{"id":122560,"date":"2026-01-14T11:03:24","date_gmt":"2026-01-14T02:03:24","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?p=122560"},"modified":"2026-03-27T16:28:30","modified_gmt":"2026-03-27T07:28:30","slug":"bbsoas-optic-atrophy-syndrome-guide","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/","title":{"rendered":"Bosch-Boonstra-Schaaf Optic Atrophy Syndrome"},"content":{"rendered":"\n<p>\u8fd1\u5e74\u3001\u30b2\u30ce\u30e0\u89e3\u6790\u6280\u8853\u306e\u98db\u8e8d\u7684\u306a\u9032\u6b69\u306b\u3088\u308a\u3001\u3053\u308c\u307e\u3067\u300c\u539f\u56e0\u4e0d\u660e\u300d\u3068\u3055\u308c\u3066\u304d\u305f\u591a\u304f\u306e\u5e0c\u5c11\u75be\u60a3\u306e\u6b63\u4f53\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u4e2d\u306e\u4e00\u3064\u304c\u3001Bosch-Boonstra-Schaaf Optic Atrophy Syndrome\uff08\u30dc\u30c3\u30b7\u30e5\u30fb\u30dc\u30fc\u30f3\u30b9\u30c8\u30e9\u30fb\u30b7\u30e3\u30fc\u30d5\u8996\u795e\u7d4c\u840e\u7e2e\u75c7\u5019\u7fa4\u3001\u4ee5\u4e0bBBSOAS\uff09\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u75be\u60a3\u306f\u3001\u8996\u795e\u7d4c\u840e\u7e2e\u3092\u4e2d\u6838\u75c7\u72b6\u3068\u3057\u306a\u304c\u3089\u3082\u3001\u5168\u8eab\u306e\u795e\u7d4c\u767a\u9054\u306b\u591a\u5927\u306a\u5f71\u97ff\u3092\u53ca\u307c\u3059\u8907\u96d1\u306a\u907a\u4f1d\u6027\u75be\u60a3\u3067\u3059\u3002\u8a3a\u65ad\u304c\u4e0b\u3055\u308c\u305f\u3070\u304b\u308a\u306e\u3054\u5bb6\u65cf\u3084\u3001\u3053\u306e\u96e3\u89e3\u306a\u75be\u60a3\u306e\u7406\u89e3\u3092\u6df1\u3081\u3088\u3046\u3068\u3059\u308b\u533b\u7642\u5f93\u4e8b\u8005\u306e\u65b9\u3005\u306b\u3068\u3063\u3066\u3001\u6b63\u78ba\u306a\u60c5\u5831\u306e\u96c6\u7d04\u306f\u6700\u512a\u5148\u4e8b\u9805\u3068\u8a00\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p>\u672c\u8a18\u4e8b\u3067\u306f\u3001BBSOAS\u306e\u75c5\u7406\u5b66\u7684\u80cc\u666f\u3001\u81e8\u5e8a\u7684\u7279\u5fb4\u3001\u305d\u3057\u3066\u73fe\u5728\u9032\u3081\u3089\u308c\u3066\u3044\u308b\u7814\u7a76\u306e\u6700\u524d\u7dda\u306b\u3064\u3044\u3066\u3001\u5c02\u9580\u7684\u306a\u8996\u70b9\u304b\u3089\u8a73\u7d30\u306b\u6398\u308a\u4e0b\u3052\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n<!--nipt_mono-->\r\n<div class=\"nipt-mono\">\r\n    <div class=\"nipt-mono-btn\">\r\n        <a href=\"\/nipt\/nipt-mono\/\">\r\n            <img decoding=\"async\" loading=\"lazy\" src=\"\/nipt\/wp-content\/uploads\/2026\/03\/NIPT-MONO.webp\" alt=\"NIPT-MONO\u3067\u8abf\u3079\u3089\u308c\u307e\u3059\">\r\n         <\/a>\r\n    <\/div>\r\n<\/div>\r\n\r\n<style>\r\n.nipt-mono {\r\n    text-align: center; \/* \u89aa\u8981\u7d20\u3067\u6a2a\u4e2d\u592e *\/\r\n}\r\n.nipt-mono a img {\r\n    display: inline-block; \/* \u753b\u50cf\u3092\u30a4\u30f3\u30e9\u30a4\u30f3\u30d6\u30ed\u30c3\u30af\u5316\u3057\u3066 text-align \u306b\u53cd\u6620 *\/\r\n    width: 333px;\r\n}\r\n<\/style>\r\n<!--\/nipt_mono-->\r\n\r\n\n\n\n\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#1_BBSOAS%E3%81%AE%E5%AE%9A%E7%BE%A9%E3%81%A8%E9%81%BA%E4%BC%9D%E5%AD%A6%E7%9A%84%E8%83%8C%E6%99%AF%EF%BC%9ANR2F1%E9%81%BA%E4%BC%9D%E5%AD%90%E3%81%AE%E5%BD%B9%E5%89%B2\" >1. BBSOAS\u306e\u5b9a\u7fa9\u3068\u907a\u4f1d\u5b66\u7684\u80cc\u666f\uff1aNR2F1\u907a\u4f1d\u5b50\u306e\u5f79\u5272<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#NR2F1%E9%81%BA%E4%BC%9D%E5%AD%90%E3%81%AE%E6%A9%9F%E8%83%BD\" >NR2F1\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