af\u30ed\u30ca\u30bc\u30d1\u30e0\u3001\u30ec\u30d9\u30c1\u30e9\u30bb\u30bf\u30e0\u306a\u3069\u304c\u3088\u304f\u4f7f\u308f\u308c\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u6ce8\u610f\u3059\u3079\u304d\u85ac:<\/strong> \u30ab\u30eb\u30d0\u30de\u30bc\u30d4\u30f3\u3084\u30d3\u30ac\u30d0\u30c8\u30ea\u30f3\u306a\u3069\u306f\u3001\u304b\u3048\u3063\u3066\u767a\u4f5c\u3092\u60aa\u5316\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u907f\u3051\u308b\u3079\u304d\u3068\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u5c02\u9580\u533b\u306e\u5224\u65ad\u306b\u3088\u308a\u307e\u3059\uff09\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_%E7%9D%A1%E7%9C%A0%E9%9A%9C%E5%AE%B3%E3%81%AE%E5%AF%BE%E5%BF%9C\"><\/span><strong>2. \u7761\u7720\u969c\u5bb3\u306e\u5bfe\u5fdc<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u3054\u5bb6\u65cf\u306e\u8ca0\u62c5\u3092\u6e1b\u3089\u3059\u305f\u3081\u306b\u3082\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u74b0\u5883\u8abf\u6574:<\/strong> \u5bdd\u308b\u524d\u306e\u30eb\u30fc\u30c6\u30a3\u30f3\u3092\u4f5c\u308b\u3001\u90e8\u5c4b\u3092\u6697\u304f\u3059\u308b\u3001\u5b89\u5168\u306a\u30d9\u30c3\u30c9\u3092\u7528\u610f\u3059\u308b\u3002<\/li>\n\n\n\n<li><strong>\u85ac\u7269\u7642\u6cd5:<\/strong> \u751f\u6d3b\u30ea\u30ba\u30e0\u3092\u6574\u3048\u308b\u305f\u3081\u306b\u3001\u30e1\u30e9\u30c8\u30cb\u30f3\u3084\u7761\u7720\u5c0e\u5165\u5264\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_%E9%81%8B%E5%8B%95%E3%83%BB%E8%BA%AB%E4%BD%93%E9%9D%A2%E3%81%AE%E3%82%B1%E3%82%A2\"><\/span><strong>3. \u904b\u52d5\u30fb\u8eab\u4f53\u9762\u306e\u30b1\u30a2<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u7406\u5b66\u7642\u6cd5 (PT):<\/strong> \u30d0\u30e9\u30f3\u30b9\u611f\u899a\u3092\u990a\u3044\u3001\u6b69\u884c\u306e\u5b89\u5b9a\u3092\u76ee\u6307\u3057\u307e\u3059\u3002\u5074\u5f2f\uff08\u80cc\u9aa8\u306e\u66f2\u304c\u308a\uff09\u306e\u30c1\u30a7\u30c3\u30af\u3082\u5b9a\u671f\u7684\u306b\u884c\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u88c5\u5177\u7642\u6cd5:<\/strong> \u8db3\u9996\u304c\u4e0d\u5b89\u5b9a\u306a\u5834\u5408\u306f\u3001\u30a4\u30f3\u30bd\u30fc\u30eb\u3084\u77ed\u4e0b\u80a2\u88c5\u5177\uff08\u9774\u578b\u88c5\u5177\uff09\u3092\u4f5c\u6210\u3057\u3066\u6b69\u884c\u3092\u52a9\u3051\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"4_%E3%82%B3%E3%83%9F%E3%83%A5%E3%83%8B%E3%82%B1%E3%83%BC%E3%82%B7%E3%83%A7%E3%83%B3%E6%94%AF%E6%8F%B4%EF%BC%88%E8%A8%80%E8%AA%9E%E8%81%B4%E8%A6%9A%E7%99%82%E6%B3%95%EF%BC%9AST%EF%BC%89\"><\/span><strong>4. \u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u652f\u63f4\uff08\u8a00\u8a9e\u8074\u899a\u7642\u6cd5\uff1aST\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u8a00\u8449\u304c\u51fa\u306a\u304f\u3066\u3082\u3001\u5f7c\u3089\u306f\u300c\u4f1d\u3048\u305f\u3044\u300d\u6c17\u6301\u3061\u3092\u305f\u304f\u3055\u3093\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>AAC\uff08\u62e1\u5927\u4ee3\u66ff\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\uff09:<\/strong> \u7d75\u30ab\u30fc\u30c9\u3001\u30b5\u30a4\u30f3\uff08\u30b8\u30a7\u30b9\u30c1\u30e3\u30fc\uff09\u3001\u30bf\u30d6\u30ec\u30c3\u30c8\u7aef\u672b\uff08VOCA\uff09\u306a\u3069\u3092\u6d3b\u7528\u3057\u3066\u