E5%A4%89%E7%95%B0%E3%81%AE%E7%A8%AE%E9%A1%9E%E3%81%A8%E7%99%BA%E7%97%87%E6%A9%9F%E5%BA%8F\" >\u5909\u7570\u306e\u7a2e\u985e\u3068\u767a\u75c7\u6a5f\u5e8f<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#2_%E8%87%A8%E5%BA%8A%E7%9A%84%E7%89%B9%E5%BE%B4%EF%BC%9A%E5%A4%9A%E9%9D%A2%E7%9A%84%E3%81%AA%E7%97%87%E7%8A%B6%E3%81%AE%E7%8F%BE%E3%82%8C%E6%96%B9\" >2. \u81e8\u5e8a\u7684\u7279\u5fb4\uff1a\u591a\u9762\u7684\u306a\u75c7\u72b6\u306e\u73fe\u308c\u65b9<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E8%A6%96%E8%A6%9A%E9%9A%9C%E5%AE%B3%EF%BC%88%E8%A6%96%E7%A5%9E%E7%B5%8C%E8%90%8E%E7%B8%AE%E3%81%A8%E7%9A%AE%E8%B3%AA%E8%A6%96%E8%A6%9A%E9%9A%9C%E5%AE%B3%EF%BC%89\" >\u8996\u899a\u969c\u5bb3\uff08\u8996\u795e\u7d4c\u840e\u7e2e\u3068\u76ae\u8cea\u8996\u899a\u969c\u5bb3\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E7%A5%9E%E7%B5%8C%E7%99%BA%E9%81%94%E3%81%AE%E9%81%85%E5%BB%B6%E3%81%A8%E7%9F%A5%E7%9A%84%E9%9A%9C%E5%AE%B3\" >\u795e\u7d4c\u767a\u9054\u306e\u9045\u5ef6\u3068\u77e5\u7684\u969c\u5bb3<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E9%9A%8F%E4%BC%B4%E3%81%99%E3%82%8B%E7%A5%9E%E7%B5%8C%E5%AD%A6%E7%9A%84%E3%83%BB%E8%BA%AB%E4%BD%93%E7%9A%84%E7%89%B9%E5%BE%B4\" >\u968f\u4f34\u3059\u308b\u795e\u7d4c\u5b66\u7684\u30fb\u8eab\u4f53\u7684\u7279\u5fb4<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#3_%E8%A8%BA%E6%96%AD%E3%83%97%E3%83%AD%E3%82%BB%E3%82%B9%E3%81%A8%E6%9C%80%E6%96%B0%E3%81%AE%E6%A4%9C%E6%9F%BB%E6%89%8B%E6%B3%95\" >3. \u8a3a\u65ad\u30d7\u30ed\u30bb\u30b9\u3068\u6700\u65b0\u306e\u691c\u67fb\u624b\u6cd5<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E9%81%BA%E4%BC%9D%E5%AD%90%E6%A4%9C%E6%9F%BB%EF%BC%88%E7%A2%BA%E5%AE%9A%E8%A8%BA%E6%96%AD%E3%81%AE%E3%82%B4%E3%83%BC%E3%83%AB%E3%83%89%E3%82%B9%E3%82%BF%E3%83%B3%E3%83%80%E3%83%BC%E3%83%89%EF%BC%89\" >\u907a\u4f1d\u5b50\u691c\u67fb\uff08\u78ba\u5b9a\u8a3a\u65ad\u306e\u30b4\u30fc\u30eb\u30c9\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E8%87%A8%E5%BA%8A%E7%9A%84%E8%A9%95%E4%BE%A1\" >\u81e8\u5e8a\u7684\u8a55\u4fa1<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#4_%E6%B2%BB%E7%99%82%E3%81%A8%E3%83%9E%E3%83%8D%E3%82%B8%E3%83%A1%E3%83%B3%E3%83%88%EF%BC%9A%E3%83%81%E3%83%BC%E3%83%A0%E5%8C%BB%E7%99%82%E3%81%AE%E9%87%8D%E8%A6%81%E6%80%A7\" >4. \u6cbb\u7642\u3068\u30de\u30cd\u30b8\u30e1\u30f3\u30c8\uff1a\u30c1\u30fc\u30e0\u533b\u7642\u306e\u91cd\u8981\u6027<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E5%A4%9A%E8%81%B7%E7%A8%AE%E9%80%A3%E6%90%BA%E3%81%AB%E3%82%88%E3%82%8B%E5%8C%85%E6%8B%AC%E7%9A%84%E3%82%B1%E3%82%A2\" >\u591a\u8077\u7a2e\u9023\u643a\u306b\u3088\u308b\u5305\u62ec\u7684\u30b1\u30a2<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E6%97%A9%E6%9C%9F%E4%BB%8B%E5%85%A5%E3%81%AE%E6%84%8F%E7%BE%A9\" >\u65e9\u671f\u4ecb\u5165\u306e\u610f\u7fa9<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#5_%E6%9C%AA%E6%9D%A5%E3%81%B8%E3%81%AE%E5%B1%95%E6%9C%9B%EF%BC%9A%E7%A0%94%E7%A9%B6%E3%81%AE%E6%9C%80%E5%89%8D%E7%B7%9A\" >5. \u672a\u6765\u3078\u306e\u5c55\u671b\uff1a\u7814\u7a76\u306e\u6700\u524d\u7dda<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E7%96%BE%E6%82%A3%E3%83%A2%E3%83%87%E3%83%AB%E3%81%AE%E7%A0%94%E7%A9%B6\" >\u75be\u60a3\u30e2\u30c7\u30eb\u306e\u7814\u7a76<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E5%89%B5%E8%96%AC%E3%81%A8%E9%81%BA%E4%BC%9D%E5%AD%90%E6%B2%BB%E7%99%82%E3%81%AE%E5%8F%AF%E8%83%BD%E6%80%A7\" >\u5275\u85ac\u3068\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u53ef\u80fd\u6027<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E6%82%A3%E8%80%85%E3%83%AC%E3%82%B8%E3%82%B9%E3%83%88%E3%83%AA%E3%81%A8%E3%82%B3%E3%83%9F%E3%83%A5%E3%83%8B%E3%83%86%E3%82%A3\" >\u60a3\u8005\u30ec\u30b8\u30b9\u30c8\u30ea\u3068\u30b3\u30df\u30e5\u30cb\u30c6\u30a3<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bbsoas-optic-atrophy-syndrome-guide\/#%E7%B5%90%E8%AB%96%EF%BC%9A%E7%90%86%E8%A7%A3%E3%81%A8%E5%85%B1%E7%94%9F%E3%81%AE%E3%81%9F%E3%82%81%E3%81%AB\" >\u7d50\u8ad6\uff1a\u7406\u89e3\u3068\u5171\u751f\u306e\u305f\u3081\u306b<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_BBSOAS%E3%81%AE%E5%AE%9A%E7%BE%A9%E3%81%A8%E9%81%BA%E4%BC%9D%E5%AD%A6%E7%9A%84%E8%83%8C%E6%99%AF%EF%BC%9ANR2F1%E9%81%BA%E4%BC%9D%E5%AD%90%E3%81%AE%E5%BD%B9%E5%89%B2\"><\/span><strong>1. BBSOAS\u306e\u5b9a\u7fa9\u3068\u907a\u4f1d\u5b66\u7684\u80cc\u666f\uff1aNR2F1\u907a\u4f1d\u5b50\u306e\u5f79\u5272<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>BBSOAS\u306f\u3001\u7b2c5\u67d3\u8272\u4f53\u306b\u4f4d\u7f6e\u3059\u308b<strong>NR2F1\u907a\u4f1d\u5b50<\/strong>\uff08COUP-TF1\u3068\u3057\u3066\u3082\u77e5\u3089\u308c\u308b\uff09\u306e\u30d8\u30c6\u30ed\u63a5\u5408\u578b\u5909\u7570\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u3001\u5e38\u67d3\u8272\u4f53\u512a\u6027\u907a\u4f1d\u75be\u60a3\u3067\u3059\u30022014\u5e74\u306bBosch\u3001Boonstra\u3001Schaaf\u3089\u306b\u3088\u3063\u3066\u521d\u3081\u3066\u5831\u544a\u3055\u308c\u305f\u6bd4\u8f03\u7684\u65b0\u3057\u3044\u75be\u60a3\u6982\u5ff5\u3067\u3042\u308a\u3001\u305d\u306e\u5e0c\u5c11\u6027\u304b\u3089\u6b63\u78ba\u306a\u6709\u75c5\u7387\u306f\u307e\u3060\u78ba\u5b9a\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"NR2F1%E9%81%BA%E4%BC%9D%E5%AD%90%E3%81%AE%E6%A9%9F%E8%83%BD\"><\/span><strong>NR2F1\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>NR2F1\u306f\u3001\u8ee2\u5199\u56e0\u5b50\u3068\u3057\u3066\u50cd\u304f\u6838\u5185\u53d7\u5bb9\u4f53\u30d5\u30a1\u30df\u30ea\u30fc\u306e\u4e00\u54e1\u3067\u3059\u3002\u80ce\u5150\u671f\u306e\u8133\u306e\u767a\u80b2\u306b\u304a\u3044\u3066\u6975\u3081\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u304a\u308a\u3001\u7279\u306b\u4ee5\u4e0b\u306e\u30d7\u30ed\u30bb\u30b9\u306e\u5236\u5fa1\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8996\u795e\u7d4c\u306e\u8ef8\u7d22\u8a98\u5c0e\uff1a<\/strong> \u7db2\u819c\u304b\u3089\u8133\u3078\u3068\u8996\u899a\u60c5\u5831\u3092\u4f1d\u3048\u308b\u8996\u795e\u7d4c\u304c\u3001\u6b63\u3057\u304f\u914d\u7dda\u3055\u308c\u308b\u305f\u3081\u306e\u30ac\u30a4\u30c9\u5f79\u3092\u52d9\u3081\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u5927\u8133\u76ae\u8cea\u306e\u30d1\u30bf\u30fc\u30cb\u30f3\u30b0\uff1a<\/strong> \u8133\u306e\u5404\u9818\u57df\u304c\u7279\u5b9a\u306e\u6a5f\u80fd\uff08\u8996\u899a\u3001\u8074\u899a\u3001\u904b\u52d5\u306a\u3069\uff09\u3092\u6301\u3064\u3088\u3046\u306b\u5206\u5316\u3059\u308b\u904e\u7a0b\u3092\u5236\u5fa1\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u795e\u7d4c\u7d30\u80de\u306e\u5897\u6b96\u3068\u5206\u5316\uff1a<\/strong> \u9069\u5207\u306a\u6570\u306e\u795e\u7d4c\u7d30\u80de\u304c\u751f\u6210\u3055\u308c\u3001\u6b63\u3057\u3044\u5834\u6240\u306b\u914d\u7f6e\u3055\u308c\u308b\u3088\u3046\u8abf\u6574\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%A4%89%E7%95%B0%E3%81%AE%E7%A