3001\u610f\u601d\u4f1d\u9054\u306e\u624b\u6bb5\u3092\u78ba\u4fdd\u3057\u307e\u3059\u3002\u7406\u89e3\u529b\u306f\u9ad8\u3044\u305f\u3081\u3001\u3053\u3046\u3057\u305f\u30c4\u30fc\u30eb\u3092\u4f7f\u3044\u3053\u306a\u305b\u308b\u304a\u5b50\u69d8\u306f\u591a\u3044\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"5_%E9%A3%9F%E4%BA%8B%E3%83%BB%E6%B6%88%E5%8C%96%E5%99%A8%E3%81%AE%E3%82%B1%E3%82%A2\"><\/span><strong>5. \u98df\u4e8b\u30fb\u6d88\u5316\u5668\u306e\u30b1\u30a2<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u4fbf\u79d8\u306b\u5bfe\u3057\u3066\u306f\u3001\u6c34\u5206\u6442\u53d6\u3084\u85ac\u306b\u3088\u308b\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3092\u7a4d\u6975\u7684\u306b\u884c\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li>\u904e\u98df\u3084\u7570\u98df\uff08\u98df\u3079\u7269\u3067\u306a\u3044\u3082\u306e\u3092\u53e3\u306b\u5165\u308c\u308b\uff09\u304c\u898b\u3089\u308c\u308b\u5834\u5408\u306f\u3001\u74b0\u5883\u8abf\u6574\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%87%A8%E5%BA%8A%E8%A9%A6%E9%A8%93%E3%81%A8%E7%A0%94%E7%A9%B6%E3%81%AE%E6%9C%80%E5%89%8D%E7%B7%9A%EF%BC%88%E5%B8%8C%E6%9C%9B%E3%81%AE%E5%85%89%EF%BC%89\"><\/span><strong>\u81e8\u5e8a\u8a66\u9a13\u3068\u7814\u7a76\u306e\u6700\u524d\u7dda\uff08\u5e0c\u671b\u306e\u5149\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u300c\u6cbb\u7642\u6cd5\u304c\u306a\u3044\u300d\u3068\u304a\u4f1d\u3048\u3057\u307e\u3057\u305f\u304c\u3001\u5b9f\u306f\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4\u306f\u3001\u73fe\u5728<strong>\u4e16\u754c\u4e2d\u3067\u6700\u3082\u6d3b\u767a\u306b\u6cbb\u7642\u85ac\u306e\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u308b\u795e\u7d4c\u75be\u60a3\u306e\u4e00\u3064<\/strong>\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u306a\u305c\u306a\u3089\u3001\u300c\u7236\u7531\u6765\u306e\u7720\u3063\u3066\u3044\u308bUBE3A\u907a\u4f1d\u5b50\u300d\u3092\u85ac\u3067\u300c\u76ee\u899a\u3081\u3055\u305b\u308b\u300d\u3053\u3068\u304c\u3067\u304d\u308c\u3070\u3001\u7406\u8ad6\u4e0a\u306f\u75c7\u72b6\u3092\u6539\u5584\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u73fe\u5728\u3001\u30a2\u30f3\u30c1\u30bb\u30f3\u30b9\u30aa\u30ea\u30b4\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\uff08ASO\uff09\u7642\u6cd5\u306a\u3069\u3001\u3044\u304f\u3064\u304b\u306e\u6709\u671b\u306a\u6cbb\u7642\u6cd5\u306e\u81e8\u5e8a\u8a66\u9a13\uff08\u6cbb\u9a13\uff09\u304c\u6d77\u5916\u3084\u65e5\u672c\u3067\u9032\u884c\u4e2d\u3067\u3059\u3002\u6570\u5e74\u301c\u5341\u6570\u5e74\u5f8c\u306b\u306f\u3001\u75c7\u72b6\u3092\u5287\u7684\u306b\u6539\u5584\u3059\u308b\u6cbb\u7642\u85ac\u304c\u767b\u5834\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u5927\u304d\u306a\u5e0c\u671b\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"426\" src=\"\/nipt\/wp-content\/uploads\/2025\/09\/24237675_s.webp\" alt=\"\u533b\u8005\" class=\"wp-image-116879\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%97%A5%E3%80%85%E3%81%AE%E7%94%9F%E6%B4%BB%E3%81%A7%E3%81%AE%E6%B3%A8%E6%84%8F%E7%82%B9\"><\/span><strong>\u65e5\u3005\u306e\u751f\u6d3b\u3067\u306e\u6ce8\u610f\u70b9<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u6c34\u3078\u306e\u4e8b\u6545\u9632\u6b62:<br>\u6c34\u3078