8%AE%E9%A1%9E%E3%81%A8%E7%99%BA%E7%97%87%E6%A9%9F%E5%BA%8F\"><\/span><strong>\u5909\u7570\u306e\u7a2e\u985e\u3068\u767a\u75c7\u6a5f\u5e8f<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>BBSOAS\u3092\u5f15\u304d\u8d77\u3053\u3059NR2F1\u306e\u5909\u7570\u306b\u306f\u3001\u70b9\u5909\u7570\uff08\u30df\u30b9\u30bb\u30f3\u30b9\u5909\u7570\u3001\u30ca\u30f3\u30bb\u30f3\u30b9\u5909\u7570\uff09\u3084\u3001\u67d3\u8272\u4f53\u306e\u4e00\u90e8\u306e\u6b20\u5931\u304c\u542b\u307e\u308c\u307e\u3059\u3002\u591a\u304f\u306e\u5834\u5408\u3001\u3053\u308c\u3089\u306e\u5909\u7570\u306f<strong>de novo\uff08\u7a81\u7136\u5909\u7570\uff09<\/strong>\u3001\u3064\u307e\u308a\u4e21\u89aa\u304b\u3089\u306e\u907a\u4f1d\u3067\u306f\u306a\u304f\u53d7\u7cbe\u5375\u306e\u6bb5\u968e\u3067\u767a\u751f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u75c5\u614b\u306e\u672c\u8cea\u306f\u300c\u30cf\u30d7\u30ed\u4e0d\u5168\uff08Haploinsufficiency\uff09\u300d\u306b\u3042\u308a\u307e\u3059\u3002\u6b63\u5e38\u306a\u907a\u4f1d\u5b50\u304c1\u3064\u3060\u3051\u3067\u306f\u3001\u795e\u7d4c\u767a\u9054\u306b\u5fc5\u8981\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u91cf\u3092\u5341\u5206\u306b\u78ba\u4fdd\u3067\u304d\u306a\u3044\u305f\u3081\u3001\u8996\u899a\u7cfb\u3084\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306b\u5e83\u7bc4\u306a\u969c\u5bb3\u304c\u751f\u3058\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_%E8%87%A8%E5%BA%8A%E7%9A%84%E7%89%B9%E5%BE%B4%EF%BC%9A%E5%A4%9A%E9%9D%A2%E7%9A%84%E3%81%AA%E7%97%87%E7%8A%B6%E3%81%AE%E7%8F%BE%E3%82%8C%E6%96%B9\"><\/span><strong>2. \u81e8\u5e8a\u7684\u7279\u5fb4\uff1a\u591a\u9762\u7684\u306a\u75c7\u72b6\u306e\u73fe\u308c\u65b9<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>BBSOAS\u306e\u81e8\u5e8a\u50cf\u306f\u975e\u5e38\u306b\u591a\u69d8\u3067\u3042\u308a\u3001\u540c\u3058\u907a\u4f1d\u5b50\u5909\u7570\u3092\u6301\u3064\u500b\u4f53\u9593\u3067\u3082\u75c7\u72b6\u306e\u91cd\u75c7\u5ea6\u306f\u7570\u306a\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u5171\u901a\u3057\u3066\u898b\u3089\u308c\u308b\u4e3b\u8981\u306a\u75c7\u72b6\u304c\u3044\u304f\u3064\u304b\u5b58\u5728\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%A6%96%E8%A6%9A%E9%9A%9C%E5%AE%B3%EF%BC%88%E8%A6%96%E7%A5%9E%E7%B5%8C%E8%90%8E%E7%B8%AE%E3%81%A8%E7%9A%AE%E8%B3%AA%E8%A6%96%E8%A6%9A%E9%9A%9C%E5%AE%B3%EF%BC%89\"><\/span><strong>\u8996\u899a\u969c\u5bb3\uff08\u8996\u795e\u7d4c\u840e\u7e2e\u3068\u76ae\u8cea\u8996\u899a\u969c\u5bb3\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u75be\u60a3\u540d\u306b\u3082\u3042\u308b\u901a\u308a\u3001\u8996\u795e\u7d4c\u840e\u7e2e\uff08Optic Atrophy\uff09\u304c\u6700\u3082\u7279\u5fb4\u7684\u306a\u6240\u898b\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u8996\u795e\u7d4c\u4e73\u982d\u306e\u84bc\u767d\uff1a<\/strong> \u773c\u5e95\u691c\u67fb\u306b\u304a\u3044\u3066\u3001\u8996\u795e\u7d4c\u306e\u5909\u6027\u3092\u793a\u3059\u9752\u767d\u3044\u5916\u89b3\u304c\u89b3\u5bdf\u3055\u308c\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u8996\u529b\u4f4e\u4e0b\uff1a<\/strong> \u8efd\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u8996\u899a\u969c\u5bb3\u307e\u3067\u5e45\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>CVI\uff08\u76ae\u8cea\u8996\u899a\u969c\u5bb3\uff09\uff1a<\/strong> \u76ee\u305d\u306e\u3082\u306e\u306e\u554f\u984c\u3060\u3051\u3067\u306a\u304f\u3001\u8133\u306e\u8996\u899a\u51e6\u7406\u80fd\u529b\u306e\u6b20\u5982\u306b\u3088\u308a\u3001\u7269\u304c\u898b\u3048\u306b\u304f\u3044\u3001\u3042\u308b\u3044\u306f\u8a8d\u8b58\u3057\u306b\u304f\u3044\u72b6\u614b\u304c\u751f\u3058\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%A5%9E%E7%B5%8C%E7%99%BA%E9%81%94%E3%81%AE%E9%81%85%E5%BB%B6%E3%81%A8%E7%9F%A5%E7%9A%84%E9%9A%9C%E5%AE%B3\"><\/span><strong>\u795e\u7d4c\u767a\u9054\u306e\u9045\u5ef6\u3068\u77e5\u7684\u969c\u5bb3<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u307b\u307c\u3059\u3079\u3066\u306e\u75c7\u4f8b\u3067\u3001\u767a\u9054\u306e\u9045\u308c\u304c\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u904b\u52d5\u767a\u9054\u9045\u6ede\uff1a<\/strong> \u9996\u306e\u5ea7\u308a\u3001\u304a\u5ea7\u308a\u3001\u6b69\u884c\u306a\u3069\u306e\u904b\u52d5\u6307\u6a19\u306e\u9054\u6210\u304c\u9045\u308c\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u7b4b\u7dca\u5f35\u4f4e\u4e0b\uff08\u4f4e\u7dca\u5f35\uff09\u3092\u4f34\u3046\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u8a00\u8a9e\u767a\u9054\u9045\u6ede\uff1a<\/strong> \u767a\u8a9e\u306e\u9045\u308c\u3084\u3001\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u80fd\u529b\u306e\u7372\u5f97\u306b\u56f0\u96e3\u3092\u4f34\u3044\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\uff1a<\/strong> \u8efd\u5ea6\u304b\u3089\u91cd\u5ea6\u307e\u3067\u591a\u5c90\u306b\u308f\u305f\u308a\u307e\u3059\u304c\u3001\u591a\u304f\u306f\u5b66\u7fd2\u652f\u63f4\u3092\u5fc5\u8981\u3068\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E9%9A%8F%E4%BC%B4%E3%81%99%E3%82%8B%E7%A5%9E%E7%B5%8C%E5%AD%A6%E7%9A%84%E3%83%BB%E8%BA%AB%E4%BD%93%E7%9A%84%E7%89%B9%E5%BE%B4\"><\/span><strong>\u968f\u4f34\u3059\u308b\u795e\u7d4c\u5b66\u7684\u30fb\u8eab\u4f53\u7684\u7279\u5fb4<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u3066\u3093\u304b\u3093\uff1a<\/strong> \u591a\u304f\u306e\u60a3\u8005\u304c\u75d9\u6523\u767a\u4f5c\u3092\u7d4c\u9a13\u3057\u307e\u3059\u3002\u96e3\u6cbb\u6027\u3068\u306a\u308b\u30b1\u30fc\u30b9\u3082\u3042\u308a\u3001\u65e9\u671f\u306e\u8133\u6ce2\u691c\u67fb\u3068\u7ba1\u7406\u304c\u91cd\u8981\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/autism-spectrum-disorder-genetics\/\">\u81ea\u9589\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u75c7<\/a>\uff08ASD\uff09\u7684\u50be\u5411\uff1a<\/strong> \u793e\u4f1a\u7684\u76f8\u4e92\u4f5c\u7528\u306e\u56f0\u96e3\u3084\u3001\u7279\u5b9a\u306e\u3053\u3060\u308f\u308a\u3001\u611f\u899a\u904e\u654f\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u7b4b\u7dca\u5f35\u4f4e\u4e0b\uff1a<\/strong> \u5168\u8eab\u306e\u7b4b\u529b\u304c\u5f31\u304f\u3001\u75b2\u308c\u3084\u3059\u3044\u3001\u3042\u308b\u3044\u306f\u59ff\u52e2\u306e\u4fdd\u6301\u304c\u96e3\u3057\u3044\u3068\u3044\u3063\u305f\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u5fae\u7d30\u306a\u9854\u8c8c\u306e\u7279\u5fb4\uff1a<\/strong> \u9855\u8457\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u5e83\u3044\u984d\u3084\u8033\u306e\u5f62\u614b\u7570\u5e38\u306a\u3069\u304c\u5831\u544a\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n<!