\u306e\u57f7\u7740\u304c\u5f37\u3044\u305f\u3081\u3001\u304a\u98a8\u5442\u5834\u3084\u6d17\u6fef\u6a5f\u3001\u30c8\u30a4\u30ec\u3001\u5c4b\u5916\u306e\u6c34\u8def\u3084\u6c60\u306a\u3069\u3067\u306e\u4e8b\u6545\u306b\u5341\u5206\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u9375\u3092\u304b\u3051\u308b\u306a\u3069\u306e\u7269\u7406\u7684\u306a\u5bfe\u7b56\u304c\u5fc5\u9808\u3067\u3059\u3002<\/li>\n\n\n\n<li>\u71b1\u4e2d\u75c7\u5bfe\u7b56:<br>\u4f53\u6e29\u8abf\u7bc0\u304c\u82e6\u624b\u3067\u3001\u71b1\u304c\u3053\u3082\u308a\u3084\u3059\u3044\u304a\u5b50\u69d8\u304c\u591a\u3044\u3067\u3059\u3002\u590f\u5834\u306f\u3053\u307e\u3081\u306a\u6c34\u5206\u88dc\u7d66\u3068\u5ba4\u6e29\u7ba1\u7406\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n\n\n\n<li>\u884c\u52d5\u9762:<br>\u5b09\u3057\u3044\u6642\u306b\u8208\u596e\u3057\u3066\u3001\u9aea\u3092\u5f15\u3063\u5f35\u3063\u305f\u308a\u3001\u53e9\u3044\u305f\u308a\u3057\u3066\u3057\u307e\u3046\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u653b\u6483\u6027\u3067\u306f\u306a\u304f\u3001\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u306e\u4e00\u7a2e\u3067\u3042\u308b\u3053\u3068\u3082\u591a\u3044\u3067\u3059\u3002\u300c\u30c0\u30e1\u300d\u3068\u53f1\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u5225\u306e\u8868\u73fe\u65b9\u6cd5\uff08\u624b\u3092\u63e1\u308b\u306a\u3069\uff09\u3092\u6559\u3048\u3066\u3042\u3052\u308b\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%81%BE%E3%81%A8%E3%82%81\"><\/span><strong>\u307e\u3068\u3081<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u3053\u3053\u307e\u3067\u306e\u91cd\u8981\u30dd\u30a4\u30f3\u30c8\u3092\u632f\u308a\u8fd4\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u30a2\u30f3\u30b8\u30a7\u30eb\u30de\u30f3\u75c7\u5019\u7fa4<\/strong>\u306f\u300115\u756a\u67d3\u8272\u4f53\u306eUBE3A\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u4e0d\u5168\u306b\u3088\u308b\u75be\u60a3\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u4e3b\u306a\u75c7\u72b6<\/strong>\u306f\u3001\u7b11\u9854\u3001\u91cd\u5ea6\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u3001\u8a00\u8449\u306e\u9045\u308c\u3001\u5931\u8abf\u3001\u3066\u3093\u304b\u3093\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u539f\u56e0<\/strong>\u306b\u306f4\u3064\u306e\u30bf\u30a4\u30d7\uff08\u6b20\u5931\u3001UPD\u3001\u5237\u308a\u8fbc\u307f\u5909\u7570\u3001UBE3A\u5909\u7570\uff09\u304c\u3042\u308a\u3001\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u78ba\u8a8d\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u5bff\u547d<\/strong>\u306f\u6b63\u5e38\u3067\u3001\u5927\u4eba\u306b\u306a\u3063\u3066\u3082\u7b11\u9854\u306e\u7d76\u3048\u306a\u3044\u611b\u3059\u3079\u304d\u5b58\u5728\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u6cbb\u7642<\/strong>\u306f\u3001\u3066\u3093\u304b\u3093\u7ba1\u7406\u3068\u7642\u80b2\u304c\u4e2d\u5fc3\u3067\u3059\u304c\u3001\u5c06\u6765\u7684\u306a\u6839\u672c\u6cbb\u7642\u306e\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%AE%B6%E6%97%8F%E3%81%B8%E3%81%AE%E3%83%A1%E3%83%83%E3%82%BB%E3%83%BC%E3%82%B8\"><\/span><strong>\u5bb6\u65cf\u3078\u306e\u30e1\u30c3\u30bb\u30fc\u30b8<\/strong><span 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