--nipt_mono-->\r\n<div class=\"nipt-mono\">\r\n    <div class=\"nipt-mono-btn\">\r\n        <a href=\"\/nipt\/nipt-mono\/\">\r\n            <img decoding=\"async\" loading=\"lazy\" src=\"\/nipt\/wp-content\/uploads\/2026\/03\/NIPT-MONO.webp\" alt=\"NIPT-MONO\u3067\u8abf\u3079\u3089\u308c\u307e\u3059\">\r\n         <\/a>\r\n    <\/div>\r\n<\/div>\r\n\r\n<style>\r\n.nipt-mono {\r\n    text-align: center; \/* \u89aa\u8981\u7d20\u3067\u6a2a\u4e2d\u592e *\/\r\n}\r\n.nipt-mono a img {\r\n    display: inline-block; \/* \u753b\u50cf\u3092\u30a4\u30f3\u30e9\u30a4\u30f3\u30d6\u30ed\u30c3\u30af\u5316\u3057\u3066 text-align \u306b\u53cd\u6620 *\/\r\n    width: 333px;\r\n}\r\n<\/style>\r\n<!--\/nipt_mono-->\r\n\r\n\n\n\n\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_%E8%A8%BA%E6%96%AD%E3%83%97%E3%83%AD%E3%82%BB%E3%82%B9%E3%81%A8%E6%9C%80%E6%96%B0%E3%81%AE%E6%A4%9C%E6%9F%BB%E6%89%8B%E6%B3%95\"><\/span><strong>3. \u8a3a\u65ad\u30d7\u30ed\u30bb\u30b9\u3068\u6700\u65b0\u306e\u691c\u67fb\u624b\u6cd5<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>BBSOAS\u306f\u75c7\u72b6\u304c\u591a\u5c90\u306b\u308f\u305f\u308b\u305f\u3081\u3001\u81e8\u5e8a\u75c7\u72b6\u306e\u307f\u3067\u78ba\u5b9a\u8a3a\u65ad\u3092\u4e0b\u3059\u3053\u3068\u306f\u56f0\u96e3\u3067\u3059\u3002\u73fe\u4ee3\u533b\u5b66\u306b\u304a\u3044\u3066\u306f\u3001\u4ee5\u4e0b\u306e\u30b9\u30c6\u30c3\u30d7\u3092\u7d4c\u3066\u8a3a\u65ad\u306b\u81f3\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E9%81%BA%E4%BC%9D%E5%AD%90%E6%A4%9C%E6%9F%BB%EF%BC%88%E7%A2%BA%E5%AE%9A%E8%A8%BA%E6%96%AD%E3%81%AE%E3%82%B4%E3%83%BC%E3%83%AB%E3%83%89%E3%82%B9%E3%82%BF%E3%83%B3%E3%83%80%E3%83%BC%E3%83%89%EF%BC%89\"><\/span><strong>\u907a\u4f1d\u5b50\u691c\u67fb\uff08\u78ba\u5b9a\u8a3a\u65ad\u306e\u30b4\u30fc\u30eb\u30c9\u30b9\u30bf\u30f3\u30c0\u30fc\u30c9\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u73fe\u5728\u3001BBSOAS\u306e\u552f\u4e00\u306e\u78ba\u5b9a\u8a3a\u65ad\u6cd5\u306f\u907a\u4f1d\u5b66\u7684\u691c\u67fb\u3067\u3059\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\uff1a<\/strong> \u5168\u30a8\u30af\u30bd\u30fc\u30e0\u89e3\u6790\uff08WES\uff09\u3084\u5168\u30b2\u30ce\u30e0\u89e3\u6790\uff08WGS\uff09\u306b\u3088\u308a\u3001NR2F1\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3092\u7279\u5b9a\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/amniocentesis-microarray\/\">\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4<\/a>\u691c\u67fb\uff1a<\/strong> \u907a\u4f1d\u5b50\u306e\u5fae\u7d30\u306a\u6b20\u5931\uff08\u30b3\u30d4\u30fc\u6570\u591a\u578b\uff09\u3092\u691c\u51fa\u3059\u308b\u306e\u306b\u6709\u52b9\u3067\u3059\u3002<\/li>\n<\/ol>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%87%A8%E5%BA%8A%E7%9A%84%E8%A9%95%E4%BE%A1\"><\/span><strong>\u81e8\u5e8a\u7684\u8a55\u4fa1<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u773c\u79d1\u7684\u8a55\u4fa1\uff1a<\/strong> \u773c\u5e95\u691c\u67fb\u3001\u8996\u899a\u8a98\u767a\u96fb\u4f4d\uff08VEP\uff09\u691c\u67fb\u3092\u884c\u3044\u3001\u8996\u795e\u7d4c\u306e\u4f1d\u5c0e\u6a5f\u80fd\u3092\u8a55\u4fa1\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>MRI\u691c\u67fb\uff1a<\/strong> \u8133\u306e\u69cb\u9020\u7684\u7570\u5e38\uff08\u8133\u6881\u306e\u8584\u5316\u3001\u767d\u8cea\u306e\u6e1b\u5c11\u306a\u3069\uff09\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u767a\u9054\u8a55\u4fa1\uff1a<\/strong> \u5c02\u9580\u306e\u5fc3\u7406\u58eb\u3084\u5c0f\u5150\u79d1\u533b\u306b\u3088\u308b\u767a\u9054\u6307\u6570\u306e\u6e2c\u5b9a\u3092\u884c\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/nipt\/wp-content\/uploads\/2025\/09\/4637647_s-4.webp\" alt=\"\u533b\u8005\" class=\"wp-image-116470\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"4_%E6%B2%BB%E7%99%82%E3%81%A8%E3%83%9E%E3%83%8D%E3%82%B8%E3%83%A1%E3%83%B3%E3%83%88%EF%BC%9A%E3%83%81%E3%83%BC%E3%83%A0%E5%8C%BB%E7%99%82%E3%81%AE%E9%87%8D%E8%A6%81%E6%80%A7\"><\/span><strong>4. \u6cbb\u7642\u3068\u30de\u30cd\u30b8\u30e1\u30f3\u30c8\uff1a\u30c1\u30fc\u30e0\u533b\u7642\u306e\u91cd\u8981\u6027<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u73fe\u6642\u70b9\u3067\u306f\u3001BBSOAS\u306e\u6839\u672c\u7684\u306a\u539f\u56e0\uff08\u907a\u4f1d\u5b50\u5909\u7570\uff09\u3092\u4fee\u5fa9\u3059\u308b\u6cbb\u7642\u6cd5\u306f\u78ba\u7acb\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u305d\u306e\u305f\u3081\u3001\u500b\u3005\u306e\u75c7\u72b6\u306b\u5408\u308f\u305b\u305f<strong>\u5bfe\u75c7\u7642\u6cd5<\/strong>\u3068<strong>\u7642\u80b2\u7684\u4ecb\u5165<\/strong>\u304c\u4e2d\u5fc3\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%A4%9A%E8%81%B7%E7%A8%AE%E9%80%A3%E6%90%BA%E3%81%AB%E3%82%88%E3%82%8B%E5%8C%85%E6%8B%AC%E7%9A%84%E3%82%B1%E3%82%A2\"><\/span><strong>\u591a\u8077\u7a2e\u9023\u643a\u306b\u3088\u308b\u5305\u62ec\u7684\u30b1\u30a2<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>BBSOAS\u306e\u30b1\u30a2\u306b\u306f\u3001\u5404\u5206\u91ce\u306e\u5c02\u9580\u5bb6\u304c\u9023\u643a\u3059\u308b\u30c1\u30fc\u30e0\u533b\u7642\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5c0f\u5150\u795e\u7d4c\u79d1\uff1a<\/strong> \u3066\u3093\u304b\u3093\u306e\u7ba1\u7406\u3001\u767a\u9054\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3002<\/li>\n\n\n\n<li><strong>\u773c\u79d1\u30fb\u30ed\u30fc\u30d3\u30b8\u30e7\u30f3\u30b1\u30a2\uff1a<\/strong> \u8996\u529b\u306e\u6700\u5927\u9650\u306e\u6d3b\u7528\u3001\u8996\u899a\u88dc\u52a9\u5177\u306e\u5c0e\u5165\u3002<\/li>\n\n\n\n<li><strong>\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\uff1a<\/strong>\n<ul class=\"wp-block-list\">\n<li><strong>\u7406\u5b66\u7642\u6cd5\uff08PT\uff09\uff1a<\/strong> \u7b4b\u529b\u5f37\u5316\u3001\u6b69\u884c\u8a13\u7df4\u3002<\/li>\n\n\n\n<li><strong>\u4f5c\u696d\u7642\u6cd5\uff08OT\uff09\uff1a<\/strong> \u624b\u5148\u306e\u52d5\u4f5c\u3001\u65e5\u5e38\u751f\u6d3b\u52d5\u4f5c\u306e\u8a13\u7df4\u3002<\/li>\n\n\n\n<li><strong>\u8a00\u8a9e\u8074\u899a\u7642\u6cd5\uff08ST\uff09\uff1a<\/strong> \u8a00\u8a9e\u7372\u5f97\u3001\u6442\u98df\u30fb\u56a5\u4e0b\u6307\u5c0e\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u7279\u5225\u652f\u63f4\u6559\u80b2\uff1a<\/strong> \u500b\u3005\u306e\u767a\u9054\u6bb5\u968e\u306b\u5fdc\u3058\u305f\u5b66\u7fd2\u74b0\u5883\u306e\u6574\u5099\u3002<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%97%A9%E6%9C%9F%E4%BB%8B%E5%85%A5%E3%81%AE%E6%84%8F%E7%BE%A9\"><\/span><strong>\u65e9\u671f\u4ecb\u5165\u306e\u610f\u7fa9<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u8133\u306e\u53ef\u5851\u6027\u304c\u9ad8\u3044\u5e7c\u5150\u671f\u304b\u3089\u306e\u65e9\u671f\u4ecb\u5165\u306f\u3001\u5c06\u6765\u7684\u306aQOL\uff08\u751f\u6d3b\u306e\u8cea\uff09\u5411\u4e0a\u306b\u5927\u304d\u304f\u5bc4\u4e0e\u3057\u307e\u3059\u3002\u7279\u306b\u8996\u899a\u3068\u904b\u52d5\u306e\u4e21\u9762\u304b\u3089\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u3001\u5916\u754c\u3068\u306e\u95a2\u308f\u308a\u3092\u6df1\u3081\u308b\u305f\u3081\u306b\u6975\u3081\u3066\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"5_%E6%9C%AA%E6%9D%A5%E3%81%B8%E3%81%AE%E5%B1%95%E6%9C%9B%EF%BC%9A%E7%A0%94%E7%A9%B6%E3%81%AE%E6%9C%80%E5%89%8D%E7%B7%9A\"><\/span><strong>5. \u672a\u6765\u3078\u306e\u5c55\u671b\uff1a\u7814\u7a76\u306e\u6700\u524d\u7dda<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>BBSOAS\u306e\u89e3\u660e\u306b\u5411\u3051\u305f\u7814\u7a76\u306f\u3001\u73fe\u5728\u3082\u4e16\u754c\u4e2d\u3067\u7cbe\u529b\u7684\u306b\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%96%BE%E6%82%A3%E3%83%A2%E3%83%87%E3%83%AB%E3%81%AE%E7%A0%94%E7%A9%B6\"><\/span><strong>\u75be\u60a3\u30e2\u30c7\u30eb\u306e\u7814\u7a76<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>iPS\u7d30\u80de\uff08\u4eba\u5de5\u591a\u80fd\u6027\u5e79\u7d30\u80de\uff09\u3092\u7528\u3044\u305f\u795e\u7d4c\u5206\u5316\u30e2\u30c7\u30eb\u3084\u3001\u30de\u30a6\u30b9\u7b49\u306e\u52d5\u7269\u30e2\u30c7\u30eb\u3092\u7528\u3044\u305f\u7814\u7a76\u306b\u3088\u308a\u3001NR2F1\u5909\u7570\u304c\u3069\u306e\u3088\u3046\u306b\u8133\u5f62\u6210\u3092\u963b\u5bb3\u3059\u308b\u306e\u304b\u3001\u305d\u306e\u8a73\u7d30\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u89e3\u660e\u3055\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%89%B5%E8%96%AC%E3%81%A8%E9%81%BA%E4%BC%9D%E5%AD%90%E6%B2%BB%E7%99%82%E3%81%AE%E5%8F%AF%E8%83%BD%E6%80%A7\"><\/span><strong>\u5275\u85ac\u3068\u907a\u4f1d\u5b50\u6cbb\u7642\u306e\u53ef\u80fd\u6027<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u5c06\u6765\u7684\u306b\u306f\u3001\u4e0d\u8db3\u3057\u3066\u3044\u308bNR2F1\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u3092\u88dc\u5b8c\u3059\u308b\u5316\u5408\u7269\u306e\u63a2\u7d22\u3084\u3001\u907a\u4f1d\u5b50\u6cbb\u7642\uff08mRNA\u7642\u6cd5\u3084\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u306e\u5fdc\u7528\uff09\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306f\u307e\u3060\u57fa\u790e\u7814\u7a76\u306e\u6bb5\u968e\u3067\u3059\u304c\u3001\u5e0c\u5c11\u75be\u60a3\u6cbb\u7642\u306e\u30d1\u30e9\u30c0\u30a4\u30e0\u30b7\u30d5\u30c8\u304c\u8d77\u304d\u3064\u3064\u3042\u308b\u4eca\u3001\u5e0c\u671b\u306e\u5149\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%82%A3%E8%80%85%E3%83%AC%E3%82%B8%E3%82%B9%E3%83%88%E3%83%AA%E3%81%A8%E3%82%B3%E3%83%9F%E3%83%A5%E3%83%8B%E3%83%86%E3%82%A3\"><\/span><strong>\u60a3\u8005\u30ec\u30b8\u30b9\u30c8\u30ea\u3068\u30b3\u30df\u30e5\u30cb\u30c6\u30a3<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u5e0c\u5c11\u75be\u60a3\u306b\u304a\u3044\u3066\u306f\u3001\u60a3\u8005\u30c7\u30fc\u30bf\u306e\u84c4\u7a4d\u304c\u7814\u7a76\u3092\u52a0\u901f\u3055\u305b\u307e\u3059\u3002\u4e16\u754c\u7684\u306a\u60a3\u8005\u30ec\u30b8\u30b9\u30c8\u30ea\u306e\u6574\u5099\u306b\u3088\u308a\u3001\u81ea\u7136\u6b74\uff08\u75be\u60a3\u306e\u7d4c\u904e\uff09\u306e\u628a\u63e1\u304c\u9032\u307f\u3001\u3088\u308a\u9069\u5207\u306a\u81e8\u5e8a\u8a66\u9a13\u306e\u30c7\u30b6\u30a4\u30f3\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u5bb6\u65cf\u4f1a\u306a\u3069\u306e\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u306f\u3001\u60c5\u5831\u306e\u5171\u6709\u3060\u3051\u3067\u306a\u304f\u3001\u7cbe\u795e\u7684\u306a\u652f\u3048\u3068\u3057\u3066\u3082\u5927\u304d\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%B5%90%E8%AB%96%EF%BC%9A%E7%90%86%E8%A7%A3%E3%81%A8%E5%85%B1%E7%94%9F%E3%81%AE%E3%81%9F%E3%82%81%E3%81%AB\"><\/span><strong>\u7d50\u8ad6\uff1a\u7406\u89e3\u3068\u5171\u751f\u306e\u305f\u3081\u306b<\/strong><span 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